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• Characterization of Genetic Risk Factors of Cerebral Small Vessel Disease Based on Large-scale Transcriptome Profiling.
  europepmc 2026 置信度 0.80
• Bioinformatic identification of THY1 as a target in osteoarthritis and its effects on chondrocyte senescence and apoptosis.
  Osteoarthritis (OA) is the most prevalent degenerative joint disease worldwide and imposes a substantial public health burden due to the lack of effective disease-modifying drugs. Exosome-related genes participate in exosome biogenesis, cargo sorting, and secr…
  pubmed Huang L, Wen Y, Xu H, Zhang Z 等 2026 置信度 0.82
• Brain Spatial Genomics Atlases.
  europepmc 2026 置信度 0.80
• Genomics, Multi-Omics, and Emerging Artificial Intelligence for Combined Drought-Heat Stress Resilience in Plants: A Structured Narrative Review.
  europepmc 2026 置信度 0.80
• Integrated transcriptomic and metabolomic analysis of fluoride tolerance-related pathways and differentially expressed genes in silkworm strain XSKD.
  europepmc 2026 置信度 0.80
• CRISPR-enabled functional genomics for bolstering plant tolerance to abiotic and biotic stress; a comprehensive review.
  Climate change intensifies abiotic stresses including salinity, drought, and extreme temperatures alongside biotic threats such as pathogens and insect pests, collectively undermining global crop productivity and food security. Salinity and drought alone affec…
  europepmc Tahir Khan, Aamir Ali Abro, Usman Zulfiqar, Mohammed S. Alotaibi 等 2026 置信度 0.80
• Clinical application of genomic advances in systemic sclerosis.
  Systemic sclerosis (SSc) is a clinically heterogeneous chronic immune-mediated inflammatory disease with the highest mortality rate among all rheumatic diseases. Although current SSc clinical and serological classifications provide valuable prognostic informat…
  pubmed Rosa-Baez C, Rangel-Peláez C, Martínez-Gutiérrez L, Acosta-Herrera M 等 2026 置信度 0.82
• Assessing Genomic Competencies: Insights From the Genetics and Genomics Nursing Practice Survey (GGNPS).
  europepmc 2026 置信度 0.80
• Flywheel Genomics: Simultaneous trait discovery and genetic gain in plant breeding
  europepmc 2026 置信度 0.80
• Correction to: Cochlear synaptic vulnerability scales with pathological noise intensity in a noise-induced hearing loss model.
  europepmc 2026 置信度 0.80
• Enhancing Parents' Experiences of Paediatric Genomic Testing in Usual Outpatient Care: Insights From a Multi-Perspective Qualitative Study.
  europepmc 2026 置信度 0.80
• From polygenic risk to functional genomics: a framework for precision gynecological disease modeling.
  Gynecological conditions including endometriosis, polyendocrine metabolic ovarian syndrome and malignancies cause widespread chronic morbidity and infertility, yet translating genetic discoveries into biological mechanisms remains challenging. We propose a fra…
  pubmed Khatun M, Tapanainen JS, Salumets A 2026 置信度 0.82
• Opportunities and Challenges in Translating Genomics into Population Health Impact: Lessons from Familial Hypercholesterolemia.
  europepmc 2026 置信度 0.80
• Artificial Intelligence and Machine Learning Approaches for Cardiovascular Genomics: A State-of-the-Art Review.
  The advent of high-throughput sequencing technologies has revolutionized cardiovascular genetics, generating vast amounts of data. A major challenge in the genomic era is the efficient and accurate identification of causative genetic variants associated with c…
  pubmed De Paoli F, Nicora G, Galanti K, Gonzales CS 等 2026 置信度 0.82
• Pre-sampling conditions affect salivary genomic DNA yield and human DNA fraction: a single-donor pilot study.
  europepmc 2026 置信度 0.80
• Nurses' Genomic Knowledge, Attitudes, and Perceived Organizational Support: A Comparative Secondary Analysis of Genetics and Genomics in Nursing Practice Survey Data.
  europepmc 2026 置信度 0.80
• When genomics and histopathology diverge: insights from pathologic review of genomic-directed specimens.
  europepmc 2026 置信度 0.80
• Genomic and functional characterization of Rhizobium metallidurans NS41, a heavy-metal-resistant, non-legume-associated endophyte that reduces oxidative stress in metal-exposed maize.
  europepmc 2026 置信度 0.80
• Exploratory identification and cellular functional characterization of ppiabl as a candidate gene associated with growth traits in Paralichthys olivaceus.
  europepmc 2026 置信度 0.80
• A complete diploid human genome benchmark for personalized genomics.
  europepmc 2026 置信度 0.80
• Finishing a complete giraffe genome from telomere to telomere with Verkko-Fillet.
  europepmc 2026 置信度 0.80
• Systematic review and meta-analysis of circulating microRNAs in dengue infection: biomarkers, pathogenesis, and clinical implications.
