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• Artificial Intelligence Readiness in Clinical Trial Operations: A Narrative Review and Site-Level Governance Framework.
  Background/Objectives: Artificial intelligence (AI) is increasingly introduced into clinical trial operations, but operational usefulness does not imply regulatory or site-level readiness. This review maps AI applications across trial operations and proposes a…
  pubmed Wójcik S, Rulkiewicz A, Domienik-Karłowicz J 2026 Aug 12 置信度 0.82
• Google Translate Voice App vs. Qualified Interpreters: An Exploratory Study of Clinical Accuracy in Real-World Speech/Voice Encounters.
  Background/Objectives : AI voice interpretation applications like Google Translate in speech/voice mode are increasingly used in clinical settings to address verbal language access challenges, yet evidence comparing their performance to qualified in-person med…
  pubmed Feinberg I, Lee-Laminack H, Tighe EL, Owoeye I 2026 Aug 11 置信度 0.82
• Artificial Intelligence Adoption in Public Health Practice: A Cross-Sectional Study of Practical Determinants Among Healthcare Professionals.
  Artificial intelligence (AI) is increasingly embedded in public health workflows, yet adoption among practitioners remains uneven and is shaped by knowledge, legal awareness, and operational barriers. This cross-sectional study characterised determinants of AI…
  pubmed Stoiacovici CA, Ilie AC, Marc F, Brad S 等 2026 Aug 10 置信度 0.82
• Age of Language Acquisition Affects Topology of Brain White Matter Network: A Diffusion Tensor Magnetic Resonance Imaging Study.
  In bilinguals, experience-based inter-individual differences, including language acquisition age, influence the functional and structural organization of the brain. Although many studies have explored the effects of age of acquisition on non-tonal languages, o…
  pubmed Zhang Y, Tu L, Omata K, Chen G 等 2026 Aug 18 置信度 0.82
• Authentic Assessment of Social-Emotional Development in Early Childhood: A Scoping Review.
  Background/Objectives : Authentic assessment-the systematic observation of naturally occurring social-emotional behavior by familiar caregivers-is increasingly mandated by international early childhood frameworks, yet the field lacks a comprehensive tool inven…
  pubmed Xia Y, Xu Y, Zhu L, Ai J 等 2026 置信度 0.82
• An Augmented Reality and AI-Based System for Contextual Appliance Guidance: Implications for Cognitive Accessibility and Assistive Interaction.
  Modern household appliances often present complex interfaces that can be difficult to use, especially for older adults, people with visual impairments, and users with mild cognitive difficulties. In such cases, interacting with appliances may require sustained…
  pubmed Hafezi K, Tafreshi AH, Napoli C, Randieri C 等 2026 Jul 24 置信度 0.82
• Multimodal Diagnostic Ultrasound for Congestion, Perfusion, and Ultrafiltration Tolerance in Maintenance Hemodialysis: A Narrative Review.
  Maintenance hemodialysis is characterized by repetitive changes in fluid distribution, blood pressure, and organ perfusion. Conventional clinical examination, empirical dry-weight adjustment, and biomarkers do not fully resolve the compartment-specific nature …
  pubmed Yin K, Sun J, Liu K 2026 Aug 21 置信度 0.82
• Non-Invasive Skin Cancer Diagnosis by Electrical Impedance Spectroscopy: Biophysics, Devices, Clinical Evidence, and Future Directions.
  Skin cancer represents a growing global health burden. Current diagnostic pathways combine clinical examination and dermoscopy with histopathological confirmation; however, overlap between benign and malignant lesions can create diagnostic uncertainty and lead…
  pubmed Yang J, Wu L, Xue H, Chai J 等 2026 Aug 21 置信度 0.82
• Unsupervised Machine Learning for the Identification of Latent First-Trimester Obstetric Phenotypes Associated with Maternal and Perinatal Morbidity.
  Background/Objectives : Artificial intelligence may improve obstetric risk stratification by identifying clinically meaningful patterns that are not captured by single-outcome prediction models. This study evaluated whether unsupervised machine learning applie…
  pubmed Cristofor AE, Carauleanu A, Vasilache IA, Condriuc I 等 2026 Aug 20 置信度 0.82
• Uncertainty-Aware AI-Assisted Diabetic Retinopathy Grading from Fundus Images with Ordinal Conformal Prediction.
  Background: Artificial intelligence (AI) systems for diabetic retinopathy (DR) grading require reliable uncertainty estimates when applied to fundus images outside the development dataset. We evaluated whether conformal prediction can provide structured set-va…
  pubmed Hasan U, Nayeem MA, Alghamdi TG 2026 Aug 19 置信度 0.82
• FedSwin-LHTP: Structure-Aware Hessian-Inspired Token Pruning for Efficient Federated Skin Lesion Classification.
  Background: Skin cancer encompasses a diverse range of malignancies and remains a significant global health challenge. Accurate machine-learning-assisted diagnosis can substantially improve patient outcomes through early detection and timely clinical intervent…
  pubmed Awais M, Junejo RH 2026 Aug 19 置信度 0.82
• Comparative Evaluation of ChatGPT-5.2, Claude Sonnet 4.5, and DeepSeek-V3.2 for Rosacea-Related Information: Accuracy, Reliability, Readability, and Reference Hallucinations.
  Background/Objectives: Rosacea is a chronic inflammatory skin disease that requires long-term management and continuous patient education regarding triggers, skincare practices, and treatment adherence. In recent years, patients have increasingly turned to onl…
  pubmed Uçar MT, Bostan E, Ortabağ T, Dönmez E 2026 Aug 18 置信度 0.82
• Artificial Intelligence-Assisted Structural Analysis of Bones with Paget's Disease of Bone and Osteoporosis: Lessons from Mouse Models.
