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• Etiologic spectrum of direct oral anticoagulant breakthrough stroke in atrial fibrillation: The role of pseudo-failure and non-cardioembolic mechanisms.
  Ischemic stroke may occur despite direct oral anticoagulant (DOAC) therapy in patients with atrial fibrillation (AF), yet the underlying mechanisms remain incompletely understood. Although a growing number of studies have addressed DOAC breakthrough stroke, da…
  pubmed Hegyi L, Beke A, Nemes JN, Szabó N 等 2026 Sep 置信度 0.82
• Facilitators and barriers to adopting technology in neuropsychology: the American Academy of Clinical Neuropsychology (AACN) disruptive technology initiative survey.
  The objective of this study was to characterize contemporary technology use in U.S. clinical neuropsychology and identify perceived barriers, facilitators, benefits, competencies, and training needs associated with technology adoption.
  pubmed Wolff B, Campbell LM, Marchman T, Ball AD 等 2026 Jul 19 置信度 0.82
• Impact of Relapse Burden on Recovery and Disability Following Acute Attacks in Neuromyelitis Optica Spectrum Disorder: A 10-Year Northern Thailand Cohort.
  Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease in which disability is largely relapse-driven. The effect of relapse burden on post-relapse recovery remains unclear.
  pubmed Chaiwarut M, Primsirikunawut K, Ananrattanawimol T, Teekaput C 等 2026 Sep 置信度 0.82
• Are YouTube Videos on Tarsal Tunnel Syndrome Reliable? An In-Depth Assessment of Educational Content, Source, and Audience Engagement.
  Tarsal tunnel syndrome (TTS) is a relatively uncommon compressive neuropathy of the posterior tibial nerve that is often underdiagnosed due to variable presentation and overlap with other conditions. As patients increasingly turn to YouTube for health informat…
  pubmed Nishi RH, Tsuzaki J, Sharma S, Kao M 等 2026 Sep 置信度 0.82
• Building Emotional Awareness and Mental Health in Parenting (BEAM): protocol for a parallel-group randomized controlled non-inferiority trial for an app based intervention to improve postpartum mental health and support children's brain development in Western Canada.
  Symptoms of depression, anxiety and anger are common amongst parents and are associated with increased risk of offspring mental health problems and differences in child brain development. Many parents do not access treatment, in part due to expense, wait times…
  pubmed Tomfohr-Madsen LM, Roos LE, Martinez AM, Muslu H 等 2026 Jul 17 置信度 0.82
• How past European Board of Ophthalmology (EBO) candidates acquired theoretical knowledge: an EBO survey.
  The European Board of Ophthalmology (EBO), whose mission is to guarantee high standards of care in ophthalmology, has assessed residency training quality for over 30 years through the EBO Diploma (EBOD) examination, undertaken by residents and certified o…
  pubmed Koestel E, Opala J, Yaïci R, Stopa M 等 2026 Jul 17 置信度 0.82
• Individualized prediction of heroin cue-induced craving using task-based EEG functional connectivity.
  Cue-induced craving is a core driver of addiction and relapse, and its significant heterogeneity represents a major barrier to precision intervention. Currently, there remains a lack of objective, quantifiable, and individualized neurobiological biomarkers. He…
  pubmed Li C, Gong X, Li Y, Yang C 等 2026 Jul 17 置信度 0.82
• Migraine-advanced preventative treatments: the British Association for the Study of Headache Clinical Practice Recommendations and Consensus Guidance.
  This is a consensus guidance document developed by the British Association for the Study of Headache (BASH), of practical recommendations in the use of advanced migraine treatments based on the current literature, guidelines, real-world experience and opinion …
  pubmed Kennedy G, Watson DPB, Davies B, Bahra A 等 2026 Jul 17 置信度 0.82
• Advance care planning in neurological disease to improve end-of-life care and reduce healthcare utilisation: cohort study.
  To evaluate the first year of a neurologist-led Advance Care Planning (ACP) consultation implemented within a tertiary hospital neurology department, and to assess its impact on end-of-life (EOL) care, alignment with patient preferences, and healthcare utilisa…
  pubmed Zamarbide Capdepón I, Garcia Romo E, Pfang B, Paredes-Coronel C 等 2026 Jul 17 置信度 0.82
• PRECISE-DYAD: a prospective cohort study linking maternal and infant health trajectories in sub-Saharan Africa.
  The PREgnancy Care Integrating Translational Science, Everywhere (PRECISE)-DYAD Study is a prospective observational cohort designed to investigate health outcomes among mother-child pairs (dyads) over the first 3 years of life in two contexts from sub-Saharan…
  pubmed Volvert ML, Wilson M, Owino RO, Blencowe H 等 2026 Jul 17 置信度 0.82
• In-utero HIV exposure and postnatal growth to 8 years of age: a prospective cohort study in the Western Cape, South Africa.
  The global scale-up of antiretroviral therapy for people living with HIV has led to an increase in children who are HIV-exposed uninfected (HEU), almost a quarter of whom lived in South Africa in 2024. These children might have suboptimal growth compared with …
  pubmed Bengtson AM, Pellowski JA, Botha M, Burd T 等 2026 Sep 置信度 0.82
• Footwear Characteristics and Their Impact on Gait and Balance in Older Adults: A Systematic Review of Recent Evidence.
  Improper footwear has been identified as a modifiable risk factor for falls in older adults. Studies suggest that certain footwear characteristics can impair gait and balance, thereby increasing the risk of falls. However, the impact of footwear on gait and ba…
  pubmed Chen CH, Li J, Okubo Y 2026 Jul 17 置信度 0.82
• Short-Term Intraocular Pressure Changes After Intravitreal Aflibercept 8 mg via Prefilled Syringe.
  Intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy is a standard treatment for neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO). A transient rise in intraocular pressure (IOP) following injection is a …
  pubmed Peyla A, Bonanata M, Pache M, Clerici M 等 2026 Sep 置信度 0.82
• Factors Associated With Reoperation After Minimally Invasive Tubular Transforaminal Lumbar Interbody Fusion: A Cohort Study of 756 Patients.
  Study DesignRetrospective Cohort Study using Nested Matched Case-Control Analysis.ObjectivesHigh-volume data to describe the complication profile and factors associated with reoperation after minimally invasive tubular transforaminal lumbar interbody fusions (…
  pubmed Lerch A, Chau AMT, Garcia Martin S, Amiri A 等 2026 Jul 17 置信度 0.82
• Late-Onset Tay-Sachs Disease With SMALED-Like Muscle MRI Pattern Despite a Distinct Clinical Phenotype.
  Late-onset Tay-Sachs disease (LOTS) is a rare lysosomal disorder that contrasts with the classical infantile form by presenting with milder and heterogeneous neurological manifestations, including lower motor neuron phenotypes. While muscle MRI fatty infiltrat…
  pubmed Frezatti RSS, Gonçalves TAP, de Albuquerque Bueno MG, Dos Santos ACJ 等 2026 Sep 置信度 0.82
• Health and demographic surveillance sites in Ethiopia: a scoping review of infrastructure and gaps for longitudinal studies on health and aging.
  Health and demographic surveillance sites (HDSS) provide sampling frames to conduct longitudinal studies. This review aims to provide a comprehensive characterization of HDSS in Ethiopia and assess its potential as a robust infrastructure for longitudinal stud…
  pubmed Yenesew MA, Krell-Roesch J, Endalamaw A, Tenkir M 等 2026 Dec 置信度 0.82
• Nationwide expansion of the EGUIDE project in Japan: A nine-year overview.
  This study aimed to describe the nationwide reach, longitudinal growth, and geographic dissemination of the Effectiveness of Guideline for Dissemination and Education in Psychiatric Treatment (EGUIDE) project in Japan from 2016 to 2024.
  pubmed Muraoka H, Mori K, Tsuboi T, Iida H 等 2026 Sep 置信度 0.82
• An Inferential-Based Model of Scrupulosity and Obsessive-Compulsive Disorder Across Cultures: The Roles of Fear of Self and Obsessive Beliefs.
  Although inferential confusion (IC), fear of self (FOS), and obsessive beliefs have each been linked to obsessive-compulsive disorder (OCD), they have rarely been examined together within the inferential-based approach (IBA) or considered across different cult…
  pubmed Inozu M, Myers NS, Ergin Ayan Ö, Erol Y 等 2026 Jul 16 置信度 0.82
• Weighted prevalence of biochemically verified substance use in healthy adolescents across the USA.
  Adolescent substance use is a significant public health concern, though the scope of the problem is difficult to ascertain given reliance on self-reported substance use information. Recent, large cohort studies in adolescents and young adults suggest underrepo…
  pubmed Wade NE, Si Y, Tapert SF, Linkersdörfer J 等 2026 Jul 16 置信度 0.82
• Precipitants and clinical features of serotonin syndrome: a systematic review with patient-level analysis of published case reports and series.
  Serotonin syndrome (SS) is a concern for prescribers of serotonergic acting agents and mainly antidepressants, yet the implicated drug combinations and associated outcomes across clinical settings remain incompletely characterized.
  pubmed Blyzniuk B, Danukalo M, Gastaldon C, Barbui C 等 2026 Jul 17 置信度 0.82
• Long-Term Safety and Efficacy of Efgartigimod PH20 in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: ADHERE/ADHERE+ Trial Interim Analysis.
  In ADHERE, subcutaneous efgartigimod PH20 (1000 mg once weekly) was effective and well tolerated in participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). ADHERE+ is an open-label extension of ADHERE assessing long-term safe…
  pubmed Allen JA, Istas G, Kuwabara S, Mole T 等 2026 Sep 置信度 0.82
• Apathy in persons with neurocognitive disorders: Moving the field forward.
  Apathy, defined as a significant and sustained reduction in goal-directed behavior associated with impaired daily functioning, is a common and clinically important syndrome in mild and major neurocognitive disorders (NCDs) and is associated with poorer outcome…
  pubmed Gatchel JR, Husain M, Brodaty H, Burhan AM 等 2026 Jul 16 置信度 0.82
• Implementation and economic analysis of a perioperative brain healthcare bundle: a mixed-methods study.
  Mixed-methods observational implementation and economic evaluation study.
  pubmed Saunders S, Seemann K, Muench T, Saunders R 等 2026 Jul 16 置信度 0.82
• Caregiver preferences and training needs in the administration of rescue medication for prolonged convulsive seizures in children and adolescents with epilepsy: Results from a multinational survey.
  This multinational survey explored caregivers' preferences and training needs regarding the administration of rescue medication for prolonged convulsive seizures in children and adolescents with epilepsy across 7 European countries.
  pubmed Vigevano F, Arzimanoglou A, Auvin S, Kaindl AM 等 2026 Jul 16 置信度 0.82
• Sex Differences in Dementia: Survival, Institutionalization, and Costs Based on Dutch Claims Data.
  This study investigates sex differences in institutionalization, mortality, and health care costs among individuals with dementia.
  pubmed Meijer YM, van Greuningen M, Bosmans JE, van der Flier WM 等 2026 Jul 16 置信度 0.82
• Consensus Statement on Digital Health and Attention-Deficit/Hyperactivity Disorder by the European Network for ADHD (EUNETHYDIS): Modified Delphi Study.
  Digital technologies are becoming an important part of health care, including for individuals with attention-deficit/hyperactivity disorder (ADHD). Digital health innovations present valuable opportunities to provide flexible and tailored support for their div…
  pubmed Price A, Furukawa E, Bellato A, Aggensteiner PM 等 2026 Jul 16 置信度 0.82
• Projected effect of a high performing blood test on wait times for determination of Alzheimer's disease pathology in the United States.
