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• Foreword
  In May of 1998, the neuroscience community lost a dynamic young colleague, at the pinnacle of his career, in a tragic automobile accident.
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Neural plasticity: general principles
  This chapter focuses on the functional and neural mechanisms that shape the brain architecture following postnatal experience. It describes the processes according to which developing and adult brains interact and adapt to environmental stimuli, physiological …
  crossref 2021-03-05T16:09:32Z 置信度 0.70
• Sensory deprivation and neural plasticity Cross-modal and unimodal plasticity in sensory impaired
  Early sensory deprivation in visual or auditory modality involves a process of neural reorganization through a process of unimodal or multimodal restorative plasticity. Unimodal plasticity refers to the process by which the brain areas serving the impaired sen…
  crossref 2021-03-05T16:09:32Z 置信度 0.70
• Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling
  Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural plasticity. In this regard, increasing evidence shows that molecules such as insulin, insulin-like growth factor-I, glucagon-like peptide-1, and ghrelin impact…
  crossref Marco Mainardi, Salvatore Fusco, Claudio Grassi 2015-04-21T21:08:27Z 置信度 0.70
• RETRACTION: Repressor Element 1 Silencing Transcription Factor (REST) Governs Microglia-Like BV2 Cell Migration via Progranulin (PGRN).
  europepmc 2026 置信度 0.80
• Studies of Olfactory System Neural Plasticity: The Contribution of the Unilateral Naris Occlusion Technique
  Unilateral naris occlusion has long been the method of choice for effecting stimulus deprivation in studies of olfactory plasticity. A significant body of literature speaks to the myriad consequences of this manipulation on the ipsilateral olfactory pathway. E…
  crossref David M. Coppola 2012-05-29T07:13:37Z 置信度 0.70
• Contributions of Matrix Metalloproteinases to Neural Plasticity, Habituation, Associative Learning and Drug Addiction
  The premise of this paper is that increased expression of matrix metalloproteinases (MMPs) permits the reconfiguration of synaptic connections (i.e., neural plasticity) by degrading cell adhesion molecules (CAMs) designed to provide stability to those extracel…
  crossref John W. Wright, Joseph W. Harding 2010-02-10T15:30:47Z 置信度 0.70
• Invited Speakers
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Dendritic Spine Plasticity and Cognition
  The scientific studies of dendritic spines have experienced an overwhelming growth in the last three decades. Since the primary concept that dendritic spines are sites of excitatory synaptic contact, the most recent studies have led to theoretical proposals th…
  crossref Ignacio González Burgos, Irina Nikonenko, Volker Korz 2012-05-29T03:14:04Z 置信度 0.70
• Plasticity and mTOR: Towards Restoration of Impaired Synaptic Plasticity in mTOR-Related Neurogenetic Disorders
  Objective . To review the recent literature on the clinical features, genetic mutations, neurobiology associated with dysregulation of mTOR (mammalian target of rapamycin), and clinical trials for tuberous sclerosis complex (TSC), neurofibromatosis-1 (NF1) and…
  crossref Tanjala T. Gipson, Michael V. Johnston 2012-04-30T21:00:36Z 置信度 0.70
• Physiology and Plasticity of Interhemispheric Connections
  The corpus callosum (CC for aficionados) is the largest fiber bundle in the brain and establishes connections between the hemispheres, and predominantly, but not solely, between the cortical areas. Functionally mysterious for a long time, it shared with the pi…
  crossref Matteo Caleo, Giorgio M. Innocenti, Maurice Ptito 2013-05-19T17:00:40Z 置信度 0.70
• Editorial
  This issue includes three papers on the timely topic of temporal coding in sensory systems.The papers were presented together at the symposium Dynamics of Neural Processing and Neural Codes, organized by R. Lestienne, at the 1998 meeting of the European Forum …
  crossref Susan J. Sara 2007-03-15T05:22:50Z 置信度 0.70
• Emotion and Stress
  Numerous studies have shown that postnatal handling (PH) of rat pups permanently alters hypothalamic- pituitary-adrenal (HPA) responses to stress.As adults, handled rats exhibit reduced secretion of ACTH and corticosterone in response to stress.These effects o…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Sensory Deprivation and Brain Plasticity
  Early experience plays a key role in the development of the central nervous system as the brain has to adapt continuously to environmental changes that threaten its harmonious development. This adaptation phenomenon is called brain plasticity and refers to the…
  crossref Maurice Ptito, Ron Kupers, Steve Lomber, Pietro Pietrini 2012-10-09T18:49:36Z 置信度 0.70
• Spines, Plasticity, and Cognition in Alzheimer's Model Mice
  The pathological hallmarks of Alzheimer's disease (AD)—widespread synaptic and neuronal loss and the pathological accumulation of amyloid-beta peptide (A β ) in senile plaques, as well as hyperphosphorylated tau in neurofibrillary tangles—have been known for m…
  crossref Tara Spires-Jones, Shira Knafo 2011-11-28T21:20:42Z 置信度 0.70
• Synaptic Plasticity and Learning in Animal Models of Tuberous Sclerosis Complex
  Tuberous sclerosis complex (TSC) is caused by a mutation of either the Tsc1 or Tsc2 gene. As these genes work in concert to negatively regulate the mammalian target of rapamycin (mTOR) kinase which is involved in protein translation, mutations of these genes l…
