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• Multibeam bathymetry raw data (Kongsberg EM712 entire dataset) of RV MARIA S. MERIAN during cruise MSM139
  Raw multibeam bathymetry data were collected aboard RV MARIA S. Merian during cruise MSN139 using a Kongsberg EM 712 multibeam echosounder. The expedition took place during 2025-07-25 – 2025-08-27 from Reykjavik (Iceland) to Reykjavik (Iceland) in the North At…
  datacite John, Uwe, Wölfl, Anne-Cathrin 2026 置信度 0.66 BathymetryMultibeam EchosounderEvent labelBinary ObjectBinary Object (Media Type)
• Water column raw data (Kongsberg EM712 entire dataset) of RV MARIA S. MERIAN during cruise MSM139
  Raw multibeam bathymetry data were collected aboard RV MARIA S. Merian during cruise MSN139 using a Kongsberg EM 712 multibeam echosounder. The expedition took place during 2025-07-25 – 2025-08-27 from Reykjavik (Iceland) to Reykjavik (Iceland) in the North At…
  datacite John, Uwe 2026 置信度 0.66 BathymetryMultibeam EchosounderEvent labelBinary ObjectBinary Object (Media Type)
• Multibeam bathymetry raw data (Kongsberg EM 124 entire dataset) of RV MARIA S. Merian during cruise MSM139
  Raw multibeam bathymetry data were collected aboard RV MARIA S. Merian during cruise MSN139 using a Kongsberg EM 124 multibeam echosounder. The expedition took place during 2025-07-25 – 2025-08-27 from Reykjavik (Iceland) to Reykjavik (Iceland) in the North At…
  datacite John, Uwe, Wölfl, Anne-Cathrin 2026 置信度 0.66 BathymetryMultibeam EchosounderEvent labelBinary ObjectBinary Object (Media Type)
• Figures 69–94 in Genomics-Based taxonomic refinement of Emesis FaBricius (Lepidoptera: Riodinidae)
  Figures 69–94. Genitalia of Emesis (Emesis, Aphacitis, Mandania, Tenedia), detailed data in text or TaBle S1 in the supplemental file (ZhanG et al. 2025). In FiG. 69–107, lateral and ventral views are denoted By odd and even numBers, respectively (except FiG. …
  datacite Grishin, JinG ZhanG Qian ConG Jinhui Shen Leina SonG Nick V. 2025 置信度 0.66 BiodiversityTaxonomyAnimaliaArthropodaInsecta
• Figures 69–94 in Genomics-Based taxonomic refinement of Emesis FaBricius (Lepidoptera: Riodinidae)
  Figures 69–94. Genitalia of Emesis (Emesis, Aphacitis, Mandania, Tenedia), detailed data in text or TaBle S1 in the supplemental file (ZhanG et al. 2025). In FiG. 69–107, lateral and ventral views are denoted By odd and even numBers, respectively (except FiG. …
  datacite Grishin, JinG ZhanG Qian ConG Jinhui Shen Leina SonG Nick V. 2025 置信度 0.66 BiodiversityTaxonomyAnimaliaArthropodaInsecta
• NOBEL PRIZE IN SEVERAL CATEGORIES AND QUANTUM VALLEY AMARAVATI AWARD TO PRAHARSHIT SHARMAJI
  Praharshit Sharma is Sure-Shot BOTH 11 Million SEK (Swedish Kronor) NOBELprize Winner + ₹100-Crores INR AP : Andhra Pradesh CM Nara Chandra Babu Naidu's Quantum Valley Award Winner cf. https://youtu.be/iX6RkmTpj7g SUMMARY EXEMPLARY: of *SHANMUGA PRAHARSHIT SHA…
  datacite PRAHARSHIT SHARMA, KANCHINAHDHAM SHANMUGA 2026 置信度 0.66 Computational creativityComputational intelligence
• NOBEL PRIZE IN SEVERAL CATEGORIES AND QUANTUM VALLEY AMARAVATI AWARD TO PRAHARSHIT SHARMAJI
  Praharshit Sharma is Sure-Shot BOTH 11 Million SEK (Swedish Kronor) NOBELprize Winner + ₹100-Crores INR AP : Andhra Pradesh CM Nara Chandra Babu Naidu's Quantum Valley Award Winner cf. https://youtu.be/iX6RkmTpj7g SUMMARY EXEMPLARY: of *SHANMUGA PRAHARSHIT SHA…
  datacite PRAHARSHIT SHARMA, KANCHINAHDHAM SHANMUGA 2026 置信度 0.66 Computational creativityComputational intelligence
• NIH Comparative Genomics Resource (CGR) – Final Report to the NIH Scientific Data Council
  The NIH Comparative Genomics Resource (CGR) was a five-year (FY2021-2025) initiative to modernize the data and tools for comparative genomics research. Developed and managed by the National Center for Biotechnology Information (NCBI) at the National Library of…
  datacite Murphy, Terence, Ketter, Anne, Schneider, Valerie, Thibaud-Nissen, Françoise 等 2026 置信度 0.66 comparative genomics
• NIH Comparative Genomics Resource (CGR) – Final Report to the NIH Scientific Data Council
