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This paper introduces an open-source active high-precision signal amplifier designed for enhancing biodata acquisition, specifically focusing on EEG signals. The compact device, with a diameter of 18 mm, seamlessly integrates electronics, signal processing, an…
preprints
2024
置信度 0.74
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A serious game combines concepts, principles, and methods of game design with information and communication technologies, for the achievement of a given goal beyond entertainment. Serious game studies have been reported under a brain-computer interface (BCI) a…
preprints
2024
置信度 0.74
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ABSTRACT Neuroscientists employ various experimental procedures to interface with the brain to study and perturb the neural activity during behavior. A common procedure that allows such physical interfacing is cranial microsurgery, wherein small to large crani…
preprints
2024
置信度 0.74
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Dyslexia is a learning disorder impacting reading, writing, calculation, memory, and spelling abilities. It is a neurodevelopmental condition affecting approximately 5-10% of the population. The use of eye tracking combined with machine learning algorithms for…
preprints
2024
置信度 0.74
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The article presents an accessible route into the field of neuroscience through ardEEG device. This device allows convert Arduino UNO R4 WIFI into a brain-computer interface, making it easy to measure EEG, EMG and ECG signals with 8 channels. Over the past dec…
preprints
2024
置信度 0.74
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A bstract As brain-computer interface (BCI) research advances, many new applications are being developed. Tasks can be performed in different environments, and whether a BCI user can switch environments seamlessly will influence the ultimate utility of a clini…
preprints
2024
置信度 0.74
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In the application of motor imagery brain-computer interface system, high-density leads bring redundant noise, which leads to time-consuming system operation and poor performance. A channel selection strategy based on brain function network is proposed. This m…
preprints
2024
置信度 0.74
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Abstract Background A brain-computer interface (BCI) is a system that makes communication between the brain and an external device. The electroencephalogram (EEG) is the most favourable tool for extracting neural signals from the brain. Motor Imagery (MI) base…
preprints
2024
置信度 0.74
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Social robots hold promise for enhancing later-life support, but user needs and preferences for multimodal interaction modalities remain underexplored. This study explores awareness, willingness, perceived barriers, and modality-function associations across mu…
europepmc
2026
置信度 0.80
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Background Canine skin and eye diseases are common and can lead to serious health complications if not detected early. Limited access to veterinary care in remote areas further delays diagnosis and treatment. Aim This study aims to develop a mobile-based deep …
europepmc
2026
置信度 0.80
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Advancing neuroimaging modalities for motor cortex analysis is critical for understanding the neural mechanisms underlying fine motor tasks and for expanding clinical applications. Functional Near-Infrared Spectroscopy (fNIRS) is widely used for measuring cort…
europepmc
2026
置信度 0.80
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Modeling brain functional connectivity (FC) is key in investigating brain functions and dysfunctions. FC is typically quantified by symmetric positive definite (SPD) matrices that are located on a Riemannian manifold rather than the regular Euclidean space, wh…
europepmc
2025
置信度 0.80
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Background Multifocal non-invasive brain stimulation (NIBS) has been highlighted as a promising approach for modulating motor functions by simultaneously stimulating several brain areas. However, the effectiveness and underlying mechanisms of this technique ar…
europepmc
2026
置信度 0.80
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Accurate decoding of motor imagery electroencephalogram signals plays a critical role in brain-computer interfaces for neurorehabilitation and assistive technologies. However, existing multi-scale temporal methods often overlook scale-specific importance and f…
pubmed
Song Z, Zhang X
2026
置信度 0.82
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Recent advances in deep learning have enabled effective interpretation of neural activity patterns from electroencephalogram signals; however, challenges persist in invasive brain signals for cross-day neural decoding and simulation tasks. The inherent non-sta…
europepmc
2026
置信度 0.80
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pubmed
Zhang B, You X, Liu Y, Xu J 等
2026
置信度 0.82
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In motor imagery (MI) decoding, it still remains challenging to excavate enough contextual information of MI in different brain regions and to bridge the cross-session variance in feature distributions. In light of these issues, our study presents an innovativ…
europepmc
2025
置信度 0.80
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We present in this paper an implantable closed-loop neuromodulation prototype system for type 2 diabetes (T2D) management, which leverages pancreatic electrophysiology as both a sensing and therapeutic modality. Among candidate biomarkers, the fraction of plat…
europepmc
