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• Air quality and the risk of acute atrial fibrillation (EP-PARTICLES study): a nationwide study in Poland.
  Air pollution remains the single largest environmental health risk factor, while atrial fibrillation (AF) is the most prevalent arrhythmia globally. The study aimed to investigate the relationship between short-term exposure to air pollution and acute AF admis…
  pubmed Kurasz A, Lip GYH, Święczkowski M, Tomaszuk-Kazberuk A 等 2025 Dec 23 置信度 0.82
• Development of a framework for the hemodynamic impact of positive end-expiratory pressure in normal and heart failure conditions.
  Positive end-expiratory pressure (PEEP) improves respiratory conditions. However, the complex interaction between PEEP and hemodynamics in patients with heart failure makes it challenging to determine appropriate PEEP settings. In this study, we developed a fr…
  pubmed Nishikawa T, Uemura K, Matsushita H, Morita H 等 2025 Feb 1 置信度 0.82
• Future Directions for Quantitative Systems Pharmacology.
  In this chapter, we envision the future of Quantitative Systems Pharmacology (QSP) which integrates closely with emerging data and technologies including advanced analytics, novel experimental technologies, and diverse and larger datasets. Machine learning (ML…
  pubmed Schoeberl B, Musante CJ, Ramanujan S 2025 置信度 0.82
• Effect of Postoperative Neck-Shaft and Anteversion Angles on Biomechanical Outcomes in Proximal Femoral Osteotomy: An In Silico Study.
  Effective surgical planning is crucial for maximizing patient outcomes following complex orthopedic procedures such as proximal femoral osteotomy. In silico simulations can be used to assess how surgical variations in proximal femur geometry, such as femur nec…
  pubmed Bavil AY, Eghan-Acquah E, Diamond LE, Barrett R 等 2025 Apr 置信度 0.82
• Conditional Generative Models for Synthetic Tabular Data: Applications for Precision Medicine and Diverse Representations.
  Tabular medical datasets, like electronic health records (EHRs), biobanks, and structured clinical trial data, are rich sources of information with the potential to advance precision medicine and optimize patient care. However, real-world medical datasets have…
  pubmed Liu K, Altman RB 2025 Aug 置信度 0.82
• Optimal control of agent-based models via surrogate modeling.
  This paper describes and validates an algorithm to solve optimal control problems for agent-based models (ABMs). For a given ABM and a given optimal control problem, the algorithm derives a surrogate model, typically lower-dimensional, in the form of a system …
  pubmed Fonseca LL, Böttcher L, Mehrad B, Laubenbacher RC 2025 Jan 置信度 0.82
• Blockchain-enabled digital twin system for brain stroke prediction.
  A digital twin is a virtual model of a real-world system that updates in real-time. In healthcare, digital twins are gaining popularity for monitoring activities like diet, physical activity, and sleep. However, their application in predicting serious conditio…
  pubmed Upadrista V, Nazir S, Tianfield H 2025 Jan 14 置信度 0.82
• The impact of clinical phenotypes of coronary artery disease on outcomes in patients with atrial fibrillation: A post-hoc analysis of GLORIA-AF registry.
  Coronary artery disease (CAD) and atrial fibrillation (AF) often coexist, but the impact of clinical phenotypes of CAD on outcomes in AF patients in the non-vitamin K antagonist oral anticoagulant drugs (NOACs) era is less well understood.
  pubmed Huang B, Liu Y, Lam HM, Ishiguchi H 等 2025 Mar 置信度 0.82
• An Attention-Based Multidimensional Fault Information Sharing Framework for Bearing Fault Diagnosis.
  Deep learning has performed well in feature extraction and pattern recognition and has been widely studied in the field of fault diagnosis. However, in practical engineering applications, the lack of sample size limits the potential of deep learning in fault d…
  pubmed Hu Y, Xie Q, Yang X, Yang H 等 2025 Jan 3 置信度 0.82
• Study on Few-Shot Fault Diagnosis Method for Marine Fuel Systems Based on DT-SViT-KNN.
  The fuel system serves as the core component of marine diesel engines, and timely and effective fault diagnosis is the prerequisite for the safe navigation of ships. To address the challenge of current data-driven fault-diagnosis-based methods, which have diff…
  pubmed Li S, Qi L, Shi J, Xiao H 等 2024 Dec 24 置信度 0.82
• Patient-specific spine digital twins: a computational characterization of the idiopathic scoliosis.
  Scoliosis is an idiopathic three-dimensional spine strain. The orthopedic parameter used to diagnose and evaluate the severity of the strain is Cobb's angle. This study proposes using this clinical parameter to reproduce a digital twin of the spine, calculate …
  pubmed Landinez D, Rodríguez CF, Cifuentes De la Portilla C 2025 Jan 10 置信度 0.82
• Digital twins for the plant sciences.
  pubmed Ganapathysubramanian B, Sarkar S, Singh A, Singh AK 2025 May 置信度 0.82
• Retroperitoneal Müllerian cyst causing uterine protrusion in a teenage girl.
  To describe a rare case of a retroperitoneal Müllerian cyst in a teenage girl with a protruding uterus and associated urogenital anomalies, and to discuss the challenges faced in differential diagnosis and management of such cases.
  pubmed Chu FC, Wang HH, Chen YT, Chuang YC 等 2025 Jan 置信度 0.82
• A Fuel Cell Power Supply System Equipped with Artificial Gill Membranes for Underwater Applications.
