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The increasing size of electrophysiological datasets has heightened the need for quality metrics that automatically reject neurons whose activity was recorded with low sensitivity or specificity. One key approach estimates artifactual contamination by assuming…
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2026
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2024
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2025
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2026
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Blood flow to the brain is a sensitive marker of neuronal activity as well as of a number of diseases, including stroke, tumours and neurodegenerative conditions. Arterial spin labelling (ASL) is a non-invasive magnetic resonance imaging (MRI) method that can …
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2025
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2024
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Myocardial infarction remains a frequent cause of heart failure and mortality. Cell therapy has been shown promising in pre-clinical trials to regenerate the damaged tissue, but delivered cells may beat spontaneously and produce arrhythmias in the ventricles, …
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2025
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2026
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2025
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2025
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2026
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2025
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ABSTRACT Introduction and aim Understanding brain functions increasingly relies on a network-based perspective, emphasizing interactions across distributed regions. High-order cognitive functions, like language and executive processes, engage such networks rat…
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2026
置信度 0.74
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2026
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Abstract Rationale: Bupropion’s unique pharmacology as a dopaminergic and noradrenergic reuptake inhibitor distinguishes it from other antidepressants. Studies on a number of other antidepressants have demonstrated modulation of resting-state functional connec…
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2025
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2024
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2026
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Each person experiences the world through a unique conceptual lens, shaped by personal experiences, natural variations, or disease. These individual differences have remained largely inaccessible to cognitive neuroscience and clinical neurology, limiting the d…
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2025
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2025
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Recurrent neural networks (RNNs) transmit information over time through recurrent connections. In contrast, biological neural networks use many other temporal processing mechanisms. One of these mechanisms is the inter-neuron delays caused by varying axon prop…
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2024
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2024
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2025
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2025
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2024
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2026
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Functional compartmentalization in eukaryotic cells is essential for maintaining physiological processes. The development of systematic organelle proteomic techniques, such as Protein Correlation Profiling (PCP) and Localization of Organelle Proteins by Isotop…
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2024
置信度 0.74
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How organelles communicate stress to the nucleus to coordinate adaptive responses remains a fundamental question in cell biology. Here, we identify a non-canonical retrograde signaling pathway in which stalling-induced UFMylation of ER-associated ribosomes anc…
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2026
置信度 0.74
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2024
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Despite divergent behavioral and phenomenological profiles, both psychedelic states and reduced states of consciousness have been associated with a flattening of the brain's functional hierarchy. To address this apparent paradox, we developed a more specific d…
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2024
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2024
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2024
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2024
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2024
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Language is one of the most extensively studied lateralised cognitive functions in the human brain, predominantly relying on the left hemisphere in most individuals. However, the mechanisms by which a stable white matter architecture underpins individual langu…
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2025
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2025
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2024
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2024
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2026
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2025
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Determining the intricate structure and function of neural circuits requires the ability to precisely manipulate circuit activity. Two-photon holographic optogenetics has emerged as a powerful tool for achieving this via flexible excitation of user-defined neu…
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2025
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2026
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2025
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2024
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2026
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2024
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2025
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2024
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2024
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2024
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2024
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2024
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Our understanding of motor-related, macroscale brain processes has been significantly shaped by the description of the event-related desynchronization (ERD) and synchronization (ERS) phenomena in the mu and beta frequency bands prior to, during and following m…
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2024
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2024
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2024
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2024
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2024
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2026
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2024
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2024
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Abstract Introduction Neuroinflammation is a hallmark of various brain disorders, including neuropsychiatric conditions like major depressive disorder and schizophrenia. Increasing evidence suggests that both peripheral and central inflammation play a critical…
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2025
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2026
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2025
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2024
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2025
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2024
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Bone marrow mononuclear cells (BMMCs) are a heterogeneous pool of hematopoietic progenitors and mature immune cells that collectively sustain hematopoiesis and coordinate immune responses. The bone marrow serves not only as the primary site for blood cell prod…
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2025
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2024
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