空间计算 · 全部实体（第 30 / 100 页）

本页收录第 2901–3000 条，共 10000 条 · 返回 空间计算 首页

• Integrating multi-omics data for next-generation cancer research and precision medicine.
  Multi-omics is the coordinated acquisition, integration, and interpretation of multiple datasets generated from diverse molecular layers of a biological system, intending to capture a comprehensive understanding of interactions between molecular hierarchies an…
  pubmed Biswas S, Acharya S, Prajapat A, Sen P 等 2026 May 20 置信度 0.82
• Fuzzy multi-criteria selection of sensor architectures for coastal pollution monitoring.
  This paper evaluates five sensor network architectures for coastal marine pollution monitoring using a fuzzy multi-criteria decision-making framework. Thirty domain experts assessed the alternatives against five criteria (detection performance, spatial coverag…
  pubmed Jiaolong F, Saad NHM, Park J 2026 May 20 置信度 0.82
• Data fusion in air pollution exposure assessment: Methods, applications, and future directions.
  Over the past two decades, major advances in observational techniques and modeling capabilities have enabled the development of air pollution data fusion methods that integrate information from regulatory monitoring networks, low-cost sensors, satellite remote…
  pubmed Liu Y, Chang HH, Fu JS 2026 Jun 置信度 0.82
• Pioneer: Dynamical Systems Biology for Spatiotemporal Omics Data.
  Dynamical systems biology is an emerging interdisciplinary framework that aims to understand how complex biological processes arise from time-dependent interactions among molecular, cellular, and tissue-level components. The rapid development of high-throughpu…
  pubmed Chen L 2026 Oct 1 置信度 0.82
• Mechanisms of transcranial magnetic brain stimulation.
  Transcranial magnetic stimulation (TMS) noninvasively activates the human cortex through the intact skull and is now employed worldwide to interrogate physiological and pathological functions of the human brain and to treat a variety of neurological and psychi…
  pubmed Massimini M, Peterchev AV, Vlachos A, Ziemann U 2026 Oct 1 置信度 0.82
• AI-powered digital innovations in pharmaceuticals research & development: Current landscape and case examples.
  Artificial intelligence (AI)-powered digital innovations are increasingly reshaping pharmaceuticals and research and development. While AI/ML techniques are now widely accessible, some of the work on Large Language Models (LLMs) and other aspects of digital in…
  pubmed Li X, Dai J, Pang H 2026 May 18 置信度 0.82
• Integrated pragmatic approach of bioinformatics and cheminformatics for tracking the fecal pollution in an urban marine environment.
  Fecal contamination in urban marine environments poses an alarming global threat to public health, ecosystems, and economies. Traditional fecal indicator bacteria (FIB) methods, while accessible, suffer from delayed results and inability to differentiate pollu…
  pubmed Fulke AB, Ratanpal S 2026 May 18 置信度 0.82
• Pre-clinical SPECT and SPECT-CT in Oncology.
  Molecular imaging enables both spatial and temporal understanding of the complex biological systems underlying carcinogenesis and malignant spread. Single photon emission computed tomography (SPECT) is a versatile nuclear imaging technique with ideal propertie…
  pubmed Seo Y, Zannoni EM 2026 置信度 0.82
• Differential diagnosis of benign and malignant pulmonary nodules attached to the interlobar pleura.
  Pulmonary nodules attached to the interlobar pleura (PNs-AIP) represent a distinct subset of pulmonary nodules (PNs), for which accurate differentiation between benign and malignant status is critical for guiding clinical decisions. Chest computed tomography (…
  pubmed Yang XY, Liao JC, Li X, Wang Y 等 2026 May 1 置信度 0.82
• Deep ensemble optimized models for probabilistic CTV breast segmentation.
  To optimize radiotherapy treatment and minimize toxicities, effective segmentation of organs-at-risk (OARs) and clinical target volume (CTV) is essential. Deep learning (DL) models can achieve high segmentation accuracy through careful tuning. However, their r…
  pubmed Riani C, Ubeira-Gabellini MG, Palazzo G, Ricciardi G 等 2026 置信度 0.82
• Collimator position optimization for proton minibeam radiation therapy.
  Proton minibeam radiation therapy (pMBRT) employs spatially fractionated dose distributions to reduce normal tissue toxicity. A key component is the multi-slit collimator (MSC), which shapes the beam into narrow, spatially separated minibeams. Small lateral sh…
  pubmed Shinde N, Lin Y, Gao H 2026 May 15 置信度 0.82
• Automated Global Positioning Layout (GPL) for accuracy assessment in CAD-CAM mandibular reconstruction - method introduction.
  Assessing accuracy in CAD-CAM mandibular reconstruction poses significant challenges but is essential for ensuring reliable outcomes. Existing methods are often operator-dependent, lacking repeatability and reproducibility. This study introduces the Global Pos…
  pubmed Vargiu E, Menapace G, Bettini G, Tognin L 等 2026 May 15 置信度 0.82
• The role of citizen science in mosquito-borne disease surveillance and control: A scoping review.
  Mosquito-borne diseases (MBDs) pose substantial global health and economic burdens. Although conventional MBDs surveillance systems remain essential, they are often resource-intensive, uneven in coverage, and often insufficiently responsive to spatio-temporal …
  pubmed Kianfar N, Savoji K, Huang X, Yang D 等 2026 置信度 0.82
• Estimating tumour immune infiltration: methodological convergence across histology and spatial technologies.