  This work proposes a fuel cell power supply system for underwater applications (e.g., autonomous underwater vehicles), where artificial gills, based on a polymer membrane, harvest the required oxygen from the ambient water. In this system, a circulating a…
  pubmed Merckelbach L, Georgopanos P 2025 Mar 置信度 0.82
• An ODE-based swift and dynamic sewer airflow model.
  Airflow models are powerful tools for ventilation design to achieve odour and corrosion mitigation in sewer networks. Currently, there lacks a model able to efficiently predict in-sewer dynamic airflows, as all available dynamic models with an acceptable accur…
  pubmed Shi T, Li J, Ge J, Watts S 等 2025 Apr 1 置信度 0.82
• DigiLoCS: A leap forward in predictive organ-on-chip simulations.
  Digital twins, driven by data and mathematical modelling, have emerged as powerful tools for simulating complex biological systems. In this work, we focus on modelling the clearance on a liver-on-chip as a digital twin that closely mimics the clearance functio…
  pubmed Aravindakshan MR, Mandal C, Pothen A, Schaller S 等 2025 置信度 0.82
• Predecting power transformer health index and life expectation based on digital twins and multitask LSTM-GRU model.
  Power transformers play a crucial role in enabling the integration of renewable energy sources and improving the overall efficiency and reliability of smart grid systems. They facilitate the conversion, transmission, and distribution of power from various sour…
  pubmed El-Rashidy N, Sultan YA, Ali ZH 2025 Jan 8 置信度 0.82
• A cognitive digital twin approach to improving driver compliance and accident prevention.
  Advanced Driver Assistance Systems (ADAS) are crucial for enhancing driving safety by alerting drivers to unrecognized risks. However, traditional ADAS often fail to account for individual decision-making processes, including drivers' perceptions of the enviro…
  pubmed Gu Y, Li S, Qi J, Fu B 等 2025 Mar 置信度 0.82
• Digital Twins for Clinical and Operational Decision-Making: Scoping Review.
  The health care industry must align with new digital technologies to respond to existing and new challenges. Digital twins (DTs) are an emerging technology for digital transformation and applied intelligence that is rapidly attracting attention. DTs are virtua…
  pubmed Riahi V, Diouf I, Khanna S, Boyle J 等 2025 Jan 8 置信度 0.82
• A comprehensive review of digital twin in healthcare in the scope of simulative health-monitoring.
  Objective: Digital twins (DTs) emerged in the wake of Industry 4.0 and the creation of cyber-physical systems, motivated by the increased availability and variability of machine and sensor data. DTs are a concept to create a digital representation of a physica…
  pubmed Nadeem M, Kostic S, Dornhöfer M, Weber C 等 2025 Jan-Dec 置信度 0.82 Scope (computer science)Health careDigital healthImplementationComputer science
• Digital-twin driven alignment control method for marine shafting with air spring vibration isolation system.
  Shafting alignment is crucial for marine propulsion systems and may affect the safety and stability of ship operations. Air spring vibration isolation systems (ASVISs) for marine shafting can help control the shafting alignment state by actively adjusting air …
  pubmed Liu S, Shi L, Xu W, Hu Z 2025 Jan 7 置信度 0.82
• Research on detection and treatment of loose zones in weak fracture zone tunnel.
  Determining the extent of tunnel loosening zones is a crucial factor in establishing reasonable support parameters. Addressing the challenge of testing tunnel loosening zones, this study focused on the Dongmachang Tunnel No. 1. Seismic wave methods are employe…
  pubmed Zheng X, Huang F, Wang S, Zeng Z 等 2025 Jan 7 置信度 0.82
• Research on Parameter Compensation Method and Control Strategy of Mobile Robot Dynamics Model Based on Digital Twin.
  Inspection robots, which improve hazard identification and enhance safety management, play a vital role in the examination of high-risk environments in many fields, such as power distribution, petrochemical, and new energy battery factories. Currently, the pos…
  pubmed Li R, Shang X, Wang Y, Liu C 等 2024 置信度 0.82
• Digital Twin-Assisted Lightpath Provisioning and Nonlinear Mitigation in C+L+S Multiband Optical Networks.
  Multiband (MB) optical transmission targets increasing the capacity of operators' optical transport networks. However, nonlinear impairments (NLI) affect each optical channel in the C+L+S bands differently, and, therefore, the routing and spectrum assignment (…
  pubmed Ghasrizadeh S, Khare P, Costa N, Ruiz M 等 2024 Dec 17 置信度 0.82
• Effects of Cyclic Aeration Subsurface Drip Irrigation on Greenhouse Tomato Quality and Water and Fertilizer Use Efficiency.
  Tomato (Jinglu 6335) was selected for assessing the impact of varying fertilizer (F:N-P 2 O 5 -K 2 O) and aeration rates on crop quality, as well as water and fertilizer utilization efficiency during the cyclic aeration subsurface drip irrigation process. Four…
  pubmed Liu Z, Long K, Zeng J, Zhang Y 等 2024 Dec 20 置信度 0.82
• Hollow Fiber Microreactor Combined with Digital Twin to Optimize the Antimicrobial Evaluation Process.
