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Reliable and secure transmission of medical images is essential for telemedicine, remote diagnosis, and distributed healthcare systems. However, medical image communication over heterogeneous networks often suffers from packet loss, channel noise, and privacy …
pubmed
Alsuwat E
2026 May 23
置信度 0.82
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Federated learning (FL) enables multiple devices to collaboratively train a shared model while keeping their data localized, thereby preserving privacy. Despite its promise, FL continues to face key challenges such as model heterogeneity, high communication ov…
pubmed
Salman H, Pradat-Peyre JF, Guehis S, Charara N 等
2026 May 23
置信度 0.82
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Rectal cancer remains a global health burden, with immunotherapy emerging as a transformative treatment modality demonstrating substantial pathological complete response rates across molecular subtypes. However, current response assessment methods based on ana…
pubmed
Wang Q, Chen Y
2026 Oct
置信度 0.82
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Real-world data (RWD) are increasingly recognized as essential for understanding patient populations underrepresented in clinical trials and for supporting data-driven learning in healthcare. For smaller subgroups, the value of RWD depends on standardization a…
pubmed
Ross E, Bouissou O, Helland Å, Faxvaag A
2026 Sep 1
置信度 0.82
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Sharing clinical datasets requires rigorous privacy guarantees to prevent subject re-identification. This paper presents a privacy analysis tool that operates entirely client-side, ensuring data protection by eliminating the need for server-side processing. Th…
pubmed
Gameiro J, Barros V, Almeida JR, Oliveira JL
2026 May 21
置信度 0.82
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We explore how privacy can be made both usable and enforceable within FLAME, a federated learning platform developed in the German PrivateAIM project. We propose a Privacy-Enhancing Technology (PET) Integration Maturity Model with three levels: Analysis-Based,…
pubmed
Abu Attieh H, Halilovic M, Herr MAB, Hieber D 等
2026 May 21
置信度 0.82
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Healthcare infrastructures face escalating cybersecurity risks caused by legacy systems, connected IoMT devices, and complex data-sharing environments. Conventional intrusion detection and SIEM systems provide limited protection against zero-day and lateral-mo…
pubmed
Giannakopoulou O, Tarousi M, Androutsou T, Pitoglou S 等
2026 May 21
置信度 0.82
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Reliable access to laboratory and diagnostic data is essential for safe and equitable healthcare, yet laboratory data exchange remains fragmented across institution-specific infrastructures. Laboratory Information Management Systems (LIMS) and electronic healt…
pubmed
Bamunuge S, Haddad T, Khaddaj S, de Lusignan S 等
2026 May 21
置信度 0.82
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The secondary use of clinical routine data offers major opportunities for biomedical research but also poses challenges regarding data protection, interoperability, and coordination. Within the German Medical Informatics Initiative (MII), Data Integration Cent…
pubmed
Abu Attieh H, Jolly JK, Pallaoro P, de Arruda Botelho Herr M 等
2026 May 21
置信度 0.82
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In alignment with the European Health Data Space (EHDS), Spain's IMPaCT - Precision Medicine Infrastructure associated with Science and Technology - aims to establish a trusted research environment (TRE) for secure and FAIR data sharing and analysis. It is str…
pubmed
Rodríguez-Mejías S, Sánchez-Cabo F, Al-Shahrour F, Rosas C 等
2026 May 21
置信度 0.82
-
The INDICATE project, funded by the European Union under the Digital Europe Programme, develops a federated framework for the secure reuse of intensive care unit (ICU) data within the EHDS. This work presents the design of a privacy-preserving ETL dataflow tha…
pubmed
Parra Rodriguez-Armijo M, Alvarez-Romero C, van den Brand J, Delange B 等
2026 May 21
置信度 0.82
-
Efficient and semantically correct data exchange between healthcare systems remains a major challenge due to heterogeneous data models, legacy technologies, and inconsistent adoption of standards. This research investigates and develops an open-source integrat…
pubmed
Randmaa R, Bossenko I, Piho G, Ross P
