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Cell-fate decisions involve coordinated genome-wide expression changes, typically leading to a limited number of phenotypes. Although often modeled as simple toggle switches, these rather simplistic representations often disregard the complexity of regulatory …
openalex
Kishore Hari, Pradyumna Harlapur, Aashna Saxena, Kushal Haldar 等
2025-01-02
置信度 0.72
Curse of dimensionalityProperty (philosophy)Space (punctuation)ChemistryComputer science
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Materials able to sense and respond to external stimuli by adapting their internal state to process and store information, represent promising candidates for implementing neuromorphic functionalities and brain-inspired computing paradigms. In this context, neu…
openalex
Federico Ferrarese Lupi, Mateo Rosero‐Realpe, Antonio Ocarino, Francesca Frascella 等
2025-05-13
置信度 0.72
Neuromorphic engineeringComputer scienceReservoir computingContext (archaeology)Materials science
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Nonoccupational postexposure prophylaxis (nPEP) for HIV is recommended when a nonoccupational (e.g., sexual, needle, or other) exposure to nonintact skin or mucous membranes that presents a substantial risk for HIV transmission has occurred, and the source has…
openalex
Mary R. Tanner, Jesse O’Shea, Katrina M Byrd, Marie Johnston 等
2025-05-06
置信度 0.72
Human immunodeficiency virus (HIV)Injection drug useDrugMedicinePre-exposure prophylaxis
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Abstract The brain orchestrates complex physiological processes through intricate neural networks, with synapses serving as the fundamental units for inter‐neuronal communication and ensuring the efficient functioning of these networks. Consequently, the devel…
openalex
Weiwei Li, Chunbo Duan, Ying Wei, Hui Xu
2025-09-23
置信度 0.72
MemristorNeuromorphic engineeringEmulationComputer scienceArtificial neural network
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High value and long life products require continuous maintenance throughout their life cycle to achieve required performance with optimum through-life cost. This paper presents foundations and technologies required to offer the maintenance service. Component a…
openalex
Rajkumar Roy, Rainer Stark, Kirsten Tracht, Shozo Takata 等
2016-01-01
置信度 0.72
EngineeringSystems engineeringManufacturing engineeringConstruction engineeringComputer science
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The European Society of Endodontology and the American Association for Endodontists have released position statements and clinical considerations for regenerative endodontics. There is increasing literature on this field since the initial reports of Iwaya et a…
openalex
S. G. Kim, Matthew Malek, Ásgeir Sigurðsson, Louis M. Lin 等
2018-05-19
置信度 0.72
EndodonticsDentistryMedicineTraumatologyPlatelet-rich fibrin
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The "River Publishers Series in Information Science and Technology" covers research which ushers the 21st Century into an Internet and multimedia era.Multimedia means the theory and application of filtering, coding, estimating, analyzing, detecting and recogni…
openalex
Leandro Soares, Piotr Dziurzański, Amit Kumar Singh
2016-01-01
置信度 0.72
Cloud computingComputer scienceResource allocationDistributed computingResource (disambiguation)
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Background: Predicting endoscopic remission is crucial for optimizing clinical treatment strategies and switching biologics in Crohn's disease (CD). Mucosal healing (MH) is a key therapeutic target. This study aimed to develop a clinically applicable predictio…
openalex
Linlin Huang, Hui Li, Shuo Wang, Ying Ren
2025-05-23
置信度 0.72
NomogramMedicineRadiomicsCohortInternal medicine
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Extracts of medicinal seeds can be used to synthesize nanoparticles (NPs) in more environmentally friendly ways than physical or chemical ways. For the first time, aqueous extract from unexploited grape seeds was used in this study to create Se/ZnO NPS utilizi…
openalex
Samy Selim, Amna A. Saddiq, Ruba A. Ashy, Afra Mohammed Baghdadi 等
2025-01-02
置信度 0.72
Bimetallic stripSeleniumZincNanoparticleNanotechnology
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Cortisone is a metabolite belonging to the corticosteroid class that is used pharmaceutically directly as a drug or prodrug. In addition to its large consumption, its use is linked to several side effects, so pharmaceutical research aims to develop effective d…
openalex
Stefania Costa, Paola Tedeschi, Luca Ferraro, Sarah Beggiato 等
2022-11-24
置信度 0.72
BiotransformationCortisonePharmacologyChemistryProdrug
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Hematologic adverse events are common dose-limiting toxicities in drug development. Classical animal models for preclinical safety assessment of immunotherapies are often limited due to insufficient cross-reactivity with non-human homologous proteins, immune s…
openalex
Leopold Koenig, Laurent Juglair, Thi Phuong Tao, Susanne Fischer 等
2025-05-15
置信度 0.72
Profiling (computer programming)DrugDrug developmentMicrofluidicsBone marrow