  crossref Timo Kirschstein 2012-07-15T21:02:42Z 置信度 0.70
• Plasticity of Corticospinal Neural Control after Locomotor Training in Human Spinal Cord Injury
  Spinal lesions substantially impair ambulation, occur generally in young and otherwise healthy individuals, and result in devastating effects on quality of life. Restoration of locomotion after damage to the spinal cord is challenging because axons of the dama…
  crossref Maria Knikou 2012-06-05T06:55:46Z 置信度 0.70
• Posture and Movement
  Amphibians possess most limbic centers found in mammals including the hippocampal formation (medial pallium), amygdala, septum, ventral striatum, hypothalamus, nucleus accumbens, ventral tegmental area and reticular nuclei such as the nuclei raphes and the loc…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Aging and Synaptic Plasticity: A Review
  Aging affects all systems, but the brain seems to be particularly vulnerable to the action of negative, age‐dependent factors. A gradual loss of memory functions is one of the earliest and most widespread consequences of brain aging. The causes for such impair…
  crossref Jorge A. Bergado, William Almaguer 2007-03-15T09:22:50Z 置信度 0.70
• Learning and Memory
  medial part of the hyperstriatum ventrale (IMHV).The alterations include increases in the mean length of postsynaptic density profiles of axospinous synapses and the number of N-methyl-D-aspartate (NMDA) receptor binding sites, and changes in spontaneous and e…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Attention and Perception
  It has been shown that directed attention to a behaviorally relevant visual stimulus can overcome the distracting effects of other nearby stimuli, and physiological studies suggest that the critical attentional mechanisms are located in visual areas of the ven…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Time and Space
  then placed in isolation until their own songs were analysed and compared with the tutor song and a novel song.On average, there was significant song copying.The birds were then exposed to the tutor song, or they were not exposed to a song (controls), in darkn…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Disease and Pathology
  0.87 + 0.32 at 90/s.This suggests that the integrity of PD reproduction depends on the magnitude of the stimulus that marks its onset.We investigated this relation between magnitude and temporal coding reliability in a recurrent network model.The architecture …
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• RETRACTION: Aβ-Induced Repressor Element 1-Silencing Transcription Factor (REST) Gene Delivery Suppresses Activation of Microglia-Like BV-2 Cells.
  europepmc 2026 置信度 0.80
• Functional Neuroanatomy and Neurophysiology
  In order to study the role of non cognitive components, such as motivation, attention and emotionality, in the integration of learning and memory processes, and its neural substrates a neurogenetic approach has been followed in two genetic models, the Naples H…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Learning and Memory: Pharmacology
  The influence exerted by dopaminergic pathways on glutamate transmission in cortical neurons is important regarding to the higher cognitive functions.The aim of this study was to investigate the dopaminergic effects on the glutamatergic transmission in the sen…
  crossref 2007-03-15T09:22:50Z 置信度 0.70
• Astrocytes and Developmental Plasticity in Fragile X
  A growing body of research indicates a pivotal role for astrocytes at the developing synapse. In particular, astrocytes are dynamically involved in governing synapse structure, function, and plasticity. In the postnatal brain, their appearance at synapses coin…
  crossref Connie Cheng, Mary Sourial, Laurie C. Doering 2012-07-11T21:00:31Z 置信度 0.70
• Plasticity in the Neonatal Brain following Hypoxic-Ischaemic Injury
  Hypoxic-ischaemic damage to the developing brain is a leading cause of child death, with high mortality and morbidity, including cerebral palsy, epilepsy, and cognitive disabilities. The developmental stage of the brain and the severity of the insult influence…
  crossref Eridan Rocha-Ferreira, Mariya Hristova 2016-03-07T21:01:08Z 置信度 0.70
• DNA Damage, Neurodegeneration, and Synaptic Plasticity
  This special issue includes four reviews and four original research articles focusing on the physiological and pathological role of DNA damage and repair mechanisms, synaptic plasticity, and neurodegeneration. Moreover, the emerging roles played in memory and …
  crossref Daniela Merlo, Inmaculada Cuchillo-Ibañez, Rosanna Parlato, Gerhard Rammes 2016-05-25T17:00:41Z 置信度 0.70
• Environment, Leptin Sensitivity, and Hypothalamic Plasticity
  Regulation of feeding behavior has been a crucial step in the interplay between leptin and the arcuate nucleus of the hypothalamus (ARC). On one hand, the basic mechanisms regulating central and peripheral action of leptin are becoming increasingly clear. On t…
  crossref Marco Mainardi, Tommaso Pizzorusso, Margherita Maffei 2013-07-18T18:50:17Z 置信度 0.70
• Visual Plasticity in Adults
  crossref Jiawei Zhou, Zili Liu, Simon Clavagnier, Alexandre Reynaud 等 2017-06-04T17:03:15Z 置信度 0.70
• Perineuronal Nets and CNS Plasticity and Repair
  crossref Daniela Carulli, Jessica C. F. Kwok, Tommaso Pizzorusso 2016-02-16T16:02:43Z 置信度 0.70
• Retracted: Sports Augmented Cognitive Benefits: An fMRI Study of Executive Function with Go/NoGo Task.