  In order to reproduce pharmacokinetics (PK) profiles seen in vivo, the Hollow Fiber Infection Model (HFIM) is a useful in vitro module in the evaluation of antimicrobial resistance. In order to reduce the consumption of culture medium and drugs, we developed a…
  pubmed Noda K, Kasama T, Shinohara M, Hamada M 等 2024 Dec 20 置信度 0.82
• A Thermal Cycler Based on Magnetic Induction Heating and Anti-Freezing Water Cooling for Rapid PCR.
  Distinguished by its exceptional sensitivity and specificity, Polymerase Chain Reaction (PCR) is a pivotal technology for pathogen detection. However, traditional PCR instruments that employ thermoelectric cooling (TEC) are often constrained by cost, efficienc…
  pubmed Xie Y, Jiang Q, Chang C, Zhao X 等 2024 Nov 30 置信度 0.82
• Characterization of the Optical Properties of Photoluminescent Turbid Media Using an Integrating Sphere and Monte Carlo Simulations.
  In this paper, we report on the measurement of the optical properties (absorption and scattering coefficients) of photoluminescent turbid media using a homemade integrating sphere setup equipped with a tunable monochromatic light source. The hemispherical refl…
  pubmed Jelken J, Brall T, Gelbing P, Foschum F 等 2024 Dec 12 置信度 0.82
• Digital Twins Use in Plastic Surgery: A Systematic Review.
  Background/Objectives: Digital twin technology, initially developed for engineering and manufacturing, has entered healthcare. In plastic surgery, digital twins (DTs) have the potential to enhance surgical precision, personalise treatment plans, and improve pa…
  pubmed Seth I, Lim B, Lu PYJ, Xie Y 等 2024 置信度 0.82 MedicinePlastic surgeryScopusData extractionMEDLINE
• Reliable and streamlined model setup for digital twin assessment of fracture healing.
  In large animal models of bone fracture repair, postmortem torsional testing is commonly used to assess healing biomechanics. Bending and axial tests are physiologically relevant, but much less commonly performed. Virtual torsional testing using image-based fi…
  pubmed Bahrami M, Frew K, Hughes J, Dailey HL 2025 Feb 置信度 0.82
• Transforming precision medicine: The potential of the clinical artificial intelligent single-cell framework.
  The editorial, "Clinical and translational mode of single-cell measurements: An artificial intelligent single-cell," introduces the innovative clinical artificial intelligence single-cell (caiSC) system, which merges AI with single-cell informatics to advance …
  pubmed Baumgartner C, Brislinger D 2025 Jan 置信度 0.82
• Exploration of an adaptive proton therapy strategy using CBCT with the concept of digital twins.
  Objective. This study aims to develop a digital twin (DT) framework to achieve adaptive proton prostate stereotactic body radiation therapy (SBRT) with fast treatment plan selection and patient-specific clinical target volume (CTV) setup uncertainty. Prostate …
  pubmed Chang CW, Tian Z, Qiu RLJ, Scott Mcginnis H 等 2025 Jan 17 置信度 0.82
• Expanding first-line options for depression: Protocol of a pragmatic comparative effectiveness trial of yoga vs. behavioral activation (the COMPARE study).
  Depression is a prevalent mental health condition in the United States and a significant cause of morbidity and mortality. The treatment guidelines for depression recommends either psychotherapy, such as behavioral activation (BA), or a second-generation antid…
  pubmed Sylvia LG, Busch AM, Rabideau DJ, Gold A 等 2025 置信度 0.82
• How does Prognostics and Health Management (PHM) develop in the engineering domain: A bibliometric analysis with critical review.
  In recent years, Prognostics and Health Management (PHM) have been considered in broad industrial areas to improve the effectiveness of maintenance activities. In chemical engineering domains, PHM is regarded to have big potential for reliability and safety ma…
  pubmed Shi H, Geng J, Demichela M 2024 Dec 30 置信度 0.82
• Personalized Heart Digital Twins Detect Substrate Abnormalities in Scar-Dependent Ventricular Tachycardia.
  Current outcomes from catheter ablation for scar-dependent ventricular tachycardia (VT) are limited by high recurrence rates and long procedure durations. Personalized heart digital twin technology presents a noninvasive method of predicting critical substrate…
  pubmed Waight MC, Prakosa A, Li AC, Bunce N 等 2025 Feb 25 置信度 0.82
• Impact of thrombus composition on virtual thrombectomy procedures using human clot analogues mechanical data.
  Endovascular thrombectomy (EVT) aims at restoring blood flow in case of acute ischemic stroke by removing the thrombus occluding a large cerebral artery. During the procedure with stent-retriever, the thrombus is captured within the device, which is then retri…
  pubmed Fregona V, Luraghi G, Fereidoonnezhad B, Gijsen FJH 等 2025 Mar 置信度 0.82
• The present and future of digital health, digital medicine, and digital therapeutics for allergic diseases.
  Digital health, digital medicine, and digital therapeutics integrate advanced computer technologies into healthcare, aiming to improve efficiency and patient outcomes. These technologies offer innovative solutions for the management of allergic diseases, which…
  pubmed Zhang H, Cao Y, Jiang H, Zhou Q 等 2025 Jan 置信度 0.82
• Modeling, evaluation and metrics performance of the SyncLMKD in distributed kinematics variations.
