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• Testing the Limits of Biosignature Detection in Ca-sulphate Mixtures Through a Simulated Martian Environment
  Abstract Mixtures of cyanobacterial microbial mat and Ca-sulphate minerals were exposed to a simulated Martian environment via the Thales Alenia Space's “MARSBalloon” Project in partnership with St Bernard’s High School via the Orbyts science inclusivity progr…
  crossref Connor J. Ballard, Louisa J. Preston, Drashti Shah, Russell Hills 等 2023-11-29T16:32:56Z 置信度 0.70
• Abstract PD5-04: DCIS biosignature reclassified patients who met RTOG 9804 or ECOG-ACRIN E5194 ‘low-risk’ clinicopathologic criteria into an elevated invasive risk group who benefited significantly from radiation therapy
  Abstract Background: The goal of therapy for DCIS is to prevent invasive breast cancer. Randomized clinical trials for DCIS demonstrated that patients benefited from adjuvant radiation therapy (RT) after breast conserving surgery (BCS). However, treatment sele…
  crossref Frank Vicini, Chirag Shah, Steven Shivers, Weiwei He 等 2021-02-15T11:10:38Z 置信度 0.70
• The Spectroscopic Impact of Sublimation Under Martian Surface Conditions: Implications for Sample Analysis by the Rosalind Franklin Rover and Biosignature Preservation
  Abstract The 2028 ESA/NASA Rosalind Franklin Mission (RFM) will search for signs of past and present life in the shallow subsurface of Mars. It is crucial to understand how minerals and any biosignatures uncovered during these sampling activities might change …
  crossref Louisa J. Preston, Charles H. Minns, Ifigeneia Rousouli, Connor J. Ballard 等 2026-04-01T11:54:42Z 置信度 0.70
• Plasma Metabolomics Biosignature According to HIV Stage of Infection, Pace of Disease Progression, Viremia Level and Immunological Response to Treatment
  crossref Bruno Scarpelini, Michelle Zanoni, Maria Cecilia Araripe Sucupira, Hong-Ha M. Truong 等 2016-12-12T18:01:36Z 置信度 0.70
• Newly diagnosed iron deficiency anemia and subsequent autoimmune disease: a matched cohort study in Taiwan
  crossref Renin Chang, Kuo-An Chu, Mei-Chen Lin, Yi-Hsin Chu 等 2020-03-28T15:56:11Z 置信度 0.70
• Supplementary Figure S3 from The Stat3/5 Signaling Biosignature in Hematopoietic Stem/Progenitor Cells Predicts Response and Outcome in Myelodysplastic Syndrome Patients Treated with Azacitidine
  <p>Flow cytometric analyses of cellular hierarchy in Lin-CD34+ selected cells.</p>
  crossref Paraskevi Miltiades, Eleftheria Lamprianidou, Theodoros P. Vassilakopoulos, Sotirios G. Papageorgiou 等 2023-04-02T06:16:24Z 置信度 0.70
• Biosignature detection by Mars rover equivalent instruments in samples from the CanMars Mars Sample Return Analogue Deployment
  crossref Jessica M. Stromberg, Alexis Parkinson, Matthew Morison, Edward Cloutis 等 2019-06-14T23:23:32Z 置信度 0.70
• Supplementary Table S1 from The Stat3/5 Signaling Biosignature in Hematopoietic Stem/Progenitor Cells Predicts Response and Outcome in Myelodysplastic Syndrome Patients Treated with Azacitidine
  <p>Multivariate analysis of prognostic factors for overall survival in the patient cohort (n=74)</p>
  crossref Paraskevi Miltiades, Eleftheria Lamprianidou, Theodoros P. Vassilakopoulos, Sotirios G. Papageorgiou 等 2023-04-02T06:16:32Z 置信度 0.70
• Increased Risk of Parkinson Disease in Inflammatory Bowel Disease Patients
  crossref Shih-Wei Lai, Yu-Hung Kuo, Kuan-Fu Liao 2019-08-13T00:20:01Z 置信度 0.70
• Increased risk of autoimmune diseases in dengue patients: A population-based cohort study
  crossref Hao-Ming Li, Ying-Kai Huang, Yuan-Chih Su, Chia-Hung Kao 2018-05-07T12:57:34Z 置信度 0.70
• Weighted correlation network bioinformatics uncovers a key molecular biosignature driving the left-sided heart failure
  Abstract Background Left-sided heart failure (HF) is documented as a key prognostic factor in HF. However, the relative molecular mechanisms underlying left-sided HF is unknown. The purpose of this study is to unearth significant modules, pivotal genes and can…
  crossref Jiamin Zhou, Wei Zhang, Chunying Wei, Zhiliang Zhang 等 2020-07-03T02:14:56Z 置信度 0.70
• Supplementary Figure S2 from The Stat3/5 Signaling Biosignature in Hematopoietic Stem/Progenitor Cells Predicts Response and Outcome in Myelodysplastic Syndrome Patients Treated with Azacitidine
  <p>Significantly higher basal levels of Stat3 in patients with poor-risk cytogenetics.</p>
  crossref Paraskevi Miltiades, Eleftheria Lamprianidou, Theodoros P. Vassilakopoulos, Sotirios G. Papageorgiou 等 2023-04-01T16:30:07Z 置信度 0.70
