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• Multi-omics-guided metabolic engineering of Limosilactobacillus reuteri for high-level 3-hydroxypropionaldehyde production from glucose
  europepmc 2026 置信度 0.80
• Recent advances in biosynthesis, regulation, and metabolic engineering of flavonoids.
  europepmc 2025 置信度 0.80
• Precise biosynthesis of β-1,2-glucan from cellulosic materials by in vitro metabolic engineering.
  europepmc 2026 置信度 0.80
• Combination of adaptive laboratory evolution and metabolic engineering on Vibrio natriegens for efficient production of 3-hydroxypropionic acid from ethanol.
  europepmc 2026 置信度 0.80
• Systematic Metabolic Engineering of <i>Escherichia coli</i> for High-Level Production of 5-Aminolevulinic Acid.
  europepmc 2026 置信度 0.80
• Reconstructing the hydrogenobyrinic acid synthetic toolkit by combining cell-free systems and metabolic engineering.
  europepmc 2026 置信度 0.80
• Modular metabolic engineering of Yarrowia lipolytica and semi-rational design of CYP716A520 for enhanced betulinic acid biosynthesis.
  europepmc 2026 置信度 0.80
• Xylose metabolic engineering of Issatchenkia orientalis for 3-hydroxypropionic acid production from cellulosic hydrolysate without nutrient supplementation.
  europepmc 2026 置信度 0.80
• Recent advances in metabolic engineering of purple non‑sulfur photosynthetic bacteria for enhanced biohydrogen production.
  europepmc 2026 置信度 0.80
• Sustainable Production of Ginsenosides: Advances in Biosynthesis and Metabolic Engineering.
  europepmc 2025 置信度 0.80
• Systematic metabolic engineering of an industrial Penicillium citrinum for one-step pravastatin production.
  europepmc 2026 置信度 0.80
• Metabolic engineering of Phaeodactylum tricornutum for heterologous production of the plant triterpenoid friedelin.
  europepmc 2025 置信度 0.80
• Metabolic engineering of microorganisms for tailor-made biopolymer production: A review.
  europepmc 2025 置信度 0.80
• Systematic Metabolic Engineering and Fermentation Optimization of <i>Yarrowia lipolytica</i> for High-Yield Production of Scutellarin.
  europepmc 2026 置信度 0.80
• Recent advances in metabolic engineering of Escherichia coli for riboflavin biosynthesis.
  europepmc 2025 置信度 0.80
• Metabolic engineering of a plasmid-free, non-auxotrophic Escherichia coli for efficient glycolate production.
  europepmc 2026 置信度 0.80
• High-level prodigiosin production in <i>Pseudomonas putida</i> enabled by combinatorial metabolic engineering.
  europepmc 2026 置信度 0.80
• TRIAD: Trans‑disciplinary Inference, Active Dynamics and Ontology (Version 6.2.dev — Public Monograph)
  TRIAD 6.2‑dev Monograph: A Formal Ontology of Coherence, Trauma Therapy, and Safe AI — with Seven Architectural Invariants, Information‑Valence Gate, and Social Validation Author: Valeriia Zaiats (Валерия Заяц) ORCID: 0009-0002-6891-9227 Licence: CC BY‑NC‑ND 4…
  datacite Zaiats, Valeriia 2026 置信度 0.66 Active InferenceFree Energy PrincipleComputational PsychiatryAI SafetyAI Alignment
• TRIAD: Trans‑disciplinary Inference, Active Dynamics and Ontology (Version 6.2.dev — Public Monograph)
  TRIAD 6.2‑dev Monograph: A Formal Ontology of Coherence, Trauma Therapy, and Safe AI — with Seven Architectural Invariants, Information‑Valence Gate, and Social Validation Author: Valeriia Zaiats (Валерия Заяц) ORCID: 0009-0002-6891-9227 Licence: CC BY‑NC‑ND 4…
  datacite Zaiats, Valeriia 2026 置信度 0.66 Active InferenceFree Energy PrincipleComputational PsychiatryAI SafetyAI Alignment
• The Economic and Civilizational Valuation of Cryptographically Tethered Audio Portfolios within the CollectiveOS Architecture
  The Economic and Civilizational Valuation of Cryptographically Tethered Audio Portfolios within the CollectiveOS Architecture The valuation of digital audio assets has historically been bound to the mechanics of the "Extractive Age," a paradigm that relies on …
  datacite Brewer, Mark Anthony 2026 置信度 0.66
• The Economic and Civilizational Valuation of Cryptographically Tethered Audio Portfolios within the CollectiveOS Architecture
  The Economic and Civilizational Valuation of Cryptographically Tethered Audio Portfolios within the CollectiveOS Architecture The valuation of digital audio assets has historically been bound to the mechanics of the "Extractive Age," a paradigm that relies on …
  datacite Brewer, Mark Anthony 2026 置信度 0.66
• Aegis: A Bio-Inspired, Zero-Trust Architecture for Homeostatic AI Agent Governance
  Abstract: Current AI governance frameworks predominantly treat safety as an external perimeter, relying on prompt guardrails and post-hoc filters. While functional for static models, this paradigm fails when applied to Autonomous Agents capable of continuous r…
  datacite He, Muchen 2026 置信度 0.66 Autonomous Agents;Metabolic ConstraintsArtificial IntelligenceBio-Inspired AIAI Governance
