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preprints
2025
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preprints
2026
置信度 0.74
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Abstract Background The cBAF SWI/SNF chromatin remodelling complex controls cell proliferation and fate determination by regulating chromatin accessibility and programs of gene expression, DNA damage response, replication, splicing, translation, and cell plast…
preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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Although strict maternal transmission of mitochondria is a general feature of animals for ensuring homogeneity in mitochondrial DNA (mtDNA) across generations, exceptions were reported in the recent past. For example, some extremely rare but spectacular cases …
preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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Ochratoxin-A (OTA) is a ubiquitous mycotoxin contaminant in food products and a known nephrotoxin. OTA is hypothesized to be a potential environmental agent causing chronic kidney disease of unknown etiology (CKDu), however the mechanism of OTA toxicity in the…
pubmed
Mahadeo A, Bammler TK, MacDonald J, Zheng AR 等
2025
置信度 0.82
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preprints
2025
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preprints
2025
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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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Non-long terminal repeat retrotransposons (nLTRs), including long and short interspersed nuclear elements (L1 and SINEs), are the most abundant and active mobile elements in mammals. NLTRs play critical mutagenic and regulatory roles during oncogenesis in huma…
pubmed
Fard VN, Tollis M
2025
置信度 0.82
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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ABSTRACT DEAD-box RNA helicases remodel RNA structures in many cellular pathways, yet how their activity is spatially controlled in cells remains poorly understood. The Drosophila germline helicase Vasa functions in ovaries only when localized to cytoplasmic g…
preprints
2026
置信度 0.74
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2025
置信度 0.74
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2025
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2025
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2025
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2026
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2026
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2026
置信度 0.74
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preprints
2025
置信度 0.74
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Endogenous viruses and retroelements occupy a large fraction of genomes, but the properties of proteins they encode remain largely uncharted. Here, we define Atlas viruses, a new clade of endogenous viruses in nematodes with a retrovirus-like genome organizati…
preprints
2026
置信度 0.74
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2025
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2026
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preprints
2024
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2025
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2025
置信度 0.74
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2025
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2025
置信度 0.74
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2025
置信度 0.74
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preprints
2025
置信度 0.74
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During cancer development, mutations promote gene expression changes that cause transformation. Leukemia is frequently associated with aberrant HOXA expression driven by translocations in nucleoporin genes or KMT2A , and mutations in NPM1 . How disparate mutat…
pubmed
Datar GK, Khabusheva E, Anand A, Beale J 等
2025
置信度 0.82
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preprints
2025
置信度 0.74
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The anchor-away (AA) technique enables rapid depletion of nuclear proteins by tethering them to cytoplasmic anchors through rapamycin-induced heterodimerisation. Albeit powerful, in Saccharomyces cerevisiae, this system is restricted to rapamycin-resistant str…
preprints
2025
置信度 0.74
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2025
置信度 0.74
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preprints
2024
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