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Objective: To analyze the clinical characteristics of breast cancer susceptibility gene ( BRCA ) germline mutation carriers with ovarian cancer, collect family history information, screen for potential BRCA mutation carriers among family members, and provide p…
pubmed
Chen MY, Zhou JL, Zhang XY, Zhai QZ 等
2026 Jul 23
置信度 0.82
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Cattle rely on the microorganisms in their rumen to break down plant matter into useable nutrients. Studies have demonstrated that the rumen microbiome plays a critical role in economically important traits. One factor that impacts rumen microbial community as…
pubmed
Lakamp AD, Adams S, Kuehn LA, Snelling WM 等
2026 Jan 8
置信度 0.82
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This study aimed to elucidate the biological mechanisms underlying the therapeutic effects of targeted alpha therapy (TAT) using a novel 211 At-labeled single-domain antibody drug ([ 211 At]At-AuNP-sdAb). By integrating transcriptomic and metabolomic analyses,…
pubmed
Zhang J, Song Z, Chen Z, Luan X 等
2026 Jul 20
置信度 0.82
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crossref
Lori A.S. Snyder
2024-03-05T15:01:45Z
置信度 0.70
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crossref
2024-02-27T13:57:51Z
置信度 0.70
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crossref
Aradhana Dohroo
2024-07-17T10:48:06Z
置信度 0.70
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crossref
2024-08-19T09:32:55Z
置信度 0.70
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crossref
2024-09-06T01:23:07Z
置信度 0.70
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Abhishek Bohra, Mukesh Choudhary, Dion Bennett, Rohit Joshi 等
2024-11-13T09:02:20Z
置信度 0.70
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crossref
Gohki Naozuka, Makoto Kawamukai, Yasuhiro Matsuo
2024-04-10T15:02:00Z
置信度 0.70
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crossref
2024-08-19T09:32:55Z
置信度 0.70
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Abstract Genetic variability is essential for the development of new crop varieties with economically beneficial traits. The traits can be inherited from wild relatives or induced through mutagenesis. Novel genetic elements can then be identified and new gene …
crossref
Surender Kumar, Anupama Singh, Chander Mohan Singh Bist, Munish Sharma
2024-04-29T01:50:25Z
置信度 0.70
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crossref
Rishi R. Burlakoti, Sanjib Sapkota, Mark Lubberts
2024-05-08T07:22:01Z
置信度 0.70
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ABSTRACT Mitochondria are essential cellular organelles that play critical roles in hematological disorders. Recurrent mutations in mitochondrial DNA (mtDNA) have been identified in patients with myelodysplastic syndromes (MDS) and serve as significant prognos…
crossref
Jing Dong, Michael T. Zimmermann, Neshatul Haque, Shahram Arsang-Jang 等
2024-09-09T00:26:02Z
置信度 0.70
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crossref
TAMMY DOELKER, JULIA GALLWAS, CARSTEN GRÜNDKER
2024-10-28T12:45:12Z
置信度 0.70
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crossref
Guo Wang, Chunmei Zong, Yuxin Qi, Guohong Sun 等
2024-10-25T04:30:30Z
置信度 0.70
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crossref
Virginia L. Corson, Antonie D. Kline
2024-01-18T17:49:06Z
置信度 0.70
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crossref
Rosanna Weksberg, Cheryl Cytrynbaum
2024-01-21T10:09:44Z
置信度 0.70
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R-spondin 1 (RSPO1), which encodes a secretory-activating protein, is a promising therapeutic target for various tumors. The aim of this study was to establish a robust RSPO1-related signature specific to esophageal cancer (ESCA). Our comprehensive study invol…
crossref
Yuansheng Lin, Xinqi Lou, Shengjun Li, Wei Cai 等
2024-05-29T15:25:19Z
置信度 0.70
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crossref
Hans Raj Mahla, Reena Rani, Khushwant B. Choudhary, Laxman Singh Rajput 等
2024-08-13T10:02:10Z
置信度 0.70
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crossref
Antonie D. Kline
2024-01-21T10:09:05Z
置信度 0.70
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crossref
Aicha Kriaa, Heykel Trabelsi
2024-07-31T01:01:40Z
置信度 0.70
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crossref
Qianqian Liang, Abin Abraham, John A. Capra, Dennis Kostka
2024-05-20T22:21:49Z
置信度 0.70
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crossref
Jiyao Liu, Caiqing Zheng, Yuange Duan
2024-04-20T05:01:25Z
置信度 0.70
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crossref
Juan C. Opazo
2024-01-15T12:45:00Z
置信度 0.70
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crossref
Mikhail Gudkov, Loïc Thibaut, Eleni Giannoulatou
