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• Advanced Predictive Analytics for Fetal Heart Rate Variability Using Digital Twin Integration.
  Fetal heart rate variability (FHRV) is a critical indicator of fetal well-being and autonomic nervous system development during labor. Traditional monitoring methods often provide limited insights, potentially leading to delayed interventions and suboptimal ou…
  pubmed Lwin TC, Zin TT, Tin P, Kino E 等 2025 Feb 27 置信度 0.82
• Sensing Techniques for Structural Health Monitoring: A State-of-the-Art Review on Performance Criteria and New-Generation Technologies.
  This systematic review examines the capabilities, challenges, and practical implementations of the most widely utilized and emerging sensing technologies in structural health monitoring (SHM) for infrastructures, addressing a critical research gap. While many …
  pubmed Mardanshahi A, Sreekumar A, Yang X, Barman SK 等 2025 Feb 26 置信度 0.82
• Integration of Real Signals Acquired Through External Sensors into RoboDK Simulation of Robotic Industrial Applications.
  Ensuring synchronization between real-world sensor data and industrial robotic simulations remains a critical challenge in digital twin and virtual commissioning applications. This study proposes an innovative method for integrating real sensor signals into Ro…
  pubmed Cristoiu C, Ivan AM 2025 Feb 25 置信度 0.82
• A Review of Environmental Control Strategies and Models for Modern Agricultural Greenhouses.
  As crucial sites for optimizing crop growth conditions, greenhouses have gained increasing favor among scholars due to their potential to significantly enhance food production. Greenhouse control involves regulating environmental parameters such as temperature…
  pubmed Chen S, Liu A, Tang F, Hou P 等 2025 Feb 25 置信度 0.82
• Credibility Assessment for Digital Twins in Vehicle-in-the-Loop Test Based on Information Entropy.
  Digital twins in vehicle-in-the-loop (VIL) test has great practical significance for the functional development, testing and evaluation of intelligent vehicle. The study about the credibility assessment of dynamically evolving models still lacks effective appr…
  pubmed Gao T, Chen L, Zhang X, Guo J 等 2025 Feb 24 置信度 0.82
• Validating the Virtual Calendering Process With 3D-Reconstructed Composite Electrode: An Optimization Framework for Electrode Design.
  Calendering is an essential fabrication step for lithium-ion battery electrodes, aimed at achieving the target density through mechanical compression. During this process, the electrode's microstructure significantly deforms, affecting its electrochemical perf…
  pubmed Lim J, Song J, Kim KG, Koo JK 等 2025 Jul 置信度 0.82
• Model-based aberration corrected microscopy inside a glass tube.
  Microscope objectives achieve near diffraction-limited performance only when used under the conditions they are designed for. In nonstandard geometries, such as thick cover slips or curved surfaces, severe aberrations arise, inevitably impairing high-resolutio…
  pubmed Cox DWS, Knop T, Vellekoop IM 2025 Jun 置信度 0.82
• Digital PCR Assay Utilizing In-Droplet Methylation-Sensitive Digestion for Estimation of Fetal cfDNA From Plasma.
  Recent guidelines suggest that non-invasive prenatal screening (NIPS) should be offered to all patients with singleton and twin pregnancies. Accurate determination of fetal fraction in cell-free DNA (cfDNA) is vital for reliable NIPS outcomes. We propose a met…
  pubmed Dannebaum R, Mikhaylichenko O, Siegel D, Li C 等 2025 Apr 置信度 0.82
• VM-UNet++ research on crack image segmentation based on improved VM-UNet.
  Cracks are common defects in physical structures, and if not detected and addressed in a timely manner, they can pose a severe threat to the overall safety of the structure. In recent years, with advancements in deep learning, particularly the widespread use o…
  pubmed Tang W, Wu Z, Wang W, Pan Y 等 2025 Mar 15 置信度 0.82
• Integrating artificial intelligence in drug discovery and early drug development: a transformative approach.
  Artificial intelligence (AI) can transform drug discovery and early drug development by addressing inefficiencies in traditional methods, which often face high costs, long timelines, and low success rates. In this review we provide an overview of how to integr…
  pubmed Ocana A, Pandiella A, Privat C, Bravo I 等 2025 Mar 14 置信度 0.82 Computer scienceDrug developmentDrug discoveryData scienceIdentification (biology)
• Research on the disaster mechanism and control technology of large section high waste dump slope in open pit mines.
  An important part of open-pit mining is the waste dump, where the topsoil and rocks extracted during open-pit excavation are discharged, mainly including the upper waste material and the base that carries the waste material below. Most of the external dumping …
  pubmed Mu H 2025 Mar 14 置信度 0.82
• Editorial: Digital twins in medicine-transition from theoretical concept to tool used in everyday care.
  pubmed Gilbert S, Drummond D, Cotte F, Ziemssen T 2025 置信度 0.82
• Control of medical digital twins with artificial neural networks.
  The objective of precision medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be personalized and dynamically u…
  pubmed Böttcher L, Fonseca LL, Laubenbacher RC 2025 Mar 13 置信度 0.82
• Challenges and opportunities in uncertainty quantification for healthcare and biological systems.
