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• Truth, tone, and trust: integrating an AI exercise to foster responsible science communication in a graduate biomedical science course.
  As generative AI becomes a standard fixture in graduate education, the pedagogical challenge has shifted from detection to integration. This article describes a curriculum intervention developed for Anatomy of Scientific Error, a graduate-level course on scien…
  europepmc 2026 置信度 0.80
• Effectiveness of an AI-augmented teacher feedback model in improving medical students' clinical documentation skills: a retrospective cohort study.
  Clinical documentation is central to evaluating medical students' clinical competence. However, traditional teacher feedback is often inefficient, inconsistent, or delayed. This study evaluates the effectiveness of an AI-augmented teacher feedback model in imp…
  pubmed Hu S, Du F, Fang C, Zheng X 等 2026 置信度 0.82
• H3K18 lactylation drives CD8<sup>+</sup> T cell exclusion and anti-PD-1 resistance in hepatocellular carcinoma.
  Glycolytic metabolism promotes an immunosuppressive microenvironment in HCC, but its role in immunotherapy resistance is unclear. Patients with HCC with high 18 F-FDG uptake on PET/CT show reduced anti-PD-1 response. High glycolysis-driven H3K18la levels corre…
  europepmc 2026 置信度 0.80
• Functional role of the diadenylate cyclase gene cdaA in stress responses of the dairy starter Streptococcus thermophilus.
  Streptococcus thermophilus is a key dairy starter culture widely used in the production of yogurt and cheese, where its robustness in stress adaptation and growth performance is critical for industrial fermentation efficiency. Cyclic di-AMP (c-di-AMP) is a key…
  europepmc 2026 置信度 0.80
• Enhancing the sustainability of cultural identity in science curricula through artificial intelligence as an innovative educational approach.
  This study investigates the role of AI as an innovative educational approach in promoting the sustainability of cultural identity within science curricula. To achieve this aim, a qualitative research design was employed, using semi-structured interviews and cl…
  europepmc 2026 置信度 0.80
• A CNN-based liver ultrasound plane recognition system with multimodal large language model-generated interpretable feedback.
  Objective To construct a hybrid artificial intelligence (AI) pipeline that combines a convolutional neural network (CNN) for image recognition with a multimodal large language model (MLLM) for textual interpretation, and to evaluate its application value in id…
  europepmc 2026 置信度 0.80
• AI in scientific publishing: Slower, worse, and more expensive.
  There’s a saying in the management world, popularized by NASA administrator Daniel Goldin in the 1990s, that the goal of technological improvements is to make products faster, better, and cheaper. Although this strategy had some success in the aerospace indust…
  europepmc H. Holden Thorp 2026 置信度 0.80
• Teacher-regulated generative AI support, student agency, and perceived learning gains in higher education: the moderating role of perceived fairness.
  Introduction Generative artificial intelligence is increasingly used in higher education, yet its educational value depends not only on technological access but also on how its use is pedagogically regulated. This study examined how teacher-regulated generativ…
  europepmc 2026 置信度 0.80
• Interbacterial AI-2 signaling orchestrates chemotaxis, attachment, and antimicrobial peptide resistance to promote <i>Salmonella</i> colonization.
  Quorum sensing enables bacteria to coordinate collective behaviors crucial for survival and infection. Here, we show that Salmonella Typhimurium employs LuxS/autoinducer-2 (AI-2) signaling to regulate multiple stages of pathogenesis. AI-2 functions as a chemoa…
  europepmc 2026 置信度 0.80
• Bismuth Incorporation Induced Low-Frequency Phonon Enhancing the Kinetics and Stability of Cathodes for Sodium-Ion Batteries.
  Rapid capacity fading, along with severe challenges in the fast-charging process, such as anomalous migration of transition metals (TMs) in-plane and out-of-plane, lattice stress, and microcrack formation, leads to poor cycle performance, which seriously hinde…
  europepmc 2026 置信度 0.80
• A Single OLED With Hybrid Synaptic Plasticity Enabling In Situ Neuromorphic Processing and Visualization.
  As the core interface for human-computer interaction, multitask intelligent display systems face increasingly stringent demands regarding precision and functional integration. However, in existing architectures, light-emitting units only act as passive display…
  europepmc 2026 置信度 0.80
• Signaling mechanisms and dynamics governing the myocardial-epicardial fate switch during human cardiogenesis.
  The signaling mechanisms and developmental dynamics that govern the divergence of myocardial and epicardial lineages during human heart development remain poorly understood. Here, we developed a human pluripotent stem cell-based cardiac development model and e…
  europepmc 2026 置信度 0.80
• Perceptions of Artificial Intelligence in Gynecologic Oncology Education: Insights from a Qualitative Study Using Semi-Structured Interviews.
  Training in gynecologic oncology requires mastery of complex decision making and technically demanding procedures, yet opportunities for repetitive practice are often limited by case volume, patient-safety considerations, and unequal access to expert supervisi…
  europepmc 2026 置信度 0.80
• Chinese expert concern and consensus on applications of artificial intelligence in clinical cancer imaging.