• Aegis: A Bio-Inspired, Zero-Trust Architecture for Homeostatic AI Agent Governance
  Abstract: Current AI governance frameworks predominantly treat safety as an external perimeter, relying on prompt guardrails and post-hoc filters. While functional for static models, this paradigm fails when applied to Autonomous Agents capable of continuous r…
  datacite He, Muchen 2026 置信度 0.66 Autonomous Agents;Metabolic ConstraintsArtificial IntelligenceBio-Inspired AIAI Governance
• Aegis Cortex: A Bio-Inspired, Zero-Trust Architecture for Homeostatic AI Agent Governance
  Abstract: Current AI governance frameworks predominantly treat safety as an external perimeter, relying on prompt guardrails and post-hoc filters. While functional for static models, this paradigm fails when applied to Autonomous Agents capable of continuous r…
  datacite He, Muchen 2026 置信度 0.66 Autonomous Agents;Metabolic ConstraintsArtificial IntelligenceBio-Inspired AIAI Governance
• Emerging Therapies for Inborn Errors of Metabolism: Enzyme Replacement, Gene Therapy, Genome Editing
  Abstract Inborn Errors of Metabolism (IEMs) are a heterogeneous collection of inherited genetic illnesses resulting from abnormalities in enzymes, transport proteins, or cofactors involved in important metabolic pathways. These deficiencies interfere with norm…
  datacite Nebedum Emilia Nwakaego, Mbah Gertrude, Deborah Chinonso, Osimiri Eugene Chika 等 2026 置信度 0.66 Inborn Abnormalities of Metabolism; Enzyme Replacement Therapy; Gene Therapy; Genome Editing; CRISPR-Cas9 Lysosomal Storage Problems; Precision Medicine
• Emerging Therapies for Inborn Errors of Metabolism: Enzyme Replacement, Gene Therapy, Genome Editing
  Abstract Inborn Errors of Metabolism (IEMs) are a heterogeneous collection of inherited genetic illnesses resulting from abnormalities in enzymes, transport proteins, or cofactors involved in important metabolic pathways. These deficiencies interfere with norm…
  datacite Nebedum Emilia Nwakaego, Mbah Gertrude, Deborah Chinonso, Osimiri Eugene Chika 等 2026 置信度 0.66 Inborn Abnormalities of Metabolism; Enzyme Replacement Therapy; Gene Therapy; Genome Editing; CRISPR-Cas9 Lysosomal Storage Problems; Precision Medicine
• Engineering alternative bacterial platforms for sustainable bioproduction
  Modern biotechnology relies on a handful of well-studied microbial species cultivated on sugar-derived feedstocks. Although highly successful, their dependence on agricultural resources, sensitivity to contamination, and limited tolerance to unconventional con…
  datacite Bernal Cabas, Margarita, Billerbeck, Sonja 2026 置信度 0.66 Non-model microorganismsMicrobial platform maturitysustainable biotechnologyalternative feedstocksmetabolic diversity
• Engineering alternative bacterial platforms for sustainable bioproduction
  Modern biotechnology relies on a handful of well-studied microbial species cultivated on sugar-derived feedstocks. Although highly successful, their dependence on agricultural resources, sensitivity to contamination, and limited tolerance to unconventional con…
  datacite Bernal Cabas, Margarita, Billerbeck, Sonja 2026 置信度 0.66 Non-model microorganismsMicrobial platform maturitysustainable biotechnologyalternative feedstocksmetabolic diversity
• Cartilage and Osteochondral Organoids for Knee Osteoarthritis Research
  This project will systematically review and map the use of in-vitro cartilage and osteochondral organoid or organoid-like platforms in knee osteoarthritis (OA) research. The review is motivated by the need for human-relevant and mechanistically informative new…
  datacite MBN 2026 置信度 0.66 Medicine and Health SciencesLife SciencesBiotechnologyEngineeringBiomedical Engineering and Bioengineering
• The Consensus Protocol: A Strategic Framework for Causal Cancer Eradication Based on SRE Dynamics
  Traditional oncology operates entirely within the "Physical Rendering Layer," utilizing brute-force chemical or radiative entities to destroy biological matter, which invariably introduces devastating systemic toxicity. Within the framework of Status-Relationa…
  datacite Lu, Yue 2026 置信度 0.66 SRE DynamicsCausal TopologyCancer EradicationInformation PhysicsLogic Cancellation
• A superfamily of bioactive proteins from fungi - are these secondary metabolites?
  Abstract Background Since decades, fungi are leveraged in biotechnology to produce high-value compounds used in multiple economic sectors. Strain and process optimisation is based on a comprehensive understanding of the production organism on the cellular and …
  datacite Claudia Feurstein, Lisa Bachmann, Lena Heber, Birgit Dobbert 等 2026 置信度 0.66 BiochemistryMicrobiologyGeneticsMolecular BiologyPharmacology
• A superfamily of bioactive proteins from fungi - are these secondary metabolites?
