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• Retraction Note: TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway.
  europepmc 2026 置信度 0.80
• New insights into the Oklo natural fission reactors elucidated from isotopic studies using state-of-the-art analytical techniques.
  europepmc 2026 置信度 0.80
• Emodin Ameliorates Diabetic Cardiomyopathy by Regulating Mitochondrial Dynamics of Fission and Fusion and Ferroptosis through the AHR-Nrf2 Pathway
  europepmc 2026 置信度 0.80
• Attenuated lamin A-prohibitin2 interaction leads to mitochondrial dysfunction in LMNA 289 A>G-mediated dilated cardiomyopathy.
  europepmc 2026 置信度 0.80
• Establishing MS2-MCP-based single-molecule RNA visualization in <i>Schizosaccharomyces pombe</i>
  europepmc 2026 置信度 0.80
• Blue Light Induces Retinal Ganglion Cell Damage by Stimulating Drp1-Dependent Mitochondrial Fission and Activating NF-κB/NOX4 Axis.
  europepmc 2026 置信度 0.80
• Nucleophagy is promoted by two autophagy receptors and inhibited by chromatin-nuclear envelope tethering in fission yeast.
  europepmc 2026 置信度 0.80
• Mitochondrial fission process 1 is required for bovine oocyte maturation through regulation of mitochondrial function and dynamics.
  Oocyte maturation is a complex process that is regulated by a variety of factors. Mitochondria are a key factor affecting oocyte maturation in vitro. Mitochondrial fission process 1 (MTFP1) is located on the inner mitochondrial membrane and mediates the fissio…
  pubmed Han T, Zhao Y, Sun Z, Jiao A 等 2026 置信度 0.82
• Speciation of cesium cation in natural seawater.
  europepmc 2026 置信度 0.80
• Cyclic tensile loading regulates nucleus pulposus cell autophagy through mitochondrial dynamics: molecular mechanisms and implications.
  europepmc 2026 置信度 0.80
• Melatonin postconditioning attenuates myocardial ischemia/reperfusion injury by activating YAP to decrease DRP1-mediated mitochondrial fission.
  europepmc 2026 置信度 0.80
• Thermosensitivity of cellular translation restricts the growth of fission yeast at high temperatures.
  europepmc 2026 置信度 0.80
• Mitochondrial homeostasis imbalance-triggered PANoptosis in traumatic brain and spinal cord injury: from mechanism to therapeutic strategies.
  europepmc 2026 置信度 0.80
• IPPNW in Hiroshima: a call to end 'the curse of nuclear fission'.
  europepmc 2013 置信度 0.80
• Actin dynamics during contractile ring assembly drives mitotic nuclear displacement in fission yeast.
  europepmc 2026 置信度 0.80
• Variecolactone, a Natural PDE4 Inhibitor from Marine-Derived &lt;i&gt;Talaromyces&lt;/i&gt; sp. ZSD-1, Alleviates Amyloid-β Accumulation and mtDNA Dyshomeostasis via cAMP-PKA-CREB Signaling Pathway.
  europepmc 2026 置信度 0.80
• The SDF-1α/CXCR4 axis regulates chondrocyte mitochondrial dynamics via the ERK/AMPKα pathway.
  europepmc 2026 置信度 0.80
• Exploring mitochondrial functions and dysfunctions in chondrocytes: toward the identification of novel therapies for osteoarthritis.
  europepmc 2026 置信度 0.80
• Meiotic cohesin Rec8 imposes fitness costs on fission yeast gametes favoring the evolution of parental bias in gene expression
  europepmc 2026 置信度 0.80
• Regulation of mitochondrial biogenesis and energy metabolism in the heart.
  europepmc 2026 置信度 0.80
• Targeting mitochondrial quality control in diabetic kidney disease: emerging therapeutic opportunities.
  europepmc 2026 置信度 0.80
• Fumarate inhibits the formation of neutrophil extracellular traps (NETs) in a Nrf2-controlled and Annexin-A1-dependent manner associated with mitochondrial fusion.
  Neutrophil extracellular traps (NETs) constitute a critical antimicrobial mechanism, yet excessive or dysregulated NET release contributes to endothelial injury and tissue damage. Therefore, identifying physiological and pharmacological regulators of NET forma…
  pubmed Burczyk G, Kolaczkowska E 2026 置信度 0.82
• Functional polysaccharide-based biosorbents as efficient green alternatives for radionuclide removal from radioactive waste: a review.
  Radioactive waste presents persistent environmental and health challenges, creating an urgent need for remediation materials that are not only effective and selective but also sustainable. Conventional treatment methods often suffer from high cost, limited sel…
  pubmed Ghobashy MM, Sharef HY, Baata M, Almoiqli MS 等 2026 Aug 3 置信度 0.82
• Maximizing nuclear capture and fission reactions: The innovative potential of boron delivery agents for neutron capture therapy in cancer treatment.
