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• Distributed Brain Hypothesis: A Brain, Maybe, Bigger than We Though
  The dominant view in neuroscience treats the brain as the primary computational organ of cognition and emotion, with the peripheral nervous system supplying sensory input and executing motor and autonomic commands. Embodied and interoceptive theories acknowled…
  preprints 2026 置信度 0.74
• On Breathing Variability in the Tree Shrew
  Tree shrews ( Tupaia belangeri ) are increasingly used in comparative neuroscience, yet their respiratory physiology remains poorly characterized. We quantified spontaneous breathing and respiratory rhythm variability in awake adult tree shrews (n = 10; 5 male…
  preprints 2026 置信度 0.74
• ‘For Your Brain’: Neural connectivity tracks perceived personalization success of the TikTok algorithm
  Personalized recommender algorithms are among the most influential design features of modern digital platforms. Yet, most neuroscience research on social media relies on controlled stimuli sets, or associating behaviors with general neuroimaging tasks; these m…
  preprints 2026 置信度 0.74
• The Architecture of Sovereign Narrative Therapy (SNT): A Predictive Processing Framework for Symbolic Reorganization and Narrative Identity Revision
  Background: Narrative and psychodynamic therapies have long emphasized the therapeutic value of metaphor, imagery, embodiment, and symbolic enactment. However, the mechanisms through which these processes contribute to enduring identity-level change remain inc…
  preprints 2026 置信度 0.74
• Neurocognitive Foundations of Adaptive Behavior in Partially Observable Environments
  Adaptive behavior requires acting on sensory evidence that only partially reveals relevant environmental states. Partially observable Markov decision processes (POMDPs) provide a unified framework for this problem by representing perceptual uncertainty as beli…
  preprints 2026 置信度 0.74
• Magnitude Without Direction: A Representational Limit on the General Factor of Psychopathology
  The general factor of psychopathology, p, orders people on a broad dimension of psychiatric burden and predicts impairment, developmental risk, and other adverse outcomes. Debate has focused on which latent-variable structure best recovers p, but comparative f…
  preprints 2026 置信度 0.74
• An organotypic neocortical slice culture for studying neuroglial interactions
  Organotypic slice cultures (OSCs) are widely used to study cellular properties in a functional and developmental tissue context. With the recent advent of transgenic mouse lines and viral tools we postulated that OSCs may enable the study of multicellular glia…
  preprints 2026 置信度 0.74
• Emotion Representation and Neural Synchrony: Decoding Valence and Arousal with Wearable EEG
  Emotions are dynamic experiences that unfold over time, yet most affective neuroscience studies have relied on static stimuli and laboratory-based EEG systems. This study examined whether emotional valence and arousal can be reliably decoded using a consumer-g…
  preprints 2026 置信度 0.74
• The Meridian-Program Hypothesis: Rethinking the Acupuncture System as a Bioelectrical Control and Information Network
  Acupuncture is supported by a long clinical tradition and a growing body of mechanistic research, yet the classical meridian system remains difficult to reconcile with conventional anatomical models. The persistent difficulty may arise from a category error: m…
  preprints 2026 置信度 0.74
• Generalisable signatures of anaesthesia in the large-scale functional organisation of the marmoset brain
  How the activity and connectivity of the brain support consciousness remains a central question in neuroscience. Recent progress driven by the use of functional MRI has seen growing recognition that large-scale distributed functional organisation of the human …
  preprints 2026 置信度 0.74
• Listening Difficulties and the Maturation of the Central Auditory Nervous System – A Narrative Review
  The following review is an integration and synthesis of a subset of the central auditory nervous system (CANS) and auditory processing (AP) literature of the last 25 years. It encompasses many different aspects of AP, and aims to contribute to an auditory neur…
  preprints 2026 置信度 0.74
• Precisely Sculpting Complex Attractor Landscapes through Topological Design - A Resource-Conserving Share-and-Plunder Graph Dynamical Equation
  Abstract Attractor models in neuroscience and cognitive dynamics sometimes use deliberately designed topology to produce discrete choices, continuous manifolds, memory states, or temporal patterns. These examples show that topology can shape the attractor land…
  preprints 2026 置信度 0.74
• Sensorimotor recovery and neuropathic pain reduction after remotely delivered cognitive multisensory rehabilitation or remotely delivered exercise in adults with spinal cord injury: a pilot clinical trial
