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• Using graph theory to analyze biological networks
  Understanding complex systems often requires a bottom-up analysis towards a systems biology approach. The need to investigate a system, not only as individual components but as a whole, emerges. This can be done by examining the elementary constituents individ…
  openalex Georgios A. Pavlopoulos, Maria Secrier, Charalampos Moschopoulos, Theodoros Soldatos 等 2011-04-28 置信度 0.72 Computer scienceBiological networkProfiling (computer programming)Theoretical computer scienceGraph
• Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
  Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libr…
  openalex Maxim V. Kuleshov, Matthew R. Jones, Andrew D. Rouillard, Nicolas Fernandez 等 2016-05-03 置信度 0.72 UploadBiologySet (abstract data type)Web serverInterface (matter)
• Thermodynamically Consistent Force Fields for the Assembly of Inorganic, Organic, and Biological Nanostructures: The INTERFACE Force Field
  The complexity of the molecular recognition and assembly of biotic-abiotic interfaces on a scale of 1 to 1000 nm can be understood more effectively using simulation tools along with laboratory instrumentation. We discuss the current capabilities and limitation…
  openalex Hendrik Heinz, Tzu‐Jen Lin, Ratan K. Mishra, Fateme S. Emami 2012-12-31 置信度 0.72 Force field (fiction)van der Waals forceParametrization (atmospheric modeling)BiomoleculeChemical physics
• Using DECIPHER v2.0 to Analyze Big Biological Sequence Data in R
  In recent years, the cost of DNA sequencing has decreased at a rate that has outpaced improvements in memory capacity. It is now common to collect or have access to many gigabytes of biological sequences. This has created an urgent need for approaches that ana…
  openalex S. Wright Erik 2016-01-01 置信度 0.72 DECIPHERSequence (biology)Computational biologyComputer scienceData science
• Co-clustering of biological networks and gene expression data
  MOTIVATION: Large scale gene expression data are often analysed by clustering genes based on gene expression data alone, though a priori knowledge in the form of biological networks is available. The use of this additional information promises to improve explo…
  openalex Daniel Hanisch, Alexander Zien, Ralf Zimmer, Thomas Lengauer 2002-07-01 置信度 0.72 Cluster analysisHierarchical clusteringExpression (computer science)Biological networkComputer science
• Amorphous computing
  ver the next few decades, two emerging technologies-microfabrication and cellular engineering-will make it possible to assemble systems incorporating myriads of informationprocessing units at almost no cost, provided all units need not work correctly and that …
  openalex Harold Abelson, David S. Allen, Daniel Coore, Chris Hanson 等 2000-05-01 置信度 0.72 Library scienceComputer science
• Hardy-Weinberg Equilibrium Testing of Biological Ascertainment for Mendelian Randomization Studies
  Mendelian randomization (MR) permits causal inference between exposures and a disease. It can be compared with randomized controlled trials. Whereas in a randomized controlled trial the randomization occurs at entry into the trial, in MR the randomization occu…
  openalex Santiago Rodrı́guez, Tom R. Gaunt, Ian N. M. Day 2009-01-06 置信度 0.72 Mendelian randomizationMissing dataStatisticsGenotypingHardy–Weinberg principle
• Biologically Rationalized Computing Techniques For Image Processing Applications
  openalex 2017-08-17 置信度 0.72 Image processingComputer scienceImage (mathematics)Digital image processingComputer graphics (images)
• IOBR: Multi-Omics Immuno-Oncology Biological Research to Decode Tumor Microenvironment and Signatures
  Recent advances in next-generation sequencing (NGS) technologies have triggered the rapid accumulation of publicly available multi-omics datasets. The application of integrated omics to explore robust signatures for clinical translation is increasingly emphasi…
  openalex Dongqiang Zeng, Zilan Ye, Rongfang Shen, Guangchuang Yu 等 2021-07-02 置信度 0.72 OmicsComputational biologyComputer scienceBioinformaticsBiology
• Design patterns from biology for distributed computing
  Recent developments in information technology have brought about important changes in distributed computing. New environments such as massively large-scale, wide-area computer networks and mobile ad hoc networks have emerged. Common characteristics of these en…
  openalex Özalp Babaoğlu, Geoffrey Canright, Andreas Deutsch, Gianni A. Di 等 2006-09-01 置信度 0.72 Computer scienceDistributed computingRobustness (evolution)Replication (statistics)Stigmergy
• Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity
  Hydrogel is a type of versatile platform with various biomedical applications after rational structure and functional design that leverages on material engineering to modulate its physicochemical properties (e.g., stiffness, pore size, viscoelasticity, microar…
  openalex Huấn Cao, Lixia Duan, Yan Zhang, Jun Cao 等 2021-12-16 置信度 0.72 Current (fluid)NanotechnologyChemistryMaterials scienceEngineering
• Analysis of Biological Data - A Soft Computing Approach