• Supplementary Figure S5 from The Stat3/5 Signaling Biosignature in Hematopoietic Stem/Progenitor Cells Predicts Response and Outcome in Myelodysplastic Syndrome Patients Treated with Azacitidine
  <p>Pretreatment signaling profiles in clonal and non-clonal CD34+ progenitors.</p>
  crossref Paraskevi Miltiades, Eleftheria Lamprianidou, Theodoros P. Vassilakopoulos, Sotirios G. Papageorgiou 等 2023-04-02T06:16:27Z 置信度 0.70
• A CASE STUDY ON MICROBIAL COMMUNITIES AND BIOSIGNATURE PRESERVATION IN ACIDIC CAVE GYPSUM
  crossref Daniel Jones, Zoe E. Havlena, Heather V. Graham, Jennifer C. Stern 等 2024-10-29T22:42:11Z 置信度 0.70
• Cyst Fluid Biosignature to Predict Intraductal Papillary Mucinous Neoplasms of the Pancreas with High Malignant Potential
  crossref Ajay V. Maker, Vincent Hu, Shrihari S. Kadkol, Lenny Hong 等 2019-02-19T12:08:04Z 置信度 0.70
• Air Pollution Exposure and Risk of Spontaneous Pneumothorax in Children: A Longitudinal, Nationwide Study
  Spontaneous pneumothorax (SP) involves the spontaneous appearance of air in the pleural space. Atmospheric pressure, temperature change, and seasonal factors may precipitate SP, but its association with air pollution remains unclear. Therefore, we conducted th…
  europepmc Jing-Cheng Wang, Cheng-Li Lin, Chieh-Ho Chen, Chien-Heng Lin 2022 置信度 0.80
• Central venous catheter use increases ischemic stroke risk: a nationwide population-based study
  Abstract Background Central venous catheter (CVC) placement is a common procedure used for the treatment of critically ill patients. However, ischemic stroke is a complication after CVC placement. Aim This study investigated the association between CVC placeme…
  crossref P -H Liao, C -Y Lai, C -H Wu, Y -C Su 等 2019-06-12T23:14:30Z 置信度 0.70
• Stability of Amino Acids in Different Physical States under γ-Ray Irradiation and Implications for Mars Biosignature Detection
  crossref Xin Li, Qi-Tao Hu, Zi-Meng Zhou, Wen-Ping Liu 等 2026-03-24T04:40:40Z 置信度 0.70
• The Serum-Derived Extracellular Vesicle N-Glycome as a New Biosignature for Childhood Epilepsy
  crossref Yuanyuan Liu, Yanbin Guo, Changzhen Li, Zhiwen Huang 等 2025-12-19T07:55:36Z 置信度 0.70
• Bayesian Analysis for Remote Biosignature Identification on exoEarths (BARBIE). II. Using Grid-based Nested Sampling in Coronagraphy Observation Simulations for O ₂ and O ₃
  Abstract We present the results for the detectability of the O 2 and O 3 molecular species in the atmosphere of an Earth-like planet using reflected light at visible wavelengths. By quantifying the detectability as a function of the signal-to-noise ratio (S/N)…
  crossref Natasha Latouf, Avi M. Mandell, Geronimo L. Villanueva, Michael D. Himes 等 2023-12-20T06:01:08Z 置信度 0.70
• Nucleic acids and melanin pigments after exposure to high doses of gamma rays: a biosignature robustness test
  Abstract The question about the stability of certain biomolecules is directly connected to the life-detection missions aiming to search for past or present life beyond Earth. The extreme conditions experienced on extraterrestrial planet surface ( e.g. Mars), c…
  crossref A. Cassaro, C. Pacelli, M. Baqué, A. Maturilli 等 2022-07-06T06:42:16Z 置信度 0.70
• A Novel Biosignature Identifies Patients With DCIS With High Risk of Local Recurrence After Breast Conserving Surgery and Radiation Therapy
  crossref Frank A. Vicini, G. Bruce Mann, Chirag Shah, Sheila Weinmann 等 2022-09-15T00:10:46Z 置信度 0.70
• PON-1 carbamylation is enhanced in HDL of uremia patients
  crossref Chiz-Tzung Chang, Yun-Ping Lim, Chi-Wen Lee, Hsin-Yi Liao 等 2018-10-28T21:51:23Z 置信度 0.70
• Investigating the effects of gamma radiation on selected chemicals for use in biosignature detection instruments on the surface of Jupiter's moon Europa
  crossref Caroline Freissinet, Maëva Millan, Daniel P. Glavin, Xiang Li 等 2019-05-20T05:44:57Z 置信度 0.70
• Biosignature preparation for ocean worlds (BioPOW) instrument prototype
  In situ sampling missions to detect biosignatures on ocean worlds requires thorough sample preparation to manage the expected chemical complexity of such environments. Proposed instruments must be capable of automatic liquid sample handling to ensure sensitive…
  crossref Korine A. Duval, Tessa B. Van Volkenburg, Kathleen L. Craft, Chanel M. Person 等 2023-10-26T12:02:46Z 置信度 0.70
• PF537 THE STAT SIGNALING BIOSIGNATURE OF CD4+ T CELL SUBSETS REFLECT THE IMMUNOGENICITY OF HIGH‐RISK MDS AND PREDICT AZACYTIDINE TREATMENT OUTCOME
  Background: Azacytidine (AZA) is the mainstream treatment in high‐risk Myelodysplastic Syndromes (MDS), but the exact mechanism of action and resistance is largely unknown. AZA potentially acts, at least partially, by upregulating the antitumor immune response…