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Computer numerically controlled (CNC) milling has been one of the most commonly used manufacturing processes for the performance of multiple operations, from tiny integrated circuits to heavy-duty mining machine gearboxes. It is a well-known machining process …
openalex
Serge Balonji, Lagouge K. Tartibu, Imhade P. Okokpujie
2023-03-24
置信度 0.72
Soft computingSurface roughnessMachiningArtificial neural networkNumerical control
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Summary Global change and emerging concepts in ecology and evolution are leading to a growing interest in phenotypic plasticity (PP), the environmentally contingent trait expression observed in a given genotype. The need to quantify PP in a simple manner in co…
openalex
Fernando Valladares, David Sánchez‐Gómez, Miguel Á. Zavala
2006-09-14
置信度 0.72
Phenotypic plasticityTraitBiologyEcologyEstimation
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In the past few decades, polymeric nanocarriers have been recognized as promising tools and have gained attention from researchers for their potential to efficiently deliver bioactive compounds, including drugs, proteins, genes, nucleic acids, etc., in pharmac…
openalex
Sabya Sachi Das, Priyanshu Bharadwaj, Muhammad Bilal, Mahmood Barani 等
2020-06-22
置信度 0.72
NanocarriersNanomedicineNanotechnologyMaterials scienceBiodistribution
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Abstract Soil biology is vital for maintaining productivity, enhancing soil health, and creating resilient agroecosystems. However, many questions remain on how microbial communities are impacted by different soil properties and management practices, especiall…
openalex
Benjamin K. Agyei, Christine D. Sprunger, Eric K. Anderson, Christina Curell 等
2024-02-19
置信度 0.72
Soil healthTillageAgronomySoil biologyAgroecosystem
-
Emerging evidence suggests the gut microbiome's potential in predicting response to biologic treatments in patients with inflammatory bowel disease (IBD). In this prospective study, we aimed to predict treatment response to vedolizumab and ustekinumab, integra…
openalex
Femke M. Prins, Iwan J. Hidding, Marjolein A. Y. Klaassen, Valerie Collij 等
2024-08-21
置信度 0.72
MicrobiomeMetabolomeMetagenomicsInflammatory bowel diseaseVedolizumab
-
Abstract Social computing broadly refers to supporting social behaviours using computational systems. In the last decade, the advent of Web 2.0 and its social networking services, wikis, blogs, and social bookmarking has revolutionised social computing, creati…
openalex
Licia Capra, Daniele Quercia
2011-11-22
置信度 0.72
Social computingComputer scienceBookmarkingWorld Wide WebMiddleware (distributed applications)
-
Peripheral facial paralysis is the dominant treatment disease of acupuncture. A large number of studies have proved the effectiveness of acupuncture in the treatment of peripheral facial paralysis. However, the underlying biological effect remains in an explor…
openalex
Wenwen Duan, Dan Chen, Zubo Huang, Yue Zeng 等
2025-04-24
置信度 0.72
AcupunctureMedicineFacial paralysisPeripheralFacial nerve
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Today’s crystal engineering in coordination chemistry community offers diverse applications and innovative bonding concepts in crystal assembly. The current research delves into synthesizing one novel Cu(II) complex, [(NO 3 )Cu(H 2 O)(L 2,2−Me2 )( μ -H 2 O)Cu(…
openalex
Dhrubajyoti Majumdar, Jessica Elizabeth Philip, Sourav Roy, Bouzid Gassoumi 等
2025-07-30
置信度 0.72
Schiff basePerchlorateCharacterization (materials science)ChemistryCombinatorial chemistry
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This study addresses a critical gap in concrete strength prediction by conducting a comparative analysis of three deep learning algorithms: convolutional neural networks (CNNs), gated recurrent units (GRUs), and long short-term memory (LSTM) networks. Unlike p…
openalex
Matiur Rahman Raju, Mahfuzur Rahman, Md Mehedi Hasan, Md. Monirul Islam 等
2023-11-01
置信度 0.72
HyperparameterConvolutional neural networkDeep learningComputer scienceCompressive strength
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Studying species interactions in nature often requires elaborated logistics and intense fieldwork. The difficulties in such task might hinder our ability to answer questions on how biotic interactions change with the environment. Fortunately, a workaround to t…
openalex
Mario R. Moura, Henrique Caldeira Costa, Arthur Diesel Abegg, Esmeralda Alaminos 等
2022-09-04
置信度 0.72
AutotomyArboreal locomotionPredationBiologyEcology
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Abstract Sandy saline soils are widely distributed and commonly experience seasonal or long‐term freezing, yet the freezing process in these soils is rarely studied. This research utilized in situ X‐ray computed tomography (CT) to visualize pore‐scale freezing…
openalex
Xiangbo Gao, Rongrong Tian, Tingchang Yin, S. A. Galindo‐Torres 等
2024-01-30
置信度 0.72
Ice crystalsPore water pressureSoil waterGeologyMineralogy
-
Alzheimer's disease is biologically heterogeneous, and detailed understanding of the processes involved in patients is critical for development of treatments. CSF contains hundreds of proteins, with concentrations reflecting ongoing (patho)physiological proces…
openalex
Betty M. Tijms, Johan Gobom, Lianne M. Reus, Iris E. Jansen 等
2020-09-09
置信度 0.72