  [This retracts the article DOI: 10.1155/2021/7476717.].
  europepmc 2023 置信度 0.80
• Retracted: Sustained Auditory Attentional Load Decreases Audiovisual Integration in Older and Younger Adults.
  [This retracts the article DOI: 10.1155/2021/4516133.].
  europepmc 2023 置信度 0.80
• Retracted: Three Mediating Pathways of Anxiety and Security in the Relationship between Coping Style and Disordered Eating Behaviors among Chinese Female College Students.
  [This retracts the article DOI: 10.1155/2021/7506754.].
  europepmc 2023 置信度 0.80
• Retracted: Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress.
  [This retracts the article DOI: 10.1155/2016/7258201.].
  europepmc 2018 置信度 0.80
• Molecular determinants of functional voltage-gated sodium (Nav) channel diversity in mammalian central neurons.
  Voltage-gated sodium (Nav) channels are key determinants of neuronal excitability, shaping action potential waveforms, repetitive firing patterns and responses to synaptic inputs, as well as controlling the output of neural circuits and influencing short- and …
  pubmed Ransdell JL, Nerbonne JM 2026 Aug 5 置信度 0.82
• Epitranscriptomic imprints on glial cell polarization: METTL3/IGF2BP2 axis as a driver of neurodegeneration in Alzheimer's disease.
  Alzheimer's disease (AD) is a progressive neurodegenerative disorder involving synapse dysfunction, neuronal death and disorientation of cognitive processes that are caused by the accumulation of amyloid-β (Aβ) along with aberrant phosphorylation o…
  pubmed Neha, Aran KR 2026 Aug 5 置信度 0.82
• Exercise-Induced Metaplasticity: Breaking the Addiction Cycle in Methamphetamine Use Disorder.
  The high relapse rate in methamphetamine (MA) use disorder (MUD) highlights limitations in current treatment approaches. MA disrupts neural circuits underlying reward processing and executive control, inducing maladaptive neuroplastic changes that reinforce co…
  pubmed Wang D, Jin J, Hillman CH, Chang YK 2026 Aug 5 置信度 0.82
• Role of β-Arrestin2 Signaling in Neuropharmacological Effects of Psychedelic Drugs.
  Current research into the actions of psychedelic drugs is focused on 5-HT2A receptor-coupled signaling pathways, particularly β-arrestin2 signaling. Here, we investigated the involvement of β-arrestin2 in psychedelic drug-induced mouse markers of h…
  pubmed Ippolito A, Tiranti A, Hurley S, Gilmour G 等 2026 Aug 5 置信度 0.82
• The Quest for the Associative Device for Hebbian-Like LTP-The Accidental Participant.
  In 1985 Holger Wigström (now deceased) and I published a proposed scenario for the induction of hippocampal Hebbian-like LTP to explain its input specificity and cooperativity. In this scenario LTP is induced by calcium influx through voltage-dependent NM…
  pubmed Gustafsson B 2026 Sep 置信度 0.82
• p-Coumaric Acid Attenuates Lead Acetate-induced Neurotoxicity in Rats by Improving Behavioral Dysfunction and Suppressing Oxidative Stress, Neuroinflammation, Apoptosis, and Plasticity-related Molecular Alterations.
  This study evaluated the neuroprotective effects of p-coumaric acid (p-CA) against lead acetate (PbAc)-induced neurotoxicity in rats by focusing on oxidative stress, neuroinflammation, apoptosis, and neuronal plasticity. 35 male rats were randomly assigned to …
  pubmed Karaarslan T, Bolat M, Bolat İ, Orhan B 等 2026 Aug 5 置信度 0.82
• The potential of HDAC inhibitors for Alzheimer's disease.
  Alzheimer's disease is a progressive neurodegenerative condition characterized by cognitive deterioration, memory loss, and persistent neuroinflammation. Notwithstanding considerable scientific advancements, current therapy strategies predominantly address sym…
  pubmed Jain V, Bharti S 2026 置信度 0.82
• Manipulation of biological systems by self-defecting and foreign agents.
  Biological systems maintain structure and function through hierarchical control, redundancy and surveillance across scales. These same features create leverage points for agents that establish a persistent presence in host systems, including foreign agents suc…
  pubmed Shmeleva EV, Levin M 2026 Aug 4 置信度 0.82
• Environmental enrichment modulates parvalbumin interneuron deficits and plasticity-related signaling after early postnatal NMDA receptor hypofunction in male rat visual cortex.
