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• Identification of suicidal ideation in major depressive disorder: A machine learning approach with multimodal digital features.
  Current detection models for suicidal ideation (SI) among depressed patients have primarily relied on clinical and biological features. This study aims at enhancing the real-world applicability of these models by using multimodal digital features. Patients sel…
  pubmed Man MSY, Au ALM, Cheng CCW, Siew MKY 等 2026 Aug 置信度 0.82
• Fundamental limits incorporating logical reasoning into Shannon's information theory.
  A cornerstone of Shannon's famous information theory is the idea of decoupling the meaning of a message from its efficient transmission. In this article, we propose an extension of Shannon's communication model where the sender and receiver are assumed to have…
  pubmed Lastras LA, Lenchner J, Trager BM, Szpankowski W 等 2026 Sep 置信度 0.82
• The Mind From Within: Visceral Roots of Human Cognition.
  Humans think and act not only with the brain but also with the heart, lungs, gut, and other viscera, such as the bladder, long regarded as primarily vegetative. A fresh wave of experiments is revealing the role of cardiac-cycle phase and baroreceptor firing in…
  pubmed Monti A, Aglioti SM 2026 Aug 27 置信度 0.82
• Identifying Patients at Risk for Psychotherapy Dropout in Community Settings.
  Psychotherapy dropout poses a significant public health problem and is associated with depression relapse and illness persistence. Identifying who is at risk of psychotherapy dropout can guide personalized and scalable strategies to mitigate risk and improve o…
  pubmed Giber B, Sharma A, Broadie D, McCoy TH Jr 等 2026 Aug 3 置信度 0.82
• AS-TLC-Based High-Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor.
  The classical sequential workflow-individual compound screening, followed by stepwise design-synthesis-purification of derivatives-makes lead compound discovery time-consuming and cost-prohibitive. Herein, we developed Affinity Selection Thin-Layer Chromatogra…
  pubmed Wang M, Fu S, Xu Y, Gao J 等 2026 Aug 27 置信度 0.82
• Motion-induced fields near an idealized actively shielded MRI magnet: a reproducible reduced-order framework for scaling and sensitivity from 1.5 to 7 T.
  To present a transparent reduced-order electromagnetic framework for examining how an explicitly specified magnet geometry, movement trajectory, and body-conversion model affect movement-induced field estimates near MRI systems. The framework distinguishes dep…
  pubmed Vafapour H 2026 Aug 27 置信度 0.82
• Clinical significance of combining circulating tumor DNA and endoscopic response evaluation for esophageal squamous cell carcinoma.
  We previously demonstrated the usefulness of circulating tumor DNA (ctDNA) in blood for assessing tumor burden for esophageal squamous cell carcinoma (ESCC). We also found that endoscopic response evaluation predicted the prognosis of ESCC patients. In this st…
  pubmed Hoshi Y, Matsuda S, Nakamura K, Kawakubo H 等 2026 Aug 27 置信度 0.82
• A contrast-enhanced CMR-based risk score integrating microvascular obstruction and intramyocardial hemorrhage extent for prognostic evaluation.
  This study aims to compare the prognostic value of the extent of microvascular obstruction (MVO) combined with intramyocardial hemorrhage (IMH) for major adverse cardiovascular events (MACE) in patients with STEMI.
  pubmed Gu XY, Yin TX, Yu LY, Zheng JY 等 2026 Aug 27 置信度 0.82
• The importance of classifying central hypopneas: a call to action.
  Obstructive and central sleep apnea share pathophysiologic features and often coexist within individual patients. There is general agreement on the criteria for scoring obstructive and central apneas but less guidance and clarity on how and when to classify ob…
  pubmed Ahn AP, Azarbarzin A, Badr MS, Berry R 等 2026 Aug 27 置信度 0.82
• Nyctanthes arbor-tristis attenuates hyperglycemia: an integrated experimental and computational investigation.
  Nyctanthes arbor-tristis Linn. (Oleaceae) is traditionally used for treating metabolic and inflammatory conditions. This investigation aimed to evaluate the antidiabetic potential of the ethanolic leaf extract of N. arbor-tristis through integrated phytochemic…
  pubmed Singh BR, Yadav JP, Dwivedi AR, Singh AK 等 2026 Aug 27 置信度 0.82
• Postoperative CT-derived spleen volumetry for recurrence risk stratification after curative-intent surgery for hepatic alveolar echinococcosis.
  To evaluate automated CT-derived spleen volumetry as an opportunistic imaging biomarker for postoperative risk stratification in patients with surgically treated hepatic alveolar echinococcosis (AE) and to compare its prognostic performance with clinical and l…
  pubmed Endrös L, Schneider J, Martignoni M, Brückner C 等 2026 Aug 27 置信度 0.82
• Quorum-quenching enzymes as next-generation antibiofilm therapeutics: mechanisms, applications, and future perspectives.
  Quorum sensing (QS) is a form of cell-to-cell communication in bacteria which regulates the activities of biofilm formation, virulence, motility, sporulation and antimicrobial resistance. The growing prevalence of multidrug-resistant pathogens complicates the …
  pubmed Malik HN, Kumar P, Pandit S, Ray S 2026 Aug 27 置信度 0.82
• Neuroimmunology of Oral Cancer: Tumor Progression, Systemic Inflammation, and Neural Circuit Dysfunction from the Cerebellum to the Frontal Cortex.