  Dengue infection is a mosquito-borne disease that can cause mild illness or severe haemorrhagic fever. Predictive biomarkers for severe cases, especially those with bleeding manifestations or plasma leakage, are currently lacking. This systematic review and me…
  pubmed Venkatesan G, Wan Ab Rahman WS, Shahidan WNS, Ghazali N 等 2026 置信度 0.82
• Detection of the NPHP4 c.2999_3005del (p.Asn1000SerfsTer4) variant in an Iranian family with nephronophthisis-4.
  europepmc Motahareh Jadidi, Shima Booali, Kolsoum InanlooRahatloo 2026 置信度 0.80
• Integrative functional genomics maps synaptic and developmental-regulatory autism risk-gene sets across human cortex.
  europepmc Aojie Lian, Qiong Wang, Mei He, Hong Zhang 2026 置信度 0.80
• What has population genomics told us about the dynamics of selection and plant adaptation?
  europepmc 2026 置信度 0.80
• The use of artificial intelligence in advancing molecular biology in Africa: a narrative review.
  europepmc 2026 置信度 0.80
• Correction: Untargeted metabolomics reveals distinct metabolic profiles in MUT-type methylmalonic acidemia.
  europepmc 2026 置信度 0.80
• Comprehensive study of the tumor immune microenvironment and the prognostic significance of reticulocalbin-1: a pan-cancer analysis.
  europepmc 2026 置信度 0.80
• Sucrose and starch metabolism pathways as candidate regulatory pathways in the salt stress response revealed by transcriptomic and metabolomic analysis during soybean (Glycine max) germination.
  Soybean is a globally important grain and oil crop, and salt stress severely restricts its germination and seedling establishment, ultimately reducing yields. However, the core metabolic regulatory network underlying its salt-stress response and during seed ge…
  pubmed Zhang J, Wang Z, He X, Dong X 等 2026 置信度 0.82
• Another 10 years of PLOS Computational Biology: A data-driven reflection on trends in genomics research.
  europepmc 2026 置信度 0.80
• Correction: Platform-dependent performance of P2A and IRES linkers in multicistronic gene expression.
  europepmc 2026 置信度 0.80
• Lactate derived from CAFs mediates H3K18la in stemness gene promoters, which promotes tumor malignant phenotype formation.
  europepmc 2026 置信度 0.80
• Construction of a genetic linkage map and QTL mapping of growth-related traits in giant freshwater prawn, Macrobrachium rosenbergii.
  Growth-related traits are major determinants of production performance in the giant freshwater prawn, Macrobrachium rosenbergii, but their genetic architecture remains incompletely resolved. An F1 full-sib family of 133 individuals and two parents was analyzed…
  pubmed Wang T, Shen S, Dai X, Li Y 2026 置信度 0.82
• Genomic insights into specialized and primary metabolism gene clusters in methicillin-resistant Staphylococcus aureus from Egyptian community settings.
  europepmc 2026 置信度 0.80
• Unlocking the potential of genomics: a co-designed toolkit for hospital implementation and governance.
  Background Genomics is increasingly part of routine clinical care. However, hospital leaders face a range of organisational challenges in implementing safe, effective genomic care including: insufficient resources, rapidly evolving practices, gaps in genomic l…
  europepmc Belinda Dawson-McClaren, Cate Kelly, Trang Thu Do, Katie Arkell 等 2026 置信度 0.80
• Integrated profiling identifies NCOA3 as a prognostic factor in patients with glioma.
