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• Simplifications and approximations in molecular systems biology: lessons from a single-gene circuit
  preprints 2024 置信度 0.74
• RBC-GEM: a Knowledge Base for Systems Biology of Human Red Blood Cell Metabolism
  Abstract Advancements with cost-effective, high-throughput omics technologies have had a transformative effect on both fundamental and translational research in the medical sciences. These advancements have facilitated a departure from the traditional view of …
  preprints Zachary B. Haiman, Angelo D’Alessandro, Bernhard O. Palsson 2024 置信度 0.74
• Systems Biology-Based Assessment of Immune Responses to Whole Cell and Acellular Pertussis Vaccines: Rationale, Methodology and Enrollment Procedures for Omics Workflows
  preprints 2024 置信度 0.74
• A novel architecture for collaboration in systems biology at the age of the Metaverse
  preprints 2023 置信度 0.74
• Determining the link between psoriasis and Crohn's disease using bioinformatics and systems biology approaches
  preprints 2024 置信度 0.74
• Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF)
  preprints 2024 置信度 0.74
• Identifying Representative Cell Line Models for TNBC Chemotherapy Drug Resistance via Systems Biology and Bioinformatics
  preprints 2024 置信度 0.74
• Identification of Cross-Cancer Biomarkers: COMP mRNA and CARMN/GSEC lncRNAs Shared in Breast, Gastric, and Colorectal Cancers via Integrated Systems Biology and Experimental Validation
  preprints 2025 置信度 0.74
• Exploration of the link between COVID-19 and gastric cancer from the perspective of bioinformatics and systems biology
  preprints 2024 置信度 0.74
• Evolutionary Systems Biology Identifies Genetic Trade-offs In Rice Defense Against Above- and Belowground Attackers
  Abstract Like other plants, wild and domesticated rice species ( Oryza nivara, O. rufipogon , and O. sativa ) evolve in environments with various biotic and abiotic stresses that fluctuate in intensity through space and time. Microbial pathogens and invertebra…
  preprints Taryn S. Dunivant, Damaris Godinez-Vidal, Craig Perkins, Madelyn G. Lee 等 2024 置信度 0.74
• An analysis of natural variation in <i>Pinus pinaster</i> through the lens of systems biology
  preprints 2024 置信度 0.74
• Reprogramming of Energy Metabolism in Human <em>PKD1</em> Polycystic Kidney Disease: A Systems Biology Analysis
  preprints 2024 置信度 0.74
• Investigation of novel regulatory mechanisms of TRIM29 in BC, GC, and CRC patients: systems biology approach to find novel non-coding interactions
  preprints 2024 置信度 0.74
• Linear and Nonlinear Modes & Data Signatures in Dynamic Systems Biology Models
  preprints 2023 置信度 0.74
• From CFTR to a CF signalling network: a systems biology approach to study Cystic Fibrosis
  preprints 2023 置信度 0.74
• WITHDRAWN: Elucidating the molecular mechanism of phytochemicals against Parkinson’s disease through an integrated systems biology and molecular modeling approach
  preprints 2024 置信度 0.74
• Identification of Key Ischemic Stroke Genes by Computational Systems Biology
  preprints 2023 置信度 0.74
• WITHDRAWN: Mechanistic modeling of Mycobacterium tuberculosis β-carbonic anhydrase inhibitors using integrated systems biology and the QSAR approach
  preprints 2024 置信度 0.74
• Unveiling Novel Regulatory Mechanisms of BEX1 in Breast, Gastric, and Colorectal Cancer via a Systems Biology Approach: The Roles of lncRNAs COLCA1 and GAS6-AS1 and Their Interactions
  preprints 2024 置信度 0.74
• Stress Knowledge Map: A knowledge graph resource for systems biology analysis of plant stress responses
  preprints 2023 置信度 0.74
• Studying stochastic systems biology of the cell with single-cell genomics data
  preprints 2023 置信度 0.74
• An integrated systems-biology platform for power-to-gas technology
  preprints 2022 置信度 0.74
• Inclusive pedagogy strategies to introduce high schoolers to systems biology
  preprints 2023 置信度 0.74
• Key gene modules and hub genes associated with pyrethroid and organophosphate resistance in Anopheles mosquitoes: A systems biology approach
  preprints 2024 置信度 0.74
• Systems Biology and Cytokines Potential Role in Lung Cancer Immunotherapy Targeting Autophagic Axis
  preprints 2023 置信度 0.74
