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• Mapping the magnetoreceptive brain: A 3D digital atlas of the migratory bird Eurasian blackcap ( <i>Sylvia atricapilla</i> )
  Birds undisputedly range amongst nature’s foremost navigators. To successfully navigate between breeding and wintering quarters, they, in addition to other natural orientation cues, rely on their ability to sense the Earth’s magnetic field. For this reason, mi…
  preprints 2025 置信度 0.74
• Examining Neurodiversity and Inclusion in Neuroscience Research Networks: A Case Study of the AIMS-2-TRIALS Autism Research Consortium.
  Due to the increased emphasis on co-produced and community led research, neurodiversity within research communities has sparked interest, particularly within the context of autism research. This study investigates the presence of neurodivergent researchers wit…
  preprints 2024 置信度 0.74
• Neuronal recordings in head-fixed and freely-moving mole-rats
  Mole-rats are subterranean rodents that have evolved remarkable sensory adaptations to life in underground tunnel systems, yet their neural mechanisms remain largely unexplored. Here, we present a protocol for in vivo electrophysiological recordings in awake, …
  preprints 2025 置信度 0.74
• Identifying differential interactions of traumatic experiences with genetic risk for posttraumatic stress disorder
  Abstract Background: Posttraumatic stress disorder (PTSD) occurs following traumatic experiences, but not everyone who experiences trauma develops PTSD. Genetic factors play an important role in shaping how individuals respond to trauma, a form of gene-environ…
  preprints 2026 置信度 0.74
• Network-based disease fingerprinting with neuroinflammation PET imaging
  Abstract Neuroinflammation is a hallmark of numerous neurodegenerative, psychiatric, and chronic pain disorders and can be assessed in vivo with 18 kDa translocator protein (TSPO) positron emission tomography (PET). However, conventional quantification methods…
  preprints 2025 置信度 0.74
• Predicting continuous amyloid PET levels with CSF and plasma brain-derived p-tau217.
  Staging amyloid beta (A&#x3b2;) burden along a continuous spectrum provides clinically relevant information. Conventional phosphorylated tau (p-tau)217 reliably identifies amyloid positron emission tomography (PET) positivity, but its ability to capture the fu…
  pubmed Trudel L, Therriault J, Macedo AC, Aumont E 等 2026 Aug 置信度 0.82
• Head and Neck Verrucous Carcinoma: A European Multicenter Retrospective Study.
  We characterized oncological outcomes of head and neck verrucous carcinomas (HNVC) and explored treatment-associated outcomes.
  pubmed Schrooyen AS, Vaira LA, Boscolo-Rizzo P, Brunet A 等 2026 Aug 5 置信度 0.82
• CXCL10 contributes to female-specific pathological progression in tauopathy model mice.
  Neuroinflammation plays a central role in the progression of tauopathy via the glial activation and T cell accumulation in the brain parenchyma. However, the key molecular mediators that link these processes to tau pathology remain poorly understood.Here, we i…
  pubmed Uenishi R, Kawata R, Manabe T, Matsuba Y 等 2026 Aug 5 置信度 0.82
• Triaging general practitioner referrals for specialist review to eConsultant - a pilot study.
  eConsultant is an asynchronous, digital, clinician-to-clinician advice service, giving general practitioners rapid remote access to specialist support for patient care. This study aimed to assess the feasibility, acceptability, and appropriateness of a model t…
  pubmed Job J, Nicholson C, Strauss R, Tsai MC 等 2026 Aug 17 置信度 0.82
• Normal limits for the right ventricle-pulmonary circulation exercise echocardiography: a meta-analysis.
  Normal limits for exercise Doppler echocardiography (ex-TTE) measurements of the right ventricle (RV), pulmonary artery (PA) and left atrial (LA) unit remain inadequately defined. This meta-analysis aims to establish normal limits for measurements of the RV-PA…
  pubmed Ferrara F, Capone V, Franzese M, Carbone A 等 2026 Jul 置信度 0.82
• Implementation of an Intern Night Float Rotation in a Neurosurgery Residency Program: Perspectives on Patient Safety and Educational Value.
  Traditional 24-hour call systems in surgical training often result in educational fragmentation, with post-call days causing interruptions in operative experience, particularly for senior residents. By contrast, night float systems may help reduce interruption…
  pubmed Ng GY, Mazurek MH, Cruise K, Smith WJ 等 2026 Aug 5 置信度 0.82
• Non-contrast computed tomography at the end of the acute care phase as an additional prognostic tool after aneurysmal subarachnoid hemorrhage.
  Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition with high morbidity and mortality. Long-term outcomes remain difficult to predict. Computed tomography (CT) is central to diagnosis and early risk stratification, yet the prognostic valu…
  pubmed Ludovichetti R, Barbagallo M, De Trizio I, Maralushaj M 等 2026 Aug 4 置信度 0.82
• Microglial 5-LOX-activating protein antagonism alleviates leukotriene-driven neuroinflammation.
  In multiple sclerosis (MS), the chronic, unresolved nature of neuroinflammation within the central nervous system (CNS) remains a major obstacle for effective therapeutic intervention. This challenge arises primarily due to an incomplete understanding of the d…
  pubmed Konings J, Mingneau F, Chornyi S, Hansen CE 等 2026 Aug 4 置信度 0.82
• Temporal patterns of alcohol use in alcohol use disorder: a 12-month ecological momentary assessment.
  Alcohol consumption (AC) is a major contributor to preventable morbidity and mortality. Fine-grained, near real-time data may capture short-term fluctuations in alcohol use, yet evidence on long-term temporal drinking patterns remains limited. Using smartphone…
  pubmed Bahr NS, Heinz A, Rapp MA, Reichert D 等 2026 Aug 4 置信度 0.82
• Improved peripheral airway reactance is associated with clinical remission following biologic therapy in severe asthma.