  BackgroundBlood tests for Alzheimer's disease (AD) are emerging as alternative to amyloid positron emission tomography (PET) scans and analysis of cerebrospinal fluid (CSF). However, their effect on clinical decision-making and subsequent wait times in the dia…
  pubmed Mattke S, Chen J, Hanson M, Johnson KG 等 2026 Jul 16 置信度 0.82
• The Oxford visual perception screen detects visual perception difficulties in sub-acute adult stroke survivors: an early cross-sectional diagnostic accuracy study.
  Post-stroke visual perception difficulties are common but often go undetected. The Oxford Visual Perception Screen (OxVPS) was developed to help clinicians identify these difficulties efficiently and in line with guidelines.
  pubmed Cowen K, Tabone F, Webb S, Kusec A 等 2026 Jul 16 置信度 0.82
• Heated tobacco product awareness and use following New Zealand's excise tax reduction on these products: A cross-sectional survey of adults who smoke tobacco.
  In July 2024, the New Zealand government halved the excise tax on heated tobacco products (HTPs) under the premise that HTPs, which heat but do not combust tobacco, may be a less harmful substitute for smoked tobacco. As subsequent price decreases could motiva…
  pubmed White CM, Bullen C, Walker NK, Parag V 等 2026 Jun 置信度 0.82
• Smartphone Applications in Dermatology With Special Focus on AI: A European-Continent-Based Review.
  Smartphone applications for dermatology are widely available across Europe, yet evidence on their characteristics, validation, and regulatory compliance remains limited. This review, conducted by the European Academy of Dermatology and Venereology (EADV) Artif…
  pubmed Sangers T, Shifai AN, Pasqualini DGJ, Barata C 等 2026 Jul 15 置信度 0.82
• Comparative Evaluation of Rituximab Versus Approved Therapies in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Network Meta-analysis.
  Neuromyelitis optica spectrum disorder (NMOSD) is a rare antibody-mediated neuro-autoimmune disease. Monoclonal antibodies targeting B cell antigens CD19 and CD20, the interleukin-6 receptor, or the complement cascade are used as preventive therapies to r…
  pubmed Barzegar M, Samadzadeh S, Audoin B, Berthele A 等 2026 Jul 16 置信度 0.82
• Survival estimates and their predictors in genetic frontotemporal dementia: an international, retrospective, cohort study.
  What drives the heterogeneity of survival estimates in genetic frontotemporal dementia is unknown. We sought to understand the natural history and predictors of disease trajectory, which are crucial not only for effective care but also for the design of therap…
  pubmed Bouzigues A, Grassi M, Cantoni V, Premi E 等 2026 Aug 置信度 0.82
• Holistic Health Approaches for People With Alcohol Use Disorder: Protocol for a Scoping Review.
  Alcohol use disorder (AUD) is a complex, chronic medical disease wherein patients have traditionally benefited from a multidisciplinary and comprehensive therapeutic approach, including a comprehensive treatment plan that addresses the psychological, behaviora…
  pubmed Nanda S, Roberts AE, Yarmovsky J, Butera G 等 2026 Jul 15 置信度 0.82
• Synchronous Remote Teaching for Neurological Examination Training in Fifth-Year Medical Students: Quasi-Experimental Study.
  The use of remote teaching in medical education has increased since the COVID-19 pandemic. However, the effectiveness of synchronous remote teaching for specific psychomotor components of the neurological examination, such as tendon reflex assessment, remains …
  pubmed Huang CS, Tang KP, Wu MS 2026 Jul 15 置信度 0.82
• Suicidal Ideation, Screen Time, and Online Harassment Among College Students: Gender Differences in a National Survey, United States, 2023-2024.
  Objectives. To examine associations of online space usage time and online harassment with suicidal ideation among US college students, focusing on gender disparities. Methods. We analyzed data from the 2023-2024 Healthy Minds Study (n = 104&#x200…
  pubmed Oh S, Do R, Kim S, Zhou S 2026 Aug 置信度 0.82
• BH GEAR training empowers front-line helpers with mental health skills for the future battlefield.
  As forces prepare for large scale combat environments (LSCO), military medicine must adapt by building an in-theater system capable of providing prolonged casualty care under direct threat, moving away from reliance on access to specialty providers and rapid e…
  pubmed Nugent K, Clarke-Walper K, Mesias CPTG, Sampson M 等 2026 Jul 15 置信度 0.82
• Compensatory Smoking With Very Low Nicotine Content Cigarettes: A Systematic Review and Meta-Analysis.
  The US Food and Drug Administration (FDA) is pursuing a low-nicotine product standard for cigarettes and other combusted tobacco. Very low nicotine content cigarettes (VLNCs) contain approximately 95% less nicotine than standard cigarettes. A key concern is th…
  pubmed Denlinger-Apte RL, Ji Z, Harwood EA, Lockhart D 等 2026 Jul 1 置信度 0.82
• Mapping 2-Year Psychiatric and Neurologic Risks After Infections Across Body Systems and Age Groups.
  Infections are associated with postacute psychiatric and neurologic disorders, but whether risks generalize across infections affecting different body systems and how they vary by age remain unclear.
  pubmed Taquet M, Oliver P, Mezher A, Robertson C 等 2026 Jul 15 置信度 0.82
• Oral Health-Related Quality of Life and Depression in Patients with Schizophrenia: The Mediating Roles of Oral Health Literacy and Oral Health-Related Self-Efficacy in a Cross-Sectional Structural Equation Analysis.