2026
置信度 0.80
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Introduction Deep brain stimulation (DBS) has been demonstrated to improve motor function by modulating brain circuits. However, the precise mechanism of action remains unclear. Existing DBS devices often lack suitability for rodent models, which are essential…
europepmc
2025
置信度 0.80
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Physiological artifacts pose persistent challenges in electroencephalogram (EEG) data acquisition, often compromising interpretation and post-analysis of EEG signals across research and clinical applications. To address such limitations, including various arti…
europepmc
2026
置信度 0.80
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We present the updated Enactive Torch (ET), an open-source, multimodal sensory substitution device engineered to facilitate synchronized haptic stimulation and neurophysiological data acquisition, particularly electroencephalography (EEG). Designed for modular…
europepmc
2026
置信度 0.80
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Neurotechnology is a rapidly emerging field with vast potential within healthcare, but also has inherent concerns. There is, therefore, a need to ensure the responsible and ethical development and regulation of these technologies. This horizon scan aimed to pr…
europepmc
2025
置信度 0.80
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This study presents BRAIN-META, a reproducible deep learning methodology designed for multi-class brain tumor classification using structural MRI. The proposed approach combines ten hybrid CNN-Vision Transformer (ViT) models with a meta-learning ensemble frame…
europepmc
2026
置信度 0.80
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Rapid serial visual presentation (RSVP) is a promising paradigm for visual brain-computer interfaces (BCIs) based on event-related potentials (ERPs) for patients with limited muscle and eye movement. This study explores the impact of video background and stimu…
europepmc
2026
置信度 0.80
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X-ray scanning diffraction can be used to raster-scan tissues to elucidate structural organization and other physical properties. A comprehensive data analysis package targeted to take raster X-ray diffraction (XRD) scans is vital in integrating data at multip…
europepmc
2026
置信度 0.80
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Real-time detection of motor intent using electroencephalography (EEG) with high accuracy remains a technical challenge for neurorehabilitation. Brain-computer interface-based neurofeedback training (BCI-NFT) paradigms need to detect pre-movement EEG to activa…
europepmc
2026
置信度 0.80
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Behavioral neuroscience relies heavily on controlled environments, such as operant chambers or "Skinner boxes," to characterize relationships between external stimuli and the resulting animal behavior. Increasingly, these methodologies are critical for the dev…
europepmc
2026
置信度 0.80
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Mobile eye-tracking has revolutionized the study of human behavior and cognition by enabling researchers to record eye movements in the real world. However, the dynamic and multimodal nature of mobile eye-tracking data also introduces significant analytical ch…
europepmc
2026
置信度 0.80
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Amyotrophic Lateral Sclerosis (ALS) is a rapidly progressive motor neuron disease that heavily impacts a person's ability to perform activities of daily living, affecting mobility, function, and communication drastically. These complications present a daunting…
europepmc
2026
置信度 0.80
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Intraoperative intracranial electrophysiological recordings provide unique access to human cortical dynamics but remain difficult to translate across patients due to inconsistent localization of transient surface electrodes. Unlike chronic implantations, intra…
pubmed
Rabbani H, Das I, Mandal AS, Nelson T 等
2026
置信度 0.82
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Individuals with ALS and other severe motor impairments often rely on caregivers for daily tasks, which limits their independence and sense of control. Brain-robot interfaces (BRIs) have the potential to restore autonomy, but many existing systems are task-spe…
europepmc
2025
置信度 0.80
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Hybrid Brain–Computer Interface (BCI) systems that combine electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) achieve higher classification accuracy but face computational bottlenecks due to the high dimensionality of the dat…
pubmed
Alhudhaif A
2026
置信度 0.82
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pubmed
Gan L, Yuan S, Guo M, Wang Q 等
2025
置信度 0.82
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Background Neuropathic pain (NP) is associated with maladaptive functional reorganization of the brain, yet the central mechanisms through which massage therapy exerts its analgesic effects remain poorly understood. This study aimed to investigate the impact o…
europepmc
2026
置信度 0.80
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This paper synthesizes ten years of experience from the Adolescent Brain Cognitive Development SM (ABCD) Study's Data Analysis, Informatics, & Resource Center (DAIRC), focusing on strategies for the collection, management, and release of data for a large, mult…
europepmc
2026
置信度 0.80
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Hydrogels are emerging as a transformative class of materials for bridging the interface between electronics and biological systems. Their softness, high water content, and tunable ionic/electronic conductivity enable conformal, low-impedance, and biocompatibl…