  Abstract Background Since decades, fungi are leveraged in biotechnology to produce high-value compounds used in multiple economic sectors. Strain and process optimisation is based on a comprehensive understanding of the production organism on the cellular and …
  datacite Claudia Feurstein, Lisa Bachmann, Lena Heber, Birgit Dobbert 等 2026 置信度 0.66 BiochemistryMicrobiologyGeneticsMolecular BiologyPharmacology
• Stones Law Esoteric Language: Disparate Proofs ;Pharmacodynamics, Meteorology with a SDK Template
  Published July 9, 2026 Stones Law Proofs Authors/Architect: Stone, Travis Raymond-Charlie Description Math from Travis RC Stone as represented by, S=MTF expression for the unified field theory as a utility, and as an example of the solution presented by Stone …
  datacite Stone, Travis Raymond-Charlie 2026 置信度 0.66
• Consciousness as RAM Architecture: Qualia, Emergence of the Ego and Evolutionary Decoupling
  Note / Remarque : ⚠️ Please note that the full text of this article is published exclusively in English. ⚠️ Veuillez noter que le texte complet de cet article est publié exclusivement en anglais. 🇬🇧 English Description Abstract Consciousness is generally mod…
  datacite Dufour, Jonathan 2026 置信度 0.66 ConsciousnessConsciousness MonitorsConsciousness/classificationConsciousness/physiologyConsciousness/ethics
• Consciousness as RAM Architecture: Qualia, Emergence of the Ego and Evolutionary Decoupling
  Note / Remarque : ⚠️ Please note that the full text of this article is published exclusively in English. ⚠️ Veuillez noter que le texte complet de cet article est publié exclusivement en anglais. 🇬🇧 English Description Abstract Consciousness is generally mod…
  datacite Dufour, Jonathan 2026 置信度 0.66 ConsciousnessConsciousness MonitorsConsciousness/classificationConsciousness/physiologyConsciousness/ethics
• Electroweak Symmetry as Recursive Phase Alignment
  Electroweak symmetry in conventional physics is expressed through the SU(2) × U(1)gauge group, spontaneous symmetry breaking, and the Higgs mechanism. The electroweak standard model provides highly precise quantitative predictions confirmed toparts per million…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Electroweak Symmetry as Recursive Phase Alignment
  Electroweak symmetry in conventional physics is expressed through the SU(2) × U(1)gauge group, spontaneous symmetry breaking, and the Higgs mechanism. The electroweak standard model provides highly precise quantitative predictions confirmed toparts per million…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Dark Energy as Residual Pressure Gradient Drift
  The ΛCDM model provides the quantitative description of late-universe acceleration;this paper does not challenge its results within their domain of validity. Instead, itdevelops the geometric substrate from which dark energy emerges in the Cohesion UnifiedFiel…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Dark Energy as Residual Pressure Gradient Drift
  The ΛCDM model provides the quantitative description of late-universe acceleration;this paper does not challenge its results within their domain of validity. Instead, itdevelops the geometric substrate from which dark energy emerges in the Cohesion UnifiedFiel…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Black Holes as Recursion Collapse Pressure Wells
  General relativity’s Schwarzschild and Kerr solutions provide the quantitative description of black hole geometry confirmed by LIGO gravitational wave detections and EventHorizon Telescope imaging; this paper does not challenge those results within theirdomain…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Black Holes as Recursion Collapse Pressure Wells
  General relativity’s Schwarzschild and Kerr solutions provide the quantitative description of black hole geometry confirmed by LIGO gravitational wave detections and EventHorizon Telescope imaging; this paper does not challenge those results within theirdomain…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• The c-bit
  The Cohesion Unified Field Theory identifies the electron as a trapped bipolar (n = 2)recursion whose two torsion phases constitute a deterministic geometric binary. Thispaper defines the c-bit — the coherence bit — as the minimal computational unit derivedfro…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• The c-bit
  The Cohesion Unified Field Theory identifies the electron as a trapped bipolar (n = 2)recursion whose two torsion phases constitute a deterministic geometric binary. Thispaper defines the c-bit — the coherence bit — as the minimal computational unit derivedfro…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Nuclear Binding Energies in the Cohesion Unified Field Theory
  Nuclear binding in the Cohesion Unified Field Theory arises from two interactinggeometric mechanisms: (1) n = 2 collapse pressure, the short-range bipolar recursionthat drives nucleons together, and (2) torsion density compression, the curvature-drivenresistan…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Nuclear Binding Energies in the Cohesion Unified Field Theory
  Nuclear binding in the Cohesion Unified Field Theory arises from two interactinggeometric mechanisms: (1) n = 2 collapse pressure, the short-range bipolar recursionthat drives nucleons together, and (2) torsion density compression, the curvature-drivenresistan…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Scale Hierarchy and the Multiverse as Nested Recursion Domains
