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• The Space Radiobiological Exposure Facility on the China Space Station.
  The Space Radiobiological Exposure Facility (SREF) is a general experimental facility at the China Space Station for scientific research in the fields of space radiation protection, space radiation biology, biotechnology, and the origin of life. The facility p…
  pubmed Zhang B, Zhong R, Shen G, Tuo C 等 2025 置信度 0.82
• Evolutionary Dynamics of RuBisCO: Emergence of the Small Subunit and its Impact Through Time.
  Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is an ancient protein critical for CO2-fixation and global biogeochemistry. Form-I RuBisCO complexes uniquely harbor small subunits that form a hexadecameric complex together with their large subunits. …
  pubmed Amritkar K, Cuevas-Zuviría B, Kaçar B 2025 Jan 6 置信度 0.82
• Dormancy in the origin, evolution and persistence of life on Earth.
  Life has existed on Earth for most of the planet's history, yet major gaps and unresolved questions remain about how it first arose and persisted. Early Earth posed numerous challenges for life, including harsh and fluctuating environments. Today, many organis…
  pubmed Webster KD, Lennon JT 2025 Jan 置信度 0.82
• Unveiling the Bioleaching Versatility of Acidithiobacillus ferrooxidans.
  Acidithiobacillus ferrooxidans is a Gram-negative bacterium that thrives in extreme acidic conditions. It has emerged as a key player in biomining and bioleaching technologies thanks to its unique ability to mobilize a wide spectrum of elements, such as Li, P,…
  pubmed Tonietti L, Esposito M, Cascone M, Barosa B 等 2024 Nov 23 置信度 0.82
• Viability and Motility of Escherichia coli Under Elevated Martian Salt Stresses.
  This study investigates the effects of three Martian-relevant salts-sodium chlorate, sodium perchlorate, and sodium chloride-on the viability and motility of Escherichia coli , a model organism for understanding microbial responses to environmental stress. The…
  pubmed Riekeles M, Santos B, Youssef SA, Schulze-Makuch D 2024 置信度 0.82
• Utilizing Martian samples for future planetary exploration-Characterizing hazards and resources.
  One of the most surprising and important findings of the first human landings on the Moon was the discovery of a very fine layer of lunar dust covering the entire surface of Moon along with the negative impacts of this dust on the well-being and operational ef…
  pubmed Whetsel C, Levine JS, Hoffman SJ, Luckey CM 等 2025 Jan 14 置信度 0.82
• Organic matter and biomarkers: Why are samples required?
  The search for evidence of past prebiotic or biotic activity on Mars will be enhanced by the return of samples to Earth laboratories. While impressive analytical feats have been accomplished by in situ missions on the red planet, accessing the capabilities of …
  pubmed Sephton MA, Steele A, Westall F, Schubotz F 2025 置信度 0.82
• Mars Sample Return: From collection to curation of samples from a habitable world.
  NASA's Mars 2020 mission has initiated collection of samples from Mars' Jezero Crater, which has a wide range of ancient rocks and rock types from lavas to lacustrine sedimentary rocks. The Mars Sample Return (MSR) Campaign, a joint effort between NASA and ESA…
  pubmed McCubbin FM, Farley KA, Harrington AD, Hutzler A 等 2025 置信度 0.82
• Photochemical pathways in astronomical ices: A computational study of singlet oxygen reactions with hydrocarbons.
  Complex organic molecules are widespread in different areas of the interstellar medium, including cold areas, such as molecular clouds, where chemical reactions occur in ice. Among the observed molecules are oxygen-bearing organic molecules, which are of high …
  pubmed Daniely A, Zamir A, Eisenberg HR, Livshits E 等 2025 置信度 0.82
• Raiding nature's genetic toolbox for UV-C resistance by functional metagenomics.
  As we assess the habitability of other worlds, we are limited by being able to only study terrestrial life adapted to terrestrial conditions. The environments found on Earth, though tremendously diverse, do not approach the multitude of potentially habitable e…
  pubmed Roberts Kingman GA, Kipness JL, Rothschild LJ 2025 置信度 0.82
• Deep terrestrial indigenous microbial community dominated by Candidatus Frackibacter.
  Characterizing deep subsurface microbial communities informs our understanding of Earth's biogeochemistry as well as the search for life beyond the Earth. Here we characterized microbial communities within the Kidd Creek Observatory subsurface fracture water s…
  pubmed Ford SE, Slater GF, Engel K, Warr O 等 2024 置信度 0.82
• Understanding Titan's Prebiotic Chemistry: Synthesizing Amino Acids Through Aminonitrile Alkaline Hydrolysis.
  Titan is an ocean world with a plethora of organic material in its atmosphere and on its surface, making it an intriguing location in the search for habitable environments beyond Earth. Settled aerosols will mix with transient surface melts following cryovolca…
  pubmed Farnsworth KK, McLain HL, Chung A, Trainer MG 2024 Dec 19 置信度 0.82
• May Antarctic plants grow on Martian and Lunar soil simulants under terrestrial conditions?
  Extremophile organisms have been largely studied in Astrobiology. Among them, two antarctic plants emerge as good candidates to become colonizers of other celestial bodies, such as Mars and the Moon. The present research aimed to evaluate survival and growing …
  pubmed Amaral CRL, Anjos D, Bones FLV, Freitas AC 等 2024 置信度 0.82
• Machine Learning Correlation of Electron Micrographs and ToF-SIMS for the Analysis of Organic Biomarkers in Mudstone.