  openalex 2007-01-01 置信度 0.72 Computer scienceSoft computingArtificial intelligenceArtificial neural network
• HMDB 5.0: the Human Metabolome Database for 2022
  The Human Metabolome Database or HMDB (https://hmdb.ca) has been providing comprehensive reference information about human metabolites and their associated biological, physiological and chemical properties since 2007. Over the past 15 years, the HMDB has grown…
  openalex David S. Wishart, AnChi Guo, Eponine Oler, Fei Wang 等 2021-10-20 置信度 0.72 MetabolomeMetabolomicsIdentification (biology)Computer scienceMetabolite
• Fundamental challenges in mobile computing
  This paper is an answer to the question "What is unique and conceptuntly different about mobile computing?" The paper begins by describing a set of constraints intrinsic to mobile computing, and examining the impact of these constraints on the design of distri…
  openalex Mahadev Satyanarayanan 1996-01-01 置信度 0.72 Computer scienceCitationWorld Wide WebFifteenthMobile device
• Networks of spiking neurons: The third generation of neural network models
  openalex Wolfgang Maass 1997-12-01 置信度 0.72 Artificial neural networkComputer scienceSpiking neural networkNervous system network modelsArtificial intelligence
• Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography
  openalex Fabien Hyafil, Jean‐Christophe Cornily, Jonathan E. Feig, Ronald Gordon 等 2007-04-08 置信度 0.72 Coronary arteriesMedicineFibrous capThrombusLumen (anatomy)
• Guided bone regeneration: materials and biological mechanisms revisited
  Guided bone regeneration (GBR) is commonly used in combination with the installment of titanium implants. The application of a membrane to exclude non-osteogenic tissues from interfering with bone regeneration is a key principle of GBR. Membrane materials poss…
  openalex Ibrahim Elgali, Omar Omar, Christer Dahlin, Peter Thomsen 2017-08-19 置信度 0.72 MembraneRegeneration (biology)Narrative reviewBiocompatible materialBiochemical engineering
• Biological Computing Fundamentals and Futures
  The fields of computing and biology have begun to cross paths in new ways. In this paper a review of the current research in biological computing is presented. Fundamental concepts are introduced and these foundational elements are explored to discuss the poss…
  openalex Balaji Akula, James Cusick 2009-11-09 置信度 0.72 Futures contractComputer scienceData scienceCurrent (fluid)Management science
• Quantum Neural Computing
  openalex Subhash Kak 1995-01-01 置信度 0.72 Quantum computerComputer scienceComputationArtificial neural networkQuantum
• RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning
  The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center for the open-access PDB archive. As wwPDB-designated Archive Keeper, RCSB PDB is also respo…
  openalex S.K. Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich 等 2022-11-02 置信度 0.72 Protein Data Bank (RCSB PDB)Protein Data BankCollaboratoryData curationStructural bioinformatics
• PARAMETER ESTIMATION OF IN SILICO BIOLOGICAL PATHWAYS WITH PARTICLE FILTERING TOWARDS A PETASCALE COMPUTING
  The aim of this paper is to demonstrate the potential power of large-scale particle filtering for the parameter estimations of in silico biological pathways where time course measurements of biochemical reactions are observable. The method of particle filterin…
  openalex Kazuyuki Nakamura, Ryo Yoshida, Masao Nagasaki, Satoru Miyano 等 2008-11-01 置信度 0.72 Petascale computingComputer scienceParticle filterIn silicoEstimation
• Computed structures of core eukaryotic protein complexes
  Deep learning for protein interactions The use of deep learning has revolutionized the field of protein modeling. Humphreys et al . combined this approach with proteome-wide, coevolution-guided protein interaction identification to conduct a large-scale screen…
  openalex Ian R. Humphreys, Jimin Pei, Minkyung Baek, Aditya Krishnakumar 等 2021-11-11 置信度 0.72 Computational biologyProteomeSaccharomyces cerevisiaeEukaryotic cellYeast
• Haralick's Texture Features Computed by GPUs for Biological Applications
  Abstract—This paper presents an approach to speedup the computation of co-occurrence matrices and Haralick texture features, as used for analyzing microscopy images of cells, by general-purpose graphics processing units (GPUs). The sequence of computation step…
  openalex Markus Gipp, Guillermo Marcus, Nathalie Harder, Apichat Suratanee 等 2009-02-01 置信度 0.72 SpeedupComputer scienceComputationGraphicsSoftware
• BMGE (Block Mapping and Gathering with Entropy): a new software for selection of phylogenetic informative regions from multiple sequence alignments
  BACKGROUND: The quality of multiple sequence alignments plays an important role in the accuracy of phylogenetic inference. It has been shown that removing ambiguously aligned regions, but also other sources of bias such as highly variable (saturated) character…
  openalex Alexis Criscuolo, Simonetta Gribaldo 2010-01-01 置信度 0.72 Phylogenetic treeMultiple sequence alignmentBiologyInferenceTrimming
• Features and development of Coot
