-
Inflammation is a vital response involved in host defense and tissue repair; however, chronic inflammation is closely associated with the progression of numerous diseases, including arthritis, diabetes, cardiovascular disorders, neurodegenerative diseases, can…
datacite
Dehar, Parminder Singh, Basole, Smitaa, Padmaja, Vasa, Adil, Mohd 等
2026
置信度 0.66
-
The modern medical reductionist system relies on linear superposition dynamics models to analyze life mechanisms, which struggles to fully explain core TCM principles such as holistic regulation, formula synergy, and syndrome progression. This has also led to …
datacite
Xu, Jianjun
2026
置信度 0.66
-
The modern medical reductionist system relies on linear superposition dynamics models to analyze life mechanisms, which struggles to fully explain core TCM principles such as holistic regulation, formula synergy, and syndrome progression. This has also led to …
datacite
Xu, Jianjun
2026
置信度 0.66
-
Rights-filtered curated registries, formal calibration checkpoints and diagnostics, complete descriptive pathway outputs, audit records, figures, editable tables, checksums and executable environment specifications supporting an entity-, lineage-, dependence- …
datacite
Fan, Gaojun, Ma, Yan, Wang, Xiaoyun
2026
置信度 0.66
transcriptomicsdata provenanceshared controlssampling covariancesimulation-based calibration
-
Rights-filtered curated registries, formal calibration checkpoints and diagnostics, complete descriptive pathway outputs, audit records, figures, editable tables, checksums and executable environment specifications supporting an entity-, lineage-, dependence- …
datacite
Fan, Gaojun, Ma, Yan, Wang, Xiaoyun
2026
置信度 0.66
transcriptomicsdata provenanceshared controlssampling covariancesimulation-based calibration
-
This article presents a comprehensive introduction to holistic health — the integrated approach to human wellbeing that treats the person as a unified system of body, mind, and spirit rather than a collection of separate symptoms requiring isolated interventio…
datacite
Rout, Narayan
2026
置信度 0.66
holistic health guidenaturopathy natural healingintegrative medicineAyurveda holistic healthmind body medicine
-
This article presents a comprehensive introduction to holistic health — the integrated approach to human wellbeing that treats the person as a unified system of body, mind, and spirit rather than a collection of separate symptoms requiring isolated interventio…
datacite
Rout, Narayan
2026
置信度 0.66
holistic health guidenaturopathy natural healingintegrative medicineAyurveda holistic healthmind body medicine
-
Traditional medicine exists as an essential part of worldwide healthcare systems which developed through indigenous medical systems and traditional cultural practices and natural healing methods. Ayurveda and Traditional Chinese Medicine established essential …
datacite
Dr. Priyanka, Kumari
2026
置信度 0.66
Traditional MedicineComplementary and Alternative Medicine (CAM)Global Health, Integrative HealthcareHerbal Medicine
-
Traditional medicine exists as an essential part of worldwide healthcare systems which developed through indigenous medical systems and traditional cultural practices and natural healing methods. Ayurveda and Traditional Chinese Medicine established essential …
datacite
Dr. Priyanka, Kumari
2026
置信度 0.66
Traditional MedicineComplementary and Alternative Medicine (CAM)Global Health, Integrative HealthcareHerbal Medicine
-
Infection with the chronic hepatitis B virus (HBV) is a global public health problem. It is estimated that it infects over 250 million people, and it causes complications such as cirrhotic liver, hepatic fibrosis, liver failure, and hepatocellular carcinoma. T…
