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Post-translational modifications (PTMs) are pivotal in modulating protein function and cellular processes. However, experimental identification of PTM sites remains costly and labor-intensive. Recent advances in artificial intelligence (AI) have enabled accura…
pubmed
Ran J, Zhang X, Wang Y, Chen S 等
2026 Aug 18
置信度 0.82
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Text-conditioned generation of volumetric computed tomography (CT) from radiology reports is limited by the absence of explicit spatial information. Retrieval-augmented methods provide anatomical guidance, but existing approaches rely on a single nearest-neigh…
pubmed
Hou J, Wang S, Zhang Y, Liu J 等
2026 Aug 18
置信度 0.82
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Thermal ablation (TA), including microwave ablation, radiofrequency ablation, and cryoablation, is increasingly used as a surgical alternative for T1a renal cell carcinoma (RCC), particularly in lesions measuring ≤ 3 cm. In this revie…
pubmed
Sugawara S, Kurokawa R, Ide S, Yanagawa M 等
2026 Aug 18
置信度 0.82
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Brain cancer is one of the most challenging malignancies and a major contributor to worldwide morbidity and mortality. Glioblastoma, the most aggressive adult brain tumor, is associated with poor prognosis despite conventional therapies such as surgery, chemot…
pubmed
Roslei ASM, Huri HZ, Pratama DAOA, Azemi AK 等
2026 Aug 18
置信度 0.82
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Artificial intelligence (AI) is increasingly being integrated into robotic urologic surgery. However, existing literature remains fragmented across different technological domains. This scoping review aimed to systematically map and synthesize current evidence…
pubmed
Cei F, Arang H, Layne E, Ganjavi C 等
2026 Aug 18
置信度 0.82
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Weather and climate shape every aspect of our lives, yet for decades they have been studied as separate worlds-one concerned with what happens tomorrow, the other with what awaits us over the coming decades. This long-standing divide has slowed progress in bot…
pubmed
Camps-Valls G, Carrassi A, de Melo Viríssimo F, Debeire K 等
2026 Aug 18
置信度 0.82
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Microbial source tracking (MST) has become important in environmental ecology, food safety, and forensic investigation. With advances in microbiome technologies, MST has shifted from single-indicator methods to community-level inference, creating demand for st…
pubmed
Li J, Feng K, Wang L, Hu Q 等
2026 Aug 18
置信度 0.82
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Cross-border collaboration in healthcare has become increasingly important in the context of European integration, particularly in border regions where institutional and health system interactions are most pronounced. These regions offer opportunities for join…
pubmed
Puhlemann R, Maharaj AD, Homann A, Pérez Fortis A 等
2026 Aug 18
置信度 0.82
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Despite a general improvement in the HIV burden over the past two decades, gendered social determinants including intimate partner violence (IPV) continue to affect women's vulnerability to HIV, which could be further exacerbated as resources dwindle over the …
pubmed
GBD 2023 HIV Collaborators
2026 Aug 18
置信度 0.82
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WHO's Global Oral Health Action Plan (GOHAP) targets include a 10% relative reduction in the combined prevalence of main oral conditions by 2030. The first GOHAP evaluation was planned for 2023, with subsequent evaluations scheduled for 2026 and 2030. The aim …
pubmed
GBD 2023 Oral Disorders Collaborators
2026 Sep
置信度 0.82
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Understanding the size, gender composition, and cadre mix of the health workforce and how it has evolved across time and locations can inform policies for planning, recruitment, training, and retention of human resources for health (HRH), and improvement of ac…
pubmed
GBD 2023 Human Resources for Health Collaborators
2026 Sep
置信度 0.82
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Heart failure (HF) is a long-term condition that often causes repeated hospital visits and requires close monitoring. Cardiac troponin I (cTnI) and cardiac troponin T (cTnT) are widely known as markers of myocardial infarction, but in HF they can also show ong…
pubmed
Akshay Rangnath N, Sankar K, Agrawal PS, Panchabudhe HM 等
2026 Aug 15
置信度 0.82
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The lack of spatiotemporal precision in conventional physiological monitoring and agrochemical application hinders real-time plant intervention. Plant microneedles serve as a minimally invasive biointerface capable of fluid sampling, in situ sensing, and targe…
pubmed
Xue M, Li X, Wang J, Gao B
2026 Aug 8
置信度 0.82
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Digital health technologies, including telemedicine, electronic medical records, digital health tools (DHTs), and AI, are transforming European primary care, but evidence on how general practitioners (GPs) experience these tools remains fragmented.