  Uncertainty quantification (UQ) is an essential aspect of computational modelling and statistical prediction. Multiple applications, including geophysics, climate science and aerospace engineering, incorporate UQ in the development and translation of new techn…
  pubmed Kimpton LM, Paun LM, Colebank MJ, Volodina V 2025 Mar 13 置信度 0.82
• Quantification of total uncertainty in the physics-informed reconstruction of CVSim-6 physiology.
  When predicting physical phenomena through simulation, quantification of the total uncertainty due to multiple sources is as crucial as making sure the underlying numerical model is accurate. Possible sources include irreducible aleatoric uncertainty due to no…
  pubmed De Florio M, Zou Z, Schiavazzi DE, Karniadakis GE 2025 Mar 13 置信度 0.82
• A comparison of Gaussian processes and polynomial chaos emulators in the context of haemodynamic pulse-wave propagation modelling.
  Computational modelling of the cardiovascular system is a promising future direction for patient-specific healthcare. However, the computational cost of these simulators is a bottleneck for their practical use in clinic for real-time digital twins . Emulation …
  pubmed Paun LM, Colebank MJ, Husmeier D 2025 Mar 13 置信度 0.82
• Investigation on Improving the Hot Corrosion Resistance of Selective Laser Melting Manufactured Inconel 625 by Pre-Oxidation Heat Treatment.
  The present study was focused on assessing the molten salt-induced hot corrosion resistance of selective laser melting (SLM) manufactured Inconel 625 at 900 °C for 96 h and investigating the possibility of improving the superalloy's corrosion resistance b…
  pubmed Badea TA, Condruz MR 2025 Feb 28 置信度 0.82
• Current Methods and Technologies for Storage Tank Condition Assessment: A Comprehensive Review.
  This study investigates the current industry practices for storage tank assessment and the possibilities for improving inspection methods using the latest technologies on the market. This article presents the main methods and technologies for non-destructive t…
  pubmed Stoicescu AA, Ripeanu RG, Tănase M, Toader L 2025 Feb 27 置信度 0.82
• PLA Reinforced with Limestone Waste: A Way to Sustainable Polymer Composites.
  Waste stone sludge generated by the extractive industry has traditionally posed significant disposal challenges. This study redefines stone sludge as a valuable raw material by incorporating it into polylactic acid (PLA) to create sustainable composite materia…
  pubmed Sousa D, Baleia C, Amaral P 2025 Feb 28 置信度 0.82
• Adaptive digital twin integration with multilevel inverter control for energy efficient smart rehabilitation systems.
  This research proposes an innovative framework integrating adaptive Digital Twin (DT) models with Multi-Level Inverter (MLI) control to improve energy efficiency in advanced rehabilitation systems. By utilizing real-time monitoring and adaptive adjustment of p…
  pubmed Rashid SM, Ghiasi AR 2025 Mar 12 置信度 0.82
• Atrial fibrillation burden in clinical practice, research, and technology development: a clinical consensus statement of the European Society of Cardiology Council on Stroke and the European Heart Rhythm Association.
  Atrial fibrillation (AF) is one of the most common cardiac diseases and a complicating comorbidity for multiple associated diseases. Many clinical decisions regarding AF are currently based on the binary recognition of AF being present or absent with the categ…
  pubmed Doehner W, Boriani G, Potpara T, Blomstrom-Lundqvist C 等 2025 Mar 5 置信度 0.82
• From traditional robotic deployments towards assisted robotic deployments in nuclear decommissioning.
  The history around teleoperation and deployment of robotic systems in constrained and dangerous environments such as nuclear is a long and successful one. From the 1940s, robotic manipulators have been used to manipulate dangerous substances and enable work in…
  pubmed Lopez Pulgarin EJ, Hopper D, Montgomerie J, Kell J 等 2025 置信度 0.82
• Portable and Self-Powered Sensing AI-Enabled Mask for Emotional Recognition in Virtual Reality.
  With the increasing development of metaverse and human-computer interaction (HMI) technologies, artificial intelligence (AI) applications in virtual reality (VR) environments are receiving significant attention. This study presents a self-sensing facial recogn…
  pubmed He D, Chen H, Zhao X, Fan C 等 2025 Mar 26 置信度 0.82
• How a vast digital twin of the Yangtze River could prevent flooding in China.
  pubmed Wang X, Wu B, Zhou G, Wang T 等 2025 Mar 置信度 0.82
• Quantifying, predicting, and mitigating nitrous oxide emissions in a full-scale partial nitritation/anammox reactor treating reject water.
  In this paper, a set of mathematical tools are developed and assembled to quantify, predict and virtually assess N 2 O emission mitigation strategies in partial nitritation (PN) / anammox (ANX) granular based reactors. The proposed approach is constructed upon…
  pubmed Flores-Alsina X, Vangsgaard AK, Uri-Carreño N, Nielsen PH 等 2025 Jun 15 置信度 0.82
• Sensing the Future of Thrombosis Management: Integrating Vessel-on-a-Chip Models, Advanced Biosensors, and AI-Driven Digital Twins.