  Nuclear receptor coactivator 3 (NCOA3) is associated with various cancers, but its function and mechanism in glioblastoma multiforme (GBM) are still unclear. Bioinformatics analysis, in vitro cell experiments (NCOA3 silencing (si-NCOA3) or NCOA3 small-molecule…
  pubmed Luo Q, Yang J, Yin H, Yang M 等 2026 置信度 0.82
• Transcriptomic and RNAi analyses reveal chloride channel 3-associated osmoregulation in Litopenaeus vannamei under low-salinity stress.
  europepmc 2026 置信度 0.80
• Concurrent BCR::ABL1 and CBFA2T3::GLIS2 fusions in an adult patient with acute leukaemia.
  pubmed Huang J, Wu T, Zhu H, Li J 等 2026 置信度 0.82
• AI-enabled viral genomics: from virus discovery to host prediction and emerging variant forecasting.
  The rapid expansion of metagenomic sequencing has generated vast repositories of viral sequence data that far outpace our capacity to interpret them using conventional approaches. Highly divergent sequences, sparse functional annotation, and taxonomically unev…
  pubmed Ke J, Rong H, Chen Y, Zhu X 等 2026 置信度 0.82
• Genomic exploration of Serratia rubidaea MJ24 uncovers diverse biosynthetic capacity and agricultural relevance.
  europepmc 2026 置信度 0.80
• Integrative transcriptomic analysis and experimental validation identify GPR97 and PROK2 as novel genes upregulated in acute myocardial infarction.
  europepmc Yumin Meng, Qifan Chen, Jie Liu 2026 置信度 0.80
• Author Correction: Anti-inflammatory activity and antioxidant capacity of Clerodendrum japonicum (Thunb.) sweet extract in LPS-stimulated macrophages.
  europepmc 2026 置信度 0.80
• PangyPlot: multi-scale interactive visualization of pangenome variation graphs.
  europepmc 2026 置信度 0.80
• Decoding the decline of postmenopausal skeletal muscle.
  europepmc W. Glen Pyle 2026 置信度 0.80
• Decoding the senescent endothelial landscape in ischemic stroke through single-cell and bulk RNA sequencing.
  Ischemic stroke is a major cause of disability and mortality worldwide, but its underlying pathogenic mechanisms remain elusive. Although cellular senescence has been implicated in a wide range of age-related diseases, its specific contribution through endothe…
  pubmed Zhang L, Peng Y, Xiao B, Zhang M 2026 置信度 0.82
• Survivors' Responses to an Online Intervention to Promote Discussions of Cancer Genetic Risk with Blood Relatives.
  europepmc 2026 置信度 0.80
• TBGR-v2: an integrated pan-genome and evolutionary resource for Brassicaceae genomic research.
  europepmc 2026 置信度 0.80
• SeqQC-former: A sequence-quality fusion framework for QC-aware review prioritization of candidate somatic SNVs in cancer genomics.
  The accurate prioritization of candidate somatic single-nucleotide variants (SNVs) remains a challenge due to the substantial variability in sequencing quality across genomic loci. SeqQC-Former is a sequence-quality fusion framework that integrates the local n…
  pubmed Zubair M, Li J, Wang Z, Qian J 2026 置信度 0.82
• Characteristics, comparative genomics, and phylogenetic analysis of the chloroplast genome of <i>Rosaplatyacantha</i>.
  europepmc 2026 置信度 0.80
• From Genetics to Functional Genomics: Redefining Susceptibility in Takotsubo Syndrome.
  europepmc 2026 置信度 0.80
• Integrated bulk and single-cell transcriptomic analyses identify senescence-related hub genes and microenvironmental remodeling in sarcopenia.
  europepmc 2026 置信度 0.80
• Filling the holes in whole genomes: A vision for personalized genomics from telomere to telomere.
  europepmc 2026 置信度 0.80
• GEAR Genomics: a user-friendly, open-source web platform enabling interactive genomic analysis for molecular biologists.
  europepmc 2026 置信度 0.80
• Agentic AI for trustworthy synthetic microbial genomics: a perspective on generation, validation, and governance.
  europepmc 2026 置信度 0.80
• Using SMART Goals to Support Genomic Integration in Nursing Education.