  Coot is a molecular-graphics application for model building and validation of biological macromolecules. The program displays electron-density maps and atomic models and allows model manipulations such as idealization, real-space refinement, manual rotation/tr…
  openalex Paul Emsley, Bernhard Lohkamp, W. G. Scott, Kevin Cowtan 2010-03-23 置信度 0.72 Computer scienceScripting languageSoftwareInterface (matter)Human–computer interaction
• decoupleR: ensemble of computational methods to infer biological activities from omics data
  Summary: Many methods allow us to extract biological activities from omics data using information from prior knowledge resources, reducing the dimensionality for increased statistical power and better interpretability. Here, we present decoupleR, a Bioconducto…
  openalex Pau Badia-i-Mompel, Jesús Vélez Santiago, Jana M. Braunger, Celina Geiß 等 2022-01-01 置信度 0.72 BioconductorComputer sciencePython (programming language)InterpretabilityLeverage (statistics)
• MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization
  This article describes several features in the MAFFT online service for multiple sequence alignment (MSA). As a result of recent advances in sequencing technologies, huge numbers of biological sequences are available and the need for MSAs with large numbers of…
  openalex Kazutaka Katoh, John Rozewicki, Kazunori Yamada 2017-08-07 置信度 0.72 Sequence (biology)Multiple sequence alignmentComputer scienceVisualizationService (business)
• Biological Computing with Diffusion and Excitable Calcium Stores
  Intracellular signaling often employs excitable stores of calcium coupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gates for computation. We also describe how the …
  openalex H. G. E. Hentschel, Alan Fine, C.S. Pencea, C. Pencea 2004-03-01 置信度 0.72 DiffusionCalciumBiophysicsStatistical physicsComputer science
• Study of biological networks using graph theory
  As an effective modeling, analysis and computational tool, graph theory is widely used in biological mathematics to deal with various biology problems. In the field of microbiology, graph can express the molecular structure, where cell, gene or protein can be …
  openalex Wei Gao, Hualong Wu, Muhammad Kamran Siddiqui, Abdul Qudair Baig 2017-11-14 置信度 0.72 Biological networkTopological indexTheoretical computer scienceGraphVertex (graph theory)
• Cerium oxide nanoparticle: a remarkably versatile rare earth nanomaterial for biological applications
  Cerium oxide nanoparticles (CeONPs) have attracted much attention because they possess multi-enzyme mimetic properties and have been used in bioanalysis, biomedicine, drug delivery, bioscaffold and so on. This review summarizes recent achievements on CeONPs ca…
  openalex Can Xu, Xiaogang Qu 2014-03-01 置信度 0.72 Cerium oxideCeriumNanoparticleMaterials scienceNanotechnology
• Bioinspired bio-voltage memristors
  Memristive devices are promising candidates to emulate biological computing. However, the typical switching voltages (0.2-2 V) in previously described devices are much higher than the amplitude in biological counterparts. Here we demonstrate a type of diffusiv…
  openalex Tianda Fu, Xiaomeng Liu, Hongyan Gao, Joy E. Ward 等 2020-04-20 置信度 0.72 MemristorVoltageNanowireNanotechnologyFunction (biology)
• Biological UV Photoreceptors‐Inspired Sn‐Doped Polycrystalline β ‐Ga 2 O 3 Optoelectronic Synaptic Phototransistor for Neuromorphic Computing
  Abstract In this study, the authors fabricate Sn‐doped 100‐nm thick polycrystalline β ‐Ga 2 O 3 synaptic field‐effect transistors (FETs) emulating optical and electrical spike stimulation. When stimulated by deep ultraviolet (UV) optical spikes or electric vol…
  openalex Youngbin Yoon, Young‐Ki Kim, Wan Sik Hwang, Myunghun Shin 2023-05-05 置信度 0.72 Neuromorphic engineeringMaterials scienceOptoelectronicsSpike-timing-dependent plasticityExcitatory postsynaptic potential
• Computing and applying trust in web-based social networks
  The proliferation of web-based social networks has lead to new innovations in social networking, particularly by allowing users to describe their relationships beyond a basic connection. In this dissertation, I look specifically at trust in web-based social ne…
  openalex Jennifer Golbeck, James Hendler 2005-01-01 置信度 0.72 Computational trustComputer scienceWeb of trustRelevance (law)Social network (sociolinguistics)
• Upper Ocean Carbon Export and the Biological Pump
  openalex Hugh W. Ducklow, Deborah K. Steinberg, Ken O. Buesseler 2001-01-01 置信度 0.72 Biological pumpEnvironmental scienceOceanographyCarbon fibersCarbon cycle
• A Continuous Method to Compute Model Parameters for Soft Biological Materials
  Developing appropriate mathematical models for biological soft tissues such as ligaments, tendons, and menisci is challenging. Stress-strain behavior of these tissues is known to be continuous and characterized by an exponential toe region followed by a linear…
  openalex Martín Tanaka, Charles A. Weisenbach, Mark Carl Miller, Laurel Kuxhaus 2011-06-17 置信度 0.72 Classification of discontinuitiesExponential functionCurve fittingNonlinear systemAlgorithm