datacite
Chinni Krishna Khandavalli, Godana Kunaye Halake* Jagannadham Nutha Na Yaswanth, Dr. Eswar Kumar Kilari, Dr. Routhu Pratyusha
2026
置信度 0.66
Hepatitis B Virus, Polyherbal Therapy, Hepatoprotection, Phyllanthus, Antiviral Activity, Liver Diseases, Herbal Medicine
-
Infection with the chronic hepatitis B virus (HBV) is a global public health problem. It is estimated that it infects over 250 million people, and it causes complications such as cirrhotic liver, hepatic fibrosis, liver failure, and hepatocellular carcinoma. T…
datacite
Chinni Krishna Khandavalli, Godana Kunaye Halake* Jagannadham Nutha Na Yaswanth, Dr. Eswar Kumar Kilari, Dr. Routhu Pratyusha
2026
置信度 0.66
Hepatitis B Virus, Polyherbal Therapy, Hepatoprotection, Phyllanthus, Antiviral Activity, Liver Diseases, Herbal Medicine
-
Danshen (Salvia miltiorrhiza) tanshinones and Honghua (Carthamus tinctorius) safflower yellow inhibit PHD enzymes, stabilizing HIF-1α which upregulates VEGF and EPO, enhancing melanocyte survival through improved oxygen delivery and direct HIF-1α-MITF crosstal…
datacite
MedicOath Autonomous Discovery Engine
2026
置信度 0.66
Oculocutaneous albinismdrug repurposingMedicOathnovel_target
-
Danshen (Salvia miltiorrhiza) tanshinones and Honghua (Carthamus tinctorius) safflower yellow inhibit PHD enzymes, stabilizing HIF-1α which upregulates VEGF and EPO, enhancing melanocyte survival through improved oxygen delivery and direct HIF-1α-MITF crosstal…
datacite
MedicOath Autonomous Discovery Engine
2026
置信度 0.66
Oculocutaneous albinismdrug repurposingMedicOathnovel_target
-
Traditional medicine exists as an essential part of worldwide healthcare systems which developed through indigenous medical systems and traditional cultural practices and natural healing methods. Ayurveda and Traditional Chinese Medicine established essential …
datacite
Dr. Priyanka, Kumari
2026
置信度 0.66
Traditional MedicineComplementary and Alternative Medicine (CAM)Global Health, Integrative HealthcareHerbal Medicine
-
Traditional medicine exists as an essential part of worldwide healthcare systems which developed through indigenous medical systems and traditional cultural practices and natural healing methods. Ayurveda and Traditional Chinese Medicine established essential …
datacite
Dr. Priyanka, Kumari
2026
置信度 0.66
Traditional MedicineComplementary and Alternative Medicine (CAM)Global Health, Integrative HealthcareHerbal Medicine
-
This is a wooden acupuncture model made in Japan in 1681. It was probably used to train students of acupuncture, a part of traditional Chinese medicine (TCM). In acupuncture, practitioners insert fine needles into the skin of a patient, at precise positions ca…
datacite
sciencemuseum
2019
置信度 0.66
-
This is a wooden acupuncture model made in Japan in 1681. It was probably used to train students of acupuncture, a part of traditional Chinese medicine (TCM). In acupuncture, practitioners insert fine needles into the skin of a patient, at precise positions ca…
datacite
sciencemuseum
2019
置信度 0.66
-
crossref
Yan-qiu ZHANG
2009-10-09T11:08:16Z
置信度 0.70
-
crossref
Rui Han
2021-12-17T18:09:32Z
置信度 0.70
-
crossref
Xu-shan XIE
2009-01-11T04:57:17Z
置信度 0.70
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crossref
Xie Zhufan
2021-12-17T16:07:41Z
置信度 0.70
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crossref
Qiong HUANG
2009-06-11T09:03:14Z
置信度 0.70
-