  Oral cancer, predominantly oral squamous cell carcinoma, ranks among the ten most common malignancies worldwide and carries a disproportionate burden across South and South-East Asia, where tobacco, betel quid, areca nut, and alcohol use remain widespread. Alt…
  pubmed Ahmad I, Kanchon MR, Mim TJ, Rahman MF 等 2026 Aug 27 置信度 0.82
• Emerging Myostatin and Metabolic Hormone Pathway Modulators in Cardiometabolic Disease: Mechanisms, Evidence, and Therapeutic Potential.
  Cardiometabolic disease comprises obesity, type 2 diabetes, heart failure, and sarcopenic obesity, which share interconnected mechanisms including muscle wasting, metabolic dysfunction, fibrosis, mitochondrial impairment, and chronic inflammation. Current ther…
  pubmed Ahad A, Hullon D, Akhavan M, Oskouyan Z 2026 Aug 27 置信度 0.82
• Structure-based discovery of diphenylpyrazines as disruptors of the Skp2-Cks1 protein-protein interaction: computational insights and biochemical validation.
  The Skp2-Cks1 protein-protein interaction is essential for recognition of phosphorylated p27 and contributes to SCF Skp2 -mediated ubiquitination, making this interface an attractive but challenging target for anticancer drug discovery. In this study, we appli…
  pubmed Kamel EM, Allam AA, Rudayni HA, Othman SI 等 2026 Aug 27 置信度 0.82
• Characterizing the molecular mechanisms underlying aluminium-induced disruptions in neuronal survival pathways.
  Aluminium, an omnipresent environmental pollutant, has been recognized for its neurotoxic effects, particularly its ability to promote neuronal death. More research evidence links aluminium exposure to death through molecular mechanisms. This review delves int…
  pubmed Sravya K, Rao A, Harshitha P, Parithathvi A 等 2026 Aug 27 置信度 0.82
• Macrophage programming in systemic sclerosis: Niches, networks, and translational horizons.
  Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by immune dysregulation, microvascular injury, and progressive fibrosis. Among the immune populations implicated in SSc, macrophages are increasingly recognized as context-dependent par…
  pubmed Luo H, Hu D 2026 Aug 27 置信度 0.82
• Systematic analysis of network-driven adaptive resistance to CDK4/6 and oestrogen receptor inhibition using meta-dynamic network modelling.
  Drug resistance inevitably emerges during the treatment of cancer by targeted therapy. Adaptive resistance is a major form of drug resistance, wherein the rewiring of protein signalling networks in response to drug perturbation allows drug-targeted protein act…
  pubmed Hart A, Shin SY, Nguyen LK 2026 Aug 27 置信度 0.82
• A hERG blocker facilitates K+ channel current by promoting pore opening while blocking.
  Many drugs that block voltage-gated K+ channels encoded by the human ether-à-go-go-related gene (hERG) can cause long QT syndrome and life-threatening cardiac arrhythmias, yet the molecular mechanisms that determine this risk remain unclear. A process tha…
  pubmed Docken SS, Marquis MJ, Ngo K, Wada Y 等 2026 Nov 2 置信度 0.82
• Expert nurses vs. ChatGPT for postoperative lumbar disk nursing care.
  The aim of this study was to compare ChatGPT-4-generated responses with expert nurse opinions regarding nursing care after lumbar disk surgery and to assess the adequacy of these responses in supporting nursing knowledge and practice.
  pubmed Gokcen Gokalp M, Calıskan T, Karalar BC 2026 Sep 置信度 0.82
• Finetuning Foundation Models for Temporal Clinical Transcriptomics Data.
  Timeseries clinical transcriptomic datasets offer the opportunity to gain insights into the dynamics of disease mechanisms/treatment responses. However, their utility in uncovering temporal patterns is often limited by high noise levels and small sample sizes.…
  pubmed Mathur S, Kagan A, Passban P, Mattoo H 等 2026 Aug 27 置信度 0.82
• Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist.
  LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical…
  pubmed Wang Y, Zhao J, Zou F, Jiang W 等 2026 Oct 置信度 0.82
• Targeting Airway Remodeling in Severe Asthma: Is There a Window of Opportunity for Biologic Therapy Predicting Effects Using Causal Artificial Intelligence?
  Airway remodeling is increasingly recognized as a major determinant of asthma progression, fixed airflow limitation, and long-term morbidity, particularly in severe disease. Although biologic therapies have transformed outcomes by reducing exacerbations and sy…
  pubmed Gangemi S, Manti S, Virchow JC, Canonica GW 2026 Aug 27 置信度 0.82
• Practical and positive uses of AI in STEM education: taming the AI tiger.
  From website searches and social media to financial services and health services, artificial intelligence (AI) is common in our daily lives. Such an encompassing presence is also apparent in education. All fields, including education, must identify regulations…
  pubmed Crowther GJ, Paustian TD, Parks ST 2026 Aug 27 置信度 0.82
• Artificial Intelligence Chatbots and Large Language Models for Traumatic Dental Injury Management and Decision Support: A Systematic Review With Function-Based Narrative Synthesis and Exploratory Meta-Analysis.
  Traumatic dental injuries require rapid, accurate, and context-sensitive decisions, particularly during emergencies such as tooth avulsion, luxation injuries, and trauma involving the primary dentition. Artificial intelligence (AI) chatbots and large language …
  pubmed Ardila CM, Pineda-Vélez E, Díaz-Laclaustra AI 2026 Aug 27 置信度 0.82
• Coordinated topoisomerase function shapes the fluoroquinolone response of Chlamydia trachomatis.