  Modeling the Digital Twin (DT) is an important resource for accurately representing the physical entity, enabling it to deliver functional services, meet application requirements, and address the disturbances between the physical and digital realms. This artic…
  pubmed Cardoso FS, de Souza Araújo T, Rohrich RF, de Oliveira AS 2025 Jan 3 置信度 0.82
• Construction and transcriptomic analysis of salinity-induced lipid-rich flocculent microalgae.
  The lack of cost-effective nutrient sources and harvesting methods is currently a major obstacle to the production of sustainable biofuels from microalgae. In this study, Chlorella pyrenoidosa was cultured with saline wastewater in a stirred photobioreactor, a…
  pubmed Huang KX, Vadiveloo A, Zhou JL, Zhong H 等 2025 Jan 置信度 0.82
• Influence of next-generation artificial intelligence on headache research, diagnosis and treatment: the junior editorial board members' vision - part 2.
  Part 2 explores the transformative potential of artificial intelligence (AI) in addressing the complexities of headache disorders through innovative approaches, including digital twin models, wearable healthcare technologies and biosensors, and AI-driven drug …
  pubmed Petrušić I, Chiang CC, Garcia-Azorin D, Ha WS 等 2025 Jan 2 置信度 0.82
• A novel method for intelligent operation and maintenance of transformers using deep visual large model DETR + X and digital twin.
  To achieve real-time monitoring and intelligent maintenance of transformers, a framework based on deep vision and digital twin has been developed. An enhanced visual detection model, DETR + X, is proposed, implementing multidimensional sample dat…
  pubmed Zhang X, Sun W, Chen K, Song S 2025 Jan 2 置信度 0.82
• High-fidelity computational fluid dynamics modeling to simulate perfusion through a bone-mimicking scaffold.
  Breast cancer cells sense shear stresses in response to interstitial fluid flow in bone and induce specific biological responses. Computational fluid dynamics models have been instrumental in estimating these shear stresses to relate the cell mechanoresponse t…
  pubmed Venkatesh S, Teeraratkul C, Rovito N, Mukherjee D 等 2025 Mar 置信度 0.82
• Flexible inference for animal learning rules using neural networks.
  Understanding how animals learn is a central challenge in neuroscience, with growing relevance to the development of animal- or human-aligned artificial intelligence. However, existing approaches tend to assume fixed parametric forms for the learning rule (e.g…
  pubmed Liu YH, Geadah V, Pillow J 2025 置信度 0.82
• A simulation based digital twin approach to assessing the organization of response to emergency calls.
  In emergency situations, timely contact with emergency medical communication centers (EMCCs) is critical for patient outcomes. Increasing call volumes and economic constraints are challenging many countries, necessitating organizational changes in EMCCs. This …
  pubmed Penverne Y, Martinez C, Cellier N, Pehlivan C 等 2024 Dec 31 置信度 0.82
• A novel quantitative diagnosis method for rolling bearing faults based on digital twin model.
  Dual-impulse behaviors of rolling bearings have been widely researched for quantitative diagnosis. However, it is challenging to accurately extract entry and exit moments of the fault from noise-contaminated raw signals. To address this issue, a novel quantita…
  pubmed Cui L, Li W, Wang X, Liu D 2025 Feb 置信度 0.82
• The role of industry 4.0 enabling technologies for predicting, and managing of algal blooms: Bridging gaps and unlocking potential.
  Recent advancements in data analytics, predictive modeling, and optimization have highlighted the potential of integrating algal blooms (ABs) with Industry 4.0 technologies. Among these innovations, digital twins (DT) have gained prominence, driven by the rapi…
  pubmed Sheik AG, Sireesha M, Kumar A, Dasari PR 等 2025 Mar 置信度 0.82
• 2D echocardiography video to 3D heart shape reconstruction for clinical application.
  Transthoracic Echocardiography (TTE) is a crucial tool for assessing cardiac morphology and function quickly and non-invasively without ionising radiation. However, the examination is subject to intra- and inter-user variability and recordings are often limite…
  pubmed Laumer F, Rubi L, Matter MA, Buoso S 等 2025 Apr 置信度 0.82
• A new approach for bin packing problem using knowledge reuse and improved heuristic.
  The two-dimensional (2D) irregular packing problem is a combinatorial optimization problem with NP-complete characteristics, which is common in the production process of clothing, ships, and plate metals. The classic packing solution is a hybrid algorithm base…
  pubmed Fang J, Chen X, Rao Y, Peng Y 等 2024 Dec 30 置信度 0.82
• An efficient method for identifying surface damage in hydraulic concrete buildings.
  Traditional hydraulic structures rely on manual visual inspection for apparent integrity, which is not only time-consuming and labour-intensive but also inefficient. The efficacy of deep learning models is frequently constrained by the size of available data, …
  pubmed Yang L, Zhu D, Liu X 2024 Dec 28 置信度 0.82
• Concept and framework of digital twin human geographical environment.
  The human geographical environment is a comprehensive setting formed by the interaction between human activities and the geographical environment, characterized by its complexity and vulnerability. Applying the digital twin method to create a new research mode…
  pubmed Xu B, Xiao X, Wang Y, Kang Y 等 2025 Jan 置信度 0.82
• Elevator fault diagnosis based on digital twin and PINNs-e-RGCN.