pubmed
Fuger JM, Niehoff L, Zelko E
2026 Aug 18
置信度 0.82
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Advanced HIV disease remains a major global health concern, with nearly 40.8 million people living with HIV as of 2024. Antiretroviral therapy has improved outcomes, but its success depends on timely intervention, adherence, and retention in care. AI, includin…
pubmed
Yehadji D, Hofmann M, Isaakidis P, Alidou S 等
2026 Aug 18
置信度 0.82
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pubmed
Moher D, Page M, McKenzie J, Takwoingi Y 等
2026 Aug 18
置信度 0.82
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The advent of high-throughput sequencing technologies has revolutionized cardiovascular genetics, generating vast amounts of data. A major challenge in the genomic era is the efficient and accurate identification of causative genetic variants associated with c…
pubmed
De Paoli F, Nicora G, Galanti K, Gonzales CS 等
2026 Aug
置信度 0.82
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Community health workers (CHWs) play increasingly important roles in vector-borne disease prevention globally, yet their contributions remain underutilized and poorly documented in the literature. Understanding how CHWs are deployed across the prevention conti…
pubmed
Sierra LA, Larson EK, Maldonado A, Ellingson K 等
2026 Aug
置信度 0.82
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Primary malignant bone tumours of the skeleton have a great diversity in their biological behaviour, and the most common in adolescence is osteosarcoma for which the diagnosis and therapeutic management are both a challenge. The use of machine and deep learnin…
pubmed
Himel GMS, Achuthan A, Mohamed YA, Khoo BE 等
2026
置信度 0.82
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To systematically review the current research status, knowledge structure, and development trends in the fields of dynamic gap balance and soft tissue balance in robot-assisted total knee arthroplasty (RATKA), identify the core research forces, hot topics, and…
pubmed
Zhang X, Wang J, Xiao L, Liu K
2026 Aug 18
置信度 0.82
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CKD patients are susceptible to pneumoperitoneum-induced renal injury; comparative outcomes of robotic versus laparoscopic inguinal hernia repair are unknown. Retrospective propensity score-matched cohort using TriNetX (184 HCOs; 2015-2026). CKD adults undergo…
pubmed
Hanna F, Bayomi D, Zaki ST, Dway A 等
2026 Aug 18
置信度 0.82
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Thrombospondin-2 (THBS2) has emerged as a pivotal yet paradoxical regulator within the breast cancer (BC) tumor microenvironment (TME). This review synthesizes current evidence to elucidate its context-dependent duality and its potential as a novel therapeutic…
pubmed
Wan X, Zhao X, Lin Y, Yang S 等
2026 Aug 18
置信度 0.82
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Following its discovery, radium was initially promoted as a therapeutic agent for a wide range of conditions, including skin disorders, allergies, visual problems, joint pain, and as a general health-enhancing remedy. However, subsequent research demonstrated …
pubmed
Charkiewicz AE, Djuricic I, Todorovic V, Nikliński J 等
2026 Aug 18
置信度 0.82
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Anode-free lithium metal batteries (AFLMBs) represent the ultimate solution to mankind's quest for the Holy Grail of batteries, where the cell-level energy density is maximized on the assumption that lithium (Li0) must be fully utilized with near 100% Coulombi…
pubmed
Choi S, Kim J, Seo J, Amine K 等
2026 Aug 18
置信度 0.82
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Chronic kidney disease (CKD) is projected to become one of the leading causes of premature mortality worldwide by 2050. Simultaneously, advances in CKM medicine, artificial intelligence (AI), molecular biology, and regenerative science are transforming nephrol…
pubmed
Soliman AR, Fayed A, El-Khashab S
2026 Aug 18
置信度 0.82
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Neuro-oncology generates complex clinical, imaging, and molecular data, yet datasets remain relatively small and fragmented across modalities and institutions. While "big data" is traditionally defined by large sample size, neuro-oncology datasets are often ch…
pubmed
Kapoor A, Alyakin A, Markert JE, Arias A 等
2026 Aug 18
置信度 0.82
