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OBJECTIVES: RF and ACPA are used as diagnostic tools and their presence has been associated with clinical response to some biologic DMARDs (bDMARDs) in RA. This study compared the impact of seropositivity on drug discontinuation and effectiveness of bDMARDs in…
openalex
Delphine S. Courvoisier, Katerina Chatzidionysiou, Denis Mongin, Kim Lauper 等
2020-06-10
置信度 0.72
MedicineBiologic AgentsImmunologyFamily medicineRheumatoid arthritis
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The purpose of this review is to examine whether a contribution of social exclusion to the pathogenesis of psychosis is compatible with the dopamine hypothesis and/or the neurodevelopmental hypothesis. Humans experience social exclusion as defeating. An animal…
openalex
Jean‐Paul Selten, Jan Booij, Bauke Buwalda, Andreas Meyer‐Lindenberg
2016-12-08
置信度 0.72
DopaminePsychosisPrefrontal cortexNeuroscienceNucleus accumbens
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A major focus of current biological studies is to fill the knowledge gaps between cell, tissue and organism scales. To this end, a wide array of contemporary optical analytical tools enable multiparameter quantitative imaging of live and fixed cells, three-dim…
openalex
Ruslan I. Dmitriev, Xavier Intes, Margarida Barroso
2021-05-01
置信度 0.72
Förster resonance energy transferLuminescenceBiological imagingFluorescence-lifetime imaging microscopyFluorescence
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Changes in the chemical environment can trigger large motions in chemomechanical polymers. The unique feature of such intelligent materials, mostly in the form of hydrogels, is therefore, that they serve as sensors and actuators at the same time, and do not re…
openalex
Hans‐Jörg Schneider, Kazuaki Kato, Robert M. Strongin
2007-08-27
置信度 0.72
Covalent bondPolymerSelf-healing hydrogelsEffectorChemistry
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Dose-response analysis can be carried out using multi-purpose commercial statistical software, but except for a few special cases the analysis easily becomes cumbersome as relevant, non-standard output requires manual programming. The extension package drc for…
openalex
Christian Ritz, Florent Baty, J. C. Streibig, Daniel Gerhard
2015-12-30
置信度 0.72
Computer scienceR packageStatistical analysisSoftwareStatistical inference
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BACKGROUND AND PURPOSE: Magnetic resonance perfusion (MRP) and computed tomographic perfusion (CTP) are being increasingly applied in acute stroke trials and clinical practice, yet the comparability of their perfusion values is not well validated. The aim of t…
openalex
Longting Lin, Andrew Bivard, Christopher Levi, Mark Parsons
2014-05-14
置信度 0.72
MedicinePerfusionConcordancePerfusion scanningStroke (engine)
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openalex
Elspeth F. Garman, Martin H. Weik
2023-08-11
置信度 0.72
Radiation damageMacromoleculeElectron microscopeCryo-electron microscopyDiffraction
-
openalex
Yu.A. Ovchinnikov
1974-08-15
置信度 0.72
Bioorganic chemistryLibrary scienceCitationChemistryFunction (biology)
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Asthma is a common chronic inflammatory condition of the airways that affects about 350 million people globally. In 5%-10% of individuals, it is severe, with considerable morbidity and high health care utilization. The goal of asthma management is disease cont…
openalex
Peer Ameen Shah, Christopher E. Brightling
2023-05-24
置信度 0.72
MedicineAsthmaIntensive care medicineDiseaseImmunology
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The timely diagnosis of prosthetic heart valve endocarditis remains challenging yet of utmost importance. 18F-fluorodeoxyglucose (18 F-FDG) positron emission/computed tomography (PET/CT) and cardiac computed tomography angiography (CTA) were recently introduce…
openalex
Laurens E. Swart, Asbjørn M. Scholtens, Wilco Tanis, Koen Nieman 等
2017-12-17
置信度 0.72
MedicineEndocarditisPositron emission tomographyRadiologyInfective endocarditis
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Abstract Neuromorphic algorithms achieve remarkable performance milestones in tasks where humans have traditionally excelled. The breadth of data generated by these paradigms is, however, unsustainable by conventional computing chips. In-memory computing hardw…
openalex
Wen Zhou, Nikolaos Farmakidis, Johannes Feldmann, Xuan Li 等
2022-05-01
置信度 0.72
Computer sciencePhotonicsNeuromorphic engineeringEfficient energy useComputer architecture
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Abstract. Rivers are a major source of nutrients, carbon and alkalinity to the global ocean. In this study, we firstly estimate pre-industrial riverine loads of nutrients, carbon and alkalinity based on a hierarchy of weathering and terrestrial organic matter …
openalex
Fabrice Lacroix, Tatiana Ilyina, Jens Hartmann
2020-01-06
置信度 0.72
AlkalinityEnvironmental scienceNutrientBiogeochemical cycleSink (geography)
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Abstract. Accurate assessment of anthropogenic carbon dioxide (CO2) emissions and their redistribution among the atmosphere, ocean, and terrestrial biosphere in a changing climate is critical to better understand the global carbon cycle, support the developmen…
openalex