  The scale hierarchy of the Cohesion Unified Field Theory is not a speculative additionto the framework — it follows directly from the foundational axiom. If the observableuniverse is under pressure from the next higher scale, then our universe is a boundedrecu…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Scale Hierarchy and the Multiverse as Nested Recursion Domains
  The scale hierarchy of the Cohesion Unified Field Theory is not a speculative additionto the framework — it follows directly from the foundational axiom. If the observableuniverse is under pressure from the next higher scale, then our universe is a boundedrecu…
  datacite Gilbert, Dexter 2026 置信度 0.66 PhysicsPhysicsMathematical physicsLaser physicsPhysics/instrumentation
• Seed Storage Technologies
  Seeds are living packages of the future each one carrying the genetic blueprint of a plant, suspended in a state of low metabolic activity until conditions favor germination. This dormancy is not passive; it is a finely regulated biological state that can be e…
  datacite Dr. Ashok Kumar, Dr. Vinod Kumar and Dr. Sanjeev Kumar Yadav 2026 置信度 0.66
• Seed Storage Technologies
  Seeds are living packages of the future each one carrying the genetic blueprint of a plant, suspended in a state of low metabolic activity until conditions favor germination. This dormancy is not passive; it is a finely regulated biological state that can be e…
  datacite Dr. Ashok Kumar, Dr. Vinod Kumar and Dr. Sanjeev Kumar Yadav 2026 置信度 0.66
• In Defense of the Leaders
  IN DEFENSE OF THE LEADERS: The Jolly Triad Herd Management Manual An unsolicited strategic audit and high-utility operational briefing structured for the executive and governing classes. Applying the unyielding laws of macro-scale engineering, evolutionary bio…
  datacite Vaden, Denis 2026 置信度 0.66
• In Defense of the Leaders
  IN DEFENSE OF THE LEADERS: The Jolly Triad Herd Management Manual An unsolicited strategic audit and high-utility operational briefing structured for the executive and governing classes. Applying the unyielding laws of macro-scale engineering, evolutionary bio…
  datacite Vaden, Denis 2026 置信度 0.66
• Systems-Level and Flux Analyses Reveal Metabolic Antagonism as a Primary Barrier to Oilseed Design
  Plant oils are energy-dense, have wide-ranging applications, and command a market in the tens of billions of dollars, with demand forecasted to greatly outpace future supply. Oilseeds that could accumulate unusual fatty acids would be an indispensable source o…
  datacite Lingwan, Maneesh, Zhou, Jiahong, Nascimento, Jose Roberto Da Silva, Roth, Mary R. 等 2026 置信度 0.66 Camelina sativaSunesonMedium-chain fatty acidsCupheaseed oil
• Systems-Level and Flux Analyses Reveal Metabolic Antagonism as a Primary Barrier to Oilseed Design
  Plant oils are energy-dense, have wide-ranging applications, and command a market in the tens of billions of dollars, with demand forecasted to greatly outpace future supply. Oilseeds that could accumulate unusual fatty acids would be an indispensable source o…
  datacite Lingwan, Maneesh, Zhou, Jiahong, Nascimento, Jose Roberto Da Silva, Roth, Mary R. 等 2026 置信度 0.66 Camelina sativaSunesonMedium-chain fatty acidsCupheaseed oil
• From Genome to Monitor: Integrating Multi-Omics into Patient-Specific Anesthesia Digital Twins
  Journal Submission Metadata & Descriptions When uploading your manuscript to a journal submission portal (e.g., Editorial Manager, ScholarOne), you will be prompted to provide short descriptions, highlights, and a summary of how the paper fits the journal's sc…
  datacite Ayash Ashraf, Munazah Bashir, Danish Ishfaq 2026 置信度 0.66
• From Genome to Monitor: Integrating Multi-Omics into Patient-Specific Anesthesia Digital Twins
  Journal Submission Metadata & Descriptions When uploading your manuscript to a journal submission portal (e.g., Editorial Manager, ScholarOne), you will be prompted to provide short descriptions, highlights, and a summary of how the paper fits the journal's sc…
  datacite Ayash Ashraf, Munazah Bashir, Danish Ishfaq 2026 置信度 0.66
• Real-Time Medical Diagnostics: Substrate Field-Geometry
  Traditional medical diagnostics are fundamentally chemical in nature: they sample discrete molecular markers from blood, tissue, or urine and infer biological state from those discrete, time-lagged snapshots. Unified Substrate Theory (UST) identifies this meth…
  datacite Lee, Dustin 2026 置信度 0.66 Sjogren's syndromeAQP5Tight JunctionsEpithelial polarityExtracellular Matrix
• Foam control in biotechnological processes - challenges and opportunities
  Foam formation is a massive challenge in submerged aerated bioprocesses, e.g., in beer fermentation. While the use of antifoam may easily overcome foaming at laboratory scale, it is often an unattractive solution since the challenge remains in future upscaling…
  datacite Tiso, Till, Demling, Philipp, Karmainski, Tobias, Oraby, Amira 等 2024 置信度 0.66 AerationBiosurfactantsFermentationFoam fractionationGlycolipids
• CARDIAC DISEASE PREDICTION USING MACHINE LEARNING AND DEEP LEARNING:A COMPREHENSIVE MULTI-MODEL CLINICAL EVALUATION WITH RECALL OPTIMIZATION
  Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, claiming approximately 17.9 million deaths annually. Early detection of high-risk individuals is critical to reducing mortality rates, yet this remains challenging due to the multi…
  datacite Ms. Shreyaben Pareshkumar, Bhatt, Dr. Kusum Lata, Aggarwal 2026 置信度 0.66 cardiac disease prediction, machine learning, deep learning, recall optimisation, SMOTE, Extra Trees, XGBoost, clinical feature engineering, class imbalance, risk stratification.