  crossref E. Lamprianidou, C. Kordella, E. Zoulia, M. Papoutselis 等 2019-06-17T13:52:21Z 置信度 0.70
• Abstract OT3-11-03: The PREDICT Registry Australia: A prospective registry to evaluate the clinical utility of a 7-gene predictive biosignature on treatment decisions in patients with ductal carcinoma in situ
  Abstract Background: For women with ductal carcinoma in situ (DCIS) treated with breast conserving surgery (BCS), the benefit of adjuvant radiation therapy (RT) remains controversial. Since there is level 1 evidence supporting the role of RT in reducing the ri…
  crossref Yvonne Zissiadis, G Bruce Mann, David Speakman, Christobel Saunders 等 2023-03-02T07:44:26Z 置信度 0.70
• Risk of Endometriosis and Subsequent Ovary and Breast Cancers in Nurses: A Population-Based Cohort Study in Taiwan
  Background: Endometriosis has been associated with the subsequent development of ovarian and breast cancers. This study evaluated whether nurses were at increased risks of developing endometriosis and subsequent ovarian and breast cancers. Methods: From Taiwan…
  crossref Hsing-Chi Hsu, Kai-Yu Tseng, Hsiang-Chi Wang, Fung-Chan Sung 等 2019-09-18T11:01:15Z 置信度 0.70
• Eukaryotic translation initiation factor 4E (eIF-4E) expressions are associated with poor prognosis in colorectal adenocarcinoma
  crossref Yi-Ting Chen, Hung-Pei Tsai, Chun-Chieh Wu, Jaw-Yuan Wang 等 2017-02-15T01:45:12Z 置信度 0.70
• High-sensitive troponin is associated with subclinical imaging biosignature of inflammatory cardiovascular involvement in systemic lupus erythematosus
  crossref Lea Winau, Rocio Hinojar Baydes, Axel Braner, Ulrich Drott 等 2018-08-04T18:25:12Z 置信度 0.70
• Association of iron deficiency anemia with tuberculosis in Taiwan: A nationwide population-based study
  crossref Kuo-An Chu, Chun-Hsiang Hsu, Mei-Chen Lin, Yi-Hsin Chu 等 2019-08-30T17:29:14Z 置信度 0.70
• Carbonate precipitation under bulk acidic conditions as a potential biosignature for searching life on Mars
  crossref David C. Fernández-Remolar, Louisa J. Preston, Mónica Sánchez-Román, Matthew R.M. Izawa 等 2012-08-23T23:47:25Z 置信度 0.70
• Risk of pneumonia among patients with splenectomy: a retrospective population-based cohort study
  crossref Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao 2017-10-17T12:15:45Z 置信度 0.70
• Identification of patients with DCIS with low-risk clinicopathology who benefit from radiation therapy with and without endocrine therapy after breast-conserving surgery assessed with the 7-gene biosignature.
  528 Background: Ductal carcinoma in situ (DCIS) accounts for 20% of breast cancers. For most patients with DCIS, the standard treatment involves breast-conserving surgery (BCS) followed by radiotherapy (RT). Adjuvant endocrine therapy (ET) is typically recomme…
  crossref Pat W. Whitworth, Chirag Shah, Frank Vicini, Rachel Rabinovitch 等 2024-05-29T16:01:20Z 置信度 0.70
• The Detectability and Constraints of Biosignature Gases in the Near- and Mid-infrared from Transit Transmission Spectroscopy
  Abstract The James Webb Space Telescope is expected to revolutionize our understanding of Jovian worlds over the coming decade. However, as we push toward characterizing cooler, smaller, terrestrial-like planets, dedicated next-generation facilities will be re…
  crossref L. Tremblay, M. R. Line, K. Stevenson, T. Kataria 等 2020-02-21T21:13:17Z 置信度 0.70
• THE INFLUENCE OF TEMPERATURE ON MICROBIAL COLONIZATION, CRATERS OF THE MOON NATIONAL MONUMENT, IDAHO: IMPLICATIONS FOR BIOSIGNATURE FORMATION WITHIN “SPECIAL REGIONS” ON MARS
  crossref Charity M. Phillips-Lander, Kayla M. Miller, Amanda M. Stockton, Elisabeth M. Hausrath 等 2016-10-20T18:06:14Z 置信度 0.70
• A Novel Biosignature to Assess Residual Risk in Early Stage Invasive Breast Cancer after Standard Breast Conserving Surgery
  crossref T. Bremer, C. Kesslering, R.R. Patel, S. Shivers 等 2020-10-23T19:22:28Z 置信度 0.70
• Proteomic analysis of human samples of irradiated tissue: Identification of a biosignature of radiation dose response
  crossref M ISBELL, C SCHWIETERT, R STERN, A JONES 等 2008-01-25T07:58:47Z 置信度 0.70
• Correction: Plasma Metabolomics Biosignature According to HIV Stage of Infection, Pace of Disease Progression, Viremia Level and Immunological Response to Treatment
  crossref Bruno Scarpellini, Michelle Zanoni, Maria Cecilia Araripe Sucupira, Hong-Ha M. Truong 等 2017-02-24T14:50:52Z 置信度 0.70
• Impact of Supratentorial Cerebral Hemorrhage on the Complexity of Heart Rate Variability in Acute Stroke