Pierre Friedlingstein, Michael O’Sullivan, Matthew W. Jones, Robbie M. Andrew 等
2025-11-13
置信度 0.72
BiosphereEnvironmental scienceGreenhouse gasCarbon cycleClimate change
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Abstract Automated deployment and run-time management of microservices-based applications in cloud computing environments is relatively well studied with several mature solutions. However, managing such applications and tasks in the cloud-to-edge continuum is …
openalex
Amjad Ullah, Huseyin Dagdeviren, Resmi C. Ariyattu, James DesLauriers 等
2021-11-02
置信度 0.72
MicroservicesCloud computingComputer scienceOrchestrationEdge computing
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G protein-coupled receptors (GPCRs) are membrane-spanning transducers mediating the actions of numerous physiological ligands and drugs. The GPCR database GPCRdb supports a large global research community with reference data, analysis, visualization, experimen…
openalex
Luis P Taracena Herrera, Søren Norge Andreassen, Jimmy Caroli, Ismael Rodríguez‐Espigares 等
2024-11-18
置信度 0.72
BiologyLigand (biochemistry)Similarity (geometry)Computational biologyStructural similarity
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Alzheimer’s disease (AD) is a neurodegenerative disorder mostly influencing the elderly, and causes death due to dementia. The main pathogenic feature connected with the progression of this multifactorial disease is the weakening of the cholinergic system in t…
openalex
Weiam Hussein, Begüm Nurpelin Sağlık, Serkan Levent, Büşra Korkut 等
2018-08-14
置信度 0.72
ButyrylcholinesteraseAcetylcholinesteraseCholinesteraseCholinergicPharmacology
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The TreeNet research and monitoring network has been continuously collecting data from point dendrometers and air and soil microclimate using an automated system since 2011. The goal of TreeNet is to generate high temporal resolution datasets of tree growth an…
openalex
Roman Zweifel, Sophia Etzold, David Basler, Reinhard Bischoff 等
2021-11-04
置信度 0.72
Tree (set theory)Computer scienceOutlierMicroclimateTemporal resolution
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Masatoshi Nei, Takeo Maruyama, Ranajit Chakraborty; THE BOTTLENECK EFFECT AND GENETIC VARIABILITY IN POPULATIONS, Evolution, Volume 29, Issue 1, 1 March 19
openalex
Masatoshi Nei, Takeo Maruyama, Ranajit Chakraborty
1975-03-01
置信度 0.72
PopulationPopulation geneticsDemographyLibrary scienceGenealogy
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This paper compares modeled biotic and physical effects on intertidal sediment transport, using parameterizations that are based on laboratory and field experiments. A one‐dimensional model of an intertidal transect is constructed. The model is aligned cross s…
openalex
Rose Wood, J. Widdows
2002-05-01
置信度 0.72
Intertidal zoneSedimentDeposition (geology)Sedimentary budgetTransect
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Background A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-1…
openalex
Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi, Lily Yin Weckx 等
2020-12-08
置信度 0.72
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakInterimMedicine
-
openalex
A. J. Simmons, Jean-Louis Fellous, V. Ramaswamy, Kevin E. Trenberth 等
2016-03-24
置信度 0.72
Earth system scienceProcess (computing)Earth observationSystems engineeringPredictability
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BACKGROUND: Antimicrobial resistance (AMR) poses an important global health challenge in the 21st century. A previous study has quantified the global and regional burden of AMR for 2019, followed with additional publications that provided more detailed estimat…
openalex
Mohsen Naghavi, Stein Emil Vollset, Kevin S Ikuta, Lucien R Swetschinski 等
2024-09-01
置信度 0.72
Antibiotic resistanceAntimicrobialMedicineEnvironmental healthMicrobiology
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Early childhood growth has many downstream effects on future health and reproduction and is an important measure of offspring quality. While a tradeoff between family size and child growth outcomes is theoretically predicted in high-fertility societies, empiri…
openalex
Karen L. Kramer, Amanda Veile, Erik Otárola‐Castillo
2016-03-03
置信度 0.72
Competition (biology)SiblingBiologyEvolutionary biologyEcology
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Standard treatment for bone defects is the biological reconstruction using autologous bone-a therapeutical approach that suffers from limitations such as the restricted amount of bone available for harvesting and the necessity for an additional intervention th…
openalex
Maria Karadjian, Christopher Essers, Stefanos Tsitlakidis, Bruno Reible 等
2019-01-14
置信度 0.72
Bioactive glassCalciumMaterials scienceComposite numberIn vivo
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Fungi play major roles in ecosystem processes, but the determinants of fungal diversity and biogeographic patterns remain poorly understood. Using DNA metabarcoding data from hundreds of globally distributed soil samples, we demonstrate that fungal richness is…
openalex
Leho Tedersoo, Mohammad Bahram, Sergei Põlme, Urmas Kõljalg 等
2014-11-28
置信度 0.72
EdaphicSpecies richnessFungal DiversityEcologyDiversity (politics)