  Small airways dysfunction (SAD) is increasingly recognised as a treatable trait in severe asthma and may influence the likelihood of achieving clinical remission.
  pubmed Lim JV, Lipworth B, Menzella F, Usmani O 等 2026 Aug 3 置信度 0.82
• A Faster Way to Diagnose Multiple Sclerosis: The Central Vein Sign in Routine Clinical Practice.
  The central vein sign (CVS) was included in 2024 McDonald criteria but remains underutilized in clinical practice. Implementation of CVS may reduce the requirement for lumbar punctures (LPs). At Nottingham, UK academic multiple sclerosis (MS) center, we implem…
  pubmed Gilmartin CGS, Paskin T, Clarke MA, De Dios Peréz B 等 2026 Oct 置信度 0.82
• Learning to Be Kind to Me: A Compassion-Focused Group for Adolescents With Anorexia Nervosa.
  Anorexia nervosa (AN) is often characterised by high levels of shame and self-criticism. Compassion-Focused Therapy (CFT) is a transdiagnostic intervention targeting these emotional vulnerabilities, yet its application in adolescent eating disorder services re…
  pubmed Drew T, Fox P, Waton C, Hyatt I 等 2026 Aug 3 置信度 0.82
• Serum Glial Fibrillary Acidic Protein Dynamics, Disease Progression, and Therapy Response in Multiple Sclerosis.
  Capturing individual multiple sclerosis (MS) progression is difficult; few studies have evaluated glial fibrillary acidic protein (GFAP) in large longitudinal cohorts with independent validation.
  pubmed Einsiedler M, Sandgren S, Schaedelin S, Ning K 等 2026 Aug 3 置信度 0.82
• Systematic Screening of Communication Outcomes at Age 5 in Children Treated for Nonsyndromic Craniosynostosis.
  Previous research on communicative outcomes in children treated for nonsyndromic craniosynostosis (NSC) has yielded inconsistent findings, with reported prevalence rates of communicative difficulties varying widely. These discrepancies are attributable to smal…
  pubmed Weinfeld J, Havstam C, Kljajić M, Psychol C 等 2026 Sep-Oct 置信度 0.82
• A Quality Improvement Study on Patient-Perceived Participation in Care Decisions at a Comprehensive Stroke Center Using a Standardized Patient Information Tool.
  Acute stroke care involves complex decisions that may limit patient understanding in care decisions. Review of National Research Corporation (NRC) patient experience survey data at a Comprehensive Stroke Center identified that patient-perceived participation i…
  pubmed Inamullah O, Hendrix L, Jones Z 2026 置信度 0.82
• Applicability and reliability of the IDDSI functional diet scale (IDDSI-FDS) in clinical reports of patients with oropharyngeal dysphagia.
  The International Dysphagia Diet Standardization Initiative Functional Diet Scale (IDDSI-FDS) was developed to quantify functional oral intake within the IDDSI framework. Although promising, evidence supporting its use in routine clinical documentation remains…
  pubmed Silva-Carvalho I, Martins A, Silva M, Lino J 等 2026 Aug 3 置信度 0.82
• Endoscopic and combined approaches in the surgical management of frontal and ethmoidal sinus osteomas: a novel decision-making flowchart.
  Paranasal sinus osteomas are benign but potentially symptomatic lesions whose management remains heterogeneous despite recent advances. Choosing between a purely endoscopic or a combined approach can be challenging, particularly for larger lesions. This study …
  pubmed Romano A, Troise S, Esposito M, Spinelli R 等 2026 Aug 3 置信度 0.82
• Caregiver Burden and Well-being of Caregivers to Hospitalized Filipino Children with Neurological Conditions: A Cross-sectional Study.
  Taking care of pediatric patients with neurological conditions in prolonged hospital stays can affect caregivers' health due to the demands of caregiving beyond daily parenting.
  pubmed Ceblano LC, Sanchez-Gan BC, Orduña PC 2026 置信度 0.82
• Management of major organ involvement in Behçet syndrome: a systematic literature review informing the 2025 update of the EULAR recommendations.
  The objective of this study was to evaluate and update the evidence on pharmacologic and interventional treatments for major organ involvement in Beh&#xe7;et syndrome (BS), in order to inform the 2025 update of the European Alliance of Associations for Rheumat…
  pubmed Ozguler Y, Esatoglu SN, Tomasson G, Falzon L 等 2026 Jun 置信度 0.82
• Diffuse cauda equina nerve root enlargement: diagnostic challenges, clinicopathological spectrum, and the role of surgical biopsy.
  Diffuse enlargement of the cauda equina nerve roots is an uncommon radiological finding that may result from various causes, including neoplastic, inflammatory, and immune-mediated conditions. Because these causes have overlapping imaging features, it remains …
  pubmed Lu C, Wang X, Yin M, Si H 2026 置信度 0.82
• Towards sustainable healthcare in otorhinolaryngology: assessing knowledge, engagement, and opportunities for change.
  Healthcare systems contribute up to 5% of global greenhouse gas emissions, with impacts varying across medical specialties. Otorhinolaryngology (ORL) and hearing care must address their specific environmental footprint to meet emerging sustainability goals. Th…
  pubmed Anderson I, Acharya A, Baumann U, Brown KD 等 2026 置信度 0.82
• Fever Burden and Neurological Outcome in Traumatic Spinal Cord Injury.