  The spatial distribution of organics in geological samples can be used to determine when and how these organics were incorporated into the host rock. Mass spectrometry (MS) imaging can rapidly collect a large amount of data, but ions produced are mixed without…
  pubmed Pasterski MJ, Lorenz M, Ievlev AV, Wickramasinghe RC 等 2025 Jan 1 置信度 0.82
• Early Technology Readiness Level (TRL) Development of the Microfluidic Inorganic Conductivity Detector for Europa and the Solenoid-Based Actuator Assembly for Impact Penetrators.
  This study introduces an innovative in situ lander/impact-penetrator design tailored for Discovery-class missions to Europa, specifically focused on conducting astrobiological analyses. The platform integrates a microfluidic capacitively coupled contactless co…
  pubmed Govinda Raj C, Odeh M, Salyards C, Stockton A 2024 Dec 2 置信度 0.82
• An experimental and numerical model of the behavior of cytosine in aqueous solution under gamma radiation. Relevance in prebiotic chemistry.
  Cytosine is an essential chemical molecule in living systems, such as DNA and RNA, it is essential in astrobiology to study how it behaves under probable primitive conditions. We looked at how cytosine broke down in aqueous solutions exposed to high radiation …
  pubmed Paredes-Arriaga A, Negrón-Mendoza A, Frias D, Rivera AL 等 2024 置信度 0.82
• Order of amino acid recruitment into the genetic code resolved by last universal common ancestor's protein domains.
  The current "consensus" order in which amino acids were added to the genetic code is based on potentially biased criteria, such as the absence of sulfur-containing amino acids from the Urey-Miller experiment which lacked sulfur. More broadly, abiotic abundance…
  pubmed Wehbi S, Wheeler A, Morel B, Manepalli N 等 2024 Dec 24 置信度 0.82
• JWST sighting of decametre main-belt asteroids and view on meteorite sources.
  Asteroid discoveries are essential for planetary-defence efforts aiming to prevent impacts with Earth 1 , including the more frequent 2 megaton explosions from decametre impactors 3-6 . Although large asteroids (≥100 kilometres) have remained in …
  pubmed Burdanov AY, de Wit J, Brož M, Müller TG 等 2025 置信度 0.82
• Author Correction: Iron sulfide-catalyzed gaseous CO(2) reduction and prebiotic carbon fixation in terrestrial hot springs.
  pubmed Nan J, Luo S, Tran QP, Fahrenbach AC 等 2024 置信度 0.82
• Enantioselective interactions of aminonitrile dimers.
  Enantioenrichment of amino acids is essential during the early chemical evolution leading to the origin of life. However, the detailed molecular mechanisms remain unsolved. Dimerization of enantiomers is the first molecular process in the nucleation of deposit…
  pubmed Watanabe N, Komatsu Y, Miyagawa K, Hori Y 等 2024 置信度 0.82
• Living in Their Heyday: Iron-Oxidizing Bacteria Bloomed in Shallow-Marine, Subtidal Environments at ca. 1.88 Ga.
  The majority of large iron formations (IFs) were deposited leading up to Earth's great oxidation episode (GOE). Following the GOE, IF deposition decreased for almost 500 Myr. Subsequently, around 1.88 Ga, there was widespread deposition of shallow-water…
  pubmed Kovalick A, Heard AW, Johnson AC, Chan CS 等 2024 Nov-Dec 置信度 0.82
• Natural Size Variation Amongst Protocells Leads to Survival and Growth Under Hypoosmotic Conditions.
  Membrane growth is vital to the evolution of cellular life. For model protocells, this is typically achieved through competition between different protocell populations or by adding extra amphiphiles. This work demonstrates an alternative mechanism for protoce…
  pubmed Lowe LA, Kaushik NK, Wang A 2025 置信度 0.82
• Genetic Variation in the Atlantic Bobtail Squid-Vibrio Symbiosis From the Galician Rías.
  Symbiotic marine bacteria that are transmitted through the environment are susceptible to abiotic factors (salinity, temperature, physical barriers) that can influence their ability to colonize their specific hosts. Given that many symbioses are driven by host…
  pubmed Pérez-Ferrer PA, Ashraf M, Rodrigues M, Troncoso J 等 2025 Jan 置信度 0.82
• Alternative Solvents for Life: Framework for Evaluation, Current Status, and Future Research.
  Life is a complex, dynamic chemical system that requires a dense fluid solvent in which to take place. A common assumption is that the most likely solvent for life is liquid water, and some researchers argue that water is the only plausible solvent. However, a…
  pubmed Bains W, Petkowski JJ, Seager S, William Bains 等 2024 置信度 0.82
• Translation as a Biosignature.
  Life on Earth relies on mechanisms to store heritable information and translate this information into cellular machinery required for biological activity. In all known life, storage, regulation, and translation are provided by DNA, RNA, and ribosomes. Life bey…
  pubmed McKaig JM, Kim M, Carr CE, Jordan M. McKaig 等 2024 置信度 0.82
• Mesoarchean Microbial Cd, Ba, and Ni Cycling: Evidence for Photosynthesis in Pongola Group Stromatolites through Novel Stable Isotopes and High-Resolution Trace Element Maps.