  Artificial intelligence (AI) demonstrates potential throughout the cancer care continuum, with evidence supporting its application in medical imaging for detection, staging, treatment planning, and prognostic evaluation. However, clinical translation is hinder…
  europepmc 2026 置信度 0.80
• The AI-native health science institution innovation theater vs. structural redesign.
  Academic health institutions face a new constraint: cognitive labor. Many adopt AI through additive initiatives that risk becoming "innovation theater"-visible activity without structural change. We argue this reflects a mismatch between rapid AI advances and …
  europepmc 2026 置信度 0.80
• SpatialFormer: universal spatial representation learning from subcellular molecular to multicellular landscapes.
  Understanding gene spatial expression and the organization of multicellular systems is vital for disease diagnosis and studying biological processes. However, existing models often struggle to integrate gene expression data with cellular spatial information ef…
  europepmc 2026 置信度 0.80
• FAIR Data Standards for AI in Plant Biology: Current Practice and Case Studies.
  Artificial Intelligence (AI) has become a central analytical approach in plant science, supporting prediction, pattern discovery, and integration across molecular, phenotypic, and environmental data. While methodological advances have been rapid, progress is i…
  europepmc 2026 置信度 0.80
• Prompt Framing and Evidence Requirement for AI-Generated Educational Responses in Dental Education: Experimental Study.
  Large language models are increasingly used in health professions education; however, the role of prompt design in shaping their outputs remains poorly understood in clinical training contexts. In dentistry, where information presentation, perceived credibilit…
  pubmed Hung M, Ward C, Cohen O, Marx J 等 2026 Aug 6 置信度 0.82
• The Digital Evolution of the Medical Black Bag: Environmental Scan With Trend Analysis and Horizon Scanning.
  The medical black bag is synonymous with physicians, especially general practitioners, who are expected to be ready to provide care across settings. The content of the devices they use will likely expand due to the proliferation of digital tools. As portable d…
  pubmed Katonai G, Arvai N, Mesko B 2026 Aug 6 置信度 0.82
• Trust-Centered Design and Feasibility Evaluation of an AI-Enabled Conversational Health Tool for Sexual and Reproductive Health Among Rural Young Adults: Protocol for a Mixed Methods Study.
  Young adults aged 18 to 25 years in rural communities face barriers to sexual and reproductive health (SRH) information, including clinician shortages, clinic closures, and privacy concerns in close-knit communities. Many rely on online sources of varying qual…
  pubmed Brennan K 2026 Aug 6 置信度 0.82
• Mortality Research With Artificial Intelligence Tools: Applying Language Models to the National Violent Death Reporting System Suicide Narratives, 2003-2023.
  Suicide deaths in the United States have increased for a generation with no current evidence of meaningful decline. With advances in data collection and accumulation, suicide prevention research has started utilizing artificial intelligence (AI) tools, predomi…
  pubmed Blosnich JR, Ranjit J, Swayamdipta S 2026 Aug 6 置信度 0.82
• The NLRP3 inflammasome in the pathogenesis of erectile dysfunction: mechanistic insights and therapeutic potential.
  The NLRP3 inflammasome is a critical innate immune sensor that drives inflammatory responses and has been implicated in various chronic diseases. However, its specific role in erectile dysfunction (ED) remains incompletely understood, and the evidence supporti…
  pubmed Yin F, Chen H, Tu H, Zhong H 等 2026 Jun 30 置信度 0.82
• Sparsity is all you need: rethinking biologically informed neural networks.
  Biologically informed neural networks are increasingly adopted in bioinformatics under the premise that embedding biological knowledge into model architectures yields more accurate and interpretable predictions. This approach has driven a growing literature of…
  pubmed Caranzano I, Pancotti C, Rollo C, Sartori F 等 2026 Jul 3 置信度 0.82
• AI-Based Learning Experiences of Nursing Students: A Qualitative Study.
  Global nursing courses are rapidly attempting to utilise large language models (LLMs), and generative AI such as ChatGPT now traverses the traditional classroom-clinical divide.
  pubmed Miao J, Chen HL, Peng XY, Shi L 等 2026 Aug 置信度 0.82
• Antioxidant and Antihypertensive Activities of Ficus exasperata Vahl Leaves: Integrated In Vitro Evaluation and In Silico Multi-Target Mechanistic Insights.
  Hypertension (HTN) remains a major global health challenge and a leading cause of cardiovascular morbidity. The limitations of conventional antihypertensive therapies, including high cost and side effects, highlight the need for alternative interventions. This…
  pubmed Fajana E, Esiaba I 2026 Aug 置信度 0.82
• Salicifoliosides A and B: A Pair of Furan Glycoside Isomers From Chimonanthus salicifolius and Their Modulation of the Functions of Caco-2 Cells.
  Chimonanthus salicifolius has traditionally been used for the treatment of gastrointestinal disorders. In this study, a systematic phytochemical investigation of this plant was conducted, leading to the isolation and identification of two previously undescribe…
  pubmed Yang HZ, Wu YW, Shangguan WJ, Min R 等 2026 Aug 置信度 0.82
• Phytochemical Profiling and Biological Evaluation of Anthyllis henoniana Organs: Integrated In Vitro and Molecular Docking Insights Into Antioxidant, Anti-Inflammatory, and Cytotoxic Potential.