  Abstract Acute stroke commonly affects cardiac autonomic responses resulting in reduced heart rate variability (HRV). Multiscale entropy (MSE) is a novel non-linear method to quantify the complexity of HRV. This study investigated the influence of intracerebra…
  crossref Chih-Hao Chen, Sung-Chun Tang, Ding-Yuan Lee, Jiann-Shing Shieh 等 2018-07-25T09:17:25Z 置信度 0.70
• Evaluating the biosignature potential of nitrogen concentrations in graphite and associated K-silicates
  crossref Eva E. Stüeken, Kristoffer Szilas, Vincent J. van Hinsberg 2022-12-20T11:08:15Z 置信度 0.70
• A putative urinary biosignature for diagnosis and follow-up of tuberculous meningitis in children: outcome of a metabolomics study disclosing host–pathogen responses
  crossref Shayne Mason, A. Marceline Tutu van Furth, Regan Solomons, Ron A. Wevers 等 2016-06-10T07:15:14Z 置信度 0.70
• Preservation of Organic Matter in Aqueous Deposits and Soils Across the Mars‐Analog Qaidam Basin, NW China: Implications for Biosignature Detection on Mars
  Abstract A variety of aqueous deposits and soils from gullies, fluvial channels, mountain slopes, alluvial fans, playas, polygons, and yardangs have been found on Mars. However, the occurrence of sedimentary organic matter (SOM) in these landscapes under hyper…
  crossref Yan Chen, Jianxun Shen, Li Liu, Yu Sun 等 2022-12-12T05:33:53Z 置信度 0.70
• Life, Machine Learning, and the Search for Habitability: Predicting Biosignature Fluxes for the Habitable Worlds Observatory
  Future direct-imaging flagship missions, such as NASA's Habitable Worlds Observatory (HWO), face critical decisions in prioritizing observations due to extremely stringent time and resource constraints. In this paper, we introduce two advanced machine-learning…
  crossref Mark Moussa, Amber V. Young, Brianna Isola, Vasuda Trehan 等 2026-03-18T07:37:57Z 置信度 0.70
• Changes in the Raman and Fluorescence Spectroscopic Signatures of Irradiated Organic‐Mineral Mixtures: Implications for Molecular Biosignature Detection on Mars
  Abstract The search for potential molecular biosignatures on Mars is complicated by its harsh radiation environment that can alter or destroy the primary molecular features diagnostic of an organic compound's origins. In this work, mixtures of Mars‐relevant mi…
  crossref A. C. Fox, R. S. Jakubek, J. L. Eigenbrode 2023-02-02T10:38:17Z 置信度 0.70
• Non-invasive biosignature for CRSwNP: Therapeutic monitoring and recurrence prediction
  crossref S Müller, O Wendler, S Mayr, P Grundtner 等 2020-07-13T19:49:29Z 置信度 0.70
• Higher risk of developing a subsequent migraine in adults with nonapnea sleep disorders: A nationwide population-based cohort study
  crossref Tomor Harnod, Yu-Chiao Wang, Chia-Hung Kao 2015-03-29T12:47:01Z 置信度 0.70
• Wearable sensor (Parkinson’s Kinetigraph) and dopamine transporter imaging as potential biosignature for constipation in Parkinson’s (P2.8-006)
  crossref Daniel van Wamelen, Valentina Leta, Aleksandra Podlewska, Dhaval Trivedi 等 2023-12-07T09:59:43Z 置信度 0.70
• General Circulation Model Constraints on the Detectability of the CO₂-CH₄ Biosignature Pair on TRAPPIST-1e with JWST
  Abstract Terrestrial exoplanets such as TRAPPIST-1e will be observed in a new capacity with the JWST/Near Infrared Spectrograph (NIRSpec), which is expected to be able to detect CO 2 , CH 4 , and O 2 signals, if present, with multiple coadded transit observati…
  crossref Yoav Rotman, Thaddeus D. Komacek, Geronimo L. Villanueva, Thomas J. Fauchez 等 2022-12-28T11:25:38Z 置信度 0.70
• Hexagonal Platelet-like Magnetite as a Biosignature of Thermophilic Iron-Reducing Bacteria and Its Applications to the Exploration of the Modern Deep, Hot Biosphere and the Emergence of Iron-Reducing Bacteria in Early Precambrian Oceans
  Dissimilatory iron-reducing bacteria are able to enzymatically reduce ferric iron and couple to the oxidation of organic carbon. This mechanism induces the mineralization of fine magnetite crystals characterized by a wide distribution in size and irregular mor…
  crossref Yi-Liang Li 2012-11-12T10:48:05Z 置信度 0.70
• Cerebellar-limbic neurocircuit is the novel biosignature of physio-cognitive decline syndrome
  crossref Li-Kuo Liu, Kun-Hsien Chou, Chih-Chin Heather Hsu, Li-Ning Peng 等 2020-11-22T10:50:41Z 置信度 0.70
• Evaluating Habitability and Biosignature Detection on TOI-700 d: The Role of UV Environment and Atmospheric Pressure
  Abstract M dwarfs have long been prime targets in the search for habitable exoplanets, owing to their abundance in the Galaxy and the relative ease of detecting Earth-sized worlds within their narrower habitable zones. Yet, these low-mass stars can emit high-e…
  crossref Viktor Yuri Doná Sumida, Raissa Estrela, Adriana Valio 2025-11-28T04:51:03Z 置信度 0.70