  Nontraditional stable isotopes of bioactive metals emerged as novel proxies for reconstructing the biogeochemical cycling of metals, which serve as cofactors in major metabolic pathways. The fractionation of metal isotopes between ambient fluid and microorgani…
  pubmed Hohl SV, Lv Y, Lin YB, Zhang Y 等 2024 置信度 0.82
• Iron sulfide-catalyzed gaseous CO(2) reduction and prebiotic carbon fixation in terrestrial hot springs.
  Understanding abiotic carbon fixation provides insights into early Earth's carbon cycles and life's emergence in terrestrial hot springs, where iron sulfide (FeS), similar to cofactors in metabolic enzymes, may catalyze prebiotic synthesis. However, the role o…
  pubmed Nan J, Luo S, Tran QP, Fahrenbach AC 等 2024 Nov 28 置信度 0.82
• Simplified Meteorite Parent Body Alteration of Amino Acids by Hydrothermal Processes.
  Amino acids have been identified in extraterrestrial materials such as meteorites and returned samples from asteroids and comets. Some of these amino acids or their precursors may have formed on icy interstellar dust grains or at a later phase when these grain…
  pubmed Materese CK, Aponte JC, McLain HL, Farnsworth KK 等 2024 置信度 0.82
• Lightning-Driven Pyrite Oxidation Under Archean Atmosphere Conditions.
  Oxidative weathering is a major source of bio-essential micronutrients on Earth today; however, this flux would have been muted on the early Earth or on Mars, where atmospheric O 2(g) levels were very low. Here, we explore the hypothesis that nitrogen oxides g…
  pubmed Long ALS, Baidya AS, Stüeken EE, Annabel L.S. Long 等 2024 置信度 0.82
• Extremophiles and Extremophilic Behaviour-New Insights and Perspectives.
  Extremophiles, throughout evolutionary time, have evolved a plethora of unique strategies to overcome hardships associated with the environments they are found in. Modifying their genome, showing a bias towards certain amino acids, redesigning their proteins, …
  pubmed Angelakis GN, Psarologaki C, Pirintsos S, Kotzabasis K 2024 置信度 0.82
• Self-Sustaining Living Habitats in Extraterrestrial Environments.
  Standard definitions of habitability assume that life requires the presence of planetary gravity wells to stabilize liquid water and regulate surface temperature. Here, the consequences of relaxing this assumption are evaluated. Temperature, pressure, volatile…
  pubmed Wordsworth R, Cockell C, R. Wordsworth, C. Cockell 2024 置信度 0.82
• Organic Products of Fatty Acid and Magnesium Sulfate Mixtures after Gamma Radiolysis: Implications for Missions to Europa.
  If ocean-derived materials are present at Europa's surface, they would represent accessible records of ocean chemistry and habitability, but such materials would be further processed by Europa's harsh radiation environment. In this study, saturated fatty acids…
  pubmed Lewis JMT, Bower DM, Pavlov AA, Li X 等 2024 置信度 0.82
• Synthetic Ecosystems: From the Test Tube to the Biosphere.
  The study of ecosystems, both natural and artificial, has historically been mediated by population dynamics theories. In this framework, quantifying population numbers and related variables (associated with metabolism or biological-environmental interactions) …
  pubmed Solé R, Maull V, Amor DR, Mauri JP 等 2024 Dec 20 置信度 0.82
• Prebiotic Nucleoside Phosphorylation in a Simulated Deep-Sea Supercritical Carbon Dioxide-Water Two-Phase Environment.
  Prebiotic synthesis of complex organic molecules in water-rich environments has been a long-standing challenge. In the modern deep sea, emission of liquid CO 2 has been observed in multiple locations, which indicates the existence of benthic CO 2 pools. Recent…
  pubmed Tagawa S, Hatami R, Morino K, Terazawa S 等 2024 置信度 0.82
• Travel Times of a Descending Melting Probe on Europa.
  In this study, we calculated the travel times of a thermal probe that descends through Europa's ice shell. The ice column is simplified to a conductive layer. Using a cellular automaton model, the descent of the probe was simulated by tracking temperature chan…
  pubmed Carballido A, Augusto Carballido 2024 置信度 0.82
• Fatty Acid Analysis by Capillary Electrophoresis and Contactless Conductivity Detection for Future Life Detection Missions.
  Future life-detection missions will likely search for biosignatures within a wide range of organic compounds, including fatty acids. In order to determine such biosignatures, it is necessary to identify and quantify individual fatty acids present within a samp…
  pubmed Kok MGM, Mora MF 2025 置信度 0.82
• Astrochemistry: The study of chemical processes in space.
  The formation of our solar system occurred approximately 4.6 billion years ago as a result of the gravitational collapse of a small portion of a giant molecular cloud. The origin of life on Earth is yet to be fully understood. Astrochemistry plays a crucial ro…
  pubmed Das A 2024 置信度 0.82
• A multiple biomolecules-based rapid life detection protocol embedded in a rover scientific subsystem for soil sample analysis.
  The study of whether life exists, is extinct, or not depends on various sophisticated experimental studies, as many different signatures of life can be used. The experimental procedures that can be performed to identify life can be further restricted by time, …
  pubmed Zaman A, Ashraf F, Khan H, Ahona FN 等 2024 置信度 0.82
• Characterization and application of Lachancea thermotolerans isolates for sake brewing.
  Non-conventional yeasts are increasingly being used in the production of fermented beverages owing to their ability to create unique and high-quality products. The yeast Lachancea thermotolerans is of great industrial significance, particularly in the producti…
  pubmed Nakatani M, Ohtani R, Umezawa K, Uchise T 等 2025 Jan 置信度 0.82
• Methanogens and what they tell us about how life might survive on Mars.