  Neutron capture therapy (NCT) is a binary radiotherapeutic modality that relies on the nuclear capture and fission reactions of boron-10 for the selective destruction of cancer cells. Boron delivery agents (BDAs) are used to selectively deliver boron-10 to can…
  pubmed Abd-Elghany AA, Hassan AI, Yousef AMM, Diab HM 等 2026 Jul 28 置信度 0.82
• Dual spectroscopy technique for vapor-phase chlorides and iodine detection in nuclear systems.
  The need for efficient, real-time monitoring of vapor-phase fission products in nuclear systems is critical for advancing nuclear technologies. This study explores a dual-spectroscopy technique, combining ultraviolet-visible (UV-vis) absorbance and laser-induc…
  pubmed Austin R, LeCroy G, Gakhar R, Roper R 等 2026 Jul 29 置信度 0.82
• Mitophagy Inhibition Promotes Survival and Mitochondrial Function in MYC-driven HCC.
  Hepatocellular carcinomas (HCC) are genetically heterogeneous cancers frequently characterized by MYC gene amplification or hyperactivating &#x3b2;-catenin ( CTNNB1 ) mutations. Analysis of TCGA transcriptomics revealed that MYC-driven HCC tumors have decrease…
  pubmed Lesner NP, Kim LC, Shelton SD, Landis M 等 2026 Jul 14 置信度 0.82
• Fieldable Microfluidic Platform for Separation and Assay of U and Pu from Fission Samples in Environmental Matrices.
  An integrated microfluidic platform has been designed for in-field separation and assay of Pu and U from environmental samples. Separation of Pu and U from the sample matrix is accomplished by performing two sequential liquid-liquid extractions using 3D-printe…
  pubmed Glennon KJ, Valdovinos HF, Bence JA, Parsons-Davis T 等 2026 Jul 15 置信度 0.82
• Sensitivity Analysis of Cracking Behavior in Fully Ceramic Microencapsulated Fuel.
  To identify the key factors influencing the cracking behavior of fully ceramic microencapsulated (FCM) fuel, this study employed the MOOSE V1.3 multiphysics coupling platform and the cohesive phase-field fracture theory to simulate crack initiation and propaga…
  pubmed Liu S, Huang H, Chen C, Zhao Y 等 2026 Jul 8 置信度 0.82
• Molecular mechanism of CtBP1-S/BARS-driven membrane fission and its cellular control by metabolic ligands.
  CtBP1-S/BARS (C-terminal binding protein 1-S/Brefeldin A ADP-Ribosylation Substrate) is a moonlighting protein with key roles in membrane trafficking and gene regulation. We show that CtBP1-S/BARS couples enzymatic lipid remodeling [lysophosphatidic acid (LPA)…
  pubmed De Tito S, Filograna A, Zhukovsky MA, Monte ML 等 2026 Jul 24 置信度 0.82
• Determination of the half-Life of (147)Nd and absolute gamma-ray emission intensities from the excited states of (147)Pm.
  The activity of fission products is an important indicator of the neutron flux yield from nuclear fission. Neodymium-147 is one such product and is of importance in nuclear forensics due to its unique decay characteristics. Literature for the half-life and abs…
  pubmed Collins SM, Russell B, Ivanov P, Mohamud H 等 2026 Jul 21 置信度 0.82
• Ruthenium in the nuclear fuel cycle and the environment: Behavior, release, and hazard relevance.
  Ruthenium isotopes constitute a distinctive class of fission products whose radiological relevance is governed less by their inventory than by chemical speciation and release conditions. Under normal reactor operation, ruthenium is largely retained in metallic…
  pubmed Zuba I, Pawlukojc A, Distler P, John J 2026 Jul 17 置信度 0.82
• On-Line Monitoring of Solvent Extraction Streams by Laser-Induced Breakdown and Raman Spectroscopy.
  Efficient monitoring of solvent extraction processes is essential for the safe and sustainable operation of nuclear fuel reprocessing, particularly under conditions where radiolysis and solvent degradation can affect separation efficiency and phase stability. …
  pubmed Budylin GS, Petrov VA, Shirshin EA, Tarazanova MA 等 2026 Jul 20 置信度 0.82
• Singlet Fission Dynamics Controlled by an Electronic Crossing Seam.
  Electronic degeneracies and near-degeneracies including conical intersections and avoided crossings, typically accompanied by strong vibronic couplings and nonadiabatic transitions, play fundamental roles in photochemical, photophysical, and photobiological pr…
  pubmed Liu R, Zhu X, Gu B 2026 Jul 30 置信度 0.82
• Metabolic reprogramming in Alzheimer's disease: Interaction between receptor tyrosine kinase signaling, noncoding RNAs, and Neuron-Glia energy networks.
  Alzheimer's disease (AD) is increasingly understood as a disorder involving impaired brain energy metabolism rather than being solely caused by amyloid and tau pathology. This chapter offers a comprehensive overview of how glucose hypometabolism, mitochondrial…
  pubmed Karmakar A, Roycowdhury P, Sengupta P, Mukhopadhyay D 2026 置信度 0.82
• Mommy Issues: How Maternal Diet Shapes Offspring Mitochondrial Physiology.