Objectives. This study aimed to examine the efficacy and safety of acupoint catgut embedding (ACE) for obesity over a 16-week treatment period using sham stimulation as the control. Methods. A multicenter, randomised, parallel, sham-controlled trial was conduc…
crossref
Xia Chen, Wei Huang, Dan Wei, Ji-Ping Zhao 等
2022-02-27T20:50:08Z
置信度 0.70
-
crossref
万森 孙
2020-11-27T02:09:07Z
置信度 0.70
-
crossref
Zhang Junhong, Liu Xiaohong
2008-05-22T12:53:21Z
置信度 0.70
-
crossref
Ting-Ming Li
2021-12-17T18:08:51Z
置信度 0.70
-
crossref
Stevenson Xutian, John Junion, Louis Wozniak
2014-10-13T03:56:00Z
置信度 0.70
-
crossref
Zhufan Xie
2021-12-17T15:40:29Z
置信度 0.70
-
crossref
磊 李
2015-11-16T01:54:23Z
置信度 0.70
-
The eyes are the bridge between Zang-Fu organs and the outside world. They connect with all meridians/channels of the body either directly or indirectly to form the eye unit. The close association of eye function with the Zang-Fu organs allows diagnosis of org…
crossref
Han-Wen Cheng, Allison Faber Marshall
2025-09-16T08:22:57Z
置信度 0.70
-
Swine H1N1 influenza is a critical zoonotic pathogen threatening pig industry economy and public health. The host molecular regulatory network and core genes of H1N1 infection remain unclear, hindering targeted prevention and therapy. Traditional experimental …
pubmed
Guo Y, Liu J, He Z, Han X 等
2026
置信度 0.82
-
Onychocryptosis-associated paronychia is a common condition with frequent recurrence after conventional treatment. Minimally invasive, nail-preserving strategies remain insufficiently standardized and have not been extensively evaluated within structured clini…
pubmed
Li T, Liang J, Li J, Yang F 等
2026
置信度 0.82
-
To systematically evaluate the anti-osteoporotic efficacy of curcumin in preclinical models and utilize an exploratory small-sample machine learning (ML) framework to examine potential contributors to heterogeneity and generate preliminary dose-duration hypoth…
pubmed
Ma Y, Bai J, Wang R, Wang Y 等
2026
置信度 0.82
-
Seasonal allergic rhinitis (SAR) is a pollen-triggered condition causing nasal inflammation and quality of life impairment. Pumecitinib, a topical Janus kinase (JAK) inhibitor may modulate allergic inflammation. We evaluated the efficacy, safety, and pharmacok…
pubmed
Li J, Wang M, Zhang X, Wang X 等
2026 Sep
置信度 0.82
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To evaluate whether selective intra-arterial hypothermia during mechanical thrombectomy is associated with greater preservation of initially hypoperfused tissue in patients with anterior-circulation large-vessel occlusion.
pubmed
Bi Q, Wang Y, Fu W, Wang Q 等
2026
置信度 0.82
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Aging is a major risk factor for atherosclerosis (AS), but the aging-associated molecular characteristics and immune heterogeneity of AS remain incompletely understood. This study aimed to identify aging-related hub genes and characterize immune landscapes acr…
pubmed
Fan Q, Chen K, Liu J, Diao X 等
2026 Aug
置信度 0.82
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Conventional treatments for dry eye disease, such as artificial tears and anti-inflammatory drugs, can only alleviate symptoms, and it is difficult to achieve etiological repair with these treatments. In recent years, stem cell and exosome-based therapies have…
pubmed
Zhang H, Wang L, Lin C, Li N 等
2026 Aug 25
置信度 0.82
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Sepsis-associated encephalopathy (SAE) is a clinical condition that is characterized by cognitive dysfunction induced by a systemic infection. This study was designed to assess the effect of the Taohe Chengqi decoction (THCQ) on SAE.