  Thrombotic events, such as strokes and deep vein thrombosis, remain a significant global health burden, with traditional diagnostic methods often failing to capture the complex, patient-specific nuances of thrombosis risk. This Perspective explores the revolut…
  pubmed Zhao YC, Wang Z, Zhao H, Yap NA 等 2025 Mar 28 置信度 0.82
• 3D anatomical digital twins: New generation virtual models to navigate robotic partial nephrectomy.
  Objective 3D virtual models have gained interest in urology, particularly in the context of robotic partial nephrectomy. From these, newly developed "anatomical digital twin models" reproduce both the morphological and anatomical characteristics of the organs,…
  pubmed Amparore D, Piana A, Piramide F, De Cillis S 等 2025 置信度 0.82
• In silico oncology: a mechanistic multiscale model of clinical prostate cancer response to external radiation therapy as the core of a digital (virtual) twin. Sensitivity analysis and a clinical adaptation approach.
  Prostate cancer (PCa) is the most frequent diagnosed malignancy in male patients in Europe and radiation therapy (RT) is a main treatment option. However, current RT concepts for PCa have an imminent need to be rectified in order to modify the radiotherapeutic…
  pubmed Stamatakos G, Kolokotroni E, Panagiotidou F, Tsampa S 等 2025 置信度 0.82
• Artificial intelligence and gender equity: An integrated approach for health professional education.
  As artificial intelligence (AI) increasingly integrates into health workplaces, evidence suggests AI can exacerbate gender inequity. Health professional programmes have a role to play in ensuring graduates grasp the challenges facing working in an AI-mediated …
  pubmed Bearman M, Ajjawi R 2025 Oct 置信度 0.82
• Anatomy education potential of the first digital twin of a Korean cadaver.
  The objective of this study is to explore innovative integration within the field of anatomy education by leveraging HoloLens 2 Augmented Reality Head-Mounted Display (AR HMD) technology and real-time cloud rendering. Initial 3D datasets, comprising extensive …
  pubmed Choi SY, Choi DH, Cho SH, Ahn SH 等 2025 置信度 0.82
• Validating the predictions of mathematical models describing tumor growth and treatment response.
  Despite advances in methods to interrogate tumor biology, the observational and population-based approach of classical cancer research and clinical oncology does not enable anticipation of tumor outcomes to hasten the discovery of cancer mechanisms and persona…
  pubmed Lorenzo G, Hormuth DA 2nd, Wu C, Pash G 等 2025 Feb 26 置信度 0.82
• Coprime dual-velocity encoding for extended velocity dynamic range in 4D flow magnetic resonance imaging.
  In the field of cardiovascular imaging, four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) provides non-invasive assessment of blood flow. Dual velocity encoding (dual-VENC) strategies have emerged to obtain quantitative information on both low…
  pubmed Bartoli MB, Boccalini S, Chechin D, Boussel L 等 2025 Summer 置信度 0.82
• Quantifying anatomically-based in-silico electrocardiogram variability for cardiac digital twins.
  Human cardiac Cardiac digital twins (CDTs) are digital replicas of patient hearts, designed to match clinical observations precisely. The electro-cardiogram (ECG), as the most common non-invasive electrophysiology (EP) measurement, has been recently successful…
  pubmed Zappon E, Gsell MAF, Gillette K, Plank G 2025 May 置信度 0.82
• Closed-Loop Navigation of a Kinetic Zone Diagram for Redox-Mediated Electrocatalysis Using Bayesian Optimization, a Digital Twin, and Automated Electrochemistry.
  Molecular electrocatalysis campaigns often require tuning multiple experimental parameters to obtain kinetically insightful electrochemical measurements, a prohibitively time-consuming task when performing comprehensive studies across multiple catalysts and su…
  pubmed Pence MA, Hazen G, Rodríguez-López J 2025 Apr 1 置信度 0.82
• A multi objective optimization framework for smart parking using digital twin pareto front MDP and PSO for smart cities.
  Smart cities are designed to improve the quality of life by efficiently using resources and smart parking is an important part of this puzzle to help alleviate traffic congestion and efficiently address energy consumption and search time for parking spaces. Ho…
  pubmed Sahu D, Sinha P, Prakash S, Yang T 等 2025 Mar 5 置信度 0.82
• All-day cloud property and occurrence probability dataset based on satellite remote sensing data.
  The cloud property database and different type cloud occurrence probability datasets are helpful for meteorological research and application, as well as climate comprehension. Building on the foundation of CldNet with all-day cloud type recognition capability,…
  pubmed Nie L, Chen Y, Zhang D 2025 Mar 5 置信度 0.82
• Predicting Membrane Fouling of Submerged Membrane Bioreactor Wastewater Treatment Plants Using Machine Learning.
  Membrane fouling remains a significant challenge in the operation of membrane bioreactors (MBRs). Plant operators rely heavily on observations of filtration performance from noisy sensor data to assess membrane fouling conditions and lab-based protocols for pl…
  pubmed Zhu Y, Wang Y, Zhu E, Ma Z 等 2025 May 27 置信度 0.82
• A digital-twin platform for cryospheric disaster warning.