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Single photon emission computed tomography (SPECT) and positron emission tomography (PET) are now being used to improve the information available from radioisotopic imaging of patients with cancer. These nuclear medicine techniques offer the potential for stud…
openalex
Robert E. Coleman
1991-02-15
置信度 0.72
Positron emission tomographyNuclear medicineEmission computed tomographySpect imagingMedicine
-
openalex
Jerry P. Nolan, Claudio Sandroni, Alain Cariou, Tobias Cronberg 等
2025-10-01
置信度 0.72
MedicineResuscitationIntensive careCardiopulmonary resuscitationMedical emergency
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Importance: Older age may be accompanied by changes in the pharmacokinetics or pharmacodynamics or both of medications that can result in altered safety and efficacy profiles. Objective: To assess representation of older adults in clinical trials of new drug a…
openalex
Sandra Lau, Yue Huang, Julie Hsieh, Shenggang Wang 等
2022-10-14
置信度 0.72
MedicineClinical trialPopulationInternal medicineEnvironmental health
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Despite refinements in surgical techniques for liver transplantation, liver size disparity remains one of the most common problems in pediatric patients. Optimal liver graft size remains unknown and the volume of diseased liver in the recipient is not indicati…
openalex
Koichi Urata, Seiji Kawasaki, Hidetoshi Matsunami, Yasuhiko Hashikura 等
1995-05-01
置信度 0.72
Liver transplantationBody surface areaMedicineBody weightLiver disease
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Post-translational modifications (PTMs) are essential for modulating protein function and influencing stability, activity and signaling processes. The dbPTM 2025 update significantly expands the database to include over 2.79 million PTM sites, of which 2.243 m…
openalex
Chia‐Ru Chung, Yun Tang, Yen-Peng Chiu, Shangfu Li 等
2024-11-11
置信度 0.72
Translational researchBiologyResource (disambiguation)Computational biologyFunction (biology)
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Abstract Brain‐inspired (neuromorphic) computing that offers lower energy consumption and parallelism (simultaneous processing and memorizing) compared to von Neumann computing provides excellent opportunities in many computational tasks ranging from image rec…
openalex
Jinxin Li, Priyanka Dwivedi, Kowsik Sambath Kumar, Tania Roy 等
2020-11-05
置信度 0.72
Neuromorphic engineeringMaterials scienceOptoelectronicsPhotonicsCarbon nanotube
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Summary Recent years have seen an explosive growth in the amount of biochemical data available. Numerous databases have been established and are being used as an essential resource by biologists around the world. The sheer amount and heterogeneity of these dat…
openalex
Jan Küntzer, Torsten Blum, Andreas Gerasch, Christina Backes 等
2006-12-01
置信度 0.72
Computer scienceJavaRelational databaseData warehouseVisualization
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Organic chemists are able to synthesize molecules in greater number and chemical complexity than ever before. Yet, a majority of these compounds go untested in biological systems, and those that do are often tested long after the chemist can incorporate the re…
openalex
Christopher J. Gerry, Bruce K. Hua, Mathias J. Wawer, Jonathan P. Knowles 等
2016-07-11
置信度 0.72
ChemistryDrug discoveryProfiling (computer programming)AnnotationCombinatorial chemistry
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BACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of global mortality. Understanding epidemiologic trends in the modifiable risk factors driving CVDs is essential in designing effective countermeasures. OBJECTIVES: The aim of this study was to f…
openalex
Bryan Chong, Jayanth Jayabaskaran, Silingga Metta Jauhari, Jobelle Chia 等
2025-07-01
置信度 0.72
MedicineSyndemicEnvironmental healthPublic healthNursing
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Abstract The properties of both inorganic and organic materials and the function of biological structures can often only be understood by analyzing them simultaneously on atomic and nanoscopic, if not mesoscopic, scale. Here, the problem arises to render milli…
openalex
Norbert Lindow, Daniel Baum, Hans‐Christian Hege
2012-06-01
置信度 0.72
Mesoscopic physicsExploitRendering (computer graphics)Nanoscopic scaleComputer science
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Accurate estimation of the contrast transfer function (CTF) is critical for a near-atomic resolution cryo electron microscopy (cryoEM) reconstruction. Here, a GPU-accelerated computer program, Gctf, for accurate and robust, real-time CTF determination is prese…
openalex
Kai Zhang
2015-11-20
置信度 0.72
Computer science
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MODOMICS is the reference database of RNA modifications and related information, integrating chemical, biochemical, structural, and functional data. In this 2025 update, marking the 20th anniversary of MODOMICS, the database has been significantly expanded in …
openalex
Dominik Sordyl, Etienne Boileau, Agata Bernat, S. Maiti 等
2025-11-24
置信度 0.72
BiologyRNAComputational biologyScope (computer science)Similarity (geometry)
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The data resources provided by the European Bioinformatics Institute (EMBL-EBI) cover major areas of biological and biomedical research, giving free and open access to users ranging from expert to casual level. The EBI Search engine provides a unified metadata…