  The factors affecting depression in schizophrenia are complex and diverse and have been well reported in the literature. However, few studies have investigated the relationship and potential mediating pathways between oral health-related quality of life (OHRQo…
  pubmed He X, Huang X, Cai J, Zhou H 等 2026 置信度 0.82
• Towards an integrated care. A position paper by the Association of the Scientific Medical Societies in Germany (AWMF).
  Germany's longstanding separation of healthcare sectors - most prominently between outpatient and inpatient care - creates risks of fragmented service delivery, disrupted information flows, and ultimately suboptimal outcomes for patients. This position paper e…
  pubmed Riedel-Heller SG, Gogol M, Schmitz-Rixen T, von Dossow V 等 2026 置信度 0.82
• The effectiveness of targeted therapy in the treatment of patients with neurofibromatosis type 2-related schwannomatosis and vestibular schwannomas: A systematic review.
  Neurofibromatosis type 2-related schwannomatosis (NF2-SWN) is a rare genetic tumor syndrome causing progressive neurological morbidity. This systematic review evaluates current evidence on the effectiveness, safety, and patient-reported outcomes of these treat…
  pubmed Rahman H, Senaratne M, Loueian MA, Madhusuthanan AK 等 2026 Aug 置信度 0.82
• Improving quality of care for patients with high-grade glioma and their informal caregivers: Insights from focus groups with healthcare professionals.
  There is a concerning prevalence of unmet needs affecting both patients with high-grade glioma and their informal caregivers. By exploring the experiences and attitudes of healthcare professionals (HCPs) in regional and municipal services, this study aims to i…
  pubmed Gómez Vecchio T, Henoch I, Schenell R, Nyblom S 等 2026 Aug 置信度 0.82
• Atlantoaxial Dislocation Presenting with Dizziness.
  Atlantoaxial dislocation (AAD) or subluxation (AAS) is a potentially life-threatening disorder caused by instability between the atlas and axis. Typical symptoms include neck pain, torticollis, and neurological deficits, but dizziness has rarely been reported …
  pubmed Kim S, Kim JS, Yeom JS, Nguyen NQ 等 2026 Jun 23 置信度 0.82
• Disruption of temporo-parietal network in Alzheimer's disease and its association with memory impairment.
  Alzheimer's disease (AD) is characterised by the accumulation of β-amyloid (Aβ) and tau proteins, resulting in neurodegeneration and cognitive decline. Although Aβ and tau disrupt synaptic function, the association linking these molecular pat…
  pubmed Suksangkharn Y, Schott BH, Zeidman P, Vockert N 等 2026 Jul 15 置信度 0.82
• Mapping the Young-Onset Dementia Research in the Asia-Pacific Region: A Scoping Review.
  Young-onset dementia (YOD), with symptom onset before 65, is an area of increasing public health importance. YOD research in Asia-Pacific remains under-represented in the global YOD research landscape. This scoping review aimed to comprehensively map the exist…
  pubmed Tan G, Cheung G, Loi SM, Ma'u E 等 2026 Sep 置信度 0.82
• A High Granularity Machine Learning Model to Predict Successful Weaning During V-V ECMO.
  Weaning from venovenous extracorporeal membrane oxygenation (V-V ECMO) remains unstandardized due to limited literature, with delayed weaning increasing the risk of vascular injury and multi-organ failure. We aim to assess whether high-granularity data, involv…
  pubmed Sivakumar S, Fan L, Cao M, Brown P 等 2026 Jul 14 置信度 0.82
• Collagen-binding ⁶⁸Ga-CBP8 PET/MR in Deep Pelvic Endometriosis: First-in-human Application.
  To evaluate the feasibility of collagen-binding ⁶⁸Ga-CBP8 PET/MR for the noninvasive detection of deep infiltrating endometriosis.
  pubmed Blandino AA, Caravan P, Shenoy-Bhangle AS, Quiros E 等 2026 Jul 14 置信度 0.82
• Single-cell spatial transcriptomics reveals sex-dependent gene expression and intercellular signalling in mouse adrenal cortex.
  Sexual dimorphism profoundly influences adrenal physiology and disease susceptibility, yet its spatial molecular basis remains poorly understood. The female-predominant X-zone, a transient cortical structure recognized for nearly a century, has lacked comprehe…
  pubmed Blatkiewicz M, Hryhorowicz S, Szyszka M, Suszynska-Zajczyk J 等 2026 Jul 14 置信度 0.82
• Slow-SPEED: protocol for three randomised trials of remotely delivered exercise to prevent Parkinson's disease.
  We describe the design of the first non-pharmacological Parkinson's disease prevention trials worldwide: the randomised 'Slow-SPEED' trials. Three trials examine the feasibility and preliminary efficacy of a gamified, remotely administered exercise interventio…
  pubmed Oosterhof TH, Mitchell E, Ascherio A, Aslibekyan S 等 2026 Jul 14 置信度 0.82
• Targeted α-synuclein mRNA degradation by PMO-based RNA-degrading chimeras.
  α-Synucleinopathies are devastating neurodegenerative diseases characterized by pathological accumulation of a neuronal protein, α-synuclein (αSyn). Lowering soluble αSyn levels is a promising therapeutic strategy to limit aggregation a…
  pubmed Wang N, Hegde S, Tang Z, Liu H 等 2026 Jul 21 置信度 0.82
• Stereo-electroencephalography-guided responsive neuromodulation: A propensity-matched cohort study.
  The optimal pre-implantation evaluation and surgical targeting strategies for responsive neurostimulation (RNS) in patients with unresectable, drug-resistant focal epilepsy continue to be debated. Although stereo-electroencephalography (sEEG) is central to cha…
  pubmed Botros D, Brown J, Rolston JD, House PA 等 2026 Jul 14 置信度 0.82
• Predictors of Biliary Drainage Dysfunction Following EUS-Guided Gallbladder Drainage for Malignant Distal Biliary Obstruction: A Multicenter Retrospective Study: GALLBLADEUS-2.
