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• Global Genetic Engineering Market 2024 To 2033
  Genetic Engineering Market Size, Trends and Insights By Product (Biochemical, Genetic Markers), By Devices (PCR, Gene Gun, Gel Assemblies), By Techniques (Gene Splicing, Artificial Selection, Recombinant DNA Technology, Synthesizing DNA, Gene Editing, Other), …
  datacite Sirsat, Nitin 2024 置信度 0.66 Genetic Engineering MarketGenetic Engineering Market SizeGenetic Engineering Market ShareGenetic Engineering Market TrendsGenetic Engineering Market Report
• Automated genome editing of induced pluripotent stem cells using the CRISPR/Cas9 method
  The discovery of the CRISPR/Cas9 system in 2012 has opened up new possibilities for targeted, inexpensive, and reproducible genetic modification of human cells. One of these possibilities is the targeted modification of induced pluripotent stem cells (iPS) for…
  datacite Nießing, Bastian 2024 置信度 0.66 Hochschulschriftgenome editing , CRISPR/Cas9 , automation , StemCellFactory , induced pluripotent stem cells , iPS cells
• Building a bridge between biophysics and neurobiology: A synergic approach to develop Alzheimer’s disease translational models and research tools
  Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder, accounting for 60-70% of dementia cases diagnosed worldwide. The impact of AD is rapidly increasing, with deaths more than doubling from 2000 to 2021. As populations age, especially in …
  datacite Gonzalez Diaz, Alicia 2024 置信度 0.66 Amyloid-βiPSCOligomersPhase separationPreclinical models
• УСПЕХИ ГЕНОМНОГО РЕДАКТИРОВАНИЯ КАРТОФЕЛЯ
  Эффективность и точность подходов редактирования генома растений совершенствуются с каждым годом, благодаря чему значительно расширяются возможности улучшения различных характеристик сельскохозяйственных культур. Картофель – важнейшая овощная и техническая кул…
  datacite Дегтярёва, Влада, Долгов, Сергей, Мирошниченко, Дмитрий 2024 置信度 0.66 genome editingpotatoCRISPR/Cas9TALENгеномное редактирование
• Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system
  This repository contains extended and underlying data for "Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system". Modaffari et al., 2024.
  datacite Modaffari, Domenico 2024 置信度 0.66 Cell biologyMicrobiologyFOS: Biological sciences
• Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system
  This repository contains extended and underlying data for "Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system". Modaffari et al., 2024.
  datacite Modaffari, Domenico 2024 置信度 0.66 Cell biologyMicrobiologyFOS: Biological sciences
• Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system
  This repository contains extended and underlying data for "Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system". Modaffari et al., 2024.
  datacite Modaffari, Domenico 2024 置信度 0.66 Cell biologyMicrobiologyFOS: Biological sciences
• DeepFM-Crispr: Prediction of CRISPR On-Target Effects via Deep Learning
  Since the advent of CRISPR-Cas9, a groundbreaking gene-editing technology that enables precise genomic modifications via a short RNA guide sequence, there has been a marked increase in the accessibility and application of this technology across various fields.…
  datacite Bao, Condy, Liu, Fuxiao 2024 置信度 0.66 Quantitative Methods (q-bio.QM)Artificial Intelligence (cs.AI)Machine Learning (cs.LG)FOS: Biological sciencesFOS: Biological sciences
• JosefAlbers/Phi-3-Vision-MLX: Phi-3-MLX: Language and Vision Models for Apple Silicon
  Phi-3-MLX is a versatile AI framework that leverages both the Phi-3-Vision multimodal model and the recently updated (July 2, 2024) Phi-3-Mini-128K language model, optimized for Apple Silicon using the MLX framework. This project provides an easy-to-use interf…
  datacite JosefAlbers, Rémi 2024 置信度 0.66
• Versatile electroporation protocols enable reproducible CRISPR-RNP delivery across multiple primary mouse cells of the hematopoietic lineage
  preprints 2026 置信度 0.74
• The Genetic Revolution in Cardiometabolic Disease: A Review of Novel RNA and Gene‐Editing Therapies Targeting APOC3, ANGPTL3, and Lp(a)