  Anthyllis henoniana leaves and flowers were subjected to fractionated extraction using cyclohexane (CYHA), dichloromethane (DCM), ethyl acetate (EtOAc) and methanol (MeOH). The leaves-MeOH extract showed the highest yield and total polyphenol contents (TPC) co…
  pubmed Jaber S, Rahmani R, Bouajila J, Debouba M 2026 Aug 置信度 0.82
• AI-designed viral genomes.
  The generation of functional viral genomes has urgent biosafety and biosecurity implications.
  pubmed Inglesby TV, Hanke MS 2026 Aug 6 置信度 0.82
• The next Turing tests: Reimagining conceptions and measures of AI.
  New approaches to evaluating progress of AI should be built around diversity, partnership, and systemicity.
  pubmed Hernandez-Orallo J, Collins KM, Cheke L, Weidinger L 等 2026 Aug 6 置信度 0.82
• How should India approach AI?
  In an unstable geopolitical environment, countries are looking to secure access to artificial intelligence (AI) capabilities, which are seen as essential to economic growth, scientific research, and national security. Few have placed sovereignty as squarely at…
  pubmed Kapur A, Narayanan A 2026 Aug 6 置信度 0.82
• A multi-stage stacking framework for accurate and interpretable life expectancy modeling.
  Accurate life-expectancy estimation is critical for evidence-based health policy, monitoring Sustainable Development Goal 3 (SDG 3), and guiding global resource allocation. Existing machine-learning approaches typically provide point predictions with limited i…
  pubmed Chinthaginjala R, Tera SP, Natha P, Srinivasulu A 等 2026 置信度 0.82
• A bacterial fatty acid enzyme hijacks nucleic acid-sensing Toll-like receptor signaling.
  Innate immune recognition shapes infection outcomes by linking microbial detection to host defense. Although pattern recognition receptors are classified by the ligands they detect (lipids, peptidoglycans, or nucleic acids) cross-talk between these pathways is…
  pubmed Lathram WA, Lages PC, Radka CD 2026 Aug 11 置信度 0.82
• AI-driven PROTAC design overcomes oncogenic resilience by eliminating the CLIP1-LTK fusion protein.
  The discovery of CAP-Gly domain-containing linker protein 1(CLIP1)-Leukocyte tyrosine kinase (LTK) as an oncogenic fusion reveals a unique dependency not only on LTK kinase activity but also on CLIP1-mediated multimerization, a noncatalytic function that drive…
  pubmed Chen S, Duan H, Zhong S, Ge J 等 2026 Aug 11 置信度 0.82
• Validation of an Automated Brief Frailty Screening Tool Using Interactive Voice Response in Community-Dwelling Older Adults.
  Frailty is a multidimensional condition linked to adverse outcomes in older adults, yet most screening tools rely on in-person assessment, limiting scalability. Automated approaches are needed for large-scale screening.
  pubmed Ji S, Jang GY, Lee E, Baek JY 等 2026 Aug 6 置信度 0.82
• The use of artificial intelligence models for interpretation and triage of clinical referral letters to acute and specialist care pathways: Protocol for a systematic review.
  Clinical referral letters direct patients into acute, urgent, and specialist care pathways, but their triage is typically manual, heterogeneous, and resource intensive, contributing to waiting-list pressure and potential patient harm. Artificial intelligence (…
  pubmed Foley J, Hession E, Umana E, Boland F 2026 置信度 0.82
• Exploring the influencing factors of academic doctoral students' academic innovation behavior in the context of generative artificial intelligence: Self-determination theory and motivation-opportunity-ability perspectives.
  Although generative artificial intelligence (GenAI) has increasingly reshaped academic research practices, existing studies have mainly examined its technical affordances or isolated factors such as AI literacy. Less attention has been paid to how different ty…
  pubmed Liu Y, Zhang M, Peng Y 2026 置信度 0.82
• Barriers, adoption patterns, and determinants of artificial intelligence use among health sciences students in Palestine.
  Artificial intelligence (AI) is increasingly integrated into healthcare education worldwide, yet disparities in access, training, and institutional readiness remain evident, particularly in low-resource and conflict-affected settings. Understanding how health …
  pubmed Alqaissi N, Qtait M 2026 Aug 置信度 0.82
• GanCtrl: A Generative AI Approach to Derive Study-Aligned Synthetic Controls for Reducing Concurrent Control Animal Use.
  Minimizing the use of animals as concurrent controls in in vivo studies directly supports the 3Rs principles of Replacement, Reduction, and Refinement. Current virtual control group (VCG) approaches primarily rely on historical control data, but their utility …
  pubmed Chandra M, Chen X, Li T, Tong W 2026 Aug 6 置信度 0.82
• Large language models can supplement the assessment of clinical high risk for psychosis.
  Capturing psychosis risk before illness onset is an ongoing challenge for psychosis-spectrum studies. Natural language processing (NLP) tools can harness information embedded in the notes generated during clinical interviews to obtain more objective markers of…
  pubmed Alliende LM, Voigt R, Hoffman M, Strauss GP 等 2026 Aug 6 置信度 0.82
• Integrative analysis of TCGA data identifies hsa-miR-200a as a breast cancer-associated microRNA biomarker with exploratory serum validation.