  Fever is a frequent complication after traumatic spinal cord injury (TSCI) and may exacerbate secondary neurological damage through increased metabolic demand, inflammation, and impaired perfusion. Despite its potential impact, the role of fever in TSCI remain…
  pubmed Rochat T, Legouis D, Pia S, Hervé Q 2026 Jan-Dec 置信度 0.82
• Genetic Counselor Utilization Across Non-Genetics Departments for Neurodevelopmental Disorders.
  Most United States children with neurodevelopmental disorders have not received genetic testing aligned with current guidelines. Integration of genetic counselors into non-genetics departments is a potential strategy to improve uptake, but prevalence and detai…
  pubmed Cole JJ, Cohen JS, Sahin M, Srivastava S 等 2026 Jul 21 置信度 0.82
• Dysregulated Pain-Autonomic Responses in Patients With Nonspecific Chronic Low Back Pain.
  Neurophysiological assessments might advance the understanding of nonspecific chronic low back pain (nsCLBP) by quantifying altered pain processing and associated autonomic responses. Contact heat-evoked potentials (CHEPs) and sympathetic skin responses (SSRs)…
  pubmed Chozas Barrientos B, De Schoenmacker I, Scheuren PS, Sirucek L 等 2026 置信度 0.82
• Artificial Intelligence in Renal Transplantation: Current Innovations and Future Horizons.
  This study critically examined the evolving role of artificial intelligence (AI ) in kidney transplantation, aiming to bridge the gap between theoretical promise and clinical implementation. The study evaluated AI -driven innovations across the transplant cont…
  pubmed Okhovvat M, Amirkhanlou S, Simforoosh N, Poor-Reza Gholi F 2026 Jul 置信度 0.82
• Cerebrospinal fluid haemoglobin as a monitoring biomarker for secondary brain injury after aneurysmal subarachnoid haemorrhage: prospective international multicentre validation study (HeMoVal).
  To validate whether cerebrospinal fluid oxyhaemoglobin (CSF-Hb), measured from external ventricular or lumbar drains, is associated with secondary brain injury (SAH-SBI) after aneurysmal subarachnoid haemorrhage (aSAH) and to assess its value as a real-time mo…
  pubmed Akeret K, Buzzi RM, Gentinetta T, Saxenhofer M 等 2026 Jul 31 置信度 0.82
• Standardized evaluation of automatic methods for perivascular spaces segmentation in MRI - MICCAI 2024 challenge results.
  Perivascular spaces (PVS), when abnormally enlarged and visible in magnetic resonance imaging (MRI) structural sequences, are important imaging markers of cerebral small vessel disease and potential indicators of neurodegenerative conditions. Despite their cli…
  pubmed Wu Y, Zhang Y, Dong Z, Ji F 等 2026 Jul 20 置信度 0.82
• A Ubiquitous Blood Flow Biomarker to Calculate Hypoxic-Ischemic Depolarization Latency in a Mouse Model of Focal Ischemic Stroke: Insight Into Metabolic and Electrophysiological Resilience.
  Focal cerebral ischemia, when sufficiently severe and prolonged, culminates in a near-complete loss of neuronal membrane potential in the ischemic core, known as hypoxic-ischemic depolarization (HID). The vasoconstrictive effect of HID causes an abrupt reducti…
  pubmed Noya A, Morais A, Li M, Lee JH 等 2026 Jul 31 置信度 0.82
• Photoreceptors integrity as surrogate of retinal sensitivity in chronic central serous chorioretinopathy: a multimodal imaging study.
  To assess the correlation between photoreceptor mosaic integrity in chronic central serous chorioretinopathy (cCSCR) and multiple morpho-functional parameters, including photoreceptor density (PD), normalized reflectivity of photoreceptor layers (NR-PRL), norm…
  pubmed Lupidi M, Muzi A, Gregori G, Fruttini D 等 2026 Jul 31 置信度 0.82
• Polypharmacy, multimorbidity, and socioeconomic inequalities in a Spanish region: a population-based cross-sectional study.
  Polypharmacy is closely linked to multimorbidity in older adults, but its distribution may also reflect social inequalities in health. We aimed to describe pharmacological burden and multimorbidity among individuals with polypharmacy in La Rioja, Spain, and to…
  pubmed Aparicio-Rodriguez G, Juárez-Vela R, Larráyoz IM, Santos-Sánchez JÁ 等 2026 置信度 0.82
• Light-activated tetanus neurotoxin for conditional proteolysis and inducible synaptic inhibition in vivo.
  The light chain of tetanus neurotoxin (TeNT) is a metalloprotease that potently inhibits synaptic transmission by cleaving the endogenous vesicle fusion protein VAMP2, but its constitutive activity prevents spatiotemporal precision. To address this, we enginee…
  pubmed Roh H, Kim D, Kim B, Jeon Y 等 2026 Aug 置信度 0.82
• Hippocampal theta distinguishes between memory-guided and exploratory saccades in humans.
  Memory shapes how we explore the visual world, but the neural mechanisms linking mnemonic processes to eye movements during naturalistic viewing are not well understood. Theta-band oscillatory activity in the hippocampus is time-locked with eye movements in pr…
  pubmed Castelblanco Riveros CA, Angeli PA, van der Meer MAA, Bujarski KA 等 2026 Jul 30 置信度 0.82
• Long-term Electrode Impedance Performance in Ambulatory Video-EEG: A Retrospective Comparison of Two Adhesives.
  To compare collodion and a water-soluble adhesive for maintaining electrode impedance during prolonged ambulatory video-EEG.
  pubmed Nurse E, Marlow K, Hennessy PJ, Knight-Sadler R 等 2026 Jul 30 置信度 0.82
• Alzheimer disease in the computational era: from a deterministic disease to a multifaceted disorder.