  DNA supercoiling is essential for the developmental cycle of Chlamydia trachomatis , yet its role in shaping antibiotic responses remains poorly understood. We investigated how the fluoroquinolone moxifloxacin (Mox), a potent DNA gyrase inhibitor, affects C. t…
  pubmed Terrebonne A, Diggs C, Ouellette SP, Gao L 等 2026 Aug 27 置信度 0.82
• Deformation-Adaptive Hybrid Triboelectric-Piezoelectric Nanogenerator for Wearable Muscle Monitoring and Human-Machine Interaction.
  Wearable systems for real-time and long-term musculoskeletal monitoring are increasingly required as shoulder-neck disorders and upper-arm injuries become more prevalent in aging and sedentary populations. However, achieving stable signal acquisition under com…
  pubmed Huang SM, Hou AL, Murti BT, Chen CC 等 2026 Aug 27 置信度 0.82
• Putting the human at the core of human-in-the-loop optimization: integrating clinical expertise and human capacities in exoskeleton learning. An interdisciplinary perspective paper.
  This interdisciplinary perspective aims to identify key limitations in current Human-in-the-Loop Optimization (HILO) approaches for lower-limb exoskeletons (LLEs) and to propose a shift toward more human-centred optimization.
  pubmed Beckwée D, Filtjens B, Claeys R, Lambranzi C 等 2026 Aug 27 置信度 0.82
• Bioabsorbable pin versus kirschner wire fixation in the salter innominate osteotomy for the treatment of developmental dysplasia of the hip.
  PurposeTo evaluate the clinical and radiological effects of bio-pin versus Kirschner wire (K-wire) fixation in Salter innominate osteotomy (SIO) for developmental dysplasia of the hip (DDH).MethodsThis retrospective comparative study included patients aged 1-5…
  pubmed Sarı AS, Dere Kİ, Gültekin MZ, Doğar F 等 2026 May-Aug 置信度 0.82
• A whole-animal phenotypic drug screen identifies suppressors of atherogenic lipoproteins.
  Lipoproteins are essential for lipid transport in all bilaterians. A single Apolipoprotein B (ApoB) molecule is the inseparable structural scaffold of each ApoB-containing lipoprotein (B-lps), which are responsible for transporting lipids to peripheral tissues…
  pubmed Kelpsch DJ, Zhang L, Thierer JH, Rivera Cruz AG 等 2026 Aug 27 置信度 0.82
• Recent advances in smart nanosensors and IoT-based systems for real-time diagnostic monitoring.
  The integration of smart nanosensor systems with artificial intelligence (AI) and the Internet of Things (IoT) is transforming diagnostic monitoring in biomedical, environmental, and industrial applications. These advancements facilitate real-time data acquisi…
  pubmed Omiyale BO, Ogbeyemi A, Odeyemi J, Ashraf MA 等 2026 Aug 27 置信度 0.82
• Synthonpedia: a sustainable and unbiased paradigm for the democratization of retrosynthetic knowledge.
  Existing retrosynthesis AI often inherits literature popularity bias. We introduce Synthonpedia, an open-access, community-driven platform redefining synthetic planning through human-machine cooperation. Using connectivity-based "radical synthons", it streamli…
  pubmed Zanella S, Brusa A, Carlone A 2026 Aug 27 置信度 0.82
• Artificial Intelligence Meets Micro/Nanorobotics.
  Microrobots and nanorobots are a developing technology, which evolved from simple "motoric" motion-capable micro/nanomachines to physical machine intelligence capable of communicating with each other using chemical or physical signals. Meanwhile, artificial in…
  pubmed Yurtsever FM, Ramakrishnan MC, Ross IK, Zelinka I 等 2026 Aug 27 置信度 0.82
• A Fair Energy Comparison of Spiking and Artificial Neural Networks on a General-Purpose Microcontroller.
  Energy efficiency is a key constraint for deploying machine learning models on resource-limited internet of things (IoT) and edge devices. Spiking Neural Networks (SNNs) are often proposed as an energy-efficient alternative to conventional Artificial Neural Ne…
  pubmed Hansert J, Gechter F, Offermann P 2026 Aug 27 置信度 0.82
• Photocorrosion, Protection, and Predictive Design in Solar Water Splitting.
  Photoelectrochemical (PEC) technology is a promising pathway for cost-effective, renewable, and clean fuel production from sunlight and water, addressing critical global energy demands. Despite extensive efforts, the major challenges, including unsatisfactory …
  pubmed Shin SW, Kamble GU, Ghorpade UV, Kang DH 等 2026 Aug 27 置信度 0.82
• POPKI: Modeling Surprise in a Physically-Grounded Joint Inference of Observation, Preference, and Knowledge.
  People naturally take into account others' limited perceptual access when attributing mental states such as preferences and knowledge. This ability is central to intuitive psychology, and even infants recognize when others have only partial observability. Unde…
  pubmed Chen H, Chung K, Bhandwaldar A, Tenenbaum JB 等 2026 置信度 0.82
• Artificial Intelligence in Nuclear Medicine (2015-2025): Clinical Applications, Regulatory Governance, and Pharmacotherapeutic Implications.
  Artificial intelligence (AI) is becoming increasingly relevant in nuclear medicine, particularly in applications that depend on quantitative image analysis, image reconstruction, acquisition optimization, and clinical decision support. This critical narrative …
  pubmed Alpizar-Rojas M, Jaromirski-Segura H, Herrera-Jiménez LG, Castro-Gamboa JA 等 2026 Jul 置信度 0.82
• MMSE-CDR-SB residual as an exploratory indicator of deviation from an Alzheimer's disease-typical cognitive-functional pattern.