• ACTH increment post total bilateral adrenalectomy for Cushing’s disease: a consistent biosignature for predicting Nelson’s syndrome
  crossref Liza Das, Anil Bhansali, Rosario Pivonello, Pinaki Dutta 等 2020-05-25T03:23:48Z 置信度 0.70
• Analytical validation of the 7-gene biosignature for prediction of recurrence risk and radiation therapy benefit for breast ductal carcinoma in situ
  Purpose Ductal carcinoma in situ (DCIS), is a noninvasive breast cancer, representing 20-25% of breast cancer diagnoses in the USA. Current treatment options for DCIS include mastectomy or breast-conserving surgery (BCS) with or without radiation therapy (RT),…
  europepmc David Dabbs, Karuna Mittal, Scott Heineman, Pat Whitworth 等 2023 置信度 0.80
• Increased Risk of Coronary Artery Disease in People with a Previous Diagnosis of Carpal Tunnel Syndrome: A Nationwide Retrospective Population-Based Case-Control Study
  Background . Existing literature suggests that an association exists between coronary artery disease (CAD) and carpal tunnel syndrome (CTS), but few researchers have explored whether CTS is a risk for CAD. Materials and Methods . This large case-control study …
  crossref Yi-Chuan Chang, Jen-Huai Chiang, Ing-Shiow Lay, Yu-Chen Lee 2019-03-03T18:32:22Z 置信度 0.70
• Controls on Reactive Oxygen Species Cycles in Yellowstone Hot Springs: Implications for Biosignature Preservation on Mars
  Early Earth and Mars had analogous environments. While life developed on our planet, the question of whether it did on Mars remains to be answered. Hot spring deposits are compelling targets for exploration because of their high habitability and potential to r…
  crossref Nancy W. Hinman, Megan A. Mave, Leanne C. Powers, Philippe Schmitt-Kopplin 等 2022-07-04T12:19:32Z 置信度 0.70
• CD4+ T Cells in High-Risk MDS Patients Bear an Aberrant STAT Signaling Biosignature
  Abstract CD4+ T cells hold a central role in tumor immunity by orchestrating and regulating antitumor responses. Azacytidine can apparently modulate tumor immunity in myelodysplastic syndrome (MDS) patients and affect CD4+ cell polarization, mainly in respondi…
  crossref Eleftheria Lamprianidou, Constantinos Tsatalas, Paraskevi Miltiades, Theodoros P. Vassilakopoulos 等 2019-10-10T03:05:42Z 置信度 0.70
• The Use of San-Huang-Xie-Xin-Tang Reduces the Mortality Rate among Breast Cancer Patients
  Globally, breast cancer is the most common cause of cancer deaths. In Taiwan, it is the most prevalent cancer among females. Since San-Huang-Xie-Xin-Tang (SHXXT) exerts not only an anti-inflammatory but an immunomodulatory effect, it may act as a potent anti-t…
  europepmc Daniel Winardi, Chieh-Hsin Wu, Jen-Huai Chiang, Yung-Hsiang Chen 等 2023 置信度 0.80
• Association between Breast Cancer and Second Primary Lung Cancer among the Female Population in Taiwan: A Nationwide Population-Based Cohort Study
  Purpose: A special association between breast cancer and second primary lung cancer in Taiwanese women has been discovered not only in clinical practice, but also in a large population-based study. We hereby investigate the association between breast cancer an…
  europepmc Fan-Wen Lin, Ming-Hsin Yeh, Cheng-Li Lin, James Wei 2022 置信度 0.80
• Selected plasma oxysterols as a potential multi-marker biosignature panel for Behçet’s Disease
  crossref Meriam Messedi, Wassim Guidara, Sahar Grayaa, Walid Khrouf 等 2022-05-16T18:46:47Z 置信度 0.70
• Characterization of the Halochromic Gloeocapsin Pigment, a Cyanobacterial Biosignature for Paleobiology and Astrobiology
  Ultraviolet (UV)-screening compounds represent a substantial asset for the survival of cyanobacteria in extreme environments exposed to high doses of UV radiations on modern and early Earth. Among these molecules, the halochromic pigment gloeocapsin remains po…
  crossref Yannick J. Lara, Andréa McCann, Cédric Malherbe, Camille François 等 2022-03-25T16:11:37Z 置信度 0.70
• ZIC-cHILIC Functionalized Magnetic Nanoparticle for Rapid and Sensitive Glycopeptide Enrichment from <1 µL Serum
  Due to their unique glycan composition and linkage, protein glycosylation plays significant roles in cellular function and is associated with various diseases. For comprehensive characterization of their extreme structural complexity occurring in >50% of hu…
  crossref Tiara Pradita, Yi-Ju Chen, Elias Mernie, Sharine Bendulo 等 2021-08-24T22:09:39Z 置信度 0.70
• A comparative study of in situ biosignature detection spectroscopy techniques on planetary surfaces
  crossref Kyle Uckert, Nancy J. Chanover, Stephanie Getty, William B. Brinckerhoff 等 2014-07-28T19:09:23Z 置信度 0.70