  The definition of Alzheimer disease (AD) keeps changing over the years, which is critical for studying it, understanding it, and developing treatments. Here we first review the different definitions proposed for AD from its original characterization by Kraepel…
  pubmed Benbaji M, Raveh B, Bassal L, Elias U 等 2026 Jul 30 置信度 0.82
• Antidepressant-like effects of valproic acid in rodents go back to the 1980s: a comment to enrich the reviewed evidence by Goudarzi et al. (2026) "Valproic acid effects on stress-induced depression-like behavior in rodent models: a systematic review and meta-analysis".
  In a recent review and meta-analysis, Goudarzi et al. (Stress, 2026 Dec 31; 29(1):2641561) show that valproic acid (VPA) exhibits antidepressant (AD)-like effects in several procedures involving the induction of depression-like symptoms by prior sub-chronic or…
  pubmed Fernández-Teruel A 2026 Dec 31 置信度 0.82
• FREQ-NESS Reveals Age-Related Differences in Frequency-Resolved Brain Networks During Auditory Recognition and Resting State.
  Understanding how brain networks operate across different frequencies during cognitive tasks, and how these dynamics change with age, remains a central challenge in cognitive neuroscience. While previous studies have focused on resting-state activity and passi…
  pubmed Malvaso C, Fernández-Rubio G, Rosso M, Serra E 等 2026 Aug 置信度 0.82
• Clinical Outcome of Epilepsy Surgery of The Temporal Lobe in Paediatric Group: A Retrospective Cohort Study.
  This study was to identify seizure outcome following epilepsy surgery in paediatric group using Engel classification. We also identified histological and radiological findings of the study population.
  pubmed Mohd Mispan MK, Alias A, Mohamed AR, Kassim F 等 2025 Dec 置信度 0.82
• Competing with greater impairment: age distribution and competitive outcomes in Paralympic athletes with high support needs.
  This study examined the age distribution of Paralympic athletes with high support needs at the Paris 2024 Paralympic Games, analyzing differences according to sex, competitive achievement, and discipline. A total of 1,263 athletes from eight individual sports …
  pubmed Kons RL, Santos LGT, Apollaro G, Magno E Silva MP 等 2026 置信度 0.82
• Physical activity and exercise in primary open-angle glaucoma: a scoping review.
  Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide. Although intraocular pressure (IOP) reduction remains the cornerstone of management, increasing attention has focused on physical activity (PA) and structured exercise a…
  pubmed Schuhmann V, Küttel J, Van Eijgen J, Gugleta K 等 2026 置信度 0.82
• Parent-delivered Hand-arm Bimanual Intensive Training Including Lower Extremity for young children with bilateral cerebral palsy in Vietnam: protocol for a randomised controlled trial.
  Cerebral palsy (CP) is a leading cause of long-term disability for children in Vietnam and across the world, affecting both gross and fine motor skills as well as daily independence. Intensive therapy has been shown to significantly improve motor outcomes. Mor…
  pubmed Nguyen MND, Le HTN, Nguyen TV, Do TP 等 2026 Jul 29 置信度 0.82
• Global Research Trends of Protein Post-translational Modifications in Alzheimer's Disease: A Bibliometric Analysis.
  In recent years, a considerable body of research has increasingly underscored the critical roles that protein Post-Translational Modifications (PTMs) play in the pathogenesis of Alzheimer's Disease (AD). However, a comprehensive bibliometric analysis of this f…
  pubmed Wei Z, Qian H, Dai C, Wu J 等 2026 Jul 26 置信度 0.82
• Testing an integrated model of population mental health: study protocol for the epidemiological, two-arm Mannheim incidence and inception cohort study (MAKO).
  Monitoring of population mental health is now considered to play a vital role in health, risk factor and demographic surveillance systems across the globe. Adopting a public mental health perspective on monitoring and surveillance requires us to consider the e…
  pubmed Reininghaus U, Wierzba E, Schick A, Hartmann JA 等 2026 Jul 28 置信度 0.82
• A systematic review of highly purified cannabidiol in developmental and epileptic encephalopathies and complex treatment-resistant epilepsies: Nonseizure outcomes.
  A plant-derived, highly purified cannabidiol (CBD) oral solution (Epidiolex&#xae; [US]/Epidyolex&#xae; [EU]) is approved for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC). Imp…
  pubmed Samanta D, Moore-Ramdin L, Navetta M, Coppola A 2026 Jul 14 置信度 0.82
• Development and Evaluation of Individualized Music Therapy for Common Mental Disorders: Protocol for a Multistage Study.
  Pharmacotherapy for common mental disorders is frequently limited by adverse events and suboptimal adherence. While music therapy offers a promising nonpharmacological alternative, its clinical utility is currently constrained by limited accessibility, inconsi…
  pubmed Xiao C, Wei J, Li T, Cao J 等 2026 Jul 28 置信度 0.82
• The COMPASS-MS Study on Implementing Digital Assessment and Treatment for Psychological Distress in Patients With Multiple Sclerosis: Protocol for a Real-World Longitudinal Study.
  Comorbid anxiety and depression in patients with multiple sclerosis (MS) are common, conferring a greater risk of poorer outcomes and increased health care costs. Few MS services include scalable treatment pathways for psychological distress.
  pubmed Jenkinson E, Moss-Morris R, Seaton N, Silber E 等 2026 Jul 28 置信度 0.82
• Robotic-assisted cholecystectomy in children is associated with faster gastrointestinal recovery: a comparative study.
