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Mechanical stress on joint tissues is a central driver of osteoarthritis (OA), yet our understanding of OA pathomechanics remains incomplete, obstructing etiology-driven personalized treatments. Current joint assessment approaches are largely monodisciplinary.…
pubmed
Schallig W, Dur NBJ, Wesseling MGH, van der Heijden RA 等
2026 Jul 11
置信度 0.82
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Advances in asthma immunopathology and the integration of biologic therapies have reshaped clinical practice, and in turn have impacted diagnosis, phenotyping, monitoring, and care organization. Given the persistent burden of chronic obstructive pulmonary dise…
pubmed
de Miguel-Díez J, Callejas-González FJ, Blanco-Aparicio M, Cosío BG 等
2026 Aug 24
置信度 0.82
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Naturally occurring in animals, plants, and other organisms, peptides exhibit strong antibacterial activity and hold promise as alternatives to conventional antibiotics. However, evaluating peptide properties such as toxicity, antibacterial activity, and antic…
pubmed
Wu H, Deng Y, Li Z, Qi M 等
2026 Aug 24
置信度 0.82
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Single-cell RNA sequencing (scRNA-seq) provides transcriptomic profiles at cellular resolution, enabling the study of tissue heterogeneity. A critical step in scRNA-seq analysis is cell clustering, which identifies distinct subpopulations for downstream biolog…
pubmed
Su W, Qin B, Shang J, Zhao Y 等
2026 Aug 24
置信度 0.82
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Non-nutritive sweeteners (NNS) are commonly used in the beverage, food, and pharmaceutical industries, however, their possible link to neuroinflammation remains a contentious issue. Hence, to investigate this potential association and identify the mo…
pubmed
Chakraborty S, Manickam V
2026 Aug 24
置信度 0.82
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Prediabetes is a well-established risk factor for late-life dementia, and phenotypic age acceleration (PhenoAgeAccel) serves as a reliable biomarker reflecting cumulative biological aging burden. Few population-based cohorts have clarified their combined corre…
pubmed
Zhang Z, Zhou H, Liu BX, Dai XJ
2026 Aug 24
置信度 0.82
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Sorting, filtering, and controlling colloidal particles is crucial in many fields, ranging from chemistry to biology and physics. Dielectrophoresis (DEP) enables selective manipulation of colloids by non-uniform AC electric fields, yet the associated three-dim…
pubmed
de Jong F, Diez-Silva P, Chen JK, Peláez RP 等
2026 Aug 24
置信度 0.82
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Unicoronal craniosynostosis (UCS) involves premature fusion of the left or right coronal suture, resulting in skull deformities and facial asymmetry. Fronto-orbital distraction (FOD) has proven effective for surgically correcting UCS; however, determining opti…
pubmed
Samiepour Y, Mellgren J, Liang C, Cox PG 等
2026 Aug 24
置信度 0.82
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P300-based brain-computer interface augmentative and alternative communication (P300-BCI-AAC) systems show promise for supporting communication for children with severe speech and physical impairments. However, little is known about how children prefer these d…
pubmed
Pitt KM, Thiessen A, Fowler G, Butler E
2026 Aug 24
置信度 0.82
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Non-invasive preimplantation genetic testing (niPGT) using cell-free DNA (cfDNA) extracted from spent embryo culture medium (SECM) has shown great potential, providing economic and practical advantages for embryo ploidy testing and quality assessment, while mi…
pubmed
Zhou X, Ding S, Zhang Z, Shangguan Q 等
2026 Aug 24
置信度 0.82
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Animals rely on diverse molecular mechanisms to maintain beneficial microbial associations while also defending against pathogens, yet the extent to which these responses vary among genotypes of a single species remains poorly understood. Using individuals fro…
pubmed
Clark J, Krueger Q, Carrier TJ, Moran Y 等
2026 Aug
置信度 0.82
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We establish a definition of ordinal patterns for multivariate data sets based on the concept of Tukey's halfspace depth. Given the definition of these depth patterns, we are interested in the probabilities of observing specific patterns in time series. For th…