  In clinical practice, patients with Alzheimer's disease (AD) often present with cognitive and functional profiles that diverge from what is expected. We tested whether the Mini-Mental State Examination Clinical Dementia Rating Sum of Boxes (MMSE-CDR-SB) residu…
  pubmed Mounié A, Sato K, Nakashima S, Kurihara M 等 2026 Jul-Sep 置信度 0.82
• Stabilizing Iodine in Pyrochlore: Toward New Nuclear Waste Forms.
  The long-term immobilization of iodine-129, a key radionuclide in nuclear waste, remains a major challenge for sustainable nuclear energy. Pyrochlore ceramics, which can be integrated into glass-ceramic waste forms, are widely recognized for their chemical dur…
  pubmed Xu X, Han G, Li T, Hu J 等 2026 Aug 24 置信度 0.82
• Synchronized Chromatin Reorganization as a Key Biomarker in Anesthetic Effects on Plants.
  Anesthesia produces a reversible loss of responsiveness in animals by suppressing neuronal excitability and large-scale network integration, yet its effects on non-neuronal systems remain poorly defined. Plants lack neurons but possess excitable membranes, ele…
  pubmed Chandra S, Mukherjee B, Salam A, Anjum F 等 2026 Aug 24 置信度 0.82
• Long-acting growth hormone therapy in paediatric growth hormone deficiency: reduced treatment burden and unproven motivation-related neuroendocrine effects.
  Long-acting growth hormone (LAGH) formulations represent an important therapeutic advance in the management of growth hormone deficiency (GHD) because they reduce injection frequency and treatment burden and may improve adherence and patient-reported experienc…
  pubmed Gaudino R, Antoniazzi F, Zaffanello M, Pietrobelli A 等 2026 置信度 0.82
• Hydrogel microneedles functioning in pathological surroundings: where soft materials overcome hard scars.
  Pathological scarring is a manifestation of abnormal skin wound healing characterized by fibrosis, resulting from excessive fibroblast activation and abnormal deposition of the extracellular matrix, Currently, the main treatment options, such as corticosteroid…
  pubmed Lei K, Xu Z, Gong D, Wang W 等 2026 Oct 置信度 0.82
• Diagnostic Accuracy of Artificial Intelligence Models for Detecting Odontogenic Keratocytes on CBCT Imaging: A Systematic Review and Meta-Analysis.
  Differentiating odontogenic keratocyst (OKC) from other radiolucent jaw lesions like ameloblastoma is clinically important but radiographically difficult. Recent advances in artificial intelligence (AI) show promise for enhancing diagnosis using cone-beam comp…
  pubmed Shoorgashti R, Lesan S, Ehsani SS, Yazdanfar A 2026 置信度 0.82
• A Two-Stage Hybrid Feature Selection and Ensemble Learning Framework With Explainable AI for Accurate PCOS Prediction.
  Polycystic ovary syndrome (PCOS) is the most prevalent endocrine ailment impacting women of reproductive age, distinguished by ongoing imbalances of hormones that lead to the growth of various ovarian cysts alongside other health issues. Infrequent or delayed …
  pubmed Efty MRH, Rohman MN, Uddin KMM, Rahman MM 等 2026 Sep 置信度 0.82
• Toward autonomous artificial intelligence agents in sports science: a modular framework for development, validation, and implementation.
  Despite widespread artificial intelligence (AI) adoption in sports science for predictive analytics, current systems operate as passive tools requiring continuous human monitoring and intervention at every decision point. Autonomous AI agent systems capable of…
  pubmed Dergaa I, Barbaria S, Dhahbi W, Zmijewski P 等 2026 Jan 置信度 0.82
• Evolution of artificial intelligence and machine learning in DILI toxicogenomics: from descriptive profiling to mechanistic insights.
  Drug-induced liver injury (DILI) is a critical safety issue in drug development, characterized by its idiosyncratic nature, complex mechanisms, and poor predictability in standard preclinical models. High-dimensional omics strategies, particularly toxicogenomi…
  pubmed Rahman MS, Chen M 2026 置信度 0.82
• Association between cardiorespiratory fitness and risk of incident venous thromboembolism: a prospective cohort study.
  Venous thromboembolism (VTE) is a leading cardiovascular disease with substantial burden, yet the association between cardiorespiratory fitness (CRF) and VTE risk remains inconclusive.
  pubmed Zhou H, Zhang R, Jiang Z, Guo Y 等 2026 Jul 置信度 0.82
• Multi-omics-driven precision medicine.
  Precision medicine is increasingly constrained not by a lack of molecular data but by the absence of frameworks that can translate multidimensional biological information into actionable clinical decisions. Multi-omics-driven precision medicine (MODPM) address…
  pubmed Li H, Zhao Z, Zhang Y, Ma Y 等 2026 Aug 25 置信度 0.82
• Oxidative Arene Ring-Opening of Benzylic Alcohols.
  Arene ring-opening (ARO) reaction via C-C bond cleavage remains a formidable challenge due to the exceptional thermodynamic stability of aromatic frameworks. Inspired by enzymatic lignin degradation in nature, we report an oxidative strategy that enables arene…
  pubmed Zhu MH, Cheng Z, Shen WJ, Huang Y 等 2026 Aug 24 置信度 0.82
• TCM-CoT-RAG: a chain-of-thought enhanced retrieval-augmented generation system for clinical decision support in Traditional Chinese Medicine rheumatology.