  Background/Objectives: Paget's disease of bone (PDB) and osteoporosis are chronic metabolic bone disorders characterized by disrupted bone remodeling and increased skeletal fragility; however, the underlying mechanism of PDB remains poorly understood. Artifici…
  pubmed Liu J, Kan SY, Xin X, Chen T 等 2026 Aug 18 置信度 0.82
• Automated Multimodal Sleep Staging Using DWT-Based Wavelet Decomposition and Explainable Machine Learning with Signal Sculpting Topographies.
  Objectives : Sleep staging from polysomnographic (PSG) recordings is clinically critical for diagnosing sleep-related disorders, yet manual scoring by certified technologists remains time-consuming, costly, and subject to inter-rater variability. Methods : Thi…
  pubmed Sarker AS, Samir KMM, Shakib ZK, Morol MK 等 2026 Aug 17 置信度 0.82
• Deep Learning for the Assessment of Alveolar Bone Loss on Intraoral Radiographs: A Systematic Review.
  Background . Radiographic bone loss is a primary determinant of periodontitis stage. Intraoral radiographs (periapical and bitewing) are the standard projections for assessing interproximal bone levels, yet their interpretation is subjective and poorly reprodu…
  pubmed Hashim NT, Gismalla BG, Rahman MM, Mohammed R 等 2026 Aug 14 置信度 0.82
• Diagnostic Accuracy of Novel AI-Based Software in the Detection of Dental Caries on Bitewing and Intraoral Periapical Radiographs.
  Background: Dental caries detection using intraoral radiographs is essential for early diagnosis but may be affected by observer variability. Artificial intelligence (AI)-based systems have emerged as potential tools to improve diagnostic consistency. This stu…
  pubmed Sujanamulk B, Almeshari AA, Takkella BK, Barayan MA 等 2026 Aug 14 置信度 0.82
• Large Language Model Decision Support for Cranial CT in Pediatric Head Trauma.
  Background : Pediatric head trauma is a common reason for emergency department presentation. Although most children have minor injuries, a small proportion harbor clinically important traumatic brain injuries requiring urgent intervention. Artificial intellige…
  pubmed Cesur E, Halici A, Kurtoglu N 2026 Aug 14 置信度 0.82
• Optimizing In-Hospital Mortality Prediction After Cardiac Surgery: A Machine Learning Approach Using Feature Engineering for Imbalanced Data.
  Background/Objectives: Cardiac surgery involves unique complexities that differ from those of general ICU populations. Traditional scoring systems often underperform due to the significant class imbalance between survival and mortality. This study utilized the…
  pubmed Kao PC, Wu CC, Yeh JC 2026 Aug 13 置信度 0.82
• Leading Towards a Translation Readiness Framework: A Systematic Review of Deep Learning Approaches for Eye Disease Diagnosis.
  Background: Artificial intelligence has significantly improved the diagnosis of retinal diseases using fundus and optical coherence tomography. However, the pathway between the accuracy of the models and their clinical application is still unclear. Objective: …
  pubmed Ali U, Imam AA, Apong RA 2026 Aug 7 置信度 0.82
• Immersive Virtual Reality for 3D Cephalometric Landmarking Across Low-Dose and Ultra-Low-Dose CBCT: A Pilot Comparison with a Conventional Computer Interface.
  Background: Three-dimensional cephalometric landmarking provides the spatial reference framework for computer-aided surgical simulation in craniomaxillofacial (CMF) surgery. Conventional workflows rely on two-dimensional computer interfaces (CIs), yet imaging …
  pubmed Järnstedt J, Mehtonen H, Kangas J, Naukkarinen H 等 2026 Aug 7 置信度 0.82
• Acquired Resistance to the PRMT5 Inhibitor Confers Collateral Sensitivity to MEK Inhibition in MTAP-Null Non-Small Cell Lung Cancer.
  Protein arginine methyltransferase 5 (PRMT5) is a synthetic lethal target in methylthioadenosine phosphorylase-deleted ( MTAP -null) cancers. Second-generation methylthioadenosine (MTA)-cooperative PRMT5 inhibitors preferentially target MTAP -null cells while …
  pubmed Fu R, Wang Y, Rehman I, Bedford E 等 2026 Aug 17 置信度 0.82
• Systems Bioengineering of Septic Shock Metabolism: Citrulline, β-Hydroxybutyrate and Plasma Biomarker-Based Phenotyping.
  Although advances in critical care have improved short-term outcomes, sepsis survivors continue to face substantial chronic morbidity and impaired long-term survival. Conventional threshold-based tools such as the Sequential Organ Failure Assessment (SOFA) and…
  pubmed Azamfirei L, Cehan VD, Cehan AR, Pui MC 等 2026 Aug 14 置信度 0.82
• Research Progress and Critical Challenges of Bioartificial Kidneys in Renal Replacement Therapy for End-Stage Renal Disease.
  Chronic kidney disease (CKD), one of the major global public health burdens, continues to exhibit a rising prevalence worldwide. The growing population of patients with end-stage renal disease (ESRD) has led to an increasing demand for renal replacement therap…
  pubmed Chen L, Zhang Q, Tu Y, Chen T 等 2026 Aug 10 置信度 0.82
• Pharmacological Modulation of the Kynurenine Pathway Using PF-04859989 Modulates PACAP Signaling in Migraine-Relevant Trigeminal Sensitization.