  Space exploration and research are uncovering the potential for terrestrial life to survive in outer space, as well as the environmental factors that affect life during interplanetary transfer. The presence of methane in the Martian atmosphere suggests the pos…
  pubmed Paulchamy C, Vakkattuthundi Premji S, Shanmugam S 2024 置信度 0.82
• Eta-Earth Revisited I: A Formula for Estimating the Maximum Number of Earth-Like Habitats.
  In this hypothesis article, we discuss the basic requirements of planetary environments where aerobe organisms can grow and survive, including atmospheric limitations of millimeter-to-meter-sized biological animal life based on physical limits and O 2 , N 2 , …
  pubmed Lammer H, Scherf M, Sproß L, Helmut Lammer 等 2024 置信度 0.82
• Preface to Eta-Earth Revisited: How Common Are Earth-like Habitats in the Galaxy?
  pubmed Lammer H, Scherf M, Helmut Lammer, Manuel Scherf 2024 置信度 0.82
• Glycine synthesis from nitrate and glyoxylate mediated by ferroan brucite: An integrated pathway for prebiotic amine synthesis.
  Amino acids are present in all known life, so identifying the environmental conditions under which they can be synthesized constrains where life on Earth might have formed and where life might be found on other planetary bodies. All known abiotic amino acid sy…
  pubmed Chimiak L, Hara E, Sessions A, Templeton AS 2024 Nov 5 置信度 0.82
• Synergistic Interactions among Vacuum, Solar Heating, and UV Irradiation Enhance the Lethality of Interplanetary Space.
  A Planetary Atmospheric Chamber (PAC) was used to create simulations of interplanetary conditions to test the spore survival of three Bacillus spp. exposed to interacting conditions of vacuum (VAC), simulated solar heating (HEAT), and simulated solar ultraviol…
  pubmed Schuerger AC 2024 Sep 29 置信度 0.82
• The Cultivation of Halophilic Microalgae Shapes the Structure of Their Prokaryotic Assemblages.
  The influence of microalgae on the formation of associated prokaryotic assemblages in halophilic microbial communities is currently underestimated. The aim of this study was to characterize shifts in prokaryotic assemblages of halophilic microalgae upon their …
  pubmed Selivanova EA, Yakimov MM, Kataev VY, Khlopko YA 等 2024 Sep 26 置信度 0.82
• Alunite in Cross Crater, Mars: Evidence for a Possible Site of Ancient Life.
  Cross Crater is a 65-km impact crater located in the Noachian highlands of the Terra Sirenum region of Mars. Geochemical modeling has indicated that alunite detected on the southwest wall of Cross Crater could have been formed by a fumarole upwelling into Cros…
  pubmed Ranalli AJ, Swayze GA, Anthony J. Ranalli, Gregg A. Swayze 2024 置信度 0.82
• Aeolian Biodispersal of Terrestrial Microorganisms on Mars Through Saltation Bombardment of Spacecraft.
  A major unknown in the field of planetary protection is the degree to which natural atmospheric processes remove terrestrial microorganisms from robotic and crewed spacecraft that could potentially contaminate Mars (i.e., forward contamination). We present exp…
  pubmed Fenton LK, Marshall JR, Schuerger AC, Smith JK 等 2024 置信度 0.82
• A Machine-Learning Approach to Biosignature Exploration on Early Earth and Mars Using Sulfur Isotope and Trace Element Data in Pyrite.
  We propose a novel approach to identify the origin of pyrite grains and distinguish biologically influenced sedimentary pyrite using combined in situ sulfur isotope (δ 34 S) and trace element (TE) analyses. To classify and predict the origin of individua…
  pubmed Figueroa MC, Gregory DD, Williford KH, Fike DJ 等 2024 置信度 0.82
• Isotopic evidence of acetate turnover in Precambrian continental fracture fluids.
  The deep continental crust represents a vast potential habitat for microbial life where its activity remains poorly constrained. Organic acids like acetate are common in these ecosystems, but their role in the subsurface carbon cycle - including the mechanism …
  pubmed Mueller EP, Panehal J, Meshoulam A, Song M 等 2024 置信度 0.82
• Rapid Destruction of Lipid Biomarkers Under Simulated Cosmic Radiation.
  Understanding how organics degrade under galactic cosmic rays (GCRs) is critical as we search for traces of ancient life on Mars. Even if the planet harbored life early in its history, its surface rocks have been exposed to ionizing radiation for about four bi…
  pubmed Roussel A, Pavlov AA, Dworkin JP, Johnson SS 等 2024 置信度 0.82
• Radiation-Driven Destruction of Thiophene and Methyl-Substituted Thiophenes.
  Thiophene and two derivatives (2-methylthiophene and 3-methylthiophene) have been detected on the surface of Mars with the Sample Analysis at Mars instrument suite onboard NASA's Curiosity rover. Thiophene could serve as a secondary chemical biosignature since…
  pubmed Tribbett PD, Yarnall YY, Hudson RL, Gerakines PA 等 2024 置信度 0.82
• Self-Shielding Enhanced Organics Synthesis in an Early Reduced Earth's Atmosphere.