  The role of robotic-assisted cholecystectomy in paediatric patients remains incompletely defined, particularly regarding postoperative recovery and gastrointestinal function. This study aimed to compare perioperative outcomes and early recovery between robotic…
  pubmed Di Mitri M, Cantagalli MM, Morabito A, Brucculeri A 等 2026 置信度 0.82
• Reduced Effect of APOE4 on White Matter Microstructure in an American Indian Community.
  Apolipoprotein E4 ( APOE4 ) is central to Alzheimer disease (AD) personalized medicine, yet its link to AD is highly ancestry-dependent. Emerging evidence suggests an attenuated risk of APOE4 on brain health in American Indian (AI) participants. This study exa…
  pubmed Labounek R, Matheson MJ, Strong CA, Petersen A 等 2026 Aug 置信度 0.82
• Plasma Amyloid-β 1-40 and Postoperative Delirium After Cardiac Surgery.
  Postoperative delirium (POD) is a frequent and severe complication after cardiac surgery that is associated with increased risk of dementia and adverse outcomes. Early identification of high-risk patients remains challenging.
  pubmed von Arnim CAF, Sadlonova M, Derad C, Hohberg M 等 2026 Jul 1 置信度 0.82
• Primary care-based interventions for post-stroke follow-up for long-term care: a systematic review.
  Life after stroke is managed by primary care to prevent recurrent stroke and ensure that stroke survivors live well within the community. Unfortunately, stroke survivors do not always receive timely follow-up from clinical services, which leads to unaddressed …
  pubmed Ravenhall H, Sabatini S, De Ivey R, Errington L 等 2026 Jun 11 置信度 0.82
• Retraction of the landmark glyphosate safety publication by Williams, Kroes and Munro (2000) should be reversed.
  The decision by the co-Editor-in-Chief of Regulatory Toxicology and Pharmacology, Prof. Martin van den Berg, to retract the 2000 review article by Williams, Kroes, and Munro has elicited widespread criticism within the scientific community. Issued in late 2025…
  pubmed Borgert CJ, Abdollahi M, Ansell JM, Aschner M 等 2026 置信度 0.82
• Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world.
  In response to a Cochrane review (published in April 2026) on the clinical trials of monoclonal antibodies targeting beta amyloid, this perspective outlines a number of critiques. The scientists, methodologists, subject-matter experts, and clinicians on this p…
  pubmed Snyder HM, Tampi MP, Aisen PS, Allegri R 等 2026 Jul 置信度 0.82
• A High Proportion of Encephalitozoon cuniculi Antibody-Positive Domestic Rabbits Identified in Northern Portugal: Implications for Zoonotic Risk.
  Encephalitozoon cuniculi is a globally distributed microsporidian of veterinary and public health relevance, particularly due to its zoonotic potential and high prevalence in domestic rabbits ( Oryctolagus cuniculus ). This study aimed to estimate the presence…
  pubmed Rocha F, Gibson MS, Anastácio S, Vilhena H 等 2026 Jul 10 置信度 0.82
• Functional and Structural Outcomes of Photodynamic Therapy (PDT) With or Without Eplerenone for Central Serous Chorioretinopathy.
  Background/Objectives : To evaluate whether the combination of oral eplerenone and half-dose full-fluence photodynamic therapy (HD-FF PDT) provides greater efficacy than HD-FF PDT alone in persistent central serous chorioretinopathy (CSCR). Methods : This mono…
  pubmed Gregori G, Centini C, Mangoni L, Muzi A 等 2026 Jul 21 置信度 0.82
• Anterior Versus Posterior Surgical Approaches in Degenerative Cervical Myelopathy: A Single-Center Retrospective Comparative Study of 102 Patients.
  Background/Objectives: Degenerative cervical myelopathy (DCM) is the leading cause of non-traumatic spinal cord dysfunction in adults. Both anterior and posterior surgical approaches are widely used for its treatment, yet their comparative impact on clinical o…
  pubmed Anselmi L, Da Broi M, Nouri A, Bouhalassa N 等 2026 Jul 13 置信度 0.82
• From Acute Symptomatic Seizures to Post-Stroke Epilepsy: A Narrative Review of Diagnosis and Management.
  Stroke is a major cause of acquired epilepsy in adults, particularly in older individuals. However, seizures after stroke should not be regarded as a single clinical entity. Acute symptomatic seizures (ASyS) occur within the first seven days after stroke and a…
  pubmed Frezatti T, Roever L, Pontes-Neto O 2026 Jul 8 置信度 0.82
• Comparative Short-Term Clinical Outcomes of Hybrid Hyaluronic Acid and Platelet-Rich Plasma Injections in Knee Degenerative Conditions: An Exploratory Real-World Retrospective Study.
  Background and Objectives : Knee osteoarthritis (KOA) and other degenerative chondropathies are major causes of pain and disability. When core conservative treatments are insufficient, intra-articular hyaluronic acid (HA) and platelet-rich plasma (PRP) are com…
  pubmed Librale F, Monaco A, Di Lorenzo A, Ranieri M 等 2026 Jun 26 置信度 0.82
• Motor Training Integrating Cognitive-Behavioral Strategies and Narrative Grammar in Children with Autism Using the Global Integration Method (MIG): A Randomized Clinical Trial.
  Introduction: A high prevalence of motor deficits has been documented in individuals with Autism Spectrum Disorder (ASD); these deficits negatively impact participation and functional performance. Conventional interventions, which are often fragmented, may lim…
  pubmed Flores Cruz TK, Netto RDCP, Fernandes EBC, Nascimento AAAC 等 2026 Jul 21 置信度 0.82
• Mandibular Advancement Device Therapy in 182 DISE-Selected Adults with Moderate-to-Severe Obstructive Sleep Apnea: A Multicenter Real-World Study.