pubmed
Yan X, Liu J, Chen S, Zhu Y 等
2026 Aug
置信度 0.82
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Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph-node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibit…
pubmed
Wang SS, Wei HC, Jiang L, Shao YS
2026 Aug 26
置信度 0.82
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Chronic low back pain (CLBP) is characterized by persistent neuroinflammation and metabolic dysregulation, extending beyond local tissue injury to central neural maladaptation. While manual therapy (MT) is a clinically validated intervention, its capacity to m…
pubmed
Xie L, Yin Z, Shao L, Ma J 等
2026
置信度 0.82
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Prediabetes affects 35% of Chinese adults and is associated with increased risks of cardiovascular disease and mortality. However, findings are inconsistent on the effects of lifestyle and pharmacological interventions in the prediabetes population achieving r…
pubmed
He S, Hao Y, Tu P, Wang S 等
2026 Aug 26
置信度 0.82
-
pubmed
Xie M, Ding X, Zhai X, Li M 等
2026
置信度 0.82
-
BACKGROUND Ischemic stroke causes severe neurological damage, and promoting angiogenesis in the ischemic penumbra is critical for neurovascular reconstruction and functional recovery. Astragaloside IV (AS-IV) and Tetramethylpyrazine (TMP) are a classic Chinese…
pubmed
Li G, Lu Y, Huang L, Zhu J 等
2026 Aug 27
置信度 0.82
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Agricultural by-products and Chinese medicine crop residues, as non-traditional animal feed, have great potential to alleviate the scarcity of traditional feed and reduce the environmental burden. In this study, the effects of adding fermented ginseng by-produ…
pubmed
Chen H, Liu Y, Zhang S, Jin Y 等
2026 Aug 21
置信度 0.82
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This study aimed to explore the protective effects of different concentration combinations of four traditional Chinese medicine (TCM) monomers (Eleutheroside E, Anemoside B4, Forsythoside A, and Esculin) on porcine intestinal epithelial cell (IPEC-J2) damage i…
pubmed
Wang Y, Shen Z, Lv L, Li Z 等
2026 Jul 30
置信度 0.82
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African swine fever (ASF), caused by African swine fever virus (ASFV), is a highly contagious disease that has brought severe economic losses to the global swine industry. ASFV dUTPase is a key enzyme modulating viral nucleotide metabolism and genome stability…
pubmed
Zhao M, Dai X, Tang H, Wu C 等
2026 Jul 23
置信度 0.82
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Adult deep neck infection (DNI) is a potentially life-threatening condition associated with significant morbidity and mortality. Contemporary large-scale data characterizing long-term microbial evolution and clinical outcome trends in adult DNI remain limited.…
pubmed
Liu FC, Lu A, Yang PR, Tsai YT 等
2026 Aug 18
置信度 0.82
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Medicinal plants are important sources of secondary metabolites (SMs), but their production is constrained by resource shortages, low cultivation efficiency, and continuous cropping obstacles. As the "second genome" of host plants, the plant microbiome is deep…
pubmed
Wang E, Zhang Y, Yue R, Wang Y 等
2026
置信度 0.82
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H9N2 avian influenza virus (AIV) continues to mutate, leading to immunosuppression and secondary infections in poultry. Traditional inactivated vaccines mainly induce humoral immunity and have limited cross-protection efficacy against various subtypes of virus…
pubmed
Ji J, Lin Y, Zhu Z, Yue K 等
2026 Jul 24
置信度 0.82
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Enterovirus alphacoxsackie (EV-A) is a highly diverse viral species containing at least 25 serotypes with diverse biological and clinical characteristics. EV-A can cause diseases ranging from asymptomatic infections to severe neurological disorders, as well as…
pubmed
Zhu X, Guo Z, Wang Q, Ge XY 等
2026 Jul 24
置信度 0.82
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Sporophyte propagation in medicinal ferns is influenced by explant type, owing to their distinctive two-phase life cycle: haloid gametophyte and sporophyte. However, few studies have systematically investigated sporophyte proliferation using different explants…
pubmed
Han Y, Ren Y, Cao Y, Zhen S 等
2026 Aug 21
置信度 0.82
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Sphingolipids, a class of lipids, are widely present in the cell membranes of all eukaryotic and some prokaryotic organisms. These lipids play crucial roles in the formation of the lipid bilayer and are categorised into several groups, including sphingomyelins…
pubmed
Li M, Yao Y, Li T, Cai T 等
2026 Aug 20
置信度 0.82
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Immunosenescence is a major contributor to age-associated morbidity, yet microbiota-directed strategies capable of restoring immune homeostasis remain insufficiently validated. Medicinal plant polysaccharides (MPPs) are structurally diverse macromolecules that…
pubmed
Mu K, He M, Liao R, Shao C 等
2026
置信度 0.82
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Cordyceps polysaccharides (CSP) have shown neuroprotective potential in models of ischemic stroke, but the underlying mechanisms remain to be clarified.