  preprints 2025 置信度 0.74
• WormTagDB: A Systematic Survey of Endogenously Tagged Proteins in C. elegans and Roadmap Towards the Tagged Proteome
  preprints 2025 置信度 0.74
• Engineering quantitative root disease resistance in barley by targeting conserved SCAR susceptibility genes without compromising seed yield or mycorrhizal symbiosis
  preprints 2026 置信度 0.74
• Generating long deletions across the genome with pooled paired prime editing screens
  preprints 2025 置信度 0.74
• Sleeping ORANGE: A Transposase-Enhanced CRISPR Approach to Boost Endogenous Protein Tagging Efficiency
  preprints 2025 置信度 0.74
• Stromal Prostaglandin is a Dominant Spatial Regulator of Cell-fate Plasticity in Colorectal Cancer
  preprints 2026 置信度 0.74
• A tRNA-gRNA multiplexing system for CRISPR genome editing in <i>Marchantia polymorpha</i>
  preprints 2025 置信度 0.74
• Oxidative Stress Susceptibility, Complement Dysregulation, and Metabolic Reprogramming in CFH Y402H Patient-Derived Choriocapillaris Endothelial Cells
  Abstract Age-related macular degeneration (AMD) is a leading cause of central vision loss. Immunofluorescence and gene expression studies in human donor eyes have shown that choriocapillaris endothelial cells (CECs) are lost before retinal pigment epithelium (…
  preprints 2026 置信度 0.74
• SUBCELLULAR FUNCTIONS OF <i>UBE3A</i> ISOFORMS DRIVE SYNAPTIC DYSFUNCTION IN ANGELMAN SYNDROME
  preprints 2026 置信度 0.74
• Cutting Through the Artifacts: Dissecting gRNA Impurities with FUSS-seq
  preprints 2025 置信度 0.74
• CRISMER: A Transformer-based Interpretable Deep Learning Approach for Genome-wide CRISPR-Cas9 Off-Target Prediction and Optimization
  preprints 2025 置信度 0.74
• Gene Editing and Aging: A Bibliometric Analysis of Global Trends and Frontier Themes (2015-2024)
  Objective The accumulation of DNA damage and mutations is a key contributor to aging. Recent studies have shown that disrupting the Beclin 1-BCL2 autophagy regulatory complex through gene editing can extend lifespan in mice. The precise application of gene edi…
  preprints 2025 置信度 0.74
• Human iPSC-derived liver organoids model multicellular tissue responses and therapeutic rescue in Wolman disease
  preprints 2025 置信度 0.74
• Supercoiling twists Cas9 off-target discrimination when nicking and cleaving
  preprints 2026 置信度 0.74
• Retinal organoids mirror CRISPR/Cas9 gene editing efficiency observed in vivo
  preprints 2024 置信度 0.74
• A mechanistic free-energy model explains and predicts sequence- and context-dependent CRISPR–Cas9 activity
  preprints 2025 置信度 0.74
• Ovothiol A mediates singlet oxygen resistance and acclimation in Chlamydomonas
  preprints 2026 置信度 0.74
• Metabolite import via SLC33A1 enables ATF6 activation by endoplasmic reticulum stress
  preprints 2025 置信度 0.74
• Refined CRISPR/Cas9 genome editing in pea aphids uncovers the essential roles of <i>Laccase2</i> in overwintering egg adaptation
  preprints 2024 置信度 0.74
• A CROP-seq screen of histone modifying enzymes reveals histone demethylase Kdm5c regulates inflammatory macrophage activation
  preprints 2025 置信度 0.74
• Initiation of asexual reproduction by the AP2/ERF gene <i>GEMMIFER</i> in <i>Marchantia polymorpha</i>
  preprints 2026 置信度 0.74
• Design of Theophylline Binding Guide RNA for Allosteric Regulation of CRISPR/Cas9 System
  preprints 2024 置信度 0.74
• Optimization of CRISPR/Cas9 Gene Editing System in Sheep Oocytes via Microinjection
  preprints 2024 置信度 0.74
• A compendium of nonredundant short Polymerase III promoters for CRISPR applications
  preprints 2024 置信度 0.74
• <i>Pseudomonas putida</i> JM37 as a novel bacterial chassis for ethylene glycol upcycling
  preprints 2025 置信度 0.74
• Reciprocal interactions between EMT and BMP signalling drive collective cell invasion
  preprints 2025 置信度 0.74
• A self-limiting Sterile Insect Technique alternative for <i>Ceratitis capitata</i>
  preprints 2024 置信度 0.74
• Improved gene editing and fluorescent-protein tagging in Aspergillus nidulans using a Golden Gate-based CRISPR-Cas9 plasmid system
  preprints 2024 置信度 0.74
• Cardiac Applications of CRISPR/AAV-Mediated Precise Genome Editing