pubmed
Betken A, Schnurr A
2026 Aug 1
置信度 0.82
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In this paper, the complex epidemic behavior of higher-order interactions is investigated by considering heterogeneous hypernetworks with collective contagion mechanisms, and a susceptible-infected-recovered-susceptible epidemic model is established in hyperne…
pubmed
Wang W, Zhang J, Jin Z
2026 Aug 1
置信度 0.82
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We compute the longitudinal dielectric function ɛl(k) for p-point water models, p = 3 (SPC/E, TIP3P), p = 4 (TIP4P-EW, OPC), and p = 5 (TIP5P-E) from the charge-charge fluctuation function SZZ(k), obtained from two methods: average of the charge in k-spa…
pubmed
Shevy N, Kakkar P, Travesset A
2026 Aug 28
置信度 0.82
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Generative models for protein backbone design have to simultaneously ensure geometric validity, sampling efficiency, and scalability to long protein chains. However, most existing approaches rely on iterative refinement, quadratic attention mechanisms, or post…
pubmed
Wu T, Zhu L
2026 Aug 1
置信度 0.82
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Three-dimensional folding of the genome into structures such as chromatin loops is essential for gene regulation. Current experimental methods for mapping these structures, like Hi-C and HiChIP, are labor-intensive and require repeated assays to test hypothesi…
pubmed
Hönig S, Grover A, Neri P, Surdez D 等
2026 Aug 1
置信度 0.82
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Peptide-MHC II binding drives adaptive immunity, yet discovery of novel binder peptides remains challenging due to open binding grooves of MHC-II that accommodate variable-length peptides. While discriminative models perform well, they are unfeasible for gener…
pubmed
Korpela D, Dumitrescu A, Stražar M, Li R 等
2026 Aug 1
置信度 0.82
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Perineural invasion (PNI) is an important pathological phenotype associated with poor prognosis in multiple malignancies. The primary detection method is visual inspection of whole slide images (WSIs), which is labor-intensive, time-consuming, subjective, and …
pubmed
Alkhan A, Lynch M, Ryan EJ, Lavelle M 等
2026 Aug 1
置信度 0.82
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Molecular representation learning is central to computational drug discovery. However, most existing models rely on single-modality inputs, such as molecular sequences or graphs, which capture only limited aspects of molecular behaviour. Yet unifying these mod…
pubmed
Ulusoy E, Bostancı Ş, Deniz BE, Doğan T
2026 Aug 1
置信度 0.82
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Long non-coding RNAs (lncRNAs) regulate gene expression, chromatin organization, and cellular signaling. Recent studies indicate that ∼20% of the ∼36 000 human lncRNA genes harbor small open reading frames (sORFs) capable of producing micr…
pubmed
Zok S, Linial M
2026 Aug 1
置信度 0.82
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Bulk RNA-seq deconvolution methods rely on single-cell reference data to estimate cell-type proportions in heterogeneous tissues, but certain cell types may be systematically absent from single-cell references due to technical limitations such as poor dissocia…
pubmed
Fan Y, Liu Y, Zhong Y, Wang Y 等
2026 Aug 1
置信度 0.82
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Recent advances in inference of the ancestral recombination graph (ARG), which describes how segments of chromosomes trace back through recombination and shared lineages, have made it possible to reconstruct genome-wide genealogies for large cohorts, but it re…
pubmed
Bonet D, Shanks C, Cara MC, Abante J 等
2026 Aug 1
置信度 0.82
-
Protein kinases are key regulators of cellular signaling and are frequently implicated in human diseases. Although kinase domains are structurally conserved, predicting the effects of amino acid substitutions remains challenging as mutations often introduce su…
pubmed
Fadaei S, Krebs FS, Zoete V
2026 Aug 1
置信度 0.82
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In Baker's yeast, there exists a comprehensive collection of pairwise epistasis experiments that, for nearly every pair of non-essential genes, measures the growth of the double-knockout strain as compared to its component single knockouts. This data can be re…