europepmc
2026
置信度 0.80
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Brain-on-a-chip (BOC) refers to a miniaturized in vitro platform that integrates living neuronal networks on a micro-engineered chip, enabling the simulation of brain functions, neural activities and physiological responses. BOC technology is an advanced evolu…
europepmc
2026
置信度 0.80
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Objective . existing steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) systems predominantly employ a flicker frequency range of 8-20 Hz, which often induces visual fatigue in users, thereby compromising system performance. Cons…
europepmc
2025
置信度 0.80
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The limitations of biohybrid and mechanical robots, including insufficient control accuracy, limited flexibility, long-term stability, and endurance, have spurred considerable research interest in cyborg animals, which leverage the innate locomotion capabiliti…
europepmc
2026
置信度 0.80
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Introduction Exoscopes are alternatives to operative microscopes in intraoperative visualization. Transitioning from microscope to exoscope demands new skills. Simulators are effective training tools in multiple fields, including surgery, yet no virtual simula…
europepmc
2026
置信度 0.80
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Objective . Seizure onset zone (SOZ) localization and SOZ resection outcome prediction are critical for the surgical treatment of drug-resistant epilepsy but have mainly relied on manual inspection of intracranial electroencephalography (iEEG) monitoring data,…
europepmc
2025
置信度 0.80
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Introduction To enhance flight performance and safety margins during the glide phase of carrier-based aircraft landing, this study systematically investigated the effects of integrated mental training on trainees' brain functional networks from four dimensions…
europepmc
2026
置信度 0.80
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The study of synchrony-concordant neural, physiological, and behavioral activity between individuals-has advanced our understanding of co-regulation and socio-emotional development, particularly within caregiver-child relationships. While previous research has…
europepmc
2026
置信度 0.80
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Background/objectives The transformer, introduced in 2017, has revolutionized several fields, including oncology. Its applications in cancer detection, diagnosis, prognosis prediction and treatment have shown significant potential. However, a comprehensive ana…
europepmc
2026
置信度 0.80
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Computational head models are essential tools for predicting the risk of mild traumatic brain injury (mTBI). However, computational models vary in the level of anatomical details, most notably the cortical folds. This study aims to determine the effect of mode…
europepmc
2026
置信度 0.80
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Introduction Visual electrophysiology, including electroretinograms (ERG) and visual evoked potentials (VEP), provides a real-time functional assessment of retinal and post-retinal pathways, complementing structural imaging. Subtypes such as transient, periodi…
europepmc
2026
置信度 0.80
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Artificial intelligence (AI), virtual reality (VR), gamification, and telerehabilitation are increasingly incorporated into neurorehabilitation to deliver adaptive, personalized, and remotely accessible interventions for individuals with stroke and other neuro…
europepmc
2026
置信度 0.80
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Background Brain tumor diagnosis from magnetic resonance imaging (MRI) remains a challenging task due to the high variability in tumor appearance and the limitations of manual interpretation. Methods To address these challenges, this paper proposes NeuroFusion…
europepmc
2026
置信度 0.80
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Error-related potentials (ErrPs) have been studied to evaluate wrong decisions or actions in several contexts. An ErrP is an electrical potential on the scalp generated by the perception of errors and occurs unwittingly. In human-robot collaboration (HRC), Err…
europepmc
2026
置信度 0.80
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This literature review critically examines the design, validation, and application of non-invasive in-ear electroencephalography (ear-EEG) systems as emerging wearable platforms for long-term neurophysiological monitoring and intervention. Following PRISMA gui…
europepmc
2026
置信度 0.80
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Objective To explore whether an AI-enhanced social robotic virtual patient (VP) platform reinforces empathetic behaviour patterns in medical students compared with a traditional computer-based platform. Methods Twenty-three sixth-semester medical students from…
europepmc
2026
置信度 0.80
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Mixed reality (MR) technologies enable users to experience computer-generated content within the physical environment through spatial computing and head-mounted displays. By supporting real-time interaction through speech, gesture, gaze, and movement, MR offer…
pubmed
Paranthaman PK, Bajaj N, LaMont L
2026
置信度 0.82
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Background Public discourse on "prompt engineering" has grown rapidly, but large-scale evidence on how people discuss it is limited. The nascent coinage describes a user journey of optimizing text-based parameters within large language models and generative AI…
europepmc
2026
置信度 0.80