  Earth is expected to have acquired a reduced proto-atmosphere enriched in H 2 and CH 4 through the accretion of building blocks that contain metallic Fe and/or the gravitational trapping of surrounding nebula gas. Such an early, wet, reduced atmosphere that co…
  pubmed Yoshida T, Koyama S, Nakamura Y, Terada N 等 2024 置信度 0.82
• Volatile organic compounds (VOCs) in terrestrial extreme environments: implications for life detection beyond Earth.
  Covering: 1961 to 2024Discovering and identifying unique natural products/biosignatures (signatures that can be used as evidence for past or present life) that are abundant, and complex enough that they indicate robust evidence of life is a multifaceted proces…
  pubmed Batty CA, Pearson VK, Olsson-Francis K, Morgan G 2025 置信度 0.82
• Modeling Realistic Clay Systems with ClayCode.
  Clays are a broad class of ubiquitous layered materials. Their specific chemophysical properties are intimately connected to their molecular structure, featuring repeating patterns broken by substitutions. Molecular dynamics simulations can provide insight int…
  pubmed Pollak H, Degiacomi MT, Erastova V 2024 Nov 12 置信度 0.82
• Carotenoids dispersed in gypsum rock as a result of algae adaptation to the extreme conditions of the Atacama Desert.
  The high-altitude pre-Andean region of the Atacama Desert is characterized by its stark volcanic rock formations and unique hydrothermal gypsum outcrops (gypcrete) that it hosts. This study delves into the biomolecular composition of the endolithic phototrophi…
  pubmed Vítek P, Ascaso C, Artieda O, Wierzchos J 2024 Oct 13 置信度 0.82
• Evidence for phospholipid self-organisation in concentrated ammonia-water environments.
  Titan, the largest moon of Saturn is thought to have the potential to support primordial life. The surface of Titan contains bodies of liquid hydrocarbons, and modelling suggests that an ammonia-water ocean resides deep beneath the surface, both of which have …
  pubmed Mackay SM, Sutherland B, Easingwood RA, Hopkins A 等 2024 置信度 0.82
• Subsurface Microbial Colonization at Mineral-Filled Veins in 2-Billion-Year-Old Mafic Rock from the Bushveld Igneous Complex, South Africa.
  Recent advances in subsurface microbiology have demonstrated the habitability of multi-million-year-old igneous rocks, despite the scarce energy supply from rock-water interactions. Given the minimal evolution coupled with exceedingly slow metabolic rates in s…
  pubmed Suzuki Y, Webb SJ, Kouduka M, Kobayashi H 等 2024 置信度 0.82
• Self-Oxidation of the Atmospheres of Rocky Planets with Implications for the Origin of Life.
  Rocky planets may acquire a primordial atmosphere by the outgassing of volatiles from their magma ocean. The distribution of O between H 2 O, CO, and CO 2 in chemical equilibrium subsequently changes significantly with decreasing temperature. We consider here …
  pubmed Johansen A, Camprubi E, van Kooten E, Hoeijmakers HJ 等 2024 置信度 0.82
• Timing and Likelihood of the Origin of Life Derived from Post-Impact Highly Reducing Atmospheres.
  Big impacts on the early Earth would have created highly reducing atmospheres that generated molecules needed for the origin of life, such as nitriles. However, such impactors could have been followed by collisions that were sufficiently big to vaporize the oc…
  pubmed Wogan NF, Catling DC, Zahnle KJ, Nicholas F. Wogan 等 2024 置信度 0.82
• Advances in Extremophile Research: Biotechnological Applications through Isolation and Identification Techniques.
  Extremophiles, organisms thriving in extreme environments such as hot springs, deep-sea hydrothermal vents, and hypersaline ecosystems, have garnered significant attention due to their remarkable adaptability and biotechnological potential. This review present…
  pubmed Gallo G, Aulitto M 2024 置信度 0.82
• Quantum Markov blankets for meta-learned classical inferential paradoxes with suboptimal free energy.
  Quantum active Bayesian inference and quantum Markov blankets enable robust modeling and simulation of difficult-to-render natural agent-based classical inferential paradoxes interfaced with task-specific environments. Within a non-realist cognitive completene…
  pubmed Clark KB 2024 置信度 0.82
• Bimolecular photodissociation of interstellar 1-Cyanonaphthalene via Intermolecular Coulombic decay.
  Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in space and govern the interstellar chemistry. The two isomers of cyanonaphthalene (1-CNN and 2-CNN) were the first PAHs to be recently identified in the Taurus Molecular Cloud (TMC-1). Their large abunda…
  pubmed Dutta S, Behera NR, Barik S, Kushawaha RK 等 2024 置信度 0.82
• Exploring the potential of plant astrobiology: adapting flora for extra-terrestrial habitats: a review.
  In recent years, the realm of astrobiology has expanded beyond the search for microbial life to encompass the intriguing possibility of plant life beyond our planet. Plant astrobiology delves into the adaptations and mechanisms that might allow Earth's flora t…
  pubmed Mazhar MW, Ishtiaq M, Maqbool M, Mahmoud EA 等 2025 置信度 0.82
• Hyperexpansion of genetic diversity and metabolic capacity of extremophilic bacteria and archaea in ancient Andean lake sediments.
  The Andean Altiplano hosts a repertoire of high-altitude lakes with harsh conditions for life. These lakes are undergoing a process of desiccation caused by the current climate, leaving terraces exposed to extreme atmospheric conditions and serving as analogs …
  pubmed Lezcano MÁ, Bornemann TLV, Sánchez-García L, Carrizo D 等 2024 Sep 17 置信度 0.82
• In Situ Quantification of Carbonate Species Concentrations, pH, and pCO(2) in Calcite Fluid Inclusions Using Confocal Raman Spectroscopy.