  Persistent gaps in faculty capacity hinder the integration of genomics into nursing curricula, highlighting the need for strengthened faculty development.
  pubmed Connors LM, Friend P, Kelly PA 2026 置信度 0.82
• Key Outcomes from a Stakeholder Workshop on Genomic Newborn Screening: Recommended Next Steps for the Integration of Genomics into Public Health Programs.
  europepmc 2026 置信度 0.80
• Genomics is modifying our concepts of evolution in homosporous and heterosporous vascular plants.
  europepmc 2026 置信度 0.80
• Canonically minimal RNA-guided insertion sequences expand into large elements that disseminate antimicrobial resistance
  europepmc 2026 置信度 0.80
• Bubbles, rats and resilience: gene transcripts provide clues to tolerance of venous gas emboli and decompression stress.
  europepmc 2026 置信度 0.80
• The Silicon Microbial Community.
  europepmc 2026 置信度 0.80
• Integrated genome-wide high-throughput screening and functional validation identifies Sm proteins as essential splicing regulators for gastric cancer progression.
  europepmc 2026 置信度 0.80
• Genome-wide identification, characterization, and expression analysis of the glutathione peroxidase (GPX) gene family in Siniperca chuatsi.
  europepmc 2026 置信度 0.80
• Whole-genome sequencing reveals adaptive strategies of the Antarctic aquatic bacterium Arthrobacter sp. R5.
  europepmc Alessia Levante, Annarita De Felice, Camilla Lazzi, Alessandro Coppola 等 2026 置信度 0.80
• Emerging Principles in Spatial Functional Genomics.
  europepmc 2026 置信度 0.80
• Complete genome sequence of a novel Winogradskyella species isolated from deep-sea sponge reveals a β-propeller phytase.
  europepmc 2026 置信度 0.80
• Corrigendum to "RASSF6-TRIM16 axis promotes cell proliferation, migration and invasion in esophageal squamous cell carcinoma" [J. Genet. Genom. (2019) 46(10), 477-488].
  europepmc 2026 置信度 0.80
• Next-generation insect digitization: combining phenomics and genomics by subsequent synchrotron X-ray imaging and DNA sequencing
  europepmc 2026 置信度 0.80
• Response to Quinodoz and Leroy.
  europepmc 2026 置信度 0.80
• Distinct molecular responses to acute cold exposure revealed by comparative transcriptomic and metabolomic profiling in the bay scallop Argopecten irradians.
  europepmc 2026 置信度 0.80
• Evaluating the impact of SDHAF3 p.F53L genetic variant on clinically significant QTc prolongation in patients prescribed high-risk medications: a retrospective pharmacogenetic study.
  europepmc 2026 置信度 0.80
• Cross-species functional transcriptomic analysis distinguishes conserved aging-niche remodeling from inflammatory fibroblast heterogeneity in cardiac aging and heart failure.
  europepmc Yimeng LI 2026 置信度 0.80
• Comparative pan-genomics reveals pervasive lineage-specific innovations and improves cross-species synteny inference in cereals.
  europepmc 2026 置信度 0.80
• Evolutionary characterization and expression profiling of ACC and FASN genes in Chinese mitten crab Eriocheir sinensis.
  europepmc 2026 置信度 0.80
• Allelic Survey and Population Genomics in a Hotspot of Diflubenzuron Resistance in the Mosquito <i>Culex pipiens</i>.
  europepmc 2026 置信度 0.80
• Integrated Comparative Genomics and Population Genomics Reveal the Genomic and Epigenomic Basis of Barley (<i>Hordeum vulgare</i>) Evolution and Domestication.
  Barley ( Hordeum vulgare ) is one of the earliest domesticated cereal crops and remains important for global feed, food, and malting industries. Although high-quality genomic resources are now available, its large repeat-rich genome has complicated genome-wide…
  europepmc 2026 置信度 0.80
• Structural Genomics Defines PBRM1 Bromodomain Variant Function in ccRCC.
  europepmc 2026 置信度 0.80
• Advances in Functional Genomics for Human Health.
  europepmc 2026 置信度 0.80
• Digest: Between yellow and orange: genomics of hybridization in Colias butterflies.
  europepmc 2026 置信度 0.80
• Understanding hypertensive renal injury: a well-structured approach.
  europepmc Peter A. Doris 2026 置信度 0.80
• Identification and characterization of G protein-coupled receptors in the nocturnal halictid bee Megalopta genalis.
  europepmc 2026 置信度 0.80
• The LncRNA-Tumor Immune Microenvironment Nexus: Integrative Insights for Cancer Immunotherapy.
  europepmc 2026 置信度 0.80
• Causal Interplay Between Platelet Indices and Rheumatoid Arthritis: Genetic Evidence From Bidirectional Mendelian Randomization.