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Brain-computer interface (BCI) offers a direct communication and control channel between the human brain and external devices, presenting new pathways for individuals with physical disabilities to operate robotic arms for complex tasks. However, achieving mult…
europepmc
2025
置信度 0.80
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Contemporary digital technologies reshape human deliberation through micro-targeting, persuasive design, and algorithmic systems capable of anticipating and steering behaviour. Cognitive autonomy thus emerges as a central legal value. The analysis of the Europ…
europepmc
2026
置信度 0.80
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Precise and synchronized multimodal data capture in neurosurgical environments is essential for further understanding brain function and will be crucial to advancing the development of brain-computer interface technology. We have developed an open-source softw…
europepmc
2026
置信度 0.80
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The study of the brain is a compelling example of the power of convergent science. Over the last few decades, advances in neuroscience techniques and experimentation, as well as in data science tools to analyze the resulting data, have dramatically furthered o…
europepmc
2026
置信度 0.80
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Bioelectronic Medicine relies on wearable or implantable electronic devices interfacing with the nervous system and other active tissues, offering innovative therapeutic solutions. However, the long-term reliability and stability of these devices remain critic…
europepmc
2025
置信度 0.80
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The rapid advancement of the Internet of Things (IoT), artificial intelligence (AI), and personalized healthcare has catalyzed an unprecedented demand for flexible and wearable sensor technologies [...].
europepmc
2026
置信度 0.80
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Primary cilia, microtubule-based sensory organelles that mediate cell-cell communication, may facilitate signaling in the brain through direct physical contacts (e.g., synapse-like structures). Similarly, specialized glial cells lining the third ventricle (3V)…
europepmc
2026
置信度 0.80
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Diffusion MRI fiber tractography is sensitive to noise and artifacts in diffusion-weighted images, and these challenges can propagate into fiber-orientation estimation and the tractography process. In this “Did You Know” communication, we synthesize evidence t…
europepmc
2026
置信度 0.80
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The behavioral inhibition system (BIS), mediating responses to punishment cues and avoidance behaviors, is implicated in anxiety. However, the neural dynamics underpinning BIS, particularly regarding the temporal variability of brain network interactions, rema…
europepmc
2026
置信度 0.80
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BackgroundWith the development of modern biomedical engineering, bio-signal feedback-based robots, such as electromyography (EMG)-based and brain-computer interface (BCI)-based rehabilitation robot, have emerged beyond conventional designs. However, their comp…
pubmed
Zhou L, Zhang B, Kang R, Wang Y 等
2025
置信度 0.82
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europepmc
2025
置信度 0.80
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Background Pathologic schizophrenia processes originate early in brain development, leading to detectable brain alterations via structural and functional magnetic resonance imaging (MRI). Recent MRI studies have sought to characterize disease effects from a br…
europepmc
2025
置信度 0.80
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Dry-electrode electroencephalography (dry-EEG) systems offer promising opportunities for real-time neurofeedback in naturalistic educational settings, yet their effectiveness in supporting complex language learning remains underexplored. This study investigate…
pubmed
Song K, Liu Y, Xu P
2025
置信度 0.82
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The pediatric brain represents a dynamic biological target characterized by rapid myelination and functional reorganization, which presents unique challenges for conventional, adult-centric artificial intelligence (AI) models. This review provides a structured…
europepmc
2026
置信度 0.80
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pubmed
Zhou S, Liu Y, Turnbull A, Tapparello C 等
2025
置信度 0.82
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The human brain is a complex adaptive system characterized by dynamic processes operating across multiple spatio-temporal scales. Capturing these dynamics requires computational models that can integrate different levels of resolution. In this work we present …
europepmc
2026
置信度 0.80
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Background: Upper-limb impairment is a major contributor to chronic disability after stroke. Conventional recovery protocols frequently suffer from poor adherence, limited accessibility, and insufficient intensity for prolonged rehabilitation. Methods: We perf…
europepmc
2026
置信度 0.80
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Electroencephalography (EEG) is a technique for measuring the brain's electrical activity in the form of action potentials with electrodes placed on the scalp. Because of its non-invasive nature and ease of use, the approach is becoming increasingly popular fo…
europepmc
2025
置信度 0.80
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Defence has a significant interest in the use of artificial intelligence (AI)-based technologies to address some of the challenges it faces. At the core of future military advantage will be the effective integration of humans and AI into human-machine teams (H…