  Carbonate minerals are globally distributed on the modern and ancient Earth and are abundant in terrestrial and marine depositional environments. Fluid inclusions hosted by calcite retain primary signatures of the source fluid geochemistry at the time of miner…
  pubmed Hudgins MN, Knobbe TK, Hubbard J, Steele A 等 2024 置信度 0.82
• Gravitational instability in a planet-forming disk.
  The canonical theory for planet formation in circumstellar disks proposes that planets are grown from initially much smaller seeds 1-5 . The long-considered alternative theory proposes that giant protoplanets can be formed directly from collapsing fragments of…
  pubmed Speedie J, Dong R, Hall C, Longarini C 等 2024 置信度 0.82
• Microbial colonization of gypsum: from the fossil record to the present day.
  Microorganisms inhabiting gypsum have been observed in environments that differ greatly in water availability. Gypsum colonized by microorganisms, including cyanobacteria, eukaryotic algae, and diverse heterotrophic communities, occurs in hot, arid or even hyp…
  pubmed Jehlička J, Oren A, Vítek P, Wierzchos J 2024 置信度 0.82
• Dehydration promotes phosphoramidate-linked amino acidyl and peptido adenosine conjugates.
  Cyclic nucleoside phosphates have been shown previously to be adequately activated to oligomerise under dry conditions. Herein, it is demonstrated that 3',5'-cyclic adenosine monophosphate (3',5'-cAMP) and glycine when subjected to dehydration under alkaline c…
  pubmed Deckel Y, Brown JJ, Senthilkumar T, Fahrenbach AC 2024 置信度 0.82
• A new motile animal with implications for the evolution of axial polarity from the Ediacaran of South Australia.
  Fossils of the Ediacara Biota preserve the oldest evidence for complex, macroscopic animals. Most are difficult to constrain phylogenetically, however, the presence of rare, derived groups suggests that many more fossils from this period represent extant group…
  pubmed Evans SD, Hughes IV, Hughes EB, Dzaugis PW 等 2024 Nov 置信度 0.82
• The eukaryome of modern microbialites reveals distinct colonization across aquatic ecosystems.
  Protists are less studied for their role and diversity in ecosystems. Notably, protists have played and still play an important role in microbialites. Microbialites, or lithified microbial mats, represent the oldest evidence of fossil biofilms (~3.5 Gyr…
  pubmed Bonacolta AM, Visscher PT, Del Campo J, White Iii RA 2024 Sep 3 置信度 0.82
• Spaceflight alters host-gut microbiota interactions.
  The ISS rodent habitat has provided crucial insights into the impact of spaceflight on mammals, inducing symptoms characteristic of liver disease, insulin resistance, osteopenia, and myopathy. Although these physiological responses can involve the microbiome o…
  pubmed Gonzalez E, Lee MD, Tierney BT, Lytell N 等 2024 Aug 29 置信度 0.82
• Harnessing Radicals: Advances in Self-Assembly and Molecular Machinery.
  Radicals, with their unpaired electrons, exhibit unique chemical and physical properties that have long intrigued chemists. Despite early skepticism about their stability, the discovery of persistent radicals has opened new possibilities for molecular interact…
  pubmed Lee CK, Gangadharappa C, Fahrenbach AC, Kim DJ 2024 置信度 0.82
• The Astrobiological Potential of the Uranian Moon System.
  The 2023-2032 Planetary Science and Astrobiology Decadal Survey prioritized the Uranus Orbiter and Probe (UOP) mission concept as the next priority flagship mission. The UOP concept includes scientific studies of the Uranian moon system. Although the Uranian m…
  pubmed Weber JM, Leonard EJ, Jessica M. Weber, Erin J. Leonard 2024 置信度 0.82
• A Bayesian Analysis of the Probability of the Origin of Life Per Site Conducive to Abiogenesis.
  The emergence of life from nonlife, or abiogenesis, remains a fundamental question in scientific inquiry. In this article, we investigate the probability of the origin of life (per conducive site) by leveraging insights from Earth's environments. If life origi…
  pubmed Lingam M, Nichols R, Balbi A, Manasvi Lingam 等 2024 置信度 0.82
• Investigating Polyextremophilic Bacteria in Al Wahbah Crater, Saudi Arabia: A Terrestrial Model for Life on Saturn's Moon Enceladus.
  The study of extremophilic microorganisms has sparked interest in understanding extraterrestrial microbial life. Such organisms are fundamental for investigating life forms on Saturn's icy moons, such as Enceladus, which is characterized by potentially habitab…
  pubmed Dos Santos A, Schultz J, Almeida Trapp M, Modolon F 等 2024 置信度 0.82
• Biosignature Molecules Accumulate and Persist in Evaporitic Brines: Implications for Planetary Exploration.
  The abundance of potentially habitable hypersaline environments in our solar system compels us to understand the impacts of high-salt matrices and brine dynamics on biosignature detection efforts. We identified and quantified organic compounds in brines from S…
  pubmed Pozarycki C, Seaton KM, C Vincent E, Novak Sanders C 等 2024 置信度 0.82
• Three-stage formation of cap carbonates after Marinoan snowball glaciation consistent with depositional timescales and geochemistry.