2024-01-08T02:38:25Z
置信度 0.70
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crossref
Bidisha Bhowal, Yasha Hasija, Sneh L. Singla-Pareek
2024-11-26T03:32:00Z
置信度 0.70
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crossref
Katelyn R. Titus, Zoltan Simandi, Harshini Chandrashekar, Dominik Paquet 等
2024-07-10T10:39:00Z
置信度 0.70
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crossref
Bryn D. Webb, Hilary J. Vernon
2024-01-21T10:09:39Z
置信度 0.70
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crossref
George A. Diaz
2024-01-21T10:09:41Z
置信度 0.70
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crossref
Fuhong Zhang, Chenbo Shi, Qiuya He, Lu Zhu 等
2024-05-31T06:37:49Z
置信度 0.70
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crossref
Wenxiao Chen, Jinghong Hu, Jing Chen, Yuanyuan Guo 等
2024-04-27T06:22:23Z
置信度 0.70
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crossref
Vivien Narcisa Triano, Suma Shankar
2024-01-18T17:51:25Z
置信度 0.70
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crossref
2025-05-15T07:51:25Z
置信度 0.70
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Abstract Background The mechanism of mitochondria-related genes (MRGs) in childhood allergic asthma (CAS) was unclear. The aim of this study was to find new biomarkers related to MRGs in CAS. Methods This research utilized two CAS-related datasets (GSE40888 an…
crossref
Wei Zhao, Hongjuan Fang, Tao Wang, Chao Yao
2024-05-23T10:01:44Z
置信度 0.70
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Abstract Background Cyanobacteria are diverse phototrophic microbes with ecological importance and potential for biotechnology applications. One species of thermophilic cyanobacteria, Thermosynechococcus taiwanensis , has been studied for biomass pyrolysis, es…
crossref
Hsin-Ying Chang, Hsi-Ching Yen, Hsiu-An Chu, Chih-Horng Kuo
2024-08-22T18:35:21Z
置信度 0.70
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crossref
Pavel Andriyanov, Pavel Zhurilov, Alena Menshikova, Anastasia Tutrina 等
2024-10-30T13:05:23Z
置信度 0.70
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crossref
Stuart A. Scott
2024-01-18T17:52:00Z
置信度 0.70
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crossref
Qiqolei Yuan, Nengyuan Lv, Qianying Chen, Siyi Shen 等
2024-08-28T00:02:41Z
置信度 0.70
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Epigenomics assays, such as chromatin accessibility, can identify DNA-sequence-specific regulatory factors. Models that predict read counts from sequence features can explain cell-based readouts using specific DNA patterns (genomic motifs) but do not encode th…
crossref
Ignacio L. Ibarra, Johanna Schneeberger, Ege Erdogan, Lennart Redl 等
2024-08-09T03:25:45Z
置信度 0.70
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crossref
2025-05-15T07:51:25Z
置信度 0.70
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crossref
Muhammad Khuram Razzaq, Guangnan Xing, Muhammad Basit Shehzad, Ghulam Raza 等
2024-03-05T14:34:56Z
置信度 0.70
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crossref
Ambuj Kumar, Keerthana Vinod Kumar, Kavita Kundal, Avik Sengupta 等
2024-01-20T01:01:34Z
置信度 0.70
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crossref
Jonathan Dayan, Zehava Uni
2024-12-04T15:48:24Z
置信度 0.70
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The application of machine learning (ML) to genomics has transformed the process of analyzing and interpreting large-scale, complex datasets, leading to important breakthroughs in our knowledge of biological systems. This review provides a comprehensive overvi…
crossref
Saheed Adegbola Adeyanju, Taiwo Temitope Ogunjobi
2024-11-13T01:58:34Z
置信度 0.70
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Abstract Fusarium , a member of the Ascomycota fungi, encompasses several pathogenic species significant to plants and animals. Some phytopathogenic species have received special attention due to their negative economic impact on the agricultural industry arou…
crossref
Daniel A. Gomez-Chavarria, Alvaro L. Rua-Giraldo, Juan F. Alzate
2024-03-22T04:16:22Z
置信度 0.70
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crossref
Antonie D. Kline
2024-01-18T17:50:05Z
置信度 0.70
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Abstract Association between genomic variants and athletic performance has seen a high degree of controversy, as there is often conflicting data as far as the association of genomic variants with endurance, speed and strength is concerned. Here, findings from …
crossref
Aikaterini Psatha, Zeina N. Al-Mahayri, Christina Mitropoulou, George P. Patrinos
2024-05-17T13:01:41Z
置信度 0.70
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crossref
Akinori Kato
2024-02-06T10:54:33Z
置信度 0.70
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crossref