Cerebrospinal fluidDiseasePathophysiologyAlzheimer's diseaseAlzheimer's Disease Neuroimaging Initiative
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Purifying extracellular vesicles (EVs) has been challenging because EVs are heterogeneous in cargo yet share similar sizes and densities. Most surface marker-based affinity separation methods are limited to research or diagnostic scales. We report that heparin…
openalex
Yijun Zhou, R Yuan, Allaura S. Cone, Kyle Shifflett 等
2023-06-01
置信度 0.72
Affinity chromatographyExtracellular vesiclesHeparinChemistryMicrovesicles
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Our understanding of most biological systems is in its infancy. Learning their structure and intricacies is fraught with challenges, and often side-stepped in favour of studying the function of different gene products in isolation from their physiological cont…
openalex
Juliane Liepe, Sarah Filippi, Michał Komorowski, Michael P. H. Stumpf
2013-01-31
置信度 0.72
InferenceComputer scienceRobustness (evolution)Systems biologyContext (archaeology)
-
openalex
Céline Mascaux, Triparna Sen, Montse Sánchez‐Céspedes, Sandra Ortiz‐Cuaran 等
2025-06-03
置信度 0.72
MedicineLung cancerTranslational researchCancerLung
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Machine learning has been proposed as an alternative to theoretical modeling when dealing with complex problems in biological physics. However, in this perspective, we argue that a more successful approach is a proper combination of these two methodologies. We…
openalex
Jonathan Martin, M. Mateos, José N. Onuchic, Ivan Coluzza 等
2024-06-24
置信度 0.72
Artificial intelligenceComputer scienceMachine learningInferenceProtein structure prediction
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Purpose Accurate modeling of the relative biological effectiveness (RBE) of particle beams requires increased systematic in vitro studies with human cell lines with care towards minimizing uncertainties in biologic assays as well as physical parameters. In thi…
openalex
Darshana Patel, Lawrence F. Bronk, Fada Guan, C Peeler 等
2017-09-07
置信度 0.72
Linear energy transferMonte Carlo methodRelative biological effectivenessProtonProton therapy
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It is reported that there are approximately 2.2 million bone graft procedures every year due to injuries, bone tumors, marginal bone defects, and aging of the population. However, the scarcity of natural donors and graft rejection make it difficult to adequate…
openalex
Xuewen Ni, Jing Feng, Mengxue Liang, Fangzheng Zhou 等
2025-07-01
置信度 0.72
Composite numberMaterials scienceComposite material
-
The increasing detection of papillary thyroid microcarcinoma (PTMC) has raised concerns regarding overtreatment. For low-risk PTMC, either immediate surgery or active surveillance (AS) can be considered. To facilitate the implementation of AS, the Korean Thyro…
openalex
Eun Kyung Lee, Min Joo Kim, Seung Heon Kang, Bon Seok Koo 等
2025-06-25
置信度 0.72
MedicineGuidelineThyroid carcinomaThyroidLymph node
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The WashU Epigenome Browser (https://epigenomegateway.wustl.edu/) is a web-based tool for exploring genomic data and providing visualization, investigation, and analysis of epigenomic datasets. Since its 2018 update, the redesigned user interface and newly dev…
openalex
Chanrung Seng, Shane Liu, Wenjin Zhang, Xiaoyu Zhuo 等
2025-05-05
置信度 0.72
CodebaseEpigenomeGenome browserComputer scienceData visualization
-
Abstract The term diffusive media refers to all the media for which the photon diffusion equation provides an accurate description of light propagation. Indeed, this is the case for a plethora of natural media, such as biological tissues and agricultural produ…
openalex
Rebecca Re, Lorenzo Spinelli, Fabrizio Martelli, Laura Di Sieno 等
2025-03-01
置信度 0.72
Domain (mathematical analysis)Computer scienceTime domainOpticsPhysics
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Large-scale single-cell analyses are of fundamental importance in order to capture biological heterogeneity within complex cell systems, but have largely been limited to RNA-based technologies. Here we present a comprehensive benchmarked experimental and compu…
openalex
Erwin M. Schoof, Benjamin Furtwängler, Nil Üresin, Nicolas Rapin 等
2021-06-07
置信度 0.72
WorkflowProteomicsComputer scienceComputational biologyHierarchy
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Rapid development and wide adoption of mass spectrometry-based glycoproteomic technologies have empowered scientists to study proteins and protein glycosylation in complex samples on a large scale. This progress has also created unprecedented challenges for in…
openalex
Yingwei Hu, Michael Schnaubelt, Li Chen, Bai Zhang 等
2024-06-13
置信度 0.72
Cloud computingComputer sciencePipeline (software)SoftwareDatabase
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Human cancer cells overexpress many peptide receptors as molecular targets. Radiolabeled peptides that bind with high affinity and specificity to the receptors on tumor cells hold great potential for both diagnostic imaging and targeted radionuclide therapy. T…
openalex
Melpomeni Fani, Helmut R. Maëcke, Subhani M. Okarvi
2012-01-01
置信度 0.72
BombesinPeptideBioconjugationNeurotensinReceptor
-