  The NIH Comparative Genomics Resource (CGR) was a five-year (FY2021-2025) initiative to modernize the data and tools for comparative genomics research. Developed and managed by the National Center for Biotechnology Information (NCBI) at the National Library of…
  datacite Murphy, Terence, Ketter, Anne, Schneider, Valerie, Thibaud-Nissen, Françoise 等 2026 置信度 0.66 comparative genomics
• Figure 11 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 11. Maximum likelihood phylogenetic tree of the three Mitosporidium species and their relatives, based on concatenated amino acid sequences. Based on the dataset by Haag et al., 2014 [46], added with the sequence of Paramicrosporidium saccamoebae and th…
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomyProtozoaMicrosporidiaMitosporidium
• Figure 11 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 11. Maximum likelihood phylogenetic tree of the three Mitosporidium species and their relatives, based on concatenated amino acid sequences. Based on the dataset by Haag et al., 2014 [46], added with the sequence of Paramicrosporidium saccamoebae and th…
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomyProtozoaMicrosporidiaMitosporidium
• Figure 6 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 6. Maximum likelihood phylogenetic tree of geoplanids, based on concatenated amino acid sequences of 12 mitochondrial proteins. *For Kontikia andersoni, ND4L, which was not found, was replaced by a blank sequence in the dataset. Subfamilies are indicate…
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomy
• Figure 6 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 6. Maximum likelihood phylogenetic tree of geoplanids, based on concatenated amino acid sequences of 12 mitochondrial proteins. *For Kontikia andersoni, ND4L, which was not found, was replaced by a blank sequence in the dataset. Subfamilies are indicate…
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomy
• Code for: Etiology-guided mutational signature learning from DNA repair knockouts in cell lines using supervised NMF
  This record contains the archived source code for the SNMF repository accompanying the accepted NAR Genomics and Bioinformatics manuscript:“Etiology-guided mutational signature learning from DNA repair knockouts in cell lines using supervised NMF” (NARGAB-2025…
  datacite Goossens, Sander, Gonçalves, Joana 2026 置信度 0.66
• Code for: Etiology-guided mutational signature learning from DNA repair knockouts in cell lines using supervised NMF
  This record contains the archived source code for the SNMF repository accompanying the accepted NAR Genomics and Bioinformatics manuscript:“Etiology-guided mutational signature learning from DNA repair knockouts in cell lines using supervised NMF” (NARGAB-2025…
  datacite Goossens, Sander, Gonçalves, Joana 2026 置信度 0.66
• Figure 8 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 8. Mitogenome of Mitosporidium sp JL472 (Mtspo_JL472) from Australoplana sanguinea. The mitogenome is 11 985 bp in length. The mitogenome could not be circularised and is represented as linear.
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomyProtozoaMicrosporidiaMitosporidium
• Figure 8 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 8. Mitogenome of Mitosporidium sp JL472 (Mtspo_JL472) from Australoplana sanguinea. The mitogenome is 11 985 bp in length. The mitogenome could not be circularised and is represented as linear.
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomyProtozoaMicrosporidiaMitosporidium
• Publication: Records Broken by N-K Universal Computer with 10³⁰⁰ Entangled N-Pairs   Complete Inventory of Computational, Scientific, and Theoretical Records Shattered By Malik Muhammad Usman Multan, Pakistan.
  Publication: Records Broken by N-K Universal Computer with 10³⁰⁰ Entangled N-Pairs Complete Inventory of Computational, Scientific, and Theoretical Records Shattered By Malik Muhammad Usman Multan, Pakistan. --- Publication Metadata Field Value Title Complete …
  datacite Usman Malik, Muhammad 2026 置信度 0.66
• Publication: Records Broken by N-K Universal Computer with 10³⁰⁰ Entangled N-Pairs   Complete Inventory of Computational, Scientific, and Theoretical Records Shattered By Malik Muhammad Usman Multan, Pakistan.