europepmc
2025
置信度 0.80
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Laser therapy (860-910 nm) has been used to treat cancer since 1988. A key challenge is determining the dose of laser radiation absorbed by the tumor. Attenuation coefficients of laser radiation were determined for different breast tissues at various tissue th…
europepmc
2026
置信度 0.80
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Objective This study aims to conduct a bibliometric analysis of the application of brain- computer interface (BCI) in rehabilitation medicine, assessing the current state, developmental trends, and future potential of this field. By systematically analyzing re…
europepmc
2025
置信度 0.80
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It is essential to recognize the significant daily impact that post-stroke cognitive impairment (PSCI) has on patients and their families. Neuromodulation strategies have been increasingly applied in the clinical management of PSCI. This review outlines the me…
europepmc
2026
置信度 0.80
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Muscle myography encompasses a family of techniques for sensing muscle activity through its electrical, mechanical, and optical manifestations, offering non-invasive and embodied pathways for human-machine interaction. Unlike traditional input devices that are…
europepmc
2026
置信度 0.80
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BACKGROUND: Hand movement prediction enables the creation of personalized rehabilitation programs that align with individual neural patterns. It is particularly beneficial for patients recovering from strokes or other motor impairments, allowing therapists to …
europepmc
2026
置信度 0.80
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Current disease-sensing devices primarily focus on distinguishing between healthy and diseased states, effective for diagnosis but limited in guiding optimal intervention timing for prevention. We developed a tripartite framework identifying pre-disease state …
europepmc
2026
置信度 0.80
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This essay examines how Canadian copyright law treats neurodata generated for neuroprediction and further probes if copyright or similar protections would offer mechanisms to safeguard individuals who produce those data. Using a hypothetical fact pattern, we a…
europepmc
2026
置信度 0.80
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Background Artificial intelligence is expanding into telemedicine and telerehabilitation, yet significant privacy and security concerns persist. Scope To synthesize empirical evidence on privacy and security approaches in health care, particularly those releva…
europepmc
2026
置信度 0.80
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Endogenous bioelectric signals serve as pivotal physiological cues that govern cellular behavior and tissue regeneration. Conductive hydrogels have become a disruptive platform in the field of tissue engineering because they can promote tissue repair by utiliz…
europepmc
2026
置信度 0.80
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Here, we present a protocol for implementing scalable, modular hardware and software infrastructure to remotely operate programmable miniaturized networks of wireless neural devices in mice. We describe steps for fabricating remote control module (RCM) hardwar…
europepmc
2026
置信度 0.80
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Brain-computer interfaces (BCIs) have the potential to revolutionize communication for individuals with severe disabilities. EEG-to-text models, which translate brain signals into written language, offer a promising avenue for restoring communication abilities…
pubmed
Jo H, Yang Y, Han J, Duan Y 等
2025
置信度 0.82
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Numerous prior studies have shown that neural features can be voluntarily modulated through real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback (NF), and that such modulation can influence cognitive and affective states, as well as imp…
europepmc
2026
置信度 0.80
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Objective The purpose of this scoping review was to identify, geographically map, and understand what and how novel digital technologies are being used for providing cognitive training and psychosocial interventions that aim at preserving cognitive and everyda…
europepmc
2026
置信度 0.80
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New conceptual and technological developments bring neuroscientists closer to other disciplines and other fields in neuroscience with different traditions. Although some neuroscientists may underrate the potential benefits of successful interdisciplinary colla…
europepmc
2026
置信度 0.80
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Understanding how interactive digital art affects emotional states is essential to advance research into the interface between affective neuroscience and human-computer interaction. Although previous studies have used either EEG or self-reported measures to ev…
europepmc
2026
置信度 0.80
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Motor imagery training (MIT) is a widely used technique for motor learning and recovery. To optimize training outcomes, researchers have explored the integration of MIT with complementary approaches. One such approach is transcranial direct current stimulation…
pubmed
Bek J, Aziz A, Brady N
2025
置信度 0.82
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pubmed
Schopp L, Starke G, Ienca M
2026
置信度 0.82
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Tuberous sclerosis complex (TSC) is a multisystem genetic disorder. Neuropsychiatric manifestations (TSC-associated neuropsychiatric disorders [TAND]) are nearly universal and a key quality of life determinant but often overlooked.