• A minimum data set approach to post-mortem computed tomography reporting for anthropological biological profiling
  openalex Alison Brough, Bruno Morgan, Claire Robinson, Sue Black 等 2014-07-18 置信度 0.72 Forensic anthropologyComputed tomographyProfiling (computer programming)Radiological weaponArtificial intelligence
• STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
  Proteins and their functional interactions form the backbone of the cellular machinery. Their connectivity network needs to be considered for the full understanding of biological phenomena, but the available information on protein-protein associations is incom…
  openalex Damian Szklarczyk, Annika L. Gable, David Lyon, Alexander Junge 等 2018-11-16 置信度 0.72 String (physics)KEGGBiologyComputational biologyComputer science
• SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
  To be effective as a drug, a potent molecule must reach its target in the body in sufficient concentration, and stay there in a bioactive form long enough for the expected biologic events to occur. Drug development involves assessment of absorption, distributi…
  openalex Antoine Daina, Olivier Michielin, Vincent Zoete 2017-03-03 置信度 0.72 CheminformaticsADMEDrug discoveryContext (archaeology)Computer science
• Continuous Distributed Representation of Biological Sequences for Deep Proteomics and Genomics
  We introduce a new representation and feature extraction method for biological sequences. Named bio-vectors (BioVec) to refer to biological sequences in general with protein-vectors (ProtVec) for proteins (amino-acid sequences) and gene-vectors (GeneVec) for g…
  openalex Ehsaneddin Asgari, Mohammad R. K. Mofrad 2015-11-10 置信度 0.72 Structural genomicsComputational biologyProtein sequencingProteomicsStructural Classification of Proteins database
• Small-angle scattering: a view on the properties, structures and structural changes of biological macromolecules in solution
  1. Introduction 148 2. Basics of X-ray and neutron scattering 149 2.1 Elastic scattering of electromagnetic radiation by a single electron 149 2.2 Scattering by assemblies of electrons 151 2.3 Anomalous scattering and long wavelengths 153 2.4 Neutron scatterin…
  openalex Michel H. J. Koch, Patrice Vachette, Dmitri I. Svergun 2003-05-01 置信度 0.72 ScatteringMacromoleculeNeutron scatteringBiological small-angle scatteringSpherical harmonics
• Beyond von‐Neumann Computing with Nanoscale Phase‐Change Memory Devices
  Abstract Historically, the application of phase‐change materials and devices has been limited to the provision of non‐volatile memories. Recently, however, the potential has been demonstrated for using phase‐change devices as the basis for new forms of brain‐l…
  openalex C. David Wright, Peiman Hosseini, Jorge A. Vázquez Diosdado 2012-12-12 置信度 0.72 Von Neumann architectureNeuromorphic engineeringComputer scienceRealization (probability)Phase change
• Advances in photonic reservoir computing
  Abstract We review a novel paradigm that has emerged in analogue neuromorphic optical computing. The goal is to implement a reservoir computer in optics, where information is encoded in the intensity and phase of the optical field. Reservoir computing is a bio…
  openalex Guy Van der Sande, Daniel Brunner, Miguel C. Soriano 2017-03-01 置信度 0.72 Reservoir computingNeuromorphic engineeringComputer sciencePhotonicsOptical computing
• Biological Effects and Adaptive Response from Single and Repeated Computed Tomography Scans in Reticulocytes and Bone Marrow of C57BL/6 Mice
  This study investigated the biological effects and adaptive responses induced by single and repeated in vivo computed tomography (CT) scans. We postulated that, through the induction of low-level oxidative stress, repeated low-dose CT scans (20 mGy, 2 days/wee…
  openalex Nghi Phan, Michael De Lisio, Gianni Parise, Douglas R. Boreham 2012-01-30 置信度 0.72 Nuclear medicineIn vivoMedicineApoptosisBone marrow
• Telomere Length as an Indicator of Biological Aging
  Chronological age is the primary determinant of stiffness of central arteries. Increased stiffness is an independent indicator of cardiovascular risk. The aim of this study was to determine whether telomere length, a possible index of biological aging, provide…
  openalex Athanase Bénétos, Koji Okuda, Malika Lajemi, Masayuki Kimura 等 2001-02-01 置信度 0.72 TelomerePulse wave velocityPulse pressureArterial stiffnessBlood pressure
• PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data
  Single-cell RNA sequencing is an increasingly used method to measure gene expression at the single cell level and build cell-type atlases of tissues. Hundreds of single-cell sequencing datasets have already been published. However, studies are frequently depos…
  openalex Oscar Franzén, Li‐Ming Gan, Johan Björkegren 2019-01-01 置信度 0.72 Computer scienceAnnotationCell typeComputational biologyCompendium
• MUTUAL INFORMATION RELEVANCE NETWORKS: FUNCTIONAL GENOMIC CLUSTERING USING PAIRWISE ENTROPY MEASUREMENTS