  Migraine is a disabling neurological disorder in which neuropeptides, particularly pituitary adenylate cyclase-activating polypeptide (PACAP), play pathogenic roles. The kynurenine pathway (KP) is increasingly implicated in migraine-related glutamatergic and n…
  pubmed Vágvölgyi-Sümegi E, Nagy-Grócz G, Galla Z, Cseh EK 等 2026 Aug 3 置信度 0.82
• SMAD4-BPIFA1 Axis Governs Airway Antiviral Defense in Myhre Syndrome.
  Myhre syndrome is a rare autosomal-dominant disorder caused by gain-of-function (GOF) variants in SMAD4. Although it is primarily recognized as a fibrotic disease, we and others have identified respiratory infection-associated morbidity as a major clinical bur…
  pubmed Di YP, Wen B, Li F, Tang F 等 2026 Jul 31 置信度 0.82
• AS1411-Induced Lipidomic Alterations and Therapeutic Insights in U-87 Glioblastoma Cells.
  Glioblastoma (GBM) is a devastating brain tumor heavily reliant on metabolic reprogramming for survival. The DNA aptamer AS1411 specifically targets cell-surface nucleolin (NCL), a protein overexpressed in GBM; however, its precise metabolic consequences remai…
  pubmed Kılıçkaya O, Şahin S 2026 Jul 25 置信度 0.82
• Development of a Novel AAV-Mediated microRNA Gene Therapy for Spatial Suppression of BACE1 to Improve Cognitive Function in Alzheimer's Disease Model Mice.
  The beta-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a promising and rational target for Alzheimer's disease (AD), but current clinical trials have been disappointing. Consequently, utilizing the intrinsic regulatory mechanisms of BACE1 d…
  pubmed Zhou Y, Diao Y, Yan Z, Shui X 等 2026 Jul 23 置信度 0.82
• A Trehalose-Based Phenotypic Screen Identifies Candidate Inhibitors of Mycobacterium tuberculosis Recycling Pathway.
  Background/Objectives : Phenotypic drug tolerance, distinct from genetic resistance, allows Mycobacterium tuberculosis (Mtb) to survive prolonged antibiotic exposure and contributes to treatment failure and relapse. The trehalose recycling pathway, mediated by…
  pubmed Vande Voorde R, Maves AM, Nelson D, Danelishvili L 2026 Jul 31 置信度 0.82
• Artificial Intelligence-Driven Dairy Quality Assessment: From Advanced Sensing Technologies to Explainable Intelligence.
  Artificial intelligence (AI) is transforming dairy quality assessment by enabling rapid, non-destructive, and data-driven monitoring across the dairy supply chain. Conventional analytical methods, although accurate, are often labor-intensive, time-consuming, a…
  pubmed Song X, Liang Z, Cheng C, Wu R 等 2026 置信度 0.82
• Computer Vision from Tea Cultivation to Quality Evaluation.
  Existing reviews on AI in tea production are either agriculture-generic or limited to isolated tasks. This review thoroughly compares vision technologies (RGB, hyperspectral, near-infrared, thermal, Light Detection and Ranging (LiDAR), Unmanned Aerial Vehicle …
  pubmed Chen Z, Wang J, Sun Y, Pang J 等 2026 Aug 17 置信度 0.82
• A Comparative Analysis of Bioactive Compounds and Heavy Metal Content in Table Eggs from Various Housing Systems.
  The growing demand for eggs from alternative housing systems is driven by perceived nutritional and welfare benefits. However, the trade-off between enhanced bioactive composition and exposure to environmental contaminants remains insufficiently explored. This…
  pubmed Drabik K, Zdun R, Skałecki P, Januś E 等 2026 Aug 14 置信度 0.82
• Comparative Characterization of Pork Jowl and Three Commercial Cuts from DLY Pigs: Instrumental Quality, Nutritional Composition, Water Distribution, and Volatile Profiles.
  This preliminary within-animal study focuses on the comprehensive characterization of pork jowl (PJ) by comparing it with pork belly (PB), Boston butt (BB), and spare ribs (SR) collected from the same ten castrated Duroc × Landrace × Yorkshire (DLY) …
  pubmed Xue S, Zhang W, Sun J, Yang B 等 2026 Aug 13 置信度 0.82
• Synergistic Optimization of In Vitro Digestibility and Sensory Quality of Moderately Milled Rice Based on the RiceMambaOpt Model.
  To address over-processing and limited process-control precision in rice manufacturing, this study developed an artificial intelligence (AI)-assisted optimization framework for rice milling. A data-driven predictive model was constructed to characterize the no…
  pubmed Li Z, Wen Z, Ma M, Niu W 等 2026 Aug 12 置信度 0.82
• Emerging Approaches in Pediatric Surgery: Current Evidence and Remaining Challenges.
  Pediatric surgery continues to incorporate minimally invasive techniques, image-guided procedures, artificial intelligence (AI), digital pathology, interventional radiology, and structured perioperative care [...].
  pubmed Di Fabrizio D, Bindi E, Cobellis G 2026 Aug 1 置信度 0.82
• Evolution of Clinical Fragility and Medication Burden in Children with Medical Complexity: A Longitudinal Cohort Study.
  Children with medical complexity (CMC) often suffer from chronic or evolving conditions that require increasingly complex treatment regimens over time, resulting in increased therapeutic and care burdens, costs, and the risk of adverse effects and medication e…
  pubmed Zanin A, Baratiri F, Brigiari G, Roverato B 等 2026 Jul 30 置信度 0.82
• Longitudinal Transcriptomic Remodeling of Adipose Tissue After Bariatric Surgery Revealed by Differential Expression and Explainable Machine Learning.