  Estimating tumour immune infiltration is critical for understanding cancer biology and predicting patient response to surgery and immunotherapy. A wide array of experimental platforms supports various computational approaches for quantifying tumour-infiltratin…
  pubmed Bian B, Cao Y, Yang JYH 2026 May 4 置信度 0.82
• Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review).
  Cancer signaling networks, highly dynamic with interconnected systems, regulate tumor initiation, its progression, therapeutic response and drug resistance. Rather than functioning as isolated pathways, these networks integrate extracellular and intracellular …
  pubmed Li H, Song S, Wang L, Liu Q 2026 Jul 置信度 0.82
• A single-cell and spatial atlas of plaque macrophage states in human atherosclerosis.
  Human atherosclerosis is increasingly recognized as a spatially organized inflammatory disease in which macrophages act as central regulators of lesion evolution rather than as a uniform foam-cell population. Recent single-cell and spatial profiling studies ha…
  pubmed Yang Y, Zhu H 2026 置信度 0.82
• Multi-omics insights into immune tolerance at the maternal-fetal interface in recurrent pregnancy loss: mechanisms, integration challenges, and translational perspectives.
  Recurrent pregnancy loss (RPL) is a heterogeneous reproductive disorder in which dysregulation of maternal-fetal immune tolerance, aberrant decidual immune remodeling, and altered inflammasome signaling have been implicated within a complex multi-omics landsca…
  pubmed Shao M, Zhang Y, Tang H, Zhou Z 等 2026 置信度 0.82
• LADAS: A Localization-Adaptive Dual-Branch Framework for Accurate Delineation of Teeth and Jaw Bone in Axial CBCT Slices.
  Accurate delineation of teeth and jaw bone in cone-beam computed tomography (CBCT) is essential for digital dental diagnosis, treatment planning, and surgical navigation. However, reliable segmentation remains challenging due to imaging noise, blurred boundari…
  pubmed Liu L, Guo H, Lai L, Min F 等 2026 May 14 置信度 0.82
• Dual-Phase Computed Tomography-Based Deep Learning Architecture for Three-Year Survival Prediction in Hepatocellular Carcinoma.
  Hepatocellular carcinoma (HCC) is a major global health burden, ranking as the sixth most common cancer and the third leading cause of cancer-related mortality. Computed tomography (CT) is widely used for HCC evaluation because of the high spatial resolution a…
  pubmed Wang YW, Huang TC, Chiang SY, Chen YJ 等 2026 May 14 置信度 0.82
• Innovative technologies and future perspectives in tumor microbiomics.
  Microorganisms within the tumor microenvironment represent an important but still underexplored dimension of cancer biology, influencing genomic stability, immune responses, metabolism, and therapeutic efficacy. Although recent findings underscore the signific…
  pubmed He WT, Xing X, Wang F, Li L 等 2026 Aug 置信度 0.82
• Improved CNN with BiLSTM model for early melanoma and skin lesion classification.
  Melanoma contributes to approximately 1% of all skin cancer cases but accounts for the majority of the deaths due to its aggressive behavior and high metastatic potential. Traditional diagnostic methods, including dermoscopy via the ABCDE rule, tend to be subj…
  pubmed Rajeshkumar S, Chowdhary CL 2026 置信度 0.82
• Functional system-specific brain aging across the Alzheimer's disease continuum.
  Accelerated brain aging is implicated in Alzheimer's disease (AD). However, the spatial heterogeneity of brain aging patterns across different functional systems along the AD continuum remains largely unexplored. We developed functional system-specific brain a…
  pubmed Huo Y, Huang W, Liu Z, Chen H 等 2026 May 13 置信度 0.82
• Recent Advances in the Development of CRISPR-Based Live-Cell Molecular Imaging and Sensing.
  Visualizing genome organization and transcriptional dynamics with spatial and temporal precision in living cells is essential for elucidating gene regulation and chromatin-associated disease mechanisms, yet conventional methods confront a fundamental tension b…
  pubmed Hou M, Li Y, Wu X, Long D 等 2026 Jun 置信度 0.82
• Roles for specialized secretory epithelial cells in inflammatory bowel disease.
  Current inflammatory bowel disease (IBD) therapies mainly target immune pathways, yet many patients fail to achieve durable remission, highlighting the need to understand epithelial-intrinsic drivers of chronic inflammation and barrier defects. Recent single-c…
  pubmed Huang Z, Brown ME, Lau KS 2026 Jul 1 置信度 0.82
• Next-Generation Artificial Intelligence Strategies for Mechanistic Cancer Target Discovery and Drug Development: A State-of-the-Art Review.
  Artificial intelligence (AI) is increasingly used in cancer research, enabling integrative analysis of complex biomedical data to identify actionable therapeutic vulnerabilities. This review specifically examines how AI advances mechanistic cancer target disco…
  pubmed Khan MS, Saeed M, Arham M, Zafar I 等 2026 Apr 30 置信度 0.82
• Bridging Traditional Modeling and Artificial Intelligence in Measles Epidemiology: Methods, Applications, and Future Directions-A Narrative Review.