  Breast cancer is a biologically heterogeneous disease, and reliable non-invasive biomarkers are needed to improve early detection and clinical risk stratification. MicroRNAs (miRNAs) represent promising diagnostic candidates due to their regulatory roles in tu…
  pubmed Park K, Kim EY, Lee EJ, Nam H 等 2026 Aug 6 置信度 0.82
• Mitochondrial metabolism and PD-1 blockade: mechanisms and therapeutic opportunities in cancer immunotherapy.
  The development of immune checkpoint inhibitors (ICIs) targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway has brought about a breakthrough in cancer treatment; nevertheless, therapeutic resistance remains a significa…
  pubmed Dizaji Asl K, Kalarestaghi H, Rafat A, Bahramloo M 等 2026 Aug 6 置信度 0.82
• Mathematical Modeling of HDV RNA, HBV DNA, and HBsAg Dynamics During Lonafarnib-Based Therapy: Insights from the LOWR HDV-1 Study.
  Lonafarnib (LNF) is an investigational drug targeting hepatitis delta virus (HDV) but not hepatitis B virus (HBV), providing a unique opportunity to model HDV kinetics and how changes in HDV affect HBV. We performed a detailed kinetic analysis and developed a …
  pubmed Mhlanga A, Shekhtman L, Zakh R, Duehren S 等 2026 Aug 6 置信度 0.82
• P-VERIFY: Real-World Comparative Overall Survival and Progression-Free Survival of CDK4/6 Inhibitors Plus an Aromatase Inhibitor in Patients with HR+/HER2- Metastatic Breast Cancer in the USA-A Vodcast.
  To date, there have been no head-to-head randomized controlled trial data comparing cyclin-dependent kinase 4/6 (CDK4/6) inhibitors in patients with HR+/HER2- metastatic breast cancer (mBC), and most prior real-world comparative effectiveness studies have been…
  pubmed Rugo HS, Ryan JC 2026 Aug 6 置信度 0.82
• Water use efficiency in cereal crops: stomatal, hydraulic, biochemical mechanisms, and translational strategies for improvement.
  Water use efficiency in cereal crops is governed by molecular processes operating across biological scales that are connected imperfectly and non-linearly, from guard cell ion channel gating to canopy evapotranspiration. Despite the global urgency of improving…
  pubmed Ali B, Hafeez A, Imin N 2026 Aug 6 置信度 0.82
• Effects of insomnia-focused psychological and behavioral interventions on depressive symptoms in children and adolescents: a systematic review and meta-analysis.
  Psychological and behavioral interventions for insomnia are increasingly recognized as promising approaches not only to improve sleep but also to influence mental health outcomes in children and adolescents. This systematic review and meta-analysis examined th…
  pubmed Galling B, Wu J, Oberstadt A, Dück A 等 2026 Aug 6 置信度 0.82
• Comparative evaluation of large language models and clinicians in real-world glaucoma clinical reasoning.
  Clinical decision-making in glaucoma is complex and requires integration of heterogeneous information, including patient history, examination findings, and risk stratification. While artificial intelligence (AI) has shown strong performance in image-based opht…
  pubmed Yin H, Shen L, Cai H, Wu W 等 2026 Aug 6 置信度 0.82
• Machine learning-enabled prediction of ART pregnancy outcomes: a systematic review and meta-analysis.
  To systematically evaluate the diagnostic accuracy and methodological quality of machine learning (ML) prediction models for pregnancy outcomes after assisted reproductive technology (ART).
  pubmed Li B, Liu H, Yu F, Xiong M 等 2026 Aug 6 置信度 0.82
• AI-generated patient information leaflets for oral anticoagulants: quality, usability, readability, and reproducibility compared with FDA-referenced materials.
  Oral anticoagulants are frequently associated with preventable hospital admissions, and patient education is essential to their safe and effective use. Patients increasingly use large language models (LLMs) for medication information, yet few studies have comp…
  pubmed Khan MA, Maazuddin M, Al Abdullah A, Sultan I 等 2026 Aug 6 置信度 0.82
• Streamlining Cancer Reporting: CAP eCC Template Integration and Data Management.
  Cancer affects over 1,000 active-duty military personnel annually, directly undermining force readiness. To address this challenge, the Department of Defense, Department of Veterans Affairs (VA), and the National Cancer Institute established the Applied Proteo…
  pubmed Seagal A, Deyarmin B, Murtha KN, Fantacone-Campbell JL 等 2026 Aug 1 置信度 0.82
• An Artificial Intelligence Copilot for First Response Medicine.
  First responders in emergency medicine often work in austere conditions where expert consultation is limited, communication networks are unreliable, and rapid decision-making is essential. In these environments, procedural precision directly impacts patient ou…
  pubmed Zhuo Y, Radman M, Zhang E, Pachpande A 等 2026 Aug 1 置信度 0.82
• Baseline Corpus Construction and Proof-of-concept Experiments for AI/ML-Enabled Syndromic Surveillance.
  The variability in subjective symptom descriptions challenges the early detection of novel diseases and syndromes. This lack of consistent terminology complicates the recognition of emerging health threats, such as Gulf War Illness (GWI), a multisystem conditi…
  pubmed Diaz LM, Ling C, Beaudoin ME 2026 Aug 1 置信度 0.82
• Overcoming Clinical Validation Challenges for an In Vitro Diagnostic Biodosimetry Test.
