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To systematically evaluate the diagnostic performance of machine learning (ML) models for predicting Ki-67 expression in renal tumors and assess their potential for clinical translation.
pubmed
Liu Y, Zhu G, Xiu Z
2026 Sep
置信度 0.82
-
The clinical course of psoriasis is characterised by marked heterogeneity. Despite the availability of standardised assessment instruments, long-term outcomes at the individual level-encompassing the durability of treatment response, the risk of relapse and th…
pubmed
Mao J, Yang Z, Cai Y, Shen Y 等
2026 Jul 13
置信度 0.82
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Hypertension (HT)-related erectile dysfunction (ED), a condition secondary to HT, is characterized by a persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. This study aimed to systematically analyze and visua…
pubmed
Wang J, Deng S, Teng F, Wang L 等
2026 Jun 26
置信度 0.82
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Aconitum carmichaelii Debeaux (Ranunculaceae), commonly used as Aconiti Lateralis Radix Praeparata (Fuzi), is a clinically important but highly toxic herb in traditional Chinese medicine. Despite long-standing use for cardiovascular, rheumatologic, gastrointes…
pubmed
Tan RY, Ooi PJ, Xu X, Wei X 等
2026
置信度 0.82
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Acute heart failure is defined as the rapid or gradual onset of signs and/or symptoms of heart failure severe enough to warrant unplanned hospital or emergency department care. As of 2019, an estimated 56.2 million individuals across 204 countries and territor…
pubmed
Cai J, Wang D, Yang L, Yuan Y
2026
置信度 0.82
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Pelvic inflammatory disease (PID) is a common infectious condition of the female upper genital tract that imposes a substantial global burden on women's reproductive health and overall quality of life. This narrative review aims to comprehensively synthesize c…
pubmed
Wang G, Zhang S
2026
置信度 0.82
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Classification of axial psoriatic arthritis (ax-PsA) within existing spondyloarthritis (SpA) criteria remains unclear. To clarify this issue, we compared the clinical features of ax-PsA and axial SpA (ax-SpA).
pubmed
Qiu Z, Chen Z, Yang Z, Xia R 等
2026
置信度 0.82
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Sensorineural hearing loss (SNHL) accompanied by vertigo is a condition with clinical heterogeneity. Understanding vascular underpinnings is crucial for management.
pubmed
Geng D, Yuan W, Wang Z, Zhang H 等
2026 Jan-Dec
置信度 0.82
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Metabolic dysfunction-associated fatty liver disease (MAFLD), as the most prevalent chronic liver disease globally, is closely related to the prevalence of metabolic syndrome. Liver fibrosis is a core stage in the progression of this disease, significantly inc…
pubmed
Hu C, Qiu Y, Zhong Y, Zhou W 等
2026 Jul 11
置信度 0.82
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Aluminum oxide nanoparticles (Al₂O₃-NPs) are currently widely applied, although they are known to induce electrocardiographic abnormalities, their crystal phase-dependent effects (including α- and γ-phases) and underlying electrophysi…
pubmed
Deng H, Xia M, Li Y, Yang J 等
2026 Jul 11
置信度 0.82
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By comparing conventional ultrasonography (US) and contrast-enhanced ultrasonography (CEUS) features of liver metastases of melanoma (LMM) with those of other common liver metastases from non-melanoma malignancies (non-LMM), a differential diagnosis nomogram w…
pubmed
Xu Y, Wu H, Tian H, Tang H 等
2026 Jul 11
置信度 0.82
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Surgical stress reprograms monocyte/macrophage populations, rendering patients more susceptible to infections and impairing postoperative recovery. However, the underlying mechanisms remain incompletely understood.