Predicting the binding affinity of ligands to protein pockets is key in the drug design pipeline. The flexibility of ligand-pocket motifs arises from a range of attractive and repulsive electronic interactions during binding. Accurately accounting for all inte…
openalex
Mirela Puleva, Leonardo Medrano Sandonas, Balázs D. Lőrincz, Jorge Charry 等
2025-09-29
置信度 0.72
van der Waals forceBenchmark (surveying)Computer scienceStatistical physicsFlexibility (engineering)
-
Early secreted antigenic target 6 kDa (ESAT-6) and culture filtrate protein 10 kDa (CFP-10) are complex proteins secreted by Mycobacterium tuberculosis that play a major role in the pathogenesis of tuberculosis. However, studies focusing on the biological func…
openalex
Amira Refai, Meriam Haoues, Houcemeddine Othman, Mohamed‐Ridha Barbouche 等
2015-08-11
置信度 0.72
ESAT-6SecretionRecombinant DNAMycobacterium tuberculosisChemistry
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OBJECTIVES: Carotid plaque vulnerability is a strong predictor of recurrent ipsilateral stroke, but differentiation of plaque components using conventional computed tomography (CT) is suboptimal. The aim of our study was to evaluate the ability of dual-energy …
openalex
Mueez Aizaz, Juul Bierens, Marion J. Gijbels, Tobien H.C.M.L. Schreuder 等
2025-01-21
置信度 0.72
MedicineHounsfield scaleRadiologyCarotid endarterectomyNuclear medicine
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Abstract General reasoning represents a long-standing and formidable challenge in artificial intelligence (AI). Recent breakthroughs, exemplified by large language models (LLMs) 1,2 and chain-of-thought (CoT) prompting 3 , have achieved considerable success on…
openalex
Daya Guo, Dejian Yang, Haowei Zhang, Junxiao Song 等
2025-09-17
置信度 0.72
Computer scienceReinforcement learningArtificial intelligenceVerbal reasoningVerifiable secret sharing
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The field of molecular engineering in medicine has made significant strides in recent years, transforming healthcare, diagnostics, and therapy development. However, the COVID-19 pandemic highlighted the ongoing need for further innovative progress and detailed…
openalex
Zarif Bin Akhtar
2024-06-26
置信度 0.72
Regenerative medicinePerspective (graphical)Data sciencePrecision medicineComputer science
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Abstract Human activities drive a wide range of environmental pressures, including habitat change, pollution and climate change, resulting in unprecedented effects on biodiversity 1,2 . However, despite decades of research, generalizations on the dimensions an…
openalex
François Keck, Tianna Peller, Roman Alther, Cécilia Barouillet 等
2025-03-26
置信度 0.72
BiodiversityHomogenization (climate)EcosystemAquatic biodiversity researchHabitat
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Background: Cerebral edema after large hemispheric infarction is associated with poor functional outcome and mortality. Net water uptake (NWU) quantifies the degree of hypoattenuation on unenhanced-computed tomography (CT) and is increasingly used to measure c…
openalex
Felix Ng, Nawaf Yassi, Gagan Sharma, Scott Brown 等
2022-07-25
置信度 0.72
MedicineModified Rankin ScaleStroke (engine)EdemaMidline shift
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Significance Phosphorylation is essential for life. Phosphorylated molecules play diverse functions in cells, including metabolic (e.g., sugar phosphates), structural (e.g., phospholipids), and instructional (e.g., RNA and DNA). In nature, the phosphorylation …
openalex
Inho Nam, Jae Kyoo Lee, Hong Gil Nam, Richard N. Zare
2017-10-23
置信度 0.72
Sugar phosphatesRibonucleosideChemistryPhosphorylationSugar
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Stroke risk increases with chronological age, but the relationship with biological age (BA) acceleration is poorly understood. We aimed to examine the association between BA acceleration and incident stroke and its subtypes, explore the modifying effects on ge…
openalex
Xuening Zhang, Hao Zhao, Zilin Li, Xinjie Liu 等
2024-12-04
置信度 0.72
Stroke (engine)CohortProspective cohort studyConfoundingIntracerebral hemorrhage
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Hydrogen’s increasing prominence as a sustainable energy carrier point out its transformative potential in the global energy transition. Among the technologies enabling this shift, Proton Exchange Membrane Fuel Cells (PEMFCs) stand out as a vital solution, off…
openalex
Badreddine Kanouni, Abdelbaset Laib, Salah Necaibia, Abdelbasset Krama 等
2025-04-16
置信度 0.72
MetaheuristicComputer scienceBiological systemArtificial intelligenceBiology
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SciPy 2020, the 19th annual Python in Science Conference, was held July 6-12, virtually via the conference platform Crowdcast. Due to the COVID-19 pandemic, the SciPy conference was held online. The SciPy Conference brings together a community of researchers, …
openalex
2020-01-01
置信度 0.72
Python (programming language)Computer scienceLibrary scienceData scienceProgramming language
-
openalex
Jerry D. Wiggert, Raleigh R. Hood, Karl Banse, John C. Kindle
2005-04-30
置信度 0.72
Biogeochemical cycleMonsoonOceanographyEnvironmental scienceForcing (mathematics)