• Feasibility of Enceladus plume biosignature analysis: Successful capture of organic ice particles in hypervelocity impacts
  Abstract Enceladus is a compelling destination for astrobiological analyses due to the presence of simple and complex organic constituents in cryovolcanic plumes that jet from its subsurface ocean. Enceladus plume capture during a flyby or orbiter mission is a…
  crossref James S. New, Bahar Kazemi, Mark C. Price, Mike J. Cole 等 2020-09-04T08:17:01Z 置信度 0.70
• Erratum: “Alternative Methylated Biosignatures. I. Methyl Bromide, a Capstone Biosignature” (2022, ApJ, 938, 6)
  crossref Michaela Leung, Edward W. Schwieterman, Mary N. Parenteau, Thomas J. Fauchez 2025-06-20T10:43:52Z 置信度 0.70
• Slow degradation of ATP in simulated martian environments suggests long residence times for the biosignature molecule on spacecraft surfaces on Mars
  crossref Andrew C. Schuerger, Patricia Fajardo-Cavazos, Christopher A. Clausen, John E. Moores 等 2007-11-10T12:15:37Z 置信度 0.70
• Endolithic Mediation of Anhydrite in Hydrothermal Alteration Zones: Implications for Biosignature Exploration on Mars
  Abstract The formation of Ca‐sulfate minerals on Mars is believed to have been driven by hydrothermal alteration processes during the late Noachian. On Earth, microbial involvement in the crystallization of Ca‐sulfate minerals could contribute to the developme…
  crossref Yihao Xie, Geng Wu, Rong Li, Bingfu Yao 等 2025-10-25T13:00:04Z 置信度 0.70
• Association of anatase (TiO<sub>2</sub>) and microbes: Unusual fossilization effect or a potential biosignature?
  crossref Mihaela Glamoclija, Andrew Steele, Marc Fries, Juergen Schieber 等 2010-04-29T17:02:18Z 置信度 0.70
• Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding a biosignature (QUANTIFY): Protocol for a cross-sectional study
  crossref Zahra Amerian, Timothy Fleagle, Utsav Tuladhar, Barbara Van Gorp 等 2025-04-28T03:37:59Z 置信度 0.70
• Towards Integrated Astrophotonic Instruments for Exoplanet Biosignature Detection
  We present the design of integrated astrophotonic instruments for high background atmospheric gas detection. Such instruments can be fibre-coupled to long focal length space telescopes as compact, flexure-free, instruments.
  crossref Ross Cheriton, Adam Densmore, Suresh Sivanandam, Ernst de Mooij 等 2020-10-19T19:52:32Z 置信度 0.70
• Trace metal enrichments as a biosignature of modern and ancient hypersaline microbial mats
  crossref Jair Ceja-González, Jacob Valdivieso-Ojeda, Francisco Delgadillo-Hinojosa, Ronald Spelz-Madero 等 2026-07-10T00:21:46Z 置信度 0.70
• Abstract P4-02-02: Changes in treatment recommendation for patients with Ductal Carcinoma In Situ using a 7-gene predictive biosignature: Analysis of the PREDICT Study
  Abstract Background: The role of adjuvant radiotherapy (RT) following breast conserving surgery (BCS) for women with ductal carcinoma in situ (DCIS) remains controversial. Although there is Level 1 evidence supporting the use of RT in reducing the risk of loca…
  crossref Pat Whitworth, Steven C. Shivers, Chirag Shah, Rakesh Patel 等 2023-03-02T10:02:17Z 置信度 0.70
• Targeted Real-Time Assessment of Chronic Pain (TRAC-Pain) in Youth: Protocol for a Digital Biosignature Development Through a Prospective Observational Cohort Study (Preprint)
  BACKGROUND Approximately 1 in 5 children and adolescents live with chronic pain, with musculoskeletal (MSK) pain being one of the most prevalent subtypes. Unfortunately, some studies show that less than half of youth (<18 years) experience improvements …
  crossref Anna H Bailes, Chi-Hung Shu, Alan Chang, Sahrish Masood 等 2025-09-30T12:40:36Z 置信度 0.70
• Radiation Environment and Doses on Mars at Oxia Planum and Mawrth Vallis: Support for Exploration at Sites With High Biosignature Preservation Potential
  Abstract The first human missions on Mars will likely involve several astrobiology‐driven science operations, at sites with high biosignature preservation potential. Here, we present a study of the radiation environment induced by Galactic Cosmic Rays and Sola…
  crossref F. Da Pieve, G. Gronoff, J. Guo, C. J. Mertens 等 2020-11-20T23:17:24Z 置信度 0.70
• Agnostic Biosignature Exploration at Europa through Plume Sampling
  crossref Paul Mahaffy, Margaret Weng, Ricardo Arevalo, Mehdi Benna 等 2021-05-27T19:27:42Z 置信度 0.70
• Screening and identification of a six-cytokine biosignature for detecting TB infection and discriminating active from latent TB
  crossref Sen Wang, Yang Li, Yaojie Shen, Jing Wu 等 2018-07-20T12:32:40Z 置信度 0.70
• A framework for evaluating biosignature potential against the abiotic baseline on ocean worlds