  In the aftermath of a nuclear detonation or other mass-casualty radiological event, thousands to millions of people may be exposed to high levels of radiation. Effective triage tools are needed to identify those with potentially life-threatening exposure requi…
  pubmed Damer KS, Smith CL, Mahnke RC, Kowalski RJ 等 2026 Aug 1 置信度 0.82
• TO-207 Mitigates Radiation-Induced Hematopoietic Injury in a Murine Model of Lethal Total-Body Irradiation.
  Ionizing radiation exposure can cause acute radiation syndrome (ARS) with life-threatening multi-organ damage. Although several hematopoietic growth factors are FDA-approved as radiation countermeasures, alternative strategies that target inflammatory mechanis…
  pubmed Cui W, Hull L, Rothstein A, Wang L 等 2026 Aug 1 置信度 0.82
• Artificial Intelligence/Machine Learning-Driven cfDNA Methylation Blood Test for Early Cancer Detection in Military Personnel With Environmental Toxin Exposure.
  Military personnel face heightened cancer risks from exposure to burn-pit emissions, per- and polyfluoroalkyl substances (PFAS), jet fuel, and radiation. Veterans show elevated malignancy rates, and active-duty personnel remain vulnerable because of ongoing op…
  pubmed Subharam M, Koehler R, Sreedhar T 2026 Aug 1 置信度 0.82
• Artificial intelligence and spiritual health in primary care: lowering barriers without losing connection.
  pubmed Whitehead IO 2026 Jul 31 置信度 0.82
• Heart Failure Outcome Prediction Using Artificial Intelligence-enabled Coronary Artery Calcium CT Chamber Volumetry Compared to American Heart Association PREVENT and the Agatston Score for Heart Failure Risk Stratification.
  Purpose To evaluate whether artificial intelligence (AI)-derived chamber volumetry from coronary artery calcium (CAC) CT improves heart failure (HF) risk prediction. Materials and Methods This retrospective study included asymptomatic patients without known ca…
  pubmed Momin E, Barr J, Gershon G, Zhou B 等 2026 Aug 置信度 0.82
• AI-Driven Multiomics Biomarkers for Precision Oncology: Navigating the Translational Gap and Regulatory Hurdles.
  The discussion on precision oncology integrates multiomics technologies and artificial intelligence, specifically addressing biomarker discovery and personalized therapeutic strategies. In this way, clinical translation and multiomics biomarkers are reconstruc…
  pubmed Havelikar U, Shinde A, Mhaismale H, Pawar P 等 2026 Aug 6 置信度 0.82
• A review of radiotherapy linear accelerator quality control techniques.
  This study provides a review of recent publications on different quality control (QC) techniques for radiotherapy linear accelerators (linacs). QC in radiotherapy is essential to ensure patient safety, deliver optimal quality treatments, monitor equipment perf…
  pubmed Tassano-Smith E, Palmer AL, Polak W, Nisbet A 2026 Aug 6 置信度 0.82
• Soluble protein analog selection engine (SPASE): An automated AI-powered server to improve protein engineering workflows.
  The design of proteins with desired biophysical properties, such as high solubility and low aggregation propensity, is crucial for various biotechnological and biomedical applications. While deep learning-based methods like ProteinMPNN have shown remarkable su…
  pubmed Larda ST, Paré A, Doucet N 2026 Sep 置信度 0.82
• Pathogen-phage geomapping to overcome resistance.
  The rise of antibiotic resistance has renewed interest in bacteriophages as therapeutic alternatives. However, coevolution of phage and bacteria will naturally give rise to phage-resistant pathogens, complicating phage therapy efforts. A critical bottleneck in…
  pubmed Do C, Salazar KC, Chang JD, Clark JR 等 2026 Aug 6 置信度 0.82
• AI-powered robotic assistive technologies in rehabilitation: global trends, ethical dimensions and human-centred futures.
  The aim of this study is to examine global research trends, the conceptual framework and emerging research themes relating to artificial intelligence (AI)-supported robotic assistive technologies in the field of rehabilitation, through bibliometric and themati…
  pubmed Uyanık G, Bulut A, Serin MK 2026 Aug 6 置信度 0.82
• Using AI-ECG to Stratify Long-Term Mortality Risk and Prognosis in TAVR Patients.
  Long-term mortality remains unsatisfactorily high after transcatheter aortic valve replacement (TAVR). Conventional risk models are limited in capturing subclinical electrophysiological alterations associated with poor prognosis, which can be identified on rou…
  pubmed Shi W, Yan P, Zhu Q, Pu G 等 2026 Aug 4 置信度 0.82
• The complexity cliff in natural product discovery: why full automation remains elusive and the case for collaborative intelligence.
  Covering: 1992 to 2025Natural products contribute to roughly half of FDA-approved small-molecule drugs, yet their discovery has remained surprisingly resistant to the automation that has reshaped synthetic medicinal chemistry. In this review, we examine why. W…
  pubmed Lin R, Zhou C, Wu R, Wang Y 等 2026 Aug 6 置信度 0.82
• Calcium Phosphate Nanoparticle Delivery of siTRIB3 Inhibits EMT and Stemness in NSCLC.