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1 The concept of the ecological niche relates a set of environmental variables to the fitness of species, while habitat suitability models (HSMs) relate environmental variables to the likelihood of occurrence of the species. In spite of this relationship, the …
openalex
Alexandre H. Hirzel, Gwenaëlle Le Lay
2008-07-21
置信度 0.72
NicheEcological nicheEnvironmental niche modellingNiche segregationEcology
-
Background: Ayurveda, the ancient Indian system of medicine, emphasizes personalized holistic care, presenting unique opportunities for integration with Artificial Intelligence (AI). Since 2020, a growing body of research has explored AI applications in Ayurve…
openalex
Srishti Shaumya, R. Mathusoothana S. Kumar
2025-07-01
置信度 0.72
PsychologyData scienceArtificial intelligenceComputer scienceCognitive science
-
Abstract. In a rapidly changing climate, evidence-based decision-making benefits from up-to-date and timely information. We track twelve key sets of indicators of the state of the climate system, closely following Intergovernmental Panel on Climate Change (IPC…
openalex
Piers Forster, Tristram Walsh, Chris Smith, William F. Lamb 等
2026-06-05
置信度 0.72
Greenhouse gasRadiative forcingClimate changeClimate commitmentUnited Nations Framework Convention on Climate Change
-
openalex
Sarah L. C. Giering, Richard Sanders, Richard S. Lampitt, Thomas R. Anderson 等
2014-03-01
置信度 0.72
Abyssal zoneCarbon cycleCarbon sinkOceanographyEnvironmental science
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Abstract In‐sensor computing supports edge computing by reducing data transmission, but logic and arithmetic operations are still underdeveloped in acoustic sensors. Mechanical computing with metamaterials integrates these functions directly into sensors by re…
openalex
Liang Zhang, Ting Tan, Yinghua Chen, Zhimiao Yan
2025-02-21
置信度 0.72
Materials scienceAcoustic sensorSimple programmable logic deviceProgrammable logic deviceAcoustics
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Since early developments in the field of mesoporous materials, mesoporous silica has attracted large interest in drug delivery, as they display an ordered array of pores with diameters ranging from 2 to 50 nm, which can be loaded with drugs. Mesoporous silica …
openalex
Sergio Moya, Raquel Ruiz Hernández, Paula C. Angelomé
2024-09-02
置信度 0.72
Mesoporous materialMesoporous silicaDrug deliveryBiocompatibilityContext (archaeology)
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In this cross-sectional study, we aimed to predict age-related changes in bone microarchitecture and strength at the distal radius (DR) and distal tibia (DT) in 644 Canadian adults (n = 442 women and 202 men) aged 20 to 99 years. We performed a standard morpho…
openalex
Heather Macdonald, Kyle K. Nishiyama, Jian Kang, David A. Hanley 等
2010-07-06
置信度 0.72
Trabecular boneCortical boneQuantitative computed tomographyPopulationMedicine
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Abstract. Bali has been open to tourism since the beginning of the 20th century and is known as the first tourist destination in Indonesia. The Denpasar, Badung, Gianyar, and Tabanan (Sarbagita) areas experience the most rapid growth of tourism activity in Bal…
openalex
Andi Besse Rimba, Tri Atmaja, Geetha Mohan, Saroj Kumar Chapagain 等
2020-08-22
置信度 0.72
TourismLand coverLand useGeographyVegetation (pathology)
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Valorisation des déchets d'équipements électriques et électroniques (DEEE) par différentes approches bio/hydrométallurgiques : application au cas du cuivre et de l’or Le bien-être de notre société dépend directement de plusieurs métaux tels que les métaux comm…
openalex
Arda Isildar
2016-11-18
置信度 0.72
HumanitiesArt
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Although the fifth generation (5G) wireless networks are yet to be fully investigated, the visionaries of the 6th generation (6G) echo systems have already come into the discussion. Therefore, in order to consolidate and solidify the security and privacy in 6G…
openalex
Pawani Porambage, Gürkan Gür, Diana Pamela Moya Osorio, Madhusanka Liyanage 等
2021-01-01
置信度 0.72
Computer scienceComputer securityStandardizationWirelessTelecommunications
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Living systems adopt a diversity of curved and highly dynamic shapes. These diverse morphologies appear on many length scales, from cells to tissues and organismal scales. The common driving force for these dynamic shape changes are contractile stresses genera…
openalex
Gefen Livne, Shachar Gat, Shahaf Armon, Anne Bernheim‐Groswasser
2024-01-04
置信度 0.72
CytoskeletonMyosinActive matterShape changeBiophysics
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Halogens are widely recognized as privileged functionalities for modulating the biological and physicochemical properties of small molecule drugs and have firmly established their place in the medicinal chemist's toolbox.A survey of the literature reveals that…
openalex
Saghir Ali, Cun Zhang, Jia Zhou
2026-02-26
置信度 0.72
ChemistryMEDLINEPharmacologyPoison controlHalogen
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Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis. Its role in atherosclerosis holds great interest because the presence and burden of coronary calcification provide direct evidence of the presence and extent of corona…