pubmed
Garcia JJ, Yu KM, Freudenreich CH, Cowen LJ
2026 Aug 1
置信度 0.82
-
Bacterial phase variation enables reversible, locus-specific phenotypic switching, often driven by DNA inversion (invertons). To identify these events, researchers commonly rely on sequencing reads that provide orientation-specific support. Metagenomic sequenc…
pubmed
Lu Y, Guan J, Shen Y, Shang J 等
2026 Aug 1
置信度 0.82
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Cell differentiation is a dynamic process in which cells traverse through high-dimensional gene expression space under the influence of gene regulatory networks and environmental cues. Recent advances in single-cell RNA sequencing (scRNA-seq) have enabled us t…
pubmed
Noman AA, Sashittal P
2026 Aug 1
置信度 0.82
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Record-seq captures cumulative transcriptional activity over time in engineered Escherichia coli by integrating cellular RNA-derived spacer sequences into clustered regularly interspaced short palindromic repeats (CRISPR) arrays, which are read out by sequenci…
pubmed
Hugi F, Tanna T, Platt RJ
2026 Aug 1
置信度 0.82
-
Protein Language Models (PLMs) have revolutionized protein engineering by capturing the evolutionary constraints inherent in natural protein sequences. However, precisely steering these models to engineer novel proteins with targeted functionalities remains ch…
pubmed
Qayyum ABA, Zhou Y, Qian X, Yoon BJ
2026 Aug 1
置信度 0.82
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Spatial computational models such as agent-based models (ABMs) offer powerful in silico tools to study tumor dynamics, yet imaging data are still rarely used to inform these models directly.
pubmed
Wang BR, Liao CY, Danen EHJ, Neubert E 等
2026 Aug 1
置信度 0.82
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Accurate prediction of drug-target interactions (DTIs) is fundamental to drug discovery and mechanistic understanding. While deep learning has advanced computational DTI prediction, most existing methods rely primarily on molecular structural representations, …
pubmed
Lai YJ, Liang T, Chen PY, Tsai YC 等
2026 Aug 1
置信度 0.82
-
Proteolysis-targeting chimeras (PROTACs) enable targeted protein degradation by recruiting an E3 ubiquitin ligase to a protein of interest (POI) and forming a ternary complex. Despite their therapeutic promise, rational PROTAC design remains challenging, as de…
pubmed
Chen K, Huang Z, Wang Y, Shen S 等
2026 Aug 1
置信度 0.82
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Nonribosomal peptides (NRPs) are bioactive microbial metabolites with high pharmaceutical potential. Although genome mining enables large-scale detection of biosynthetic gene clusters (BGCs) predicted to encode NRPs, reliably linking these clusters to their ch…
pubmed
Olkhovskii I, Kushnareva A, Tagirdzhanov A, Gurevich A
2026 Aug 1
置信度 0.82
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Spatial transcriptomics (ST) technologies profile gene expression while preserving tissue architecture, enabling the study of spatial cellular organization and microenvironmental interactions. However, raw ST data are heavily affected by technical noise, spars…
pubmed
Ansari MI, Alif MN, Zhang W
2026 Aug 1
置信度 0.82
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Universal differential equations (UDEs) have emerged as a powerful tool for scientific discovery, uniting differential equations and deep learning. Yet, their application to the noisy and complex data of systems biology remains limited. Here, we demonstrate th…
pubmed
Kaya UC, Kodragjini X, Zambrano S, Baum K
2026 Aug 1
置信度 0.82
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A central goal in human gut microbiome research is to identify disease-associated functional shifts, an objective increasingly pursued through metagenomic and metabolomic assays. However, common differential abundance analyses of genes or metabolites often yie…
pubmed
Muller E, Baum S, Borenstein E
2026 Aug 1
置信度 0.82
-
RNA-binding proteins (RBPs) regulate post-transcriptional processes, yet many remain undiscovered because RNA-binding activity often occurs outside canonical RNA-binding domains (RBDs), including within intrinsically disordered regions (IDRs) or through protei…
pubmed