openalex
M. B. Y. D. J. Pearce, Prasad Basutkar, Renato Caminha Juaçaba Neto, Vijay Venkatesh Subramoniam 等
2025-05-05
置信度 0.72
MetadataWorld Wide WebBiologyInterface (matter)Search engine
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Microplastics have been extensively documented in marine ecosystems and food webs with devastating impacts. To solve this global crisis, identifying the polymer composition is key for resolving the material origin, geographic source, and ecosystem life cycle o…
openalex
Emily A. Miller, Kevan M. Yamahara, Chris French, Neil E. Spingarn 等
2022-12-24
置信度 0.72
Marine ecosystemMarine lifeMicroplasticsEnvironmental scienceTrophic level
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A correction has been published: European Heart Journal, ehaa895, https://doi.org/10.1093/eurheartj/ehaa895
openalex
Jean‐Philippe Collet, Hölger Thiele, Emanuele Barbato, Olivier Barthélémy 等
2020-07-10
置信度 0.72
MedicineElevation (ballistics)Acute coronary syndromeInternal medicineCardiology
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Peripheral quantitative computed tomography provides an automatical scan analysis of trabecular and cortical bone compartments, calculating not only their bone mineral density (BMD), but also bone geometrical parameters, such as marrow and cortical Cross-Secti…
openalex
Stefano Stagi, Loredana Cavalli, Tiziana Cavalli, Maurizio de Martino 等
2016-09-26
置信度 0.72
Quantitative computed tomographyMedicineDensitometryCortical boneBone mineral
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openalex
Símone Rossi, Mark Hallett, Paolo Maria Rossini, Álvaro Pascual‐Leone
2009-10-15
置信度 0.72
Transcranial magnetic stimulationNeuroimagingBrain stimulationMedicineMagnetic resonance imaging
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Cardiac imaging is central to the diagnosis and risk stratification of coronary artery disease, beyond symptoms and clinical risk factors, by providing objective evidence of myocardial ischaemia and characterisation of coronary artery plaque. CT coronary angio…
openalex
Keith M. Channon, David E. Newby, Edward Nicol, John Deanfield
2022-01-12
置信度 0.72
MedicineCoronary artery diseaseCardiologyInternal medicineFractional flow reserve
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Advances in neurotechnologies are reigniting opportunities to bring neural computation insights into broader computing applications.
openalex
James B. Aimone
2019-03-20
置信度 0.72
Computer scienceAlgorithmMoore's lawOperating system
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Biological biogas upgrading with H2 derived from excess renewable electricity was modeled and simulated in PROII® (AVEVA Group plc, Cambridge, UK). An economic analysis was performed for a biogas plant processing 100,000 tons of biomass (substrate) per year. T…
openalex
Néméhie Lawson, Merlin Alvarado-Morales, Panagiotis Tsapekos, İrini Angelidaki
2021-12-08
置信度 0.72
BiogasRenewable energyBiomass (ecology)BioenergyProfitability index
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This book presents a detailed analysis of the main challenges and opportunities for the computing sector in Brazil over the next decade, from 2025 to 2035. These challenges were identified during the Grand Challenges in Computing Seminar, held in November 2024…
openalex
Sociedade Brasileira de Computação
2025-07-20
置信度 0.72
Computer science
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Propelling energy-constrained sensor tasks to edge servers in Sensor Mobile Edge Computing (SMEC) subjugates Mobile Devices' (MDs) resource limitation menace. Most of the existing studies focused only on the offloading issues. However, a task may hinge on some…
openalex
Sheuli Chakraborty, Kaushik Mazumdar
2022-03-02
置信度 0.72
Computer scienceMobile edge computingServerEnhanced Data Rates for GSM EvolutionTask (project management)
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Physics-informed neural networks (PINNs) have emerged as a transformative methodology integrating deep learning with scientific computing. This review establishes a three-dimensional analytical framework to systematically decode PINNs’ development through meth…
openalex
Zhiyuan Ren, Shijie Zhou, Dong Liu, Qihe Liu
2025-07-21
置信度 0.72
Engineering ethicsManagement sciencePhysicsData scienceComputer science
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While organic farming practices, which are often promoted as models of ecological intensification, generally enhance biodiversity, their effects on the delivery of ecosystem services, such as biological pest control, are still unknown. Here, using a multi-scal…
openalex
Lucile Muneret, Arthur Auriol, Denis Thiéry, Adrien Rusch
2018-11-21
置信度 0.72
Organic farmingAgricultureHabitatBiodiversityIntegrated pest management
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X-ray diffraction/scattering computed tomography (XDS-CT) methods are a non-destructive class of chemical imaging techniques that have the capacity to provide reconstructions of sample cross-sections with spatially resolved chemical information. While X-ray di…
openalex
Naomi Omori, Antonia D. Bobitan, Antonis Vamvakeros, Andrew M. Beale 等
2023-09-11
置信度 0.72
TomographyDiffraction tomographyScatteringDiffractionFocus (optics)