  Introduction Reduced or lost sensation and movement after a spinal cord injury (SCI) impairs the brain’s ability to accurately localize paralyzed body parts, causing deficits in its internal body map, or “mental body representations” (MBR). These deficits hind…
  preprints 2026 置信度 0.74
• Reconciling principles of cortical organisation: A historical review of areas and gradients
  A debate is raging in human neuroscience over the foundational principles of cortical organisation, chiefly whether the cortex is best characterised by discrete areas or continuous gradients. Though fuelled by recent insights from in vivo neuroimaging, the deb…
  preprints 2026 置信度 0.74
• The Neuroscience of Marketing: Noninvasive Neuromarketing Methods for Understanding Consumer Choice and Priorities
  preprints 2026 置信度 0.74
• Spectral Basis Interpretable Unit: A Learned Orthogonal Projection Module for Interpretable Function Approximation and Unsupervised Regime Discovery
  Abstract We introduce the Spectral Basis Interpretable Unit (SBIU)—a univariate function approximator that maps a scalar input to a probability distribution over a learned orthogonal set of basis vectors in a Fourier-encoded feature space. The output is a weig…
  preprints 2026 置信度 0.74
• A Phase 2b randomized clinical trial of the oral p38α inhibitor neflamapimod in dementia with Lewy bodies (DLB)
  Abstract Background: There is high unmet need in dementia with Lewy bodies (DLB). Neflamapimod, showed clinical activity against cognitive and motor endpoints at a dose of 40mg three-times-daily (TID) in a prior phase 2a study in DLB, most prominently in those…
  preprints 2026 置信度 0.74
• ZeroES: A Practical Implementation of the Zero Pairs Interaction Functional – Zigzag Zero–Fractional Zero Framework for Prime Analysis, Market Forecasting, and Neural Signal Processing
  This work presents ZeroES (Zero Ebrahim Elsayed), the first comprehensive practical implementation of the Zero Pairs Interaction Functional – Unified Spectral Alignment and Coherence – Zigzag Zero–Fractional Zero (ZPIF-USAC-ZZFZ) framework. ZeroES is a multi-d…
  preprints 2026 置信度 0.74
• Viewpoint on Functional Coupling and Neural Oscillations in Multisensory Integration
  In this viewpoint article, Jennifer Bizley and Daniel Senkowski share their perspectives on past, present, and future developments in research on the roles of functional coupling and neural oscillations in multisensory integration. Drawing on existing studies,…
  preprints 2026 置信度 0.74
• Cognitive Feelings from Healthy Experience to Psychopathology: An Integrative Review Across Phenomenology, Psychology, Neuroscience, and Computation
  Cognitive feelings, such as the feeling of knowing, familiarity, presence, reality, confidence, agency, and body ownership, are subjective experiences arising from cognitive processes, playing crucial roles in perception, memory, and decision-making. Despite e…
  preprints 2026 置信度 0.74
• A Structural Principle for Macroscopic Neural Dynamics Correlations
  A central question in neuroscience is how the brain’s structural connectivity gives rise to its emergent, correlated dynamics. These large-scale dynamical correlations underlie functional networks that support cognitive functions. Here, we identify coupling co…
  preprints 2026 置信度 0.74
• Why response inhibition research presents unique challenges for unimodal BOLD-fMRI
  Response inhibition is one of the most important control processes in the human brain. The study of the basic neural mechanism(s) underlying response inhibition has produced some of the most-cited empirical work in cognitive neuroscience to date, with a large …
  preprints 2026 置信度 0.74
• Ethical considerations for integrating social determinants in brain health research: A cultural-ecosocial approach
  The integration of social determinants of health (SDH) into neuroscience and brain health research is a critical step in advancing our understanding of the complex interplay between social environments and neurobiological outcomes. However, this integration ra…
  preprints 2026 置信度 0.74
• From microstates to macroscales: A Critical Review of Maximum Entropy Modeling and Energy Landscape Analysis in functional MRI
  Abstract Functional magnetic resonance imaging has revolutionized neuroscience. Traditional analyses focusing on differences in regional activations and pairwise regional interactions (functional connectivity) cannot capture the collective nature of inherently…
  preprints 2026 置信度 0.74
• THE MANUAL TRIGGER FALLACY
  Contemporary personal safety tools, including emergency SOS buttons, panic applications and distress call features, share a foundational design assumption: that a person under threat retains the cognitive capacity and motor control necessary to activate a manu…
  preprints 2026 置信度 0.74
• Bringing Attention to Education: Revisiting the Neural Mechanisms of Selective Attention in Naturalistic Learning