Firmani S, Steinbauer F, Kasneci G, Marsico A 等
2026 Aug 1
置信度 0.82
-
Knowledge-guided learning offers effective and robust model training strategies in data-scarce settings by incorporating established domain knowledge, thereby enhancing generalization, robustness, and interpretability. By contrast, conventional deep learning a…
pubmed
Baek B, Jang E, Parsa SP, Kim Y 等
2026 Aug 1
置信度 0.82
-
Identifying drug targets is fundamental in drug development, both for discovering new therapies and for ensuring effective and safe treatments. Drug-target interactions (DTIs) have been predicted using machine learning approaches that integrate heterogeneous d…
pubmed
Noto S, Ferreyra S, Jimenez R, Galeano D 等
2026 Aug 1
置信度 0.82
-
This paper explores the design and implementation of dynamically reconfigurable hardware architectures leveraging the principles of cellular automata (CA). The core concept involves creating a hardware system composed of interconnected computational cells oper…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper explores the design and implementation of dynamically reconfigurable hardware architectures leveraging the principles of cellular automata (CA). The core concept involves creating a hardware system composed of interconnected computational cells oper…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel hardware accelerator architecture inspired by the structure and function of biological neural networks. The core idea is to leverage the inherent parallelism and energy efficiency of Spiking Neural Networks (SNNs) for accelerated co…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel hardware accelerator architecture inspired by the structure and function of biological neural networks. The core idea is to leverage the inherent parallelism and energy efficiency of Spiking Neural Networks (SNNs) for accelerated co…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
Official Publication & Source Code Release This repository contains the full academic manuscript, simulation source code, and data visualizations for our research into the statistical mechanics and thermodynamic properties of Organoid Intelligence (OI) and bio…
datacite
Anikesh0415
2026
置信度 0.66
-
Official Publication & Source Code Release This repository contains the full academic manuscript, simulation source code, and data visualizations for our research into the statistical mechanics and thermodynamic properties of Organoid Intelligence (OI) and bio…
datacite
Anikesh0415
2026
置信度 0.66
-
This paper explores the potential of leveraging biological neural networks' distributed learning mechanisms for novel approaches in distributed computing. The core argument posits that the inherent resilience and efficiency observed in biological systems can i…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper explores the potential of leveraging biological neural networks' distributed learning mechanisms for novel approaches in distributed computing. The core argument posits that the inherent resilience and efficiency observed in biological systems can i…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
CL1-MOT-ZENZ: A Theorem-Safe Certification Layer for Observable Adaptive Geometry in Closed-Loop Biological Neural Networks Authors:Vitaliy Bazarov (ORCID: 0009-0007-9967-5807) Abstract:We present a formal analytical and control layer for Cortical Labs CL1-sty…
datacite
Bazarov (VIT-BAZ), Vitaly
2026
置信度 0.66
-
CL1-MOT-ZENZ: A Theorem-Safe Certification Layer for Observable Adaptive Geometry in Closed-Loop Biological Neural Networks Authors:Vitaliy Bazarov (ORCID: 0009-0007-9967-5807) Abstract:We present a formal analytical and control layer for Cortical Labs CL1-sty…
datacite
Bazarov (VIT-BAZ), Vitaly
2026
置信度 0.66
-
This paper proposes a novel learning algorithm, Neuromorphic Computing-Based Bio-Inspired Learning Algorithm (NCBBLA), designed to enhance the learning efficiency and performance of neuromorphic computing systems. The core claim is that the learning mechanisms…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel learning algorithm, Neuromorphic Computing-Based Bio-Inspired Learning Algorithm (NCBBLA), designed to enhance the learning efficiency and performance of neuromorphic computing systems. The core claim is that the learning mechanisms…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel approach to computing utilizing adaptive networks rooted in neuromorphic principles. The core claim is to design a system capable of achieving low-power, high-efficiency parallel computation by mimicking biological neural networks. …