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Supramolecular chemistry is a rapidly evolving field that has focused on building a foundation of fundamental understanding in controlling molecular self-assembly, through the use of non-covalent interactions. A common criticism of the field is that whilst the…
openalex
Dominick E. Balderston, Elba Feo, Anamaria Leonescu, M. F. G. Stevens 等
2025-01-01
置信度 0.72
Supramolecular chemistryNanotechnologyField (mathematics)Engineering ethicsComputer science
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Abstract In a computing context, cybersecurity is undergoing massive shifts in technology and its operations in recent days, and data science is driving the change. Extracting security incident patterns or insights from cybersecurity data and building correspo…
openalex
Iqbal H. Sarker, A. S. M. Kayes, Shahriar Badsha, Hamed Alqahtani 等
2020-07-01
置信度 0.72
Computer scienceContext (archaeology)Data scienceSecurity domainComputer security
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The introduction of the Internet of Things (IoT) and Big Data applications have garnered a massive amount of digital data. Processing and analysing these data demand vast computing resources, proportionately. The major downside of producing and using computing…
openalex
Pijush Kanti Dutta Pramanik, Saurabh Pal, Prasenjit Choudhury
2019-05-02
置信度 0.72
Cloud computingComputer scienceGreen computingGreenhouse gasBig data
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openalex
P. C. W. Davies
2004-11-01
置信度 0.72
CitationReading (process)UniverseCausationLibrary science
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Since May 2022, an outbreak of monkeypox has been ongoing in non-endemic countries. We report four cases in Italy in young adult men reporting condomless sexual intercourse. The patients are in good clinical condition with no need for specific antiviral drugs.…
openalex
Andrea Antinori, Valentina Mazzotta, Serena Vita, Fabrizio Carletti 等
2022-06-02
置信度 0.72
MonkeypoxVirologyTransmission (telecommunications)Sexual transmissionEpidemiology
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MOTIVATION: In the systems biology era, high-throughput omics technologies have enabled the unraveling of the interplay of some biological entities on a large scale (e.g. genes, proteins, metabolites or RNAs). Huge biological networks have emerged, where nodes…
openalex
Maximilian Malek, Rashid Ibragimov, Mario Albrecht, Jan Baumbach
2015-12-14
置信度 0.72
Biological networkComputer scienceComputational biologyBiology
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In this work, we present a cloud-based system for non-contact, real-time recognition and monitoring of physical activities and walking periods within a domestic environment. The proposed system employs standalone Internet of Things (IoT)-based millimeter wave …
openalex
Hajar Abedi, Ahmad Ansariyan, Plinio Pelegrini Morita, Alexander Wong 等
2023-01-09
置信度 0.72
Cloud computingComputer scienceRadarReal-time computingContinuous-wave radar
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Recent high throughput experimental methods have been used to collect large biomedical omics datasets. Clustering of single omic datasets has proven invaluable for biological and medical research. The decreasing cost and development of additional high throughp…
openalex
Nimrod Rappoport, Ron Shamir
2018-09-20
置信度 0.72
Cluster analysisOmicsBenchmark (surveying)Computer scienceData mining
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1. The need to conserve and create linkages among fragmented habitats has given rise to a range of techniques for maximizing connectivity. Methods to identify optimal habitat linkages face trade-offs between constraints on model inputs and biological relevance…
openalex
Sarah C. Sawyer, Clinton W. Epps, Justin S. Brashares
2011-02-23
置信度 0.72
HabitatRelevance (law)Landscape connectivityStrengths and weaknessesEnvironmental resource management
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We propose a regularized, fast, and robust analytical solution for the Q-ball imaging (QBI) reconstruction of the orientation distribution function (ODF) together with its detailed validation and a discussion on its benefits over the state-of-the-art. Our anal…
openalex
Maxime Descoteaux, Elaine Angelino, Shaun Fitzgibbons, Rachid Deriche
2007-08-30
置信度 0.72
Unit sphereRegularization (linguistics)Spherical harmonicsImaging phantomTikhonov regularization
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The study of individuals with autosomal dominant Alzheimer's disease affords one of the best opportunities to characterize the biological and cognitive changes of Alzheimer's disease that occur over the course of the preclinical and symptomatic stages. Unifyin…
openalex
Joshua T. Fox‐Fuller, Alice Cronin‐Golomb, Jennifer R. Gatchel, Daniel Norton 等
2019-04-01
置信度 0.72
DiseaseGeneralizability theoryCohortAlzheimer's diseaseCognition
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The Natural Products Magnetic Resonance Database (NP-MRD; https://np-mrd.org) is a comprehensive, freely accessible, web-based resource for the deposition, distribution, extraction, and retrieval of nuclear magnetic resonance (NMR) data on natural products (NP…
openalex
David S. Wishart, Tanvir Sajed, Matthew Pin, Ella F Poynton 等
2024-11-22
置信度 0.72
DatabaseSpectral lineRaw dataNMR spectra databaseComputer science