• CARDIAC DISEASE PREDICTION USING MACHINE LEARNING AND DEEP LEARNING:A COMPREHENSIVE MULTI-MODEL CLINICAL EVALUATION WITH RECALL OPTIMIZATION
  Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, claiming approximately 17.9 million deaths annually. Early detection of high-risk individuals is critical to reducing mortality rates, yet this remains challenging due to the multi…
  datacite Ms. Shreyaben Pareshkumar, Bhatt, Dr. Kusum Lata, Aggarwal 2026 置信度 0.66 cardiac disease prediction, machine learning, deep learning, recall optimisation, SMOTE, Extra Trees, XGBoost, clinical feature engineering, class imbalance, risk stratification.
• gaodandan-ai/cg_sequencing: v0.3.1 — Regulatory–Metabolic Integration MVP
  This is the first public release of Cgl Regulation Explorer, an interactive regulatory–metabolic analysis platform for Corynebacterium glutamicum. The platform integrates transcriptional regulatory networks, RF-based edge confidence scoring, genome-scale metab…
  datacite Komorebi 2026 置信度 0.66
• gaodandan-ai/cg_sequencing: v0.3.1 — Regulatory–Metabolic Integration MVP
  This is the first public release of Cgl Regulation Explorer, an interactive regulatory–metabolic analysis platform for Corynebacterium glutamicum. The platform integrates transcriptional regulatory networks, RF-based edge confidence scoring, genome-scale metab…
  datacite Komorebi 2026 置信度 0.66
• Exploring the plasticity of lignification via ectopic expression of exogeneous CoA ligases in planta
  Lignin is a major component of plant secondary cell walls and is essential for structural support, vascular integrity, and water transport. However, the complex structure of lignin also contributes significantly to biomass recalcitrance, limiting the efficienc…
  datacite Sun, Zimou 2026 置信度 0.66
• Constraint–Flow Theory (CFL): A Scale-Invariant Theory of Everything
  This paper presents Constraint–Flow Theory (CFL) as a unified, scale-invariant framework describing how all persistent systems form, stabilize, and decay. CFL asserts that everything that exists is energy in motion, and that energy must flow through constraint…
  datacite Skenandore, Jed 2026 置信度 0.66 System thinking
• Constraint–Flow Theory (CFL): A Scale-Invariant Theory of Everything
  This paper presents Constraint–Flow Theory (CFL) as a unified, scale-invariant framework describing how all persistent systems form, stabilize, and decay. CFL asserts that everything that exists is energy in motion, and that energy must flow through constraint…
  datacite Skenandore, Jed 2026 置信度 0.66 System thinking
• Interactions of rumen-protected histidine and dietary starch in low-protein diets with adequate lysine and methionine: effects on lactational performance and nitrogen utilization in dairy cows
  The objective of this study was to investigate interactions between dietary starch amount and rumen-protected His (RPHis) on nutrient utilization, milk production, N partitioning, and plasma AA and metabolites concentrations in dairy cows fed MP-deficient diet…
  datacite Peng, Rong, Schudel, A., Ma, Xiaoqi, Blanco, M.B. 等 2026 置信度 0.66
• Genomic signatures highlight stress-response evasion and translational tuning as key drivers of Escherichia coli adaptation to fluorinated tryptophans
  Fluorinated amino acids profoundly perturb cellular physiology because they enter the proteome while differing from their natural counterparts in subtle but functionally important ways. Here we investigated how Escherichia coli adapts to the biosynthesis and p…
  datacite Treiber-Kleinke, Christin, Göller, Jana Madeleine, Liba, Justin, Wong, Michael Chun-Hin 等 2026 置信度 0.66
• ERA-CoBioTech 1: Biotechnologische nachhaltige Produktion von Indol; Teilvorhaben 1: Metabolic Engineering, Stammkonstruktion und omics-Analysen : Schlussbericht zum Vorhaben : Laufzeit: 01.10.2018-31.03.2022
  https://creativecommons.org/licenses/by-nd/3.0/de/
  datacite Unknown 2022 置信度 0.66 BiologyChemical and environmental engineering
• Biodiesel aus Lignocellulose durch Metabolic Engineering eines Basidiomyceten : Schlussbericht zum Vorhaben : Laufzeit: 01.02.2015 bis 31.04.2018
  Illustrationen, Diagramme
  datacite Dietz, David, Wandrey, Maren 2020 置信度 0.66 BiodieselUstilago zeaeFettsäureesterLignocelluloseProzessentwicklung (Technik)
• DeYeastLibrary - ERA-IB4: DeYeastLibrary-Designer, Hefe-Stamm Sammlung optimiert für Metabolic Engineering Anwendungen; Teilprojekt 2 : Schlussbericht - Erfolgskontrollbericht (nach Nr. 3.2b BNBest-BMBF 98) : Laufzeit des Vorhabens: 01.06.2017 bis 31.12.2017
  Illustrationen, Diagramme
  datacite Kötter, Peter, Meyer, Britta 2018 置信度 0.66 HefegewinnungBiotechnologieChemical and environmental engineering
• ERA-IB 4: DeYeastLibrary-Designer Hefe-Stamm Sammlung optimiert für Metabolic Engineering Anwendungen; Teilprojekt 1 : Schlussbericht, kurzer inhaltlicher Bericht nach BNBest-BMBF98
  datacite Patil, Kiran Raosaheb 2019 置信度 0.66 Saccharomyces cerevisiaeDicarbonsäurenHefegewinnungStoffwechselBiotechnologie