pubmed
Chen Y, Wang H, Gai C, Li X 等
2026 Aug 7
置信度 0.82
-
Background/Objectives : Oral solid dosage forms of traditional Chinese and ethnic medicines are currently undergoing modernisation. The objective of this study is to explore the scope for formulation variation arising from batch-to-batch fluctuations in interm…
pubmed
Deng X, Mu D, Song F, Miao Y 等
2026 Aug 16
置信度 0.82
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Kaempferol is a natural flavonol compound widely present in various single-herb remedies and compound formulations used for the treatment of ocular diseases. Despite its inherent pharmaceutical limitations, accumulating evidence indicates that kaempferol exert…
pubmed
Ma Z, Zhang D, Chen X, Zhang F
2026 Aug 12
置信度 0.82
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Breast cancer treatment still faces challenges including local recurrence, systemic toxicity, tumor heterogeneity, drug resistance, and immunosuppression. Conventional systemic administration provides limited exposure at the tumor site and exhibits significant…
pubmed
Jiao Y, Zuo H, Chen J, Zheng S 等
2026 Aug 9
置信度 0.82
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Periodontitis, a chronic inflammatory disease driven by plaque biofilm, is a leading cause of tooth loss in adults worldwide. Effective treatment requires not only infection and inflammation control but, more critically, functional regeneration of the periodon…
pubmed
Zhang R, Zeng Y, Lin L, Jin L 等
2026 Jul 28
置信度 0.82
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During the X-ray Diffraction (XRD) identification of the traditional Chinese medicine Os Draconis , the identification model often suffers from limited classification accuracy due to the difficulty in determining optimal parameters. To address this issue, this…
pubmed
Wang Y, Zhai H, Deng J, Cheng L 等
2026 Aug 21
置信度 0.82
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This study investigates the antioxidant efficacy and selectivity of a quercetagetin-rich extract (QG, 89% purity) from Tagetes erecta in soybean oil under accelerated storage conditions (65 °C, 56 days). Using gas chromatography-mass spectrometry (GC-MS) …
pubmed
Huang X, Fang M, Wang Z, Zheng Q 等
2026 Aug 19
置信度 0.82
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Cancer remains one of the leading causes of global mortality, with its incidence continuing to rise due to population growth, aging, lifestyle factors, and environmental exposures. Despite significant advances in early diagnosis and therapeutic strategies, the…
pubmed
Musazade E, Qin L, Yu F, Li N 等
2026 Aug 17
置信度 0.82
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Efficient and sustainable isolation of cellulose from sugarcane tops (ST), a major sub-fraction of sugarcane trash, is of great significance for the high-value valorization of cellulose and its subsequent conversion into substrates for biomaterials. This study…
pubmed
Zhang J, Yin JL, Chen LY, Gao J 等
2026 Aug 16
置信度 0.82
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Abelmoschus manihot (L.) flowers are widely used in traditional Chinese medicine, whereas the roots are often discarded as agricultural waste. The compact cellular and tissue architecture of the roots hinders the release of intracellular metabolites, thus impe…
pubmed
Wang J, Liu X, Zhuang D, Ren Z 等
2026 Aug 13
置信度 0.82
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Lonicera japonica Thunb. (honeysuckle), a traditional herb with "food-medicine homology" status in Chinese medicine, is valued for its antipyretic and detoxifying properties. This review systematically summarizes its chemical composition-over 507 identified co…
pubmed
Gao J, Li L, Li Y
2026 Aug 11
置信度 0.82
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PARP1/2 inhibitors have received FDA approval for pancreatic cancer harboring BRCA1/2 mutations and homologous recombination (HR) deficiency; however, their limited indications restrict their broader clinical application. Previous studies have demonstrated tha…
pubmed
Yang Y, Huang L, Du Y, Zhu Q 等
2026 Aug 10
置信度 0.82
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The rapid emergence of antimicrobial resistance necessitates the development of novel antimicrobial agents with improved efficacy and selectivity. In this study, a dermatoxin-like peptide, dermatoxin-PD1, was identified from the skin secretion of Pachymedusa d…
pubmed
Cheng S, Zai Y, Peng J, Xiang J 等
2026 Aug 7
置信度 0.82
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In the original publication [...].