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel approach to computing utilizing adaptive networks rooted in neuromorphic principles. The core claim is to design a system capable of achieving low-power, high-efficiency parallel computation by mimicking biological neural networks. …
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel computing architecture inspired by the structure and function of biological neurons. The core claim is that mimicking the information processing and storage mechanisms found in neurons can lead to a computing architecture with inher…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper proposes a novel computing architecture inspired by the structure and function of biological neurons. The core claim is that mimicking the information processing and storage mechanisms found in neurons can lead to a computing architecture with inher…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper explores the potential of dynamic topology neural morphic computing, a novel approach to computation inspired by the adaptive and evolving nature of biological neural networks. The core claim is that by simulating the self-adaptive connections and d…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper explores the potential of dynamic topology neural morphic computing, a novel approach to computation inspired by the adaptive and evolving nature of biological neural networks. The core claim is that by simulating the self-adaptive connections and d…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
Neuromorphic computing, inspired by the human brain, seeks to mimic its architecture and processing paradigms for efficient and energy-conscious computation. Traditional digital neural network simulators, while valuable, often struggle to accurately represent …
datacite
Zhang, Jincheng
2026
置信度 0.66
-
Neuromorphic computing, inspired by the human brain, seeks to mimic its architecture and processing paradigms for efficient and energy-conscious computation. Traditional digital neural network simulators, while valuable, often struggle to accurately represent …
datacite
Zhang, Jincheng
2026
置信度 0.66
-
Occurrence-level computational assignments for acquired antimicrobial resistance determinants across complete closed bacterial genomes, with genome-wide structural insertion-sequence annotation added in version 2. 74,349 acquired antimicrobial resistance gene …
datacite
Piranfar, vahhab
2026
置信度 0.66
Plasmidsantimicrobial resistanceChromosomesmobile genetic elementhost-conditioned portability
-
Occurrence-level computational assignments for acquired antimicrobial resistance determinants across complete closed bacterial genomes, with genome-wide structural insertion-sequence annotation added in version 2. 74,349 acquired antimicrobial resistance gene …
datacite
Piranfar, vahhab
2026
置信度 0.66
Plasmidsantimicrobial resistanceChromosomesmobile genetic elementhost-conditioned portability
-
This paper explores the potential of utilizing multi-mode optical fields to create self-organizing photonic neural networks, mimicking and ultimately enabling computational functionalities observed in biological neuronal networks. The core principle relies on …
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This paper explores the potential of utilizing multi-mode optical fields to create self-organizing photonic neural networks, mimicking and ultimately enabling computational functionalities observed in biological neuronal networks. The core principle relies on …
datacite
Zhang, Jincheng
2026
置信度 0.66
-
تحلیل فوقدکتری جامع، فوقتخصصی، بدون کوچکترین سادهسازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۷۱ از ۱۰۰ (فاز پیشرفته مهندسی ارگانیک و بیوفیزیک فرین در پروتکل جامع فیزیک اطلاعات حمزه) با نام تجاری HamzahXcell: «ماتریس توپولوژیک میدانهای چرخش فرومونیک-کوا…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
تحلیل فوقدکتری جامع، فوقتخصصی، بدون کوچکترین سادهسازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۷۱ از ۱۰۰ (فاز پیشرفته مهندسی ارگانیک و بیوفیزیک فرین در پروتکل جامع فیزیک اطلاعات حمزه) با نام تجاری HamzahXcell: «ماتریس توپولوژیک میدانهای چرخش فرومونیک-کوا…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