  With increasing glacial hazards due to global climate warming, a promising digital-twin-based platform has been proposed for early warning of cryospheric disasters.
  pubmed Cui Y, Li Y, Tang H, Turowski JM 等 2024 Oct 置信度 0.82
• Hemodynamics comparison of an hour-long rest and activity state data in a human coronary digital twin.
  Although it is well established that hemodynamics can significantly influence the location and progression of cardiovascular disease (CVD), and 3D blood flow metrics are recognized as potential diagnostic indicators of these diseases, the dynamics of these met…
  pubmed Mavi JK, Tanade C, Ladd W, Geddes J 等 2024 Jul 置信度 0.82
• Digital twins for trans people in healthcare: queer, phenomenological and bioethical considerations.
  Healthcare is one of the domains in which artificial intelligence (AI) is already having a major impact. Of interest is the idea of the digital twin (DT), an AI-powered technology that generates a real-time representation of the patient's body, offering the po…
  pubmed Guerrero Quiñones JL, Puzio A 2025 Nov 21 置信度 0.82
• Risk of major cardiovascular events and all-cause death in patients with bronchiectasis and associated resistance to antimicrobial drugs.
  To assess the impact of antimicrobial resistance (AMR) on major adverse cardiovascular event (MACE) risk in patients with bronchiectasis.
  pubmed Bucci T, Guo R, Yiu KH, Lip GYH 等 2025 Oct 28 置信度 0.82
• Evidence for intermittent coupling of intramyocardial small, engineered heart tissues acutely implanted into rabbit myocardium.
  Electrical integration of human-induced pluripotent stem-cell-derived cardiomyocyte (hiPSC-CM)-based tissue with the host myocardium is a requirement of successful regeneration therapy. This study was designed to identify electrical coupling in the acute phase…
  pubmed Huethorst E, Bishop MJ, Burton FL, Denning C 等 2025 Sep 29 置信度 0.82
• Digital twin-enhanced three-organ microphysiological system for studying drug pharmacokinetics in pregnant women.
  Pregnant women represent a vulnerable group in pharmaceutical research due to limited knowledge about drug metabolism and safety of commonly used corticosteroids like prednisone due to ethical and practical constraints. Current preclinical models, including an…
  pubmed Graf K, Murrieta-Coxca JM, Vogt T, Besser S 等 2025 置信度 0.82
• From FAIR to CURE: Guidelines for Computational Models of Biological Systems.
  Guidelines for managing scientific data have been established under the FAIR principles requiring that data be Findable, Accessible, Interoperable, and Reusable. In many scientific disciplines, especially computational biology, both data and models are key to …
  pubmed Sauro HM, Agmon E, Blinov ML, Gennari JH 等 2025 Feb 21 置信度 0.82
• Research on status monitoring and positioning compensation system for digital twin of parallel robots.
  Industrial parallel robots are characterized by their stable structure and grasping pick-up speed, and they are commonly used in food packaging and parts assembly industries. However, the traditional robot teaching pendants often provide monitoring data under …
  pubmed Zhang Y, Gao P, Wang Z, He Q 2025 置信度 0.82
• Deconstructing Barisanus' medieval casting technology based on digital twins.
  The Italian 12th-century copper alloy doors of Barisanus have long been the subject of art historical studies and have recently been fully documented photogrammetrically and archaeometrically. In addition, digital twins of the three Barisanus doors in Ravello,…
  pubmed Asmus B, Fera M, Mödlinger M 2025 Mar 3 置信度 0.82
• Embracing the future of medicine with virtual patients.
  The adoption of virtual patients promises to revolutionize pharmaceutical R&D and health care through more patient-centric approaches and is driven by integrating innovations in computational approaches, AI, and advanced in vitro human model systems. Virtu…
  pubmed Wang K, Parrott NJ, Lavé T 2025 Mar 置信度 0.82
• Imitation Learning for Path Planning in Cardiac Percutaneous Interventions.
  Mitral regurgitation is a valvular heart disease particularly affecting the aging population. Minimally invasive transcatheter procedures offer benefits over traditional open-chest surgery but require significant operator skill and hand-eye coordination, makin…
  pubmed Peloso A, Damiano R, Zhang X, Bicchi A 等 2025 Aug 置信度 0.82
• Anthropomorphic Torso Phantoms and Validation of Their Physical and Digital Twins for Body-Area Radio-Communication Applications.
  Artificial phantoms play an important role in the development of body-area radio-communication devices and networks. This work aims to design, fabricate and validate physical anthropomorphic phantoms (PAP) of torso with their complementary digital twin models …
  pubmed Joseph L, Zradzinski P, Chezhian AS, Mandal B 等 2025 Jun 置信度 0.82
• DECIDE-Twin: A Framework for AI-Enabled Digital Twins in Clinical Decision-Making.
  AI-enabled digital twins (DTs) are advanced virtual models of a complex real-world system, which have the potential to transform clinical decision-making. Despite the growing interest in such DTs, the literature lacks a unified framework for their development …
  pubmed Rahimi SA, Baradaran A, Khameneifar F, Gore G 等 2025 Sep 置信度 0.82
• Quantitative metrics for evaluating surgical dexterity using virtual reality simulations.