  Increasing numbers of methodologies are available to find functional genomic clusters in RNA expression data. We describe a technique that computes comprehensive pair-wise mutual information for all genes in such a data set. An association with a high mutual i…
  openalex Atul J. Butte, Isaac S. Kohane 1999-12-01 置信度 0.72 Mutual informationPairwise comparisonRelevance (law)Cluster analysisEntropy (arrow of time)
• On quantum neural computing
  openalex Subhash Kak 1995-03-01 置信度 0.72 Computer scienceQuantum computerArtificial neural networkContext (archaeology)Reductionism
• WGCNA: an R package for weighted correlation network analysis
  BACKGROUND: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method for describing the correlation patterns among genes across microarray samples. We…
  openalex Peter Langfelder, Steve Horvath 2008-12-01 置信度 0.72 Gene co-expression networkR packageComputer scienceSoftwareData mining
• Hybrid Biological-Digital Systems in Artistic and Entertainment Computing
  The authors give an overview of existing incorporations of biological systems for behavior generation within digital systems. The authors investigate digital systems that have artistic and/or entertainment goals, including computer games. The overview conclude…
  openalex Wim van Eck, Maarten H. Lamers 2013-01-17 置信度 0.72 EntertainmentComputer scienceReflection (computer programming)MultimediaState (computer science)
• The interpretation of biological motion
  openalex Donald D. Hoffman, Bruce E. Flinchbaugh 1982-01-01 置信度 0.72 Biological motionMotion (physics)Structure from motionPlanarity testingMotion field
• An Examination of Some Metaphorical Contexts for Biologically Motivated Computing
  Biologically motivated computing seeks to transfer ideas from the biosciences to computer science. In seeking to make transfers it is helpful to be able to appreciate the metaphors which people use. This is because metaphors provide the context through which a…
  openalex Ray Paton, Hyacinth S. Nwana, M. J. R. Shave, Trevor Bench‐Capon 1994-06-01 置信度 0.72 Variety (cybernetics)Computer scienceContext (archaeology)Process (computing)Data science
• Natural computing for mechanical systems research: A tutorial overview
  openalex Keith Worden, Wiesław J. Staszewski, James Hensman 2010-11-11 置信度 0.72 Natural computingComputer scienceContext (archaeology)Property (philosophy)Soft computing
• Mapping brain activity at scale with cluster computing
  openalex Jeremy Freeman, Nikita Vladimirov, Takashi Kawashima, Yu Mu 等 2014-07-27 置信度 0.72 Computer scienceConnectomicsBottleneckModular designBig data
• MUMmer4: A fast and versatile genome alignment system
  The MUMmer system and the genome sequence aligner nucmer included within it are among the most widely used alignment packages in genomics. Since the last major release of MUMmer version 3 in 2004, it has been applied to many types of problems including alignin…
  openalex Guillaume Marçais, Arthur L. Delcher, Adam M. Phillippy, Rachel Coston 等 2018-01-26 置信度 0.72 GenomeComputer scienceReference genomeComparative genomicsGenomics
• Unifying niche shift studies: insights from biological invasions
  openalex Antoine Guisan, Blaise Petitpierre, Olivier Broennimann, Curtis C. Daehler 等 2014-03-21 置信度 0.72 NicheEvolutionary biologyBiologyComputational biologyEcology
• A Leaky Integrate-and-Fire Laser Neuron for Ultrafast Cognitive Computing
  We propose an original design for a neuron-inspired photonic computational primitive for a large-scale, ultrafast cognitive computing platform. The laser exhibits excitability and behaves analogously to a leaky integrate-and-fire (LIF) neuron. This model is bo…
  openalex Mitchell A. Nahmias, Bhavin J. Shastri, Alexander N. Tait, Paul R. Prucnal 2013-04-12 置信度 0.72 ScalabilityLaserUltrashort pulseVertical-cavity surface-emitting laserComputer science
• Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
  It is becoming increasingly clear that bistability (or, more generally, multistability) is an important recurring theme in cell signaling. Bistability may be of particular relevance to biological systems that switch between discrete states, generate oscillator…
  openalex David Angeli, James E. Ferrell, Eduardo D. Sontag 2004-02-06 置信度 0.72 MultistabilityBistabilityControl theory (sociology)Positive feedbackBifurcation
• Improving data analysis in herpetology: using Akaike's Information Criterion (AIC) to assess the strength of biological hypotheses
  Abstract In ecology, researchers frequently use observational studies to explain a given pattern, such as the number of individuals in a habitat patch, with a large number of explanatory (i.e., independent) variables. To elucidate such relationships, ecologist…
  openalex Marc J. Mazerolle 2006-01-01 置信度 0.72 Akaike information criterionModel selectionInferenceSelection (genetic algorithm)Set (abstract data type)
• A Biological Computing Algorithm to Solve K-Closure Problem
  openalex Zhaocai Wang, Kai Zhao, Xiaoming Wang, Wei Huang 等 2015-06-18 置信度 0.72 Closure (psychology)Computer scienceAlgorithmEconomicsMarket economy
• Reactome: a knowledge base of biologic pathways and processes