  Exposure to early life stressors, including maternal obesity and the consumption of a calorically dense diet, during critical windows of fetal development is associated with an elevated and earlier risk of developing childhood obesity, type 2 diabetes, and oth…
  pubmed Gomez-Sharma A, McCurdy CE 2026 Jul 10 置信度 0.82
• Neutron dose assessment by unfolding spectra from neutron activation analysis of a smartphone.
  Smartphones are widely available and can serve as opportunistic dosimeters in nuclear emergencies. However, the complex internal structures of smartphones lead to neutron moderation, scattering, absorption and gamma-ray self-absorption. These effects may induc…
  pubmed Hu B, Xu X, Sun T, Yue J 等 2026 Jul 21 置信度 0.82
• Intrinsic Generation of Angular Momenta and Entanglement in Fission.
  Nuclear time-dependent density functional theory is used to investigate spin generation and entanglement of fission fragments in spontaneous fission of ^{252}Cf, incorporating both axial and nonaxial deformations. Axially symmetric fission trajectories enforce…
  pubmed Li B, Zhang DD, Vretenar D, Nikšić T 等 2026 Jun 26 置信度 0.82
• Speciation of cesium cation in natural seawater.
  Cesium radioactive isotopes ( 134 Cs and 137 Cs) are key fission products released during nuclear accidents such as Fukushima and through routine operations of nuclear power plants. This study presents a combined experimental and computational investigation of…
  pubmed Plasajec A, Beccia MR, Jeanson A, Siberchicot B 等 2026 Jul 28 置信度 0.82
• Simulation and experimental validation of spent nuclear fuel cask shields.
  This study presents a combined computational-experimental approach to the design of radiation shields for a metallic Dual-Purpose Casks (DPC) intended for the transport and interim storage of spent fuel. The shield performance was simulated using ORIGEN 2.1 an…
  pubmed Kiani MA, Outokesh M, Ahmadi SJ, Rezaeian M 等 2026 Jul 9 置信度 0.82
• Establishing MS2-MCP-based single-molecule RNA visualization in Schizosaccharomyces pombe.
  Single-molecule RNA imaging using the MS2-MCP system has transformed the study of RNA biology across model organisms. However, this technology has remained unavailable for fission yeast (Schizosaccharomyces pombe) even though fission yeast is a central model f…
  pubmed Weidemann DE, Turner SC, Chethan SG, Hauf S 2026 Jul 1 置信度 0.82
• Impact of Boric Acid on the Stability of Hydrogen Peroxide in Aqueous Solution.
  The reactivity of H 2 O 2 is of importance for its role as an oxidant in many processes. It is an important oxidant produced radiolytically in nuclear reactors, and knowing its stability is of key importance when predicting corrosion of fuel cladding and struc…
  pubmed Petersson F, Longo V, Jonsson M 2026 Jun 30 置信度 0.82
• Statin-Induced Coenzyme Q Deficiency Induces Metabolic Reprogramming in Astrocytes.
  Statins are commonly used cholesterol-lowering drugs, but their effects on astrocyte oxidative metabolism are poorly understood. To investigate this, rat astrocytes were exposed to 200 nM atorvastatin or simvastatin for 6 days and then assessed for changes in …
  pubmed Wojcicki K, Galganski L, Budzinska A, Figura G 等 2026 Jun 7 置信度 0.82
• The history and perspective on quality factors proposed by the International Commission on Radiological Protection (ICRP).
  Proper consideration of the relative biological effectiveness (RBE) is essential for evaluating potential health risks associated with exposure to cosmic radiations spanning a broad range of linear energy transfer (LET). The quality factor as a function of LET…
  pubmed Sato T 2026 Jul 置信度 0.82
• Dark side of glial talk: Role of neuroinflammation in neurodegeneration.
  Communication between astrocytes and microglia establishes a basis for maintaining cellular homeostasis, metabolic processes, and injury response in the central nervous system. Activation of astrocytes and microglia is a major initial phase of the response of …
  pubmed Okhalnikov AD, Savchenko R, Schelchkova NA, Varochkina MA 等 2026 Jun 20 置信度 0.82
• Technetium-99 determination in low-volume samples from the global environment with accelerator mass spectrometry.
  The long-lived fission product technetium-99 ( 99 Tc, t 1/2 = (2.111 &#xb1; 0.012) &#xd7; 10 5 years) was successfully detected in small-volume (10 L, and 1 g, respectively) environmental samples such as Pacific Ocean and river water, Antarctic snow, and peat.…
  pubmed Hain K, Adler S, Faestermann T, Fifield LK 等 2026 Jun 5 置信度 0.82
• Framework materials for nuclear waste treatment.
  Driven by energy demand and environmental safety, the ability to treat and dispose of nuclear waste is sought to fulfil the demand for sustainable nuclear power. Radioactive byproducts generated by nuclear fission, including cationic radionuclides ( 235 UO 2 2…
  pubmed Hao M, Liu X, Xie Y, Chen H 等 2026 Jul 6 置信度 0.82
• Quantum sensing with triplet pair states: A theoretical study.