  This study develops and evaluates quantitative metrics to assess surgical dexterity within virtual reality (VR) simulations to enhance surgical training and performance. By employing advanced VR technology, this research systematically investigates the influen…
  pubmed Wu M, Kit CY, Su ELM, Yeong CF 等 2025 置信度 0.82
• Multi-scale machine learning model predicts muscle and functional disease progression in FSHD.
  Facioscapulohumeral muscular dystrophy (FSHD) is a genetic neuromuscular disorder characterized by progressive muscle degeneration with substantial variability in severity and progression patterns. FSHD is a highly heterogeneous disease; however, current clini…
  pubmed Blemker SS, Riem L, DuCharme O, Pinette M 等 2025 Feb 20 置信度 0.82
• Developing Campus Digital Twin Using Interactive Visual Analytics Approach.
  Digital Twins (DTs) are increasingly recognized for their potential to improve efficiency and decision-making in various domains of the built environment. Despite their promise, challenges like cost, complexity, interoperability, and data integration remain. T…
  pubmed Ye X, Jamonnak S, Van Zandt S, Newman G 等 2024 Dec 置信度 0.82
• Digital-Twin-Assisted Insights Into Irreversible Capacity and Activation Strategy Power High-Loading Solid-State Batteries.
  In solid-state lithium-ion batteries, the fraction of active materials involved in electrode electrochemistry reduces with the increase of electrode thickness. Conventional wisdom suggests that the degree of reaction linearly decreases toward the current colle…
  pubmed Sun Y, Ning Y, Qiang Z, Xiang L 等 2025 Sep 1 置信度 0.82
• Hemodynamics indicates differences between patients with and without a stroke outcome after left ventricular assist device implantation.
  Stroke remains a leading cause of complications and mortality in heart failure patients treated with a Left Ventricular Assist Device (LVAD). Hemodynamics plays a central role underlying post-LVAD stroke risk and etiology. Yet, detailed quantitative assessment…
  pubmed Sahni A, Majee S, Pal JD, McIntyre EE 等 2025 May 置信度 0.82
• Direct oral anticoagulants versus no anticoagulation for the prevention of stroke in survivors of intracerebral haemorrhage with atrial fibrillation (PRESTIGE-AF): a multicentre, open-label, randomised, phase 3 trial.
  Direct oral anticoagulants (DOACs) reduce the rate of thromboembolism in patients with atrial fibrillation but the benefits and risks in survivors of intracerebral haemorrhage are uncertain. We aimed to determine whether DOACs reduce the risk of ischaemic stro…
  pubmed Veltkamp R, Korompoki E, Harvey KH, Harvey ER 等 2025 Mar 15 置信度 0.82
• Optimized real-time homodyne detection of bright pico-second twin beams by digital signal processing.
  Twin beams are useful tools in quantum technologies. However, due to their asymmetry in photon number distribution, a scheme needs to be optimized in order to fully exploit their quantum advantage. Here, we demonstrate a detection scheme for bright pico-second…
  pubmed Yan H, Zhao W, Guo X, Li X 2025 Mar 1 置信度 0.82
• Factors associated with decreased anal sphincter tone and the accuracy of forced anal examinations to detect individuals having receptive anal intercourse: an observational study.
  Forced anal examinations are used to prosecute sexual and gender minorities (SGM) in multiple countries under the presumption that decreased sphincter tone, assessed by a finger inserted into the anal canal, can detect persons practising receptive anal interco…
  pubmed Nyitray AG, Rosser BRS, Hazra A, Nitkowski J 等 2024 Jun 置信度 0.82
• The intrinsic spatiotemporal structure of cognitive functions inspires the intervention of brain functions.
  pubmed Wang Y, Zhang C, Liu Q, Jing X 2025 置信度 0.82
• Digital twin-driven operational CycleGAN-based multiple virtual-physical mappings for remaining useful life prediction under limited life cycle data.
  Accurately predicting the remaining useful life (RUL) of complex equipment plays a vital role in maintaining modern manufacturing systems' operational safety and reliability. This challenge has attracted considerable interest within the domain of intelligent o…
  pubmed Xu Q, Lei Z, Gu S, Wen G 等 2025 置信度 0.82
• Acquisition and Modeling of Material Appearance Using a Portable, Low Cost, Device.
  Material appearance acquisition allows researchers to capture the optical properties of surfaces and use them in different tasks such as material analysis, digital twins reproduction, 3D configurators, augmented and virtual reality, etc. Precise acquisition of…
  pubmed Marelli D, Bianco S, Ciocca G 2025 Feb 13 置信度 0.82
• Research on the Phenomenological Constitutive Relationship Model of Silicone Structural Adhesives for Glass Curtain Walls.
  Silicone structural adhesives (SSAs) play a critical role in load transfer within glass curtain wall systems. With the increasing service life of existing glass curtain walls in recent years, their structural safety has become a significant concern across vari…
  pubmed Jin N, Zhao J, Liang Y, Zhao X 2025 Feb 19 置信度 0.82
• Fluctuating Genetic Influences at Three Different Stages of Development of Dental Arches: A Complex System.