openalex
Carlotta Onnis, Renu Virmani, Kenji Kawai, Valentina Nardi 等
2024-01-16
置信度 0.72
MedicineCoronary artery diseaseCalcificationCardiologyStenosis
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Abstract Research on optoelectronic synapses that can integrate both detection and processing functions is essential for the development of efficient neuromorphic computing. Here, we experimentally demonstrated an Ga 2 O 3 ‐based metal–semiconductor–metal (MSM…
openalex
Huazhen Sun, Bingjie Ye, Mei Ge, Biao Gong 等
2025-02-25
置信度 0.72
PhotodetectorNeuromorphic engineeringUltravioletOptoelectronicsMaterials science
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The OECD Review of Fisheries 2025 monitors and analyses fisheries management and support policies in OECD Member countries and other major fishing nations to inform decision makers and help foster sustainable and resilient fisheries that can provide jobs, food…
openalex
OECD
2025-02-03
置信度 0.72
FisheryEnvironmental scienceGeographyOceanographyBiology
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Artificial intelligence (AI) has reached a critical juncture in its integration with healthcare and pharmaceutical developments. Regulatory agencies worldwide are developing frameworks to guide the responsible implementation of AI‐driven drug development and a…
openalex
Sarfaraz K. Niazi
2026-01-01
置信度 0.72
HarmonizationScope (computer science)Regulatory scienceRisk analysis (engineering)Credibility
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The Internet of Medical Things (IoMT) is a vital component of the Internet of Things (IoT), and its importance lies in the urgent need for it and its provision of many medical services, such as examining and monitoring patients in hospitals and their homes. Gi…
openalex
Mishall Al-Zubaidie, Rasha Halim Razzaq
2024-09-02
置信度 0.72
BlockchainInternet of ThingsComputer securityInternet privacyThe Internet
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Over half of the European landscape is under agricultural management and has been for millennia. Many species and ecosystems of conservation concern in Europe depend on agricultural management and are showing ongoing declines. Agri-environment schemes (AES) ar…
openalex
Péter Batáry, Lynn V. Dicks, David Kleijn, William J. Sutherland
2015-05-21
置信度 0.72
Nature ConservationEnvironmental resource managementGeographyEnvironmental planningBusiness
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This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 report focuses primarily on the revised and novel parts of the document. The most significan…
openalex
Claus Vogelmeier, Gerard J. Criner, Fernando J. Martínez, Antonio Anzueto 等
2017-03-01
置信度 0.72
MedicineObstructive lung diseaseCOPDIntensive care medicinePulmonary disease
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Nanoparticles are currently used for cancer theranostics in the clinical field. Among nanoparticles, gold nanoparticles (AuNPs) attract much attention due to their usability and high performance in imaging techniques. The wide availability of biological precur…
openalex
Saman Sargazi, Ushna Laraib, Simge Er Zeybekler, Abbas Rahdar 等
2022-03-27
置信度 0.72
Colloidal goldNanotechnologyNanocarriersNanomedicineMaterials science
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openalex
Thomas E. Marshall, Tiffiany Champagne-Langabeer, Darla M. Castelli, Deanna M. Hoelscher
2017-11-01
置信度 0.72
Cognitive computingComputer scienceArtificial intelligenceCognitionData science
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Abstract Quantum computers use the properties of quantum physics to perform information storage and processing operations. The operation of these computers involves concepts such as entanglement and superposition, which endow them with a great processing power…
openalex
Kleber Xavier Sampaio de Souza, Édson Luís Bolfe, M. A. de A. Leite, Martha Delphino Bambini 等
2024-01-01
置信度 0.72
Current (fluid)AgricultureComputer scienceQuantum computerEnvironmental science
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Human activity depends on the oceans for food, transportation, leisure, and many more purposes. Oceans cover 70% of the Earth’s surface, but most of them are unknown to humankind. This is the reason why underwater imaging is a valuable resource asset to Marine…
openalex
Michele Ferrari, Daniele D’Agostino, Jacopo Aguzzi, Simone Marini
2024-08-12
置信度 0.72
Computer scienceUnderwaterCloud computingPipeline (software)Raw data
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Nanoparticles of Zinc oxide (ZnONPs), has a variety of applications such as antibacterial property, water treatment for pollutant removal, and as catalysts for organic reactions etc. and have been synthesized utilizing a variety of approaches, including green …
openalex
Jaya Gangwar, Balamuralikrishnan Balasubramanian, Akshay Pratap Singh, Arun Meyyazhagan 等
2023-07-29
置信度 0.72
ZincNuclear chemistryAntibacterial activityPhotocatalysisNanoparticle
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Biological nanopores enable the electrical detection of biomolecules, making them ideal sensors for use in health-monitoring devices. Proteins are widely recognized as biomarkers for various diseases, but they present a unique challenge due to their vast diver…