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Diabetic foot infections (DFIs) are a significant public health problem, associated with a delayed healing process and high rates of recurrence, which culminates in amputation. Two main factors, antimicrobial resistance (AMR) and biofilm formation, are respons…
pubmed
Irbaz M, Hamood Z, Shahid S, Ghufran A 等
2026 Aug 18
置信度 0.82
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Global imaging demand now exceeds capacity due to an aging population, rising comorbidities, expanded indications for imaging, and workforce shortages. These pressures are reshaping national health care policy. At the same time, the competing demands to expand…
pubmed
Moy L, Vargas A, Gichoya JW, Lungren MP 等
2026 Aug
置信度 0.82
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Precision nutrition on a global scale necessitates an understanding of food not as static collections of so-called macronutrients but rather as dynamic and heterogeneous biochemical matrices. These complex non-linear interactions between food composition, gast…
pubmed
Agrawal K, Kumar N, Singh A, Lu C 等
2026 Aug 18
置信度 0.82
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This study examines secular trends in body size among women in a high-altitude Andean population in Nuñoa, Peru to evaluate the relative contributions of high-altitude adaptation versus political-economic and nutritional factors to the small body sizes pr…
pubmed
Hoke MK, Mayer NM, Wisniewski A, Leatherman TL
2026 Aug
置信度 0.82
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The advancement of precision medicine depends critically on well-defined molecular targets. Pathologically activated fibroblasts drive disease progression in cancer, fibrosis and chronic inflammation through sustained inflammation, extracellular matrix remodel…
pubmed
Liu J, Zhao X, Liu P, Yu J 等
2026 Aug 18
置信度 0.82
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Tamoxifen (TMX), a key selective estrogen receptor (ER) modulator used in hormone-dependent breast cancer therapy, undergoes extensive metabolism to produce active metabolites, including endoxifen (END), 4-hydroxytamoxifen (4HT), and N -desmethyltamoxifen (NDT…
pubmed
Barzani HAH, Omer RA, Abdulrahman NB, Othman HO 等
2026 Aug 18
置信度 0.82
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ObjectiveWith increasing emphasis on value-based healthcare and rising costs, it is essential to assess the economic impact of artificial intelligence (AI). This study systematically reviews the evidence on the cost-effectiveness of AI applications in healthca…
pubmed
Imani A, Monaghesh E
2026 Jul-Sep
置信度 0.82
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Triple-negative breast cancer (TNBC) is defined by profound heterogeneity, dormant metastatic reservoirs, and rapid therapy resistance. Building on our AI-Driven CRISPR Strategies in Breast Cancer framework, CRISPR-Cas9 is emerging as more than a gene-editing …
pubmed
Taki AG, Shareef A, Arora V, Oweis R 等
2026
置信度 0.82
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The field of nanotechnology has demonstrated considerable potential in the diagnosis and treatment of prostate cancer, particularly through the use of prostate-specific membrane antigen (PSMA)-targeted platforms and tumor microenvironment (TME)-responsive syst…
pubmed
Li W
2026
置信度 0.82
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Electrochemical biosensors (E-biosensors) represent a promising platform for the detection of biomolecules closely linked to human health. Among these, RNA targets are of particular importance, including viral RNA (essential for disease diagnostics and epidemi…
pubmed
Ojeda J, Torres-Salvador F, Ortiz-Rodriguez T, Chumbimuni-Torres K
2026 Oct 15
置信度 0.82
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The rapid integration of Artificial Intelligence (AI) in education is transforming teaching, learning, and professional development through personalized instruction, adaptive learning, and data-driven educational practices. However, in Pakistan and Saudi Arabi…
pubmed
Alyoussef IY, Dahri NA, Alhashmi KA, Al-Rahmi WM 等
2026
置信度 0.82
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Despite widespread development of prognostic risk stratification tools, their implementation in Australian healthcare remains poorly characterised. This review identified tools implemented for adults aged ≥40 years and examined their real-world use. Fol…
pubmed
Greene L, Brain J, Brown B, Burley CV 等
2026 Jul
置信度 0.82
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Dengue fever poses a pervasive, yet escalating public health burden in Mexico and abroad.