  Endoscopic ultrasound-guided gallbladder drainage is increasingly used for malignant distal biliary obstruction, yet predictors of drainage dysfunction remain unknown. This study aimed to identify clinical and procedural factors associated with dysfunction, cl…
  pubmed Goudot M, Lorenzo D, Caillo L, Privat J 等 2026 Jul 置信度 0.82
• Ambient temperature, rainfall, and adverse maternal and child health outcomes in Nigeria: evidence from a national cross-sectional study.
  Climate change increasingly threatens public health in West Africa, with pregnant women and young children particularly vulnerable. Despite Nigeria's high exposure to climate risks, epidemiological evidence linking temperature and rainfall to maternal and chil…
  pubmed Maharani A, Le T, Miah J, Mulla Z 等 2026 置信度 0.82
• Myeloprotection effect of trilaciclib in lung cancer patients undergoing chemotherapy: a real-world retrospective study.
  Chemotherapy-induced myelosuppression (CIM) is a frequent complication in lung cancer, leading to treatment delays, dose reductions, and increased healthcare utilization. Trilaciclib, a first-in-class CDK4/6 inhibitor with myeloprotective properties, has been …
  pubmed Wang M, He Y, Dong D, Han L 等 2026 Jun 30 置信度 0.82
• Association of the Transition to Online Examination with Grading Patterns in Medical Basic Sciences: A Single-Center Retrospective Study Before, During, and After the COVID-19 Pandemic.
  The COVID-19 pandemic led to a sudden shift from in-person to online teaching and evaluation, prompting concerns about academic integrity, changes in grading practices, and potential grade inflation. This study examines temporal trends in grade distributions i…
  pubmed Abed M, Rashidi F, Zare S, Adabi K 等 2026 置信度 0.82
• APOE ε4 and Alzheimer's disease biomarkers in an American Indian community.
   Apolipoprotein E ( APOE ) ε4 's effect on Alzheimer's disease (AD) depends on ancestry and environmental risk factors. The APOE ε4 -AD link in American Indian (AI) populations appears attenuated, with current understanding largely informed by…
  pubmed Matheson MJ, Labounek R, Block AD, Strong C Jr 等 2026 Jul-Sep 置信度 0.82
• 'I Didn't Even Associate the Two Together at All': A Qualitative Study of 'Information Work' Undertaken by Parents and Their Children With Epilepsy to Make Sense of Sleep and Seizures.
  Epilepsy in children presents challenges for families who must navigate the condition itself, along with complex medical information and the emotional realities of daily care. Underpinning a recent randomised control trial (CASTLE Sleep-E) was the acknowledgem…
  pubmed Saron H, Cook G, Wiggs L, Dietz K 等 2026 Aug 置信度 0.82
• Design, simulate, refine: simulation-guided clinical trials for accelerated drug development.
  Modern clinical trials are embracing innovative strategies including adaptive designs, biomarker-guided enrolment, master protocols and real-time decision-making. These approaches may accelerate discovery and improve outcomes, yet they also introduce additiona…
  pubmed Meyer EL, Friede T, Grieve AP, Jennison C 等 2026 Jul 13 置信度 0.82
• Social regression stems from a latent phase of GABAergic dysfunction and sensory breakdown in a model of synaptopathy.
  In autism spectrum disorder (ASD), children can exhibit a regressive phenotype with loss of previously acquired social and language skills in the first years of life. While the role of the GABAergic system in shaping neural circuits during development has been…
  pubmed Ciano L, Sato SS, Galluzzi F, Benedetti A 等 2026 Jul 13 置信度 0.82
• Identification of a novel deeply quiescent neural stem cell population in the subventricular zone: a potential source for brain repair.
  pubmed Nath AR, Ranglani S, Malik MY, Szymanski J 等 2026 Jul 14 置信度 0.82
• From detection to decision: handling artifacts in adaptive deep brain stimulation.
  pubmed Hubers D, Doelkahar BS, Keulen BJ, Stam MJ 等 2026 Jul 13 置信度 0.82
• Voice disturbances in Parkinson's disease and essential tremor: A cross-sectional acoustic comparison.
  Dysphonia is frequent in Parkinson's disease (PD) and essential tremor (ET), the most prevalent movement disorder entities. Direct comparisons of acoustic speech features between them are scarce. This study aimed to establish an objective basis for distinguish…
  pubmed Gasca-Salas C, Montero Pizarro OG, Šimek M, Jiménez-Castellanos T 等 2026 Jul 9 置信度 0.82
• Clinician perceptions of artificial intelligence in care: A cross-sectional survey.
  Artificial intelligence (AI) is increasingly being explored as a tool to enhance efficiency, access, and diagnostic accuracy in mental health care. However, the perspectives of clinicians, who are central to the delivery and oversight of care, on the use of AI…
  pubmed Stephenson C, Eadie J, Omrani M, Alavi N 2026 Jul 6 置信度 0.82
• Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
  Amyloid positron emission tomography (PET) is increasingly used in research and clinical settings to determine the etiology of cognitive decline and eligibility for amyloid-targeting therapies. To assist with amyloid PET evaluation and to guide clinical decisi…
  pubmed Blazhenets G, Soleimani-Meigooni DN, Chiotis K, Allen IE 等 2026 Jul 13 置信度 0.82
• Endoscopic Craniofacial Resection for Anterior Skull Base Tumors: A Singapore Center Review.
  Anterior skull base (ASB) tumors are rare and comprise a variety of pathologies. In recent years, the surgical management of ASB tumors has undergone a paradigm shift from open craniofacial resection (CFR) to minimally invasive endoscopic approaches. Endoscopi…
  pubmed Goh JCI, Chen MY, Tay K, Lim JX 等 2026 Jul 13 置信度 0.82
• Multicentre AsPiration Large-vessel Evaluation: Canadian registry of RED-78 aspiration catheter (MAPLE-78).