  Traditional Chinese Medicine (TCM) rheumatology presents unique challenges for AI-assisted clinical decision support, as the diagnostic process relies heavily on tacit knowledge and individualized reasoning. While Large Language Models (LLMs) have shown promis…
  pubmed Fan B, Fang Y, Wang Z, Ma F 2026 置信度 0.82
• The FAD-Dependent Monooxygenase Albo65 Mediates Self-Resistance in Albofungin Biosynthesis.
  The production of specialized small molecules in microorganisms often involves self-resistance mechanisms to prevent autotoxicity. Albofungins belong to the xanthone-containing aromatic polyketides with potent antimicrobial activities. However, its self-resist…
  pubmed Liu Z, Huang C, Xu H, Zhu L 等 2026 Aug 24 置信度 0.82
• Direct Access to the Simplest N‑Substituted Pyrroles from Furans Enabled by Tailored Photocatalysts.
  N -Methylpyrroles are important motifs in pharmaceuticals and biologically relevant compounds, yet their synthesis commonly relies on direct N -methylation of N-H pyrroles, a process often limited by the instability of pyrrole and the use of toxic alkylating r…
  pubmed Byeon H, Hong H, Lee DH, Park Y 等 2026 Aug 24 置信度 0.82
• Spatiotemporal and Digital Electrochemiluminescence Imaging for Intelligent Quantitative Biosensing.
  Electrochemiluminescence (ECL) imaging has progressed from a sensitive-intensity-based detection method to a powerful analytical platform capable of resolving biological and chemical heterogeneity at the single-entity level. This review maps the evolution of E…
  pubmed Zheng Y, Xiao J, Eticha T, Bešlić D 等 2026 Aug 24 置信度 0.82
• Changes in ethics and transparency reporting in dental journal articles between 2021 and 2025: a full-text cross-journal analysis.
  Explicit reporting of research ethics and transparency practices is increasingly emphasized in biomedical publishing, but whether recent changes have occurred uniformly across reporting domains remains unclear.
  pubmed Better H, Asbi T, Chaushu G, Better K 等 2026 置信度 0.82
• Opportunistic osteoporosis screening using multiphase abdominal CT: reliable proximal femur BMD assessment with AI-assisted segmentation.
  To evaluate the agreement and classification concordance of artificial intelligence (AI)-assisted proximal femur bone mineral density (BMD) assessment using multiphase contrast-enhanced abdominal computed tomography (CT), with unenhanced CT-derived quantitativ…
  pubmed Lin F, Xu J, Chen Y, Chen J 等 2026 置信度 0.82
• Artificial Intelligence and Machine Learning for Identifying Social Determinants of Health in Low-Income Populations Within United States Health Systems: A Scoping Review.
  Low-income populations in the United States experience disproportionate exposure to adverse social conditions. This scoping review examined artificial intelligence (AI) and machine learning (ML) approaches used in United States health systems to identify finan…
  pubmed Razzano AV 2026 Sep 置信度 0.82
• Empowering AI assisted clinical drug development: tactics to address data bias, the digital divide and missing patient populations through AI and digital solutions.
  The use of AI methodologies in drug development holds great potential to expedite clinical trials by helping to identify patients most likely to respond favorably to a given medication. To fully harness the benefits of such algorithmic approaches to precision …
  pubmed Papanicolaou D, Perdikeas S, Jones GB 2026 置信度 0.82
• BCG overexpressing Ag85B reprograms host immune response through coordinated transcriptional networks.
  Antigen 85B (Ag85B), an immunodominant protein secreted by Mycobacterium tuberculosis (Mtb), induces robust T-cell-mediated immunity in host cells. Previous studies have demonstrated that recombinant BCG strains overexpressing Ag85B (BCG85B) confer significant…
  pubmed Chauhan V, Kumar R, Veerapandian R, Ramos EI 等 2026 置信度 0.82
• From bench to bedside: experimental pharmacology approaches to overcome bioavailability, stability, and translational barriers of bioactive peptides from natural sources.
  Bioactive peptides derived from natural sources (marine organisms, plants, microbes, and fermented foods) exhibit potent antimicrobial, antihypertensive, antioxidant, and anticancer activities. However, their clinical translation is severely hindered by poor o…
  pubmed Hamadou M, Mishra SK, Abubakar AM, Başaran B 等 2026 置信度 0.82
• Artificial intelligence research in school leadership and management: a text mining-based computational literature review and future directions.
  As artificial intelligence (AI) becomes increasingly embedded in school leadership and management literature, it is important to understand not only which themes are emerging, but also how coherent, mature, and distinct these themes have become. To address thi…
  pubmed Karaköse T, Kaptan O, Kılıç GN, Kocabaş İ 等 2026 置信度 0.82
• Efficacy, safety, and PD-L1-defined outcomes of neoadjuvant immune checkpoint inhibitors in early-stage triple-negative breast cancer: a systematic review and meta-analysis.
  Neoadjuvant immune checkpoint inhibitors combined with chemotherapy improve pathological complete response in early-stage triple-negative breast cancer, but the consistency of benefit, role of PD-L1 expression, and immune-related toxicity remain clinically rel…
  pubmed Ma C, Teoh HK, Qiu D, Zhang Y 等 2026 置信度 0.82
• Responsible workplace data governance and organizational performance: evidence from Chinese listed firms.
  Listed firms increasingly embed analytics, automated processing, algorithmic recommendations, and data flows into work, so data governance shapes how employees and managers experience authority, accountability, privacy, and fairness. This creates an urgent ten…
  pubmed Chen L 2026 置信度 0.82
• Comparative efficacy and safety of IL-23 p19 monoclonal antibodies for plaque psoriasis: a bayesian network meta-analysis of randomized controlled trials.