  In the context of education, attention can be considered the gateway for learning. Cortical attention mechanisms may help explain, in a precise and mechanistic manner, crucial educational modulators that are essential to effective learning and relevant to cons…
  preprints 2026 置信度 0.74
• Interbrain synchrony analysis for fNIRS – a signal processing primer
  Interbrain synchrony (IBS), also referred to as interpersonal neural synchrony (INS), has become a central construct in social neuroscience and beyond. It describes the temporal alignment of neural activity across individuals and has been studied in a range of…
  preprints 2026 置信度 0.74
• A Polarized Histamine-GABA Core-Rim Architecture within Synaptic Vesicles
  Neuroscience traditionally assumes that amino acid transmitters occupy clear synaptic vesicles, whereas monoamines reside in dense-core vesicles. Using a glutaraldehyde–NaBH₄ epitope-engineering platform enabling ultrastructural detection of small amines, we i…
  preprints 2026 置信度 0.74
• From Psychology and Neuroscience to AI: Toward a Learning-Based Computational Theory of Mind Model
  Despite the dramatic advances made in artificial intelligence (AI) and other fields of computer science towards implementing “intelligent” systems expert in specific tasks, the goal of devising algorithms and machines able to interact with human beings just as…
  preprints 2026 置信度 0.74
• Computational and causal dissociation in primate striatum during value-guided decision-making
  How neural representations carrying similar information across brain regions are translated into behavioral control remains a fundamental question in neuroscience. In the primate striatum, whether subregions make overlapping or dissociable computational and ca…
  preprints 2026 置信度 0.74
• How attentional states shape interpersonal physiological synchrony: current evidence and a mechanistic model
  Interpersonal physiological synchrony (IPS), the temporal alignment of autonomic signals across individuals, has been documented across a wide range of contexts, both during reciprocal social interactions—here referred to as reciprocal IPS (R-IPS)—and when ind…
  preprints 2026 置信度 0.74
• Addiction as a Chronic Brain Disease: A Narrative Review of the Neurobiological Evidence
  Addiction has traditionally been explained in moral terms, as a failure of discipline repeated onetoo many times. Three decades of neuroscience research complicate that story considerably.Repeated exposure to alcohol and other drugs changes how the brain's rew…
  preprints 2026 置信度 0.74
• Neurobiological Underpinnings of NDPS Drug Dependence and Their Role in Antisocial and Criminal Behaviour: A Multidisciplinary Review
  Abstract Substance use disorders, specifically drug abuse/dependence involving controlled substances covered under the Narcotic Drugs and Psychotropic Substances (NDPS) Act, 1985, have become one of the primary issues of public health and forensic importance i…
  preprints 2026 置信度 0.74
• Circuit-specific reorganization of hippocampal-entorhinal-prefrontal subnetworks supports memory recall across the lifespan
  How memories reorganize across brain circuits as they age remains a central question in systems neuroscience. Systems consolidation is thought to progressively shift memory reliance from the hippocampus to distributed cortical networks, yet the contribution of…
  preprints 2026 置信度 0.74
• Simultaneous brain-wide single-cell recording resolves spatiotemporal memory architecture
  Many fundamental mammalian brain functions emerge from the coordinated activity of cells distributed across large, brain-wide networks. To understand these processes in healthy and diseased states, ideally one would simultaneously measure and analyze single-ce…
  preprints 2026 置信度 0.74
• A Scalable Cross-Modal Workflow for Linking In Vivo Neural Activity to Neuronal Cell Types via Spatial Gene Profiling
  SUMMARY A central challenge in systems neuroscience research is to elucidate how distinct neuronal cell types coordinate to produce complex behaviors: an endeavor that requires linking their molecular identity, connectivity and activity patterns in behaving an…
  preprints 2026 置信度 0.74
• Self-Supervised Multi-Modal Transformer for Early Brain Tumor Prediction Using Super-Resolution MRI and ICU Time-Series Data
  Abstract Early and accurate detection of brain tumors remains one of the most challenging and consequential problems in clinical neuroscience and critical care medicine. Conventional diagnostic pipelines rely heavily on expert radiological interpretation of si…
  preprints 2026 置信度 0.74
• Mismatch Negativity and General Cognitive Ability - A Meta-Analysis
  Intelligence or general cognitive ability (GCA) is fundamental to human behavior and cognition. It impacts important life outcomes like educational success and even health and longevity have been related to differences in GCA. Understanding the biological basi…