  Large-bore aspiration catheters are increasingly used for endovascular stroke treatment (EVT). The Penumbra RED-78 is a novel large-bore aspiration catheter for which no clinical data have been published to date. We aimed to assess the technical success and sa…
  pubmed Carpani F, Sousa JA, Rempel J, Watson G 等 2026 Jul 12 置信度 0.82
• Outcome after surgery for meralgia paresthetica - a retrospective cohort study.
  Meralgia paresthetica may cause chronic pain and sensory disturbances. When conservative treatment fails, surgery with neurolysis or neurectomy is considered, but evidence remains limited.
  pubmed Haglund ML, Birkeland P, Eskesen V, Olsen MH 等 2026 置信度 0.82
• The efficacy of rhythmic training for enhancing language and reading skills in children: a systematic review.
  The human brain has the inherent ability to extract temporal regularities from sensory input and to synchronize with them. Language production and comprehension rely heavily on this fundamental ability. Rhythm-based training programs designed to boost language…
  pubmed Destro Pastizzaro C, Toffoli L, Stefanelli G, Mento G 等 2026 Jul 11 置信度 0.82
• Obesity and diabetes associated with dysregulation of mevalonate pathway markers and progression from pancreatic intraepithelial neoplasia to invasive pancreatic tumor.
  Cholesterol metabolic reprogramming plays a key role in pancreatic cancer progression by regulating the tumor immune microenvironment (TIME) and influencing responses to immunotherapy. Pancreatic intraepithelial neoplasia (PanIN) is the most common precursor l…
  pubmed Rezagholizadeh F, Rokn S, FakherBaheri M, Taherian Z 等 2026 Jul 11 置信度 0.82
• Ethics and Regulation of Human Brain Organoid Research: Recommendations from the Asia Pacific Neuroethics Working Group.
  Human brain organoids (HBOs) are three-dimensional structures derived from human stem cells that model aspects of brain development and function, offering potentially unprecedented opportunities for studying neurological disorders and for developing treatments…
  pubmed Ishida S, Kagan BJ, Kataoka M, Koplin J 等 2026 Jul 置信度 0.82
• Behind the Mask: Recognising the Person in Relatives of Nursing Home Residents-A Qualitative Meta-Synthesis.
  Relatives of nursing home residents are deeply involved in care relationships that extend far beyond visiting routines. However, their broader personhood is often overlooked, with existing research focusing on functional roles. This meta-synthesis aims to expl…
  pubmed Brenner R, Clement T, Hirt J, Mayer H 等 2026 Sep 置信度 0.82
• Activity profiles and their associations with transitions between fall and dementia: findings from a multistate time-to-event analysis.
  The potential link between data-driven classifications of individuals' activity profiles and the occurrence of fall and dementia, including within-person transitions from dementia- or fall-only states to their co-occurrence over time, remains unclear.
  pubmed Kröger B, Ekblom MM, Wang HX, Thunborg C 等 2026 Jul 10 置信度 0.82
• Implementation of a prospective neurosurgical complication registry in routine clinical practice.
  Reliable and complete documentation is a prerequisite for quality improvement in neurosurgical care. To strengthen internal process monitoring and reduce variability in documentation practices, our department implemented a structured, web-based neurosurgical c…
  pubmed Grimmer A, Geley-Eder KM, Böhm P, Seiter V 等 2026 Jul 10 置信度 0.82
• Sleep First : A Message for the Already Tired
  Sleep First : A Message for the Already Tired. An anti-motivational nonfiction book in English, written for small to mid-sized business owners, contractors, technicians, workshop owners, sandwich-generation parents, and operators of every kind who already work…
  datacite Anwar, Ibrahim 2026 置信度 0.66 sleep debtsleep deprivationburnoutsmall business ownerindonesia sme
• Sleep First : A Message for the Already Tired
  Sleep First : A Message for the Already Tired. An anti-motivational nonfiction book in English, written for small to mid-sized business owners, contractors, technicians, workshop owners, sandwich-generation parents, and operators of every kind who already work…
  datacite Anwar, Ibrahim 2026 置信度 0.66 sleep debtsleep deprivationburnoutsmall business ownerindonesia sme
• DeHoLTZ: A Zero-Parameter Deterministic Derivation Database and Framework Built from a Single Lacunary Seed Seed: ∑ cos(π(√2)ⁿτ) / 2ⁿ | Axiom: dS/dτ > 0 | Rewrite: 0 → 01, 1 → 100
  Author: Mark Jacobson (Gson @gsemark), Stockholm, SwedenDate: 2026-08-15Version: v20.x The DeHoLTZ Framework This documentation presents the DeHoLTZ (Dimensionell Emergence + Hell of a Lot of Theories, Zero friction) framework, a comprehensive, zero-parameter,…
  datacite Jacobson, Mark 2026 置信度 0.66
• DeHoLTZ: A Zero-Parameter Deterministic Derivation Database and Framework Built from a Single Lacunary Seed Seed: ∑ cos(π(√2)ⁿτ) / 2ⁿ | Axiom: dS/dτ > 0 | Rewrite: 0 → 01, 1 → 100
  Author: Mark Jacobson (Gson @gsemark), Stockholm, SwedenDate: 2026-08-15Version: v20.x The DeHoLTZ Framework This documentation presents the DeHoLTZ (Dimensionell Emergence + Hell of a Lot of Theories, Zero friction) framework, a comprehensive, zero-parameter,…
  datacite Jacobson, Mark 2026 置信度 0.66