  Measles remains one of the most contagious infectious diseases globally and continues to pose substantial public health risks despite decades of effective vaccination. This narrative review examines both classical and contemporary computational approaches used…
  pubmed Baiasu AF, Rotaru-Zavaleanu AD, Boldea AM, Ruscu MA 等 2026 Apr 24 置信度 0.82
• Microglia Reprogramming in Glioblastoma: Stem Cell-Derived Factors as Emerging Immunomodulators.
  Glioblastoma (GBM) remains one of the most challenging forms of cancer to treat, despite that extensive molecular profiling is now available. Indeed, intratumoral cellular heterogeneity, receptor redundancy, and adaptive resistance through compensatory signali…
  pubmed Amiri Z, Tremonti BF, Corsaro A, Pattarozzi A 等 2026 May 4 置信度 0.82
• Serial brain FDG-PET and IMZ-SPECT following intracerebral MSC transplantation in patients with subacute ischemic stroke.
  Ischemic stroke is a leading cause of mortality and long-term neurological disability worldwide, and cell-based therapies represent a promising approach. Although clinical studies have reported favorable outcomes following cell transplantation, the effects on …
  pubmed Kawabori M, Hirata K, Shichinohe H, Watanabe S 等 2026 May 12 置信度 0.82
• Effectiveness of real-time dynamic navigation in third molar extraction: a systematic review.
  Impacted third-molar surgery can be technically challenging because of anatomical variability and proximity to critical neurovascular structures, which may increase operative difficulty and the risk of complications. Real-time dynamic navigation (RDN) has been…
  pubmed Aziz MN, Nasher AT, Al-Aroomi OA 2026 May 13 置信度 0.82
• From tarsal anatomy to tear-film homeostasis: A history-informed review of the meibomian gland in ocular surface biology.
  The meibomian gland was anatomically described in 1666, but its central role in ocular surface disease emerged only after tear-film physiology, in vivo imaging, lipid biochemistry, and consensus nosology converged. This review reconstructs the transition from …
  pubmed Zhang J, Li Z 2026 Aug 置信度 0.82
• Innate lymphoid cells in rheumatoid arthritis as mediators of pathology and resolution.
  Innate lymphoid cells (ILCs) are emerging as critical modulators of inflammation in rheumatoid arthritis, contributing to both disease pathology and resolution. Group 3 ILCs (ILC3s) mirror T H 17 cells in their production of IL-17A and IL-22, promoting fibrobl…
  pubmed Kabil AK, Kuo IC, Colonna M, McNagny KM 2026 Jun 置信度 0.82
• Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.
  Mammalian sensory systems are traditionally viewed as hierarchical pathways in which subcortical nuclei relay signals from peripheral receptors to the cortex, where sensory information is contextualized for perception and behaviour. However, the auditory pathw…
  pubmed Lohse M, Willmore BDB, King AJ 2026 Jul 置信度 0.82
• Thematic Mapping and Evolution of Social Media Mining in Health Research: Hybrid Bibliometric Synthesis.
  Social media platforms offer extensive data, as they are widely used globally. Social media mining (SMM) enables real-time monitoring of user-reported health information and serves as a supplement to traditional health data analytics. However, the rapid prolif…
  pubmed Yang MJ, Bohnet-Joschko S 2026 May 8 置信度 0.82
• Computational neuroelectrophysiology and artificial intelligence for drug-resistant epilepsy: recent advances, current challenges, and future directions.
  Drug-resistant epilepsy (DRE) affects approximately 30% of epilepsy patients, with surgical cure rates below 70%. This challenge drives a fundamental paradigm shift from localizing a discrete epileptogenic zone toward characterizing and modulating the dysfunct…
  pubmed Wang Y, Yan Z, Gong Y, Lin W 等 2026 Jun 9 置信度 0.82
• Photon-counting CT in cardiac imaging: multi-institutional guidance on technical principles, clinical evidence, and practical protocols.
  Coronary CT angiography (CCTA) is recommended as a first-line test for evaluating suspected coronary artery disease in many patient cohorts. Photon-counting detector CT (PCD-CT) introduces direct energy discrimination, higher geometric dose efficiency, and ult…
  pubmed Hagar MT, Vecsey-Nagy M, Kravchenko D, Halfmann MC 等 2026 Aug 置信度 0.82
• Multidimensional dissection of shared genetic susceptibility in ulcerative colitis and colorectal cancer: novel insights from integrative single-cell and multi-omics analysis.
  Ulcerative colitis (UC) patients carry a 2.5-fold increased risk of colorectal cancer (CRC), yet the shared multi-scale genetic architecture remains poorly understood. We constructed an integrative framework across tissue, cellular, and variant levels to syste…
  pubmed Zhu F, Yao X, Liu D, Wang S 等 2026 May 11 置信度 0.82
• Mapping the immune environment: spatiotemporal dynamics in cardiovascular events.
  Cardiovascular disease remains a leading cause of global mortality despite advances in revascularization, pharmacotherapy, and risk stratification. Immune responses to cardiovascular damage are neither temporally linear nor spatially homogeneous; they evolve a…
  pubmed Dinc R, Ardic N 2026 置信度 0.82
• Observing the invisible: X-ray CT for plant-microbe interactions.
  Plant-microbe interactions are inherently spatial, yet the physical structure of the soil and rhizosphere is rarely treated as a mechanistic variable in experimental design. X-ray computed tomography (X-ray CT) enables nondestructive, three-dimensional, and ti…
  pubmed Pereira EC, Bell CA 2026 Aug 置信度 0.82
• Advances in Radiological Imaging for Thoracic Oncology: A 20-Year Perspective.