  Background: Bariatric surgery improves metabolic health, but long-term transcriptomic remodeling of white adipose tissue (WAT) after Roux-en-Y gastric bypass (RYGB) remains incompletely defined. This study aimed to characterize longitudinal WAT gene-expression…
  pubmed Allouch S, Sumon MSI, Naeem A, Hviid CVB 等 2026 Aug 19 置信度 0.82
• Lempel-Ziv Complexity and Structural Features of DNA Methylation Reveal Epigenetic Rejuvenation in Mouse Embryogenesis.
  Background : DNA methylation is a key epigenetic mechanism whose dynamics are closely linked to ageing. Modern epigenetic clocks predict biological age based on the average methylation level. The concept of "epigenetic rejuvenation" posits that at early stages…
  pubmed Timofeev AV, Bratchikov A, Anufriev A 2026 Aug 6 置信度 0.82
• Genome-Wide Identification of a Chromatin-Splicing Regulatory Axis Driven by DOT1L in MLL-Rearranged Acute Myeloid Leukemia.
  Background/Objectives: Aberrant H3K79 dimethylation (H3K79me2) by DOT1L is a defining feature of MLL-rearranged (MLLr) acute myeloid leukemia (AML), but whether this modification influences alternative splicing is unclear. We examined the relationship between …
  pubmed Liu Q, Yang B, Li T, Garcia R 等 2026 Jul 24 置信度 0.82
• Non-Coding RNAs in Cancer Liquid Biopsy: From Regulatory Networks to Functional Biomarkers for Precision Oncology.
  Liquid biopsy is now an established component of precision oncology, and its clinical implementation to date has been led by cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA) assays. These assays report genomic alterations, yet they may be limited by low…
  pubmed Pernagallo S, Tisato V, Gemmati D 2026 Jul 23 置信度 0.82
• Functional Characterization of Myelodysplastic Syndrome by Multiparameter Flow Cytometry: The Clinical Synergy Between Ki-67 and Bcl-2 and Their Potential Role in Diagnostics and Personalized Therapy.
  The diagnosis and clinical management of myelodysplastic neoplasms are increasingly challenged by the disease's inherent heterogeneity, particularly with respect to the diagnosis of low-grade variants. While standardized flow cytometric protocols traditionally…
  pubmed Wang SJ, Meel RAJNV, Mestrum SGC, Habets THPM 等 2026 Aug 17 置信度 0.82
• Exploring the Impact of T2-Weighted MRI Fat Saturation on Radiomics Stability for Brain Radionecrosis Prediction After Skull-Base Proton Therapy: A Pilot Study.
  Background/Objectives : In skull-base proton therapy, T2-weighted brain magnetic resonance (MR) imaging may be acquired with or without fat saturation (FS). The present study investigated the impact of this protocol variation on radiomics feature stability and…
  pubmed Thulasi Seetha S, Fontana G, Imparato S, Lillo S 等 2026 Aug 15 置信度 0.82
• Real-Time-Capable Detection of Glottic, Supraglottic and Hypopharyngeal Lesions Using Artificial Intelligence During Flexible Endoscopy.
  Background/Objectives : Supraglottic and hypopharyngeal carcinomas are aggressive malignancies that are often diagnosed at advanced stages. Timely recognition of these malignancies is influenced by many factors, such as endoscope quality and experience. This s…
  pubmed van Rhee NF, Wilmes CMLH, Krijnen HK, Hofman M 等 2026 Aug 13 置信度 0.82
• Artificial Intelligence Applications in MRI for the Diagnosis and Management of Osteonecrosis of the Femoral Head: A Comprehensive Review.
  Osteonecrosis of the femoral head (ONFH) is a progressive and potentially disabling condition caused by compromised blood supply to the femoral head, leading to bone necrosis and collapse. Early diagnosis is essential to enable joint-preserving interventions a…
  pubmed Denami F, Ammendolia A, de Sire A, Marotta N 等 2026 Aug 20 置信度 0.82
• LungCNET: A High-Performance Deep CNN Model for Lung Cancer Detection Evaluated Against Widely Used CNN Benchmarks.
  Lung cancer arises from mutations in lung cells, disrupting their normal growth cycle and leading to uncontrolled cell division. These rapidly dividing cells lose function and fail to form healthy lung tissue. Several factors contribute to the difficulty of di…
  pubmed Eskandarnia E, Adepoju P, Kiani K, Mansouri T 等 2026 Aug 18 置信度 0.82
• Pilot Study Employing a Machine Learning Approach as a Potential Method for Predicting Parkinson's Disease Using Voice as a Digital Biomarker and the SHAP Approach for Feature Engineering.
  Introduction : Voice-based digital biomarkers have emerged as a promising approach for distinguishing individuals with neurodegenerative disorders, particularly Parkinson's disease (PD), from healthy subjects (HS). With the increasing availability of smartphon…
  pubmed Rashidi M, Shah SAH, Coppola C, Buccoliero A 等 2026 Aug 13 置信度 0.82
• Applications of Wearable Sweat Biosensors in Sports Activities with Real-World Cases.
  Sports teams are constantly seeking advanced technologies to gain a competitive edge by enhancing athletic performance, accelerating recovery, and minimizing injury risk. Sweat serves as a readily accessible biofluid which enables non-invasive measurement of k…
  pubmed Yan J, Shi J, Zhang Z, Yang M 等 2026 Aug 11 置信度 0.82
• Advances and Clinical Translation Potentials of Functional Nanomaterials in Tissue Engineering.
  Functional nanomaterials, such as functionalized nanoparticles, nanofibers, nanocrystals, MXene and liposomes, have emerged as game-changers in tissue engineering, enabling precise modulation of cellular behaviors and dynamic biomimetic microenvironments. This…
  pubmed He Y, Peng Q 2026 Aug 10 置信度 0.82
• NucFuseRank: Dataset Fusion and Performance Ranking for Nuclei Instance Segmentation.
  Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning approaches have bee…
  pubmed Torbati N, Meshcheryakova A, Woitek R, Hatamikia S 等 2026 Jul 31 置信度 0.82
• Recent Advances in Lipid Nanoparticle-Mediated Respiratory and Gastrointestinal Mucosal Delivery of Nucleic Acids.
  The clinical translation of nucleic acids is severely hindered by multiple delivery barriers, such as enzymatic degradation, poor cellular uptake, endosomal entrapment, and rapid systemic clearance. Despite the remarkable therapeutic potential of these agents,…
  pubmed Liu Z, Fu J, Mo N, Yang J 等 2026 Jul 31 置信度 0.82
• Automated Skin Lesion and Cancer Detection Using Computer Vision: A Comprehensive Review.
  Detection of skin cancer has become an increasingly prevalent health issue for which there is a need for reliable methods of detection to improve patient outcomes, minimize delays in diagnosis, and ensure clinical referral. Advances in computer vision and arti…
  pubmed Sonune BS, Ramanathan U, Tulaskar DP, Nemane SG 等 2026 Jul 28 置信度 0.82
• Radiomics and Artificial Intelligence in Ovarian Endometriosis Imaging: A Systematic Review and Critical Appraisal of Emerging Evidence.
  Ovarian endometriosis is a common manifestation of endometriosis associated with chronic pelvic pain and infertility. Although transvaginal ultrasound and magnetic resonance imaging are central to diagnosis, challenging cases may benefit from more objective im…
  pubmed Telecan T, Capraș RD, Poenar ST, Sevan-Libotean R 等 2026 Jul 24 置信度 0.82
• Beyond Size and Class Balance: Alpha as a New Dataset Quality Metric for Deep Learning.
  In deep-learning-based image classification, achieving high performance requires diverse training sets. However, the current best practice-maximizing dataset size and class balance-does not guarantee dataset diversity. We hypothesized that, for a given model a…
  pubmed Couch JD, Arnaout R 2026 Jul 24 置信度 0.82
• AI-Driven Robotic PCI: A Perception-to-Action Framework for Coronary Guidewire Control.
  Robotic percutaneous coronary intervention (PCI) remains predominantly teleoperated, while the most demanding part of the procedure, guidewire navigation through a moving coronary tree under fluoroscopy, still depends on the continuous human interpretation of …
  pubmed Liu Z, Xu H, Ma J, Liu J 等 2026 Jul 23 置信度 0.82
• Faithful Explanation Regeneration via Cauchy-Schwarz Mixture Information Bottleneck.
  Large pretrained language models can generate fluent free-text explanations for natural language reasoning tasks, but these explanations may contain redundant, irrelevant, or unsupported information. In this paper, we propose a faithful explanation regeneratio…
  pubmed Wang Z, Du J 2026 Aug 10 置信度 0.82
• Lightweight Asymmetric Convolutional Residual Network for Efficient Motion Image Deblurring.
  Motion image deblurring remains challenging because many existing models rely on complex architectures, leading to high computational cost and parameter redundancy, particularly under non-uniform blur in real-world scenes. To mitigate these limitations, we pro…
  pubmed Li H, Yue Y, Li J, Guo Z 等 2026 Aug 10 置信度 0.82
• Undetected Error Bounds for Hybrid Integrity Protection Using Reed-Muller Codes, Algebraic Manipulation Detection, and Universal Hashing.
  Ensuring information integrity requires not only reducing decoding errors but also reducing the probability that corrupted data are accepted as valid. This research presents a hybrid integrity protection system that incorporates seeded universal hash verificat…
  pubmed Shavkatovich BA, Abduvaitov A, Isroil J, Husan K 等 2026 Aug 3 置信度 0.82
• Secreted protein combination GAPDH/S100A8/S100A9 from human expanded potential stem cells counteracts mesenchymal stromal cell senescence.
  Human mesenchymal stromal cells (hMSCs) remain the most clinically advanced adult stem cell source; however, their therapeutic potential is limited by rapid replicative senescence during ex vivo expansion. Replicative senescence in hMSCs is characterized by ce…
  pubmed Feng Q, Pang Q, Lu H, Liu Z 等 2026 Jul 30 置信度 0.82
• Current and future therapies for triple-negative breast cancer.
  Triple-negative breast cancer remains an aggressive and biologically heterogeneous breast cancer subtype. Although the therapeutic landscape has expanded, durable disease control remains clinically challenging in many settings. Existing reviews often organize …
  pubmed Wang ZX, Liu XY, Wu YX, Xiao YL 等 2026 Aug 26 置信度 0.82
• Physicians' perspectives on artificial intelligence in electrocardiography in clinical practice: a qualitative study.
  Artificial intelligence-enhanced electrocardiography (AI-ECG) may support ECG interpretation, prioritization, and workflow efficiency. ECGs are widely used, inexpensive, and often obtained with a low clinical threshold, meaning that AI-ECG may affect large num…
  pubmed Allgårdh G, Helgesson G, Kihlbom U 2026 Aug 26 置信度 0.82
• Clinicians' Perception and Management of Cancer Patients' Decision Making Burden.
  Clinicians in cancer care are increasingly expected to involve patients in treatment decision making. Some patients may feel burdened by such involvement. It is unclear how clinicians recognize and respond to patient burden in shared decision making (SDM).
  pubmed Huijgens FL, Henselmans I, Huisinga MJ, Diepenhorst GMP 等 2026 Aug 26 置信度 0.82
• From ANCA-mediated vascular injury to coronary microvascular and myocardial involvement in granulomatosis with polyangiitis: an immunocardiology perspective.