  Sensory processing deficits in schizophrenia have been linked to dysfunction of cortical inhibitory interneurons, particularly parvalbumin-expressing (PV+) populations. NMDA receptor hypofunction during development is known to disrupt interneuron maturation, b…
  pubmed Murueta-Goyena A, Ortuzar N, Bulnes S, Lafuente JV 等 2026 Aug 4 置信度 0.82
• Culture Shapes the Neural Functional Alteration and Its Development in Children With Dyslexia: A Cross-Linguistic Meta-Analysis.
  How culture shapes brain functional alteration and its development remains poorly understood in dyslexia (DD). Hereby, we conducted a meta-analysis comparing brain activation in children across Chinese (logographic), English (deep alphabetic), and German (shal…
  pubmed Yan X, Wang Z 2026 Sep 置信度 0.82
• Brain insulin resistance as a driver of proteinopathy in neurodegeneration: from cell-type-specific mechanisms to targeted therapeutics.
  Neurodegenerative diseases are increasingly linked to systemic metabolic dysfunction, with brain insulin resistance (BIR) positioned as a central mediator. Yet translating this insight into effective therapies has proven remarkably difficult. This review argue…
  pubmed Xiang M, Cao SY, Sun XH, Hu JW 等 2026 Aug 3 置信度 0.82
• Novel neonatal hypoxic-ischemic model demonstrates glial activation and memory deficits without neuronal loss.
  Neonatal global hypoxic-ischemic cerebral injury is a leading cause of infant mortality and lifelong disability. Current rodent models do not replicate neonatal global cerebral ischemia (nGCI) and reperfusion injury. Here, we developed and characterized a rode…
  pubmed Langer KM, Tiemeier E, Harmon E, Fineberg A 等 2026 Aug 3 置信度 0.82
• Beyond the sugar coating: mucin-type O-Glycosylation as an underappreciated player in brain function and disease.
  Mucin-type O-glycosylation (O-GalNAcylation) is a structurally diverse post-translational modification (PTM) that serves as a critical molecular interface at the cell surface. Unlike well-characterized PTMs such as phosphorylation or N-glycosylation, the speci…
  pubmed Seo Y, An HJ, Lee B 2026 Aug 4 置信度 0.82
• The Dual Roles of Microglia- and Astrocyte-Derived Exosomes in Cerebral Ischemia-Reperfusion Injury: from Intercellular Communication to Therapeutic Prospects.
  Cerebral ischemia-reperfusion injury (CIRI) is a complex pathological process characterized by metabolic dysfunction, oxidative stress, neuroinflammation, and structural and functional alterations of the neurovascular unit (NVU). Across different studies, CIRI…
  pubmed Yang Z, Chen H, Zhang Z, Wei X 等 2026 Aug 4 置信度 0.82
• Activity-dependent changes in axonal action potential latency coordinated with synaptic potentiation in individual hippocampal neurons.
  Neural plasticity enables the nervous system to adapt its structure and function in response to experience. Although synaptic plasticity is a central cellular mechanism underlying learning and memory, action potential propagation along axons is also subject to…
  pubmed Yamazaki Y, Fujiwara H 2026 Aug 3 置信度 0.82
• Sleep and memory consolidation: Neural and cognitive perspectives.
  This chapter synthesizes current evidence on the role of sleep in memory consolidation, emphasizing the interplay between neural oscillations, synaptic plasticity, and cognitive processes. Sleep is conceptualized as an active state, facilitating the encoding, …
  pubmed Yasser E, Ayache L, El Khayat H, Qatanany B 等 2026 置信度 0.82
• Neural mechanisms and architecture of sleep.
  This chapter explores the neural mechanisms and architectural organization of sleep, which is essential for memory consolidation, neural plasticity, metabolic homeostasis, and cognitive function. Sleep is regulated by an integrated system of homeostatic sleep …
  pubmed Salim M, Qatanany B, Sharafkhaneh A, Rao KSJ 等 2026 置信度 0.82
• Activation and increased hippocampal GPR55 prevents cognitive deficits in male APP/PS1 mice.
  Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive decline. G protein-coupled receptor 55 (GPR55) has been linked to cognitive regulation, yet its precise role in AD pathogenesis remains unclear.
  pubmed Liang Y, Zhi T, Fan B, Wu Y 等 2026 Aug 3 置信度 0.82
• Effects of Tactile Stimulation on Barrel Cortex Receptive Fields in Female Rats.
  Experience-dependent plasticity plays a critical role in shaping neural circuits during early postnatal development. The barrel cortex is the primary somatosensory region responsible for processing whisker-derived tactile information in rodents, with each barr…
  pubmed Ahmadi BM, Hajghani MS, Sheibani V, Afarinesh MR 2026 Aug 3 置信度 0.82
• Scalp Acupuncture Combined with Exercise Induces PI3K/Akt Activation and Improves Synaptic Plasticity in Post-Stroke Spastic Rats.