2026 May 21
置信度 0.82
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Semantic standardization is essential, but not sufficient, to enable research over real-world data networks. Even when harmonized, differences in data availability, granularity, and clinical practice can introduce subtle biases that affect downstream analyses …
pubmed
Rubio Ruiz D, Muñoz Monjas A, Bermejo Bernardo P, Perez-Rey D 等
2026 May 21
置信度 0.82
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We introduce the FedDRAGON challenge, a federated learning benchmark for clinical natural language processing. The challenge includes 12 information extraction tasks where data is extracted from clinical reports from 4 Dutch care centers. Baseline results show…
pubmed
Abrahamsen BS, Bosma JS, Huisman H, Elschot M
2026 May 21
置信度 0.82
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This study presents a federated system developed within the SHIELD project, part of Horizon Europe's effort to reduce non-communicable diseases. It integrates retrospective and prospective clinical data using LLM-based multi-agent systems for automated ETL and…
pubmed
Lozano F, Sánchez Esquivel J, Paraíso-Medina S, Alonso-Calvo R 等
2026 May 21
置信度 0.82
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Multi-site medical studies require methods that address confounding bias while respecting data privacy regulations. We propose a federated learning method integrating propensity score matching (PSM) to achieve both objectives simultaneously. Using data from fi…
pubmed
Sheikhalishahi S, Schwinn J, Morhart M, Hinske LC 等
2026 May 21
置信度 0.82
-
We quantify how the per round client participation rate k affects performance and runtime in a federated learning study predicting two year confirmed disability progression in multiple sclerosis using routine clinical data. Using the original study's data, pre…
pubmed
Pirmani A, MSBase Study Group, Moreau Y, Peeters LM
2026 May 21
置信度 0.82
-
Hepatocellular carcinoma (HCC) is steadily increasing in incidence worldwide and requires data-driven approaches to improve diagnosis, prognosis, and therapeutic decisions. We describe the harmonization of IMALIVE -a real-world HCC cohort- with the common data…
pubmed
Guedjali A, Mondet K, Beaufrere A, Gregory J 等
2026 May 21
置信度 0.82
-
A common challenge in Federated Learning (FL) is that distribution shifts between clients, or Non-IIDness, decrease global model performance. Non-IIDness means that data is not independently and identically distributed between participating sites. Stronger dis…
pubmed
Weber L, Hauschild AC, Altenbuchinger M, Sax U 等
2026 May 21
置信度 0.82
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In clinical practice, the preoperative risk assessment of adrenal metastases versus benign adrenal lesions carries a substantial risk of misdiagnosis. The artificial intelligence technology holds promise for reducing misdiagnosis rates. However, due to the pro…
pubmed
Feng B, Yu Z, Chen Y, Xu J 等
2026 Sep
置信度 0.82
-
Artificial intelligence (AI) is transforming multi-omics analysis in small-molecule drug discovery by advancing vast datasets from genomics, transcriptomics, proteomics, and metabolomics to cover novel therapeutic targets and optimize lead compounds. Machine l…
pubmed
Soni S, Rathee S, Sreeharsha N, Vasdev N 等
2026
置信度 0.82
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Pneumonia is a severe lung infection triggered by various viral pathogens. Detecting and diagnosing pneumonia using clinical images is challenging because its visual features often resemble those of other pulmonary conditions. As a result, existing approaches …
pubmed
L L S M, Bharti P
2026 Jul 15
置信度 0.82
-
Inverse reinforcement learning (IRL) seeks to infer the latent reward function and the associated optimal policy from expert demonstrations. However, most current IRL methods assume centralized access to all trajectory data, which is impractical in real-world …
pubmed
Jiang G, Hong S, Imani M, Bastian ND 等
2026 May 19
置信度 0.82
-
Space biology research increasingly requires integrated platforms capable of managing complex datasets. This chapter introduces the NASA Open Science Data Repository (OSDR), designed to unify multiomics, physiological, environmental telemetry, and radiation ex…
pubmed
Sanders LM, Costes SV
2026
置信度 0.82
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The process of migration of IoMT systems in healthcare into post-quantum cryptographic systems is expected to be a gradual one. Here, existing ECC-based devices alongside newly developed quantum-resistant devices will be operating within the same healthcare ec…