  preprints 2026 置信度 0.74
• Astrocyte-Selective Wireless Deep Brain Stimulation by Magnetite Nanodiscs at Low Alternating Magnetic Field
  Astrocytes are essential regulators of synaptic transmission, brain homeostasis and behavior, and direct astrocyte activation has emerged as a therapeutic target for a broad range of neurological disorders. However, selective activation of astrocytes in vivo c…
  preprints 2026 置信度 0.74
• Cardio-respiratory modulation of arousal and excitability states
  The field of interoception research is currently working towards an understanding of how brain-body states determine human perception, cognition, and behaviour. Recent studies suggest that transient dynamics of arousal neuromodulation and cortical excitability…
  preprints 2026 置信度 0.74
• Convolutional Neural Networks & Neuroscience: A Tutorial Introduction for The Rest of Us
  Convolutional neural networks (CNNs) are a class of artificial neural networks (ANNs). Since the early 2010s, they have been widely adopted as models of primate vision and classifiers of neuroimaging data, becoming relevant for a wealth of neuroscientific fiel…
  preprints 2026 置信度 0.74
• Closed-loop optical optimization enables patterned retinal stimulation <i>in vivo</i> at cellular scales
  Visual neuroscience requires precise spatiotemporal projection of optical stimulation onto the retina, especially in experimental mouse models. However, in vivo patterned stimulation in mice is profoundly hindered by the extreme optical power and severe anatom…
  preprints 2026 置信度 0.74
• USAC: Unified Spectral Alignment & Coherence Framework – A New Mathematical Paradigm for Prime Gaps, Dark Energy, Neural Dynamics, and Spacetime Geometry
  This work introduces the Unified Spectral Alignment Coherence Framework (USAC), a new mathematical framework that uncovers deep connections between prime gaps, dark energy, neural dynamics, and spacetime geometry. At the heart of this framework lies a simple y…
  preprints 2026 置信度 0.74
• Geometric constraints and cognitive inputs jointly shape emergent brain dynamics and topology
  How the brain's physical geometry gives rise to its flexible functional repertoire remains a central question in neuroscience. Here, we trained three classes of recurrent neural networks (RNNs) on a working-memory task, forming a graded hierarchy of spatial co…
  preprints 2026 置信度 0.74
• Reduced option generation reveals distinct profiles of apathy in schizophrenia
  Apathy is a major driver of long-term disability in schizophrenia, yet existing accounts focus on how patients evaluate the cost of action while neglecting their capacity to generate options for action in the first place. Using a brief, culture-fair option gen…
  preprints 2026 置信度 0.74
• Robust circular cluster-based statistics for respiration-brain coupling
  The rapidly developing research field of brain-body neuroscience faces methodological challenges, as analysts continue to develop new analysis strategies for robust statistics in the absence of established best practices. This quest for robust statistics is fu…
  preprints 2026 置信度 0.74
• Trade-off between performance and human-like perception in face recognition models
  Deep learning models for face recognition are widely adopted in cognitive neuroscience, yet it is not well understood whether their excellent performance means they “see” faces like humans. Here, we collected a substantial dataset of human face-similarity judg…
  preprints 2026 置信度 0.74
• Ecology of curiosity framework for adaptive and maladaptive human–AI ecosystems
  Human intrinsic curiosity evolved under constraints of time, effort, and risk. Understanding how it is regulated, and harnessing it for well-being and for adaptive agentic artificial intelligence (AI), requires considering the environments in which uncertainty…
  preprints 2026 置信度 0.74
• Oscillatory Hierarchical Reservoirs for Human-like Rhythm Perception and Anticipation
  Abstract Rhythm is a fundamental aspect of human behaviour, present from infancy and deeply embedded in cultural practices. Rhythm anticipation is a spontaneous cognitive process that typically occurs before the onset of actual beats. While most research in bo…
  preprints 2026 置信度 0.74
• Attention in laboratory tasks versus naturalistic learning contexts: Heterogeneity in measurement and mechanisms
  Abstract An important though less studied element in neuroscience of classroom learning, is translation of laboratory-derived metrics to quantify learning in naturalistic settings. In the current study we sought to test if a common neural metric of visual atte…
  preprints 2026 置信度 0.74
• Routing by Hurst: Matching Decomposed Modes to Inductive Biases for Time-Series Learning
