-
Three-dimensional electron microscopy (3D EM) enables the quantitative analysis of cellular ultrastructure. However, large-scale segmentation of whole-cell volumes poses a significant challenge, especially in biologically diverse systems. Unlike medical and an…
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
Many microbial communities form multispecies biofilms where cells interact through diffusible molecules. In these biofilms, multiple interactions, often with opposing effects, occur simultaneously, yet we lack quantitative frameworks to predict how they combin…
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
A bstract The efficient coding hypothesis presents a compelling success story for theoretical and systems neu-roscience. It marshals a unifying idea, that neural codes can be understood as efficient encodings of natural stimuli, to explain phenomena from acros…
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
Abstract Cognitive deficits are common across many neurodevelopmental and psychiatric conditions, including those studied in the current set of PGC-CNV papers. How changes in regional gene expression across the cerebral cortex influence cognitive ability remai…
preprints
2025
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
The rapid growth in microscopy data volume, dimensionality, and diversity urgently calls for scalable and reproducible analysis frameworks. While efforts on the open OME-Zarr format have helped standardize the storage of large microscopy datasets, solutions fo…
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
An outstanding question in eukaryotic biology is the mechanistic connection between events occurring at (sub)cellular levels (time scales of milliseconds to minutes) to those at the tissue levels (tens of minutes to months). Deciphering such mechanisms require…
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
ABSTRACT Skeletal muscle displays remarkable plasticity, adapting its size and strength in response to mechanical loading, particularly, from exercise. This process, known as hypertrophy, is fundamental to athletic training and rehabilitation, but is challengi…
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
Maintenance of naïve pluripotency requires core transcription factors (TFs) like SOX2 and auxiliary TFs like NANOG, yet molecular mechanisms governing their intra-nuclear dynamics and DNA binding interactions remain unclear. Here, using high-density 3D single-…
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2026
置信度 0.74
-
Dengue is a mosquito-transmitted viral disease that has long defied control but now has a growing list of promising interventions becoming available. Major investments in these interventions are being made without a clear picture of the long-term implications …
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
Population receptive field (pRF) mapping is a fundamental technique for understanding retinotopic organization of the human visual system. Since its introduction in 2008, however, its scalability has been severely hindered by the computational bottleneck of it…
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
Abstract Pathology assessment is central to cancer diagnosis: a pathologist examines a whole-slide image and writes a report describing what they see. It remains an open question whether AI can do this end to end. Whole-slide images (WSIs) are gigapixel-scale,…
preprints
2026
置信度 0.74
-
ABSTRACT Astrocytes are increasingly recognized as active participants in sensory processing, but whether they show selective responses to stimulus features, analogous to neuronal receptive fields, is not yet established. To address this, we used two-photon ca…
preprints
2025
置信度 0.74
-
preprints
2026
置信度 0.74
-
Membrane fusion is ubiquitous in myriad biological processes, including presynaptic neurotransmitter release, myoblast fusion, virus entry, and fertilization 1–3 . It is often considered in the presence of fusogenic proteins, which mediate the fusion by pullin…
preprints
2026
置信度 0.74
-
Abstract Background: Zero-dose (ZD) children remain a critical public health concern, particularly in low- and lower-middle-income countries (LLMICs), where over 80% of the global ZD population resides, disproportionately concentrated among the most marginalis…
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
Single-cell omics has extended the biological interrogation of cell state from examining the expression of individual genes to unbiased profiling of tens of thousands of genes at once. However, extracting biological insights from such high-dimensional data rem…
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
Elucidating the neurobiological basis of neurodevelopmental and psychiatric conditions (NDPCs) remains challenging because brain alterations vary within diagnoses and overlap across them. Whether diverse alterations follow a systematic organization that may re…
preprints
2026
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
preprints
2025
置信度 0.74
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Spatially Resolved Transcriptomics (SRT) has revolutionized our understanding of gene expression within tissue microenvironments, yet accurately deciphering spatiotemporal structures-encompassing spatial domain identification, trajectory inference, and pseudo-…