  Effective treatments for post-stroke spasticity (PSS) remain limited, and the mechanism by which scalp acupuncture combined with exercise (SAE) alleviates PSS is not fully understood. This study investigated the effects of SAE in rats with PSS and explored whe…
  pubmed Zhao S, Li L, Li W, Wang C 等 2026 Jul 14 置信度 0.82
• Senescence Associated With Neurodegeneration: Simultaneous Assessment of β-gal Activity And Nissl Stain In Histological Sections of Rodent Brain.
  Cellular senescence is a physiological process characterized by irreversible cell cycle arrest that impairs tissue regeneration and function. This phenomenon has emerged as a key driver of neurodegeneration, fueled by the accumulation of senescent cells within…
  pubmed Salas-Venegas V, Ramírez-Carreto RJ, Chavarría A 2026 Jul 17 置信度 0.82
• Sensory neuron heterogeneity in neuropathic pain: implications for precision analgesia.
  Neuropathic pain remains a major clinical challenge, with limited mechanism-based treatment options. This review summarizes recent advances in sensory neuron biology, with a particular focus on the transcriptomic and functional heterogeneity of nociceptive neu…
  pubmed Haag N, Körner J 2026 Sep 1 置信度 0.82
• [Research progress of puerarin antidepressant].
  Puerarin, an isoflavonoid compound derived from TCM Puerariae Lobatae Radix, has garnered increasing attention for its potential in treating depression. By systematically reviewing relevant domestic and international research, this paper elaborated on the mult…
  pubmed You PJ, Min ZY, Liu WJ, Lyu ZY 等 2026 Jul 置信度 0.82
• [Transcriptomics study of total flavonoids from Hemerocallis citrina in improving emotional behaviors in chronic stress mice via regulating 5-hydroxytryptamine signaling pathways].
  This study aims to investigate the improving effects and potential molecular mechanisms of total flavonoids from Hemerocallis citrina(HCFs) on depression-like behaviors induced by chronic unpredictable mild stress(CUMS) in mice. The mice were randomly divided …
  pubmed Hao M, Li HY 2026 Jun 置信度 0.82
• FGF13 exerts neuroprotective effects via activation of the PI3K/AKT signaling pathway and serves as a potential biomarker for depression.
  Depression is a highly recurrent psychiatric disorder characterized by persistent low mood, anhedonia, and sleep disturbances. The clinical diagnosis of depression currently relies primarily on clinical interviews and standardized assessment scales, lacking ob…
  pubmed Hu H, Lu J, Du X, Ge P 等 2026 Jul 31 置信度 0.82
• Neuroscience in pictures: Bipolar disorder.
  Bipolar disorder is a chronic, episodic mood illness characterized by recurrent oscillations between mania, depression, and euthymia, affecting an estimated 2.4% of the global population. This pictorial review explores its pathophysiology through the case of a…
  pubmed Song SH, Powell S, Good M, Keshavan MS 2026 Jul 25 置信度 0.82
• Heterogeneity in autism - challenges and opportunities.
  Autism spectrum disorder is a heterogeneous condition marked by social communication difficulties and restricted/repetitive behaviors. Although major progress has been made over the past two decades in understanding its genetics and molecular mechanisms, effec…
  pubmed Yu X 2026 Aug 1 置信度 0.82
• Research progress of traditional Chinese medicine interventions for aging-related nervous system diseases.
  Aging-related neurological disorders, including stroke, Alzheimer's disease (AD), Parkinson's disease (PD), epilepsy, and various neuroinflammatory conditions, affect over three billion individuals worldwide and constitute leading causes of morbidity, disabili…
  pubmed Du X, Shen Z, Xu Y, Song W 等 2026 Aug 1 置信度 0.82
• Molecular and cellular mechanisms of lead-induced neurotoxicity: comparative insights from rodent and zebrafish models.
  Lead is a persistent environmental heavy metal and a potent neurotoxin that continues to threaten global public health despite regulatory restrictions. Chronic and developmental exposure, particularly during early life, leads to persistent structural and funct…
  pubmed Firdous SM, Maity D, Marick S 2026 Aug 1 置信度 0.82
• Neurotoxicity of heavy metals across the lifespan: The beneficial role of nutrition from fetus to the elderly.
  Heavy metals pose a profound threat to neurological health across all stages of human life, from prenatal development to old age. Heavy metals such as lead, mercury, cadmium, and arsenic are pervasive environmental pollutants that disrupt neural function throu…
  pubmed Otenaike TA, Farodoye OM, Olaniyan H, Teibo JO 等 2026 置信度 0.82
• Cerebral differences between roller and speed skaters: preliminary evidence for roller-to-ice talent transfer.
  Talent transfer (TT) from roller skating to speed skating is a recognized pathway for developing elite athletes. This study aimed to identify the sport-specific cerebral characteristics in these athletes by comparing their brain structure and function, thereby…
  pubmed Yan Q, Zhang K, Jiang L, Wang Y 等 2026 置信度 0.82
• A Research Protocol to Study the Dose- and Age-Dependent Effects of Breathing Low Oxygen on Enhancing Transcutaneous Spinal Stimulation-Induced Walking Function for People with Spinal Cord Injury: The BO(2)ST-II Trial.