  Molecular quantum sensors represent a promising frontier for the detection of nuclear magnetic resonance signals and alternating current magnetic fields at the nanoscale, potentially reaching single-proton sensitivity. Although the triplet states T&#x302; of m…
  pubmed Concilio MG, Wang Y, Wang S, Kong X 2026 Jun 21 置信度 0.82
• Potential targets for boron transport in boron neutron capture therapy.
  Boron Neutron Capture Therapy (BNCT) is a binary cancer therapy that involves boron ( 10 B) drug administration and epithermal/thermal neutron irradiation. The nuclear fission reaction between low-energy thermal neutrons and 10 B atoms accumulated in cancer ce…
  pubmed Wei Y, Zhu W, Chen Q, Alnufaei H 等 2026 置信度 0.82
• Mitochondria-targeted photodynamic nanoparticles boost antitumor immunity by suppressing mitophagy in osteosarcoma.
  Osteosarcoma (OS) responds poorly to immunotherapy owing to its highly immunosuppressive phenotype. Photodynamic therapy (PDT) can induce mitochondrial damage by generating reactive oxygen species (ROS), thereby triggering immunogenic cell death (ICD) and acti…
  pubmed Deng Q, Li J, Tong Z, Zhang L 等 2026 Nov 置信度 0.82
• Measurements of the relative gamma-ray emission intensities from the decay of (127)Sb and (126)Sb.
  The radionuclides 127 Sb and 126 Sb are of interest in the fields of nuclear forensics and nuclear reactor design. Given the discrepancies observed between previous measurements and evaluated data, measurements of their gamma-ray emission intensities relative …
  pubmed Liang J, Chen G, Zhang X, Guan Q 等 2026 Oct 置信度 0.82
• The Role of MicroRNAs Carried by Extracellular Vesicles in Tumorigenesis Through Reprogramming the Mitochondrial Information Processing System.
  Mitochondrial dysfunction is not merely a byproduct of transformation but a driver of tumorigenesis, metastasis, and therapeutic resistance. Recent advancements in intercellular communication have identified Extracellular Vesicles (EVs) or exosomes as critical…
  pubmed Ghosh-Mitra A, Patel M, Das S 2026 Jun 5 置信度 0.82
• Redox Imbalance in Gestational Diabetes Mellitus: Mechanistic Insights, Emerging Biomarkers, and Therapeutic Perspectives.
  Gestational diabetes mellitus (GDM) is increasingly recognized as a complex pathology rooted in systemic and organelle-level dysfunction, specifically involving chronic low-grade inflammation (CLGI), mitochondrial impairment, and endoplasmic reticulum (ER) str…
  pubmed Uthaiah CA, Sahu T, Singh V, Abraham J 2026 May 25 置信度 0.82
• A stand-alone ICln release module revealed by deconstructing the SMN complex with engineered Brr1.
  The assembly of the Sm core, a ring-shaped protein complex essential for spliceosomal small nuclear ribonucleoprotein particle biogenesis, is chaperoned by the SMN complex in most eukaryotes. Intriguingly, the budding yeast Saccharomyces cerevisiae possesses a…
  pubmed Hu Y, Zhang J, Xu B, Wang Y 等 2026 Jun 8 置信度 0.82
• GPATCH11 ortholog Sap34 regulates pre-mRNA splicing by interacting with early spliceosomal complexes in Schizosaccharomyces pombe.
  Pre-mRNA splicing is an essential step in gene expression regulation. It is mediated by the spliceosome, a large ribonucleoprotein complex that undergoes dynamic structural and compositional rearrangements during each splicing cycle. Although the mechanisms of…
  pubmed Cipakova I, Karika LO, Hronska L, Selicky T 等 2026 Jun 8 置信度 0.82
• Hyperoside protects against poly-GR-mediated neurodegeneration via regulation of mitochondrial fission and oxidative stress in C9orf72-associated ALS.
  Arginine-rich poly-glycine-arginine (poly-GR), a toxic dipeptide repeat protein generated from C9orf72 hexanucleotide repeat expansion, drives mitochondrial dysfunction, oxidative stress, and neuronal loss in amyotrophic lateral sclerosis (ALS). Hyperoside, a …
  pubmed Hsieh WC, Lin CY, Wu HC, Weng EF 等 2026 Jun 4 置信度 0.82
• Nuclear ground-state properties of Z=122 superheavy nuclei.
  A systematic investigation of the nuclear structure and decay properties of $Z=122$ superheavy nuclei in the range of $160\leq N \leq 200$ is carried out within the framework of the self-consistent Hartree-Fock-Bogoliubov approach, based on a Skyrme energy den…
  pubmed Ouhachi M, Oudih MR 2026 Jun 3 置信度 0.82
• Multiple ammonium transporters in fission yeast are coordinated by transcriptional and localization regulation in response to nitrogen starvation.
  Ammonium is the preferred nitrogen source for microorganisms. We investigated the regulation of ammonium transporters Amt1, Amt2 and Amt3 in the fission yeast Schizosaccharomyces pombe. Expression of the amt1+ gene increases under nitrogen starvation as well a…
  pubmed Nakase Y, Ng SL, Tan ACW, Shibatani A 等 2026 Jul 1 置信度 0.82
• Preparation and accurate quantification of uranium coatings on thin backings for high-flux neutron detectors.