  Publication: Records Broken by N-K Universal Computer with 10³⁰⁰ Entangled N-Pairs Complete Inventory of Computational, Scientific, and Theoretical Records Shattered By Malik Muhammad Usman Multan, Pakistan. --- Publication Metadata Field Value Title Complete …
  datacite Usman Malik, Muhammad 2026 置信度 0.66
• Figure 9 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 9. Alignment, presented as a LOGO figure, of the three putative proteins orf130 from Mitosporidium Mtspo_JL467, orf138 from Mitosporidium Mtspo_JL472 and orf138 from Mitosporidium daphniae. There is a nearly entirely conserved 20-amino-acid sequence in …
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomyProtozoaMicrosporidiaMitosporidium
• Figure 9 in An Irish cocktail of flatworm, earthworm and parasite DNAs: genomics of invasive land flatworms (Geoplanidae) reveal infestations by two new Mitosporidium species (Microsporidia)
  Figure 9. Alignment, presented as a LOGO figure, of the three putative proteins orf130 from Mitosporidium Mtspo_JL467, orf138 from Mitosporidium Mtspo_JL472 and orf138 from Mitosporidium daphniae. There is a nearly entirely conserved 20-amino-acid sequence in …
  datacite Gastineau, Romain, Murchie, Archie K., Winsor, Leigh, Justine, Jean-Lou 2025 置信度 0.66 BiodiversityTaxonomyProtozoaMicrosporidiaMitosporidium
• BioRemPP Database: A Curated Compound-Centric Resource for Bioremediation Potential Profiling
  Overview The BioRemPP Database (Bioremediation Potential Profile Database) is a curated, integrated resource designed to support environmental bioremediation research by systematically linking chemical compounds, genes, KEGG Orthology groups, enzyme activities…
  datacite Lima Silva, Douglas Felipe, Fassarella Agnez-Lima, Lucymara 2026 置信度 0.66
• PREP-aring is worth it: Success of the Case Western Reserve University post-baccalaureate research education program and its scholars.
  The National Institute of General Medical Sciences (NIGMS) Post-baccalaureate Research Education Program (PREP) was a research-intense, one-year training program for recent college graduates from experiential backgrounds uncommon in science who intended to mat…
  pubmed Crawford DC, Vazquez-Hidalgo E, Lou H 2026 置信度 0.82
• Global genomic landscape of the Klebsiella oxytoca complex: diversity, resistome and plasmidome (1974-2025).
  Klebsiella oxytoca species complex (KoSC) is an opportunistic pathogen causing various infections. However, our understanding of their population structure and the co-occurrence of specific plasmid replicons with ARGs remains limited.
  pubmed Zhu W, Chen X, Shen H, Yang C 等 2026 Oct 置信度 0.82
• Genetic Etiology and Neurodevelopmental Outcomes in Children With Craniosynostosis: A 15-Year Single-Center Retrospective Study.
  The traditional distinction between syndromic and nonsyndromic craniosynostosis has guided clinical management, but recent genomic advances suggest these categories represent a continuous spectrum rather than discrete entities. Data on genetic etiologies and l…
  pubmed Joo S, Kang JW, Yang SW, Jang DH 等 2026 Aug 17 置信度 0.82
• Anti-CD320 Autoantibodies and Central Nervous System Vitamin B12 Deficiency in Idiopathic Myelopathy.
  Disorders affecting the spinal cord (myelopathies) can cause severe disability. Despite diagnostic advances, approximately 12% to 18% of myelopathy cases continue to elude an etiological diagnosis, hampering effective treatment.
  pubmed Pluvinage JV, Acero-Garces D, Greco G, Moseley CE 等 2026 Aug 17 置信度 0.82
• Enhanced decellularization of human amniotic membrane: optimizing dna clearance and protein retention for clinical applications.
  The clinical efficacy of decellularized human amniotic membrane (dHAM) as a bioactive scaffold depends on the thorough removal of immunogenic components while maintaining the functional integrity of the extracellular matrix (ECM). This study aims to evaluate t…
  pubmed Aykora D, Erbil G, Yülek Ö, Beyazıt F 等 2026 Aug 17 置信度 0.82
• Epidemiological characteristics and structural-functional implications of spike protein variations in a bovine coronavirus isolate from diarrheic calves.