  Lung cancer remains the leading cause of cancer-related mortality worldwide, underscoring the critical role of imaging in early detection, staging, and treatment planning. In the past 2 decades, thoracic imaging has evolved from anatomical visualization to mul…
  pubmed Erasmus JJ, Vlahos I 2026 May 置信度 0.82
• THE ROLE OF 3D MODELING IN THE SURGICAL MANAGEMENT OF HIATAL HERNIAS: A LITERATURE REVIEW.
  Surgical treatment of hiatal hernia (HH) and concomitant gastroesophageal reflux disease (GERD) remains one of the most complex and controversial areas of modern abdominal surgery. Traditional two-dimensional imaging techniques, such as radiography and convent…
  pubmed Khorobrykh T, Agadzhanov V, Kadirov D, Ivashov I 等 2026 Mar 置信度 0.82
• A Systematic Review: The Application of Attention Mechanisms in Medical Ultrasound Image Processing.
  Among numerous medical imaging modalities, ultrasound imaging is one of the most commonly used diagnostic methods in clinical practice. However, ultrasound diagnosis heavily relies on physician experience, and diagnostic results often lack reproducibility. In …
  pubmed Feng W, Sun S, Xue Z, Shi Y 等 2026 Aug 置信度 0.82
• Higher order visual processing in the visual cortex.
  This chapter covers how the cortex combines visual signals from parallel retinocortical channels into perceptually useful neural representations. The retina sends signals to the visual cortex about the surfaces of objects, including shape, lightness and color,…
  pubmed Shapley R 2026 置信度 0.82
• Machine learning-based integration of transcriptome and digital pathology for predicting chemoresistance in muscle-invasive bladder cancer.
  Muscle-invasive bladder cancer (MIBC) presents with variable clinical and pathological features, leading to inconsistent responses to standard treatments such as neoadjuvant chemotherapy (NAC). Although transcriptome profiling has shown differences in NAC resp…
  pubmed Jeong J, Jeong G, Kim Y, Ju H 等 2026 May 置信度 0.82
• Photon-counting CT in gastrointestinal malignancies: a scoping review.
  Photon-Counting computed tomography(PCCT) offers superior spatial resolution, improved contrast-to-noise ratio and reduced radiation dose compared with conventional CT. This scoping review maps and synthesizes clinical evidence on PCCT applications in gastroin…
  pubmed Spoto F, Robertis R, Monterubbiano L, Sala G 等 2026 Aug 置信度 0.82
• The lung in acute respiratory failure: insights from synchrotron radiation imaging.
  Acute respiratory failure and the acute respiratory distress syndrome (ARDS) are characterized by profound spatial and temporal heterogeneity in lung aeration, mechanics, and inflammation. While mechanical ventilation is often vital to ensure gas exchange, it …
  pubmed Bayat S, Albu G, Fardin L, Bravin A 2026 May 8 置信度 0.82
• Integrative circulatory engineering for regenerative therapy: Dynamic perfusion design and metabolic maturation in cardiac tissue engineering.
  The adult myocardium couples extreme metabolic demand with a finely tuned coronary microvasculature. Continuous, high-work output is sustained by dense capillary networks, short diffusion distances and dominant reliance on mitochondrial oxidative phosphorylati…
  pubmed Homma J, Sekine H 2026 Jun 置信度 0.82
• A Vein Attempt? Experimental Models for Arteriovenous Fistula Research.
  Chronic kidney disease (CKD) affects more than 10% of adults worldwide and is associated with rising mortality and increasing demand for hemodialysis. Hemodialysis requires durable vascular access, with surgically created arteriovenous fistulas (AVFs) being th…
  pubmed Shah NA, Li CD, Thomas SD, Varcoe RL 等 2026 Aug 置信度 0.82
• Deciphering spatial-temporal mechanisms of PD-1 blockade resistance via biologically informed machine learning.
  Immune checkpoint inhibitors (ICIs), especially PD-1/PD-L1 blockade, have transformed cancer therapy; yet objective response rates to anti-PD-(L)1 monotherapy remain ∼20-30% and resistance is common. Meanwhile, multi-omics, spatial profiling, imaging, a…
  pubmed He L, Zhao M, Hu Y, Chen L 等 2026 Aug 1 置信度 0.82
• Fibroblast activation protein-targeted molecular imaging in interstitial lung disease: a systematic review.
  Interstitial lung diseases (ILDs) are characterized by progressive lung scarring. Fibroblast activation protein (FAP), overexpressed on activated fibroblasts, has emerged as a key molecular target for imaging active fibrosis. This systematic review synthesizes…
  pubmed Olya AG, Bahtouee M, Jafari E, Ravanipour M 等 2026 Sep 置信度 0.82
• Deep learning techniques for early detection and classification of leaf diseases in crops.
  Rapid population growth and climate change have intensified the need for sustainable agricultural productivity. Plant leaf diseases significantly impact the crop yield, quality, and food safety, necessitating accurate and automated detection methods.
  pubmed Srinivasu PN, Anirudh V, Kamali DL, Lalitha Kumari S 等 2026 置信度 0.82
• Illuminating compartmentalized AMPK signaling in single cells.