  crossref Peter M. Higgins, Weibin Chen, Oliver Warr, Lucas M. Fifer 等 2026-06-17T09:04:41Z 置信度 0.70
• A 10-gene biosignature of tuberculosis treatment monitoring and treatment outcome prediction
  crossref Nguyen Phuoc Long, Nguyen Ky Phat, Nguyen Thi Hai Yen, Seongoh Park 等 2021-10-09T08:10:17Z 置信度 0.70
• Platelet miRNA Biosignature Discriminates between Dementia with Lewy Bodies and Alzheimer’s Disease
  Dementia with Lewy bodies (DLB) is one of the most common causes of degenerative dementia, after Alzheimer’s disease (AD), and presents pathological and clinical overlap with both AD and Parkinson’s disease (PD). Consequently, only one in three DLB cases is di…
  europepmc Ana Gámez-Valero, Jaume Campdelacreu, Dolores Vilas, Lourdes Ispierto 等 2021 置信度 0.80
• Determining the Detectability of H ₂ O with Photometric Observations Using Bayesian Analysis for Remote Biosignature Identification on exo-Earths (BARBIE)
  Abstract We examine the detectability of water (H 2 O) in the reflected-light spectrum of an Earth-like exoplanet assuming a photometric observational approach rather than spectroscopic. By quantifying the detectability as a function of normalized exposure tim…
  crossref Natasha Latouf, Chris Stark, Avi M. Mandell, Vincent Kofman 2026-01-08T09:16:51Z 置信度 0.70
• Detecting Land with Reflected-light Spectroscopy to Rule Out Waterworld O ₂ Biosignature False Positives
  Abstract The search for life outside our solar system is at the forefront of modern astronomy, and telescopes such as the Habitable Worlds Observatory (HWO) are being designed to identify biosignatures. Molecular oxygen, O 2 , is considered a promising indicat…
  crossref Anna Grace Ulses, Joshua Krissansen-Totton, Tyler D. Robinson, Victoria Meadows 等 2025-08-25T05:51:13Z 置信度 0.70
• Extracellular Vesicle Micrornas as an Epigenetic Biosignature of Arsenic-Associated Diabetes in the Strong Heart Study
  crossref Christian Ka'ikekuponoal Dye, Allison Kupsco, Gabriela L. Jackson, Ronald Alexander Glabonjat 等 2025-08-25T14:49:13Z 置信度 0.70
• A novel biosignature to assess residual risk in ductal carcinoma in situ (DCIS) patients after standard treatment.
  548 Background: There is an unmet need to identify women diagnosed with DCIS with elevated risk after standard treatment for whom enhanced treatment strategies should be considered. A response type (RSt) signature has been assessed in women treated with breast…
  crossref Troy Bremer, Chirag Shah, Rakesh Patel, Charlotta Wadsten 等 2020-05-25T15:15:43Z 置信度 0.70
• Discovery of Naturally Etched Fission Tracks and Alpha-Recoil Tracks in Submarine Glasses: Reevaluation of a Putative Biosignature for Earth and Mars
  Over the last two decades, conspicuously “biogenic-looking” corrosion microtextures have been found to occur globally within volcanic glass of the in situ oceanic crust, ophiolites, and greenstone belts dating back to ~3.5 Ga. These so-called “tubular” and “gr…
  crossref Jason E. French, David F. Blake 2016-02-17T17:12:47Z 置信度 0.70
• A plasma 3-marker microRNA biosignature distinguishes spinal tuberculosis from other spinal destructive diseases and pulmonary tuberculosis
  Accurate spinal tuberculosis (TB) diagnosis is of utmost importance for adequately treating and managing the disease. Given the need for additional diagnostic tools, this study aimed to investigate the utility of host serum miRNA biomarkers for diagnosing and …
  europepmc Qiang Liang, Weidong Jin, Zhigang Huang, Huquan Yin 等 2023 置信度 0.80
• IDENTIFYING PLANETARY BIOSIGNATURE IMPOSTORS: SPECTRAL FEATURES OF CO AND O ₄ RESULTING FROM ABIOTIC O ₂ /O ₃ PRODUCTION
  ABSTRACT O 2 and O 3 have been long considered the most robust individual biosignature gases in a planetary atmosphere, yet multiple mechanisms that may produce them in the absence of life have been described. However, these abiotic planetary mechanisms modify…
  crossref Edward W. Schwieterman, Victoria S. Meadows, Shawn D. Domagal-Goldman, Drake Deming 等 2016-02-25T15:41:33Z 置信度 0.70
• VNIR–mid-IR spectral signatures of abiotic and biogenic mixed-cation carbonates: implications for carbonate detection and biosignature assessment on Mars
  crossref Jasmijn van der Graaf, John F. Mustard, Christopher S. Romanek, Annemiek C. Waajen 等 2026-07-10T16:09:20Z 置信度 0.70
• What if we Find Nothing? Bayesian Analysis of the Statistical Information of Null Results in Future Exoplanet Habitability and Biosignature Surveys
  Abstract Future telescopes will survey temperate, terrestrial exoplanets to estimate the frequency of habitable ( η Hab ) or inhabited ( η Life ) planets. This study aims to determine the minimum number of planets ( N ) required to draw statistically significa…
