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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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Abstract Background Prostate cancer (PCa) exhibits significant ancestry-related disparity. While men of African ancestry experience higher overall mortality rates, this difference is most pronounced in Sub-Saharan Africa and for grade group 1 (GG1) disease, al…
preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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Whether and how genetic regulation of DNA methylation (DNAm) change across the lifespan remains unclear. Here, we map age-dependent methylation quantitative trait loci (longitudinal mQTLs) using linear mixed models applied to repeated blood DNAm measures from …
preprints
2026
置信度 0.74
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preprints
2026
置信度 0.74
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Proteogenomic studies have transformed the way we derive novel insights into human biology and pathophysiology but are currently limited by their proteomic coverage and ancestral representation. Here, we integrate rare and common genetic variation with measure…
preprints
2026
置信度 0.74
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Abstract Background Antimicrobial resistance (AMR) remains a major global health threat, driven by antibiotic use across human, animal, and environmental sectors. In Uganda, despite a National Action Plan and sector‑specific policies, inappropriate antibiotic …
preprints
2026
置信度 0.74
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The expansion of short tandem repeats is a feature of over 60 different human diseases. Ongoing somatic instability throughout a patient’s lifetime can influence disease progression and has emerged as a therapeutic target. Understanding its mechanism is essent…
preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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Cancer genomics research in Nigeria is growing, but the scope, methodological characteristics, geographic distribution, and translational relevance of the available evidence have not been comprehensively mapped. This scoping review will map and characterise ca…
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<i>Objective:</i> My aim was to examine the ethical, social and legal implications of pharmacogenomics. <i>Method:</i> I performed a critical review of the literature. The primary focal point is the bioethical principle discussed. The s…
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Abstract In this review we provide a brief guide to some of the resources and databases that can be used to locate information and aid research in the growing field of structural genomics. The review will provide examples, for less experienced users, of what c…
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In the past decade, various genomes have been sequenced in both plants and animals. The falling cost of genome sequencing manifests a great impact on the research community with respect to annotation of genomes. Genome annotation helps in understanding the bio…
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Abstract The tumour in the brain is a glial cell origin. Tumour factors govern cell fate during development. The murine PAX family control the transcription of embryonic cell lineages and contribute an immense role during development. PAX1-PAX9 genes assist in…
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Abstract The immunologic theorem is a subject of self also non-self differentiation directly combat infections and maintains the energy of self-antigens. Immune privilege of T-cells is prevailing via crucial and superficial prospect. The T-cell promotes the fu…
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Abstract Catfish is one of the lower teleosts whose genome research is important for evolutionary genomics. As the major aquaculture species in the USA, its genome research also has practical and economical implications. Much progress has been made in recent y…
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Abstract The encoded SOX13 gene from the HMG-box genes family is testis associated with the HMG-box domain bound with DNA. The HMG-box associated genes play a dominant role during the growth. Precisely, SOX13 is an insulin-dependent gene located on chromosome …
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Advances in genetics and genomics have transformed healthcare, requiring nurses to competently integrate genetic information into clinical practice. However, global evidence on nurses' knowledge, attitudes, and practices (KAP) remains fragmented.
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Machine learning (ML) is transforming cancer research and care by enabling analysis of complex, high-dimensional datasets spanning genomics, transcriptomics, proteomics, imaging, and clinical records. By improving risk stratification, accelerating detection an…
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