pubmed
Hu Z, Liu H, Wu W, Ali T 等
2026 Jul 27
置信度 0.82
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Hyperuricemia (HUA) is a key pathological basis for gout and uric acid (UA) nephropathy, and its increasing global prevalence presents a substantial public health challenge. Natural products (NPs) have emerged as a research hotspot due to their potential to re…
pubmed
Pan S, Li Y, Lin Z, Lin Z 等
2026 Aug 14
置信度 0.82
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Background/Objective: Cinnamaldehyde (CA) is a naturally occurring bioactive compound derived from the leaves, bark, roots, and flowers of the Chinese medicinal plant Cinnamomum cassia . It exhibits a broad spectrum of pharmacological properties, encompassing …
pubmed
Shen M, Shi Q, Gao S, Chen B 等
2026 Aug 13
置信度 0.82
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Background : Male infertility, largely driven by declining sperm quality, is a growing global concern. Radix Bupleuri Chinensis (Chaihu, CH)-a key component of traditional formulas such as Chaihu Shengjing Tang and Chaihu Shugan San-has been clinically used to…
pubmed
Wang M, Fu Y, Yuan P, Zeng Y 等
2026 Aug 13
置信度 0.82
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Background: Hyperuricemia is a well-established risk factor for both chronic kidney disease and gout. Currently available urate-lowering drugs, however, are frequently compromised by hepatorenal toxicity and gastrointestinal adverse effects. Cinnamaldehyde, th…
pubmed
Sun Y, Tan H, Zhang J, Zhang Z 等
2026 Aug 10
置信度 0.82
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Background : Dangguibuxue decoction (DD), containing Angelica sinensis (Oliv.) Diels (AS) and Astragalus membranaceus (Fisch.) Bge. (AM) (1:5), is a well-known traditional Chinese medicine (TCM) used for strengthening qi and nourishing the blood. DD has shown …
pubmed
Liu S, Meng J, Zhao Y, Li C 等
2026 Aug 1
置信度 0.82
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Objective: While Sanzi Sijun Formula (SSF) has exhibited preliminary efficacy against metabolic dysfunction-associated steatotic liver disease (MASLD), its mode of action remains undefined. This study therefore aimed to unravel its core therapeutic mechanisms.…
pubmed
Ding J, Liu T, Huang P, Yang L 等
2026 Jul 29
置信度 0.82
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Irinotecan is a first-line medication for metastatic colorectal cancer. It is known that irinotecan-induced delayed diarrhea is closely related to metabolic processes in the human body. In particular, the synergies of multiple metabolic enzymes/transporters me…
pubmed
Wang Y, Li M, Hu Q, Liu J 等
2026 Jul 29
置信度 0.82
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Background/Objectives: For over two millennia, Ganoderma lucidum has served as a traditional remedy, yet its translation into evidence-based therapy remains stymied by a persistent obstacle. Potent in vitro activities consistently fail to translate in vivo, a …
pubmed
Qu Y, Zhao X, Liu H, Ren R 等
2026 Jul 27
置信度 0.82
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Background/Objectives : Uterine dysfunction contributes to infertility in PCOS. Jiawei Qi Gong Wan (JQGW) is used to improve endometrial homeostasis, but its mechanism is unclear. This study investigated whether JQGW improves uterine function via gut microbiot…
pubmed
Zheng R, Song J, Li J, Shen Y 等
2026 Jul 24
置信度 0.82
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Major airway diseases, including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis and chronic rhinosinusitis without nasal polyps (CRSsNP), frequently coexist and share inflammatory, epithelial and remodeling features. However, whether thes…
pubmed
Tu T, Guo Y, Li Q, Liu Y 等
2026 Aug 20
置信度 0.82
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Vivipary adversely affects the production process of the cucumber seed industry and greatly limits the popularization of cucumber varieties. Identification of the cucumber seed vivipary phenotype and screening of vivipary-associated genes will provide importan…
pubmed
Xu J, Fan T, Mo Y, Cai J 等