  Improving overground walking in people with chronic, incomplete spinal cord injury (iSCI) is especially important for older adults, who now represent more than 40% of the SCI population. Age and injury appear to interact to limit neuroplasticity in spared path…
  pubmed Wall J, Nijk N, Tuthill C, Piazza N 等 2026 Jan-Dec 置信度 0.82
• Synaptic Development of Fine Spatial Scale Organization of Neuronal Orientation Tuning in Mouse Primary Visual Cortex.
  Primary sensory cortices often organize neurons with similar stimulus preference into spatially functional maps. Recent work in mouse primary visual cortex (V1) has established that neuronal tuning to the orientation of visual grating stimuli is organized into…
  pubmed Yu P, Tian GJ, Doiron B 2026 Jul 21 置信度 0.82
• Repeated restraint stress enhances visual plasticity through locus coeruleus (LC)-V1 projection in adult mice.
  Stress modulates a broad range of brain functions, including the visual system. However, the specific neural mechanisms by which stress regulates function and plasticity in the adult visual system remain unclear. This study demonstrates that repeated restraint…
  pubmed Hu H, Kuang X, Yin F, Meng W 等 2026 Jul 31 置信度 0.82
• Sympathetic Long-Term Facilitation Following Acute Intermittent Hypoxia Is Similar in the Diurnal Rest <em>vs</em> Active Phase in Vagal-Intact Rats.
  Acute intermittent hypoxia (AIH) elicits long-lasting increases in phrenic and sympathetic nerve activity, effects known as phrenic (pLTF) and sympathetic long-term facilitation (sympLTF), respectively. In anesthetized, paralyzed, vagotomized and ventilated ra…
  pubmed Butenas ALE, Mitchell GS 2026 Jul 31 置信度 0.82
• Neuromolecular biomarkers of traumatic stress: Refining diagnostic criteria and personalizing treatment for core biological symptoms in PTSD.
  Aim: The aim of this review is to assess the role of neuromolecular biomarkers in post-traumatic stress disorder (PTSD) and their usefulness in improving diagnostic accuracy and supporting personalized treatment strategies.
  pubmed Ogłodek EA 2026 置信度 0.82
• Elevating cerebellar theta oscillations boosts noninvasively induced motor plasticity.
  Matching brain stimulation to the brain's natural rhythms can drive plasticity, yet this principle has rarely been tested in humans. We targeted the cerebellum, a key hub for motor coordination and learning, using a rhythm-tuned protocol that pairs theta-frequ…
  pubmed Spampinato DA, Pezzopane V, Martino Cinnera A, Antonioni A 等 2026 Jul 31 置信度 0.82
• Corticosterone-linked microglial activity underpins sexually dimorphic neuroplasticity after ketamine anesthesia.
  Anesthesia recovery is critical for resuming normal physiological and neuronal functions; however, the mechanisms involved remain elusive. Here, we identify a female-selective corticosterone-mediated microglia-neuron interaction during ketamine anesthesia reco…
  pubmed Venturino A, Alamalhoda M, Negrello T, Jin K 等 2026 Jul 31 置信度 0.82
• End-to-End Neuromorphic Cryptosystems Using n-type Organic Optoelectrochemical Synapses.
  Cryptographic bionics, which seeks to emulate biological principles for secure information processing, remains largely unexplored at the hardware level. Here, we report an optically encrypted neuromorphic cryptosystem that utilizes an n-type organic optoelectr…
  pubmed Liu R, Duan J, He Y, Wang Y 等 2026 Jul 31 置信度 0.82
• Age-Dependent Auditory Plasticity: Critical Periods in Subcortical and Cortical Encoding.
  Auditory plasticity refers to the capacity of the auditory system to reorganize in response to experience and represents a fundamental feature of neural development. This scoping review synthesizes evidence on age-dependent plasticity at both subcortical and c…
  pubmed Uzut SE 2026 Jul 置信度 0.82
• Movement dependent neural substates within levodopa-induced dyskinesia in Parkinson's disease.
  Parkinson patients suffer from levodopa-induced dyskinesia, which occur adversely to chronic dopaminergic treatment. These abnormal involuntary movements can only partly be actively suppressed and affect quality of life. A lowered motor inhibition during hyper…
  pubmed Habets JGV, Merk T, Mathiopoulou V, Kaplan J 等 2026 Jul 31 置信度 0.82
• Molecular mechanisms of the hypothalamus miR-27a/ PRKCA pathway in regulating neuronal function and aggression-related behavior.