  Reactome http://www.reactome.org, an online curated resource for human pathway data, provides infrastructure for computation across the biologic reaction network. We use Reactome to infer equivalent reactions in multiple nonhuman species, and present data on t…
  openalex Imre Västrik, Peter D’Eustachio, Esther Schmidt, Joshi-Tope Geeta 等 2007-03-16 置信度 0.72 BiologyHuman geneticsComputational biologyGenome BiologyKnowledge base
• Bayesian computing with INLA: New features
  openalex Thiago G. Martins, Daniel Simpson, Finn Lindgren, Håvard Rue 2013-05-02 置信度 0.72 HyperparameterComputer sciencePosterior probabilityBayesian probabilityInference
• In silico prediction of protein-protein interactions in human macrophages
  BACKGROUND: Protein-protein interaction (PPI) network analyses are highly valuable in deciphering and understanding the intricate organisation of cellular functions. Nevertheless, the majority of available protein-protein interaction networks are context-less,…
  openalex Oussema Souiai, Fatma Z. Guerfali, Slimane Ben Miled, Christine Brun 等 2014-01-01 置信度 0.72 InteractomeIn silicoProtein–protein interactionComputational biologyInteraction network
• Continuous development of schemes for parallel computing of the electrostatics in biological systems: Implementation in DelPhi
  Due to the enormous importance of electrostatics in molecular biology, calculating the electrostatic potential and corresponding energies has become a standard computational approach for the study of biomolecules and nano-objects immersed in water and salt pha…
  openalex Chuan Li, Marharyta Petukh, Lin Li, Emil Alexov 2013-06-04 置信度 0.72 Computer scienceElectrostaticsSpeedupMultithreadingComputational science
• Biosensors: fundamentals and applications
  openalex Anthony Turner, Isao Karube, George S. Wilson, Paul J. Worsfold 1987-01-01 置信度 0.72 ChemistryBiosensorNanotechnologyBiochemical engineeringBiochemistry
• Exploration of biological network centralities with CentiBiN
  BACKGROUND: The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Centrality analysis ranks network elements according to their importance within the netw…
  openalex Björn H. Junker, Dirk Koschützki, Falk Schreiber 2006-04-21 置信度 0.72 CentralityBiological networkComputer scienceNetwork analysisNetwork theory
• Parallel distributed computing using Python
  openalex Lisandro Dalcín, Rodrigo R. Paz, Pablo A. Kler, Alejandro Cósimo 2011-04-24 置信度 0.72 Python (programming language)Computer scienceSoftwareExtensibilityParallel computing
• Modeling the role of salience in the allocation of overt visual attention
  openalex Derrick Parkhurst, Klinton Law, Ernst Niebur 2002-01-01 置信度 0.72 Stimulus (psychology)PsychologyEye movementSecond-order stimulusCognitive psychology
• Computing motion using analog and binary resistive networks
  The authors describe recent developments in the theory of early vision that led from the formulation of the motion problem as an ill-posed one to its solution by minimizing certain 'cost' functions. These cost or energy functions can be mapped onto simple anal…
  openalex James Hutchinson, Christof Koch, Jin Luo, Carver Mead 1988-03-01 置信度 0.72 Resistive touchscreenComputer scienceCMOSVery-large-scale integrationNode (physics)
• 2010 Second World Congress on Nature and Biologically Inspired Computing (NaBIC)
  openalex 2010-12-01 置信度 0.72 Computer scienceData science
• Biological interpretation of genome-wide association studies using predicted gene functions
  The main challenge for gaining biological insights from genetic associations is identifying which genes and pathways explain the associations. Here we present DEPICT, an integrative tool that employs predicted gene functions to systematically prioritize the mo…
  openalex Tune H. Pers, Juha Karjalainen, Yingleong Chan, Harm-Jan Westra 等 2015-01-19 置信度 0.72 GeneBiologyComputational biologyGenome-wide association studyGenetics
• Biological response of cancer cells to radiation treatment
  Cancer is a class of diseases characterized by uncontrolled cell growth and has the ability to spread or metastasize throughout the body. In recent years, remarkable progress has been made toward the understanding of proposed hallmarks of cancer development, c…
  openalex Rajamanickam Baskar, Jiawen Dai, Nei Wenlong, R. Yeo 等 2014-11-17 置信度 0.72 Radiation therapyBystander effectCancerRadiosensitivityCancer cell
• An overview of randomization techniques: An unbiased assessment of outcome in clinical research
  Randomization as a method of experimental control has been extensively used in human clinical trials and other biological experiments. It prevents the selection bias and insures against the accidental bias. It produces the comparable groups and eliminates the …
  openalex KP Suresh 2011-01-01 置信度 0.72 RandomizationOutcome (game theory)Selection biasComputer scienceRestricted randomization
• Biologically-Inspired Collaborative Computing
  openalex Mike Hinchey, Hartmut Schmeck, Franz J. Rammig, Anastasia Pagnoni 2008-01-01 置信度 0.72 Computer scienceData scienceScience and engineeringEngineering ethicsEngineering
• Large-scale neuromorphic computing systems