  The rapid development of urbanization has led to a continuous rise in number of elevators. This has led to elevator failures from time to time. At present, although there are some studies on elevator fault diagnosis, they are more or less limited by the lack o…
  pubmed Wang Q, Chen L, Xiao G, Wang P 等 2024 Dec 28 置信度 0.82
• A faulty simulation model guided Ramanujan Digital twin architecture for rotating machine health monitoring.
  The conventional widely-used health monitoring methods for rotating machines have shortcomings such as the reliance on the selection of the preset parameters. Also, the strong noise interference caused by factors such as transmission path hinders the practical…
  pubmed Hu W, Wang T, Chu F 2025 Feb 置信度 0.82
• Fast and accurate prediction of drug induced proarrhythmic risk with sex specific cardiac emulators.
  In silico trials for drug safety assessment require many high-fidelity 3D cardiac simulations to predict drug-induced QT interval prolongation, which is often computationally prohibitive. To streamline this process, we developed sex-specific emulators for a fa…
  pubmed Dominguez-Gomez P, Zingaro A, Baldo-Canut L, Balzotti C 等 2024 Dec 26 置信度 0.82
• Efficacy of virtual reality pure-tone audiometry in training of hearing test for audiologist.
  The immersive virtual reality (VR) simulator is advantageous because it is cost-effective, realistic, can be controlled directly by the user, and can be integrated into education and training in otorhinolaryngology. The present study explored the feasibility o…
  pubmed Kwak C, Kim J, Jang H, Han W 等 2024 Dec 30 置信度 0.82
• Building a modular and multi-cellular virtual twin of the synovial joint in Rheumatoid Arthritis.
  Rheumatoid arthritis is a complex disease marked by joint pain, stiffness, swelling, and chronic synovitis, arising from the dysregulated interaction between synoviocytes and immune cells. Its unclear etiology makes finding a cure challenging. The concept of d…
  pubmed Zerrouk N, Augé F, Niarakis A 2024 Dec 24 置信度 0.82
• From tradition to smart: A comprehensive review of the evolution and prospects of land use planning tools.
  Land use planning tools are essential for effective land management. However, existing research has not thoroughly explored the evolution and future potential of these tools. This study addresses this gap through comprehensive literature review and data collec…
  pubmed Liu Y, Timo de Vries W, Zhang G, Cui X 2024 Dec 15 置信度 0.82
• In silico metabolic modelling links microbiome-derived metabolites to risk factors of Alzheimer's disease.
  The gut microbiome has become increasingly recognized for its role in the pathogenesis of Alzheimer's disease (AD) and is thought to influence AD pathogenesis via metabolic crosstalk with the host. However, mechanistic pathways connecting the gut microbiome to…
  pubmed Hensen T, Ahmad S, Kastenmüller G, Kraaij R 等 2025 置信度 0.82
• Building a Human Digital Twin (HDTwin) Using Large Language Models for Cognitive Diagnosis: Algorithm Development and Validation.
  Human digital twins have the potential to change the practice of personalizing cognitive health diagnosis because these systems can integrate multiple sources of health information and influence into a unified model. Cognitive health is multifaceted, yet resea…
  pubmed Sprint G, Schmitter-Edgecombe M, Cook D 2024 Dec 23 置信度 0.82
• Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53.
  Neuroblastoma is the most common extra-cranial solid tumour in children. Over half of all high-risk cases are expected to succumb to the disease even after chemotherapy, surgery, and immunotherapy. Although the importance of MYCN amplification in this disease …
  pubmed Wertheim KY, Chisholm R, Richmond P, Walker D 2024 Dec 置信度 0.82
• scRGCL: a cell type annotation method for single-cell RNA-seq data using residual graph convolutional neural network with contrastive learning.
  Cell type annotation is a critical step in analyzing single-cell RNA sequencing (scRNA-seq) data. A large number of deep learning (DL)-based methods have been proposed to annotate cell types of scRNA-seq data and have achieved impressive results. However, ther…
  pubmed Yuan L, Sun S, Jiang Y, Zhang Q 等 2024 Nov 22 置信度 0.82
• Computer-generated Clinical Decision-making in the Treatment of Pulmonary Atresia with Intact Ventricular Septum.
  Pulmonary atresia with intact ventricular septum is a multifactorial disease requiring complex surgeries. The treatment route is determined based on the right ventricle (RV) size, tricuspid annulus size and coronary circulation dependency of RV. Since multiple…
  pubmed Yıldırım C, Ural B, Odemis E, Donmazov S 等 2025 Apr 置信度 0.82
• Quantitative Systems Pharmacology Modeling in Immuno-Oncology: Hypothesis Testing, Dose Optimization, and Efficacy Prediction.
  Despite an increasing number of clinical trials, cancer is one of the leading causes of death worldwide in the past decade. Among all complex diseases, clinical trials in oncology have among the lowest success rates, in part due to the high intra- and inter-tu…
  pubmed Wang H, Arulraj T, Ippolito A, Popel AS 2025 置信度 0.82
• Relative contributions of genetic and environmental factors to palatal morphology: a longitudinal twin study.
  This study aimed to determine the genetic and environmental contributions to phenotypic variations of palatal morphology during development.
  pubmed Giri J, Bockmann M, Brook A, Gurr A 等 2024 Dec 4 置信度 0.82
• Bridging silicon and carbon worlds with digital twins and on-chip systems in drug discovery.