  The intensification of livestock production has heightened public concern about animal welfare, with aggressive behavior recognized as a key determinant of both welfare and productivity. MicroRNAs (miRNAs), which are critical post-transcriptional regulators, h…
  pubmed Chao XH, Zhang CL, Yang H, Xu QL 等 2026 Jul 18 置信度 0.82
• Hippocampal neuronal progranulin mediates estrogen‑deficiency‑induced affective vulnerability and lysosomal-autophagic dysfunction.
  Perimenopausal women typically face a heightened risk of emotional disturbances, including anxiety and depression. The estrogen decline increases vulnerability to mood disorders, but the molecular mechanisms underlying stress resilience remain unclear. Here, w…
  pubmed Ni LY, Chen TH, Jia SQ, Yang QF 等 2026 Jul 30 置信度 0.82
• Therapy-Associated Lineage Plasticity in DIPG Following Combined CDK4/6 Inhibitor, Temozolomide, and Radiation.
  Diffuse intrinsic pontine glioma (DIPG) is a highly lethal and therapeutically refractory pediatric brain tumor, and the effects of distinct disease backgrounds on treatment response and residual cell-state plasticity remain poorly understood. We evaluated abe…
  pubmed Huang Z, Jiang T, Suarez Palacios MM, Ouyang T 等 2026 Jul 30 置信度 0.82
• Brain Structural Remodeling and Longitudinal Grey Matter Changes in Adults with Chronic Cough: Evidence from A Large-Scale Longitudinal Population-Based Study.
  Chronic cough (CC) is increasingly recognized as a hypersensitivity syndrome involving maladaptive neuroregulatory changes, yet large-scale evidence regarding macro-scale structural brain alterations and their longitudinal trajectory remains scarce.
  pubmed Xie S, Zhong M, Lin Z, He L 等 2026 Aug 4 置信度 0.82
• Volumetric denoising enables high-throughput volume electron microscopy and efficient downstream analysis.
  Volume electron microscopy (VEM) enables nanometer-resolution three-dimensional (3D) visualization of biological specimens via serial sectioning and imaging. Owing to limitations of downstream analysis, VEM datasets are often acquired at slow speeds and high r…
  pubmed Chen B, Wang F, Wang H, Zhang Y 等 2026 Aug 4 置信度 0.82
• Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis.
  Cognitive manifestations, including impairments in language and executive functions, are seen in amyotrophic lateral sclerosis (ALS), but the underlying mechanisms remain unclear. We mapped prefrontal cortex regions from ALS patients by integrating spatial and…
  pubmed Petrescu J, Gouveia Roque C, Jackson CA, Daly AC 等 2026 Aug 4 置信度 0.82
• Targeting Ischemic stroke-related oxidative stress with metal nanoparticles: Mechanisms and therapeutic advances.
  Ischemic stroke is a major cause of mortality and disability, largely driven by excessive reactive oxygen species (ROS) during ischemia-reperfusion injury. Current reperfusion therapies restore blood flow but fail to effectively prevent oxidative damage or pro…
  pubmed Huang YY, Zhao YN, Bi X 2026 Aug 1 置信度 0.82
• Spatial-angular baseband delay multiply and sum beamforming with coherence factor for 3D power Doppler imaging.
  Three-dimensional power Doppler imaging (3D PDI) provides volumetric visualization of microvascular networks, but 3D PDI using matrix arrays remains limited by the small effective aperture and low element sensitivity of matrix arrays. This study proposes spati…
  pubmed Li Z, Zhang Z, Luo J 2026 Aug 2 置信度 0.82
• Phenotypic and Genetic Characterization of 64 Egyptian Children With Neuronal Ceroid Lipofuscinosis.
  Neuronal ceroid lipofuscinoses (NCLs) are the most common neurodegenerative diseases in childhood. This study aimed to investigate the phenotypic and genetic spectrum of NCLs in Egypt.
  pubmed Abdelkreem E, Sadek AA, Aladawy MA, Rezk ZN 等 2026 Jul 8 置信度 0.82
• Motor-related white matter tracts are prominently affected in primary trigeminal neuralgia.
  Primary trigeminal neuralgia (PTN) is a severe chronic pain disorder, yet whole-brain white matter microstructural alterations beyond the trigeminal nerve remain poorly understood, partly due to limitations of conventional diffusion tensor imaging in crossing …
  pubmed Pashkov A, Filimonova E, He J, Feng Y 等 2026 Aug 3 置信度 0.82
• Evolving patterns of antipsychotic use and polypharmacy for schizophrenia in Hong Kong: a 21-year longitudinal study.
  Antipsychotics are the cornerstone of schizophrenia management, with antipsychotic polypharmacy commonly observed. This study aims to evaluate the trends of antipsychotic use and polypharmacy among individuals with schizophrenia in Hong Kong.
  pubmed Deng EK, Yan VK, Leung SM, Wei Y 等 2026 Jul 29 置信度 0.82
• Glymphatic system dysfunction in chronic schizophrenia: A comparison between risperidone combined with clozapine and risperidone monotherapy.