Hamza Sohail, Iqra Noor, Xuewen Xu, Rahat Sharif 等
2024-06-24T03:10:22Z
置信度 0.70
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Abstract Hepatocellular carcinoma (HCC) is one of the malignancies with the worst prognosis worldwide, in the occurrence and development of which glycolysis plays a central role. This study uncovered a mechanism by which ZNF692 regulates ALDOA-dependent glycol…
crossref
Weiwei Meng, Xiaojuan Lu, Guanglei Wang, Qingyu Xiao 等
2024-03-08T02:02:42Z
置信度 0.70
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crossref
Zhenguo Hu, Yuezhou Yao, Feiyue Chen, Luya Feng 等
2024-08-13T16:17:29Z
置信度 0.70
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crossref
Junhong Cai, Ru Wang, Yaxiong Chen, Chen Zhang 等
2023-12-03T10:36:19Z
置信度 0.70
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The genus Catenibacillus (family Lachnospiraceae , phylum Bacillota ) includes only one cultivated species so far, Catenibacillus scindens, isolated from human faeces and capable of deglycosylating dietary polyphenols and degrading flavonoid aglycones. Another…
crossref
Tobias Goris, Annett Braune
2024-05-24T07:16:59Z
置信度 0.70
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crossref
Judith G. Hall
2024-01-21T10:09:14Z
置信度 0.70
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crossref
Julie Hoover-Fong
2024-01-21T10:10:00Z
置信度 0.70
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crossref
Michele P. Lambert
2024-01-21T10:09:55Z
置信度 0.70
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crossref
George A. Diaz
2024-01-21T10:09:36Z
置信度 0.70
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crossref
Ethylin Wang Jabs
2024-01-18T17:51:15Z
置信度 0.70
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crossref
Akanksha Khare, Neha Gupta, Nidhi Srivastava, Sameer Suresh Bhagyawant
2024-08-09T01:51:45Z
置信度 0.70
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crossref
Xuenan Li, Yahui Li, Xilin Dai
2024-07-23T12:37:19Z
置信度 0.70
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Our study constitutes a pivotal advancement in elucidating the intricate relationship between the intratumoral microbiome and host gene regulation, thereby gaining insights into the pivotal role that the intratumoral microbiome plays in the etiology of gastroi…
crossref
Jing Liu, Hongyan Wang, Shuai Zhang, Jinyang Liu
2024-09-09T15:24:55Z
置信度 0.70
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crossref
Antonie D. Kline, Virginia L. Corson
2024-01-18T17:48:55Z
置信度 0.70
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Abstract: This chapter explores the transformative potential of Quantum Artificial Intelligence (Quantum AI) and precision genomics in revolutionizing cancer care and personalized medicine. Quantum AI combines the unparalleled computational power of quantum co…
crossref
Murali Krishna Pasupuleti
2024-12-01T14:54:52Z
置信度 0.70
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crossref
Clair A. Francomano
2024-01-18T17:51:10Z
置信度 0.70
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crossref
Constance L. Smith-Hicks
2024-01-21T10:10:02Z
置信度 0.70
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crossref
Stuart A. Scott
2024-01-21T10:10:23Z
置信度 0.70
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crossref
Daniel M. Ripley, Terence Garner, Adam Stevens
2024-07-03T00:43:57Z
置信度 0.70
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crossref
Randi J. Hagerman
2024-01-21T10:10:02Z
置信度 0.70
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crossref
Douglas F. Dluzen, Monika H.M. Schmidt
2024-01-18T17:53:05Z
置信度 0.70
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crossref
Melissa P. Wasserstein
2024-01-21T10:09:19Z
置信度 0.70
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crossref
Anne Slavotinek
2024-01-21T10:10:01Z
置信度 0.70
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crossref
Jaya Ganesh
2024-01-21T10:09:33Z
置信度 0.70
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ABSTRACT The relative genetic distance between populations is commonly measured using the fixation index ( F ST ). Traditionally inferred from allele frequency differences, the question arises how F ST can be estimated and interpreted when analysing genomic da…
crossref
Menno J. de Jong, Cock van Oosterhout, A. Rus Hoelzel, Axel Janke
2024-09-25T21:30:11Z
置信度 0.70
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Abstract Leeches are well known for their blood-feeding habits and are widely used for medicinal purposes as they secrete various antithrombotic substances. However, some leeches such as Whitmania spp. exhibit non-hematophagous feeding habits and their signifi…
crossref
Fang Zhao, Zuhao Huang, Lizhou Tang, Bo He 等
2024-05-10T22:25:22Z
置信度 0.70
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crossref