  AMP-activated protein kinase (AMPK) is a crucial regulator of cellular energy balance, affecting numerous downstream targets across various subcellular locations. Under cellular energy stress, AMPK becomes fully activated when it binds AMP and is phosphorylate…
  pubmed Jhawar A, Parks K, Schmitt DL 2026 Jun 3 置信度 0.82
• The ARTEMIS trial identifies immune activation as a key predictor of neoadjuvant chemotherapy response in triple-negative breast cancer.
  Selecting treatments for triple-negative breast cancer (TNBC) remains challenging due to its high molecular and phenotypic heterogeneity. To maximize response rates, nearly all patients are treated with an aggressive combination of chemo-immunotherapy. However…
  pubmed Seth S, Yam C, Huo L, Lim B 等 2026 May 6 置信度 0.82
• Mass Spectrometry Based Multi-Omics Integration: Analytical Methods and Biological Applications.
  Biological systems are regulated through strongly interconnected molecular layers that cannot be accurately resolved using single-omics approaches. Although genomics and transcriptomics provide essential regulatory information, they often face obstacles to ref…
  pubmed Battineni JK, Mamidisetti YD, Kuchukuntla M, Amaravadi D 等 2026 Aug 15 置信度 0.82
• Multi-omics insights into tumor grade progression in clear cell renal cell carcinoma: from molecular mechanisms to precision therapeutics.
  Clear cell renal cell carcinoma (ccRCC) can transition from indolent, low-grade lesions to high-grade, lethal disease through a layered cascade of genomic, epigenomic, metabolic, and immune remodeling. The initiating event in ∼90% of ccRCC is loss of ch…
  pubmed Jena RS, Mishra A 2026 置信度 0.82
• Transcriptomics and AI-driven approaches to the diagnosis and treatment of rheumatoid arthritis.
  Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder marked by joint swelling, pain, and progressive tissue destruction. Increasing evidence suggests that dysregulated RNA expression critically drives RA progression by perturbing immune, inf…
  pubmed Ciechomska M, Oldak M, Massalska M 2026 置信度 0.82
• Attention mechanisms in UNet variants for medical/non-medical image segmentation: A comprehensive and state-of-the-art narrative review.
  This review examines enhancements to the U-Net's ability to represent complex spatial structures for segmentation through attention mechanisms. The study surveys applications across both medical and non-medical domains, focusing on cSAM, cCAM, CBAM, and their …
  pubmed Gupta S, Chhetri Y, Pandey A, Singh A 等 2026 Jul 1 置信度 0.82
• Ses: a Swin-Unet Edge-aware Segmentation network for uterine fibroid ultrasound images.
  Uterine fibroids represent one of the most prevalent gynecological tumors; however, their ultrasound images frequently exhibit indistinct boundaries and complex morphologies, thereby complicating accurate segmentation. An enhanced Swin-Unet-based framework, de…
  pubmed Wang X, Shi L, Wang W, Guo L 2026 May 4 置信度 0.82
• Learning patient-specific spatial biomarker dynamics via operator learning for Alzheimer's disease progression.
  Alzheimer's disease (AD) is a complex, multifactorial neurodegenerative disorder with substantial heterogeneity in progression and treatment response. Despite recent therapeutic advances, predictive models capable of accurately forecasting individualized futur…
  pubmed Wang J, Mao Y, Liu X, Hao W 等 2026 May 4 置信度 0.82
• Augmented Reality and Artificial Intelligence for the Assessment and Rehabilitation of Spatial Neglect: A Systematic Review.
  Augmented reality (AR) and artificial intelligence (AI) have been applied to the assessment and rehabilitation of post-stroke spatial neglect (SN). This study aims to evaluate the feasibility, effectiveness, degree of personalization, and ecological validity o…
  pubmed Li S, Chong B, Mehri-Kakavand G, Shi C 等 2026 Aug 置信度 0.82
• A vessel-guided multi-task deep learning framework with visual interpretability for simultaneous retinal vessel segmentation and multi-disease classification from fundus images.
  Retinal diseases represent a leading cause of visual impairment and blindness worldwide, with early and accurate diagnosis being crucial for preventing irreversible vision loss. Although deep learning techniques have achieved significant advances in fundus ima…
  pubmed Li Q, Tao L 2026 置信度 0.82
• Vision-Based Artificial Intelligence for Adaptive Peen Forming: Sensing Architectures, Learning Models, and Closed-Loop Smart Manufacturing.
  Peen forming is a dieless manufacturing process used to shape large, thin aerospace panels through controlled shot impacts that induce residual stresses and curvature. Despite long-standing industrial use, process monitoring still depends largely on indirect p…
  pubmed Farooq SS, Rehman A, Al-Yarimi FAM, Park S 等 2026 Apr 16 置信度 0.82
• Single-Cell Multi-Omics Reveal Gene Regulatory Mechanisms Underlying Cardiac Embryonic Development.
  Background/Objectives: Cardiac embryonic development is a highly coordinated and dynamic process governed by precise spatiotemporal gene regulation. Increasing evidence indicates that cellular heterogeneity and lineage specification during heart development ar…
  pubmed Feng E, Zheng X, Zhu F, Xiang L 等 2026 Mar 31 置信度 0.82
• Artificial Intelligence-Assisted Detection of Canine Impaction, Localization, and Classification from Panoramic Images: A Diagnostic Accuracy Comparative Study with CBCT.