  Despite documented brain alterations in chronic schizophrenia patients on risperidone or clozapine, differences in their effects on glymphatic function remain unclear. This study compared glymphatic function between chronic schizophrenia patients receiving ris…
  pubmed Li Y, Li H, Peng S, Chen X 等 2026 Jul 29 置信度 0.82
• Neurological outcomes 30 days after cesarean delivery under spinal anesthesia in women with moyamoya disease: A single-center retrospective case-control study (2005-2021).
  Moyamoya disease may increase vulnerability to peripartum hemodynamic changes. We hypothesized a higher 30-day incidence of stroke or transient ischemic attack after cesarean delivery under spinal anesthesia in women with moyamoya disease than in those without…
  pubmed Toyama S, Tamura A, Noguchi M, Han S 等 2026 Jul 19 置信度 0.82
• Diffusion MRI of gray matter microstructural profiles in healthy aging.
  Diffusion-weighted imaging (DWI) is a non-invasive magnetic resonance imaging (MRI) acquisition technique that can provide detailed information about brain microstructure. This methodology has historically been applied only to white matter tissue in the resear…
  pubmed Merenstein JL 2026 Aug 4 置信度 0.82
• STING inhibition alleviates post-cardiac arrest brain injury by suppressing microglia-mediated neuroinflammation via the cGAS/STING/NF-κB pathway.
  Neuroinflammation plays a pivotal role in the pathogenesis of brain injury following cardiac arrest(CA), primarily mediated by microglial activation. The stimulator of interferon genes (STING) has been demonstrated to play a pivotal role in regulating anti-tum…
  pubmed Lian YT, Pu H, Sun JF, Yuan QH 等 2026 Aug 4 置信度 0.82
• Central origin of fatigability in Myalgic encephalomyelitis/chronic fatigue syndrome revealed by multimodal neuroimaging.
  Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating chronic disease characterized by physical and mental fatigue, post-exertional malaise, muscle pain, headaches, and unrefreshing sleep. Fatigability refers to a reduction of muscular …
  pubmed Bedard P, Knutson KM, McGurrin PM, Vial F 等 2026 Jul 28 置信度 0.82
• Friends, family, and community influences on adolescent development: A review of impactful findings from the ABCD study®.
  The Adolescent Brain Cognitive Development SM (ABCD) Study was funded to investigate adolescent development across 10&#x202f;+&#x202f;years, assessing multilevel social contexts of influence and adolescent health outcomes. As such, the ABCD study has generated…
  pubmed Gonzalez MR, Silmi KP, Castillo V, Perez Y 等 2026 Jul 22 置信度 0.82
• The process of object individuation shared across visual and tactile modalities.
  Distinguishing objects from the background, a process known as Object Individuation (OI), is fundamental for us to interact with the environment and relies critically on location information across sensory modalities. Nonetheless, it remains unclear and contes…
  pubmed Lou C, Chen L 2026 Aug 4 置信度 0.82
• Establishment of four induced pluripotent stem cell lines (IGIBi028-A, IGIBi029-A, IGIBi030-A, and IGIBi031-A) from peripheral blood derived cells of Spinocerebellar ataxia Type 12 patients.
  Spinocerebellar ataxia type 12 (SCA12) is a progressive late-onset neurodegenerative disorder caused by expansion of&#xa0;&#x2265;&#xa0;43 trinucleotide CAG repeats in the upstream non-coding region of the PPP2R2B gene at locus 5q32 (SCA12; OMIM#604326). Clini…
  pubmed Ahmad I, Reza S, Singh N, Yadav S 等 2026 Jul 29 置信度 0.82
• Genomic Landscape of Phenotypes Causally Associated with Night Shift Work.
  To apply an MR-PheWAS to infer causality between NSW and multiple health outcomes.
  pubmed Jin X, Yang Y, Xu J, Liu H 2026 Aug 4 置信度 0.82
• Association of Enlarged Perivascular Spaces and Total Small Vessel Disease Burden With Kidney Function.
  Enlarged perivascular spaces (EPVSs) in the basal ganglia (BG-EPVS) are an important marker of cerebral small vessel disease (cSVD), and EPVS in the centrum semiovale (CSO-EPVS) are part of the diagnostic criteria for cerebral amyloid angiopathy. We aimed to i…
  pubmed Nash PS, Ambler G, Best JG, Wilson D 等 2026 Aug 25 置信度 0.82
• DCL-SE: Dynamic curriculum learning for spatiotemporal encoding of brain imaging.
  High-dimensional neuroimaging analyses for clinical diagnosis are often constrained by compromises in spatiotemporal fidelity and the limited adaptability of large-scale, general-purpose models. To address these challenges, we introduce Dynamic Curriculum Lear…
  europepmc 2026 置信度 0.80
• Mega-analysis of Structural Brain Imaging in Functional Neurological Disorder.
  Background Despite recent advances, the pathophysiology of functional neurological disorder (FND) remains incompletely understood. Structural neuroimaging studies have identified gray matter alterations in somatomotor-, salience-, limbic-, and default mode net…
  europepmc 2026 置信度 0.80