• Verbundvorhaben: ERA-IB 3: Wissensbasierte Konstruktion verbesserter Clostridien-Stämme zur Etablierung produktiver Fermentationen (REACTIF), Teilvorhaben 1: Metabolic Engineering : Schlussbericht zum Vorhaben : Laufzeit: 01.05.2013 bis 31.10.2016, Monat der Erstellung: 02/2017
  Illustrationen, Diagramme
  datacite Unknown 2017 置信度 0.66 FermentationClostridiumBiologyMikrobiologie
• Schlussbericht zum Vorhaben ERA-IB Verbundprojekt: Metabolisches und Enzym Engineering für eine biotechnologische Produktion von partiell azetylierte Chitosane - ChitoBioEngineering; TP 2 im Gesamtvorhaben: Metabolic and enzyme engineering for the biotechnological production of partially acetylated chitosans : Laufzeit: 01.03.2011-30.06.2015
  datacite Unknown 2015 置信度 0.66 ChitosanderivateDesacetylierungFermentationBiologyKohlenhydrate (Biochemie)
• Maßgeschneiderte Inhaltsstoffe 2 - Verbundvorhaben: "Metabolic Engineering von Bäckerhefe (Saccharomyces cerevisiae) zur Herstellung von langkettigem Bio-Polyphosphat (MeY4bioPP) - Teilprojekt A"
  https://creativecommons.org/licenses/by-nd/3.0/de/
  datacite Blank, Lars Mathias, Demling, Philipp, Fees, Jana 2023 置信度 0.66 BiologyChemical and environmental engineering
• Verbundprojekt: GABI-Kanada (CGAT): "YelLowSin" - Functional genomic approaches for the development of yellow-seeded, low sinapine oilseed rape (Canola, Brassica napus), Teilprojekt B: Metabolic engineering of sinapate ester metabolism and indentification of candidate genes for molecular breeding : Ergebnisse eines Forschungsvorhabens im BMBF-Programm BIOLOGIE ; Laufzeit: 01.01.2006 bis 31.10.2009
  graph. Darst.
  datacite Leibniz-Institut für Pflanzenbiochemie, Halle (Saale) 2010 置信度 0.66 RapszüchtungBiochemie: AllgemeinesBiologyPflanzenphysiologieChemistry
• GEO-SeqGuider
  GEO-SeqGuider is a genomic language model developed to predict CRISPR regulatory activity in Pseudomonas putida. Built on the Llama architecture, the model was trained through a two-stage process that first incorporates large-scale bacterial genomic sequences …
  datacite lilei 2026 置信度 0.66
• GEO-SeqGuider
  GEO-SeqGuider is a genomic language model developed to predict CRISPR regulatory activity in Pseudomonas putida. Built on the Llama architecture, the model was trained through a two-stage process that first incorporates large-scale bacterial genomic sequences …
  datacite lilei 2026 置信度 0.66
• Verbundprojekt: Integrierte Phänotyp-Genotyp Plattform (IPG) - Weiterentwicklung der biotechnologischen Stammentwicklung durch Identifizierung unbekannter Metabolic Engineering Targets, Teilprojekt B : Veröffentlichung der Ergebnisse von Forschungsvorhaben im BMBF-Programm ; Projektlaufzeit: 01.12.2010 bis 30.11.2013
  graph. Darst.
  datacite Unknown 2013 置信度 0.66 BiologyChemical and environmental engineeringHorticulture
• Integrierte Phänotyp-Genotyp Plattform (IPG) : Teilprojekt 1: Weiterentwicklung der biotechnologischen Stammentwicklung durch Identifizierung unbekannter Metabolic Engineering Targets ; Cluster ; Laufzeit: 01.12.2010 - 31.03.2014
  graph. Darst.
  datacite Evonik Industries AG 2014 置信度 0.66 Chemical and environmental engineering
• ERA-IB Verbundprojekt: Produktion von Tacrolimus und entsprechenden Immunsupressiva in stabiler Fermentation - IMMUNOTEC; Teilprojekt: Konstruieren eines Nebenprodukt-freien Hochproduzenten mittels molekularer Genetik und Metabolic Engineering : Schlussbericht : Laufzeit des Vorhabens: 01.03.2011-30.09.2014
  datacite Unknown 2015 置信度 0.66 MedicineBiology
• Isolierung neuer Glycosyltransferasen für das Metabolic Engineering von mikrobiellen Fermentationsstämmen für die Herstellung komplexer Milchzucker für den Einsatz in funktionellen Nahrungsmitteln : Abschlussbericht
  Illustrationen, Diagramme
  datacite Jennewein, Stefan, Wartenbrg, Dirk, Parschat, Katja 2016 置信度 0.66 EnzymaktivitätLactoseGlycosyltransferasenBiologyLebensmitteltechnologie
• Thousands of Entangled Cellular Metabolic Networks Solved by Quantum Computers... First Demonstration of the QSVT Algorithm
  • Published on bioRxiv, presenting the first quantum algorithm to dramatically accelerate Flux Balance Analysis (FBA), a core technique in cellular metabolism research. • Overcomes the computational limits of existing classical computing by introducing the Qua…
  datacite inquantio 2026 置信度 0.66 quantum biology
• Thousands of Entangled Cellular Metabolic Networks Solved by Quantum Computers... First Demonstration of the QSVT Algorithm
  • Published on bioRxiv, presenting the first quantum algorithm to dramatically accelerate Flux Balance Analysis (FBA), a core technique in cellular metabolism research. • Overcomes the computational limits of existing classical computing by introducing the Qua…
  datacite inquantio 2026 置信度 0.66 quantum biology
• Reproducibility package for: "When does intravenous oxygen help? A physiological simulation of oxygen microbubble infusion across two regimes of critical oxygen economy: the difficult airway and cardiac arrest."