  Abstract Abstract—Real-world time series superimpose persistent trends and transient flfluctuations whose statistical characters differ markedly. Systems neuroscience documents that the primate cortex handles such multi-scale input through a hierarchy of intri…
  preprints 2026 置信度 0.74
• Healthy Aging as Information Divergence in the Multiplex Brain
  A bstract Understanding the co-evolution of the human brain’s structural scaffold and functional traffic across the adult lifespan remains a fundamental challenge in neuroscience. While age-related degradation in grey matter and functional activation is well-d…
  preprints 2026 置信度 0.74
• Neural Signatures of Conscious Experience During Sleep: A Serial Awakening Study Using High-Density EEG
  Identifying neural signatures of consciousness remains a central challenge in neuroscience. Sleep offers a tractable model for comparing brain activity in the presence or absence of subjective experience while minimizing behavioral responsiveness confounds. Us…
  preprints 2026 置信度 0.74
• Toward defining loss functions in neuroscience: an XOR-based neuronal mechanism
  A bstract One of the most compelling ideas for bridging neuroscience and artificial neural networks is the establishment of a framework based on three main components: network architecture, optimization mechanism, and loss (or objective) function to be minimiz…
  preprints 2026 置信度 0.74
• Blood-Mediated Opto-Acoustic Stimulation of Brain Cortex at Sub-millimeter Precision
  Direct modulation of neural activity with high spatiotemporal precision is a cornerstone in experimental neuroscience. Here, we present a blood-mediated optoacoustic stimulation (BOAS) approach that utilizes blood as an endogenous transducer for brain stimulat…
  preprints 2026 置信度 0.74
• A Mechanical Theory for the Formation of Short Association Fibers in the Brain
  The development of neural connections in the brain results from a complex interplay between biological processes and mechanical forces. A key question in neuroscience is how physical forces and the mechanical properties of brain tissue influence the formation …
  preprints 2026 置信度 0.74
• Multimodal Topological Characterization of Dynamic Causal Networks in Multivariate Time Series
  (1) Background: Characterizing causal structures in multivariate time series is a central challenge across neuroscience, economics, and environmental sciences; classical estimators identify which causal relations exist but lack compact descriptors capable of d…
  preprints 2026 置信度 0.74
• Shared Neurobiological and Computational Mechanisms of Psychedelic, Contemplative, and Fasting-Induced Mystical Experience
  Psychedelics, contemplative practice, and fasting are physiologically unrelated interventions that nevertheless converge, across cultures and centuries, on a common experiential endpoint: the mystical state. Here I propose that this convergence reflects shared…
  preprints 2026 置信度 0.74
• A transparent miniscope-integrated ultrasound platform enables concurrent focused neuromodulation and wide-field imaging in freely moving mice
  Abstract Simultaneous ultrasound stimulation and optical imaging in freely behaving animals remains challenging because existing systems are often bulky, incompatible with optical readout, or used in paradigms in which stimulation and recording are temporally …
  preprints 2026 置信度 0.74
• Emergent E-I Structure in Performance-Evolved Reservoir Networks of Neuronal Population Dynamics
  Abstract Understanding how network structure emerges from functional demands is a central principle in network physiology and computational neuroscience. A key question remains whether compact computational models can recover the \textit{structure-function} co…
  preprints 2026 置信度 0.74
• Bridging Rodent and Human Cognition: A Framework for Translational Cognitive Assessment in Brain Disorders
  Neurocognitive dysfunction is a core feature of psychiatric, neurodegenerative, and addictive disorders, exerting a profound impact on functional outcome, quality of life, and long-term prognosis. Across conditions, impairments in learning, memory, attention, …
  preprints 2026 置信度 0.74
• Ontological literacy: a pragmatic framework to foster ontological diversity in policy, research and education
  Background: Policy, research, and education in the EU rely on secular-scientific ontologies, creating an “ontological blindness” that excludes diverse worldviews and more-than-human agency. Current scholarship lacks practical tools to operationalize ontology i…
  preprints 2026 置信度 0.74
• Seeing at Will: Shared Neural Representations of Motion Perception and Intention
  Volitional intention can bias perception in cases where two or more interpretations of a stimulus are available to us. The neural mechanisms whereby such an intention influences perception are poorly understood. Here we investigated whether intending to see ho…
  preprints 2026 置信度 0.74