  crossref Daniel Angerhausen, Amedeo Balbi, Andjelka B. Kovačević, Emily O. Garvin 等 2025-04-07T21:48:51Z 置信度 0.70
• A Biosignature Integrating Immune and Metabolic Signaling Axes to Assess Limited Radiation Therapy Response in Early-Stage Breast Cancer from a Low-Risk Cohort
  crossref T. Bremer, K. Mittal, F. Wärnberg, D. Dabbs 等 2023-09-29T18:29:46Z 置信度 0.70
• Scytonin in gypsum endolithic colonisation: First Raman spectroscopic detection of a new spectral biosignature for terrestrial astrobiological analogues and for exobiological mission database extension
  Microbial colonisations of gypsum from Eastern Poland (Badenian, Middle Miocene age) were investigated by Raman microspectrometry with a rarely used excitation 445 nm excitation. Zones of microbial colonisation in selenitic gypsum endolithic outcrops comp…
  pubmed Howell G. M. Edwards, Jan Jehlička, Kateřina Němečková, Adam Culka 等 2023 May 5 置信度 0.82
• The Effect of Spectral Resolution on Biosignature Detection via Reflected-light Observations of the Earth through Time
  Abstract NASA’s Habitable Worlds Observatory (HWO) will search for biosignatures on Earth-like exoplanets using reflected light spectroscopy. A critical instrument design parameter is resolving power, which must balance biosignature detectability against expos…
  crossref Samantha Gilbert-Janizek, Jacob Lustig-Yaeger, Joshua Krissansen-Totton 2026-08-05T09:06:09Z 置信度 0.70
• A High-pressure Filled Ice in the H ₂ O–CO ₂ –CH ₄ System, with Possible Consequences for the CO ₂ –CH ₄ Biosignature Pair
  Abstract Here we constrain the speciation of carbon that may outgas in ocean exoplanets. Ocean exoplanets likely have at least a few percent by mass of water, which is sufficient to build a high-pressure ice layer between a rocky interior and the outer hydrosp…
  crossref A. Levi, A. Bansal, D. Sasselov 2023-02-27T08:38:34Z 置信度 0.70
• Increased Risk of Peripheral Arterial Disease in Patients With Abdominal Aortic Aneurysm: A Retrospective Cohort Study (Version 5)
  Studies evaluating the risk of peripheral arterial disease (PAD) in patients with abdominal aortic aneurysm (AAA) are limited. We used insurance claims data of Taiwan to establish a cohort of 6590 patients with AAA newly diagnosed from 2000 to 2008 and 6590 co…
  crossref Yi-Ting Lin, Hsuan-Ju Chen, Pei-Chun Chen, Fung-Chang Sung 2018-02-15T00:41:57Z 置信度 0.70
• Organic Carbonyls Are Poor Biosignature Gases in Exoplanet Atmospheres but May Generate Significant CO
  Abstract The search for signs of life beyond Earth is a crucial driving motivation of exoplanet science, fueling new work on biosignature gases in habitable exoplanet atmospheres. We study carbonyls, a category of molecules containing the C=O double bond, foll…
  crossref Zhuchang Zhan, Jingcheng Huang, Sara Seager, Janusz J. Petkowski 等 2022-05-12T09:12:43Z 置信度 0.70
• Detecting Ce3+ as a biosignature mimicker using UV time-resolved laser-induced fluorescence and Raman spectroscopy: Implications for planetary missions
  crossref S. Shkolyar, E. Lalla, M. Konstantindis, K. Cote 等 2020-09-10T02:54:35Z 置信度 0.70
• Proteomic analysis of human samples of irradiated tissue: Identification of a biosignature of radiation dose response
  crossref M.A. Isbell, C.W. Schwietert, R.L. Stern, A. Jones 等 2004-09-14T17:03:33Z 置信度 0.70
• Sleep biosignature of Type 2 diabetes: a case–control study
  Abstract Aim To determine whether or not the sleep disturbances associated with Type 2 diabetes affect the structure of sleep. Methods We designed a case–control study in 76 patients with Type 2 diabetes and 76 control subjects without Type 2 diabetes, matched…
  crossref A. Lecube, O. Romero, G. Sampol, O. Mestre 等 2016-06-09T15:48:32Z 置信度 0.70
• A Protective Lipidomic Biosignature Associated with a Balanced Omega-6/Omega-3 Ratio in fat-1 Transgenic Mice
  crossref Giuseppe Astarita, Jennifer H. McKenzie, Bin Wang, Katrin Strassburg 等 2014-04-23T22:54:04Z 置信度 0.70
• Impact on Radiation Therapy Recommendation and Treatment Modality for Patients with Ductal Carcinoma In Situ Using the 7Gene Biosignature: Analysis of the PREDICT Study
  crossref C.S. Shah, P.W. Whitworth, S. Shivers, K. Mittal 等 2023-09-29T18:32:39Z 置信度 0.70
• Plasma Neurofilament Light Chain and Glial Fibrillary Acidic Protein Levels Are Prognostic of Disability Worsening: A Biosignature That Helps Differentiating Active From Non-active SPMS (2580)
  crossref Jens Kuhle, Aleksandra Maleska Maceski, Rolf Meinert, Inga Ludwig 等 2023-12-07T05:55:31Z 置信度 0.70