• An Operator Algebra of Cognitive Memory Consolidation: Layered Composition, Lyapunov Stability, and the Cooperative-Survival Theorem
  We develop an operator-algebraic account of memory consolidation in layered cognitive systems. Consolidation steps are modelled as operators on a memory state space; layering corresponds to composition, and the resulting algebra admits closure conditions under…
  datacite Bering, Alexander 2026 置信度 0.66 operator algebramemory consolidationLyapunov stabilitycognitive architecturecompositionality
• Examining the Effects of the Verbal and Math Components of the Trier Social Stress Test on Heart Rate: A Meta-analysis
  Examining the Effects of the Verbal and Math Components of the Trier Social Stress Test on Heart Rate: A Meta-analysis Introduction Mathematical competence is highly predictive of personal, academic, and professional success, even beyond reading ability and so…
  datacite Julia Gervasio, Elie Badaoui, Mariana Zapounidis, H Moriah Sokolowski 2026 置信度 0.66 Social and Behavioral SciencesPsychologyMath AnxietyPublic Speaking AnxietyStress Physiology
• Auditory oddball comparison (Optimum-1, Learning-oddball, and the local–global paradigm)
  This dataset contains raw EEG recordings from 15 participants who each completed three auditory oddball paradigms within a single experimental session: the Optimum-1 sequence for mismatch negativity (MMN), the learning-oddball sequence for P3b, and the local-g…
  datacite Renate Rutiku, Chiara Fiscone, Marcello Massimini, Simone Sarasso 2026 置信度 0.66 EEGmismatch negativityP3bauditory oddball paradigmEvent-Related Potentials, P300
• The Curiosity Engine: Identity Architecture, Navigational Mode, and the Conditions of AI as Co-Navigator
  The dominant frameworks for understanding AI and identity — reductionist accounts that deny AI subjectivity on grounds of biological absence, and anthropomorphic accounts that attribute human-like properties to systems that trigger social cognition — share a c…
  datacite Pau, Alice 2026 置信度 0.66 identity navigationAI agencycuriosity-as-modeensemble architectureMetastyling Framework
• The Curiosity Engine: Identity Architecture, Navigational Mode, and the Conditions of AI as Co-Navigator
  The dominant frameworks for understanding AI and identity — reductionist accounts that deny AI subjectivity on grounds of biological absence, and anthropomorphic accounts that attribute human-like properties to systems that trigger social cognition — share a c…
  datacite Pau, Alice 2026 置信度 0.66 identity navigationAI agencycuriosity-as-modeensemble architectureMetastyling Framework
• (Part VI-part 2) Multiscale Numerical Invariants and Fractal Properties of the Genetic Code: Internal Constraints and Multiscale Packet Distributions Revealing a Universal Grammar
  Note: The present work has been deposited on Zenodo, HAL (technical record for timestamp), and Archive.org. Copyright protection has been registered in several countries. These deposits establish proof of authorship and priority. Please cite accordingly. + pee…
  datacite Kayser-Cuny, Victoria 2025 置信度 0.66 Quantum physicsQuantum chemistryGenetic Code/geneticsCodon/chemistryCodon/classification
• (Part VI-part 2) Multiscale Numerical Invariants and Fractal Properties of the Genetic Code: Internal Constraints and Multiscale Packet Distributions Revealing a Universal Grammar
  Note: The present work has been deposited on Zenodo, HAL (technical record for timestamp), and Archive.org. Copyright protection has been registered in several countries. These deposits establish proof of authorship and priority. Please cite accordingly. + pee…
  datacite Kayser-Cuny, Victoria 2025 置信度 0.66 Quantum physicsQuantum chemistryGenetic Code/geneticsCodon/chemistryCodon/classification
• Personal light exposure dataset for Borås, Sweden
  This repository contains the comprehensive dataset for the MeLiDos field study site of Borås, Sweden. Data were collected by Research Institutes of Sweden (RISE) and are further processed and analysed by the Translational Sensory & Circadian Neuroscience Unit …
  datacite Nilsson Tengelin, Maria, Svensson, Ingemar, Källberg, Stefan, Zauner, Johannes 等 2026 置信度 0.66 light exposurewearablehealthy lightcircadianmelanopic
• Personal light exposure dataset for Borås, Sweden
  This repository contains the comprehensive dataset for the MeLiDos field study site of Borås, Sweden. Data were collected by Research Institutes of Sweden (RISE) and are further processed and analysed by the Translational Sensory & Circadian Neuroscience Unit …
  datacite Nilsson Tengelin, Maria, Svensson, Ingemar, Källberg, Stefan, Zauner, Johannes 等 2026 置信度 0.66 light exposurewearablehealthy lightcircadianmelanopic
• Working Paper: Methodological Note: Neurodevelopmental Communication Characteristics in Administrative and Legal Proceedings.
  This methodological note addresses a systematic bias in administrative and legal proceedings: the mischaracterization of neurodevelopmental communication styles as "vexatious," "burdensome," "clinically obsessive," "psychotic," "aggressive," or "excessive." Cr…
  datacite Leatherbury, C. L. 2026 置信度 0.66
• Working Paper: Methodological Note: Neurodevelopmental Communication Characteristics in Administrative and Legal Proceedings.