  # Reproducibility package: intravenous oxygen microbubbles across two oxygen economiesPhysiological simulation code, generated data and figures accompanying the manuscript"When does intravenous oxygen help? A physiological simulation of oxygen microbubbleinfus…
  datacite Gomes Mendes, Henrique 2026 置信度 0.66
• Bioeconomía y el Valor del Residuo
  This book presents a technical and conceptual analysis of residential bioeconomy systems, focusing on the transformation of organic and inorganic waste streams into valuable resources within domestic and urban environments. It reframes waste not as a residual …
  datacite Hernandez García, Oscar Adrián 2026 置信度 0.66 PRMSMetabolic ArchitectureSustainable ArchitetureEnergy SystemsRenewable Energy
• Bioeconomía y el Valor del Residuo
  This book presents a technical and conceptual analysis of residential bioeconomy systems, focusing on the transformation of organic and inorganic waste streams into valuable resources within domestic and urban environments. It reframes waste not as a residual …
  datacite Hernandez García, Oscar Adrián 2026 置信度 0.66 PRMSMetabolic ArchitectureSustainable ArchitetureEnergy SystemsRenewable Energy
• Prim-Lex Theory: Eight-Dimensional Coherent Governance Framework and Five Operational Models ——A Unified Field Theory from Planetary Boundaries to Life's Prim-Fire
  Prim-Lex Theory (Economic Climatology) is a meta-level systems science that establishes the physical laws of the climate system as the ultimate boundary for all economic activities, under the core principle of “Climate as the Law, Economy as the Function.” Thi…
  datacite Xiaowang, Shen 2026 置信度 0.66 Prim-Lex Theory; Eight-Dimensional Coherent Governance; complexified unified field; NADH/NAD⁺ redox balance; planetary boundaries; Prim-Fire
• Prim-Lex Theory: Eight-Dimensional Coherent Governance Framework and Five Operational Models ——A Unified Field Theory from Planetary Boundaries to Life's Prim-Fire
  Prim-Lex Theory (Economic Climatology) is a meta-level systems science that establishes the physical laws of the climate system as the ultimate boundary for all economic activities, under the core principle of “Climate as the Law, Economy as the Function.” Thi…
  datacite Xiaowang, Shen 2026 置信度 0.66 Prim-Lex Theory; Eight-Dimensional Coherent Governance; complexified unified field; NADH/NAD⁺ redox balance; planetary boundaries; Prim-Fire
• TRIAD: Trans‑disciplinary Inference, Active Dynamics and Ontology (Version 6.1 — Public Monograph)
  TRIAD 6.1 Monograph: A Formal Ontology of Coherence, Trauma Therapy, and Safe AI — with Open Empirical Foundations and a Closed Engineering Core Author: Valeriia Zaiats (Валерия Заяц) ORCID: 0009-0002-6891-9227 Licence: CC BY‑NC‑ND 4.0 Cryptographic Attestatio…
  datacite Zaiats, Valeriia 2026 置信度 0.66 Active InferenceFree Energy PrincipleComputational PsychiatryAI SafetyAI Alignment
• MOLECULAR MIMICRY AND METABOLIC SABOTAGE: THE ARCHITECTURE O ANTIVITAMINS IN NEXT-GENERATION ONCOLOGY AND ANTIMICROBIAL THERAPEUTICS
  Modern pharmacology faces a critical bottleneck due to the metabolic plasticity of malignant tumors and the compounding crisis of antimicrobial resistance. Antivitamins—structural analogues of natural vitamins that decisively execute competitive inhibition—rep…
  datacite Tursunmaxamadova Muslima Gʻulom qizi , Abdiyeva Feruza Iskandarovna, Worldly Knowledge Publishing Centre 2026 置信度 0.66 Antivitamins, molecular mimicry, metabolic sabotage, competitive inhibition, antimicrobial resistance (AMR), targeted chemotherapy, bio-isosteres, enzyme cofactors, metabolic reprogramming, prodrug engineering, computational molecular dynamics.
• MOLECULAR MIMICRY AND METABOLIC SABOTAGE: THE ARCHITECTURE O ANTIVITAMINS IN NEXT-GENERATION ONCOLOGY AND ANTIMICROBIAL THERAPEUTICS
  Modern pharmacology faces a critical bottleneck due to the metabolic plasticity of malignant tumors and the compounding crisis of antimicrobial resistance. Antivitamins—structural analogues of natural vitamins that decisively execute competitive inhibition—rep…
  datacite Tursunmaxamadova Muslima Gʻulom qizi , Abdiyeva Feruza Iskandarovna, Worldly Knowledge Publishing Centre 2026 置信度 0.66 Antivitamins, molecular mimicry, metabolic sabotage, competitive inhibition, antimicrobial resistance (AMR), targeted chemotherapy, bio-isosteres, enzyme cofactors, metabolic reprogramming, prodrug engineering, computational molecular dynamics.