openalex
Sabine Straathof, Giovanni Di Muccio, Giovanni Maglia
2025-04-22
置信度 0.72
ChemistryNanoporeSample (material)NanotechnologyChromatography
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Abstract Reservoir computing (RC), a type of recurrent neural network, is particularly well‐suited for hardware implementation in edge computing. It is shown that RC hardware based on dynamic memristors potentially offers much lower power consumption and reduc…
openalex
Zelin Ma, Jun Ge, Shusheng Pan
2024-08-21
置信度 0.72
MemristorMaterials scienceReservoir computingNanotechnologyElectronic engineering
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Coronary artery calcium (CAC) is a marker of subclinical atherosclerosis that confers increased risk of atherosclerotic cardiovascular disease. Measured by noncontrast cardiac computed tomography, CAC improves risk stratification beyond traditional risk factor…
openalex
Randi E. Foraker, Laurence Sperling, Lisa C. Bratzke, Matthew J. Budoff 等
2025-10-16
置信度 0.72
MedicineCoronary artery calciumSubclinical infectionCoronary artery diseaseDisease
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To evaluate the diagnostic value of computer cavernosography (CT cavernosography) in erectile dysfunction (ED) with a description of the technical aspects of the method.
pubmed
Kyzlasov P S, Mustafayev A T, Bashkov A N, Abuev G G 等
2025 Dec
置信度 0.82
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The precise application of stereotactic body radiation therapy (SBRT) for prostate cancer is challenged by prostate motion and anatomical variations in surrounding organs such as the bladder and rectum. Online adaptive radiotherapy (oART) using cone beam compu…
pubmed
Gáldi Á, Ágoston P, Pesznyák C, Takácsi-Nagy Z 等
2026 Jul 7
置信度 0.82
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Reliable evaluation of edible oil quality is essential for ensuring consumer safety and detecting market adulteration. This study presents a rapid and non-destructive approach that integrates Fourier Transform Infrared (FTIR) spectroscopy with chemometric and …
pubmed
Varma SO, Jadhav PP, Vishwakarma AL, Sonawane MR 等
2026 Dec 15
置信度 0.82
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Polymerase chain reaction (PCR) enables rapid, cost-effective diagnostics but requires prior identification of genomic regions that allow sensitive and specific detection of target microbial groups, herein referred to as microbial signature sequences. We intro…
pubmed
Wang MX, Kille B, Nute MG, Zhou S 等
2026 Jul 1
置信度 0.82
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Active learning has emerged as an effective strategy for accelerating molecular discovery under limited labeling budgets. However, existing methods primarily focus on global information, often overlooking activity cliff-sharp changes in bioactivity caused by s…
pubmed
Kim J, Kim Y, Koo B, Bang D 等
2026 Jul 1
置信度 0.82
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Accurate prediction of drug response in precision medicine requires models that capture how specific chemical substructures interact with cellular pathway states. However, most existing deep learning approaches treat chemical and transcriptomic modalities inde…
pubmed
Han Y, Kim S, Jeong E, Lee S 等
2026 Jul 1
置信度 0.82
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Physically associated bacterial groups can enhance resilience through emergent traits, including access to inaccessible substrates, increased stress tolerance, and reduced predation. These traits arise from physical and chemical interactions between cells and …
pubmed
Day TC, Schwartzman JA
2026 Jul 14
置信度 0.82
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Precision oncology relies on accurately distinguishing patient-specific driver mutations from the vast background of passenger alterations. While graph-based computational methods have emerged as powerful tools for this task, they often struggle to preserve th…
pubmed
Cho SP, Cho YR
2026 Jul 1
置信度 0.82
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Reference genome assemblies are essential infrastructure for investigating phylogeny and population/conservation genetics of wild organisms. Birds serve as model vertebrates in ecology and evolutionary biology due to their well-documented natural histories and…
pubmed
Øksnebjerg DB, Nielsen SD, Chen G, Andersen MJ 等
2026 Jan 21
置信度 0.82
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This systematic review and meta-analysis was registered with PROSPERO (Registration No. CRD420251130849) and conducted in accordance with PRISMA 2020 guidelines. A comprehensive literature search of PubMed, Web of Science, and SciencDirect (2000-2025) identifi…
pubmed
Ahuja R, Sharma K, Kumar Tiwari A, Uttam V 等
2026 Jul 7
置信度 0.82
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We revise the molecular variation and taxonomy of an assemblage of lineages of endemic Malagasy cophyline microhylid frogs, previously considered to be allied to Platypelis tetra. Based on DNA sequences obtained from the P. tetra holotype via a museomics appro…
pubmed
Rakotoarison A, Petzold A, Scherz MD, Crottini A 等
2025 Nov 6
置信度 0.82
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Centaurea is a large genus of approximately 700 species, predominantly distributed across the Mediterranean region and Western Asia, that has been empirically used since ancient times for metabolic, inflammatory, hepatic, infectious, and neurological disorders…