• ZPIF (Zero Pair Interaction Functional): A Proposed Quadratic Spectral Framework for Unifying Prime Distribution, Dark Energy, Quantum Consciousness, and Spacetime Structure
  We introduce \textbf{ZPIF (Zero Pair Interaction Functional)} as a quadratic spectral framework that explores potential connections between four fundamental puzzles: prime gaps, dark energy, consciousness, and spacetime structure. Departing from classical line…
  preprints 2026 置信度 0.74
• Sub-lethal imidacloprid exposure leads to presynaptic and postsynaptic alterations
  Abstract Pesticides are commonly used in agriculture to mitigate a wide array of pests. Imidacloprid, the most frequently used neonicotinoid pesticide, has been reported to affect cholinergic signaling of off-target organisms, such as honey bees and nematodes.…
  preprints 2026 置信度 0.74
• Selectivity for high-level language processing is highly localized in individual brains
  Some aspects of human behavior and cognition depend on focal and selective cortical areas, such as the frontal eye fields or fusiform face area, while others, like semantic knowledge, are broadly distributed across the cortex. Whether higher-level cognitive fu…
  preprints 2026 置信度 0.74
• Individual Differences in Second Language Word Learning: Toward a Neurocognitive Model of Vocabulary Learning Capacity
  Vocabulary acquisition in a second language (L2) is a complex, multifactorial process shaped by individual differences in cognitive, linguistic, and motivational capacities. This paper introduces the Word Learning Capacity Model (WLCM), a developmental and neu…
  preprints 2026 置信度 0.74
• Using Latent Chemical Recognition in an Evolved Periplasmic Binding Protein Family to Diversify Biosensors
  Genetically encoded fluorescent biosensors have gained traction in neuroscience as continuous, reagentless reporters of cellular activity in situ . These sensors, often soluble, can also provide time-resolution in multiple biosensing form factors: benchtop and…
  preprints 2026 置信度 0.74
• E2IATLAS: A Normative Database of Nature Images with Affective and Self-Transcendent Emotion Ratings
  Abstract We introduce the Eco-Emotion Image ATLAS (E2IATLAS), a normative database of 3,161 nature photographs rated by 2,092 participants from 52 countries on six affective dimensions: valence, arousal, awe, compassion, connectedness, and gratitude. Images we…
  preprints 2026 置信度 0.74
• Causal Mapping of Bodily Awareness and Mesoscale Circuit Organization in the Human Cingulate and Precuneus
  Abstract How the human brain generates subjective bodily experience remains a fundamental question in cognitive neuroscience. The cingulate cortex and precuneus (CC/PCu) have been implicated in bodily awareness and self-related processing, yet the functional a…
  preprints 2026 置信度 0.74
• Prepping for School: Parent–Child Neural Synchrony During Guided Preschool Learning Tasks
  The preschool years are crucial for school readiness, with the child-parent attachment relationship providing a foundational context for skill acquisition as part of this transition. Advances in social neuroscience suggest that interpersonal neural synchrony (…
  preprints 2026 置信度 0.74
• Critical review on the development and evolution of beat perception
  Beat perception—the ability to extract a regular pulse from rhythmic sequences—is a foundational component of human musicality and a key mechanism supporting synchronization, dance, and collective music-making. Research across neuroscience, developmental psych…
  preprints 2026 置信度 0.74
• Causal Discovery of Synchronous Neural Oscillations based on Jacobian-informed VAR-LiNGAM
  The primary objective of system neuroscience is to understand the functional mapping and its causation in the dynamics of the brain network. Some experimental and methodological studies suggest that functional modularity and its hierarchical information proces…
  preprints 2026 置信度 0.74
• The recipe for intelligence in natural and artificial systems
  Ten years ago, two landmark papers discussed open problems in AI research from the standpoint of neuroscience and cognitive science. Today, many of these problems have been solved, mostly without direct inspiration from the study of the human brain. In this pa…
  preprints 2026 置信度 0.74
• The cost of scrutiny: subclinical social anxiety and performance context reshape frontal-midline theta network reconfigurations during probabilistic learning
  Social anxiety is reliably characterized by biases toward avoidance and aversive learning. Frontal-midline theta (FM-theta) oscillations have been implicated as a key neural mechanism underlying these learning biases. Here we combined a dynamic network neurosc…
  preprints 2026 置信度 0.74
• Whole-brain modeling of dynamic causal circuits in human cognition using amortized variational inference