  Dense and uniform uranium coatings are fabricated on 2&#x202f;&#x3bc;m-thick aluminized mylar foil via electrodeposition for high-flux neutron detection. The thin mylar backing is selected for its ductility and low neutron-interaction cross-section to minimize…
  pubmed He Y, Liu Y, Liu Y, Chen K 等 2026 Sep 置信度 0.82
• The role of cell growth rate on accumulation of the mitotic cyclin Cdc13 in fission yeast.
  Eukaryotic cells control their size by coordinating growth and division. Fission yeast divide at a reproducible cell size due to regulated activation of the cyclin-dependent kinase Cdk1. The nuclear concentration of mitotic cyclin Cdc13 increases in a time-dep…
  pubmed Vandal SE, Rezaee S, Nieto C, Flynn MJ 等 2026 May 15 置信度 0.82
• Canavanine-based assay for gross chromosomal rearrangements reveals genome instability hotspots and modulating genes in fission yeast.
  Gross chromosomal rearrangements are a hallmark of many diseases and cancers. The study of their biogenesis and the mechanisms underlying their formation is greatly facilitated by the availability of genetic reporter assays in model organisms. We present here …
  pubmed Ait Saada A, Ollivier C, Costa AB, Moreau K 等 2026 May 16 置信度 0.82
• MTFR2 regulated the proliferation, apoptosis, migration, and invasion of endometrial cancer cells through the Drp1/MFN1 signaling pathway mediated mitochondrial fission.
  Mitochondrial dynamics play a critical role in tumor progression, yet the contribution of mitochondrial fission regulator 2 (MTFR2) to endometrial cancer (EC) remains poorly defined. This study investigated the clinical relevance and functional role of MTFR2 i…
  pubmed Bai X, Wei M, Wang Q, Yang Y 2026 Apr 30 置信度 0.82
• Radiological safety assessment of gamma spectroscopy based spent fuel burnup analysis at the ITU TRIGA Mark II reactor.
  This study investigates radiological safety and photon attenuation behavior during spent fuel inspection and burnup analysis at the ITU TRIGA Mark II Research Reactor. A lead-shielded fuel inspection system equipped with an HPGe detector was used to perform re…
  pubmed Akyurek T, Boduroglu Z, Kaya A, Erbay O 等 2026 Sep 置信度 0.82
• Blue Light Induces Retinal Ganglion Cell Damage by Stimulating Drp1-Dependent Mitochondrial Fission and Activating NF-κB/NOX4 Axis.
  This study aimed to investigate the mechanisms of blue light-induced neurotoxicity in retinal ganglion cells (RGCs), focusing on the roles of mitochondrial dynamics and oxidative stress.
  pubmed Han XH, Wang T, Sun GF, Xie X 等 2026 May 1 置信度 0.82
• FERPIR promotes cardiomyocyte survival and attenuates cardiac remodeling after myocardial infarction.
  PIWI-interacting RNAs (piRNAs) are widely expressed in cardiac tissues and play important roles in cardiac pathophysiology. However, their functions and molecular mechanisms in cardiac remodeling following myocardial infarction (MI) and cardiomyocyte ferroptos…
  pubmed Wang R, Chen X, Ren J, Hu S 等 2026 May 21 置信度 0.82
• Inhibition of the oncogenic GTPase dynamin-related protein 1 (DRP1) by the FDA-approved drug fosaprepitant: In silico, biophysical, and in vitro characterization of its anti-myeloma activity.
  Mitochondrial fission plays a crucial role in sustaining cellular homeostasis, and disturbances in this process have been linked to numerous pathological conditions, including cancer. The central regulator of mitochondrial division is the large GTPase dynamin-…
  pubmed Marchese E, Murfone P, Valentino I, Cantafio MEG 等 2026 Jun 置信度 0.82
• Local polarity modulation in triangular pores of covalent organic frameworks for iodine capture from water.
  Radioactive iodine from nuclear fission processes can enter water systems in various ways, adversely affecting human health and the environment. Herein, we construct a series of covalent organic frameworks (COFs) with triangular pores and different local polar…
  pubmed Hao M, Wu Y, Zhang J, Liu X 等 2026 May 20 置信度 0.82
• Ruthenium Speciation during Acidification of Alkaline Solution.
  Ruthenium (Ru) has applications in nuclear medicine and is also a highly radioactive and volatile fission product. Due to its volatility in oxidizing environments, alkaline gas traps are used to capture its vapors. However, analyzing these solutions using indu…
  pubmed Leblanc M, Baghdadi S, Martin PM, Prieur D 等 2026 May 12 置信度 0.82
• Realizing irradiation-resistant metallic alloys by immobilizing induced defects.
  Materials capable of withstanding extreme conditions are essential for advanced fission and fusion technologies. The development of irradiation-tolerant structural materials hinges on the suppression of defect evolution that could lead to mechanical degradatio…
  pubmed Huang S, Su Z, Ma S, Xu B 等 2026 May 15 置信度 0.82
• m(6)A-Mediated epitranscriptomic control of mitochondrial dysfunction in neurodegeneration.