  TRIB3 is upregulated in non-small cell lung cancer (NSCLC) and associates with worse survival, yet targeted therapeutics remain lacking. Calcium phosphate (CaP) nanoparticles offer biocompatible, serum-stable delivery for siRNA therapy. Here, we developed CaP …
  pubmed Wu Y, Song J, He S, Zhang J 等 2026 置信度 0.82
• Engineering Biology in an Age of Convergence: Evolving Research Leadership at the AI-SynBio-Robotics Frontier.
  Artificial intelligence (AI), engineering biology (often called synthetic biology), automation, and RNA therapeutics are rapidly converging into integrated discovery and translation platforms in which computational design, automated experimentation, and biolog…
  pubmed McLennan RKJ, Kitney R, Pretorius IS 2026 Jan-Dec 置信度 0.82
• Antibody-Drug Conjugates and Peptide-Drug Conjugates: Current Understandings and Future Perspectives.
  Antibody-drug conjugates (ADCs) and peptide-drug conjugates (PDCs) are modular targeted therapeutics in which molecular recognition is coupled with controlled payload delivery. Owing to their high specificity and precision, they have been regarded as a transfo…
  pubmed Zheng R, Li S, Zhang Z, Niu M 等 2026 Aug 置信度 0.82
• Strategies used by international sports federations in the field of technology.
  This research explores how international sports federations (IFs) use new technologies to enhance at their events. It overviews the digital initiatives and tools deployed to improve in-person and remote experiences. The study analyses two main questions: which…
  pubmed Desbordes M, Rywalski T 2026 置信度 0.82
• Artificial intelligence in neurosurgery: A patent bibliometric analysis of the Lens database.
  Artificial intelligence (AI) has rapidly expanded across neurosurgery with applications in neuroimaging analysis, surgical planning, intraoperative guidance, neuromodulation, and outcome prediction. Bibliometric analyses of scholarly works cited by patents pro…
  pubmed Rosenberg J, Tellinghusen B, Gould J, Patel S 等 2026 置信度 0.82
• miR-15a-5p outperforms anti-VEGF drug in ocular neovascularization by providing dual anti-angiogenic and neuroprotective effects.
  Pathological ocular neovascularization is a major driver of vision-threatening retinal diseases. This study aimed to investigate the role and therapeutic potential of miR-15a-5p in ocular neovascular disorders.
  pubmed Zhang H, Yu X, Yang F, Yu R 等 2026 置信度 0.82
• NeuDiff Agent: a governed AI workflow for single-crystal neutron crystallography.
  Large-scale facilities increasingly face analysis and reporting latency as a limiting step in scientific throughput, particularly for structural studies that require iterative reduction, integration, refinement and validation. To improve the time to result and…
  pubmed Xiao Z, Zhang L, Zhang G, Wang X 2026 Aug 1 置信度 0.82
• Multi-organ AI endophenotypes chart the heterogeneity of brain, eye and heart pan-disease.
  Disease heterogeneity and commonality pose significant challenges to precision medicine, as traditional approaches frequently focus on single disease entities and overlook shared mechanisms across conditions. Inspired by pan-cancer and multi-organ research, we…
  pubmed MULTI Consortium, Boquet-Pujadas A, Anagnostakis F, Yang Z 等 2026 Feb 置信度 0.82
• Antiglycation of Insulin by Selected Six Bioactive Peanut Sprout Stilbenoids and Demonstration of Methylglyoxal-Mediated Biphasic Insulin Glycation by O-Phenylenediamine Derivatization.
  Protecting insulin molecules from glycation by the dietary ingredients is critical to alleviate diabetes-associated metabolic complications. Six peanut sprout stilbenoids were selected for antiglycation determination with bovine insulin mediated by methylglyox…
  pubmed Chiu PC, Lin SM, Li YJ, Lo CY 等 2026 Aug 置信度 0.82
• Digital technology-assisted labor support in delivery rooms on maternal pain and anxiety: a systematic review and meta-analysis.
  Labor pain and anxiety are important factors affecting maternal childbirth experience. Digital technology-assisted labor support, such as virtual reality (VR) analgesia and artificial intelligence (AI)-assisted fetal heart rate monitoring interpretation, has g…
  pubmed Zou S, Wang Y, Fu Y 2026 置信度 0.82
• Perspectives on the use and implementation of artificial intelligence in pharmacy education and training: Views of faculty, PharmD students, and pharmacists in Saudi Arabia.
  Artificial intelligence (AI) offers new approaches to addressing challenges in educational learning and teaching processes. This study aims to investigate perspectives on the use and implementation of AI in pharmacy education and training among pharmacy facult…
  pubmed Alsharif AA, Alsaleh N, Alshehri GH, AlRasheed HA 等 2026 Jan-Dec 置信度 0.82
• Lacosamide Use After Traumatic Brain Injury: A Scoping Review.