  ABSTRACT Understanding dynamic mechanisms underlying cognition remains a major challenge in human neuroscience. Here, we develop, validate, and apply Multivariate Dynamical Systems Identification with Amortized Variational Inference (MDSI-AVI), a novel computa…
  preprints 2026 置信度 0.74
• From Scalp to Source: Precise Phase Retrieval of Intracerebral Epileptic Sources Based on Surface EEG
  Accurate phase tracking of deep-brain activity is critical for effective closed-loop and phase-locked neuromodulation therapies. However, direct access to deep neural phase through intracranial recordings remains clinically restrictive due to the invasiveness.…
  preprints 2026 置信度 0.74
• Stable brain architecture but flexible dynamics: distinct structure - function coupling signatures link aging and genetic Alzheimer's risk to cognitive decline in 34,067 adults
  Abstract Understanding how a stable structural connectome supports flexible cognition, especially in aging, is a fundamental question in neuroscience. While static structure-function coupling (SFC) is well-studied, the temporal variability of structure-functio…
  preprints 2026 置信度 0.74
• Word-Level Measures of Syntactic Complexity in Sentence Processing: An Organizing Review
  The recent adoption of naturalistic paradigms in the psychology and neuroscience of language has necessitated methods for quantifying incremental syntactic processing complexity. However, there is little consensus about how complexity should be quantified. Exi…
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• Capacity Limits in Cognitive Processing Reflect the Curse of Generalization
  The striking constraints of some human cognitive processes stand in stark contrastto the near limitless capability of others. While we can acquire and flexibly use vast amountsof information, the amount we can process at any one time is often stiflingly limite…
  preprints 2026 置信度 0.74
• An Integrated EEG, TMS-EEG and Behavioural Dataset for Investigating the Neural Correlates of Working Memory
  Working memory is a fundamental process that underlies cognition. Accordingly, the neural mechanisms that support working memory performance are of great interest in cognitive neuroscience. We present a publicly accessible dataset comprising 123 healthy adults…
  preprints 2026 置信度 0.74
• Neural correlates of the subjective experience of free-will during value-based risky decisions: a pilot study
  ABSTRACT Underlying the very notion of choice is the fundamental idea of ‘free-will’, which is challenged by decision-neuroscience aiming to explain and predict choices using interactions of neurons. The question of whether any choice is truly a free-choice an…
  preprints 2026 置信度 0.74
• NeuroLab OS: A local-first software environment for scientist-reviewed neural time-series modelling and provenance-aware simulation
  Abstract Background and Objective: Reproducible neural time-series analysis re- quires more than preserving code: the scientific interpretation also depends on the exact preprocessing choices, model equations, parameter semantics, numerical settings, random se…
  preprints 2026 置信度 0.74
• BCCWJ-Brain: A Multi-Modal fMRI, MEG, and EEG Dataset of Naturalistic Japanese Reading
  We present the BCCWJ-Brain dataset, a multi-modal neuroimaging resource comprising functional magnetic resonance imaging (fMRI), magnetoencephalography (MEG), and electroencephalography (EEG) data recorded from native Japanese speakers reading newspaper articl…
  preprints 2026 置信度 0.74
• Supporting children with special educational needs and disabilities in schools: Critical insights from Educational Neuroscience
  Special Educational Needs and Disabilities (SEND) encompass heterogeneous learning profiles that require additional support in schools. This paper draws on evidence from educational neuroscience to explore how best to support students with SEND. We highlight t…
  preprints 2026 置信度 0.74
• Static Stretching as a Multilevel Mechanobiological Process: An Integrative Framework from Mechanical Loading to Biological Adaptation
  Static stretching is one of the most widely prescribed interventions in sports medicine, rehabilitation, and exercise science for improving joint range of motion (ROM) and flexibility. Despite decades of research, however, the biological mechanisms underlying …
  preprints 2026 置信度 0.74
• The physiological dynamic clamp allows insect flight muscle to transition between two actuation modes in virtual reality
  In most muscles, contraction is initiated by neural activation. Some groups of insects break this rule, flapping at frequencies far exceeding the neural drive to their flight muscles. These insects’ muscles (termed asynchronous) produce force in response to st…
  preprints 2026 置信度 0.74
• Investigating the longevity of real-world memory following a smartphone intervention in older adults: A multi-year follow-up study