  This perspective discusses the convergence of digital twin (DT) technology and on-the-chip systems as pivotal innovations in precision medicine, substantially advancing drug discovery. DT leverages extensive health data to create dynamic virtual patient models…
  pubmed Akbarialiabad H, Seyyedi MS, Paydar S, Habibzadeh A 等 2024 Dec 19 置信度 0.82
• European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics - Update 2024.
  This guideline was developed in close collaboration with multidisciplinary experts from the European Association of Dermato-Oncology (EADO), the European Dermatology Forum (EDF) and the European Organization for Research and Treatment of Cancer (EORTC). Recomm…
  pubmed Garbe C, Amaral T, Peris K, Hauschild A 等 2025 Jan 17 置信度 0.82
• Enhancing unity-based AR with optimal lossless compression for digital twin assets.
  The rapid development of Digital Twin (DT) technology has underlined challenges in resource-constrained mobile devices, especially in the application of extended realities (XR), which includes Augmented Reality (AR) and Virtual Reality (VR). These challenges l…
  pubmed Hlayel M, Mahdin H, Hayajneh M, AlDaajeh SH 等 2024 置信度 0.82
• Triboelectric Mat Multimodal Sensing System (TMMSS) Enhanced by Infrared Image Perception for Sleep and Emotion-Relevant Activity Monitoring.
  To implement digital-twin smart home applications, the mat sensing system based on triboelectric sensors is commonly used for gait information collection from daily activities. Yet traditional mat sensing systems often miss upper body motions and fail to adequ…
  pubmed Xu J, Guo X, Zhang Z, Liu H 等 2025 Feb 置信度 0.82
• Leveraging artificial intelligence and machine learning to accelerate discovery of disease-modifying therapies in type 1 diabetes.
  Progress in developing therapies for the maintenance of endogenous insulin secretion in, or the prevention of, type 1 diabetes has been hindered by limited animal models, the length and cost of clinical trials, difficulties in identifying individuals who will …
  pubmed Shapiro MR, Tallon EM, Brown ME, Posgai AL 等 2025 Mar 置信度 0.82
• Digital twins for chronic lung diseases.
  Digital twins have recently emerged in healthcare. They combine advances in cyber-physical systems, modelling and computation techniques, and enable a bidirectional flow of information between the physical and virtual entities. In respiratory medicine, progres…
  pubmed Gonsard A, Genet M, Drummond D, Apolline Gonsard 等 2024 Oct 置信度 0.82 MedicineDigital healthHealth careIntensive care medicineData science
• Deciphering circulating tumor cells binding in a microfluidic system thanks to a parameterized mathematical model.
  The spread of metastases is a crucial process in which some questions remain unanswered. In this work, we focus on tumor cells circulating in the bloodstream, the so-called Circulating Tumor Cells (CTCs). Our aim is to characterize their trajectories under the…
  pubmed Ciavolella G, Granet J, Goetz JG, Osmani N 等 2025 Mar 7 置信度 0.82
• Molecular Interactions and Responsive Locations of CO(2)-Responsive Surfactants in an Oil-Water-Surfactant System: Molecular Dynamics Simulation and Free Energy Perturbation.
  Understanding the mechanism of a CO 2 -responsive surfactant is essential for enhancing its industrial applications. Conventional experimental methods face challenges in pinpointing the exact location of proton transfer within the system and in accurately desc…
  pubmed Lei X, Liu B, Chen Z 2024 Dec 31 置信度 0.82
• Simulated effects of surgical corrections on bone-implant micromotion and implant stresses in paediatric proximal femoral osteotomy.
  Proximal femoral osteotomy (PFO) is a surgical intervention, typically performed on paediatric population, that aims to correct femoral deformities caused by different pathologies (e.g., slipped capital femoral epiphysis). A PFO involves introduction of an imp…
  pubmed Bavil AY, Eghan-Acquah E, Dastgerdi AK, Diamond LE 等 2025 Feb 置信度 0.82
• From bits to bedside: entering the age of digital twins in cardiac electrophysiology.
  This State of the Future Review describes and discusses the potential transformative power of digital twins in cardiac electrophysiology. In this 'big picture' approach, we explore the evolution of mechanistic modelling based digital twins, their current and i…
  pubmed Bhagirath P, Strocchi M, Bishop MJ, Boyle PM 等 2024 Dec 3 置信度 0.82 Cardiac electrophysiologyTransformative learningElectrophysiologyComputer scienceData science
• Virtual imaging trials in medicine: A brief takeaway of the lessons from the first international summit.
  The rapid advancement of medical technologies presents significant challenges for researchers and practitioners. While traditional clinical trials remain the gold standard, they are often limited by high costs, lengthy durations, and ethical constraints. In co…
  pubmed Samei E, Abadi E, Bakic P, Bliznakova K 等 2025 Mar 置信度 0.82
• Closed-Loop Automated Control System of Extracorporeal Membrane Oxygenation and Left Ventricular Assist Device Support in Cardiogenic Shock.
  Venoarterial extracorporeal membrane oxygenation (VA-ECMO) benefits patients with cardiogenic shock (CS) but can increase left ventricular afterload and exacerbate pulmonary edema. Adding a percutaneous left ventricular assist device (LVAD) to VA-ECMO can opti…
  pubmed Unoki T, Uemura K, Yokota S, Matsushita H 等 2025 Jun 1 置信度 0.82
• FPGA-Based Sensors for Distributed Digital Manufacturing Systems: A State-of-the-Art Review.