  Background/Objectives: This study aimed to develop and evaluate deep learning models for the detection, localization, and classification of impacted maxillary canines, and to compare their performance with cone-beam computed tomography (CBCT) as the reference …
  pubmed Helal NM, Aljehani AF, Alomari SA, Mahmoud RA 等 2026 Apr 4 置信度 0.82
• Rule-based semi-automated method to segment black hole multiple sclerosis lesions on post-gadolinium 2D T1-weighted brain images.
  To develop a semi-automated method to segment "black hole" lesions on post-gadolinium 2D T1-weighted images (GdT1) in multiple sclerosis (MS) that follows radiological intensity rules and perform multi-center validation.
  pubmed Mattiesing RM, Groeneveld FA, Brouwer I, van Schijndel RA 等 2026 Sep 置信度 0.82
• Human brain fingerprint-like nodes within RSFC: an exploratory study and their role in RSFC-behavior associations.
  Resting-state functional connectivity (RSFC) contains participant-specific patterns that can support differentiation among individuals within a cohort. This paper proposed computational approaches for determining the differential identifiability of nodes withi…
  pubmed Feng P, Jing B, Dong R, Qi B 等 2026 May 2 置信度 0.82
• GNN-ML-FRL: a graph-enhanced meta-adaptive federated learning framework for scalable pest identification and ernvironmental modeling.
  Heterogeneous agro-ecological factors, insect breeding, and climate change are serious challenges to sustainable agricultural management. The study proposes a graph-enhanced meta-adaptive federated learning framework (GNN-ML-FRL) to address the challenges in p…
  pubmed Mahalakshmi, T S, Mathivanan SK, R S 等 2026 May 1 置信度 0.82
• Physics-Informed Machine Learning in Biomedical Science and Engineering.
  Physics-informed machine learning (PIML) is emerging as a potentially transformative paradigm for modeling complex biomedical systems by integrating parameterized physical laws with data-driven methods. Here, we review three main classes of PIML frameworks: ph…
  pubmed Ahmadi N, Cao Q, Humphrey JD, Karniadakis GE 2026 May 置信度 0.82
• Deep Learning for Cardiac Image Analysis: Unveiling Advances in Deep Learning Architectures.
  Deep learning (DL) continues to advance cardiac image analysis with increasingly sophisticated methodologies. Although convolutional neural networks laid the foundation for DL, emerging methods including graph neural networks, transformers, implicit neural rep…
  pubmed van der Zande JL, Alvarez-Florez L, Volleberg RHJA, Brás C 等 2026 Apr 24 置信度 0.82
• Navigating the Labyrinth of Hepatocellular Carcinoma: Leveraging AI/ML for Precision Oncology.
  Hepatocellular carcinoma (HCC) remains a significant global health challenge, with therapeutic efficacy in advanced stages often limited by underlying liver dysfunction and adaptive resistance. In this review, the evolving landscape of molecular targets and co…
  pubmed Manan A, Ilyas S 2026 置信度 0.82
• Spatial AI in cancer: mapping immune evasion topology through multi-modal omics and deep learning.
  Immune checkpoint blockade has transformed cancer therapy, achieving lasting responses in some patients, yet most still encounter primary or acquired resistance. Recent evidence demonstrates that this resistance is driven not only by intrinsic cellular feature…
  pubmed Lang L, Cui Y, Wang H, Xiao Y 2026 置信度 0.82
• Robot-assisted pedicle screw placement by using optical navigation.
  Pedicle screw placement is the gold standard for spinal pathologies that require surgical stabilization. Accurate screw placement is important to avoid severe complications, but ensuring accuracy remains a challenge. This work proposes an optical camera-based …
  pubmed Davoodi A, Li R, Massalimova A, Carrillo F 等 2026 置信度 0.82
• Bosworth fracture-dislocation of the ankle: a case report and literature review.
  Bosworth fracture-dislocation is a rare and specific variant of ankle injury. Its insidious radiographic features frequently lead to a high clinical misdiagnosis rate. Furthermore, the entrapment of the proximal fibular fracture fragment behind the posterolate…
  pubmed Lin S, Zhuo H, Gong Y, Shen X 等 2026 置信度 0.82
• Comparing the detectability of pulmonary nodules on two ultra-high resolution CT scanners: a preliminary phantom study.
  To objectively and subjectively compare the detectability of pulmonary nodules on an ultra-high-resolution CT (UHR-CT) scanner equipped with energy-integrating detectors and a photon-counting CT (PCCT) in UHR mode.
  pubmed Greffier J, Salvat C, Pastor M, Villani N 等 2026 Sep 置信度 0.82
• From peripersonal space to cognitive maps: An evolutionary perspective.
  Our brains support at least two major spatial representations: an egocentric, short-horizon representation of peripersonal space (PPS), and an allocentric, longer-horizon cognitive map system. Here, we speculate on their relationship from an evolutionary persp…
  pubmed Anjum S, Sosa MJ, Serino A, Noel JP 2026 Jul 置信度 0.82
• Neonatal brain MRI Atlas: Current and future.