  Mitochondrial dysfunction is a common pathology of neurodegenerative diseases, which contributes to neuronal vulnerability via excessive oxidative stress, impaired bioenergetics, and dysregulated apoptosis. Emerging studies highlighted the critical role of epi…
  pubmed Jauhari A 2026 Sep 置信度 0.82
• KEAP1-mediated mitochondrial remodeling on stiffness-graded collagen substrates drives hepatocellular carcinoma adaptation.
  Mechanical and structural cues of the extracellular matrix (ECM) regulate tumor cell metabolism and drug response, yet the molecular mediators that link these biophysical signals are unclear. We present an elastically supported surface platform bioengineered w…
  pubmed Elblová P, Calé A, Andělová H, Morán L 等 2026 Nov 置信度 0.82
• Hydrostatic Pressure as a Sensing and Control Parameter for Fission-Nuclear Process.
  This study proposes a novel physical effect arising in radioactive matter: initiation and control of a nuclear chain reaction through high hydrostatic pressure. We present the design of a compression-assisted reactor consisting of a titanium chamber with a cyl…
  pubmed Lozanova S, Ivanov A, Roumenin C 2026 Apr 23 置信度 0.82
• Identification of METTL3 and PRMT5 as an oncogenic pair for the prognosis and therapeutic targets of colorectal cancer subtype.
  METTL3 is a pivotal N6-methyladenosine (m&#x2076;A) regulator that is linked to a worse prognosis of colorectal cancer (CRC). However, METTL3's oncogenic molecular networks in CRC remain unclear. This study aims to establish a co-expression network of METTL3 a…
  pubmed Zhao Q, Li S, Chen A, Zhu S 等 2026 May 12 置信度 0.82
• A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis.
  Meiosis is a conserved yet evolutionarily varied process underpinning sexual reproduction in eukaryotes. In the malaria parasite Plasmodium, meiosis is unconventional: it occurs immediately after fertilisation (post-zygotic) and must be coordinated with the tr…
  pubmed Yanase R, Hair M, Zeeshan M, Ferguson DJP 等 2026 May 12 置信度 0.82
• MitoTEMPO modulates trigeminal activation and mitochondrial biogenesis in a nitroglycerin-induced migraine model.
  Migraine is a disabling neurovascular disorder in which neuroinflammation, trigeminal activation, and mitochondrial dysfunction play central roles. Mitochondria-targeted antioxidants such as mitoTEMPO may modulate these mechanisms; however, their effects in ni…
  pubmed Savran OY, Alcan-Kirtas S, Atalay O, Kilic HB 等 2026 May 11 置信度 0.82
• Thermodynamics and Phase Stability of SmF(3) with LiF, NaF, and KF for Molten Salt Reactor Applications.
  Understanding and controlling the thermodynamic behavior of molten fluoride salts is critical for their deployment in advanced energy systems, including molten salt reactors. Self-consistent Gibbs energy functions were developed to describe the thermochemical …
  pubmed Wilson JA, Baker EL, Eaton LM, Husek A 等 2026 May 5 置信度 0.82
• (99)Mo production cycle based on muon nuclear-capture reaction with infinite (99)Tc resources.
  The paper proposes a novel 99 Mo production cycle based on a 99 Tc (&#x3bc; - , &#x3bd;) 99 Mo reaction (Measday, 2001; Petitjen et al., 1971; Backenstoss et al., 1971; Measday et al., 2007; Niikura et al., 2024; Yamaguchi et al., 2025; Mizuno et al., 2025), u…
  pubmed Matsuzaki T, Sakurai H 2026 Sep 置信度 0.82
• Physalin A Restores Redox and Mitochondrial Homeostasis to Protect against Diabetic Retinopathy.
  To determine whether physalin A (PA) safeguards the outer blood-retinal barrier under diabetic stress by engaging nuclear factor erythroid 2-related factor 2 (Nrf2) to restore redox balance and restrain ferroptosis in human retinal pigment epithelial (hRPE) ce…
  pubmed Xiao YR, Hsieh YW, Lin WY, Hsieh YS 等 2026 Jul 置信度 0.82
• VPS13B maintains lysosomal homeostasis through regulation of TFEB.
  Cohen syndrome (CS) is a rare autosomal recessive neurodevelopmental disorder characterized by intellectual disability, microcephaly, retinal dystrophy, and neutropenia. We previously demonstrated that VPS13B mediates phosphatidylinositol 4-phosphate (PI4P) tr…
  pubmed Lee SK, Park S, Yeom MY, Lee JA 2026 May 8 置信度 0.82
• Gaseous radioactive wastes treatment system of GAMA-AHR.
  GAMA-AHR is an aqueous homogeneous reactor designed to produce 2000 six-day Ci per week of 99 Mo with 200 kWth thermal power. During its operation, GAMA-AHR produces fission product gases, predominantly xenon and radiolytic gas. Radiolytic gas is dominated by …
  pubmed Kusnanto, Harto AW, Afifah NA, Adi Putra MY 2026 Aug 置信度 0.82
• Drp1 regulates mitochondrial health and controls skeletal muscle mass through the Erk1/2-Nur77 pathway.