  The combination of distributed digital factories (D 2 Fs) with sustainable practices has been proposed as a revolutionary technique in modern manufacturing. This review paper explores the convergence of D 2 F with innovative sensor technology, concentrating on…
  pubmed Khan L, Isanaka SP, Liou F 2024 Dec 2 置信度 0.82
• Digital Twin for a Frequency Mixer Used as a Phase Sensor.
  The Portuguese Institute for Quality is responsible for the realization and dissemination of the frequency standard in Portugal. There are several techniques for frequency transfer, but we use a frequency mixer to detect phase variations between two light sign…
  pubmed Pires C, Abreu M, Godinho I, Agostinho R 等 2024 Nov 27 置信度 0.82
• IoT-Cloud, VPN, and Digital Twin-Based Remote Monitoring and Control of a Multifunctional Robotic Cell in the Context of AI, Industry, and Education 4.0 and 5.0.
  The monitoring and control of an assembly/disassembly/replacement (A/D/R) multifunctional robotic cell (MRC) with the ABB 120 Industrial Robotic Manipulator (IRM), based on IoT (Internet of Things)-cloud, VPN (Virtual Private Network), and digital twin (DT) te…
  pubmed Filipescu A, Simion G, Ionescu D, Filipescu A 2024 Nov 22 置信度 0.82
• A computational workflow for end-to-end simulation of percutaneous absorption.
  Presented is the development of a workflow for end-to-end (e2e) in silico modelling of percutaneous absorption under a range of test conditions, integrating multiple calculation and analysis steps for in-silico simulation of dermal absorption. The aim is to ac…
  pubmed Zhang D, Deacon BN, Li W, Lian G 等 2025 Feb 10 置信度 0.82
• Kinetic cooling in mid-infrared methane photoacoustic spectroscopy: A quantitative analysis via digital twin verification.
  This study presents a detailed quantitative analysis of kinetic cooling in methane photoacoustic spectroscopy, leveraging the capabilities of a digital twin model. Using a quantum cascade laser tuned to 1210.01 cm⁻¹, we investigated the effe…
  pubmed Rück T, Pangerl J, Escher L, Jobst S 等 2024 Dec 置信度 0.82
• Age assessment of Chinese Tibetan twins using multiple skeletal age estimation methods: A case report.
  This case presents a unique age estimation involving Chinese Tibetan twins, where one of them has been arrested for alleged rape. His parents claimed he was about 13 years old without providing any official age documentation. Since age is important in cri…
  pubmed Luo S, Fan F, Liu M, Qiu LR 等 2025 Feb 置信度 0.82
• A Matlab Toolbox for cardiac electrophysiology simulations on patient-specific geometries.
  In this paper, we present CardioMat, a Matlab toolbox for cardiac electrophysiology simulation based on patient-specific anatomies. The strength of CardioMat is the easy and fast construction of electrophysiology cardiac digital twins from segmented anatomical…
  pubmed Biasi N, Seghetti P, Parollo M, Zucchelli G 等 2025 Feb 置信度 0.82
• "Population" in biology and statistics.
  The development of a biological notion of "population" over the first century of the theory of evolution has been commented upon by a number of historians and philosophers of biology. Somewhat less commonly discussed, however, is the parallel development of th…
  pubmed Bertoldi N, Pence CH 2025 Feb 置信度 0.82
• Objectively Measured Physical Activity Using Wrist-Worn Accelerometers as a Predictor of Incident Alzheimer's Disease in the UK Biobank.
  Alzheimer's disease (AD) affects over 6 million people and is the seventh-leading cause of death in the United States. This study compares wrist-worn accelerometry-derived PA measures against traditional risk factors for incident AD in the UK Biobank.
  pubmed Zhao A, Cui E, Leroux A, Zhou X 等 2025 Jan 16 置信度 0.82
• Artificial Intelligence in Medical Metaverse: Applications, Challenges, and Future Prospects.
  The medical metaverse is a combination of medicine, computer science, information technology and other cutting-edge technologies. It redefines the method of information interaction about doctor-patient communication, medical education and research through the …
  pubmed Yang JM, Chen BJ, Li RY, Huang BQ 等 2024 Dec 置信度 0.82
• Filtering-free complex-valued DSB-16QAM generation for a 100 G direct detection optical interconnection.
  In this Letter, a complex-valued double-sideband 16QAM (CV-DSB-16QAM) signaling scheme is proposed and experimentally demonstrated in a 100-Gb/s intensity modulation/direct detection (IM/DD) interconnection system. Unlike the conventional real-valued double-si…
  pubmed Ming J, Song J, Wen Y, He H 等 2024 Dec 15 置信度 0.82
• All Together Now: Data Work to Advance Privacy, Science, and Health in the Age of Synthetic Data.
  There is a disconnect between data practices in biomedicine and public understanding of those data practices, and this disconnect is expanding rapidly every day (with the emergence of synthetic data and digital twins and more widely adopted Artificial Intellig…
  pubmed Fernández-Rhodes L, Wagner JK 2025 置信度 0.82
• A multimodal model in the prediction of the delivery mode using data from a digital twin-empowered labor monitoring system.