pubmed
Reda EH, Mohamed TA, Abdel Shakour ZT, El-Halawany AM 等
2026 Jul
置信度 0.82
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Lipid packing is a fundamental characteristic of bilayer membranes. Yet, we lack detailed mechanistic understanding of how lipid packing directly affects membrane-associated cellular processes. Here, we address this by focusing on caveolae, small Ω-shape…
pubmed
Larsson E, Kabedev A, Pace H, Lindwall J 等
2026 Jul 6
置信度 0.82
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While pharmacogenetic testing has traditionally relied on array-based genotyping platforms, these methods are limited by incomplete variant coverage and inability to detect novel alleles. We hypothesize that the performance of genome sequencing (GS) is superio…
pubmed
Numanagić I, Similuk M, Sissung TM, Hari A 等
2026 Jul
置信度 0.82
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Capillary refill time (CRT) has emerged as a validated resuscitation target in acute circulatory failure following the ANDROMEDA-SHOCK trials and the 2025 ESICM guidelines, yet the physiological mechanisms underlying its clinical utility remain incompletely un…
pubmed
Andrei S, Bar S, Nguyen M, Bouhemad B 等
2026
置信度 0.82
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Cardiovascular disease (CVD) remains the leading cause of global mortality, necessitating a large-scale bioimaging database to advance personalized precision medicine strategies.
pubmed
Ma J, Zhu B, Li J, Zhang X 等
2026 Oct
置信度 0.82
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Ankle sprains are among the most common musculoskeletal injuries, with the anterior talofibular ligament (ATFL) most frequently affected. Although cadaveric and in vivo studies have demonstrated the ATFL's role in restraining anterior talar translation and inv…
pubmed
Minagawa A, Ogihara N, Kubota M, Matsumoto Y 等
2026 Jul
置信度 0.82
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Seasonally migrating animals must navigate environments where resources shift predictably but are increasingly perturbed by climate change and human activities. Empirical work highlights the importance of cognition for these movements, yet the joint roles of p…
pubmed
An Q, Wang X, Baydemir P, Fagan WF 等
2026 Jul 4
置信度 0.82
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In December 2025, the Advisory Committee on Immunization Practices recommended individual-based decision-making-termed shared clinical decision-making (SCDM) on CDC schedules-for hepatitis B (HepB) birth-dose vaccination in infants of mothers documented as HBs…
pubmed
Yang YT
2026 Dec
置信度 0.82
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Growth hormone secretagogue receptors (GHSRs) modulate reward and cost processing separately, but their role in conflict-based decision-making is unclear. We observed dose-dependent effects of the GHSR agonist ibutamoren (IBU) on rat decision-making performanc…
pubmed
Salcido AA, Reyes NF, Macias AY, Batson SA 等
2026 Jun 25
置信度 0.82
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Electrocorticography uses non-penetrating electrodes embedded in flexible substrates to record electrical activity from the surface of the brain. To use the technology to develop minimally invasive, high-bandwidth brain-computer interfaces, it will be necessar…
pubmed
Jung T, Zeng N, Fabbri JD, Eichler G 等
2025 Dec
置信度 0.82
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Vessels encapsulating tumor clusters (VETCs), a CD34-positive vascular pattern in hepatocellular carcinoma (HCC), are linked to aggressive biology, early recurrence, and poor survival. Because pathologic VETC assessment requires postoperative immunohistochemis…
pubmed
Hua X, Fu R, Yin Z
2026 Jul 2
置信度 0.82
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Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants with endocrine-disrupting and carcinogenic effects, but epidemiological evidence linking PFAS exposure to cancer remains inconsistent. We conducted a meta-analysis to systematic…
pubmed
Shen HY, Jin MH, Wu ZC, He TT 等
2026 Sep
置信度 0.82
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Liquid biopsy offers a minimally invasive approach for cancer detection and monitoring, but its diagnostic performance is often limited by low signal abundance and biological noise. Artificial intelligence (AI) has been proposed as a computational framework to…
pubmed
Sisca L, Polito MG, Sisca E, Iuliani M 等
2026
置信度 0.82
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Prenatal alcohol exposure is a major cause of neurodevelopmental and growth impairments collectively termed fetal alcohol spectrum disorders (FASD). However, the mechanisms by which ethanol disrupts early embryonic development remain incompletely understood; f…
pubmed
Lewis LA, Karim MM, Zevallos-Delgado C, Nia MB 等
2026 Jun
置信度 0.82
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The 17th Annual Frontiers in Cancer Science (FCS) conference (2025) highlighted the convergence of multiomics, computational biology, and ancestry-specific genomics to advance proactive cancer care. Key insights included the role of epigenetic plasticity in ma…
pubmed
Huang D, Tee WW, De Mel S, Itahana K 等
2026 Jul 2
置信度 0.82