• Key Drivers of Soil Microbial Community Composition: From Foundational Principles to Biomedical Applications
  This extensive review provides a detailed synthesis of the factors driving soil microbial community composition, proposing a four-tier hierarchical model based on fundamental physiological needs: energy supply, environmental effectors, biological associations,…
  datacite microecology science 2026 置信度 0.66 soil microbiomemicrobial community compositionenvironmental stressorsamplicon sequencingecosystem multifunctionality
• Key Drivers of Soil Microbial Community Composition: From Foundational Principles to Biomedical Applications
  This extensive review provides a detailed synthesis of the factors driving soil microbial community composition, proposing a four-tier hierarchical model based on fundamental physiological needs: energy supply, environmental effectors, biological associations,…
  datacite microecology science 2026 置信度 0.66 soil microbiomemicrobial community compositionenvironmental stressorsamplicon sequencingecosystem multifunctionality
• MODELAGEM COMPUTACIONAL DA RESOLUÇÃO INFLAMATÓRIA MEDIADA POR TREGS EM CULTURAS 3D DE TECIDOS REGENERATIVOS: UMA ABORDAGEM COM PINNS E IMUNOMETABOLISMO
  Esta pesquisa apresenta uma estrutura computacional avançada destinada à investigação dos mecanismos de resolução inflamatória em tecidos regenerativos tridimensionais, integrando conceitos de imunologia, imunometabolismo, biofísica, biologia de sistemas e int…
  datacite VILELA SILVA, GUSTAVO 2026 置信度 0.66 TregsInflammatory ResolutionImmunometabolismPhysics-Informed Neural NetworksSystems Biology
• MODELAGEM COMPUTACIONAL DA RESOLUÇÃO INFLAMATÓRIA MEDIADA POR TREGS EM CULTURAS 3D DE TECIDOS REGENERATIVOS: UMA ABORDAGEM COM PINNS E IMUNOMETABOLISMO
  Esta pesquisa apresenta uma estrutura computacional avançada destinada à investigação dos mecanismos de resolução inflamatória em tecidos regenerativos tridimensionais, integrando conceitos de imunologia, imunometabolismo, biofísica, biologia de sistemas e int…
  datacite VILELA SILVA, GUSTAVO 2026 置信度 0.66 TregsInflammatory ResolutionImmunometabolismPhysics-Informed Neural NetworksSystems Biology
• The Secondary Signature of Immune System - [ Molecular Blueprint] -The Architecture of Secondary Stage - Sam Coole 2026 ©️
  Molecular Blueprint The Secondary Signature of the Immune System Framework / The Architecture of Secondary Stage Anti-Cooling-Coding-Maintenance (ACCM) Author: Sam Coole‌ Foreword This work is not a minor revision to existing immunology—it is a paradigm reset.…
  datacite COOLE, SAM 2026 置信度 0.66
• The Secondary Signature of Immune System - [ Molecular Blueprint] -The Architecture of Secondary Stage - Sam Coole 2026 ©️
  Molecular Blueprint The Secondary Signature of the Immune System Framework / The Architecture of Secondary Stage Anti-Cooling-Coding-Maintenance (ACCM) Author: Sam Coole‌ Foreword This work is not a minor revision to existing immunology—it is a paradigm reset.…
  datacite COOLE, SAM 2026 置信度 0.66
• HIV-1 - HOST-CENTRIC SEQUESTRATION PARADIGM SCIENTIFIC VALIDATION & HIV CURE PATH. AN ADVANCED LOGICAL SYNTHESIS & EMPIRICAL VALIDATION OF HIV-1 LATENCY AS ACTIVE CELLULAR SELF-PRESERVATION - QUIESCENCE CD4+ T CELLS
  Host-Centric Sequestration: An Advanced Logical Synthesis, Empirical Validation, and Systems-Level Architecture of HIV-1 Latency and Pathogen Containment as Active Cellular Self-Preservation **Sam Coole** *INDEPENDENT RESEARCHER* *DOI: 10.5281/zenodo.21394164 …
  datacite Coole, Sam 2026 置信度 0.66
• HIV-1 - HOST-CENTRIC SEQUESTRATION PARADIGM SCIENTIFIC VALIDATION & HIV CURE PATH. AN ADVANCED LOGICAL SYNTHESIS & EMPIRICAL VALIDATION OF HIV-1 LATENCY AS ACTIVE CELLULAR SELF-PRESERVATION - QUIESCENCE CD4+ T CELLS
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  datacite Coole, Sam 2026 置信度 0.66
• muratakdogan06/Surrogate-guided-MOBO-for-PHB-production: v1.0.0 (Metabolic Engineering submission)
  No description provided.
  datacite muratakdogan06 2026 置信度 0.66
• muratakdogan06/Surrogate-guided-MOBO-for-PHB-production: v1.0.0 (Metabolic Engineering submission)
  No description provided.
  datacite muratakdogan06 2026 置信度 0.66