基因技术工具 · 全部实体（第 39 / 100 页）

本页收录第 3801–3900 条，共 10000 条 · 返回 基因技术工具 首页

• Low-Coverage Whole-Genome Resequencing in Livestock and Poultry: Statistical Foundations, Applications and Future Directions.
  europepmc 2026 置信度 0.80
• AI-based multimodal integration of genomics and electronic health records.
  europepmc 2026 置信度 0.80
• 25 Years Since the First Microsporidian Genome Assembly, Insights on How Genomics Has Shaped Our Understanding of Parasites with the Smallest Eukaryotic Genomes.
  Microsporidia are fungal intracellular parasites of animals and are a threat to human health and food security. In 2001, they became the first eukaryotic parasites to have their genome fully sequenced. Analysis revealed they possessed the smallest eukaryotic g…
  pubmed Shreenidhi PM, Reinke AW 2026 置信度 0.82
• Regulation of root-to-shoot ratio in plant resource allocation by external and internal cues.
  europepmc Qing Li, Yi Tong, Hongning Tong 2026 置信度 0.80
• Genomics and Multi-Omics to Guide Clinical Management in Thyroid Cancer.
  europepmc 2026 置信度 0.80
• Beyond radiogenomics: advancing imaging integration and multi-omics horizons in cancer precision medicine.
  europepmc 2026 置信度 0.80
• Genomics assisted breeding for mildew resistance in cucumber: from gene discovery to future innovations.
  europepmc 2026 置信度 0.80
• Attention deficit hyperactivity disorder (ADHD) and premature mortality: A narrative review of the literature.
  europepmc 2026 置信度 0.80
• Current landscape of Cys-OxiPTMs in plants: from hormone signaling to phenotypic control and their potential in sustainable agriculture.
  europepmc 2026 置信度 0.80
• Harnessing genomics and transcriptomics to explore the genetic and molecular basis of abiotic stress tolerance in minor millets - a comprehensive review.
  europepmc 2026 置信度 0.80
• Transforming Life Science Through Chromosome-Level Genome Assemblies.
  Advances in long-read sequencing and Hi-C scaffolding have made chromosome-level genome assembly increasingly accessible to individual laboratories, shifting genome research from large consortium-led projects toward investigator-driven studies across diverse t…
  pubmed Kon T, Kataoka K, Luo YJ, Wibisana JN 等 2026 置信度 0.82
• Genomic language models (gLMs): Emerging applications, challenges, and future directions in computational genomics.
  europepmc 2026 置信度 0.80
• Functional Genomics of Sulfur Metabolism in Rice: Insights From Transgenic and MicroRNA-Based Strategies.
  europepmc 2026 置信度 0.80
• The genomic alchemist's arsenal: A comprehensive review of gene recruitment, regulatory rewiring, and the evolutionary arms race in snake envenomation.
  Snake venom represents a striking example of evolutionary innovation, in which ancestral physiological gene networks have been co-opted into potent biochemical weapons. Advances in multi-omics, single-cell genomics, and structural bioinformatics have catalyzed…
  pubmed Ajeh IJ, Ikukpla'si OSI 2026 置信度 0.82
• Incomplete penetrance in neurogenetic disorders: current insights and emerging perspectives.
  europepmc Jiao-Jiao Xu, Dian-Fu Chen, Zhi-Ying Wu 2026 置信度 0.80
• Patient-Derived Organoid-Based CRISPR Screens in Cancer Research: Applications, Advances, and Challenges.
  europepmc 2026 置信度 0.80
• Social genomics and cancer - untangling nature from nurture in squamous cell carcinoma outcomes.
  europepmc 2026 置信度 0.80
• Recent advances in the chemical synthesis of Glycosaminoglycans.
  europepmc 2026 置信度 0.80
• Correction: Genomics of Primary and Metastatic Cutaneous Melanoma: A Systematic Review and Meta-Analysis.
  pubmed Hoang MD, Bui TO, Dao VT, Le VQ 等 2026 置信度 0.82
• Toward generalizable and interpretable AI in regulatory genomics.
  europepmc 2026 置信度 0.80
• Molecular clusters and precision medicine in pheochromocytomas and paragangliomas.
  Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors derived from chromaffin cells of the adrenal medulla and extra-adrenal paraganglia. Over the past two decades, the genomic characterization of PPGLs has profoundly transformed their di…
  pubmed Almeida MQ, Dahia PLM, Robledo M 2026 置信度 0.82
• Pharmacogenomics in Dentistry: From CYP-Mediated Drug Response to Precision Prescribing in Oral Healthcare.