This research investigates the potential of utilizing quantum entanglement to simulate information encoding and decoding mechanisms within biological neural networks. The core premise is that quantum phenomena, specifically entanglement, may play a more signif…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
This research investigates the potential of utilizing quantum entanglement to simulate information encoding and decoding mechanisms within biological neural networks. The core premise is that quantum phenomena, specifically entanglement, may play a more signif…
datacite
Zhang, Jincheng
2026
置信度 0.66
-
تحلیل فوقدکتری جامع، فوقتخصصی، بدون کوچکترین سادهسازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۶۱ از ۱۰۰ (فاز پیشرفته کلاننظریهها و مهندسی پروتکلهای خلاء با نام تجاری HamzahXcell): «کدگذاری فرکانسهای میدان شبهذرهای اکسیوتون برای هک پروتکلهای بازتاب…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
تحلیل فوقدکتری جامع، فوقتخصصی، بدون کوچکترین سادهسازی و کاملاً ضدگلوله برای نظریه و معمای شماره ۶۱ از ۱۰۰ (فاز پیشرفته کلاننظریهها و مهندسی پروتکلهای خلاء با نام تجاری HamzahXcell): «کدگذاری فرکانسهای میدان شبهذرهای اکسیوتون برای هک پروتکلهای بازتاب…
datacite
HAMZAH, SEYED RASOUL
2026
置信度 0.66
-
BACKGROUND: Widespread adoption of high-throughput sequencing has greatly increased the scale and sophistication of computational infrastructure needed to perform genomic research. An alternative to building and maintaining local infrastructure is "cloud compu…
openalex
Enis Afgan, Dannon Baker, Nate Coraor, Brad Chapman 等
2010-12-01
置信度 0.72
Cloud computingComputer scienceSuiteSoftwareComputer cluster
-
openalex
Xingyuan Xu, Mengxi Tan, Bill Corcoran, Jiayang Wu 等
2021-01-06
置信度 0.72
Computer scienceConvolutional neural networkTOPSArtificial intelligenceDeep learning
-
The graphics processing unit (GPU) has emerged as a computational accelerator that dramatically reduces the time to discovery in high-end computing (HEC). However, while today's state-of-the-art GPU can easily reduce the execution time of a parallel code by ma…
openalex
Shi‐Yu Huang, Shiyu Xiao, Wu-chun Feng
2009-05-01
置信度 0.72
Computer scienceGraphics processing unitCentral processing unitGraphicsEnergy consumption
-
The Advanced Normalizations Tools ecosystem, known as ANTsX, consists of multiple open-source software libraries which house top-performing algorithms used worldwide by scientific and research communities for processing and analyzing biological and medical ima…
openalex
Nicholas J. Tustison, Philip A. Cook, Andrew J. Holbrook, Hans J. Johnson 等
2021-04-27
置信度 0.72
Computer sciencePython (programming language)WorkflowSoftwareNormalization (sociology)
-
openalex
Gudrun Feuchtner, Paul Stolzmann, Wolfgang Dichtl, Thomas Schertler 等
2009-01-28
置信度 0.72
MedicineInfective endocarditisRadiologyAbscessEndocarditis
-
openalex
Simone Scardapane, J.B. Butcher, Filippo Maria Bianchi, Zeeshan Khawar Malik
2017-04-27
置信度 0.72
Computer scienceReservoir computingArtificial intelligenceCognitive scienceData science
-
This paper describes a free energy principle that tries to explain the ability of biological systems to resist a natural tendency to disorder. It appeals to circular causality of the sort found in synergetic formulations of self-organization (e.g., the slaving…
openalex
Karl Friston
2012-10-31
置信度 0.72
Principle of least actionStatistical physicsGeneralityVariational principleInformation bottleneck method
-
Unscheduled increment of load variation in a power transmission system has driven the system to experience stressed condition leading to potential cascading trip on the entire system. Thus, close monitoring of load variation in a power network can help in avoi…
openalex
Nur Dianah Mohd. Radzi, Ismail Musirin, Mohamad Khayat Idris, Abdul Rahman Minhat 等
2007-12-14
置信度 0.72
Electric power systemUnified power flow controllerAC powerCapacitorVoltage
-
openalex
Wei Qi Yan, Minh Nguyen, Martin Stommel
2023-01-01
置信度 0.72
Computer scienceGenerative grammarAdversarial systemConvolutional neural networkArtificial intelligence
-
openalex
Christopher R. Lowe
2000-08-01
置信度 0.72
NanomanufacturingNanotechnologyNanobiotechnologyFabricationBiocomposite
-
We present GOseq, an application for performing Gene Ontology (GO) analysis on RNA-seq data. GO analysis is widely used to reduce complexity and highlight biological processes in genome-wide expression studies, but standard methods give biased results on RNA-s…