  Objectives This study is aimed at comprehensively understanding genetically causal associations between some platelet indices (PIs) and rheumatoid arthritis (RA). Methods Genetic summary statistics for the 4 types of PIs and RA were derived from Neale Lab, Fin…
  europepmc Xu-Yan Shen, Jia-Ying Sun, Xin Wang, Shu-Shan Zhao 2026 置信度 0.80
• Phylogenetic analysis of the bacterial intracellular R-body killer proteins indicates extensive horizontal gene transfer and signature Reb sequence motifs.
  europepmc 2026 置信度 0.80
• A Comprehensive Comparative Analysis of Sequence-Based Deep Learning Models for Single-Cell Genomics.
  europepmc 2026 置信度 0.80
• Association of UGT and CYP genotype-predicted activity with tyrosine kinase inhibitor toxicity.
  europepmc 2026 置信度 0.80
• A real-time PCR-based noninvasive prenatal RHD screening assay optimized for population-specific RHD allelic spectra in China.
  europepmc 2026 置信度 0.80
• Recurrent PIK3CA-E545K mutation promotes cervical cancer growth and invasion via AKT/mTOR signaling.
  europepmc 2026 置信度 0.80
• Integrated transcriptomic and metabolomic analysis suggests β-alanine and arachidonic acid metabolism are associated with salinity stress adaptation in red tilapia.
  europepmc 2026 置信度 0.80
• Systems-level genomic analyses reveal shared mechanisms underlying endometriosis and sleep disorders.
  europepmc Licong Shen, Jun Chen, Yongwen Yang 2026 置信度 0.80
• Potential for Genomics to Help Guide Preventive Strategies in Psychiatry.
  europepmc 2026 置信度 0.80
• SorghumHub: featuring the next phase for the KBCommons web portal with new molecular biology features.
  europepmc 2026 置信度 0.80
• FERONIA: Organizing plant thermotolerance from the cell surface.
  europepmc 2026 置信度 0.80
• Corrigendum to "Heterogeneity of fibroblasts from different anatomical sites in healthy human knee ligaments revealed by single-cell RNA sequencing" [Genomics 117 (2025), 111040].
  pubmed Zhao H, Yao Y, Jiang F, Zhu X 等 2026 置信度 0.82
• Promises and Pitfalls of Long-Read Sequencing for Resolving Microbial Complexity.
  Long-read sequencing (LRS) has driven a transition in microbial genomics, overcoming the assembly fragmentation inherent to short-read sequencing. This review elucidates the impact of LRS across isolate genomics, metagenomics, and multi-omics domains. By spann…
  pubmed Rao X (饶兴), Gu Y (顾雨铮), Gabriella, Ma J (马嘉仪) 等 2026 置信度 0.82
• Genome-wide scans reveal candidate genes associated with wing morph differentiation in Tetrix japonica.
  europepmc 2026 置信度 0.80
• The HTR2A rs6311 and rs6313 polymorphisms and atypical antipsychotics response in schizophrenia: a scoping review.
  The HTR2A polymorphisms rs6311 (A-1438G) and rs6313 (T102C) have been thoroughly studied for their impact on atypical antipsychotics (AAPs) responsiveness in schizophrenia. However, the results remain inconsistent owing to the complex genetic and pharmacodynam…
  pubmed Hidayah N, Ikawati M, Amin MM, Ikawati Z 2026 置信度 0.82
• Molecular characterization of 16 MAPK genes in silver carp (Hypophthalmichthys molitrix) and the differences of their mRNA expression between Qiandao Lake and Taihu Lake.
  europepmc 2026 置信度 0.80
• Umbilical Cord: A Non-Invasive DNA Source for Sea Turtle Genomics.
  europepmc 2026 置信度 0.80
• GmNIGT2a/2b-mediated transcriptional cascade buffers high-nitrogen-triggered nodule senescence in soybean.
  europepmc 2026 置信度 0.80
• Virus-induced gene silencing as a tool for functional genomics in weeds: Challenges and future directions.
  europepmc 2026 置信度 0.80