• Systems Biology in Cancer Diagnosis Integrating Omics Technologies and Artificial Intelligence to support physician decision-making
  preprints 2023 置信度 0.74
• Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice ( <i>Oryza sativa</i> ) using an ensemble network-based systems biology approach
  preprints 2024 置信度 0.74
• SBOannotator: a Python Tool for the Automated Assignment of Systems Biology Ontology Terms
  preprints 2023 置信度 0.74
• RNA interaction and expression analysis of UHRF1 in breast cancer, gastric cancer, and colorectal cancer patients: systems biology investigation and experimental validation
  preprints 2024 置信度 0.74
• A systems biology-based study to assess the effects of TNF-α ± apigenin in triple-negative breast cancer cell line
  preprints 2024 置信度 0.74
• RGS2-related non-coding interaction network modulates the NF-Kappa B signaling pathway in MS patients: a systems biology investigation
  preprints 2024 置信度 0.74
• LncRNA PAN3-AS1 modulates cilium assemble signaling pathway through regulation of RPGR as a potential MS diagnostic biomarker: integrated systems biology investigation
  preprints 2024 置信度 0.74
• LINC01132 and LINC02542 modulate the PIK3/ACT signaling pathway in colorectal cancer patients through regulation of IGF2: a systems biology-based biomarker discovery
  preprints 2024 置信度 0.74
• Identification of metabolic pathways and key genes associated with Atypical Parkinsonism using a systems biology approach
  preprints 2023 置信度 0.74
• Integrative systems biology framework discovers common gene regulatory signatures in multiple mechanistically distinct inflammatory skin diseases.
  preprints 2023 置信度 0.74
• Integrative systems biology framework discovers common gene regulatory signatures in multiple mechanistically distinct inflammatory skin diseases
  ABSTRACT Aim More than 20% of the population across the world is affected by non-communicable inflammatory skin diseases including psoriasis, atopic dermatitis, hidradenitis suppurativa, rosacea, etc. Many of these chronic diseases are painful and debilitating…
  preprints Bharat Mishra, Mohammad Athar, M. Shahid Mukhtar 2023 置信度 0.74
• A systems biology approach reveals the endocrine disrupting potential of Aflatoxin B1.
  preprints 2022 置信度 0.74
• ISRES+: An improved evolutionary strategy for function minimization to estimate the free parameters of Systems Biology models
  preprints 2023 置信度 0.74
• Computational Systems Biology in Disease Modeling and Control, Review and Perspectives
  preprints 2022 置信度 0.74
• Predictive Systems Biology Modeling: Unraveling Host Metabolic Disruptions and Potential Drug Targets in Acute Viral Infections
  preprints 2023 置信度 0.74
• Unraveling Coinfection Dynamics into 100 Whole Genome of Diarrheal Pathogens: A Genome-to-Systems Biology Approach with <i>Plesiomonas shigelloides</i>
  preprints 2023 置信度 0.74
• Deciphering the Molecular Mechanisms Underlying the Psoriasis and T2D: A Systems Biology Approach Using Microarray Data Analysis
  preprints 2023 置信度 0.74
• Investigating Molecular Aspects of SARS-CoV-2 Neurological Manifestations, a Systems Biology Approach
  preprints 2022 置信度 0.74
• Exploration of the Link Between COVID-19 and Alcoholic Hepatitis from the Perspective of Bioinformatics and Systems Biology
  preprints 2023 置信度 0.74
• Systems biology illuminates alternative metabolic niches in the human gut microbiome
  preprints 2022 置信度 0.74
• Integration of Mendelian randomisation and systems biology models to identify novel blood-based biomarkers for stroke
  preprints 2023 置信度 0.74
• Systems biology and machine learning approaches identify metabolites that influence dietary lifespan and healthspan responses across flies and humans
  preprints 2023 置信度 0.74
• Molecular profiling of high-level athlete skeletal muscle after acute exercise – a systems biology approach
  preprints 2023 置信度 0.74
• PanomiR: A systems biology framework for analysis of multi-pathway targeting by miRNAs
  preprints 2022 置信度 0.74
• Bayesian hypothesis testing reveals that reproducible models in Systems Biology get more citations
  preprints 2022 置信度 0.74
• Aquamoleculomics: A Thermodynamic Cornerstone of Systems Biology