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Biological systems inspire computing paradigms by autonomously regulating material and information flows through molecular interactions. While biomolecules such as enzymes and DNA have been harnessed for biocomputation, implementing complex logic operations re…
pubmed
Wu S, Tian L
2026
置信度 0.82
-
Tuberculosis (TB) is a highly contagious chronic infectious disease that, without timely intervention, can lead to severe health consequences or even death. Improper or incomplete treatment often induces the emergence of drug-resistant TB (DR-TB), which greatl…
europepmc
2026
置信度 0.80
-
Despite extensive efforts to regulate water activity in hydrogel electrolytes for aqueous zinc-ion batteries (AZIBs), current strategies are insufficient to impose spatial constraints on water molecules and prevent the self-assembly of bulk water networks. Her…
pubmed
Liao Y, Chen Z, Tao L, Tang Y 等
2026
置信度 0.82
-
Optical reservoir computing (RC) is a hardware-efficient paradigm that leverages intrinsic optical properties to process information. This paper proposes a diffractive optoelectronic-reservoir computing (DOE-RC) architecture. The architecture utilizes an optoe…
pubmed
Chen Z, Liu Z, Wang L, Ma R 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
In the face of increasingly sophisticated cyber threats in an interconnected world, the need for scalable, intelligent, real-time cybersecurity solutions is intensifying. While traditional deep learning, such as convolutional neural networks (CNNs) and recurre…
pubmed
Abdel-Aty AH, Farsi M, Hafez M, Voon BW
2026
置信度 0.82
-
Metasurfaces exploit subwavelength scattering elements to manipulate light with a level of flexibility that is difficult to achieve using conventional optical platforms, making them promising building blocks for next-generation photonic systems. Yet the increa…
pubmed
Wang Y, Wang Z, Li K, Liang H 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
Time-delay embedding is a prominent method in neural networks to improve the performance of predictions of the dynamics of nonlinear systems. Applied to reservoir computing, a recurrent machine learning model in which the output weights are trained only, an im…
pubmed
Bartelmei A, Zier M, Schumacher J, Sinzinger S
2026
置信度 0.82
-
Abstract Microbial fuel cells (MFCs) convert the chemical energy stored in organic substrates into electrical energy through the metabolic activity of electroactive microorganisms. Their performance is governed by coupled biological, electrochemical, and mass-…
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Phenotypic plasticity enables prey species to develop inducible defences in response to predation risk, significantly influencing predator-prey interactions. In this study, we propose a nonlinear predator-prey model in which prey exhibit inducible defense mech…
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Event-related EEG activity is widely investigated to characterize brain functions. Traditional analyses rely on heavy pre-processing and strong a priori assumptions, which limit reproducibility and may obscure task-relevant neural activity. This study aims to …
pubmed
Borra D, Magosso E
2026
置信度 0.82
-
The advent of microscopic-resolution spatial transcriptomics ( μ ST ) enables the mapping of tissue complexity at subcellular resolution. However, the massive increase in data volume introduces a critical "memory wall," significantly limiting the applica…
pubmed
Jiang T, Zhang S, Chen X, Xiao X 等
2026
置信度 0.82
-
ABSTRACT Single-cell spatial transcriptomics can connect molecular cell states with tissue morphology, but this promise depends on accurate registration to histopathology. In serial sections, however, tissue borders often differ because of sectioning artifacts…
europepmc
2026
置信度 0.80
-
Conventional photonic time-delay reservoir computing (TDRC) with a single delay is constrained by a fixed ring virtual node topology, limiting its adaptability across tasks with different dynamical requirements. Here, we propose and experimentally demonstrate …
pubmed
Zhang L, Zeng W, Li S, Pan W 等
2026
置信度 0.82
-
Text-conditioned generation of volumetric computed tomography (CT) from radiology reports is limited by the absence of explicit spatial information. Retrieval-augmented methods provide anatomical guidance, but existing approaches rely on a single nearest-neigh…
pubmed
Hou J, Wang S, Zhang Y, Liu J 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Transfer-based black-box adversarial attacks provide a practical means to evaluate the robustness of deep neural networks under restricted access to target models. However, existing approaches suffer from severe performance degradation in cross-architecture sc…
pubmed
Lu Q, Zong L, Liu F, Tang M 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Energy-efficient coordination of robotic swarms requires effective integration of task scheduling, motion planning, and communication management, particularly in resource-constrained environments where computation and wireless communication compete for limited…
pubmed
Ijaz A, Haghbayan H, Nigussie E, Plosila J
2026
置信度 0.82