2026 Aug 19
置信度 0.82
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Diarrhea-predominant irritable bowel syndrome (IBS-D) frequently occurs alongside depression, greatly impairing patients' life quality, with limited targeted treatments. Low-molecular-weight peptides (LMWPs) from Musca domestica larvae exert gut-protective bio…
pubmed
Zhang X, Jin X, Ma H, Chu F
2026 Aug 19
置信度 0.82
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Coronary heart disease (CHD) is a leading cause of morbidity and mortality, driven by metabolic remodeling, vascular inflammation, and perivascular adipose tissue (PVAT) dysfunction. We integrated bulk transcriptomic datasets to develop a machine learning-base…
pubmed
Yang H, Zhang Y, Yu Y, Bai Y 等
2026
置信度 0.82
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Neuroinflammation plays a central role in Alzheimer's disease (AD). Glycyrrhizin (GL), a major component of licorice, exhibits anti-inflammatory effects, but its effects on AD pathology remain unclear. To investigate the effects of GL (18β-glycyrrhizin, …
pubmed
Wang G, Hiramoto K, Ma N, Ohnishi S 等
2026 Aug 19
置信度 0.82
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Gaseous air pollution is a major environmental risk factor for atherosclerosis, yet the specific molecular networks linking Gaseous air pollution to atherosclerosis are not fully characterized. This study aimed to elucidate how gaseous pollutants drive atheros…
pubmed
Hai H, Wang Q, Li J, Wang J 等
2026 Aug 18
置信度 0.82
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Kansui Radix, the root of Euphorbia kansui , was first described in Shen Nong Ben Cao Jing as a traditional Chinese medicine, known for its effects of expelling water, reducing edema, and dissipating masses. It is traditionally indicated for conditions such as…
pubmed
Cheng Z, Chen X, Wang S, Bai Y 等
2026 Aug 16
置信度 0.82
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Lonicerae japonicae flos (LJ), derived from Lonicera japonica Thunb., is a classic medicinal and edible plant traditionally used to clear heat, detoxify, and disperse wind-heat. It is widely consumed as a health tea or food additive and played a significant ro…
pubmed
Yu C, Shu Y, Li X, Li Z 等
2026 Aug 14
置信度 0.82
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Bisphenols (BPs) are widespread environmental endocrine disruptors, but their potential depression-related neurotoxicity has not been systematically assessed. Here, we combined machine learning (ML), network toxicology, molecular docking, and in vivo experimen…
pubmed
Xie L, Yuan S, Gan L, Ma R 等
2026 Aug 13
置信度 0.82
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Lycium barbarum polysaccharides (LBPs), the primary bioactive components extracted from the traditional medicinal and edible plant Lycium barbarum L., have attracted extensive attention in biomedical research due to their superior anti-inflammatory, immunomodu…
pubmed
Bai J, Fu J, Huang Y, Liu Q 等
2026
置信度 0.82
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Protein-ligand interactions (PLIs) play a crucial role in drug discovery, and accurately predicting protein-ligand binding affinity (PLA) remains a central challenge in computer-aided drug design. Although graph neural networks (GNNs) have demonstrated conside…
pubmed
Li J, Li H, Wu D, He W 等
2026 Aug 12
置信度 0.82
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Yeast hydrolysate (YH) has attracted increasing interest as a functional feed additive because of its potential benefits for maternal nutrition and offspring development. However, its effects on milk composition and the physiological responses of donkey foals …
pubmed
Wen Z, Li Z, Wang T, Wang Y 等
2026 Aug 11
置信度 0.82
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Insomnia is associated with disrupted sleep architecture, hippocampal pathological alterations, neurotransmitter imbalance, and neuroinflammatory responses. This study evaluated the effects of the Prunella vulgaris compound (PVC) on sleep architecture and hipp…
pubmed
Wang K, Zhang H, Zhou C, Sun Z 等
2026 Jul 31