  Systems biology has been established for more than a decade in the post-genomic era. With the help of the computational and mathematical tools, systems biology reconstitutes the entire scenario of the cell, tissue and even organism from the pieces data generat…
  preprints Zilin Nie, Yanming Nie 2021 置信度 0.74
• Spatial cancer systems biology resolves heterotypic interactions and identifies disruption of spatial hierarchy as a pathological driver event
  preprints 2023 置信度 0.74
• Modular assembly of dynamic models in systems biology
  Abstract It is widely acknowledged that the construction of large-scale dynamic models in systems biology requires complex modelling problems to be broken up into more manageable pieces. To this end, both modelling and software frameworks are required to enabl…
  preprints Michael Pan, Peter J. Gawthrop, Joseph Cursons, Edmund J. Crampin 2021 置信度 0.74
• A Systems Biology Approach to Pathogenesis of Gastric Cancer: Gene Network Modeling and Pathway Analysis
  Abstract Introduction Gastric cancer (GC) ranks among the most common malignancies worldwide. In our previous study, we found overexpressed genes in GC clinical samples. The goal of the current study was to find critical genes and key pathways involved in the …
  preprints Negar Mottaghi-Dastjerdi, Abozar Ghorbani, Hamed Montazeri 2022 置信度 0.74
• High Efficiency Rare Earth Element Biomining with Systems Biology Guided Engineering of <i>Gluconobacter oxydans</i>
  preprints 2023 置信度 0.74
• A General SBML Compatible Hybrid Modeling Framework: Combining Biochemical Mechanisms with Deep Neural Networks for Systems Biology Applications
  preprints 2023 置信度 0.74
• SBMate: A Framework for Evaluating Quality of Annotations in Systems Biology Models
  preprints 2021 置信度 0.74
• The Systems Biology Simulation Core Library
  preprints 2020 置信度 0.74
• Reproducibility in systems biology modelling
  preprints 2020 置信度 0.74
• Identification of Key Ischemic Stroke Genes by Computational Systems Biology
  preprints 2021 置信度 0.74
• A systems biology approach to elucidate the post-translational regulome of coronary artery disease
  preprints 2022 置信度 0.74
• Genetic Algorithm with Rank Selection optimises robust parameter estimation for systems biology models
  preprints 2022 置信度 0.74
• NLoed: A Python package for nonlinear optimal experimental design in systems biology
  preprints 2021 置信度 0.74
• Systems Biology Approach of Understanding Insulin Resistance: Linkage between Type 2 Diabetes & Alzheimer’s Disease
  preprints 2022 置信度 0.74
• Advice from a systems-biology model of the Corona epidemics
  preprints 2020 置信度 0.74
• Advice from a systems-biology model of the Corona epidemics
  preprints 2020 置信度 0.74
• A clinically validated human saliva metatranscriptomic test for global systems biology studies
  preprints 2021 置信度 0.74
• <i>Microbench</i> : Automated metadata management for systems biology benchmarking and reproducibility in Python
  Abstract Motivation Computational systems biology analyses typically make use of multiple software and their dependencies, which often run across heterogeneous compute environments. This can introduce differences in performance and reproducibility. Capturing m…
  preprints Alexander L. R. Lubbock, Carlos F. Lopez 2021 置信度 0.74
• A systems biology-based identification and <i>in vivo</i> functional screening of Alzheimer’s disease risk genes reveals modulators of memory function
  preprints 2022 置信度 0.74
• Entropic Systems Biology: A Novel Thermodynamic Theory for the Modernization of Traditional Chinese Medicine
  preprints 2021 置信度 0.74
• BioKC: a collaborative platform for systems biology model curation and annotation
  Curation of biomedical knowledge into standardised and inter-operable systems biology models is essential for studying complex biological processes. However, systems-level curation is a laborious manual process, especially when facing ever increasing growth of…
  preprints Carlos Vega, Valentin Grouès, Marek Ostaszewski, Reinhard Schneider 等 2020 置信度 0.74
• dSeqSb: A systems biology approach to decipher dynamics of host-pathogen interactions using temporal dual RNA-seq data
  preprints 2022 置信度 0.74
• SBMLWebApp: Web-based Simulation, Steady-State Analysis, and Parameter Estimation of Systems Biology Models
  preprints 2021 置信度 0.74