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Plastic pollution is ubiquitous throughout the marine environment, yet estimates of the global abundance and weight of floating plastics have lacked data, particularly from the Southern Hemisphere and remote regions. Here we report an estimate of the total num…
openalex
Marcus Eriksen, Laurent Lebreton, Henry S. Carson, Martín Thiel 等
2014-12-10
置信度 0.72
Marine debrisPlastic pollutionMicroplasticsTransectOceanography
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Edge-cloud collaborative computing (ECCC) has emerged as a pivotal paradigm for addressing the computational demands of modern intelligent applications, integrating cloud resources with edge devices to enable efficient, low-latency processing across distribute…
openalex
Jing Liu, Yao Du, Kun Yang, Jiaqi Wu 等
2026-01-01
置信度 0.72
Computer scienceBenchmarkingData scienceCloud computingSoftware deployment
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Geochemical and biological processes that operate in the soil matrix and on the soil surface are important to the degradation of biosolids in soil. Due to the large surface area of soils it is assumed that the microbial ecology is associated with mineral soil …
openalex
Dongqi Wen, Wenjuan Zhai, Demetrios J. Moschandreas, Guanglong Tian 等
2015-12-25
置信度 0.72
BiosolidsSoil waterEnvironmental scienceSoil scienceDegradation (telecommunications)
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The adverse biological effect of nanoparticles is an unavoidable scientific problem because of their small size and high surface activity. In this review, we focus on nano-hydroxyapatite and TiO₂ nanoparticles (NPs) to clarify the potential systemic toxicologi…
openalex
Jiangxue Wang, Liting Wang, Yubo Fan
2016-05-24
置信度 0.72
NanoparticleAdverse effectDentistryChemistryMedicine
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Plant synaptotagmins (SYTs) are resident proteins of the endoplasmic reticulum (ER). They are characterized by an N-terminal transmembrane region and C2 domains at the C-terminus, which tether the ER to the plasma membrane (PM). In addition to their tethering …
openalex
Francisco Benítez‐Fuente, Miguel A. Botella
2023-06-20
置信度 0.72
Endoplasmic reticulumArabidopsisCell biologyTetheringTransmembrane domain
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ANCA-associated vasculitis (AAV) is comprised of three specific conditions: granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA). Since the publication of the last British Society for R…
openalex
Kathryn Biddle, Judith Jade, Harold Wilson-Morkeh, Madura Adikari 等
2025-06-02
置信度 0.72
RheumatologyMedicineInternal medicineANCA-Associated VasculitisVasculitis
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Abstract Magnetic fluids are excellent candidates for several important research fields including energy harvesting, biomedical applications, soft robotics, and exploration. However, notwithstanding relevant advancements such as shape reconfigurability, that h…
openalex
Marco Crepaldi, Charanraj Mohan, Erik Garofalo, Andrew Adamatzky 等
2023-03-15
置信度 0.72
Materials scienceFerrofluidNanotechnologyEngineering physicsMagnetic field
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The rapid advancement of artificial intelligent and information technology has led to a critical need for extremely low power consumption and excellent efficiency. The capacity of neuromorphic computing to handle large amounts of data with low power consumptio…
openalex
Muhammad Hamza Pervez, Ehsan Elahi, Muhammad Asghar Khan, Muhammad Jawad Nasim 等
2024-10-08
置信度 0.72
Neuromorphic engineeringComputer scienceNanotechnologyComputer architectureMaterials science
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OBJECTIVE: People who eat healthier diets are less likely to develop dementia, but the biological mechanism of this protection is not well understood. We tested the hypothesis that healthy diet protects against dementia because it slows the pace of biological …
openalex
Aline Thomas, Calen P. Ryan, Avshalom Caspi, Zhonghua Liu 等
2024-02-26
置信度 0.72
Framingham Heart StudyDementiaPaceFramingham Risk ScoreMedicine
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Abstract One of the unique features associated with the Earth is that the fraction of its surface covered by land is comparable to that spanned by its oceans and other water bodies. Here, we investigate how extraterrestrial biospheres depend on the ratio of th…
openalex
Manasvi Lingam, Abraham Loeb
2019-01-01
置信度 0.72
PlanetAstrobiologyExtraterrestrial lifeAtmosphere (unit)Earth (classical element)
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A central challenge in computational modeling of biological systems is the determination of the model parameters. Typically, only a fraction of the parameters (such as kinetic rate constants) are experimentally measured, while the rest are often fitted. The fi…
openalex
Gabriele Lillacci, Mustafa Khammash
2010-03-04
置信度 0.72
IdentifiabilityEstimatorKalman filterEstimation theoryComputer science
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In biological tissue, all eigenvalues of the diffusion tensor are assumed to be positive. Calculations in diffusion tensor MRI generally do not take into account this positive definiteness property of the tensor. Here, the space of positive definite tensors is…
openalex