  Neonatal brain atlases provide essential spatial references for studying early brain development and supporting atlas-based neuroimaging analysis. This paper presents a comprehensive review of the methodological evolution of neonatal brain template constructio…
  pubmed Zhai H, Gao H, Zhuo X, Chen Y 等 2026 Sep 置信度 0.82
• Novel Approaches for Investigating Host Responses to HIV Infection in Ex Vivo Human Genital Tissues.
  Understanding local immune responses and the structural integrity of the genital mucosal barrier is essential for advancing knowledge of both susceptibility to sexual HIV transmission and the pathogenesis of chronic HIV infection. This review highlights innova…
  pubmed Boger MF, Kaldhusdal V, Broliden K 2026 May 置信度 0.82
• The emerging role of ¹⁸F-NaF PET/CT in osteoporosis: an emphasis on its application for the evaluation and management of lumbar spine osteoporosis.
  Osteoporosis is a chronic skeletal disorder characterized by reduced bone mineral density and disrupted bone microarchitecture, affecting over 200 million individuals worldwide. The lumbar spine, containing the largest volume of metabolically active trabe…
  pubmed Gujral J, Gandhi OH, Amanullah AA, Dagli MM 等 2026 Apr 29 置信度 0.82
• Deep Learning for Cardiac Wall Motion Analysis: A Review of Methods, Challenges, and Clinical Applications.
  Abnormalities in cardiac wall motion are strong predictors of cardiovascular risk, making their accurate detection essential for early diagnosis and effective clinical management. Traditional imaging modalities such as echocardiography, magnetic resonance imag…
  pubmed Monfared M, Kakavand B, Taebi A 2026 Apr 29 置信度 0.82
• Application of upright multidetector CT in orthopedics and the musculoskeletal system: insights into anatomy, alignment, and biomechanics.
  Upright multidetector CT (MDCT) enables whole-body, high-resolution, three-dimensional cross-sectional imaging in standing or sitting positions, providing detailed visualization of anatomy and biomechanics in physiologically relevant, load-bearing postures. Th…
  pubmed Yamada Y, Yamada M, Yokoyama Y, Kaneda K 等 2026 Aug 置信度 0.82
• Breaking the Limits of Low-Field MRI: Deep Learning Approaches to Image Enhancement.
  Low-field magnetic resonance imaging (LF-MRI) has emerged as a transformative technology, offering portable and cost-effective solutions for medical imaging in resource-limited settings. However, LF-MRI systems face inherent challenges, including low signal-to…
  pubmed Zhu X, Shang Y, Yang HJ, Yang L 等 2026 Jun 置信度 0.82
• Spatial transcriptomics atlas of inflammatory bowel disease to guide implementation in research consortiums and clinical trials.
  Using over 100 intestinal tissue sections from non-diseased controls and patients with ulcerative colitis or Crohn's disease across multiple inflammatory bowel disease consortia, we construct a spatially resolved atlas containing over three million cells and s…
  pubmed Li Y, Wei C, Yang W, Wang H 等 2026 Apr 28 置信度 0.82
• DUST: A framework for quantifying dugong-seagrass interactions using low-cost UAVs.
  Seagrass ecosystems are crucial to global environmental health, food security, and provide ecosystem services such as CO 2 sequestration, environmental buffering and biodiversity maintenance. Dugongs are large marine mammals primarily found in the Indo-Pacific…
  pubmed Mohan M, Selvam PP, Stankovic M, Macreadie PI 等 2026 Jul 置信度 0.82
• Optimizing Cine Cardiac MRI: Technical Advances and Clinical Applications.
  Cine cardiac magnetic resonance imaging (MRI) is the gold standard for cardiac function assessment, offering exceptional spatial and temporal resolution in a non-invasive manner. Recently, there have been attempts to improve signal-to-noise ratio (SNR) and tem…
  pubmed Dehghani S, Rajabi A, Rahmati A, Omidi N 2026 Jul 置信度 0.82
• From cells to niches: Rewiring cardiovascular disease through spatial immunity.
  Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, yet their underlying immune mechanisms are still incompletely understood. A central limitation of current frameworks is that they largely conceptualize immune responses at the leve…
  pubmed Xie C, Shu X, Wu Y, Tian Y 2026 Jul 1 置信度 0.82
• Integrating AI Segmentation, Simulated Digital Twins, and Extended Reality into Medical Education: A Narrative Technical Review and Proof-of-Concept Case Study.
  Background/Objectives : Simulation digital twins (DT) models that integrate patient-specific imaging with artificial intelligence (AI)-based segmentation and extended reality (XR) technologies are rapidly increasing in relevance in personalized medicine. While…
  pubmed Kumar P, Siddarthan I, Keim CK, Cho DK 等 2026 Apr 3 置信度 0.82
• Integrative Computational Approaches to Prostate Cancer with Conditional Reprogramming and AI-Driven Precision Medicine.
  Prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC), presents therapeutic challenges rooted in adaptive lineage plasticity and neuroendocrine transdifferentiation. Conventional genome-based models fail to account for the diver…
  pubmed Fadiel A, Malpani P, Eichenbaum KD, Naftolin F 等 2026 Apr 15 置信度 0.82
• SkelPy: A graphic user interface-based approach for skeletonizing fungal networks.
  Traditional methods to quantify mycelial growth rely on destructive sampling to quantify biomass. Moreover, these approaches limit continuous observation and require a sufficient mass to measure. Recent work examines hyphal network traits by reconstructing the…
  pubmed Madrigal M, Moseley AJ, Moseley JC, Dowell JA 2026 Mar-Apr 置信度 0.82
• [Research progress on the acquisition technology of magnetocardiography].