• Integrative Systems Biology Approaches to Identify Potential Biomarkers and Pathways of Cervical Cancer
  preprints 2021 置信度 0.74
• Evolutionary systems biology reveals patterns of rice adaptation to drought-prone agro-ecosystems
  preprints 2021 置信度 0.74
• Systems biology analysis identifies TCF7L1 as a key regulator of metastasis in Ewing sarcoma
  preprints 2021 置信度 0.74
• Identifiability analysis for stochastic differential equation models in systems biology
  preprints 2020 置信度 0.74
• A systems biology approach to disentangle the direct and indirect effects of global transcription factors on gene expression in <i>Escherichia coli</i>
  preprints 2022 置信度 0.74
• Systems Biology under heat stress in Indian Cattle
  preprints 2020 置信度 0.74
• Systems Biology Analysis of Human Genomes Points to Key Pathways Conferring Spina Bifida Risk
  preprints 2021 置信度 0.74
• Endocrine disrupting chemicals and COVID-19 relationships: a computational systems biology approach
  preprints 2020 置信度 0.74
• Chemical Systems Biology Reveals Mechanisms of Glucocorticoid Receptor Signaling
  preprints 2020 置信度 0.74
• Deciphering The Molecular Pathogenesis Behind Neurological Manifestations of SARS-CoV-2 And Drug Repurposing, A Systems Biology Approach
  preprints 2021 置信度 0.74
• A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
  preprints 2020 置信度 0.74
• A systems biology analysis of adrenergically stimulated adiponectin exocytosis in white adipocytes
  preprints 2020 置信度 0.74
• Anti-cancer Potential of <i>Moringa oleifera</i> on BRCA1 Gene: Systems Biology
  preprints 2020 置信度 0.74
• LINC00520 promotes breast cancer development by low expression as a tumor suppressor and prognostic biomarker by regulating the ESR2 expression level: integrated systems biology bioinformatics and experimental analyses
  preprints 2022 置信度 0.74
• Transcription analysis of the THBS2 gene through regulation by potential non-coding diagnostic biomarkers and oncogenes of gastric cancer in the ECM receptor interaction signaling pathway: integrated systems biology and experimental investigation
  preprints 2022 置信度 0.74
• Integrative systems biology approach identified crucial genes and transcription factors associated with gallbladder cancer pathogenesis
  preprints 2021 置信度 0.74
• Prediction of Chemoresistance Trait of Cancer Cell Lines using Machine Learning Algorithms and Systems Biology Analysis
  preprints 2021 置信度 0.74
• Parallel Tempering with Lasso for Model Reduction in Systems Biology
  Abstract Systems Biology models reveal relationships between signaling inputs and observable molecular or cellular behaviors. The complexity of these models, however, often obscures key elements that regulate emergent properties. We use a Bayesian model reduct…
  preprints Sanjana Gupta, Robin E.C. Lee, James R. Faeder 2019 置信度 0.74
• Novel antiviral interferon sensitive genes unveiled by correlation-driven gene selection and integrated systems biology approaches
  preprints 2021 置信度 0.74
• Long non-coding RNAs bind to proteins relevant to the ethanol tolerance in yeast: a systems biology view
  preprints 2021 置信度 0.74
• GPSRdocker: A Docker-based Resource for Genomics, Proteomics and Systems biology
  preprints 2019 置信度 0.74
• DIA-based systems biology approach unveils novel E3-dependent responses to a metabolic shift
  preprints 2020 置信度 0.74
• An integrative systems biology approach to identify the molecular basis of sperm quality in swine
  preprints 2020 置信度 0.74
• A comprehensive investigation of colorectal cancer progression, from the early to late-stage, a systems biology approach
  Abstract Colorectal cancer is a widespread malignancy with a concerning mortality rate. It could be curable at the first stages, but the progress of the disease and reaching to the stage-4 could make shift the treatments from curative to palliative. In this st…
  preprints Mohammad Ghorbani, Yazdan Asgari 2020 置信度 0.74
• Systems biology informed deep learning for inferring parameters and hidden dynamics
  preprints 2019 置信度 0.74
• Integrating ensemble systems biology feature selection and bimodal deep neural network for breast cancer prognosis prediction
  preprints 2021 置信度 0.74
• A Multidimensional Systems Biology Analysis of Cellular Senescence in Ageing and Disease
  preprints 2019 置信度 0.74