Philip Batchelor, Maher Moakher, David Atkinson, Fernando Calamante 等
2004-12-22
置信度 0.72
Diffusion MRITensor (intrinsic definition)Positive definitenessGeodesicMathematics
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In a recent study published in Nature Biotechnology , Mohammad Ghazi Vakili et al. applied quantum computing and generative machine learning—specifically Quantum Circuit Born Machines (QCBMs) and Long Short-Term Memory (LSTM) networks—to efficiently explore hi…
openalex
Taeho Kwon, Hak‐Jin Kim, Hakjin Kim
2025-05-13
置信度 0.72
KRASConvergence (economics)Computational biologyComputer scienceCancer research
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Optical neural networks are considered next-generation physical implementations of artificial neural networks, but their capabilities are limited by on-chip integration scale and requirement for coherent light sources. This study proposes a spectral convolutio…
openalex
Kaiyu Cui, Shijie Rao, Sheng Xu, Yidong Huang 等
2025-01-02
置信度 0.72
Computer scienceConvolutional neural networkChipArtificial neural networkScalability
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The accumulation of genome-wide molecular data has emphasized the important role of hybridization in the evolution of many organisms, which may carry introgressed genomic segments resulting from past admixture events with other taxa. Despite a number of exampl…
openalex
Claudio S. Quilodrán, Alexandros Tsoupas, Mathias Currat
2020-09-29
置信度 0.72
IntrogressionTaxonBiologyEvolutionary biologyRange (aeronautics)
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Abstract In low‐gradient, macrophyte‐rich rivers, we expect that the significant change in macrophyte biomass among seasons will strongly influence both biological activity and hydraulic conditions resulting in significant effects on nutrient dynamics. Underst…
openalex
Tenna Riis, Jennifer L. Tank, Alexander J. Reisinger, Antoine Aubenau 等
2019-10-03
置信度 0.72
MacrophyteEnvironmental scienceNutrientBiomass (ecology)Seasonality
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BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sought to model and forecast age related cha…
openalex
Bircan Erbas, Shahid Ullah, Rob J. Hyndman, Michelle Scollo 等
2012-02-21
置信度 0.72
COPDMEDLINEMedicineGerontologyEnvironmental health
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Abstract Memristors have garnered significant attention in the field of non‐volatile memory devices due to their excellent characteristics such as miniaturization, low power consumption, high performance, and non‐volatility. Particularly with the development o…
openalex
Qing Mao, Zhenqian Zhu, Jialin Meng, Tianyu Wang
2025-05-12
置信度 0.72
Neuromorphic engineeringMemristorComputer scienceComputer architectureArtificial intelligence
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The ability of biomedical imaging data to be of quantitative nature is getting increasingly important with the ongoing developments in data science. In contrast to conventional attenuation-based X-ray imaging, grating-based phase contrast computed tomography (…
openalex
Lorenz Birnbacher, Eva-Maria Braig, Daniela Pfeiffer, Franz Pfeiffer 等
2021-04-12
置信度 0.72
TomographyContrast (vision)Phase-contrast imagingX-Ray Phase-Contrast ImagingFocus (optics)
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Abstract Introduction Despite their potential benefits, it is not well understood how the application of biostimulants influences soil biological properties and their microbial communities in field conditions. In this study, we aimed to evaluate the impacts of…
openalex
Jenendra Wadduwage, Hongwei Liu, Eleonora Egidi, Brajesh K. Singh 等
2023-06-19
置信度 0.72
Soil waterAbundance (ecology)Arable landWater contentSoil respiration
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BACKGROUND: To improve the tedious task of reconstructing gene networks through testing experimentally the possible interactions between genes, it becomes a trend to adopt the automated reverse engineering procedure instead. Some evolutionary algorithms have b…
openalex
Wei‐Po Lee, Yu‐Ting Hsiao, Wei-Che Hwang
2014-01-01
置信度 0.72
Computer scienceCloud computingEvolutionary algorithmDistributed computingEvolutionary computation
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Abstract This review presents an overview of the current state‐of‐the‐art in photonics computing, which leverages photons, photons coupled with matter, and optics‐related technologies for effective and efficient computational purposes. It covers the history an…
openalex
Nikita Stroev, Natalia G. Berloff
2023-07-19
置信度 0.72
PhotonicsComputer scienceProbabilistic logicInferenceArtificial neural network
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Proteinoids, or thermal proteinoids, are produced by heating amino-acids. When placed in water, proteinoids swell into microspheres which produce neuron-like spikes of electrical potential. This study combines proteinoid microspheres with Emiliania huxleyi alg…
openalex
Panagiotis Mougkogiannis, Andrew Adamatzky
2025-07-13
置信度 0.72
AlgaeNanotechnologyBiological systemNeuromorphic engineeringMaterials science
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openalex
Rashmi Jain, E. Kransdorf, Jennifer Cowger, Valluvan Jeevanandam 等
2024-11-20
置信度 0.72
MedicineHeart transplantationTransplantationHeart failureSelection (genetic algorithm)