  Lacosamide (LCM) is a newer antiepileptic drug that enhances slow inactivation of voltage-gated sodium channels and modulates collapsin response mediator protein-2, suggesting potential roles in seizure control and axonal protection after traumatic brain injur…
  pubmed Taniguchi H, Yamada S 2026 Jul 置信度 0.82
• Faculty development and institutional readiness for incorporating AI in health professions education- A narrative review.
  Artificial Intelligence (AI) is presently reshaping higher education in a rapid way, due to the high engagement of students with AI. The study's aim was to explore strategies driving transformation in higher education at large and particularly dental education…
  pubmed Prasad P, Amin M, Sari EF, Annamma LM 等 2026 置信度 0.82
• AI-Driven vision large language framework for pediatric pain assessment.
  Accurate pediatric pain assessment is essential for effective pain management and procedural safety. However, current evaluations largely rely on subjective scales and casual behavioral observations. Although automated pain assessment methods have been propose…
  pubmed Li B, Pang J, Cai Y, Yu J 等 2026 置信度 0.82
• AI-driven discovery of probiotic gene modules and their functional impact in food and health.
  How a probiotic works depends on its genes, its proteins, and the environment it lives in. Current knowledge gaps make it hard to predict how probiotics act in different foods or to find new, useful traits. To address this, we developed a new AI tool that anal…
  pubmed Alshatari S, Ziarno M 2026 置信度 0.82
• AI can write the paper-but whose paper is it?
  pubmed Narayan P 2026 Sep 置信度 0.82
• AI-Enabled Wearable Ultrasound for Noninvasive Central Venous Pressure Monitoring.
  Central venous pressure (CVP) is a key indicator of right ventricular preload, but measurement with a central venous catheter (CVC) is invasive, time-consuming, and unsuitable for bedside monitoring. We developed and clinically evaluated an artificial intellig…
  pubmed Dong L, Zhang X, Li M, Li Y 等 2026 置信度 0.82
• Spatial analysis of the association between convenience store density and the prevalence of obesity and hypertension in South Korea.
  The growing demand for quick and convenient meals has altered eating behaviors and contributed to the rise in convenience stores in South Korea. Convenience stores often provide energy-dense, nutrient-poor foods, which may contribute to unhealthy eating behavi…
  pubmed Yun A, Jung H, Jung G, Kim B 等 2026 置信度 0.82
• The relative age effect among Malaysian university athletes: a cross-sectional survivorship analysis with exploratory AI-based movement screening.
  The relative age effect (RAE) is defined as the overrepresentation of athletes born early in the selection year and is well documented in talent identification. However, whether the selection pressures that produce the RAE leave a detectable biomechanical sign…
  pubmed Moganan H, Sankaravel M, Elumalai G, Thung JS 等 2026 置信度 0.82
• Mitigating environmental public health risks via artificial intelligence: mechanisms and boundary conditions.
  Environmental pollution threatens population health through multiple and overlapping pathways, including gaseous emissions, wastewater discharge, and industrial solid waste. Artificial intelligence (AI) can improve environmental monitoring, energy management, …
  pubmed Qiu Y, Huang S, Deng W, Gary J 2026 置信度 0.82
• Reference Hallucination in AI-Assisted Academic Writing: A Comparative Analysis of ChatGPT, Gemini, and Perplexity in Rotator Cuff Literature.
  This study aimed to compare the reliability of references generated by three different AI-based conversational agents (ChatGPT, Gemini, Perplexity) within the rotator cuff literature.
  pubmed Özbek İC, Bağcıer F 2026 Aug 置信度 0.82
• Bibliometric and visualization analysis of arginine deiminase research from 2006 to 2025: trends, collaboration networks and emerging frontiers.
  Peptidylarginine Deiminase/Protein Arginine Deiminase (PAD/PADI) are a family of enzymes that catalyze protein citrullination, converting arginine residues to citrulline residues in a calcium-dependent manner. The net loss of positive charge of protein citrull…
  pubmed Jiang S, Gan L, Wang Q, Cao G 等 2026 置信度 0.82
• AI applied to Saudi Arabia higher education: systematic literature review-SLR with PRISMA and VOSviewer.
  This study explored the role of artificial intelligence in higher education in Saudi Arabia. It aims to identify trends, key contributors, influential papers, collaborations, and important research areas from January 2022 to February 2026 to guide future resea…
  pubmed Alqurni J 2026 置信度 0.82
• Leveraging machine learning models to forecast pediatric allergic rhinitis exacerbation risk based on environmental exposure data.
  Acute exacerbations of pediatric allergic rhinitis (AR) are difficult to anticipate, and individualized risk tools integrating clinical and environmental data are lacking. We developed an interpretable machine-learning model to predict 90-day AR exacerbation r…
  pubmed Li Z, Huang S, Xia Z 2026 置信度 0.82
• Transforming endoscopic retrograde cholangiopancreatography: the role of artificial intelligence in pre-operative planning, intraoperative navigation, and post-operative risk prediction.
  Endoscopic Retrograde Cholangiopancreatography (ERCP) is a technically demanding procedure for pancreaticobiliary diseases. Artificial intelligence (AI) is transforming ERCP by improving diagnostic accuracy, procedural safety, and postoperative risk prediction…
  pubmed Wang Y, Peng Y, Wang Z, Liu P 等 2026 置信度 0.82
• Analysing open-source protein folding models for nanobody binding prediction.