pubmed
Hua Q, Yao Y, Shi X, Wu S 等
2026 Oct 1
置信度 0.82
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Although non-invasive brain stimulation (NIBS) has been used to manage chronic musculoskeletal pain (CMP) and related emotional symptoms, the comparative efficacy of different NIBS techniques remains unclear. Therefore, this network meta-analysis (NMA) compare…
pubmed
Li Y, Ye X, Li S, Xu J 等
2026 Jul 11
置信度 0.82
-
Anxiety disorders, including phobias, are a growing public health concern, profoundly affecting quality of life. While existing research utilizes text-based and physiological data for detection, a multimodal, ecologically valid understanding of how anxiety is …
pubmed
Chen J, Gong J, Wang Z, Yang L 等
2026 Jul
置信度 0.82
-
Human catechol- O -methyltransferase (COMT) is a key target for neuropsychiatric disorders. Inhibiting COMT to prevent levodopa (L-DOPA) metabolism is a crucial strategy for Parkinson's disease (PD) treatment. While clinically used COMT inhibitors are primaril…
pubmed
Zhu R, Wang P, Qi SL, Zhang Y 等
2026 Jun
置信度 0.82
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Diabetic wound healing (DWH) is a multifaceted process hindered by impaired angiogenesis that usually leads to increased risks of infection and amputation. Targeting impeded angiogenic signals to restore the microenvironment favoring vascular network re-establ…
pubmed
Chen J, Qin S, Xing Z, Peng C 等
2026 Jun
置信度 0.82
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Inflammation and immuno-nutritional status are key determinants of tumor progression and therapeutic resistance in metastatic colorectal cancer (mCRC). This study aimed to assess the prognostic performance of composite biomarker global inflammatory-nutritional…
pubmed
Du M, Gao S, Shi Q, Han S 等
2026 Jun 30
置信度 0.82
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Childhood amblyopia is a common neurodevelopmental disorder that impairs visual function and binocular integration. Traditional treatments, such as occlusion and pharmacological penalization, are often limited by poor adherence, incomplete restoration of binoc…
pubmed
Dai Y, Yan X, Jiang M, Yang C
2026 Jun 30
置信度 0.82
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The ingestion of multiple magnetic foreign bodies (MMFBs) poses a growing risk of severe gastrointestinal injury in children, yet optimal management strategies remain debated due to the lack of largescale studies and international consensus. The study aims to …
pubmed
Yang B, Chen Y, Zhu Y, Chen W 等
2026 Jun 30
置信度 0.82
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Cervical radiculopathy typically presents with pain, numbness, and weakness in the affected nerve root distribution. When caused by bony foraminal stenosis, conventional posterior keyhole foraminotomy often necessitates extensive facetectomy, risking spinal in…
pubmed
Teng H, Yang M, Xiao D, Luo K 等
2026 Jul
置信度 0.82
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Up to now, attention deficit hyperactivity disorder (ADHD), a prevalent neurodevelopmental disorder in children, remains controversial efficiency of auricular therapy as an adjunctive treatment. Our study aims to synthesize the current evidence from RCTs and N…
pubmed
Wang S, Jin Y, Hong L, You Q 等
2026
置信度 0.82
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Accurately distinguishing between benign and malignant lesions in the larynx and hypopharynx is crucial for formulating individualized and precise treatment plans. Due to the low soft-tissue resolution of conventional computed tomography (CT), the diagnostic a…
pubmed
Mao Y, Wang P, Liu S, Yu M 等
2026 Jul 1
置信度 0.82
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The rupture and demyelination of nerve fibers after spinal cord injury (SCI) are primary contributors to neurological dysfunction. The axon attraction signal pathway mediated by netrin-1 is crucial for promoting the effective regeneration and repair of nerve a…
pubmed
Hao X, Ning Y, Dong Y, Rattanasakon P 等
2026 Jul 1
置信度 0.82
-
Ultrasound-guided needle-knife release of the transverse carpal ligament (TCL) has the potential to treat mild-to-moderate carpal tunnel syndrome (CTS). This study aimed to compare the clinical efficacy and safety of ultrasound-guided needle-knife release of t…
pubmed
Li YN, Li SL, Zhou QY
2026 Jul 1
置信度 0.82
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The aim of this study was to evaluate the association between socioeconomic status (SES) and all-cause mortality among individuals with diabetes. We also examined how individual SES components, including income, employment, education, and housing conditions, w…
pubmed
Konkol J, Pang C, Pu C
2026
置信度 0.82
-
Study DesignRetrospective Study.ObjectiveTo identify clinical risk factors for symptomatic epidural hematoma (SEH) following posterior lumbar decompression and fusion, with a particular focus on paraspinal muscle parameters.MethodsWe retrospectively analyzed d…