  Granulomatosis with polyangiitis (GPA) is a prototypical antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis characterized by necrotizing inflammation of small- and medium-sized vessels with granulomatous features. Although advances in immunosuppr…
  pubmed Lucki M, Grygiel-Górniak B, Lucka E, Iwańczyk S 等 2026 Aug 27 置信度 0.82
• GDLS-D: two-stage medical surface reconstruction via geometric diffusion least squares and iterative deformation optimization.
  Surface representations of anatomical structures are crucial for medical applications including preoperative planning and biomechanical simulations, yet current methods face challenges from limited datasets and staircase artifacts. This study proposes a traini…
  pubmed Shi J, He X, Chen S, Xing Y 等 2026 Aug 27 置信度 0.82
• Artificial intelligence and machine learning in photocatalytic nanomaterials: applications across diverse environmental pollutants.
  Escalating environmental pollution, particularly from persistent organic pollutants, dyes, pharmaceuticals, and other recalcitrant contaminants in wastewater and air, demands innovative, efficient, and sustainable remediation technologies. Nanomaterials-based …
  pubmed Gonfa F, Soromessa T 2026 Aug 27 置信度 0.82
• Prediction of human missense variant effects from functional evidence.
  Prediction of missense variant effects remains a critical bottleneck in both research and diagnostic genetics. Current predictors typically rely on clinical outcomes or population patterns rather than direct measures of functional impact, leading to limited ge…
  pubmed Kayaalp B, Çil K, Conil C, Cobat A 等 2026 Aug 26 置信度 0.82
• Multimodal AI Methods for Predicting Pathologic Complete Response in Breast Cancer.
  Neoadjuvant chemotherapy (NAC) can eliminate all invasive cancer in some breast cancer patients, achieving a pathologic complete response (pCR) that is associated with a better prognosis. Prediction of pCR from pre-treatment radiology imaging is challenging bu…
  pubmed Goyal M, Shukla T, Hassanpour S 2026 Aug 26 置信度 0.82
• EndoVLM: A Vision-Language Assistant for Gastrointestinal Endoscopy.
  Gastrointestinal endoscopy generates extensive high-resolution video data, posing significant challenges for efficient and accurate computer-aided diagnosis of gastrointestinal diseases. To address this, we propose EndoVLM (Endoscopy Vision-Language Model), a …
  pubmed Wang S, Liu C, Zhao T, Zhao B 2026 Aug 26 置信度 0.82
• Long-read sequencing reveals pre-meiotic gene conversion in sperm.
  Meiotic recombination is a fundamental process that generates genetic diversity by creating new combinations of existing alleles 1 . Whereas crossovers in humans are well characterized 2 , the more frequent non-crossovers that lead to gene conversion remain ch…
  pubmed Schweiger R, Lee S, Zhou C, Yang TP 等 2026 Aug 26 置信度 0.82
• TNF-α-responsive YAP1 promotes CCL20 expression in colorectal inflammation and cancer.
  Colitis-associated colorectal cancer (CAC) exemplifies how chronic intestinal inflammation can be converted into sustained epithelial programs and a permissive tumor microenvironment, yet the molecular linkage between inflammatory cytokine cues and chemokine o…
  pubmed Chen L, Ai F, Yu W, Xiang B 等 2026 Aug 10 置信度 0.82
• Health promoting spirulina platensis nanoparticles induce early embryonic loss in heat-stressed rabbit does.
  Heat stress poses a major constraint to rabbit production by impairing reproductive performance, compromising embryo survival, and increasing oxidative stress. Spirulina, known for its rich content of proteins, antioxidants, and bioactive compounds, has been p…
  pubmed Hanafi EM, Elnady IA, Shehab El-Din MI, Saber YHA 等 2026 Aug 26 置信度 0.82
• Inhibition of KDM5A/B promotes antitumor innate immune responses in HHV-8/KSHV-positive B-cell lymphomas.
  Histone methylation is a dynamic and reversible epigenetic modification that critically controls the progression of human diseases, including infections and cancers. Here we reported that histone lysine demethylases (KDMs) in the KDM5 family KDM5A/B play profo…
  pubmed Zhou D, Fiches GN, Wu Z, Eleya S 等 2026 Aug 22 置信度 0.82
• Core-sheath coupling controls flagellar curvature and motility in Leptospira.
  Spirochaete pathogens are among the most invasive bacteria known, causing syphilis, Lyme disease, and leptospirosis. Their tissue penetration depends on periplasmic flagellar filaments that, unlike other bacterial flagella, are encased in a spirochaete-specifi…
  pubmed San Martin F, Brady MR, Fule L, Nouchikian L 等 2026 Jul 25 置信度 0.82
• Oncogenic Kras targeting with MRTX1133 or Daraxonrasib specifically synergize with anti-CTLA4 to promote anti-tumor immunity in pancreatic cancer.
  Lack of sustained response to oncogenic Kras (Kras*) inhibition in pancreatic ductal adenocarcinoma (PDAC) underscores the need to identify effective combination therapies. Here, we demonstrate that Kras* targeting using MRTX1133 or Daraxonrasib recruits diver…
  pubmed Mahadevan KK, Maldonado AS, Li B, Bickert AA 等 2026 Jul 27 置信度 0.82
• Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion.
  We report the generation and propagation of not only the first heritable transgenic schistosome line but also a line that secretes a functional therapeutic protein in vivo. Using multiplexed CRISPR/Cas-mediated homology-directed knock-in targeted to a predicte…
  pubmed Ittiprasert W, Smout MJ, Mann VH, Moyle M 等 2026 Aug 26 置信度 0.82
• Structural and functional studies of inward rectifier Kir7.1 and its regulation by the Melanocortin-4 receptor.