  Background/Objectives : The study evaluates the effectiveness of mandibular advancement device (MAD) treatment in drug-induced sleep endoscopy (DISE) preselected adults with moderate-to-severe obstructive sleep apnea (OSA). Methods : It is a retrospective obse…
  pubmed Braem MJ, Lins M, Van Den Bergh A, Verhelst F 等 2026 Jul 22 置信度 0.82
• Impaired Myogenic Differentiation Is a Shared Feature Across Genetic Myopathies.
  There is a shared hallmark of defective differentiation across genetic myopathies, a process that has been extensively described in Duchenne muscular dystrophy and also observed in Emery-Dreifuss muscular dystrophy. In this article, we broaden the discussion o…
  pubmed Soule TGB, Slavin MB, Pontifex CS, Dabaja MZ 等 2026 Jul 16 置信度 0.82
• The Hidden Burden of Depression in STEMI: Effects on Early Complications and 12-Month MACCE.
  Background/Objectives : Depression is a frequent but underrecognized comorbidity in ST-segment elevation myocardial infarction (STEMI) and is associated with adverse cardiovascular outcomes. The interplay between pre-existing depression, systemic inflammation,…
  pubmed Herlaș-Pop A, Radu AF, Radu A, Bungau GS 等 2026 Jul 13 置信度 0.82
• Affective Processing in Depression Risk: Insights From Event-Related Potentials.
  A mechanism that might be implicated in the etiopathogenesis of depression is a blunted activation of the Positive and Negative Valence Systems, leading to a reduced elaboration of emotional stimuli. Yet, relatively little attention has been devoted to disenta…
  pubmed Dell'Acqua C, Imperatori C, Mologni V, Ardito RB 等 2026 Jul 置信度 0.82
• Incidence, Predictors, and Outcomes of Symptomatic Intracranial Hemorrhage after Tenecteplase in Acute Ischemic Stroke.
  Symptomatic intracranial hemorrhage (SICH) after thrombolysis is a major safety concern in the management of acute ischemic stroke (AIS). This study evaluates the predictors and outcomes of SICH among AIS patients receiving tenecteplase.
  pubmed Dutta A, Chakraborty U, Gupta S, Banerjee S 等 2026 Jul 1 置信度 0.82
• Masseter Muscle in Somatosensory Tinnitus and Potential Therapeutic Role for Botulinum Toxin Type A: A Scoping Review.
  Background : Increasing evidence supports the existence of a somatosensory subtype of tinnitus, in which craniocervical-craniomandibular structures can modulate tinnitus perception also through central auditory pathways. Despite growing mechanistic evidence, n…
  pubmed Gardellin J, D'Angelo M, Spadotto L, Checchin G 等 2026 Jul 17 置信度 0.82
• Neuromodulation in Neuro-Oncology: A Scoping Review.
  Background: Neuromodulation is a rapidly developing field with growing interest in its application in neuro-oncology, particularly since the publication of the EF-14 trial which demonstrated a survival benefit conferred by tumour treating fields (TTF) in patie…
  pubmed Kamaludin AI, Kumaria A, Ashkan K 2026 Jun 28 置信度 0.82
• 1-D Collocated Dual-Gradient Sensory Fibers for Comprehensive Sensing and Decoding of Complex Human Motion and Physiology.
  Wearable interfaces that capture both weak physiological fluctuations and large body motions remain difficult to realize in a single fiber because most strain-sensing fibers are governed by one dominant electromechanical response mode. Consequently, mechanical…
  pubmed Lee Y, Jeon S, Kim M, Won J 等 2026 Jul 27 置信度 0.82
• Theoretical and practical challenges for capturing reserve and resilience in aging and Alzheimer's disease: A narrative review.
  The concepts of reserve and resilience in aging and Alzheimer's disease (AD) are widely used but their operationalization remains challenging and often lacks conceptual and methodological consistency. In this narrative review, we describe the chronological his…
  pubmed Ourry V, Wagner M, Groot C, Boyle R 等 2026 Jul 置信度 0.82
• Demographics and clinical outcomes of autistic children and adolescents receiving psychiatric in-patient care in the Thames Valley from 2019 to 2024: retrospective cohort study.
  Many autistic adolescents receive in-patient psychiatric care from services that are ill-equipped to meet neurodivergent needs. However, the outcomes for autistic adolescents accessing in-patient care remain poorly understood.
  pubmed Lloyd-White S, Borschmann R, Rorke A, Stark E 等 2026 Jul 24 置信度 0.82
• Validation of portable, semi-dry electrode-based electroencephalography device for its application in brain-computer interface solutions.
  In recent years, commercial lightweight electroencephalography (EEG) headsets are gaining popularity in neuroscience. These devices commonly utilize only a few dry electrodes in specific locations and signal quality is often inferior compared to that of their …
  pubmed Rokai J, Rácz M, Becske M, Csipor J 等 2026 Jul 24 置信度 0.82
• Defining and interpreting the clinical relevance of intervention effects for patient-reported outcomes: the smallest worthwhile effect construct.
  In clinical research, statistically significant effects do not necessarily indicate that an intervention provides benefits that are meaningful to patients. This is particularly important for patient-reported outcomes, where thresholds used to interpret clinica…
  pubmed Innocenti T, Schleimer T, de Wit M, Ferreira M 等 2026 Jul 23 置信度 0.82
• Process Evaluation of Digital Mental Health Interventions for Psychosis: Scoping Review With Framework Synthesis.
  Implementing digital mental health interventions (DMHI) for those with psychosis is a persistent challenge. A process evaluation, or studies conducted alongside trials, is one research method that may address this issue. However, a synthesis of process evaluat…
  pubmed Hampshire C, Dack C, Daryan S, Fialho C 等 2026 Jul 23 置信度 0.82
• Change in alcohol consumption among French adults participating in Dry January: A 9-month prospective cohort study.