  Neuromorphic computing covers a diverse range of approaches to information processing all of which demonstrate some degree of neurobiological inspiration that differentiates them from mainstream conventional computing systems. The philosophy behind neuromorphi…
  openalex Steve Furber 2016-08-16 置信度 0.72 Neuromorphic engineeringComputer scienceMainstreamScale (ratio)Data science
• Biological Versus Chronological Aging
  Aging is the main risk factor for vascular disease and ensuing cardiovascular and cerebrovascular events, the leading causes of death worldwide. In a progressively aging population, it is essential to develop early-life biomarkers that efficiently identify ind…
  openalex Magda R. Hamczyk, Rosa M. Nevado, Ana Barettino, Valentı́n Fuster 等 2020-02-24 置信度 0.72 MedicineDiseaseBiological agePopulation ageingLife span
• A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge
  openalex Dayoon Kwon, Daniel W. Belsky 2021-11-02 置信度 0.72 Computer scienceBiological ageBiological dataPopulationR package
• Image representation using 2D Gabor wavelets
  This paper extends to two dimensions the frame criterion developed by Daubechies for one-dimensional wavelets, and it computes the frame bounds for the particular case of 2D Gabor wavelets. Completeness criteria for 2D Gabor image representations are important…
  openalex Tai Sing Lee 1996-01-01 置信度 0.72 Gabor waveletWaveletArtificial intelligencePattern recognition (psychology)Gabor filter
• SURF: Speeded Up Robust Features
  openalex Herbert Bay, Tinne Tuytelaars, Luc Van Gool 2006-01-01 置信度 0.72 Computer scienceRobustness (evolution)Artificial intelligenceHessian matrixDetector
• Towards computing with proteins
  Can proteins be used as computational devices to address difficult computational problems? In recent years there has been much interest in biological computing, that is, building a general purpose computer from biological molecules. Most of the current efforts…
  openalex Ron Unger, John Moult 2006-01-24 置信度 0.72 Computer scienceDNA computingComputationRobustness (evolution)NAND gate
• Multiscale Computational Models of Complex Biological Systems
  Integration of data across spatial, temporal, and functional scales is a primary focus of biomedical engineering efforts. The advent of powerful computing platforms, coupled with quantitative data from high-throughput experimental methodologies, has allowed mu…
  openalex Joseph Walpole, Jason A. Papin, Shayn M. Peirce 2013-05-03 置信度 0.72 Computer scienceLeverage (statistics)Data scienceFocus (optics)Multiscale modeling
• Biological variability in maximum aerobic power
  The biological variation in maximum aerobic power (V O2max) was examined in four trained females and one trained male. An average of 8-20 repeat VO2max treadmill tests over a 2-4 wk period were performed on each subject (80 total tests). Biological variation (…
  openalex Victor L. Katch, STANLEY S. SADY, Patty S. Freedson 1982-01-01 置信度 0.72 Standard deviationStatisticsMathematicsVO2 maxTreadmill
• Robust and emergent Physarum logical-computing
  openalex Soichiro Tsuda, Masashi Aono, Yukio‐Pegio Gunji 2003-12-31 置信度 0.72 Physarum polycephalumPhysarumSlime moldComputer scienceUnconventional computing
• Mechanisms of Physical-Biological-Biogeochemical Interaction at the Oceanic Mesoscale
  Mesoscale phenomena are ubiquitous and highly energetic features of ocean circulation. Their influence on biological and biogeochemical processes varies widely, stemming not only from advective transport but also from the generation of variations in the enviro…
  openalex Dennis J. McGillicuddy 2015-09-11 置信度 0.72 Biogeochemical cycleMesoscale meteorologyEphemeral keyEnvironmental scienceBiogeochemistry
• Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1
  BACKGROUND: Micro-computed tomography (micro-CT) is a novel tool for monitoring acute and chronic disease states in small laboratory animals. Its value for assessing progressive lung fibrosis in mice has not been reported so far. Here we examined the importanc…
  openalex Thomas Rodt, Christian von Falck, Sabine Dettmer, Roman Halter 等 2010-12-01 置信度 0.72 Pulmonary fibrosisLungMedicineFibrosisIdiopathic pulmonary fibrosis
• Searching molecular structure databases with tandem mass spectra using CSI:FingerID
  Metabolites provide a direct functional signature of cellular state. Untargeted metabolomics experiments usually rely on tandem MS to identify the thousands of compounds in a biological sample. Today, the vast majority of metabolites remain unknown. We present…
  openalex Kai Dührkop, Huibin Shen, Marvin Meusel, Juho Rousu 等 2015-09-21 置信度 0.72 PubChemFragmentation (computing)Tandem mass spectrometryComputational biologyComputer science
• THE BIOLOGICAL SIGNIFICANCE OF THE THROMBOPLASTIC PROTEIN OF BLOOD
  openalex Erwin Chargaff, Randolph West 1946-11-01 置信度 0.72 ChemistryBiochemistry
• SAGA: a subgraph matching tool for biological graphs
  MOTIVATION: With the rapid increase in the availability of biological graph datasets, there is a growing need for effective and efficient graph querying methods. Due to the noisy and incomplete characteristics of these datasets, exact graph matching methods ha…