pubmed
Kong L, Guan H, Liang S, Chen R 等
2026 Jul 11
置信度 0.82
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Sessile serrated lesions (SSLs) represent a clinically significant challenge in colorectal cancer screening due to their flat morphology and association with interval cancers. Advanced endoscopic techniques such as wide-angle colonoscopy (WAC) and narrow-band …
pubmed
Liu B, Wang H, Li L, Huang X 等
2026 Jul 10
置信度 0.82
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With the deepening of societal aging, the older adults with comorbidities continues to grow, leading to a rise in the phenomenon of polypharmacy. As a key strategy to address polypharmacy, deprescribing has garnered increasing attention. This study aims to sys…
pubmed
Wang Y, Liu Z, Yu C, Li F 等
2026 Jul 10
置信度 0.82
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The pathophysiology of distal symmetric polyneuropathy (DSPN) is multifactorial, involving chronic hyperglycemia, oxidative stress, accumulation of advanced glycation end products, impaired microvascular perfusion, metabolic toxicity, and nutritional deficienc…
pubmed
Yang L, Deng R, Chen L
2026 Jul 10
置信度 0.82
-
In traditional Chinese medicine, herbal processing is used to modify the effects of herbs. Achyranthes bidentata BL (Niu Xi) is commonly used to treat atherosclerosis and cardiovascular diseases, in both raw (RC) and salted (SRC) forms. Salting is known to enh…
pubmed
Zou X, Su J, Gao B, Lei S 等
2026 Jul 10
置信度 0.82
-
Folate receptor alpha (FRα) is overexpressed in various epithelial ovarian carcinomas and has emerged as a potential therapeutic target. However, its expression pattern and clinical significance in borderline ovarian tumors (BOTs) and related low-grade s…
pubmed
Xu X, Yuan L, Meng H, Zhang L 等
2026 Jul 10
置信度 0.82
-
Polycystic ovary syndrome (PCOS) is associated with a significantly high risk of spontaneous abortion, yet there is a scarcity of clinical prediction models for early pregnancy loss in this patient population.
pubmed
Han Q, Li M, Li G, Xin M 等
2026 Jul 10
置信度 0.82
-
To investigate the differential expression of the c-Myc proto-oncogene in intestinal-type gastric cancer (ITGC), diffuse-type gastric cancer (DTGC), and gastric mucosal intestinal metaplasia (IM), and to assess its clinical significance.
pubmed
Lian L, Wang X, Shen J, Hu P 等
2026 Jul 10
置信度 0.82
-
Botulinum toxin (BTX) injection remains the mainstay for addressing dynamic glabellar lines. However, traditional morphology-based classifications may not exhaustively encompass the heterogeneous sums of glabellar muscular vectors. This study aims to propose a…
pubmed
Huang Z, Zhang X, Jiang C, Liu X 等
2026 Jul 10
置信度 0.82
-
Primary glaucoma is the leading cause of irreversible vision loss worldwide. Beyond visual impairment, it is frequently associated with anxiety, depression, reduced sleep quality, and diminished quality of life (QoL). Baduanjin, a traditional Chinese mind-body…
pubmed
Zeng Z, Li X, Ma X, Guo J 等
2026 Aug
置信度 0.82
-
To examine the dimension-level network linking patient safety climate and barriers to medication administration error reporting among nursing students in psychiatric clinical training.
pubmed
Lu W, Bai C, Kong L, Wei M 等
2026 Aug
置信度 0.82
-
Multidrug-resistant (MDR) bacterial pneumonia is a growing public health concern with limited treatment options and high mortality rates. Tanreqing injection, a traditional Chinese medicine with anti-inflammatory, antibacterial, and immunomodulatory properties…
pubmed
Shu B, Qiu T, Li K, Wang X 等
2026
置信度 0.82
-
Ovarian cancer (OC) is a highly fatal gynecologic malignancy with complex management challenges and limited long-term survival for advanced stages. Large language models (LLMs)-including systems such as GPT-4, Claude, Google Gemini, and others-are emerging art…
pubmed
Wang Y, Yao J, Tian J, Wang Y 等
2026 Jul 10
置信度 0.82
-
To test whether brief bedside photoplethysmography-derived heart-rate variability (PPG-HRV) provides objective information about pain, sleep, and affect in adults with chronic pain, and whether sleep moderates the pain-emotion association. We conducted a cross…
pubmed
Hu J, Xiao Y, Ma G, Yao B 等
2026 Jul 10
置信度 0.82
-
Hypercapnia is linked to a poor prognosis in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and severe community-acquired pneumonia (SCAP), and reduced early anti-inflammatory capacity in SCAP. However, its impact on AECOPD+SCAP patients …
pubmed
Mou S, Cai Q, Xu W, Wang X 等
2026 Jan-Dec
置信度 0.82
-
BackgroundHospital-associated venous thromboembolism (HA-VTE) is the leading preventable cause of death among patients undergoing gynecological surgery. Standard risk assessment methodologies, such as the Caprini score, which is a commonly utilized tool for ri…
pubmed
Yao Y, Lin H, Wang C, Ma D 等
2026 Jan-Dec
置信度 0.82
-
We examined and compared microbiological variables, trace elements, and biological markers in autistic children.