  Hereditary defects in the function of the inwardly rectifying potassium channel Kir7.1 in the retinal pigment epithelium are associated with the ocular diseases retinitis pigmentosa, Leber congenital amaurosis, and snowflake vitreoretinal degeneration. However…
  pubmed Peisley A, Hernandez CC, Dahir NS, Koepping L 等 2026 Jul 27 置信度 0.82
• Scalable high resolution ancestry deconvolution for genomic data.
  As genome-wide association studies and genetic risk prediction models extend to globally diverse and admixed biobanks, accurate, scalable ancestry deconvolution, also called local ancestry inference (LAI), has become crucial. LAI assigns ancestry to each genom…
  pubmed Hilmarsson H, Kumar AS, Barrabés M, Rastogi R 等 2026 Jul 25 置信度 0.82
• Hyperbolic adaptive spatial-aware multivariate time series anomaly detection.
  Existing multivariate anomaly detection methods suffer from practical industrial limitations stemming from distribution assumptions, volatile data and scarce reliable anomaly labels. This study proposes a hyperbolic adaptive spatial-aware multivariate anomaly …
  pubmed Han J, Huo X, Xiao Y, Ye Z 等 2026 Jul 27 置信度 0.82
• Intelligent medical sensors for smart healthcare and precision medicine.
  Conventional medical sensors primarily function as passive transducers and often struggle to maintain accuracy and stability under complex physiological conditions. Their limited capacity for local data processing, adaptive compensation, and real-time interact…
  pubmed Wen J, Wu J, Yang Y, Wang L 等 2026 Aug 26 置信度 0.82
• Orai1 Contributes to Platelet-Activating Factor (PAF)-Induced Contraction in Association with Voltage-Dependent Ca(2+) Channel-Mediated Mechanisms in Guinea Pig Urinary Bladder Smooth Muscle.
  Platelet-activating factor (PAF) is known to induce smooth muscle contraction; however, its mechanisms in urinary bladder smooth muscle (UBSM) remain unclear. We investigated the involvement of Orai1 in PAF-induced contraction in guinea pig UBSM. PAF (10 -6 M)…
  pubmed Obara K, Kato D, Yuguchi M, Tanaka M 等 2026 置信度 0.82
• Architectural logic of the 3D genome: mechanisms of dysregulation and emerging cancer therapeutics.
  The three-dimensional (3D) genome provides an essential layer of organization that shapes genome function in space and time. Chromatin compartments and topologically associating domains (TADs) arise from the interplay between intrinsic properties of chromatin …
  pubmed Smith RG, Wilson HM, Schiela KL, Liu Y 2026 Aug 26 置信度 0.82
• A smartphone-integrated colorimetric platform with AI assistance for sensitive rutin detection based on spherical Cu(2)O/MXene quantum dots nanozymes.
  Artificial nanozymes integrate low cost and high sensitivity, and their rational design has become a research hotspot and core focus in the field. In this work, a novel high-sensitivity colorimetric detection platform was developed using MXene quantum dots (MQ…
  pubmed Guo Y, Liu F, Chen C, Li Z 等 2026 Oct 22 置信度 0.82
• Ambient Artificial Intelligence Scribes in Ambulatory Care: Patient Acceptability and Trust.
  BACKGROUND: Ambient artificial intelligence (AI) scribes may improve clinician-level outcomes (e.g., documentation burden) and patient experience. However, patients must agree to allow clinicians to use ambient AI scribes for these benefits to materialize. Wha…
  pubmed Nguyen OT, Afshar M, Jaeb MA, Ryan Baumann M 等 2026 Aug 置信度 0.82
• Trichosanthes kirilowii polysaccharides: A comprehensive review of structural characterization, bioactivities, and monosaccharide composition-based structure - activity relationships.
  Trichosanthes kirilowii polysaccharides (TKP), isolated from the seeds, peels, and roots, exhibit remarkable structural heterogeneity and diverse biological activities. This review systematically summarizes recent advances in the extraction, purification, stru…
  pubmed Xu X, Xiao J, Zhang H, Huang H 等 2026 Aug 26 置信度 0.82
• RNA biosensors in oncology: Mechanisms, Cancer-specific applications, and a Hallmark-aligned clinical roadmap.
  Cancer diagnosis continues to rely on invasive tissue sampling and static molecular assessments that cannot reflect the real time RNA alterations driving tumour progression. RNA biosensors are genetically encoded or synthetic devices that translate specific RN…
  pubmed Gamage A, Herath HMLPB, de Silva KMN, de Silva RM 2026 Aug 26 置信度 0.82
• Clinical phenotyping of bloodstream infections: a review of current evidence.
  Bloodstream infections (BSIs) are a leading cause of morbidity and mortality, yet their clinical heterogeneity continues to challenge effective patient stratification and treatment optimisation. In other heterogeneous conditions such as sepsis, data-driven cli…
  pubmed Vaselli NM, Isler B, Stewart A, Mathé P 等 2026 Aug 26 置信度 0.82
• Computational precision nutrition for sarcopenia and associated multimorbidity in ageing.
  Sarcopenia is the age-related progressive decline in both skeletal muscle mass and function. It acts as an exacerbator of multimorbidity, engaging in bidirectional pathological cycles with multiple chronic diseases, and contributes substantially to increased m…
  pubmed Fu G, Chen L, Wang Z, Fang H 2026 Aug 26 置信度 0.82
• Artificial intelligence across organ-on-a-chip workflows: current implementations and future approaches.