  Bovine coronavirus (BCoV) is an important pathogen associated with enteric disease in calves, contributing to significant economic losses worldwide. To provide an updated overview of BCoV epidemiology, we conducted a systematic review and meta-analysis of stud…
  pubmed Teng F, Li X, Zhao H, Ma Y 等 2026 Dec 置信度 0.82
• From the grassroots up: Redefining Public Health Surveillance in Nigeria through Community Action Networks.
  Gaps in community-level surveillance continue to limit early detection of communicable diseases in Nigeria, particularly for zoonotic and emerging infections. Strengthening participatory, One-Health (OH)-oriented surveillance systems is critical for improving …
  pubmed Cadmus EO, Besong MA, Olaleye FE, Owoicho SA 等 2026 May-Jun 置信度 0.82
• Influence of Implant Positioning on Peri-Implant Colonization by Porphyromonas gingivalis and Fusobacterium nucleatum: A Prospective Longitudinal Observational Cohort Study.
   Peri-implant microbial colonization plays a critical role in the maintenance of peri-implant tissue health and the development of peri-implant diseases. Implant positioning relative to crestal bone may influence the peri-implant microenvironment and affe…
  pubmed Pabri R, Sharma G, Savoriya G, Daiya M 等 2026 Jul 置信度 0.82
• [Latest Classification and Management of Circumscribed Astrocytic Gliomas].
  The 2021 World Health Organization (WHO) classification of tumors of the central nervous system (CNS5) marks a major shift toward molecularly integrated diagnostics, distinguishing circumscribed astrocytic gliomas and glioneuronal tumors from diffuse gliomas b…
  pubmed Yamasaki T, Kurozumi K 2026 Jul 置信度 0.82
• Staged cardiac and pulmonary resection for primary cardiac sarcoma.
  Primary cardiac sarcoma is exceptionally rare, and the need for anatomical lung resection to achieve complete removal markedly increases operative risk. To reduce bleeding into the pneumonectomy space and mitigate hazards of single-stage cardiac and pulmonary …
  pubmed Atkins MD, Székely M, Del Val FR, Lopez-Trevino MG 等 2026 Aug 置信度 0.82
• Feasibility of flexible and navigable suction ureteral access sheath in pediatric ureteroscopy: A systematic review from the European Association of Urology Section of Endourology.
  The introduction of a flexible and navigable suction ureteral access sheath (FANS-UAS) has further enhanced retrograde intrarenal surgery (RIRS) by improving kidney stone clearance and reducing operative challenges. However, evidence for its use in the pediatr…
  pubmed Talyshinskii A, Juliebø-Jones P, Gauhar V, Yuen SKK 等 2026 Jul 置信度 0.82
• Crisis readiness for rare disease populations: learnings and recommendations by the European Reference Networks.
  Patients with rare diseases are particularly vulnerable during emergencies due to dependence on specialised care pathways, medicines, and expertise. European Reference Networks (ERNs) for rare and complex diseases have operated since 2017 and were confronted w…
  pubmed Dollfus H, Arzimanoglou A, Evangelista T, Graessner H 等 2026 Oct 置信度 0.82
• The bacterial microbiota of the spontaneously fermented Ethiopian honey wine, Tej.
  The honey wine ( Tej ) is the most widely consumed traditionally fermented alcoholic beverage in Ethiopia. Different classes of microorganisms including lactic acid bacteria and yeasts have been reported to be involved in its fermentation. The microbial compos…
  pubmed Getachew T, Birri DJ, Ashenafi M, Tigu F 等 2026 Sep 置信度 0.82
• Corrigendum to "Oleandrin-mediated suppression of MELK induces apoptosis, autophagy, and ferroptosis in human non-small cell lung cancer cells" [Phytomedicine. 2025 Nov;147:157173].
  pubmed Omer EA, Zhou M, Roos W, Rashan LJ 等 2026 Oct 置信度 0.82
• First detection and transatlantic introduction of Influenza A(H3N2) subclade K (J.2.4.1) into Ecuador: insights from genomic sentinel surveillance.
  The rapid evolution of Influenza A(H3N2) requires constant global monitoring. This study analyzes the genomic characteristics and the first introduction of the emerging subclade K (J.2.4.1) in Ecuador, utilizing publicly available data to trace its intercontin…
  pubmed Bruno A, de Mora D, Olmedo M, Garcés J 等 2026 置信度 0.82
• Sustainable Community-Wide Model to Enhance Cancer Data Usage and Utility.