  To compare the efficacy and safety of IL-23 p19 monoclonal antibodies for moderate-to-severe plaque psoriasis.
  pubmed Xin T, Sun S, Liu Y 2026 置信度 0.82
• The impact and evolution of environmental/occupational, behavioural, and metabolic risk factors on CVD burdens in the Asia-Pacific region from 1990 to 2023: a secondary analysis of the Global Burden of Disease Study 2023.
  Understanding epidemiological trends of the cardiovascular risk factors is integral in designing effective countermeasures in tackling cardiovascular diseases (CVD) in the Asia-Pacific. The study aims to examine the cardiovascular risk factor burden in the Asi…
  pubmed Chew NWS, Chen Y, Cader FA, Chong B 等 2026 Sep 置信度 0.82
• Multimodal DeepSurv model with SHAP-based interpretation for predicting local failure in patients with brain metastases undergoing hypofractionated stereotactic radiotherapy.
  Local Progression-Free Survival (LPFS) is an important clinical endpoint following hypofractionated stereotactic radiotherapy (HSRT) for brain metastases (BMs). However, accurate prediction of local failure risk remains challenging because conventional clinica…
  pubmed Jin L, Zhao Q, Xiao Y, Hu Y 等 2026 置信度 0.82
• Artificial intelligence in preoperative diagnosis of thyroid nodules: a bibliometric analysis.
  To explore the current research progress and trends in the application of artificial intelligence (AI) for preoperative diagnosis of thyroid nodules (TN), and to identify the key research directions through bibliometric analysis.
  pubmed Wu W, Xu Y, Wang H, Han Y 等 2026 置信度 0.82
• Multiplex functional connectome graph transformer for cognitive vulnerability in dialysis-treated chronic kidney disease.
  Chronic kidney disease (CKD) requiring maintenance dialysis is accompanied by cognitive vulnerability and distributed brain-network dysfunction. This study evaluated whether complementary resting-state functional magnetic resonance imaging (rs-fMRI) connectome…
  pubmed Zhai J, Pang J, Lei X, Yan K 等 2026 置信度 0.82
• Digital and AI-assisted approaches across the preeclampsia care pathway: a scoping review.
  To map peer-reviewed evidence across four linked functions of digital and AI-assisted preeclampsia care-risk prediction, patient education, remote blood pressure monitoring, and clinician-directed escalation-and determine whether these functions have been eval…
  pubmed Emilia O, Susaldi S, Agustini Y, Dhamayanti M 等 2026 Aug 置信度 0.82
• Addicted to AI? Prevalence and psychological drivers of generative AI dependency among pre-service teachers.
  Generative artificial intelligence (GenAI) has become embedded in higher education, raising concerns about students' behavioral dependency on these tools. Focusing on pre-service teachers-who will shape how a future generation learns to use AI-we asked how pre…
  pubmed Jiang B, Wang Z 2026 置信度 0.82
• Effect of a robotic insole-type active assist device on horizontal ground reaction force and center-of-pressure stability during stepping in patients with medial knee osteoarthritis.
  An insole-type active assist device has been developed as a robotic system to dynamically correct ankle alignment at heel contact in patients with medial knee osteoarthritis. Although our previous feasibility study demonstrated that the device could be safely …
  pubmed Itami T, Aoki T, Akiyama H 2026 置信度 0.82
• From comparative oncology to AI-enabled precision medicine: translational biomodels for triple-negative breast cancer.
  Triple-negative breast cancer (TNBC), defined by the absence of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 expression or amplification, comprises a biologically heterogeneous group of tumors with aggressive clinical …
  pubmed Collares TV, Seixas FK, Pessoa C, Dagli MLZ 2026 置信度 0.82
• Enhancing IoT botnet detection with explainable ensemble learning.
  Internet of Things (IoT) botnet detection faces significant challenges due to the growing intricacy and decreased transparency of Machine Learning (ML) models.
  pubmed Joseph L, M S, M V 2026 置信度 0.82
• Deployment of Artificial Intelligence in Clinical Oral Pathology: Evidence Summary and Implementation Gaps.
  Whole-slide imaging (WSI) has shifted pathology toward digital workflows, creating the foundation for applying artificial intelligence (AI) to diagnostic tasks. This review summarises validated AI applications in diagnostic pathology, with an emphasis on clini…
  pubmed Shazia Fathima JH, Raghavelu Narendran M, Quadri MSA, Vinothkumar TS 等 2026 置信度 0.82
• Preface to 'advancing uncertainty quantification in artificial intelligence systems using conformal prediction'.
  As artificial intelligence (AI) systems are being widely deployed in safety-critical and high-stakes applications (e.g. medical diagnosis, autonomous vehicles, financial risk assessment), there is a growing demand for providing reliable and trustworthy machine…
  pubmed Nguyen KA, Barber RF, Copley V, Gammerman A 等 2026 Aug 27 置信度 0.82
• Uncertainty-aware large language models: a scoping review of conformal prediction methods.
  In recent years, there has been growing interest in applying conformal prediction (CP) to large language models (LLMs) across diverse domains to enhance the trustworthiness of their predictions. However, the literature still lacks a comprehensive survey of thi…
  pubmed Ashby AE, Nguyen KA, Luo Z 2026 Aug 27 置信度 0.82
• Uncertainty quantification in train delay prediction with conformal prediction.
  Predicting train delays is crucial for railway operations and passenger experience, but point predictions fail to capture uncertainty, limiting their use in risk-aware decisions. Existing uncertainty quantification (UQ) methods often rely on unverifiable assum…
  pubmed Luo R, Su X, Nguyen KA 2026 Aug 27 置信度 0.82
• Synthetic data assurance with conformal prediction.