openalex
Matthew D. Young, Matthew J. Wakefield, Gordon K. Smyth, Alicia Oshlack
2010-02-04
置信度 0.72
BiologyRNA-SeqGene ontologyHuman geneticsComputational biology
-
Fine structural details of glycans attached to the conserved N-glycosylation site significantly not only affect function of individual immunoglobulin G (IgG) molecules but also mediate inflammation at the systemic level. By analyzing IgG glycosylation in 5,117…
openalex
Jasminka Krištić, Frano Vučković, Cristina Menni, Lucija Klarić 等
2013-12-10
置信度 0.72
GlycosylationGlycanBiological ageInflammationN-linked glycosylation
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The National Center for Biomedical Ontology (NCBO) is one of the National Centers for Biomedical Computing funded under the NIH Roadmap Initiative. Contributing to the national computing infrastructure, NCBO has developed BioPortal, a web portal that provides …
openalex
Patricia L. Whetzel, Natasha Noy, Nigam H. Shah, Paul R. Alexander 等
2011-06-14
置信度 0.72
Open Biomedical OntologiesOntologyWorld Wide WebComputer scienceOWL-S
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Computers have advanced beyond the desktop into many parts of everyday life.Ubiquitous Computing is inevitably computing in context: it takes place in situations in the real world.So far most research, especially in mobile computing, has focused on enabling tr…
openalex
Albrecht Schmidt
2003-01-01
置信度 0.72
Ubiquitous computingEnd-user computingComputer scienceContext (archaeology)Context-aware pervasive systems
-
Using aqueous cyanobacterial extracts in the synthesis of silver nanoparticle is looked as green, ecofriendly, low priced biotechnology that gives advancement over both chemical and physical methods. In the current study, an aqueous extract of Oscillatoria lim…
openalex
Ragaa A. Hamouda, Mervat H. Hussein, Rasha A. Abo-Elmagd, Salwa S. Bawazir
2019-09-10
置信度 0.72
Nuclear chemistryOscillatoriaSilver nanoparticleAqueous solutionAntibacterial activity
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Petri nets are a general and well-established model of concurrent and distributed computation and behaviour, including that taking place in biological systems. In this survey paper, we are concerned with intrinsic relationships between Petri nets and two forma…
openalex
Jetty Kleijn, Maciej Koutny, Grzegorz Rozenberg
2011-01-01
置信度 0.72
Petri netComputer scienceProgramming language
-
openalex
M. Prezioso, Farshad Merrikh‐Bayat, Brian D. Hoskins, Gina C. Adam 等
2015-05-01
置信度 0.72
MemristorNeuromorphic engineeringCrossbar switchComputer scienceTransistor
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Biodiversity data -covering all types of data utilized in ecology, genetics and taxonomy.Biological sample -any DNA, tissue, specimen, soil, water, air, etc. sample which includes biological material.Cloud database -database hosting data that consists of virtu…
openalex
Kessy Abarenkov
2011-10-04
置信度 0.72
Cloud computingComputer scienceDatabaseData scienceWorld Wide Web
-
openalex
Maddalena Venturoli, M MADDALENASPEROTTO, M KRANENBURG, Berend Smit
2006-11-20
置信度 0.72
Mesoscopic physicsMembranePhysicsLipid bilayerBilayer
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MOTIVATION: Prior biological knowledge greatly facilitates the meaningful interpretation of gene-expression data. Causal networks constructed from individual relationships curated from the literature are particularly suited for this task, since they create mec…
openalex
A. Krämer, Jeff Green, Jack Pollard, Stuart Tugendreich
2013-12-13
置信度 0.72
IngenuityDownstream (manufacturing)Upstream (networking)Computer scienceNetwork analysis
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MOTIVATION: Many practical pattern recognition problems require non-negativity constraints. For example, pixels in digital images and chemical concentrations in bioinformatics are non-negative. Sparse non-negative matrix factorizations (NMFs) are useful when t…
openalex
Hyunsoo Kim, Haesun Park
2007-05-05
置信度 0.72
Non-negative matrix factorizationComputer sciencePattern recognition (psychology)Sparse matrixCluster analysis
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CONTEXT: The standard criteria used to evaluate tumor response, the Response Evaluation Criteria in Solid Tumors (RECIST), were developed to assess tumor shrinkage after cytotoxic chemotherapy and may be limited in assessing response to biologic agents, which …