pubmed
Zheng F, Yu T, Salim Ahmad I, Zhao X 等
2026 Aug
置信度 0.82
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The quality of stable long-term recordings from chronically implanted electrode arrays is essential for experimental neuroscience and brain-computer interfaces. This work uses scanning electron microscopy (SEM) to image and analyze eight 96-channel Utah arrays…
pubmed
Tor A, Clarke SE, Bray IE, Nuyujukian P 等
2026 Jun 19
置信度 0.82
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Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant neurodegenerative disorder characterized by misfolded ataxin-3 aggregation and neuronal intranuclear inclusions. Its primary symptom is progressive ataxia, progressively r…
pubmed
Chen LW, Lian YH, Dong XL, Luo KL 等
2026 May 25
置信度 0.82
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This work presents a multimodal dataset containing synchronized electroencephalography (EEG), electromyography (EMG), and kinematic recordings acquired during wrist motor tasks performed with a three degree of freedom robotic exoskeleton (BiomechWrist) coupled…
pubmed
Perez-Blanco JG, Huegel JC, Hernández-Rojas LG, Valdez-Calderón A 等
2026 Apr 22
置信度 0.82
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The role of brain network dynamics in relation to amyloid beta (Aβ) and tau pathology across Braak stages remains unclear.
pubmed
Li J, Yi Y, Gan L, Bezgin G 等
2026 Apr
置信度 0.82
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In the neurorehabilitation framework of treadmill-based robot-assisted gait training (t-RAGT), a threefold relationship among physiotherapist (Pht), patient (Pt), and the selected robotic device should be considered. Furthermore, the type of visual FeedBack (F…
pubmed
Toppi J, Pichiorri F, Ciaramidaro A, Mohebban S 等
2026 Mar 24
置信度 0.82
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Steady state visually evoked potentials (SSVEPs) are a popular type of control signals in brain-computer interfaces (BCIs), in which they are typically elicited by observing a visual stimulus flashing at a specific frequency. For some patients, using SSVEP as …
pubmed
Priori S, Ricci P, Consoli D, Micheli A 等
2026 Mar 4
置信度 0.82
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Accurate diagnosis and monitoring of recovery after stroke are critical for effective motor rehabilitation. As stroke is inherently associated with impaired cerebral blood flow, functional near-infrared spectroscopy (fNIRS) provides a valuable tool for assessi…
pubmed
Medvedeva A, Syrov N, Yakovlev L, Alieva Y 等
2026 Feb 14
置信度 0.82
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Individuals with significant communication and physical impairments often rely on augmentative and alternative communication (AAC) to facilitate independent communication across a range of communication partners and settings. Due to physical impairments, many …
pubmed
Murphy A, Schaly S, Chiu D, Mitchell A 等
2026 Feb 6
置信度 0.82
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Hyperactivity is a well-documented neurobehavioral effect of morphine and other opioid drugs, predominantly observed in rodent models, yet the neural circuits and molecular mechanisms underlying this effect remain elusive. In this study, an excitatory projecti…
pubmed
Li CY, Huang H, Shen XF, Cao KL 等
2026 Feb
置信度 0.82
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Objective. Despite decades of electroencephalography (EEG) research, the relationship between EEG and underlying spiking dynamics remains unclear. This limits our ability to infer neural dynamics reflected in intracranial signals from EEG, a critical step to b…
pubmed
Sharma D, Krekelberg B
2025 Dec 19
置信度 0.82