pubmed
Khan UH, Khan R, Chelloug SA, Alturise F 等
2026
置信度 0.82
-
Machine learning (ML) has the potential to enhance surgical decision-making through real-time risk prediction and personalised care yet clinical implementation remains limited. This study aimed to identify and categorise the key barriers to implementing ML too…
pubmed
Ben Hmido S, Garita C, Bloemers F, Rozie S 等
2026 May 18
置信度 0.82
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Spaceflight exposes humans to unique stressors that remodel biology. Space health is emerging as a data science discipline grounded in multiomic atlases, harmonized biobanks, and open, findable, accessible, interoperable, and reusable (FAIR)-aligned infrastruc…
pubmed
Willett JDS, Kim J, Sakharkar A, Park J 等
2026 Aug
置信度 0.82
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Federated learning (FL) enables multiple clients to train models on local data and collaboratively optimize a global model without sharing raw data. However, client heterogeneity, such as differences in data distributions and system capabilities, poses challen…
pubmed
Li J, Xiao R, Yu L, Zhang K 等
2026 May 18
置信度 0.82
-
Cognitive impairment arising from ischemic stroke, Alzheimer's disease, and Parkinson's disease presents distinct structural and network-level alterations. Brain magnetic resonance imaging offers a non-invasive and high-resolution approach to assess these chan…
pubmed
Xu Q, Lu J, Zhang Z, Xu D 等
2026 Sep 1
置信度 0.82
-
The application of Machine Learning (ML) to the diagnosis of rare diseases, such as collagen VI-related dystrophies (COL6-RD), is fundamentally limited by the scarcity and fragmentation of available data. Attempts to expand sampling across hospitals, instituti…
pubmed
Brull A, Aguti S, Bolduc V, Hu Y 等
2025 Dec 18
置信度 0.82
-
Lung cancer is the most lethal malignancy worldwide, largely due to its late detection after its progression to advanced stages. Over the last decade, artificial intelligence (AI) applications have shown significant potential in transforming lung cancer diagno…
pubmed
Hu W, Wang G, Ren L, Hu J 等
2026 Apr 30
置信度 0.82
-
Despite growing understanding of the benefits of having Findable, Accessible, Interoperable, and Reusable (FAIR) data, many datasets still cannot be shared. Federated analysis methods can enable multisite studies that do not require the sharing of participant-…
pubmed
Wang M, Bhagwat N, Cremonesi F, Dugré M 等
2026
置信度 0.82
-
As the National Institute for Pharmaceutical Technology and Education (NIPTE) marks its 20th anniversary, the pharmaceutical ecosystem faces a widening gap between regulatory "risk-to-quality" compliance and real-world "risk-to-patient" outcomes. This Perspect…
pubmed
Hussain AS, Morris K, Gurvich VJ
2026 May 15
置信度 0.82
-
Cardio-Vascular Diseases (CvDs) persist as a significant mortality reason worldwide, which requires advanced risk categorization technologies that can offer custom medicine while protecting patient information. Present healthcare approaches must overcome fragm…
pubmed
Sivakami R, Kumar VV, Krishnamoorthy N, Yimer TE
2026 May 16
置信度 0.82
-
Digital technologies are revolutionizing healthcare, particularly in Remote Health Monitoring (RHM). RHM uses digital tools to monitor patients’ health data outside traditional clinical settings, allowing for continuous real-time management. This approach has …
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Abstract Federated learning is a new learning paradigm that decouples data collection and model training via multi-party computation and model aggregation.As a flexible learning setting, federated learning has the potential to integrate with other learning fra…
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In the past few decades, machine learning has revolutionized data processing for large scale applications. Simultaneously , increasing privacy threats in trending applications led to the redesign of classical data training models. In particular, classical mach…
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Federated learning (FL) at the edge is emerging as a cornerstone of next-generation AI, particularly in the era of 5G and 6G connectivity. This chapter explores how FL enables distributed devices and edge servers to collaboratively train AI models across massi…
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