  In this paper, we apply the methods of conformal prediction to the task of synthetic data assurance using images augmented with synthetic weather effects, and examine their fidelity and diversity with respect to both clear weather and adverse weather real imag…
  pubmed Copley V, Hiett B 2026 Aug 27 置信度 0.82
• Uncertainty quantification using conformal prediction for mesh-based simulations.
  Machine learning surrogates for computational fluid dynamics (CFD) achieve substantial speedups but lack uncertainty quantification (UQ). We develop a post hoc conformal prediction (CP) framework that wraps any trained graph neural network (GNN) surrogate to p…
  pubmed Mabtoul S, Ali I, Ho SS 2026 Aug 27 置信度 0.82
• Avoiding the "Desert of the Real": Preserving Evidence-Based Nursing in the Age of AI.
  A discussion of the implications of generative artificial intelligence (AI) evidence synthesis for evidence-based practice (EBP) among nurses responsible for primary literature appraisal, guideline development, and evidence translation into clinical policy.
  pubmed Azama KA, Nishikawa J 2026 Aug 27 置信度 0.82
• Rehab or not rehab: artificial intelligence helps humans identify rehabilitation Cochrane systematic reviews.
  Rehabilitation is a core component of health systems worldwide, yet its conceptual boundaries remain heterogeneous and difficult to operationalize in research and evidence synthesis. Different classification systems have been proposed, including the pragmatic …
  pubmed Cordani C, Campagner A, Del Furia MJ, Kiekens C 等 2026 Aug 27 置信度 0.82
• De Novo Design of a Protein Binder to Probe Gas Channel and Enhance the Oxygen Tolerance of [NiFe]-Hydrogenase.
  [NiFe]-Hydrogenases display remarkable catalytic efficiency for H 2 production and oxidation but are sensitive to O 2 , which severely restricts their biotechnological applications. The identities and functional relevance of gas channels leading to the buried …
  pubmed Sun X, Xiao Q, Zhang N, Li W 等 2026 Aug 26 置信度 0.82
• Applications of Artificial Intelligence Technologies in Nursing for Noncommunicable Chronic Diseases: A Scoping Review.
  Noncommunicable chronic diseases (NCDs) account for approximately 41 million deaths each year and 74% of global deaths. Artificial intelligence (AI) is increasingly used for risk prediction, monitoring, and decision support in chronic disease care, but its nur…
  pubmed Miao S, Zhang Z, Bao C 2026 置信度 0.82
• Liquid Storage and Cryopreservation of Ram Semen: Storage-Associated Damage and the Role of Non-Enzymatic Antioxidants.
  The successful use of Assisted Reproductive Technologies (ARTs) such as artificial insemination (AI) in small ruminants and other mammals depends on many factors, the most important of which is the quality of the semen used. The liquid storage and cryopreserva…
  pubmed Sohail T, Tharwat M, Shaukat A, Nassar N 等 2026 Aug 17 置信度 0.82
• Therapeutic Monoclonal Antibodies as Advanced Therapies for Companion Animals: Species Adaptation, Fc Biology, Clinical Translation, and Future Platforms.
  Monoclonal antibodies are emerging as advanced therapies in companion-animal medicine, with approved or clinically evaluated applications in canine and feline osteoarthritis pain, canine atopic dermatitis, and selected infectious-disease and oncological settin…
  pubmed Fu Y, Guo Z, Wang H 2026 Aug 3 置信度 0.82
• Development of a Competitive Chemiluminescent Enzyme Immunoassay Based on Recombinant FMDV VP2 Protein for Rapid and Simultaneous Detection of Antibodies Against Foot-and-Mouth Disease Virus Serotypes O and A.
  Timely detection of specific antibodies against foot-and-mouth disease virus (FMDV) is critical to effective prevention and control of the disease. In this study, we developed a competitive chemiluminescent enzyme immunoassay (cCLEIA) based on recombinant FMDV…
  pubmed Bian S, Yue Z, Zhou L, Ai J 等 2026 Aug 2 置信度 0.82
• Trends in Tick-Borne Virus Ecology: Vector Incrimination, Focal Distribution, and Reservoir Associations.
  Ticks are prominent hosts for many viruses that are pathogenic to humans on almost every continent. Despite the documented historical association of ticks with viral disease in humans, clinical case reports are low, likely due to under-recognition of these pat…
  pubmed Lange RE, Dupuis AP 2nd, Ciota AT 2026 Aug 21 置信度 0.82
• Advances in Molecular Techniques for Detecting Sweet Potato (Ipomoea batatas (L.) Lam) Viruses: A Comprehensive Review.
  Sweet potato ( Ipomoea batatas (L.) Lam) is an important global food crop, but its production is threatened by numerous viral pathogens. More than 30 RNA and DNA viruses have been reported worldwide, making rapid and accurate detection essential for disease ma…
  pubmed Azad MAK, Ibnat N, Chowdhury SS, Huq S 等 2026 Aug 18 置信度 0.82
• Simulating the Transmission of Rift Valley Fever Virus via Raw Milk Consumption in Inter-Epidemic Periods.
  Rift Valley fever virus (RVFV) is a zoonotic, vector-borne disease affecting livestock and humans. The consumption of raw unpasteurized milk has been epidemiologically linked to RVFV exposure in humans and recognized as a potentially important non-vector route…
  pubmed Buyukcangaz E, Tariq A, Peña-García VH, Bisanzio D 等 2026 Aug 13 置信度 0.82
• Metabolomic Analysis of Lytic KSHV Infection: Induced Host Nucleotide Metabolism Is Required for Infectious Virus Production.