Leticia Rodríguez-Montes, Henrik Kaessmann
2024-06-27T14:33:16Z
置信度 0.70
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crossref
Noah Lorincz-Comi, Yihe Yang, Gen Li, Xiaofeng Zhu
2024-04-06T12:57:05Z
置信度 0.70
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crossref
Sanchita Naha, Sarvjeet Kaur, Ramcharan Bhattacharya, Srinivasulu Cheemanapalli 等
2024-10-25T06:02:29Z
置信度 0.70
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crossref
2008-05-23T10:37:37Z
置信度 0.70
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crossref
Melissa P. Wasserstein
2024-01-21T10:09:18Z
置信度 0.70
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crossref
Dhruv K. Patel, Sonja A. Rasmussen
2024-01-21T10:09:21Z
置信度 0.70
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crossref
Constance B. Hilliard
2024-06-13T07:22:54Z
置信度 0.70
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Introduction: Less than half of eligible Black women are assessed for genetic risk and only 28% engage in recommended HBOC risk-reducing interventions. CHWs are trusted members of the community that work as a liaison between health systems and the community to…
crossref
Caitlin G. Allen, Ashley Hatch, Elizabeth Hill, Suparna Qanungo 等
2024-05-31T21:00:43Z
置信度 0.70
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crossref
2025-05-15T07:51:25Z
置信度 0.70
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Abstract Background Current evidence suggests a significant association between metabolites and ovarian cancer (OC); however, the causal relationship between the two remains unclear. This study employs Mendelian randomization (MR) to investigate the causal eff…
crossref
Yedong Huang, Wenyu Lin, Xiangqin Zheng
2024-01-23T09:02:07Z
置信度 0.70
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crossref
Bruno Paiva, María-José Calasanz
2024-07-11T15:34:14Z
置信度 0.70
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crossref
Lauren E. Fries, Sumantra Chatterjee
2024-11-05T22:52:04Z
置信度 0.70
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crossref
Jorge Antonio Benitez
2024-06-26T17:12:47Z
置信度 0.70
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crossref
Rafeh Naqash
2025-06-10T12:58:18Z
置信度 0.70
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The ethical standards for the responsible conduct of human research have come a long way; however, concerns surrounding equity remain in human genetics and genomics research. Addressing these concerns will help society realize the full potential of human genom…
crossref
Ann M. Mc Cartney, Amber Hartman Scholz, Mathieu Groussin, Ciara Staunton
2024-04-12T18:40:06Z
置信度 0.70
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crossref
Peng Wang, Ye Wang, Yu Wang
2024-05-14T22:01:35Z
置信度 0.70
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crossref
2024-04-02T09:51:43Z
置信度 0.70
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crossref
Johni Debbarma, Mamta Bhattacharjee, Trishna Konwar, Channakeshavaiah Chikkaputtaiah 等
2024-03-05T19:34:56Z
置信度 0.70
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Genomic Language Models (GLMs), which learn from nucleotide sequences, are crucial for understanding biological principles and excel in tasks such as sequence generation and classification. However, state-of-the-art models vary in training methods, architectur…
crossref
Shibo Qiu
2024-11-26T20:01:49Z
置信度 0.70
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crossref
Gizachew Yilma Kebede, Temesgen Abo Eritro, Deressa Tesfaye Gutu
2024-10-23T16:02:38Z
置信度 0.70
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crossref
Hengrui Liu, Jieling Weng, Christopher L.-H. Huang, Antony P. Jackson
2024-09-19T14:02:19Z
置信度 0.70
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Abstract Global inequality rooted in legacies of colonialism and uneven development can lead to systematic biases in scientific knowledge. In ecology and evolutionary biology, findings, funding and research effort are disproportionately concentrated at high la…
crossref
Ethan B. Linck, Carlos Daniel Cadena
2024-07-13T07:30:10Z
置信度 0.70
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crossref
Sumayah I. Alsanie, Latifah A. Aljabari, Najla A. Aljabari, Samira Smajlovic 等
2024-08-02T04:16:07Z
置信度 0.70
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crossref
Pradnya Kamble, Prinsa R. Nagar, Kaushikkumar A. Bhakhar, Prabha Garg 等
2024-09-19T03:33:55Z
置信度 0.70
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Abstract Gastric cancer (GC) is one hackneyed malignancy tumor accompanied by high death rate. DKC1 has been discovered to serve as a facilitator in several cancers. Additionally, it was discovered from one study that DKC1 displayed higher expression in GC tis…
crossref
Huihua Chen, Yibo Wu, Yancheng Jiang, Zixuan Chen 等
2024-02-20T09:03:54Z
置信度 0.70