  Organ-on-a-Chip (OoC) systems use microfluidic and tissue engineering techniques to recreate key features of organ microenvironments. They have become a common platform for disease modeling and drug screening. As OoC technologies advance, they generate larger …
  pubmed Li J, Xin J, Qu L, Xu L 等 2026 Aug 26 置信度 0.82
• Identification of Der p1 inhibitors: Combining AI-based QSAR, molecular docking, molecular dynamics simulations and quantum physics.
  Immunotoxins represent promising therapeutics; they can be used as allergen-specific therapies. Der p1 is a major allergen produced by the house dust mite Dermatophagoides pteronyssinus responsible for allergic asthma and other allergic diseases. In spite of c…
  pubmed Kazem RA, Yahya M, Shuwaili M, Al-Khafaji K 2026 置信度 0.82
• Nursing students' critical engagement with generative AI in evidence-based practice education: A qualitative descriptive study.
  The rapid integration of generative artificial intelligence (GenAI) into nursing education presents both opportunities and challenges, yet empirical evidence on students' critical engagement with AI-generated content within assessment contexts remains limited.
  pubmed Sahay A, Adeleye A, Lane-Krebs K 2026 Aug 22 置信度 0.82
• A novel approach for liver steatosis assessment in ultrasound images using an adapted Vision-Language Foundation Model.
  Metabolic dysfunction-associated steatotic liver disease (MASLD) is among the most prevalent chronic liver diseases worldwide. B-mode ultrasound remains the first-line screening modality, yet its qualitative nature and inter-observer variability limit diagnost…
  pubmed Kresevic S, Giuffrè M, Bortolotto A, Bonazza D 等 2026 Aug 26 置信度 0.82
• CT scan range planning in clinical practice: An international survey of scan range extension, quality assurance, and AI integration.
  Computed tomography (CT) scan range planning is a modifiable determinant of radiation exposure but remains highly variable in clinical practice. This study aimed to characterize current practices, identify contributors to scan range extension, examine quality …
  pubmed Bani-Ahmad M, England A, McLaughlin L, Hadi YH 等 2026 Aug 26 置信度 0.82
• Correction: Using Psychological Artificial Intelligence (Tess) to Relieve Symptoms of Depression and Anxiety: Randomized Controlled Trial.
  [This corrects the article DOI: 10.2196/mental.9782.].
  pubmed Fulmer R, Joerin A, Gentile B, Lakerink L 等 2026 Aug 26 置信度 0.82
• Large Language Models for Patient Education in Cardiovascular Imaging: Prospective Observational Comparative Study.
  Large language models (LLMs) are increasingly used to support digital health communication, yet their reliability in patient-facing cardiovascular imaging education remains uncertain. Cardiovascular imaging involves complex terminology and procedural details t…
  pubmed Marey A, Pal B, Yaşar AB, Rath S 等 2026 Aug 26 置信度 0.82
• AI-Based Approaches to Refugee Mental Health Care: Systematic Integrative Review.
  Refugees and forcibly displaced populations experience elevated rates of mental health conditions, including posttraumatic stress disorder, depression, and anxiety, while facing substantial barriers to mental health care. AI has emerged as a promising approach…
  pubmed Kang H, Park S, Kim J, Kim O 等 2026 置信度 0.82
• Improvement of Clinical Practice Guideline Appraisal by Human Experts and AI Agents by Using Structured Guidance: Systematic Review, Meta-Analysis, and Validation Study.
  Rehabilitation clinical practice guidelines (CPGs) have increased rapidly, but inconsistent methodological quality limits their implementation. Although Appraisal of Guidelines for Research and Evaluation II (AGREE II) and Reporting Items for Practice Guidelin…
  pubmed Mao X, Wang J, Wang Z, Zhang Y 等 2026 置信度 0.82
• Sustained shrinkage of bilateral adrenal adenomas during long-term osilodrostat therapy.
  Surgery remains the first-line therapy for all forms of Cushing syndrome; medical therapy may be appropriate when surgery is not feasible or as adjunctive therapy in severe hypercortisolism.
  pubmed Messina E, Romanisio M, Gigante A, Parola C 等 2026 Aug 26 置信度 0.82
• A clinician-centered evaluation framework for large language models in patient education: Integrating the Technology Acceptance Model and Medical Condition Regard Scale.
  Inadequate post-care patient education contributes to preventable readmissions and adverse outcomes that disproportionately affect medically complex, high-need communities. Large language models (LLMs) show promise for generating personalized, plain-language p…
  pubmed Austria D, Williams GL, Girardo C, Arowolo MO 等 2026 Aug 25 置信度 0.82
• Ambient Artificial Intelligence Scribes in Urology: Early Lessons From a Single-System Implementation.
  pubmed Robinson EJ, Chen IK, Baecker AS, DeHaven ALH 等 2026 Aug 26 置信度 0.82
• Disseminated Cryptococcosis in a Liver Transplant Recipient: Case Report.
  pubmed Shen M, Zhu X, Lang J 2026 Aug 26 置信度 0.82
• Evaluating hybrid human-LLM coding workflows for qualitative research in medical education: A generalizability study.
  Large language models (LLMs) are increasingly proposed as deductive coders in qualitative research, but their measurement properties remain underexplored. This study applies generalizability theory to evaluate whether hybrid human-LLM workflow configurations c…
  pubmed Rush E, Karim MN, Yacu GS, Byram JN 等 2026 Aug 26 置信度 0.82
• Top-down feedback in deep neural networks leads to functional differences during audiovisual integration.
  Artificial neural networks (ANNs) are an important tool for studying neural computation, but many features of the brain are not captured by standard ANN architectures. One notable missing feature in most ANN models is top-down feedback, that is projections fro…
  pubmed Tugsbayar M, Li M, Muller EB, Richards B 2026 Aug 26 置信度 0.82