  For certain cardiovascular diseases such as coronary artery disease and arrhythmia, electrocardiogram as a conventional cardiac function monitoring method has limitations such as insufficient resolution and unreliable accuracy in diagnosis. In contrast, magnet…
  pubmed Kang B, Dong M, Chang Y, Wang J 等 2026 Apr 25 置信度 0.82
• Single-cell insights into plant growth, adaptation, and evolution.
  The cellular heterogeneity associated with plant form and function is often overlooked in traditional bulk-tissue analyses. Emerging single-cell technologies provide new opportunities for dissecting this complexity at higher resolution. In this review, we summ…
  pubmed Wang F, Wang F, Wu Y, Pu L 等 2026 Aug 置信度 0.82
• Aortic fistulas: a pictorial review.
  Aortic fistulas are rare but life-threatening vascular abnormalities characterized by abnormal communication between the aorta and an adjacent structure secondary to weakening of the vessel wall, such as in the setting of atherosclerosis or prior surgical inte…
  pubmed Puello MP, Restrepo CS, Ocazionez D, Kirsch J 等 2026 Jul 1 置信度 0.82
• Pictorial review: a step-by-step guide to coronary CT angiography with photon-counting detector CT.
  Recent advances in CT technology have led to the advent of the photon-counting detector CT (PCD-CT). The technology has shown significant improvements in CT image quality with high spatial resolution, more accurate differentiation of coronary plaque components…
  pubmed Xie C, Clarke N, Kotronias R, Chan K 等 2026 Aug 1 置信度 0.82
• Flexible brain electronic sensors advance wearable brain-computer interface.
  The emerging field of wearable brain-computer interface (BCI) strives to achieve both high spatial and temporal resolution. The performance of flexible brain electronic sensor (FBES) has been validated across a variety of experimental settings, demonstrating t…
  pubmed Li J, Chen G, Li G, Xiao L 等 2025 Jul 2 置信度 0.82
• Head direction and the evolutionary origins of spatial representation.
  Spatial representations are a fundamental aspect of cognition. It remains largely unknown when and why the capacity to neurally represent space first evolved. In this opinion article, we argue that a strong candidate for the earliest such representation is the…
  pubmed Sayre ME, Narendra A, Heinze S, Barron AB 2026 Jun 置信度 0.82
• Graph Neural Networks in Neuroimaging: Current Status and Biostatistical Considerations for Clinical Deployment.
  Graph Neural Networks (GNNs) have emerged as a novel paradigm that enables scientists to model complex relational data in medical applications, offering unique advantages over traditional deep learning (DL) approaches for non-Euclidean domains. This paper prov…
  pubmed Kumar R, Sporn K, Waisberg E, Ong J 等 2026 Aug 置信度 0.82
• The changing landscape of gene expression analysis.
  Gene expression analysis has evolved substantially over the past 25 years, from early transcript surveys using expressed sequence tags and microarrays to RNA sequencing, and more recently to single-cell and spatial transcriptomics. These successive waves …
  pubmed Zhao Q, Shen S, Shim WJ, Palpant NJ 2026 Mar 1 置信度 0.82
• Predictors of sensitivity to immune therapies in classic Hodgkin lymphoma.
  Immune checkpoint blockade, particularly programmed cell death protein 1 inhibition, has redefined the management of classic Hodgkin lymphoma (cHL), achieving unprecedented efficacy in relapsed/refractory settings. Yet, durable benefit is not universal, becaus…
  pubmed Alibrahim MN, Carbone A, Gloghini A 2026 May 置信度 0.82
• Updates on tuberculosis imaging.
  Tuberculosis (TB) remains a leading infectious cause of morbidity and mortality worldwide, and major diagnostic and therapeutic challenges persist despite advances in microbiologic and molecular testing. Over the past decade, molecular imaging, especially with…
  pubmed Lawal IO, Ankrah AO, Abubakar S, Ndlovu H 等 2026 May 置信度 0.82
• Clonal analysis for understanding fate biases in developing embryos.
  Multipotent progenitors that appear phenotypically similar often differ in the range of cell types they generate, which is typically described as fate bias. Traditional bulk lineage-tracing approaches, such as Cre/Lox systems, established qualitative progenito…
  pubmed Isaev S, Adameyko I 2026 Aug 置信度 0.82
• ZScribbleSeg: A comprehensive segmentation framework with modeling of efficient annotation and maximization of scribble supervision.
  Curating fully annotated datasets for medical image segmentation is labor-intensive and expertise-demanding. To alleviate this problem, prior studies have explored scribble annotations for weakly supervised segmentation. Existing solutions mainly compute losse…
  pubmed Zhang K, Wang B, Zhou H, Zhuang X 2026 Jul 置信度 0.82
• Designing a Collaborative Immersive Visualization System for Radiation Treatment Planning Teams.
  We present a visualization design study of creating a collaborative virtual reality (VR) system for radiation treatment planning, with an emphasis on proton therapy. The goal is to support teams of dosimetrists, physicians, and medical physicists as they revie…
  pubmed Tran K, Broske M, Herman MG, Interrante V 等 2026 Jul 置信度 0.82