pubmed
Qu K, Gao Z, Chang C, Gao M
2025 Nov
置信度 0.82
-
To optimize clinical management of ulcerative colitis (UC) and evaluate the efficacy of traditional Chinese medicine (TCM), conventional medicine (CM), and integrated TCM- CM therapies.
pubmed
Li X, Sha Z
2026
置信度 0.82
-
New-onset atrial fibrillation (NOAF) is a common in-hospital complication among patients with acute ST-segment elevation myocardial infarction (STEMI) and is closely associated with adverse outcomes. The remnant cholesterol inflammatory index (RCII), a novel c…
pubmed
Xu Y, Hu X, Qian Y, Ding H 等
2026
置信度 0.82
-
The implementation of artificial intelligence (AI) in healthcare increasingly depends not only on algorithmic performance but also on how patients and healthcare professionals experience, trust, accept, and engage with AI-enabled systems. Although many bibliom…
pubmed
Li X, Jing C, Gong Z, Zhang J 等
2026
置信度 0.82
-
To evaluate the predictive value of the Vasoactive Inotropic Score (VIS) for 28-day mortality in intensive care unit (ICU) patients with atrial fibrillation (AF)-related hemodynamic deterioration, to determine its optimal cutoff value, and to analyze its indep…
pubmed
Guo Z, Chang X, Qin X, Fang J 等
2026 Jun
置信度 0.82
-
Stroke-related hemiplegia often results in significant lower limb dysfunction, severely affecting walking ability, balance, and daily activities. Although various non-pharmacological interventions have shown potential benefits, the optimal rehabilitation strat…
pubmed
Zhang D, Yang Y, Xu G, Wang L 等
2026 Jul 9
置信度 0.82
-
To investigate the regional distribution characteristics of different Demodex species in eyelash follicles of patients with squamous blepharitis, and to explore the correlation between Demodex distribution and ocular surface parameters.
pubmed
Wen H, Li X, Wang H, Wang J 等
2026 Jul 9
置信度 0.82
-
This study aims to investigate the effects of a peer education-based model utilizing 5G remote rehabilitation guidance with wearable smart devices on patients with coronary heart disease undergoing percutaneous coronary intervention (PCI), along with the influ…
pubmed
Long Y, Xu T, Yang Y, Fu X 等
2026 Jul 9
置信度 0.82
-
Diarrheagenic Escherichia coli (DEC) is a leading cause of infectious diarrhea globally, yet its epidemiology in high-altitude human populations remains largely unexplored. This study aimed to determine the prevalence, pathotype distribution, antimicrobial res…
pubmed
Pan H, Han X, Zhou H, Zhang L
2026 Sep
置信度 0.82
-
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Abstract Aldous Huxley underwent a gradual intellectual shift from Western scientific rationalism toward Eastern medical and philosophical traditions as a lifelong patient and a pacifist. This transition marked a movement from curing disease toward cultivating…
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Chengyi ZHOU
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Accurate characterization of the chemical composition of complex traditional Chinese medicine (TCM) is an essential foundation for the modern scientific interpretation of TCM principles. Mass spectrometry is the most dominant technique in current research on t…
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Abstract Traditional Chinese medicine (TCM) is characterized by complex, multicomponent herbal formulations that challenge the conventional “one drug, one target” paradigm. Network pharmacology, through the construction of multilayered drug-target-disease netw…
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