pubmed
Li H, Lee C, Sweeney S, Valafar H 等
2026
置信度 0.82
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Personality traits are stable individual differences linked to important life outcomes including mental health, occupational functioning, and interpersonal relationships, yet their neural bases remain poorly characterized. Prior electroencephalography (EEG) st…
pubmed
Zhang C, Liu Y, Long Y, Hu S 等
2026 Aug 17
置信度 0.82
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Matrix metalloproteinase-12 (MMP-12) is a macrophage-derived zinc-dependent endopeptidase that plays a critical role in extracellular matrix degradation, chronic inflammation, and tissue remodeling in pulmonary diseases. Increasing evidence has established MMP…
pubmed
Khade V, Singh S, Labhade S, Thomas A
2026 Aug 18
置信度 0.82
-
To evaluate the efficacy and safety of CagriSema, a fixed-dose combination of cagrilintide, a long-acting amylin analogue, and semaglutide, a Glucagon-Like Peptide-1 (GLP-1) receptor agonist, compared with placebo, cagrilintide, or semaglutide monotherapy in o…
pubmed
Khan BW, Agha SA, Qamar I, Khattak MH 等
2026 Aug 17
置信度 0.82
-
We are developing a cloud-based neurohealth data platform to aggregate and store data from large, complementary historical and ongoing studies focused on traumatic brain injury (TBI), a condition shaped by complex interactions among biological, environmental a…
pubmed
Kiefer AW, Sompalli S, Mihalik JP, Hubal R
2026 Aug 17
置信度 0.82
-
Advanced ovarian cancer survivorship requires multidisciplinary coordination. As patients use large language models (LLMs) as clinical navigators, essential professional roles may be inconsistently represented. This study evaluates the comprehensiveness, profe…
pubmed
İnan M, Akar İnan S, Bumin G, Aypak C
2026 Aug 17
置信度 0.82
-
Infections remain a major cause of morbidity and mortality among immunocompromised patients, particularly in the context of invasive fungal infections (IFIs), where outcomes are strongly dependent on host immune status. Despite advances in antifungal therapy, …
pubmed
Bracke C, Grafia I, Puerta-Alcalde P
2026 Aug 17
置信度 0.82
-
Canonical and noncanonical autophagic processes are integrated with innate and adaptive immunity and sterile or pathogen-induced inflammation. In canonical autophagy, double-membrane autophagosomes modified by ubiquitin-like ATG8 proteins in a process termed m…
pubmed
Deretic V
2026 Aug 17
置信度 0.82
-
In response to the increasingly demanding needs of healthcare today, the integration of digital technologies into nursing education has accelerated. Digital approaches such as simulation, virtual learning environments, and AI-supported applications have become…
pubmed
Ertem GS, Ergün S, Kaynak S, Bayram HÇ
2026 Aug 10
置信度 0.82
-
Tuberculosis (TB) remains a leading cause of infectious disease mortality worldwide, and treatment failure contributes to ongoing transmission, drug resistance, and poor clinical outcomes. Artificial intelligence (AI) and machine learning (ML) approaches have …
pubmed
Kamulegeya R, Nabatanzi R, Semugenze D, Mugala F 等
2026
置信度 0.82
-
Rift Valley fever virus (RVFV) is a zoonotic arbovirus transmitted by a wide range of mosquito vectors present across the African continent. RVFV has resulted in large-scale epidemics in East, West, southern, and northern Africa with additional epidemics affec…
pubmed
Dawes BE, Gerken KN, Bett B, LaBeaud AD
2026 Aug
置信度 0.82
-
This study employed bibliometric methods to delineate the evolutionary trajectory, core hotspots, and emerging fields of robotics in the surgical treatment of prostate cancer, aiming to provide a comprehensive cognitive framework for this area. Data were obtai…
pubmed
Zhang X, Wang L, Peng Y, Jin J 等
2026 Aug 17
置信度 0.82
-
Wildfires are increasing in frequency and intensity worldwide, with growing evidence linking wildfire exposure to adverse mental health outcomes. This scoping review aimed to summarize and critically assess the existing quantitative literature on wildfire-rela…
pubmed
Teigen KA, Coomes DM, Nori-Sarma A, Casey JA
2026 Aug 17
置信度 0.82
-
Advanced haemodynamic monitoring of cardiac index is restricted to selected high-risk cases, leaving most patients undergoing major surgery without real-time assessment. We aimed to develop and internally validate a simplified bedside score for continuous, min…