  Our ability to recollect details from personal past events tends to decline with age, which can affect how we act in the world, communicate with others, and understand ourselves. HippoCamera is a neuroscience-guided smartphone application that aims to mitigate…
  preprints 2026 置信度 0.74
• EEG microstates under naturalistic movie-watching: dissociating state and trait empathy with links to prosocial behavior
  Abstract Traditional empathy neuroscience relies heavily on static and repetitive stimuli, which limits the characterization of neural dynamics in naturalistic contexts. Whether EEG microstate analysis, a method applied predominantly in resting-state and clini…
  preprints 2026 置信度 0.74
• Laterality of subcortical structures predicts spontaneous brain dynamics
  Subcortical structures play a key role in shaping cortical computation through distributed cortico-subcortical networks, yet it remains unclear whether individual differences in subcortical anatomy are reflected in resting-state cortical oscillations. We analy…
  preprints 2026 置信度 0.74
• Neuro-AI for Sports: Brainwave-Informed Performance Prediction Using Deep Learning and EEG Analysis
  Abstract Neuroscience and artificial intelligence, the convergence of neuroscience and artificial intelligence has presented revolutionary sports performance optimization. This paper is a comprehensive Neuro. The AI system based on electroencephalography (EEG)…
  preprints 2026 置信度 0.74
• Capturing the developing brain in motion: A practical tutorial for recording mobile EEG in naturally moving children
  This tutorial seeks to facilitate the use of mobile electroencephalography (EEG) in young children. Mobile EEG allows researchers to investigate neural correlates of behavioral and cognitive processes in ecologically valid settings. While mobile EEG has been w…
  preprints 2026 置信度 0.74
• The Sensation Modulating Network: Haltability as the architectural ground for object-directed phenomenology
  We propose the Sensation Modulating Network (SMN): the cognitive agent conceived as the whole body, organized at every anatomical scale by opponent dynamics, built from Sensation Modulators — tissue that senses and acts through one substrate — paired into Coor…
  preprints 2026 置信度 0.74
• A predictive theory of experimental design for inferring neural population geometry in large-scale recordings
  SUMMARY Ongoing technological advances will lead to recordings with progressively increasing numbers of neurons, while trial counts may only increase modestly. The analysis of such large-scale data increasingly relies on extracting collective neural population…
  preprints 2026 置信度 0.74
• Falsifiable substitution tests reveal task-structured neural evidence for auditory attention
  A neural decoder can predict a mental-state label without using information specific to that state. We made auditory-attention attribution falsifiable by requiring candidate evidence to persist in disjoint data, respond to capacity-matched substitutions of phy…
  preprints 2026 置信度 0.74
• On the Neurodynamics of Consciousness: A Field Theory for <em>Qualia</em> and Intentional Objects
  The Hard Problem of consciousness remains unsolved, as most current models lack explicit causal mechanisms. This paper proposes a novel theoretical framework in which consciousness is conceptualized as a nonlocal field influenced by brain energy dynamics. By i…
  preprints 2026 置信度 0.74
• Shared Neurobiological and Computational Mechanisms of Psychedelic, Contemplative, and Fasting-Induced Mystical Experience
  Psychedelics, contemplative practice, and fasting are physiologically unrelated interventions that nevertheless converge, across cultures and centuries, on a common experiential endpoint: the mystical state. Here I propose that this convergence reflects shared…
  preprints 2026 置信度 0.74
• Behavioral techniques and AR technology to systematically control the brain activity outside of the laboratory
  This study reviews the behavioral techniques that use the properties of visual stimuli to systematically control the activity of specific regions of an observer’s brain and proposes an Augmented Reality (AR) head-mounted display (HMD) that are implemented thes…
  preprints 2026 置信度 0.74
• Patterns of genAI bias in guiding prospective undergraduate students: a study of UK neuroscience programmes
  Generative artificial intelligence (genAI) tools are increasingly used by prospective higher education (HE) applicants seeking guidance on university and programme selection. Despite rapidly expanding use, little is known about how genAI systems may introduce …
  preprints 2026 置信度 0.74
• All Models are Wrong, Some are Annotated: Automating Metadata in Biomedical Repositories
  ABSTRACT Objective High-quality metadata is essential for scientific discovery, yet sparse annotations in rapidly growing repositories leave many biologically relevant details uncaptured. We evaluated whether large language models (LLMs) can accurately infer i…
  preprints 2026 置信度 0.74