  Antibody-based therapeutics are a rapidly expanding class of treatments, with over 200 approved candidates and thousands in clinical trials. Computational pre-filtering using protein structure prediction models has the potential to reduce the cost of wet-lab s…
  pubmed Vogt Y, Roßberg R, Habermann J, Kluge P 等 2026 置信度 0.82
• The serial mediating effects of learning motivation and learning engagement on the relationship between gen AI literacy and EFL perceived proficiency among vocational students.
  Generative artificial intelligence (Gen AI) has emerged as a transformative technology in English language education. However, research examining the serial mediating roles of learning motivation and learning engagement in the relationship between Gen AI and v…
  pubmed Zhang R, Talib OB, Liu S, Chen Z 等 2026 置信度 0.82
• An analysis of AI platforms: Can AI provide genetics education?
  With the introduction, free access, and proliferation of various artificial intelligence (AI) in unique platforms, patients have access to more summarized information than ever. Our study aimed to explore the use of AI chatbots to improve patients' understandi…
  pubmed Shin A, Shin R, Ramirez M, Bondre IL 等 2026 Aug 置信度 0.82
• Darunavir and Fosamprenavir Inhibit Zika Virus Replication via Dual Targeting of the Envelope Protein and NS2B-NS3 Protease.
  Zika virus (ZIKV) remains a significant global health concern, underscoring the need for effective antiviral agents. In this study, we evaluated the antiviral activity and mechanisms of the HIV protease inhibitors darunavir (DRV), fosamprenavir (FPV), and ampr…
  pubmed Kan JY, Su HC, Lai HC, Lin YF 等 2026 Aug 置信度 0.82
• Potent Inhibition of Dengue Virus Infection by Synthetic Compound TXD-174 Through Specific Targeting of IL-24.
  Dengue virus (DENV) infection has emerged as a critical global public health challenge, particularly in tropical and subtropical regions, where it continues to cause high morbidity rates and severe disease risks. Given the current lack of specific antiviral th…
  pubmed Han J, Kong W, Guo D, Liu S 等 2026 Aug 置信度 0.82
• Stratification by a polygenic risk score of common variation aids in Alzheimer's disease rare variant discovery.
  We utilized an Alzheimer's disease (AD) polygenic risk score (PRS) to discover associations with novel rare variants (RVs).
  pubmed Olayinka O, Farrell JJ, Zhu C, Khurshid Z 等 2026 Aug 置信度 0.82
• Unified definition of integrated diagnostics: a position statement of the EFLM.
  Integrated diagnostics is an emerging multidisciplinary model of care that integrates traditionally siloed domains, including pathology, radiology, genomics, and laboratory medicine, into a coordinated framework designed to improve diagnostic accuracy, treatme…
  pubmed Lennerz JK, Del Ben F, Stenzinger A, Frauenknecht KBM 等 2026 Aug 7 置信度 0.82
• Genomic Benchmarking Reveals Reduced and Context-Dependent Transferability of AI-Engineered Bxb1 Recombinases for Large-Fragment Genome Writing.
  Programmable large-fragment genome integration using prime-editing-coupled serine integrases, such as PASTE and PASSIGE, remains constrained by the limited activity of wild-type Bxb1 (WT Bxb1) in mammalian cells. Recently, the AI-guided protein engineering fra…
  pubmed Sun YD, Song LJ, Liu B, Cheng CY 等 2026 Aug 6 置信度 0.82
• Fungal biodiversity and oxidative enzymes: nature-based solutions for lignin degradation and circular economy applications.
  Lignin is one of the most abundant yet recalcitrant biopolymers in nature, and its inefficient depolymerization remains a major bottleneck in lignocellulosic biomass valorization and sustainable biorefinery development. Although fungal oxidative enzymes have e…
  pubmed Dutta A, Borang N, Yadav M 2026 Aug 6 置信度 0.82
• Anti-TNF withdrawal or long-term treatment in ulcerative colitis (BIOSTOP): a multicentre open label, randomized controlled trial.
  Anti-tumour necrosis factor (anti-TNF) treatment is effective in ulcerative colitis (UC). Optimal treatment duration is uncertain. This trial studies outcome after anti-TNF withdrawal compared to maintenance treatment in UC.
  pubmed Berset IP, Lerang F, Moum B, Jahnsen J 等 2026 Aug 5 置信度 0.82
• Cognitive biases in AI-assisted medical decision making: A structured review as a primer for veterinary and human pathology.
  Cognitive biases are systematic patterns of error in human thinking. While artificial intelligence (AI)-based decision support systems offer great potential to enhance diagnostic accuracy and efficiency in pathology, collaboration between medical professionals…
  pubmed Rosbach E, Ammeling J, Bertram CA, Riener A 等 2026 Aug 5 置信度 0.82
• RIOK2 Promotes Clear Cell Renal Cell Carcinoma Progression Through Cell Cycle Regulation.
  Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of kidney cancer and is frequently associated with poor clinical outcomes. Ribosome biogenesis, which is upregulated in many malignancies, plays a key role in tumor proliferation. Right open…
  pubmed Shikuma H, Goto K, Shimo A, Hatayama T 等 2026 Aug 置信度 0.82