  openalex Yuanyuan Tian, Richard C. McEachin, Carlos Santos, David J. States 等 2006-11-16 置信度 0.72 Computer scienceMatching (statistics)GraphBiological networkTheoretical computer science
• Quantum computing and AI in healthcare: Accelerating complex biological simulations, genomic data processing, and drug discovery innovations
  The convergence of quantum computing and artificial intelligence (AI) presents a paradigm shift in healthcare, revolutionizing complex biological simulations, genomic data processing, and drug discovery innovations. Traditional computational methods, despite t…
  openalex Hassan Ali 2023-11-30 置信度 0.72 Drug discoveryData scienceComputer scienceHealth careGenomics
• A Model-Based Approach for Determining Orientations of Biological Macromolecules Imaged by Cryoelectron Microscopy
  openalex Timothy S. Baker, R. Holland Cheng 1996-01-01 置信度 0.72 MicroscopyIcosahedral symmetryBiological systemOrientation (vector space)Symmetry (geometry)
• BioAmbients: an abstraction for biological compartments
  openalex Aviv Regev, Ekaterina M. Panina, William B. Silverman, Luca Cardelli 等 2004-04-26 置信度 0.72 Compartmentalization (fire protection)Process calculusAbstractionComputer scienceModular design
• Biologically inspired intelligent robots
  Humans throughout history have always sought to mimic the appearance, mobility, functionality, intelligent operation, and thinking process of biological creatures. This field of biologically inspired technology, having the moniker biomimetics, has evolved from…
  openalex Yoseph Bar‐Cohen, Cynthia Breazeal 2003-07-28 置信度 0.72 RobotBiomimeticsComputer scienceNoticeCreatures
• New Computational Paradigms: Changing Conceptions of What is Computable
  openalex S. Barry Cooper, Benedikt Lwe, Andrea Sorbi 2007-12-12 置信度 0.72 ComputabilityComputability theoryDecidabilityComputable analysisComputable function
• RCSB Protein Data Bank: biological macromolecular structures enabling research and education in fundamental biology, biomedicine, biotechnology and energy
  The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center for the global PDB archive, serves thousands of Data Depositors in the Americas and Oceania and makes 3D macromolecular structure data available…
  openalex S.K. Burley, Helen M. Berman, Charmi Bhikadiya, Chunxiao Bi 等 2018-10-11 置信度 0.72 BiologyBiomedicineProtein Data BankComputational biologyBiotechnology
• Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
  The cBioPortal for Cancer Genomics (http://cbioportal.org) provides a Web resource for exploring, visualizing, and analyzing multidimensional cancer genomics data. The portal reduces molecular profiling data from cancer tissues and cell lines into readily unde…
  openalex Jianjiong Gao, Bülent Arman Aksoy, Uğur Doğrusöz, Gideon Dresdner 等 2013-04-02 置信度 0.72 GenomicsVisualizationInterface (matter)Computer scienceComputational biology
• Content Extraction of Biological Datasets Using Soft Computing Techniques
  openalex Kolla Bhanu Prakash, Madhavi Rangaswamy 2016-08-01 置信度 0.72 Computer scienceExtraction (chemistry)Soft computingArtificial intelligencePattern recognition (psychology)
• Biologically-Inspired Computing Approaches To Cognitive Systems: a partial tour of the literature
  cognitive systems, biologicallyinspired computing, artificial life, artificial intelligence, autonomous agents This paper presents a review of the academic literature on biologicallyinspired computing approaches to the science and engineering of cognitive syst…
  openalex Dave Cliff 2003-01-01 置信度 0.72 Reading (process)CognitionComputer scienceCognitive scienceCognitive computing
• Superconducting Optoelectronic Circuits for Neuromorphic Computing
  To realize functionality similar to that of their biological inspirations, advanced neuromorphic systems require massive interconnectivity, extreme energy efficiency, and complex signaling mechanisms. The authors propose an integrated optoelectronic platform c…
  openalex Jeffrey M. Shainline, Sonia Buckley, Richard P. Mirin, Sae Woo Nam 2017-03-23 置信度 0.72 Neuromorphic engineeringInterconnectivityElectronicsPhotonicsComputer science
• Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints
  openalex Scott J. Hollister, Rosanna Maddox, Juan M. Taboas 2002-10-01 置信度 0.72 ScaffoldMaterials scienceBiomedical engineeringTissue engineeringFabrication
• The BioPAX community standard for pathway data sharing
  openalex Emek Demir, Michael P. Cary, Suzanne Paley, Ken Fukuda 等 2010-09-01 置信度 0.72 Computer scienceBiological pathwayBiological dataData exchangeVisualization
• Uncovering biological network function via graphlet degree signatures.
  MOTIVATION: Proteins are essential macromolecules of life and thus understanding their function is of great importance. The number of functionally unclassified proteins is large even for simple and well studied organisms such as baker's yeast. Methods for dete…
  openalex Tijana Milenković, Nataša Pržulj 2008-01-01 置信度 0.72 Protein function predictionProteomeComputational biologyBiological networkFunction (biology)