  This narrative review critically assesses the clinical relevance of pharmacogenomics within dental genomics, distinguishing clinically actionable applications from emerging or investigational findings.
  pubmed Pieretto G, Cusato J, Sansavini M, Bacci C 2026 置信度 0.82
• Responsible Use of Large Language Models in Microbial Genomics and Bioinformatics: A Life-Science Framework for Reliability, Reproducibility, and Risk-Aware Interpretation.
  europepmc 2026 置信度 0.80
• Human Sex Chromosome Biology in the Genomic Era.
  europepmc 2026 置信度 0.80
• Patient-derived organoids in functional precision oncology: from experimental models to clinical decision-making.
  europepmc 2026 置信度 0.80
• Genetic services in Pakistan: a review highlighting limitations and opportunities for improvement.
  europepmc 2026 置信度 0.80
• Inherited Disorders and Disease-Resistance Genomics in Kazakhstan Ruminants: Evidence, Limits and Breeding Priorities.
  europepmc 2026 置信度 0.80
• Decoding the Mystery of Sugarcane Genome-Based Breeding: Current Advancements, Strategies, and Future Challenges.
  Sugarcane serves as one of the world's most crucial economic crops, with fundamental importance to global sugar production and the sustainable biofuel industry. To meet the rising global demands and tackle various biotic and abiotic stresses, there is an urgen…
  europepmc 2026 置信度 0.80
• From molecules to minds: Integrative multi-omics in psychiatry.
  europepmc 2026 置信度 0.80
• Harnessing plant microbiomes to enhance crop resilience and restore war-affected soils in Ukraine.
  europepmc 2026 置信度 0.80
• Variant Curation and Classification in Rare Disease Genomics: Standards and Emerging Tools for Single-Nucleotide Variant Analysis.
  europepmc 2026 置信度 0.80
• Chemogenomic sets: valuable tools for early-stage drug discovery.
  europepmc 2026 置信度 0.80
• Community Engagement in Genomic Research: Where We Have Been and Where We Should Go.
  europepmc 2026 置信度 0.80
• Artificial intelligence-driven multi-omics integration for plant enhancement: advances, challenges, and future perspectives.
  europepmc Yashi, Narendra Kumar, Rajeev Kumar, Ravi Kant Singh 2026 置信度 0.80
• Climate change-driven competition between C<sub>4</sub> weeds and crops: Ecological mechanisms, evolution and management strategies.
  europepmc 2026 置信度 0.80
• Scoping review of Australian prioritisation frameworks impacting consumer access to clinical genetics: protocol.
  Timely access to care is critical, yet prolonged waiting lists across healthcare systems cause avoidable harm and inequity, visible to clinicians who experience moral distress when patients wait unsafely. While equity is embedded in policy, performance metrics…
  pubmed Cormack M, Pinn M, Vizheh M, Long JC 等 2026 置信度 0.82
• Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review).
  europepmc 2026 置信度 0.80
• Pharmacogenomics in the Americas: the impact of genetic admixture.
  europepmc 2006 置信度 0.80
• Experimental and Computational Approaches to Identify Noncoding Pathogenic Variation in Rare Disease.
  europepmc 2026 置信度 0.80
• Genetic analysis of imaging-derived phenotypes.
  europepmc 2026 置信度 0.80
• B chromosomes put the 'super' in supernumerary.
  europepmc 2026 置信度 0.80
• Confound-aware lncRNA genomics: Separating biology from abundance, composition, and temporal artefacts.
  Long non-coding RNAs (lncRNAs) are nominated at scale as disease biomarkers and as targets for antisense and RNA-targeting therapeutics, yet many fail to replicate - a translational liability: an artefactual target wastes preclinical investment. The reflex exp…
  pubmed Tani H 2026 置信度 0.82
• AI in Genomics: From Variant Calling to Multi-Omics Integration.
  europepmc 2026 置信度 0.80
• Bispecific Antibodies in Cancer Immunotherapy: Mechanisms, Challenges, and Emerging Therapeutic Strategies.
  europepmc 2026 置信度 0.80
• Generative AI and Language Models in Human Genetics and Health: From Variant Interpretation to Clinical Decision Support.
  europepmc 2026 置信度 0.80
• Common Principles Underlie Mitochondrial DNA Heteroplasmy Dynamics in the Germline and Soma.
  europepmc 2026 置信度 0.80
• Revisiting Founder Populations in an Age of Global Biobanks.
  europepmc 2026 置信度 0.80
• Current Perspectives on <i>Mycobacterium avium</i> Complex: Taxonomy, Epidemiology, Resistance and Genomics.
  europepmc 2026 置信度 0.80
• Genetic and Molecular Basis of Cleft Lip and Palate: A Comprehensive Review.
  europepmc 2026 置信度 0.80
• Causal variants in animal genomes: approaches to identification, phenotypic impact, and implications for selective breeding.
  europepmc Viktor Balatsky, Artem Saienko, Mykyta Peka 2026 置信度 0.80
• Toward a model of repeat-driven chromosomal fragility in Triticeae: an integrated structural omics perspective.