openalex
Yun Shin Chun
2009-12-01
置信度 0.72
MedicineBevacizumabResponse Evaluation Criteria in Solid TumorsColorectal cancerInterquartile range
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openalex
Caroline A Schneider, Wayne Rasband, Kevin W. Eliceiri
2012-06-28
置信度 0.72
SoftwareImage (mathematics)Computer scienceData scienceImage processing
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MOTIVATION: Experiments such as ChIP-chip, ChIP-seq, ChIP-PET and DamID (the four methods referred herein as ChIP-X) are used to profile the binding of transcription factors to DNA at a genome-wide scale. Such experiments provide hundreds to thousands of poten…
openalex
Alexander Lachmann, Huilei Xu, Jayanth Krishnan, Seth Berger 等
2010-08-13
置信度 0.72
Transcription factorGeneDatabaseComputational biologyTranscription (linguistics)
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Magnonics addresses the physical properties of spin waves and utilizes them for data processing. Scalability down to atomic dimensions, operation in the GHz-to-THz frequency range, utilization of nonlinear and nonreciprocal phenomena, and compatibility with CM…
openalex
Andrii V. Chumak, Pavel Kaboš, Mingzhong Wu, Claas Abert 等
2022-02-07
置信度 0.72
MagnonicsNeuromorphic engineeringComputer scienceScalabilityPhysics
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openalex
David Cox, Thomas Dean
2014-09-01
置信度 0.72
BiologyNeuroscienceCognitive scienceSystems neuroscienceArtificial intelligence
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BACKGROUND: Valve calcification is well estimated by ex-vivo micro-computed tomography (micro-CT). The objective of this study was to investigate the associations between micro-CT findings and biological indices of calcification in aortic stenosis (AS), as wel…
openalex
Piotr Mazur, Ewa Wypasek, Bogusław Gawęda, Dorota Sobczyk 等
2017-01-01
置信度 0.72
CalcificationBicuspid aortic valveMedicineStenosisComputed tomography
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Social Computing and online communities have ushered in a new era of the web, where information and communication technologies are facilitating organized human endeavor in fundamentally new ways. The broad impact of social computing in diverse domains and the …
openalex
Manoj Parameswaran, Andrew B. Whinston
2007-06-01
置信度 0.72
Social computingComputer scienceData scienceKnowledge managementField (mathematics)
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Ordinateurs du futur, bases sur la combinaison de la genomique et des nanotechnologies, utilisant des organismes vivants
openalex
Nancy K. Herther
2003-01-01
置信度 0.72
GenomicsData scienceComputer scienceNanotechnologyWorld Wide Web
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ABSTRACT Aim Spatial modelling techniques are increasingly used in species distribution modelling. However, the implemented techniques differ in their modelling performance, and some consensus methods are needed to reduce the uncertainty of predictions. In thi…
openalex
Mathieu Marmion, Miia Parviainen, Miska Luoto, Risto K. Heikkinen 等
2008-12-08
置信度 0.72
Random forestReceiver operating characteristicThreatened speciesStatisticsEnvironmental niche modelling
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Several strategies have been proposed to provide quality solutions to the unit commitment problem and increase the potential saving in the power system operation. These include deterministic and stochastic search algorithms. One of the limitations of determini…
openalex
Lingamurthy Belede, Amit Jain, Ravikanth Reddy Gaddam
2009-01-01
置信度 0.72
Power system simulationCurse of dimensionalityComputer scienceField (mathematics)Quality (philosophy)
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The proliferation of Internet technologies, services and devices, have made the current networked system designs, and management tools incapable of designing reliable, secure networked systems and services. In fact, we have reached a level of complexity, heter…
openalex
Xiangdong Dong, Salim Hariri, Lizhi Xue, Huoping Chen 等
2003-10-31
置信度 0.72
Autonomic computingComputer scienceMiddleware (distributed applications)Software deploymentQuality of service