  Kaposi's Sarcoma Herpesvirus (KSHV) is the etiological agent of Kaposi's Sarcoma (KS), which induces metabolic stress in infected host cells. KSHV reprograms host metabolic pathways for efficient viral replication and infectious virion production. Here, we rep…
  pubmed Hisam F, Winn EA, Mukherjee S, Price SE 等 2026 Aug 11 置信度 0.82
• Cross-Reactivity of 15 JEV Antigen-Directed Rabbit Antisera with Three Clinically Important JEV Serogroup Members: WNV, MVEV, and SLEV.
  Japanese encephalitis virus (JEV), the prototype member of the JEV serogroup within the genus Orthoflavivirus (family Flaviviridae ), is closely related to West Nile virus (WNV), Murray Valley encephalitis virus (MVEV), and St. Louis encephalitis virus (SLEV).…
  pubmed Yun SI, Lee YM 2026 Aug 10 置信度 0.82
• FluEvoFormer: A Structure-Guided Generative Foundation Model for Prospective Influenza Antigenic Evolution and Vaccine Strain Selection.
  Seasonal influenza vaccine strain selection remains challenging because circulating viruses may drift after vaccine recommendations are made. This study presents FluEvoFormer, a structure-guided generative foundation model for prospective influenza antigenic e…
  pubmed Agarwal P, Yogarayan S, Sayeed MS 2026 Aug 1 置信度 0.82
• SARS-CoV-2 Surveillance in Free-Ranging Wildlife in New England and Virginia, United States, 2022-2025.
  Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected a wide range of animal species, including wildlife. Although SARS-CoV-2 infection has been widely reported in wildlife, particularly in white-tailed deer (WT…
  pubmed Sanogo IN, Puryear WB, Simulynas AF, Cox E 等 2026 Jul 29 置信度 0.82
• Real-Time Imaging of HIV-1 Protease Activation and Substrate Cleavage in Single Virions Assembling on the Plasma Membrane.
  The timing of HIV-1 protease (PR) activation and the determinants of orderly Gag and Gag-Pol polyprotein cleavage, leading to structural maturation of virions, are not well-understood. Here, we employed total internal reflection microscopy to visualize PR acti…
  pubmed Li Y, Singh SP, Marin M, Zhan AL 等 2026 Jul 25 置信度 0.82
• Target-Oriented Screening of Traditional Chinese Medicine Potential Inhibitors Against African Swine Fever Virus dUTPase and Preliminary Evaluation of Enzymatic Activity Effects.
  African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious disease that has brought severe economic losses to the global swine industry. ASFV dUTPase is a key enzyme modulating viral nucleotide metabolism and genome stability…
  pubmed Zhao M, Dai X, Tang H, Wu C 等 2026 Jul 23 置信度 0.82
• Design and Evaluation of an Edge AI-Enabled Low-Power Magnetic Sensor for Real-Time Road Traffic Monitoring.
  Road traffic surveys require sensing systems that can be deployed rapidly without modifying the road surface or requiring a permanent power connection. This paper presents the design, embedded implementation, and evaluation of a low-power roadside magnetic sen…
  pubmed Hodoň M, Šarafín P, Formanek L, Kociánová A 2026 Aug 21 置信度 0.82
• A Priority-Aware Multi-Agent Reinforcement Learning Framework for Collaborative Intelligent Sensing in Social IoT.
  Collaborative intelligent sensing in the Social Internet of Things (Social IoT) relies on distributed AI-enabled sensors to support complementary information sharing, multimodal perception, and real-time autonomous decision-making. Under high-load conditions, …
  pubmed Zhu J 2026 Aug 21 置信度 0.82
• Dynamic LoRA Fine-Tuning of DINOv3 for Multi-Component Pasture Biomass Estimation.
  Accurate estimation of pasture biomass components from imagery is essential for sustainable grazing management and precision agriculture. Conventional methods such as destructive harvesting, rising plate meters, and remote sensing are limited by scalability, r…
  pubmed Sen S, Dhankhar N, Bayat A 2026 Aug 20 置信度 0.82
• A Dual-Camera Edge Sensing Framework with Zone-Aware Multi-Object Tracking for Sensorless Smart Vending Cabinets.
  Top-loading smart vending cabinets require precise transaction-level product detection under strict hardware and deployment constraints. In this paper, "sensorless" refers specifically to the absence of auxiliary product-level sensing hardware, such as RFID ta…
  pubmed Buriboev AS, Rajabov F, Buriboev S, Allanyazov R 等 2026 Aug 17 置信度 0.82
• AI-Aquatica-RS: A Modular Python Framework for Reproducible Fusion of Remote-Sensing-Derived Spectral Indices and In Situ Water-Quality Observations.
  Remote-sensing-derived spectral indices and in situ measurements provide complementary information for aquatic monitoring, but their practical integration is complicated by asynchronous observations, heterogeneous tables, missing acquisitions, and non-reproduc…
  pubmed Miller T, Durlik I 2026 Aug 14 置信度 0.82
• Sensor-Based and AI-Driven Ergonomic Seated Posture Detection for Workplace Risk Prevention.
  Work-related musculoskeletal disorders (WMSDs) remain one of the most prevalent occupational health problems worldwide. To prevent the development of these WMSDs in an office space, a chair designed for office monitoring capable of accurately identifying ten r…
  pubmed Teixeira T, Barbosa G, Areias B, Guerra A 等 2026 Aug 13 置信度 0.82