  The maintenance of skeletal muscle mass relies on mitochondrial quality control, including balanced dynamics and mitophagy. Dynamin-related protein 1 (Drp1), a central mediator of mitochondrial fission, is essential for these processes, yet its role in muscle …
  pubmed Ma AM, Tran PH, Yang NL, Ngo J 等 2026 May 8 置信度 0.82
• The protective effects of selenium on mitochondrial quality under exogenous and endogenous stressors.
  Selenium (Se) and selenoproteins play a significant role in preventing mitochondrial damage. Se regulates mitochondrial dynamics, biogenesis, and mitophagy, but the mechanisms by which it controls mitochondrial quality remain to be fully characterized. Thus, t…
  pubmed Skalny AV, Aschner M, Santamaria A, Barbosa F Jr 等 2026 Jul 25 置信度 0.82
• Time-Space-Medium Collaboratively Modulated LIBS Combined with Matrix Dilution: From Self-Absorption to Isotope Discrimination of Lithium.
  In response to the urgent need to address global climate change and achieve deep decarbonization of energy systems, clean energy technologies are undergoing transformative advancement. Within this context, a remote, in situ, and rapid technology for high-preci…
  pubmed Lai Z, Wu S, Xu C, Zhang Z 等 2026 May 20 置信度 0.82
• Modeling fission product nucleation in molten NaCl using universal machine-learning potentials.
  The design of molten salt nuclear reactors (MSRs) requires a detailed understanding of the formation, precipitation, and transport of solid fission products in the fuel salt. However, the experimental characterization of these processes remains challenging and…
  pubmed Salcedo A, Pireddu G, Salanne M, Lambertin D 2026 Jun 3 置信度 0.82
• Lycopene Attenuates Hexavalent Chromium-Induced Kidney Injury By Modulating PINK1/Parkin-Mediated Mitophagy.
  Hexavalent chromium [Cr(VI)] is a well-established environmental nephrotoxicant that induces renal injury. Lycopene (LYC), one of the most potent naturally occurring antioxidants found in plants, has demonstrated protective effects against various forms of oxi…
  pubmed Zhang QM, Zhang X, Xia LB, Ge K 等 2026 Sep 置信度 0.82
• CircMIRLET7BHG facilitates mast cell degranulation to accelerate allergic rhinitis progression by enhancing IL-33 mRNA stability via interacting with polypyrimidine tract-binding protein 1.
  Mast cell (MC) degranulation is associated with allergic rhinitis (AR) progression. Although circMIRLET7BHG has been identified as a promoter of AR development, its potential regulatory role in MC degranulation during AR progression has not been clarified.
  pubmed Zhan J, Li R, Liang Y, Luo D 等 2026 Aug 1 置信度 0.82
• Sphericity Control of UO(2) Fuel Kernels Through Gelling Media Coupling with Multi-Field Washing.
  Nuclear energy has emerged as a crucial technological solution for ensuring energy security and achieving carbon neutrality goals, given its ultra-high energy density and near-zero carbon emissions against the backdrop of rapid socioeconomic development, incre…
  pubmed Geng L, Jing H, Zhao Y, Li J 等 2026 Apr 8 置信度 0.82
• Ligilactobacillus salivarius 8-2 attenuates intestinal mucosal injury in chicks via the mitochondrial fision-glycometabolism reprogramming axis.
  The intestinal mucosa is crucial for nutrient absorption and barrier function. In this study, a newly identified strain of Ligilactobacillus salivarius (L. sa. 8-2) exhibited a mucosal protective effect in chick intestinal injury models. However, the underlyin…
  pubmed Hua Y, Zou M, Zhang L, Chen L 等 2026 Jul 置信度 0.82
• Dynamin 2 Regulates Mitochondrial Mitotic Fission in Pulmonary Hypertension.
  DRP1 (dynamin-related protein 1) mediates mitochondrial fission and permits rapid cell cycle progression in hyperproliferative cells by coordinating nuclear and mitochondrial division, a process called mitotic fission. However, DRP1 alone appears insufficient …
  pubmed Dasgupta A, Chen KH, Wu D, Yerramilli VS 等 2026 May 22 置信度 0.82
• m6A-Mediated epitranscriptional reprogramming drives cardiac fibrosis by suppressing PGC-1α and boosting mitochondrial fission.
  BACKGROUND: Dysregulated mitochondrial fission drives pathological cell states in cardiac fibrosis, but its upstream regulatory mechanisms remain poorly understood. The role of epitranscriptomic regulation, particularly N6-methyladenosine (m6A) modification, i…
  pubmed Cao XY, Tu B, Cao ZR, Liu F 等 2026 Apr 24 置信度 0.82
• Crown Ether-Incorporated Metal Halides Unify High-Performance Iodine Capture with Built-In Optical Monitoring of Adsorption Process.
  The management of radioactive iodine, a typical fission product released in the nuclear fuel cycle and nuclear accidents, demands not only a deep decontamination capability but also reliable monitoring of adsorbent status. However, this critical need is yet un…
  pubmed Lin Z, Wang MC, Peng F, Li JJ 等 2026 May 6 置信度 0.82
• Chromosome fusion enhances dependency on Rif1 for entanglement resolution during meiosis in S. pombe.