  At least two global "Snowball Earth" glaciations occurred during the Neoproterozoic Era (1000-538.8 million years ago). Post-glacial surface environments during this time are recorded in cap carbonates: layers of limestone or dolostone that directly overlie gl…
  pubmed Thomas TB, Catling DC 2024 Aug 15 置信度 0.82
• Understanding the Role of Layered Minerals in the Emergence and Preservation of Proto-Proteins and Detection of Traces of Early Life.
  The origin of life remains one of the most profound mysteries in science. Over millennia, theories have evolved, yet the question persists: How did life emerge from inanimate matter? At its core, the study of life's origin offers insights into our place in the…
  pubmed Stewart SV, Erastova V 2024 置信度 0.82
• Supercritical CO(2) and Subcritical H(2)O Analysis Instrument: Automated Lipid Analysis for In Situ Planetary Life Detection.
  The search for extraterrestrial extant or extinct life in our Solar System will require highly capable instrumentation and methods for detecting low concentrations of biosignatures. This paper introduces the Supercritical CO 2 and Subcritical H 2 O Analysis (S…
  pubmed Abrahamsson V, Henderson BL, Friedman A, Gross J 等 2024 置信度 0.82
• Potential incompatibility of inherited behavior patterns with civilization: Implications for Fermi paradox.
  All intelligent organisms presumably originally have a number of inherited behavior patterns (IBPs) that are not fine-tuned for conditions prevailing in civilized communities. Indeed, some IBPs may be highly incompatible with such conditions and have high pote…
  pubmed Vinn O 2024 置信度 0.82
• A preliminary survey of the cellular responses of the black fungus Cryomyces antarcticus to long and short-term dehydration.
  The McMurdo Dry Valleys in Southern Victoria Land, Antarctica, are known for their extreme aridity, cold, and nutrient-poor conditions. These valleys provide a valuable comparison to environments on Mars. The survival of microorganisms in these areas hinges on…
  pubmed Alessia C, Federica A, Claudia P, Barbara C 等 2024 置信度 0.82
• Measuring Vesicle Loading with Holographic Microscopy and Bulk Light Scattering.
  We report efforts to quantify the loading of cell-sized lipid vesicles using in-line digital holographic microscopy. This method does not require fluorescent reporters, fluorescent tracers, or radioactive tracers. A single-color LED light source takes the plac…
  pubmed Tran LHA, Lowe LA, Deckel Y, Turner M 等 2024 Jul 24 置信度 0.82
• Can Chirality Answer Whether We Are Alone?
  Detecting biosignatures of life in extraterrestrial environments remains one of the primary objectives of scientific inquiry. Currently, both remote and direct detection methods are primarily aimed at identifying key molecular classes fundamental to terrestria…
  pubmed Bagdžiūnas G 2024 置信度 0.82
• Genes for the Type-I Reaction Center and Galactolipid Synthesis are Required for Chlorophyll a Accumulation in a Purple Photosynthetic Bacterium.
  Anoxygenic photosynthesis is diversified into two classes: chlorophototrophy based on a bacterial type-I or type-II reaction center (RC). Whereas the type-I RC contains both bacteriochlorophyll and chlorophyll, type-II RC-based phototrophy relies only on bacte…
  pubmed Tsukatani Y, Azai C, Noji T, Kawai S 等 2025 置信度 0.82
• Globally distributed bacteriophage genomes reveal mechanisms of tripartite phage-bacteria-coral interactions.
  Reef-building corals depend on an intricate community of microorganisms for functioning and resilience. The infection of coral-associated bacteria by bacteriophages can modify bacterial ecological interactions, yet very little is known about phage functions in…
  pubmed Wallace BA, Varona NS, Hesketh-Best PJ, Stiffler AK 等 2024 Jan 8 置信度 0.82
• The Unfinished Reconstructed Nature of the Last Universal Common Ancestor.
  The ultimate consequence of Darwin's theory of common descent implies that all life on earth descends ultimately from a common ancestor. Biochemistry and molecular biology now provide sufficient evidence of shared ancestry of all extant life forms. However, th…
  pubmed Delaye L 2024 Oct 置信度 0.82
• The astrochemical evolutionary traits of phospholipid membrane homochirality.
  Compartmentalization is crucial for the evolution of life. Present-day phospholipid membranes exhibit a high level of complexity and species-dependent homochirality, the so-called lipid divide. It is possible that less stable, yet more dynamic systems, promoti…
  pubmed Bocková J, Jones NC, Hoffmann SV, Meinert C 2024 置信度 0.82
• Life Detection on Icy Moons Using Flow Cytometry and Intrinsically Fluorescent Biomolecules.
  In a previous experiment, we demonstrated the capability of flow cytometry as a potential life detection technology for icy moons using exogenous fluorescent stains (Wallace et al., 2023 ). In this companion experiment, we demonstrated the capability of flow c…
  pubmed Wallace ML, Tallarida N, Schubert WW, Lambert J 等 2024 置信度 0.82
• Radiolytic Effects on Biological and Abiotic Amino Acids in Shallow Subsurface Ices on Europa and Enceladus.
  Europa and Enceladus are key targets to search for evidence of life in our solar system. However, the surface and shallow subsurface of both airless icy moons are constantly bombarded by ionizing radiation that could degrade chemical biosignatures. Therefore, …
  pubmed Pavlov AA, McLain H, Glavin DP, Elsila JE 等 2024 置信度 0.82
• Deletion of the polyketide synthase-encoding gene pks1 prevents melanization in the extremophilic fungus Cryomyces antarcticus.