  Background/Objectives : The development of dental arches is a complex adaptive system with interactions between genetic and environmental factors. At different developmental stages, the relative contribution of these factors varies. The aims of this project we…
  pubmed Hughes T, Mahmood Z, Giri J, Townsend G 等 2025 Feb 3 置信度 0.82
• A mathematical model for the investigation of combined treatment of radiopharmaceutical therapy and PARP inhibitors.
  Although the combined treatment with radiopharmaceutical therapy (RPT) and poly (ADP-ribose) polymerase inhibitors (PARPi) shows promise, a critical challenge remains in the limited quantitative understanding needed to optimize treatment protocols. This study …
  pubmed Ryhiner M, Song Y, Hong J, Ferreira CVG 等 2025 Jul 置信度 0.82
• Differences of tsRNA expression profiles efficiently discriminate monozygotic twins in peripheral blood.
  Monozygotic twins (MZTs) share nearly identical genomic DNA sequences, making traditional forensic short tandem repeats (STR) genotyping methods ineffective for distinguishing between them. In recent years, the use of epigenetic factors in forensic application…
  pubmed Tian M, Liu X, Wang D, Wang Y 等 2025 Apr 置信度 0.82
• Digital twins in dermatology: a new era of personalized skin care.
  The concept of digital twins, initially developed in engineering and manufacturing, is now creating a significant impact in healthcare, particularly in dermatology. A digital twin is a virtual representation of an individual's skin, designed by integrating rea…
  pubmed Haykal D, Diala Haykal 2025 置信度 0.82 DermatologySkin careMedicineNursing
• Generative spatial artificial intelligence for sustainable smart cities: A pioneering large flow model for urban digital twin.
  Rapid urbanization, alongside escalating resource depletion and ecological degradation, underscores the critical need for innovative urban development solutions. In response, sustainable smart cities are increasingly turning to cutting-edge technologies-such a…
  pubmed Huang J, Bibri SE, Keel P 2025 Mar 置信度 0.82
• Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine.
  Medical digital twins (MDTs) are virtual representations of patients that simulate the biological, physiological, and clinical processes of individuals to enable personalized medicine. With the increasing complexity of omics data, particularly multiomics, ther…
  pubmed Alsaedi S, Gao X, Gojobori T 2025 Aug 置信度 0.82
• Machine learning-enabled multiscale modeling platform for damage sensing digital twin in piezoelectric composite structures.
  Nondestructive evaluation (NDE) of aerospace structures plays a crucial role in their successful operation under harsh environments. Most NDE methods, however, lack real-time in-situ predictive capabilities of evolving damage and are conducted in a post-mortem…
  pubmed Ghosh S, Dan S, Tarafder P 2025 Feb 24 置信度 0.82
• Natural language processing of electronic medical records identifies cardioprotective agents for anthracycline induced cardiotoxicity.
  In this retrospective observational study, we aimed to investigate the potential of natural language processing (NLP) for drug repositioning by analyzing the preventive effects of cardioprotective drugs against anthracycline-induced cardiotoxicity (AIC) using …
  pubmed Kawazoe Y, Tsuchiya M, Shimamoto K, Seki T 等 2025 Feb 24 置信度 0.82
• Digital Twins: The Future for Ventricular Tachycardia Ablation?
  pubmed Qin D, Singh JP 2025 Feb 25 置信度 0.82
• The MicroMap is a network visualisation resource for microbiome metabolism.
  The human microbiome plays a crucial role in metabolism and thereby influences health and disease. Constraint-based reconstruction and analysis (COBRA) has proven an attractive framework to generate mechanism-derived hypotheses along the nutrition-host-microbi…
  pubmed Thinnes CC, Waschkowitz R, Courtney E, Culligan E 等 2025 Feb 16 置信度 0.82
• Digital twin systems for musculoskeletal applications: A current concepts review.
  Digital twin (DT) systems, which involve creating virtual replicas of physical objects or systems, have the potential to transform healthcare by offering personalised and predictive models that grant deeper insight into a patient's condition. This review explo…
  pubmed Diniz P, Grimm B, Garcia F, Fayad J 等 2025 May 置信度 0.82
• Uncertainty in cardiovascular digital twins despite non-normal errors in 4D flow MRI: Identifying reliable biomarkers such as ventricular relaxation rate.
  Cardiovascular digital twins and mechanistic models can be used to obtain new biomarkers from patient-specific hemodynamic data. However, such model-derived biomarkers are only clinically relevant if the uncertainty of the biomarkers is smaller than the variat…
  pubmed Tunedal K, Ebbers T, Cedersund G 2025 Apr 置信度 0.82
• Benefits of Early Catheter Ablation in Patients With Atrial Fibrillation: A Nationwide Cohort Study.
  Although early rhythm control showed better clinical outcomes in patients with atrial fibrillation (AF), limited data exist on the relationship between the timing of atrial fibrillation catheter ablation (AFCA) and clinical outcomes.
  pubmed Kwon S, Lee SR, Choi EK, Kim B 等 2025 May 置信度 0.82
• The Neutrophil-to-Lymphocyte Ratio Is an Independent Inflammatory Biomarker for Adverse Events in Patients With Atrial Fibrillation: Insights From the Murcia AF Project II (MAFP-II) Cohort Study.