  Chromosome fusion represents a major form of karyotype evolution. However, it remains unclear how cells adapt to drastic changes in chromosomal organisation and overcome the topological challenges imposed by fusion to ensure accurate segregation, genome stabil…
  pubmed Zhou Y, Wei X, Zhang J, Gu X 等 2026 Apr 22 置信度 0.82
• p-Sulfonatocalixarene-Based Complexation Mitigates Hepatorenal Toxicity of Anticancer Alkaloids without Loss of Efficacy: A Strategy for Selective Detoxification.
  p-Sulfonatocalix[n]arenes (SCnA, where n&#x2009;=&#x2009;6, 8) have emerged as promising supramolecular hosts for encapsulating active pharmaceutical ingredients (APIs) through host-guest complexation, enhancing solubility, stability, and bioavailability. In t…
  pubmed Tan L, Jing Z, Yu X, Liu Y 等 2026 Apr 20 置信度 0.82
• Telomere-to-telomere assemblies of Paracoccidioides genomes.
  Paracoccidioides is a genus of dimorphic fungal pathogens endemic to Latin America. We generated long-read de novo assemblies for 11 isolates representing 4 species of the brasiliensis complex (Paracoccidioides brasiliensis, Paracoccidioides americana, Paracoc…
  pubmed Grinevich D, Kompathoum O, Li J, Turissini DA 等 2026 Jun 3 置信度 0.82
• Mitochondrial redox homeostasis links organellar stress surveillance to germline and somatic integrity in Caenorhabditis elegans.
  Mitochondrial redox homeostasis is essential for cellular metabolism and organismal development. To investigate the consequences of disrupting redox homeostasis in this organelle in a metazoan organism, we generated a double mutant lacking mitochondrial glutat…
  pubmed Valenzuela-Villatoro M, de la Cruz-Ruiz P, Guerrero-Gómez D, Gómez-Orte E 等 2026 Jun 置信度 0.82
• Radiation interaction and attenuation behaviour of selected MAX phases: Insights into neutron, gamma-ray, and charged particle shielding.
  In the present investigations, the authors have used EpiXs, NGCal, and InChaP software to assess the shielding parameters for gamma-ray, neutron, and charged particles in specific MAX phase materials such as Ti 2 AlC, Ti 2 AlN, V 2 AlC, Cr 2 AlC, Nb 2 AlC, Ta …
  pubmed Hiremath GB, Singh VP, Ayachit NH, Badiger NM 2026 Jul 置信度 0.82
• Fumarate inhibits the formation of neutrophil extracellular traps (NETs) in a Nrf2-controlled and Annexin-A1-dependent manner associated with mitochondrial fusion.
  Neutrophil extracellular traps (NETs) constitute a critical antimicrobial mechanism, yet excessive or dysregulated NET release contributes to endothelial injury and tissue damage. Therefore, identifying physiological and pharmacological regulators of NET forma…
  pubmed Burczyk G, Kolaczkowska E 2026 置信度 0.82
• Extracellular vesicle delivery of Myricetin suppresses ovarian cancer through mitochondrial dynamics by downregulating the ECM1/NF-κB/TGFβ signaling pathway.
  Ovarian cancer is classified as a female malignancy commonly known as a silent killer with no early detection symptoms. Extracellular matrix protein 1 (ECM1) is associated with the Epithelial-mesenchymal transition (EMT) and metastasis process in different can…
  pubmed Pande K, Singh SA, Kannan A 2026 Apr 16 置信度 0.82
• Mitochondrial Fission Regulator 1-Like Protein Protects the Heart from Ischemia/Reperfusion Injury via Dual Mitochondrial Mechanisms.
  Mitochondrial dysfunction is pivotal in the pathogenesis of cardiac ischemia/reperfusion (I/R) injury. Restoring mitochondrial function represents a promising strategy for mitigating I/R-induced cardiac injury. Mitochondrial fission regulator 1-like protein (M…
  pubmed Wei M, Song Y, Zhu M, Hu X 等 2026 置信度 0.82
• Nuclear basket subunits Nup211 and Rsm1 influence RNA 3'-processing and transcription termination in fission yeast.
  The fission yeast phosphate acquisition ( PHO ) regulon is repressed under phosphate-replete conditions by upstream lncRNA-mediated transcriptional interference. Inositol-1-pyrophosphates control PHO gene expression via their action as agonists of precocious P…
  pubmed Bednor L, Innokentev A, Sanchez AM, Sem A 等 2026 Jun 16 置信度 0.82
• Novel calcium silicate from fly ash for simulated seawater Sr(2+) decontamination: efficient removal and stable immobilization.
  In this study, a series of calcium silicate adsorbents were prepared using fly ash as the raw material via a dynamic hydrothermal process. These adsorbents were employed to address radioactive contamination caused by 90 Sr, a typical fission product resulting …
  pubmed Liu Y, Guo C, Yao Z, Qin Q 等 2026 Apr 1 置信度 0.82