  Abstract Background Repetitive DNA dominates cereals genomes and plays a major yet poorly understood role in shaping structural genome variation. Recent advances in long-read sequencing, pangenomics, and 3D chromatin mapping have revealed that chromosomal rear…
  europepmc Michał T. Kwiatek 2026 置信度 0.80
• Individualized antisense oligonucleotide treatment eligibility of patients living with neurodevelopmental diseases.
  europepmc 2026 置信度 0.80
• Mapping pathogen genomics training provision: a structured analysis within a global consortium network.
  europepmc 2026 置信度 0.80
• Genetic and systems-level regulation of cancer metabolism: From metabolic reprogramming to AI-driven precision oncology.
  europepmc 2026 置信度 0.80
• National genomic projects in Asia and Africa: a review.
  europepmc Aisha Hanaya Alsuwaidi, Mira Mousa, Michael Olbrich, Nour Al Dain Marzouka 等 2026 置信度 0.80
• Genomic insights into endometriosis, adenomyosis, and uterine fibroids for the clinician.
  europepmc 2026 置信度 0.80
• Advancing One Health genomics in Africa: opportunities and challenges for outbreak and antimicrobial resistance control.
  europepmc 2026 置信度 0.80
• Using user-centered design to better understand challenges faced during genetic analyses by novice genomic researchers.
  europepmc 2026 置信度 0.80
• Bioinformatics roadmap for characterizing the gut microbiome to study its interactions and associations with the gut mucosal immune system.
  europepmc 2026 置信度 0.80
• <i>Akkermansia muciniphila</i>: a member of the gut microbiota that modulates intestinal stem cell function.
  europepmc 2026 置信度 0.80
• Bridging precision agriculture and human medicine through comparative genetics.
  Comparative genetics aims to resolve the genetic and molecular architecture of complex traits and the evolutionary constraints governing biology. Recent improvements in genome assembly, coupled with population-scale multi-omics, have generated high-resolution …
  europepmc 2026 置信度 0.80
• From Variant Interpretation to Biomarker Translation: Multi-omics Integration in Inherited Neuromuscular Diseases.
  europepmc 2026 置信度 0.80
• Genetic architecture of patients with autism spectrum disorder - data analysis based on the literature review.
  europepmc Gabriela Ręka, Katarzyna Wojciechowska, Monika Lejman 2026 置信度 0.80
• Molecular and neural mechanisms of sodium sensation.
  europepmc 2026 置信度 0.80
• Precision oncology's translation gap-Can molecular tumor boards bridge it?
  europepmc 2026 置信度 0.80
• Rethinking soil-transmitted helminth diagnostics in the genomic era: Does genetic variation matter?
  europepmc 2026 置信度 0.80
• Prevalence of CYP2C19 phenotypes in patients undergoing a hiatal hernia repair.
  europepmc 2026 置信度 0.80
• ExposoGenomics: integrating genome and exposome as jointly dynamic systems for causal discovery and precision health.
  europepmc 2026 置信度 0.80
• Prenatal diagnosis and estimated penetrance of 15q11.2 BP1-BP2 microdeletion syndrome in a Chinese cohort: a retrospective study and literature review.
  europepmc 2026 置信度 0.80
• Signals Alongside Scans: A Genomics-Guided Framework for Liquid Biopsy in Bone and Soft-Tissue Sarcomas.
  europepmc 2026 置信度 0.80
• Beyond TADs and Compartments: Mesoscale Chromatin Folding and Its Dynamics in Transcriptional Regulation.
  europepmc 2026 置信度 0.80
• Genetic and epigenetic determinants of cytochrome P450 activity in psychopharmacology: from pharmacogenetics to functional pharmacogenomics.
  Classical pharmacogenetics has explained interindividual variability in psychotropic drug response primarily through inherited polymorphisms in cytochrome P450 enzymes. This framework successfully identified extreme metabolizer phenotypes and informed genotype…
  pubmed Laureano-Rivera M, de Jesús Reyes-García A, Minauro-Sanmiguel F, Vargas-Pérez H 等 2026 置信度 0.82
• Toward 3-D genome visualization with in situ cryo-electron tomography.
  europepmc 2026 置信度 0.80
• Centralized processing of frozen tumor tissues for global cancer genomics.