  Systemic inflammation plays a central role in atrial fibrillation (AF). The neutrophil-to-lymphocyte ratio (NLR) is a simple hematological index that has been shown to be associated with prognosis in different pathologies.
  pubmed Soler-Espejo E, Marín F, López-Gálvez R, Ramos-Bratos MP 等 2025 Feb 置信度 0.82
• Externally validated and clinically useful machine learning algorithms to support patient-related decision-making in oncology: a scoping review.
  This scoping review systematically maps externally validated machine learning (ML)-based models in cancer patient care, quantifying their performance, and clinical utility, and examining relationships between models, cancer types, and clinical decisions. By sy…
  pubmed Santos CS, Amorim-Lopes M 2025 Feb 21 置信度 0.82
• Foundations of a knee joint digital twin from qMRI biomarkers for osteoarthritis and knee replacement.
  This study forms the basis of a digital twin system of the knee joint, using advanced quantitative MRI (qMRI) and machine learning to advance precision health in osteoarthritis (OA) management and knee replacement (KR) prediction. We combined deep learning-bas…
  pubmed Hoyer G, Gao KT, Gassert FG, Luitjens J 等 2025 Feb 21 置信度 0.82
• A digital twin based forecasting framework for power flow management in DC microgrids.
  The ability to forecast system conditions is integral to the definition and functionality of digital twins. While forecasting methods have been explored for use in digital twin systems, the integration of feedback mechanisms for real-time forecasting and in-si…
  pubmed Sado K, Peskar J, Downey A, Khan J 等 2025 Feb 21 置信度 0.82
• Telemedicine-based integrated management of atrial fibrillation in village clinics: a cluster randomized trial.
  In rural China, where healthcare relies on village doctors (nonspecialized practitioners who work exclusively in their village clinics), delivering integrated atrial fibrillation (AF) management poses challenges. We developed a telemedicine-based, village doct…
  pubmed Chu M, Zhang S, Gong J, Yang S 等 2025 Apr 置信度 0.82
• Assessing the performance of zero-shot visual question answering in multimodal large language models for 12-lead ECG image interpretation.
  Large Language Models (LLM) are increasingly multimodal, and Zero-Shot Visual Question Answering (VQA) shows promise for image interpretation. If zero-shot VQA can be applied to a 12-lead electrocardiogram (ECG), a prevalent diagnostic tool in the medical fiel…
  pubmed Seki T, Kawazoe Y, Ito H, Akagi Y 等 2025 置信度 0.82
• An efficient end-to-end computational framework for the generation of ECG calibrated volumetric models of human atrial electrophysiology.
  Computational models of atrial electrophysiology (EP) are increasingly utilized for applications such as the development of advanced mapping systems, personalized clinical therapy planning, and the generation of virtual cohorts and digital twins. These models …
  pubmed Zappon E, Azzolin L, Gsell MAF, Thaler F 等 2025 Feb 5 置信度 0.82
• Reevaluating the Role of Education in Cognitive Decline and Brain Aging: Insights from Large-Scale Longitudinal Cohorts across 33 Countries.
  Why education is linked to higher cognitive function in aging is fiercely debated. Leading theories propose that education reduces brain decline in aging, enhances tolerance to brain pathology, or that it does not affect cognitive decline but rather reflects h…
  pubmed Fjell AM, Røgeberg O, Sørensen Ø, Amlien IK 等 2025 Jan 29 置信度 0.82
• Advancing Health Care With Digital Twins: Meta-Review of Applications and Implementation Challenges.
  Digital twins (DTs) are digital representations of real-world systems, enabling advanced simulations, predictive modeling, and real-time optimization in various fields, including health care. Despite growing interest, the integration of DTs in health care face…
  pubmed Ringeval M, Etindele Sosso FA, Cousineau M, Paré G 2025 Feb 19 置信度 0.82
• Machine Learning Approaches to Prognostication in Traumatic Brain Injury.
  This review investigates the use of machine learning (ML) in prognosticating outcomes for traumatic brain injury (TBI). It underscores the benefits of ML models in processing and integrating complex, multimodal data-including clinical, imaging, and physiologic…
  pubmed Badjatia N, Podell J, Felix RB, Chen LK 等 2025 Feb 19 置信度 0.82
• Three-dimensional analysis of mandibular and condylar growth using artificial intelligence tools: a comparison of twin-block and Frankel II Appliances.
  Analyzing the morphological growth changes upon mandibular advancement between Twin Block (TB) and Functional Regulator II (FR2) in Class II patients involves measuring the condylar and mandibular changes in terms of linear and volumetric measurements, as well…
  pubmed Shihabi R, Liu Y, Kusaibati AM, Maraabeh F 等 2025 Feb 18 置信度 0.82
• Identification of digital twins to guide interpretable AI for diagnosis and prognosis in heart failure.
  Heart failure (HF) is a highly heterogeneous condition, and current methods struggle to synthesize extensive clinical data for personalized care. Using data from 343 HF patients, we developed mechanistic computational models of the cardiovascular system to cre…
  pubmed Gu F, Meyer AJ, Ježek F, Zhang S 等 2025 Feb 18 置信度 0.82
• Real-time update algorithms for digital twin models of distribution network equipment under internet of things and optical imaging technology.