  Temporary alcohol abstinence campaigns, such as Dry January, are increasingly promoted as population-level initiatives to encourage reductions in alcohol consumption, yet evidence on longer-term changes in alcohol consumption following participation remains li…
  pubmed Rolland B, François D, Haesebaert J, Delile JM 等 2026 Jul 23 置信度 0.82
• Association between glucagon-like peptide-1 receptor agonist use and ischemic stroke severity.
  Glucagon-like peptide-1 receptor agonists (GLP-1RAs) reduce stroke incidence, but their impact on the severity of acute ischemic stroke (AIS) when events occur remains unclear. The aim of this study is to evaluate whether pre-stroke GLP-1RA use is associated w…
  pubmed Chen H, Lakhani DA, Yaddanapudi SS, Latifikhereshky S 等 2026 Oct 15 置信度 0.82
• The effect of spiritual care training on nursing students' attitudes towards caring for the dying patient.
  Death is an inevitable reality and a significant source of stress in the nursing profession. They play a vital role in providing comprehensive care for dying patients. This study aimed to determine the effect of spiritual care education on nursing students' at…
  pubmed Jafari M, Yoosefee S, Nassehi A 2026 置信度 0.82
• Pentoxifylline targets TLR4/MyD88/NF-κB signaling to ameliorate neuroinflammation and metabolic dysfunction in a rat model of chronic hypoperfusion-induced vascular cognitive impairment.
  Vascular cognitive impairment (VCI) driven by chronic cerebral hypoperfusion lacks disease-modifying therapy. We tested whether pentoxifylline (PTX), a methylxanthine phosphodiesterase inhibitor with dual hemorheological and anti-inflammatory properties, atten…
  pubmed Wang X, Xie B, Yuan X, Rong J 等 2026 Jul 23 置信度 0.82
• EEG criticality as a prognostic tool for functional outcomes in sedated pediatric intensive care patients.
  Predicting meaningful recovery in sedated patients remains a major challenge in the pediatric intensive care unit (PICU) due to the lack of reliable, behavior-independent prognostic markers for children. Criticality of electroencephalography (EEG) signals refl…
  pubmed Newman D, Grinberg M, Jones K, Woodward K 等 2026 置信度 0.82
• Video-based musculoskeletal examination of the foot and ankle: a scoping review.
  Virtual healthcare consultations are increasingly common in health care, driven by digital health advances and the need for accessible care. Video-based consultations offer opportunities to perform musculoskeletal assessments remotely, but reliable procedures …
  pubmed Claesson A, Henriksson J, Bernhardsson S, Lange E 2026 置信度 0.82
• Age Related Competitive Performance in Wheelchair Fencing Across Sports Classes: A Retrospective Cohort Study of Paralympic Games 2000 - 2024.
  To examine age related performance in wheelchair fencing Para athletes across five Paralympic Games editions, considering sex, sport class, competitive achievement, Paralympic cycle, and weapon type.
  pubmed Kons RL, Apollaro G, Bian C, de Oliveira Gulias V 等 2026 Jul 23 置信度 0.82
• Understanding and managing agitation in neurocognitive disorders: Recent insights and global perspectives.
  Agitation is a common and distressing phenomenon across neurocognitive disorders (NCD). It is linked to decreased quality of life of the person with NCD, cognitive and functional decline, increased health-care utilization and institutionalization rates, and su…
  pubmed Gerritsen DL, Van Den Bossche M, Atri A, Chumki S 等 2026 Jul 22 置信度 0.82
• Computerized Adaptive Tests for Rapid and Accurate Assessment of Autism.
  Extant diagnostic and screening tools struggle to accommodate the diverse features of autism spectrum disorder (ASD) while balancing psychometric properties with respondent burden. Bifactor multidimensional item response theory (MIRT)-based computerized adapti…
  pubmed Tseng A, Yang A, Mandocescu L, Gibbons RD 等 2026 Jul 1 置信度 0.82
• Autism Spectrum Disorder Incidence by Age and Sex in a US Health Care System, 2016 to 2024.
  Despite the increasing prevalence of autism spectrum disorder (ASD) in the US, underlying temporal trends in newly recorded diagnoses remain poorly understood.
  pubmed Messias E, Casanova E, Huang R, Battula S 等 2026 Jul 1 置信度 0.82
• Open Science Practices in Systematic Reviews From 2014 to 2024: A Cohort Study of 300 Systematic Reviews.
  Open science practices, including the preregistration of protocols and the sharing of data and code, are increasingly promoted to enhance transparency, accessibility and the reuse of research outputs. However, systematic reviews, which are essential for inform…
  pubmed Färnqvist K, Karlsson P, Wachtmeister V, Vallance P 等 2026 Jul 置信度 0.82
• Japi 2.0, a gaming platform to stimulate cognitive and socio-emotional skills in early childhood: results of a pilot randomized controlled trial.
  Early childhood is a sensitive developmental period for the acquisition of cognitive and socio-emotional skills that are strongly associated with later mental health, academic achievement, and social functioning. Children growing up in socioeconomically disadv…
  pubmed Gaete J, Ríos N, Rojas-Barahona CA, Salgado G 等 2026 Jul 21 置信度 0.82
• Cause-specific mortality due to physical illness in severe mental disorders in Europe: a population-based multi-country cohort study.