  This study aims to address the limitations of current clinical methods in predicting delivery mode by constructing a multimodal neural network-based model. The model utilizes data from a digital twin-empowered labor monitoring system, including computerized ca…
  pubmed Bai J, Kang X, Wang W, Yang Z 等 2024 Jan-Dec 置信度 0.82
• Healthcare providers' experiences of maternity care service delivery during the COVID-19 pandemic in the United Kingdom: a follow-up systematic review and qualitative evidence synthesis.
  During the COVID-19 pandemic, there was substantial reconfiguration of maternity care services, affecting both users and healthcare providers (HCPs), in the United Kingdom (UK) and globally.
  pubmed Dasgupta T, Bousfield E, Pathak Y, Horgan G 等 2024 置信度 0.82
• Does sibling family structure matter in the emotion understanding development in preschoolers?
  The objective of the study was to investigate the impact of sibling family structure -including the number of children, age gaps, presence of a twin, sibling position, and gender composition - on emotion understanding and its development in children aged 5-6&#…
  pubmed Aslanova M, Gavrilova M, Iurina E 2024 置信度 0.82
• Residual risk prediction in anticoagulated patients with atrial fibrillation using machine learning: A report from the GLORIA-AF registry phase II/III.
  Although oral anticoagulation decreases the risk of thromboembolism in patients with atrial fibrillation (AF), a residual risk of thrombotic events still exists. This study aimed to construct machine learning (ML) models to predict the residual risk in these p…
  pubmed Liu Y, Chen Y, Olier I, Ortega-Martorell S 等 2025 Mar 置信度 0.82
• A scalable framework for learning the geometry-dependent solution operators of partial differential equations.
  Solving partial differential equations (PDEs) using numerical methods is a ubiquitous task in engineering and medicine. However, the computational costs can be prohibitively high when many-query evaluations of PDE solutions on multiple geometries are needed. H…
  pubmed Yin M, Charon N, Brody R, Lu L 等 2024 Dec 置信度 0.82
• Advancing personalised care in atrial fibrillation and stroke: The potential impact of AI from prevention to rehabilitation.
  Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant fina…
  pubmed Ortega-Martorell S, Olier I, Ohlsson M, Lip GYH 等 2025 May 置信度 0.82
• Beyond the sarcoma center: establishing the Sarcoma HASM network-a Hub and Spoke Model network for global integrated and precision care.
  The landscape of sarcoma treatment has evolved significantly, transitioning from amputations to limb-sparing surgeries, underpinned by advancements in multidisciplinary strategies. The establishment of specialized sarcoma centers has been pivotal, though chall…
  pubmed Fuchs B, Gronchi A 2024 Dec 置信度 0.82
• Metaverse forensics framework: A NIST based investigation framework for metaverse.
  The Metaverse is an intersection of virtual, augmented, and mixed reality that offers users an interactive virtual environment. This new technology has enormous possibilities for both people and companies. However, owing to the existence of inherent vulnerabil…
  pubmed Shandilya SK, Singh Y, Izonin I, Hentosh L 2024 Nov 置信度 0.82
• Personalized nutrition in type 2 diabetes remission: application of digital twin technology for predictive glycemic control.
  Background: Type 2 Diabetes (T2D) is a complex condition marked by insulin resistance and beta-cell dysfunction. Traditional dietary interventions, such as low-calorie or low-carbohydrate diets, typically overlook individual variability in postprandial glycemi…
  pubmed Shamanna P, Joshi S, Thajudeen M, Shah L 等 2024 置信度 0.82 GlycemicType 2 diabetesMedicineDiabetes mellitusModel predictive control
• Probing the limits and capabilities of diffusion models for the anatomic editing of digital twins.
  Numerical simulations of cardiovascular device deployment within digital twins of patient-specific anatomy can expedite and de-risk the device design process. Nonetheless, the exclusive use of patient-specific data constrains the anatomic variability that can …
  pubmed Kadry K, Gupta S, Nezami FR, Edelman ER 2024 Dec 5 置信度 0.82
• Quantitative Systems Pharmacology-Based Digital Twins Approach Supplements Clinical Trial Data for Enzyme Replacement Therapies in Pompe Disease.
  Pompe disease is a rare, progressive neuromuscular disease caused by deficient lysosomal glycogen degradation, and includes both late-onset (LOPD) and severe infantile-onset (IOPD) phenotypes. Due to very small patient numbers in IOPD and the high phenotypic h…
  pubmed Kaddi C, Tao M, Bergeler S, George K 等 2025 Feb 置信度 0.82
• A Comprehensive Exploration of Digital Twinning in Spine Surgery.
  One recent innovation in the health care landscape is the integration of Digital Twin (DT) in the field of spine surgery. DT, first used in 2002 is defined as the replication of physical entities in a virtual environment. It has emerged as a transformative too…
  pubmed Lomax N, Vinjamuri S, Vinjamuri S, Franco D 等 2025 Jun 1 置信度 0.82
• A multiscale model of immune surveillance in micrometastases gives insights on cancer patient digital twins.
  Metastasis is the leading cause of death in patients with cancer, driving considerable scientific and clinical interest in immunosurveillance of micrometastases. We investigated this process by creating a multiscale mathematical model to study the interactions…
  pubmed L Rocha H, Aguilar B, Getz M, Shmulevich I 等 2024 Dec 4 置信度 0.82