  preprints 2024 置信度 0.74
• Efficacy of CRISPR-Cas9 Gene Editing for Targeting KRAS Mutations in Pancreatic Cancer: A systematic review
  preprints 2024 置信度 0.74
• Application of CRISPR/Cas9 Technology in Rice Germplasm Innovation and Genetic Improvement
  preprints 2024 置信度 0.74
• A Key Role for <i>S-</i> Nitrosylation in Immune Regulation and Development in the Liverwort <i>Marchantia polymorpha</i>
  preprints 2025 置信度 0.74
• Efficient mutagenesis of maize inbreds using biolistics, multiplex CRISPR/Cas9 editing, and Indel-Selective PCR
  preprints 2024 置信度 0.74
• Haplotype editing with CRISPR/Cas9 as a therapeutic approach for dominant-negative missense mutations in <i>NEFL</i>
  preprints 2024 置信度 0.74
• Optimizing Genome Editing in Bovine Cells: A Comparative Study of Cas9 Variants and CRISPR Delivery Methods
  preprints 2024 置信度 0.74
• Accurate prediction of CRISPR editing outcomes in somatic cell lines and zygote with few-shot learning
  preprints 2024 置信度 0.74
• Programmable epigenome editing by transient delivery of CRISPR epigenome editor ribonucleoproteins
  preprints 2024 置信度 0.74
• EASY-CRISPR: a toolbox for high-throughput single-step custom genetic editing in bacteria
  Targeted gene editing can be achieved using CRISPR/Cas9-assisted recombineering. However, high-efficiency editing requires careful optimization for each locus to be modified which can be tedious and time-consuming. In this work, we developed a simple, fast and…
  preprints 2025 置信度 0.74
• New alleles of Arabidopsis <i>BIK1</i> reinforce its predominant role in pattern-triggered immunity and caution interpretations of other reported functions
  preprints 2025 置信度 0.74
• Successful delivery of CRISPR-Cas9 with a baculovirus vector for insect brain targets
  preprints 2024 置信度 0.74
• KOnezumi-AID: A Software to Automate the Design of Multiplex Knockouts Using Target-AID
  preprints 2024 置信度 0.74
• Facilitating Gene Editing in Human Lymphoma Cells Using Murine Ecotropic γ-Retroviruses
  preprints 2024 置信度 0.74
• Cas9-expressing cattle using all-in-one CRISPR/Cas9 for bovine genome editing
  preprints 2024 置信度 0.74
• Targeted H3K9 acetylation at lncSox1 promoter by cell type-specific epigenome editing promotes intermediate progenitor proliferation in developing mouse cortex
  preprints 2024 置信度 0.74
• Rapid degradation of 6 class I HDAC complexes reveals minimal functional overlap between complexes
  The class 1 HDACs 1, 2 and 3 form seven families of distinct large multiprotein complexes that regulate gene expression via deacetylation of lysines in histone tails. The degree of redundancy and functional overlap between complexes and their primary gene targ…
  preprints 2025 置信度 0.74
• Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation
  preprints 2024 置信度 0.74
• Coupling CRISPR Scanning with Targeted Chromatin Accessibility Profiling using a Double-Stranded DNA Deaminase
  preprints 2024 置信度 0.74
• CRISPR-CAS9 MEDIATED EDITING OF THE <i>LACZ</i> GENE FOR OPTIMIZING LIPASE PRODUCTION AND CHARACTERIZATION IN ENGINEERED <i>ESCHERICHIA COLI</i> USING POTATO PEEL AS A GLUCOSE SOURCE
  preprints 2024 置信度 0.74
• StreptoCAD: An open-source software toolbox automating genome engineering workflows in streptomycetes
  preprints 2024 置信度 0.74
• A CRISPR/ <i>Sp</i> Cas9M-reporting system for efficient and rapid genome editing in <i>Caulobacter crescentus</i>
  preprints 2024 置信度 0.74
• Pioneering Genome Editing in Parthenogenetic Stick Insects: CRISPR/Cas9-Mediated gene knockout in Medauroidea extradentata
  preprints 2024 置信度 0.74
• Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells
  preprints 2024 置信度 0.74
• Application of a GRF-GIF chimera enhances plant regeneration for genome editing in tomato
  preprints 2024 置信度 0.74
• CRISPRoff epigenetic editing for programmable gene silencing in human cells without DNA breaks
  preprints 2024 置信度 0.74
• The Advancement and Applications of Prime Editing
  Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), an exceptionally potent genome-editing technique developed in 2012, is the ideal tool of the future for treating diseases by permanently correcting deleterious base mutations or disrupting dis…