  Cryomyces antarcticus, a melanized cryptoendolithic fungus endemic to Antarctica, can tolerate environmental conditions as severe as those in space. Particularly, its ability to withstand ionizing radiation has been attributed to the presence of thick and high…
  pubmed Catanzaro I, Gerrits R, Feldmann I, Gorbushina AA 等 2024 Dec 置信度 0.82
• Unveiling Challenging Microbial Fossil Biosignatures from Rio Tinto with Micro-to-Nanoscale Chemical and Ultrastructural Imaging.
  Understanding the nature and preservation of microbial traces in extreme environments is crucial for reconstructing Earth's early biosphere and for the search for life on other planets or moons. At Rio Tinto, southwestern Spain, ferric oxide and sulfate deposi…
  pubmed Maldanis L, Fernandez-Remolar D, Lemelle L, Knoll AH 等 2024 置信度 0.82
• Pyritic stromatolites from the Paleoarchean Dresser Formation, Pilbara Craton: Resolving biogenicity and hydrothermally influenced ecosystem dynamics.
  This study investigates the paleobiological significance of pyritic stromatolites from the 3.48 billion-year-old Dresser Formation, Pilbara Craton. By combining paleoenvironmental analyses with observations from well-preserved stromatolites in newly obtained d…
  pubmed Baumgartner RJ, Van Kranendonk MJ, Caruso S, Campbell KA 等 2024 置信度 0.82
• Variable and Large Losses of Diagnostic Biomarkers After Simulated Cosmic Radiation Exposure in Clay- and Carbonate-Rich Mars Analog Samples.
  Mars has been exposed to ionizing radiation for several billion years, and as part of the search for life on the Red Planet, it is crucial to understand the impact of radiation on biosignature preservation. Several NASA and ESA missions are looking for evidenc…
  pubmed Roussel A, McAdam AC, Pavlov AA, Knudson CA 等 2024 置信度 0.82
• The Preservation and Spectral Detection of Historic Museum Specimen Microbial Mat Biosignatures Within Martian Dust: Lessons Learned for Mars Exploration and Sample Return.
  The key building blocks for life on Mars could be preserved within potentially habitable paleo-depositional settings with their detection possible by utilizing mid-infrared spectroscopy; however, a definite identification and confirmation of organic or even bi…
  pubmed Preston LJ, Jungblut AD, Montgomery W, Ballard CJ 等 2024 置信度 0.82
• Cosmos MIND and matter: Is mind in spacetime?
  We attempt in this article to formulate a conceptual and testable framework weaving Cosmos, Mind and Matter into a whole. We build on three recent discoveries, each requiring more evidence: i. The particles of the Standard Model, SU(3) x SU(2) x U(1), are form…
  pubmed Kauffman S, Patra S 2024 Sep 置信度 0.82
• Self-Replication Without Hydrogen-Bonds: An Exobiotic Design.
  Life on Earth uses DNA as the central template for self-replication, genetic encoding, and information transfer. However, there are no physical laws precluding life's existence elsewhere in space, and alternative life forms may not need DNA. In the search for …
  pubmed Ams MR, McAuliffe JR, Semenick RS, Zeller M 2024 置信度 0.82
• Mars' Atmosphere as a Threshold System: Atmospheric Inventory, Escape-Energy Marginality, and a Conditional Moon–Ring Mechanics Branch
  Ancient Mars preserves evidence for episodic liquid water, valley networks, hydrothermal alteration, volcanism, and surface activity, yet modern Mars is cold, dry, and thinly atmosphered. This working draft frames Mars’ atmospheric evolution as a threshold-sys…
  datacite Caspian, Ethan 2026 置信度 0.66 Mars; atmospheric loss; early Mars climate; planetary habitability; atmospheric escape; Phobos; Deimos; Martian moons; threshold systems; terraforming; planetary science; astrobiology
• BIOLOGICAL QUARANTINE HYPOTHESIS: Earth Life as Defective Biological Substrate
  The Condom Universe Model (Budinny V, 2026) proposed that the observable universe boundary functions as a containment membrane analogous to a cyclic cosmological structure. This paper extends that framework with a biological quarantine layer. Earth biological …
  datacite V, Budinny 2026 置信度 0.66 biological quarantine hypothesiscondom universe modelnitrogen deficiencyearth lifefermi paradox
• BIOLOGICAL QUARANTINE HYPOTHESIS: Earth Life as Defective Biological Substrate
  The hypothesis proposes that the observable universe boundary functions as a containment membrane analogous to a cyclic cosmological structure. This paper extends that framework with a biological quarantine layer. Earth biological life is examined as a defecti…
  datacite V, Budinny 2026 置信度 0.66 biological quarantine hypothesiscondom universe modelnitrogen deficiencyearth lifefermi paradox
• BIOLOGICAL QUARANTINE HYPOTHESIS: Earth Life as Defective Biological Substrate
  The hypothesis proposes that the observable universe boundary functions as a containment membrane analogous to a cyclic cosmological structure. This paper extends that framework with a biological quarantine layer. Earth biological life is examined as a defecti…
  datacite V, Budinny 2026 置信度 0.66 biological quarantine hypothesiscondom universe modelnitrogen deficiencyearth lifefermi paradox