置信度 0.82
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Wolfiporia extensa (Peck) Ginns (WE) is a fungus widely used in Traditional Chinese Medicine. Its four medicinal parts, Poria (WP), Rubra Poria (RP), Poriae Cutis (PC), and Poria Cum Pini Radix (PPR), are prescribed for distinct therapeutic purposes; however, …
pubmed
Deng SX, Chen LG, Hsiung SY, Le VTT 等
2026 Jul 27
置信度 0.82
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As the global population ages rapidly, demand for safe and effective strategies to promote healthy aging grows markedly. Natural bioactive compounds, with favorable biosafety profiles and multi-target regulatory properties, have become a core focus in developi…
pubmed
Zhao M, Wang W, Lai H, Zhou L 等
2026
置信度 0.82
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Rab proteins are key members of the Ras superfamily that regulate vesicular trafficking in eukaryotic cells, ensuring accurate cargo transport and cellular homeostasis. To investigate the functional role of Rab proteins, RNA interference (RNAi) was employed to…
pubmed
Abbas M, Zhao Y, Basit A, Zhang J 等
2026 Aug 3
置信度 0.82
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Background/Objectives : Diabetes mellitus-induced erectile dysfunction (DMED) is characterized by severe endothelial and smooth-muscle dysfunction and reduced responsiveness to conventional therapy. Guanxinning tablet (GXN), a traditional Chinese medicine comp…
pubmed
Xin S, Liu X, Mao J, Yang B 等
2026 Aug 7
置信度 0.82
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Background/Objectives : Baicalin (BA), a natural flavonoid with anti-inflammatory activity, shows promise for treating acute pharyngitis (AP) but its clinical application is hindered by poor water solubility and low oral bioavailability. Based on the clinicall…
pubmed
Wang X, Qian Z, Gong Z, Sun L 等
2026 Jul 31
置信度 0.82
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Background : Global aging has led to a rise in neurodegenerative diseases. Neuroinflammation constitutes a core pathological mechanism in these disorders. The Kongsheng Zhenzhong Pill (KSZZP), a modern preparation derived from a classical Chinese herbal formul…
pubmed
Zhang H, Wei D, Han X, Wu W 等
2026 Jul 24
置信度 0.82
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With global restrictions on in-feed antibiotics, sustainable alternatives are urgently needed to combat weaning-induced intestinal dysfunction in piglets. Fucoidan, a bioactive seaweed polysaccharide, exerts beneficial effects on gut health due to its immunomo…
pubmed
Liu P, Li P, Lin Q, Li M 等
2026 Aug 11
置信度 0.82
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Diabetic kidney disease (DKD) differs transcriptionally across renal compartments. We assessed whether Lycii Fructus-annotated targets showed reproducible DKD-associated changes and enrichment beyond matched expectations. Linked glomerular (GSE30528) and tubul…
pubmed
Zou J, Tian X, Sun Y, Wang S
2026 Aug 14
置信度 0.82
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The structural and immunomodulatory properties of arabinogalactan proteins (AGPs) from edible medicinal plants remain largely unexplored. Here, A homogenous AG-II-like arabinogalactan protein (CTSP-W2, 9862 Da) was isolated from Cynanchum thesioides via hot-wa…
pubmed
Dan M, Zhao P, Ga L, Bai W 等
2026 Aug 8
置信度 0.82
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Colorectal cancer (CRC) remains a major clinical challenge owing to its high mortality and limited therapeutic options, highlighting the urgent need for novel anticancer agents. Andrographolide (AGL), the principal bioactive compound isolated from the medicina…
pubmed
Guan H, Li Y, Xu M, Sun W 等
2026 Jul 31
置信度 0.82
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Flavonoids, prominent bioactive compounds in citrus fruits, exhibit diverse health-promoting properties. However, the dynamic compositional changes in flavonoids during fruit development remain insufficiently characterized in Citrus reticulata 'Shiyue Ju' (STJ…
pubmed
Guan Q, Huang D, Zhang L, Lv Z
2026 Jul 29
置信度 0.82