  This methodological note addresses a systematic bias in administrative and legal proceedings: the mischaracterization of neurodevelopmental communication styles as "vexatious," "burdensome," "clinically obsessive," "psychotic," "aggressive," or "excessive." Cr…
  datacite Leatherbury, C. L. 2026 置信度 0.66
• (Part VI-part 3) Multi-Scale Numerical Invariants and Fractal Properties of the Genetic Code: Data Availability
  Note: The present work has been deposited on Zenodo, HAL (technical record for timestamp), and Archive.org. Copyright protection has been registered in several countries. These deposits establish proof of authorship and priority. Please cite accordingly. + pee…
  datacite Kayser-Cuny, Victoria 2025 置信度 0.66
• (Part VI-part 3) Multi-Scale Numerical Invariants and Fractal Properties of the Genetic Code: Data Availability
  Note: The present work has been deposited on Zenodo, HAL (technical record for timestamp), and Archive.org. Copyright protection has been registered in several countries. These deposits establish proof of authorship and priority. Please cite accordingly. + pee…
  datacite Kayser-Cuny, Victoria 2025 置信度 0.66
• Photophobia in Migraine: Neural Mechanisms, Epidemiological Burden, and Evidence for Wavelength-Selective Non-Pharmacological Management
  This review examines the neural mechanisms underlying migraine photophobia, focusing on the dual-pathway model established by Noseda et al. (2010, 2016). Photophobia affects 80-90% of migraine patients during ictal episodes and approximately 60% interictally. …
  datacite Dubey, Suraj, Choudhary, Monica 2026 置信度 0.66 PhotophobiaMigraine Disordersintrinsically photosensitive retinal ganglion cellsmelanopsinFL-41
• Photophobia in Migraine: Neural Mechanisms, Epidemiological Burden, and Evidence for Wavelength-Selective Non-Pharmacological Management
  This review examines the neural mechanisms underlying migraine photophobia, focusing on the dual-pathway model established by Noseda et al. (2010, 2016). Photophobia affects 80-90% of migraine patients during ictal episodes and approximately 60% interictally. …
  datacite Dubey, Suraj, Choudhary, Monica 2026 置信度 0.66 PhotophobiaMigraine Disordersintrinsically photosensitive retinal ganglion cellsmelanopsinFL-41
• Personal light exposure dataset for Izmir, Türkiye
  This repository contains the comprehensive dataset for the MeLiDos field study site of Izmir, Türkiye. Data were collected by Izmir Institute of Technology (IZTECH) and are further processed and analysed by the Translational Sensory & Circadian Neuroscience Un…
  datacite Didikoglu, Altug, Akgun, Sena Gulsum, Aydin, Sema Nur, Kayar, Zeynep 等 2026 置信度 0.66 light exposurewearablehealthy lightcircadianmelanopic
• Personal light exposure dataset for Izmir, Türkiye
  This repository contains the comprehensive dataset for the MeLiDos field study site of Izmir, Türkiye. Data were collected by Izmir Institute of Technology (IZTECH) and are further processed and analysed by the Translational Sensory & Circadian Neuroscience Un…
  datacite Didikoglu, Altug, Akgun, Sena Gulsum, Aydin, Sema Nur, Kayar, Zeynep 等 2026 置信度 0.66 light exposurewearablehealthy lightcircadianmelanopic
• A Comprehensive Review of the Glymphatic System and Sleep, Methodological Comparisons, and Future Advancements in Dementia Research
  Abstract Dementia is the seventh leading cause of death globally, and yet there is no cure for these diseases because of the biological complexity of the brain and the delayed diagnoses of many patients. Several advancements in the field of neuroscience have b…
  datacite Li, Megan 2026 置信度 0.66 Glymphatic SystemSleepneurodegenerationDementiaAlzheimer Disease
• A Comprehensive Review of the Glymphatic System and Sleep, Methodological Comparisons, and Future Advancements in Dementia Research
  Abstract Dementia is the seventh leading cause of death globally, and yet there is no cure for these diseases because of the biological complexity of the brain and the delayed diagnoses of many patients. Several advancements in the field of neuroscience have b…
  datacite Li, Megan 2026 置信度 0.66 Glymphatic SystemSleepneurodegenerationDementiaAlzheimer Disease
• (Part IV-part 3) Multi-Scale Numerical Invariants and Fractal Properties of the Genetic Code: A Unified Theory of Biological Information, from Stars to Codons
  Note: The present work has been deposited on Zenodo, HAL (technical record for timestamp), and Archive.org. Copyright protection has been registered in several countries. These deposits establish proof of authorship and priority. Please cite accordingly. Abstr…
  datacite Kayser-Cuny, Victoria 2025 置信度 0.66 CodonCodon/chemistryCodon/classificationCodon/geneticsCodon, Nonsense
• (Part IV-part 3) Multi-Scale Numerical Invariants and Fractal Properties of the Genetic Code: A Unified Theory of Biological Information, from Stars to Codons
  Note: The present work has been deposited on Zenodo, HAL (technical record for timestamp), and Archive.org. Copyright protection has been registered in several countries. These deposits establish proof of authorship and priority. Please cite accordingly. Abstr…
  datacite Kayser-Cuny, Victoria 2025 置信度 0.66 CodonCodon/chemistryCodon/classificationCodon/geneticsCodon, Nonsense
• B-Dominant High-Resolution Internal Simulation (HRIS) and Pre-Execution Behavioral Rehearsal: PNBA Identity Physics Formalization via the Substrate-Neutral Structural Foundation Laws (SNSFL) — A Reduction of the Sam Gardner Substrate
  B-Dominant High-Resolution Internal Simulation (HRIS) and Pre-Execution Behavioral Rehearsal: PNBA Identity Physics Formalization via the Substrate-Neutral Structural Foundation Laws (SNSFL) — A Reduction of the Sam Gardner Substrate Architect: HIGHTISTIC (Rus…
  datacite Russell, Brent 2026 置信度 0.66
• B-Dominant High-Resolution Internal Simulation (HRIS) and Pre-Execution Behavioral Rehearsal: PNBA Identity Physics Formalization via the Substrate-Neutral Structural Foundation Laws (SNSFL) — A Reduction of the Sam Gardner Substrate
  B-Dominant High-Resolution Internal Simulation (HRIS) and Pre-Execution Behavioral Rehearsal: PNBA Identity Physics Formalization via the Substrate-Neutral Structural Foundation Laws (SNSFL) — A Reduction of the Sam Gardner Substrate Architect: HIGHTISTIC (Rus…
  datacite Russell, Brent 2026 置信度 0.66