  How specific physical illnesses differentially contribute to the persistent mortality gap in severe mental illness (including schizophrenia spectrum disorders, bipolar disorder, and major depressive disorder) remains poorly understood. Using a harmonised multi…
  pubmed Gustafsson TT, Pauly V, Hamina A, Zięba M 等 2026 Aug 置信度 0.82
• Mass balance study of [(14)C]-ABBV-552, a synaptic vesicle glycoprotein 2A positive modulator, in healthy male participants following single oral dose administration.
  Synaptic density is strongly correlated with cognitive function in many neurological disorders. All synapses contain synaptic vesicle glycoprotein 2&#xa0;A (SV2A), making it a potential therapeutic target for neurodecline. ABBV-552, a high-affinity positive SV…
  pubmed Miles N, McNamee B, Soleman SI, Zadikoff C 等 2026 Jul 21 置信度 0.82
• Depression and anxiety in patients with endogenous Cushing syndrome: a nationwide matched-cohort study using affective drug dispensations.
  Cushing syndrome (CS) is associated with depression and anxiety. This study compared treated mood and anxiety disorders between patients with CS and controls, assessing differences by etiology and remission status.
  pubmed Kaminer K, Shimon I, Rudman Y, Diker-Cohen T 等 2026 Aug 3 置信度 0.82
• Social contact recovery and depressive symptoms after the pandemic lockdowns: the lasting impact of child neglect.
  Child maltreatment is a major risk factor for depression and impairs social functioning in adulthood. The COVID-19 pandemic, through its widespread social restrictions, provided a unique opportunity to examine how adults with and without histories of child mal…
  pubmed Wallimann MS, Rosenblum A, Chokhani R, Gebus S 等 2026 Dec 置信度 0.82
• Satellite Glial Cells Synthesize and Release GABA to Activate Extrasynaptic GABA(A) Receptors That Modulate Dorsal Root Ganglia Neuron Excitability.
  Sensory neurons express extrasynaptic GABA A receptors in their soma and axon, tonically activated by ambient GABA, modulating their excitability. However, the specific glial or neuronal origin of endogenous GABA that modulates this excitability has yet to be …
  pubmed Jiménez-Barrios N, González-Ramírez R, Paz-Bermúdez FJ, Raya-Tafolla G 等 2026 Sep 置信度 0.82
• Genome-wide association analyses of borderline personality disorder identify 11 loci and highlight shared risk with mental and somatic disorders.
  Borderline personality disorder (BPD) is a severe mental health condition influenced by environmental risk factors (for example, interpersonal trauma) and genetic factors. We conducted the largest genome-wide association study (GWAS) meta-analysis of BPD so fa…
  pubmed Streit F, Awasthi S, Hall ASM, Braun A 等 2026 Aug 置信度 0.82
• Global, regional, and national burden of road injuries 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
  Road injuries are a leading cause of mortality and morbidity worldwide. Years of international efforts have aimed to strengthen policy engagement, including the 2020 UN General Assembly's proclamation of the Second Decade of Action for Road Safety (2021-30), t…
  pubmed GBD 2023 Road Injuries Collaborators 2026 Sep 置信度 0.82
• The impact of anhedonia on physical health and somatic diseases: an exploratory literature review.
  Anhedonia, or the lack of interest and pleasure, is a transdiagnostic feature of mental health disorders with emerging links to physical health. This exploratory literature review investigated evidence of anhedonia's association with physical health and somati…
  pubmed Demyttenaere K, Alassiry M, Bobrowska A, Fagiolini A 等 2026 Jul 19 置信度 0.82
• Emotion encoding and decoding from human upper-body movement: The role of acceleration, dimensionless jerk, head tilt, and limb contraction.
  What kinematic features drive emotion encoding (production or expression of emotion by an expressor) and decoding (perception, interpretation, or recognition of that emotional information by a receiver) in human full-body movement? We used upper-body sensor da…
  pubmed Rao A, Fernández A, Ullén F, Roig G 等 2026 Jul 20 置信度 0.82
• Use of blood-based neurofilament light chain as an endpoint in clinical trials of neurodegenerative conditions: a scoping review.
  Neurofilament light chain (NfL) is a structural axonal protein measurable in CSF and blood, increasingly investigated as a biomarker of neuroaxonal injury in clinical and research contexts. This review aims to explore the use of blood-based NfL as an endpoint …
  pubmed Zheng Y, Bhalala OG, Chin KS, Watson R 等 2026 Jul 20 置信度 0.82
• The role of fluid restriction in acute bacterial meningitis: A systematic review.
  Acute bacterial meningitis (ABM) is a neurological emergency that requires prompt and appropriate antibiotics and corticosteroids. Previously fluid restriction was recommended in the treatment of ABM in view of studies reporting hyponatremia which was due to e…
  pubmed Netravathi M, Dhar D, Sangeeth TA, Schiess N 等 2026 Jul 20 置信度 0.82
• Patient and representative experience after amyloid PET/CT in a real-world memory clinic: a mixed-methods observational study.
  Amyloid PET/CT is increasingly used in the diagnostic evaluation of cognitive disorders; however, its real-world impact on patient and caregiver experiences remains insufficiently characterised. This study examined how amyloid PET results influence perceived d…
  pubmed Richina G, Testart Dardel N, Salvioni P, Allali G 等 2026 Jul 20 置信度 0.82
• Blood-based multimodal biomarker models for differentiating early-onset Alzheimer's disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study.
  Plasma phosphorylated tau (p-tau) biomarkers have improved the diagnosis of Alzheimer's disease (AD), but evidence in early-onset populations remains limited. We evaluated the diagnostic performance of plasma p-tau217 and p-tau181 levels in patients with early…
  pubmed Kwon HS, Moon SY, Hwang M, Kim HJ 等 2026 Jul 20 置信度 0.82