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Approximate Bayesian computation (ABC) constitutes a class of computational methods rooted in Bayesian statistics. In all model-based statistical inference, the likelihood function is of central importance, since it expresses the probability of the observed da…
openalex
Mikael Sunnåker, Alberto Giovanni Busetto, Elina Numminen, Jukka Corander 等
2013-01-10
置信度 0.72
Approximate Bayesian computationLikelihood functionStatistical inferenceInferenceComputer science
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Importance: It remains unclear whether obesity accelerates biological aging, potentially leading to early-onset chronic diseases. Objective: To investigate the association between long-term obesity and the expression of biochemical aging markers in younger adu…
openalex
Paulina Correa‐Burrows, Raquel Burrows, Cecilia Albala, Carlos Sepúlveda 等
2025-07-11
置信度 0.72
ObesityMedicineBody mass indexLife course approachCohort
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Eumelanin (EM) and pheomelanin (PM) are ubiquitous in mammalian skin and hair--protecting against harmful radiation from the sun. Their primary roles are to absorb solar radiation and efficiently dissipate the excess excited state energy in the form of heat wi…
openalex
Barbara Marchetti, Tolga N. V. Karsili
2015-12-24
置信度 0.72
PhotoprotectionSunscreening AgentsNatural (archaeology)ChemistryNanotechnology
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Biological subphenotypes have been identified in acute respiratory distress syndrome (ARDS) based on two parsimonious models: the "uninflamed" and "reactive" subphenotype (cluster-model) and "hypo-inflammatory" and "hyper-inflammatory" (latent class analysis (…
openalex
Nanon F. L. Heijnen, Laura A. Hagens, Marry R. Smit, Marcus J. Schultz 等
2021-02-01
置信度 0.72
ARDSImmunologyTumor necrosis factor alphaInflammationMicrobiome
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Fog computing is an emerging computing paradigm that has come into consideration for the deployment of Internet of Things (IoT) applications amongst researchers and technology industries over the last few years. Fog is highly distributed and consists of a wide…
openalex
Abdullah Al-Noman Patwary, Ranesh Kumar Naha, Saurabh Garg, Sudheer Kumar Battula 等
2021-05-14
置信度 0.72
Computer securityFog computingComputer scienceSoftware deploymentAccess control
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This is the English version of Japanese guidance for use of biologics for psoriasis (the 2022 version). As the first biologics for psoriasis in Japan, infliximab and adalimumab, anti-tumor necrosis factor-α antibodies, became available in the field of dermatol…
openalex
Hidehisa Saeki, Tomotaka Mabuchi, Akihiko Asahina, Masatoshi Abe 等
2022-12-29
置信度 0.72
PsoriasisDermatologyMedicine
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Abstract The previous chapter introduced the enumerative DNA computation model for solving NP-complete problems, but with the increase of problem size, the amount of DNA molecules in the generated initial solution space will inevitably show an “exponential exp…
crossref
Jin Xu
2025-04-10T11:10:29Z
置信度 0.70
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crossref
Kara Peterson, Deborah Sulsky, Adrian Turner, Svetoslav Nikolov 等
2026-02-18T20:43:25Z
置信度 0.70
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In silico trials for drug safety assessment require a large number of high-fidelity 3D cardiac electrophysiological simulations to predict drug-induced QT interval prolongation, making the process computationally expensive and time-consuming. These simulations…
preprints
2024
置信度 0.74
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Amyloid self-assembled from amyloid peptides βΑ40 or βΑ42 is notorious for its neurotoxic effects in plaque and neurofibrillary tangle formations leading to neuron dysfunction and diseases of cognitive decline (e.g. Alzheimer’s, Parkinson’s and Huntington'…
preprints
2024
置信度 0.74
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Neocortical synapses are highly dynamic during brain development, undergoing formation, elimination, and maturation before acquiring properties that support adult cognition. Individual neocortical regions develop at different ages and individual layers within …
preprints
2026
置信度 0.74
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Long-read sequencing enables the incorporation of isoform-level expression into single-cell transcriptomic studies, offering detail beyond those accessible with short-read methods. Although insightful, these approaches have typically been costly and yielded li…
preprints
2025
置信度 0.74
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Pest damage exhibits considerable spatial heterogeneity among individual plants in the field. While such spatial heterogeneity has often been treated as a nuisance in crop breeding trials, underlying biotic factors and loci remain poorly understood. To quantif…
preprints
2025
置信度 0.74
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Simultaneous Localization and Mapping (SLAM) is a crucial function for most autonomous systems, allowing them to both navigate through and create maps of unfamiliar surroundings. Traditional Visual SLAM, also commonly known as VSLAM, relies on frame-based came…
preprints
2024
置信度 0.74