  Here we present the pathology workflow of the Mutographs project, a 7-year, multicancer genomics initiative led by the Sanger Institute and funded by Cancer Research UK. Mutographs aims to elucidate global differences in cancer incidence through whole-genome s…
  pubmed Abedi-Ardekani B, Nikmanesh A, Sotoudeh M, Gaborieau V 等 2026 置信度 0.82
• Ancient pathogen genomics in Africa: Current evidence and future directions.
  europepmc 2026 置信度 0.80
• Focus on DnaJ protein research from Arabidopsis to crop improvement.
  DnaJ proteins (Hsp40s) are essential components of the cellular proteostasis network, functioning as molecular co-chaperones that regulate protein folding, stability, and stress-responsive homeostasis in plants. Beyond their classical role as Hsp70 partners, a…
  pubmed Arif M, Rehman HM, Bashir S, Mahmood N 等 2026 置信度 0.82
• Genomics-driven risk assessment of antimicrobial resistance: Current status, challenges, and future perspectives.
  europepmc 2026 置信度 0.80
• Unraveling the complexity of the oilseed rape genome: from sequencing to gene discovery for trait improvement.
  Oilseed rape (Brassica napus) serves as a cornerstone of global vegetable oil production, yet its genetic improvement has historically been impeded by a complex allopolyploid genome. This review synthesizes the transformative evolution of rapeseed genomics, tr…
  europepmc 2026 置信度 0.80
• Genome assemblies and annotations are not static and need support for tracking their evolution.
  europepmc 2026 置信度 0.80
• Precision Endodontics-Advancing Towards Omics-Guided Personalisation: A Narrative Review.
  europepmc 2026 置信度 0.80
• Familial lymphoma and genetic predisposition: an updated review.
  Abstract Background Several factors contribute to the development of malignant lymphomas including environmental exposures, bacterial and viral infections, as well as familial and genetic factors. Main body Numerous somatic variants are involved in lymphomagen…
  europepmc Laura Braun, Rossella Graffeo, Kalaruban Kapilan, Harpreet Kaur Mandhair 等 2026 置信度 0.80
• Single-cell Omics Assessment of Mitochondrial Function: Current Status and Future Perspectives.
  europepmc 2026 置信度 0.80
• Trust, mistrust, and the promise of AI in genomics for African populations.
  europepmc 2026 置信度 0.80
• Investigation of pain research in Nepal since update of Health Research Priority Areas: A scoping review.
  europepmc 2026 置信度 0.80
• Unraveling Non-B DNA Structures in the Era of Telomere-to-Telomere Genomes.
  europepmc 2026 置信度 0.80
• Genetics and genomics of hybridization.
  europepmc 2026 置信度 0.80
• Identification of a novel pathogenic variant in MYLK in an Iranian family with non-syndromic familial aortic aneurysm and dissection by whole-exome sequencing and literature review.
  europepmc 2026 置信度 0.80
• The Need for Omics Studies in Chronic Kidney Disease of Unknown Etiology (CKDu): A Narrative Review and Perspective.
  europepmc 2026 置信度 0.80
• How Studying Rare Disease Leads to Mechanistic Insights and Therapeutic Development: Lessons from Nonmammalian Models.
  europepmc 2026 置信度 0.80
• Genomic, transcriptomic, and molecular predictors of response to neoadjuvant therapy in locally advanced rectal cancer: a narrative review.
  europepmc 2026 置信度 0.80
• Emerging molecular targets in gynaecologic cancers: clinical implications for personalized therapy.
  europepmc 2026 置信度 0.80
• The gene revisited: historical foundations and postgenomic complexity.
  europepmc 2026 置信度 0.80
• Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes.
  europepmc 2026 置信度 0.80
• A genome assembly of the North American golden eagle, Aquila chrysaetos canadensis.
  europepmc 2026 置信度 0.80
• Finasteride, pharmacogenomics, and suicide risk: a public health concern.
  europepmc 2026 置信度 0.80
• Editorial: Exploring the intersection of animal breeding, genetics, and genomics in modern agriculture.
  europepmc 2026 置信度 0.80
• Computational strategies for copy number variation detection, disease association, and beyond.
  europepmc 2026 置信度 0.80
• Lipid metabolism in the aphid-Buchnera symbiosis: an underexplored dimension of insect physiology.
  europepmc 2026 置信度 0.80
• Editorial: Insights in livestock genomics.
  europepmc 2026 置信度 0.80
• Harvesting insights from recent advances in yeast genomics for predictable and precision wine fermentation.
  europepmc 2026 置信度 0.80