pubmed
Azem K, Heesen P, Aranbitski R, Ronen A 等
2026 Aug 17
置信度 0.82
-
Prostate magnetic resonance imaging (MRI) reporting is a high-impact communication task because small differences in lesion laterality, sector localization, lesion size, Prostate Imaging-Reporting and Data System (PI-RADS) categorization, or staging language c…
pubmed
Cavallo AU, Midolo E, D'Anna G, Fujiwara M 等
2026 Aug 17
置信度 0.82
-
Artificial intelligence (AI) is increasingly being integrated into oncology for applications including cancer detection, risk stratification, treatment planning, and clinical documentation. Concerningly, growing evidence demonstrates that AI systems can reprod…
pubmed
Srinivasan A, Sritharan DV, Aneja S, Richman IB
2026 Aug 17
置信度 0.82
-
Psychological wisdom research has shifted from characterizing rare exemplars and desired outcomes to specifying processes that support sound judgment under uncertainty. Yet it has advanced along two siloed research tracks: one on folk theories-cultural tools s…
pubmed
Grossmann I, Weststrate NM
2026 Aug 17
置信度 0.82
-
To systematically identify, appraise and synthesise artificial intelligence (AI) and machine-learning (ML) models that predict treatment response and clinical outcomes after intravesical bacillus Calmette-Guérin (BCG) in non-muscle-invasive bladder cancer…
pubmed
Cella L, Contieri R, Paciotti M, Fasulo V 等
2026 Aug 17
置信度 0.82
-
Health economic models (HEMs) provide a solid foundation for reimbursement policy decisions that shape patient access to new treatments and the allocation of scarce healthcare resources. Model development is labor-intensive and time-consuming, often requiring …
pubmed
Imre A, Nemeth B, Józwiak Á, Nagy B 等
2026 Aug 17
置信度 0.82
-
Echocardiography is one of the most commonly used diagnostic methods in cardiovascular diseases because it is non-invasive, widely available, and capable of providing real-time assessment of function and cardiac structure. Despite these advantages, conventiona…
pubmed
Skoczylas D, Deleska K, Chmura W, Buczynski DM 等
2026 Jul
置信度 0.82
-
Cardiovascular diseases (CVDs) continue to be a major cause of death and morbidity throughout the world, and there is an increasing need for better diagnostic and predictive approaches. Existing methods do not fully reflect complex clinical interactions, and n…
pubmed
G AS, Kulkarni AV, Sharma CK, Tank BY 等
2026 Jul
置信度 0.82
-
Remimazolam, an ultra short-acting benzodiazepine with a rapid onset and predictable recovery, is increasingly recognized as an alternative to midazolam. We performed a systematic review and meta-analysis to assess the safety and efficacy outcomes of remimazol…
pubmed
Bahnasy S, Saleh AO, Ababneh IA, Fahim B 等
2026 Aug 17
置信度 0.82
-
pubmed
Kinsey LE, Vogel-Eyny A, Botero V, Kuns MC 等
2026 Aug 16
置信度 0.82
-
This study characterized nationwide trends, demographic distributions, and regional disparities in cardiac anesthesia and intraoperative transesophageal echocardiography (ITEE) in Japan.
pubmed
Kido M, Nakayama Y, Yan L, Nakajima Y 等
2026 Aug 16
置信度 0.82
-
Machine learning (ML) provides a promising approach to predict adverse perinatal outcomes, supporting early intervention to reduce neonatal morbidity and mortality. There has been a surge of publications using ML algorithms applied to routine clinical data to …
pubmed
Zhang J, Daniel N, Tiranti A, Li X 等
2026 Aug
置信度 0.82
-
Middle East respiratory syndrome coronavirus (MERS-CoV) remains a low-incidence but high-consequence zoonotic coronavirus threat. Since its identification in Saudi Arabia in 2012, more than 2600 laboratory-confirmed cases have been reported from 27 countries, …
pubmed
Azhar EI, Alqahtani M, Assiri AM, Al-Abri SS 等
2026 Aug 15
置信度 0.82
-
Historically the development of amyloid-β plaques and tau neurofibrillary tangles have been used as the hallmarks of Alzheimer's disease (AD). However, there is increasing evidence suggests that these pathological hallmarks are secondary to deeper metabo…
pubmed
Anwer T, Verma A, Asiri A, Alaklobie M 等
2026 Aug 15
置信度 0.82
-
To explore the notion of post-humanism and the impact of artificial intelligence (AI) on society, nursing and healthcare.
pubmed
Richards DA
2026 Aug 15
置信度 0.82
-
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