  In order to achieve more efficient, accurate and intelligent substation equipment management and overall work efficiency of the substation, improve the work quality of the substation, innovate the data transmission mode and basic algorithm of the distribution …
  pubmed Shen J, Hu L, Yang Y, Li Y 等 2025 Feb 18 置信度 0.82
• Utilization of precision medicine digital twins for drug discovery in Alzheimer's disease.
  Alzheimer's disease (AD) presents significant challenges in drug discovery and development due to its complex and poorly understood pathology and etiology. Digital twins (DTs) are recently developed virtual real-time representations of physical entities that e…
  pubmed Ren Y, Pieper AA, Cheng F, Yunxiao Ren 等 2025 Apr 置信度 0.82 NeurologyDiseaseMedicineDrug discoveryDrug
• Apixaban in patients with nonvalvular atrial fibrillation, heart failure and low body weight: A report from a global federated research dataset.
  Atrial fibrillation (AF) and low body weight (BW, <60 kg) are common in patients with heart failure (HF). However, the safety and effectiveness of direct oral anticoagulants (DOACs) in this group remain unclear. This study compares the efficacy and s…
  pubmed Monzo L, Baudry G, Hernandez G, Denquin O 等 2025 May 置信度 0.82
• Building a physics-based virtual refrigerated container filled with fruit in ventilated packaging.
  We build a validated physics-based model of a refrigerated container filled with fruit in ventilated packaging. This model of a virtual container is the basis for simulations in an accompanying paper on citrus fruit shipped overseas from South Africa to Europe…
  pubmed Defraeye T, Verreydt C, Gonthier J, Lukasse L 等 2024 Dec 置信度 0.82
• Micromechanical finite element modeling of crystalline lipid-based materials: monoglyceride-based oleogels and their composites.
  The mechanical properties of crystalline lipid-based materials are dependent on the microscale structure formed during the crystallization process. In this work, we show for the first time that the mechanical properties of such materials can be mathematically …
  pubmed Grahn P, Lassila P, Valoppi F 2025 May 19 置信度 0.82
• Sex Differences in Post-Noncardiac Surgery Risks Assessed Using the Revised Cardiac Risk Index　- A Nationwide Retrospective Cohort Study.
  The Revised Cardiac Risk Index (RCRI) has been incorporated into preoperative assessment guidelines and is used for simple preoperative screening; however, validation studies within large populations are limited. Moreover, although sex differences in periopera…
  pubmed Seki T, Kawazoe Y, Takiguchi T, Akagi Y 等 2025 Aug 25 置信度 0.82
• Enabling the twin transition of the textile industry: A systematic literature review.
  The textile industry, a significant resource consumer and polluter, ranks as the fourth-largest sector in raw material consumption and the fifth-largest emitter of greenhouse gases. To address these significant environmental challenges, there is an urgent need…
  pubmed Hassan R, Acerbi F, Terzi S, Rosa P 2025 Mar 置信度 0.82
• Predicting major adverse cardiac events in diabetes and chronic kidney disease: a machine learning study from the Silesia Diabetes-Heart Project.
  People living with diabetes mellitus (DM) and chronic kidney disease (CKD) are at significantly high risk of cardiovascular events (CVEs), however the predictive performance of traditional risk prediction methods are limited.
  pubmed Kwiendacz H, Huang B, Chen Y, Janota O 等 2025 Feb 15 置信度 0.82
• Biomimetic Digital Twins and Multiomics: Applications to Rheumatoid Arthritis and the Potential Reclassification of Variants of Unknown Clinical Significance.
  The National Academies of Sciences, Engineering, and Medicine issued a report on December 15, 2023, "Foundational Research Gaps and Future Directions for Digital Twins." This described the importance of using biomimetic digital twins and multiomics in research…
  pubmed Kearns WG, Glick J, Baisch L, Benner A 等 2025 Apr 置信度 0.82
• Enhancing wind power forecasting accuracy through LSTM with adaptive wind speed calibration (C-LSTM).
  Wind power constitutes a pivotal component in the quest for carbon neutrality, serving as a principal renewable energy source. Enhancing the accuracy of wind power forecasting facilitates more efficient exploitation of this resource, with deep-learning models,…
  pubmed Wang D, Xu M, Guangming Z, Luo F 等 2025 Feb 13 置信度 0.82
• Author Correction: An online monitoring method of milling cutter wear condition driven by digital twin.
  pubmed Zi X, Gao S, Xie Y 2025 Feb 13 置信度 0.82
• Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Current Tools, Techniques, and Uncharted Territories.
  Radiopharmaceutical therapy (RPT), with its targeted delivery of cytotoxic ionizing radiation, demonstrates significant potential for treating a wide spectrum of malignancies, with particularly unique benefits for metastatic disease. There is an opportunity to…
  pubmed Yusufaly T, Roncali E, Brosch-Lenz J, Uribe C 等 2025 Apr 1 置信度 0.82
• Digital Twins: The Future of Personalized Nutrition and Health?
  pubmed Abrahams M 2025 置信度 0.82