  preprints 2024 置信度 0.74
• The tryptophan-binding pockets of Arabidopsis AGO1 facilitate amplified RNA interference via SGS3
  preprints 2025 置信度 0.74
• Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach
  preprints 2025 置信度 0.74
• Disruption of the SAGA CORE triggers collateral degradation of KAT2A
  preprints 2025 置信度 0.74
• Potential CRISPR/Cas9 Gene Editing Applications in Reversing Acquired Resistance to EGFR-TKIs due to Secondary and Tertiary Mutations to EGFR in NSCLC
  preprints 2024 置信度 0.74
• <i>De novo</i> design of potent CRISPR-Cas13 inhibitors
  preprints 2024 置信度 0.74
• Awakening prime editing for precision engineering of probiotic <i>Escherichia coli</i> Nissle 1917
  preprints 2024 置信度 0.74
• Unlocking The Potential and Myth of Personalized Vaccines, CRISPR-CAS9, and Bacteriotherapy, as Therapeutic Options for Cancer
  preprints 2024 置信度 0.74
• Engineered CRISPR-Base Editors as a Permanent Treatment for Familial Dysautonomia
  preprints 2024 置信度 0.74
• CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation
  preprints 2024 置信度 0.74
• Enhanced <i>in vivo</i> gene knockout with undetectable off-targets using multiplexed Cas12a sgRNAs
  preprints 2024 置信度 0.74
• Nucleophagy removes cytotoxic trapped PARP1
  preprints 2025 置信度 0.74
• Structural basis for a dual-function type II-B CRISPR-Cas9
  preprints 2024 置信度 0.74
• Engineering Adaptive Alleles for <i>Escherichia coli</i> Growth on Sucrose Using the EasyGuide CRISPR System
  preprints 2024 置信度 0.74
• Multiplexed high-content imaging uncovers morphological diversity of lymphocyte activation and dysfunction
  preprints 2026 置信度 0.74
• Single cell variation and rapid emergence of phenotypic heterogeneity in cell lines- a cautionary tale for devotees of CRISPR-Cas9
  preprints 2024 置信度 0.74
• Hi-TARGET: A fast, efficient and versatile CRISPR type I-B genome editing tool for the thermophilic acetogen Thermoanaerobacter kivui
  preprints 2025 置信度 0.74
• Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing
  preprints 2024 置信度 0.74
• Advancements in Plant Gene Editing Technology: From Construct Design to Enhanced Transformation Efficiency
  preprints 2024 置信度 0.74
• CRISPR/Cas9 alter NFYA binding site on CD44-regulating cis-element and control CD44 expression in breast cancer cells
  preprints 2024 置信度 0.74
• Defining Mechanistic Links Between the Non-Coding Variant rs17673553 in<i>CLEC16A</i>and Lupus Susceptibility
  preprints 2024 置信度 0.74
• How Helpful May Be a CRISPR/Cas-Based System for Food Traceability?
  preprints 2024 置信度 0.74
• Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems
  preprints 2024 置信度 0.74
• PETRA: Prime editing of transcribed regulatory elements to assay expression
  preprints 2025 置信度 0.74
• CRISPR-GEM: A Novel Machine Learning Model for CRISPR Genetic Target Discovery and Evaluation
  preprints 2024 置信度 0.74
• CRISPR-Cas9/Cas12a Systems for efficient genome editing and large genomic fragment deletions in <i>Aspergillus niger</i>
  preprints 2024 置信度 0.74
• Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs
  preprints 2024 置信度 0.74
• A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440
  preprints 2024 置信度 0.74
• Gene editing tool-loaded biomimetic cationic vesicles with highly efficient bacterial internalization for in vivo eradication of pathogens
  preprints 2024 置信度 0.74
• Crackling Cloud: an event-driven, cloud-based CRISPR-Cas9 guide RNA design tool
  preprints 2024 置信度 0.74
• Enhancement of CRISPR-Cas12a System through Universal Circular RNA Design
  preprints 2024 置信度 0.74
• Emerging Strategies in Cartilage Repair and Joint Preservation
  preprints 2024 置信度 0.74
• FLP-15 functions through the GPCR NPR-3 to regulate local and global search behaviours in Caenorhabditis elegans
  preprints 2025 置信度 0.74
• Molecular engineering and dynamic activation mechanism of a PAM-flexible compact CRISPR-Cas9
  preprints 2024 置信度 0.74
• Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials
  preprints 2025 置信度 0.74
• Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in <i>Plasmodium berghei</i>
  preprints 2024 置信度 0.74