  Despite vast investments in data collection, generation, and sharing from childhood cancer studies, for example, Gabriella Miller Kids First Research Program, Childhood Cancer Data Initiative, and other efforts, secondary use of data remains a challenge especi…
  pubmed Boja ES, Ghosh M, Huang Y, Mamie Lih TS 等 2026 Jul-Sep 置信度 0.82
• Evidence of Efficacy for Neoadjuvant Immunochemotherapy in a Rare Subgroup: Two Cases of Pathological Complete Response in Locally Advanced HER2-Mutant NSCLC.
  Neoadjuvant immunochemotherapy (nICT) has been recommended as the standard regimen for locally advanced non-small cell lung cancer (NSCLC) without actionable genomic alterations. However, the efficacy of nICT for patients harboring human epidermal growth facto…
  pubmed Yue H, Bian D, Zhang P 2026 Jan-Dec 置信度 0.82
• Persistent circulation of Rift Valley fever virus lineage C in Rwanda, 2022-2025.
  Rwanda has experienced recurrent Rift Valley fever virus outbreaks in the last decade. In this study, we investigated whether these outbreaks resulted from repeated introductions or sustained local circulation. We generated RVFV whole-genome sequences from liv…
  pubmed Udahemuka JC, Cassidy H, Schuele L, Uwibambe E 等 2026 Dec 置信度 0.82
• Simultaneous detection of classic and natural recombinant myxoma virus strains in European brown hare population in West Hungary.
  Historically, Myxomatosis was a severe disease in the European wild and domesticated rabbits ( Oryctolagus cuniculus ) with only a few reported cases in hares. Recently, beside the classic myxoma virus strains, new natural recombinant strains have emerged. The…
  pubmed Kollár A, Kaszab E, Fehér E, Gál J 等 2026 置信度 0.82
• Society for Maternal-Fetal Medicine Consult Series #74: Cell-free DNA screening for aneuploidies: Updated guidance.
  In this Consult, we provide updated guidance on the evolving applications of cell-free DNA (cfDNA) screening, including its use in detecting sex chromosome aneuploidies and microdeletions and its application in multifetal gestations. We compare cfDNA test perf…
  pubmed Society for Maternal‐Fetal Medicine (SMFM), Rink BD, Dugoff L, Kuller JA 等 2025 Nov 置信度 0.82
• Clinical and genetic characteristics of hypoparathyroidism, deafness, and renal dysplasia syndrome in a chronic kidney disease cohort.
  Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder caused by GATA-binding protein 3 (GATA3) haploinsufficiency. Although the clinical triad is well recognized, the phenotype is often incomplete, making clinic…
  pubmed Tanaka Y, Nagano C, Asagai Y, Hanafusa H 等 2026 Aug 13 置信度 0.82
• Functional atlas of vertebrate viral RNA elements that stabilize RNA and enhance translation.
  Viruses encode diverse regulatory elements, but their breadth and mechanisms remain poorly defined. To address this gap, we performed massively parallel reporter assays spanning ∼200,000 genomic segments from 297 vertebrate-infecting viral genera. We id…
  pubmed Seo JJ, Lee C, Lim D, Jeong M 等 2026 Aug 13 置信度 0.82
• Improving the reliability of polygenic risk score-based prediction for cardiovascular and renal complications across ancestries in type 2 diabetes using Mondrian Cross-Conformal Prediction.
  Polygenic risk scores (PRS) developed in European populations often show reduced predictive performance in non-European populations, limiting their clinical utility. This lack of transferability across ancestries remains a major challenge in genomic medicine a…
  pubmed Kodji E, Attaoua R, Haloui M, Hishmih C 等 2026 Aug 置信度 0.82
• Outbreak of aztreonam-avibactam-resistant NDM-5-producing Escherichia coli isolates in a hospital of Paris.
  The emergence of aztreonam-avibactam resistance among NDM-producing Escherichia coli represents a major therapeutic and infection control concern. Four cases of aztreonam-avibactam-resistant (AZAR) NDM-producing E. coli , recovered from three blood cultures an…
  pubmed Faraut Derouin V, Souhail B, Charlier C, Gaultier S 等 2026 Aug 13 置信度 0.82
• Emergence and Genomic Characterisation of Influenza Virus A(H3N2) Subclade K in Saudi Arabia: Dominant Circulation With Fixed HA1 Substitutions and High-Frequency HA-NA Clade Association, 2025-2026.
  The 2025-2026 Northern Hemisphere influenza season was characterised globally by rapid expansion of A(H3N2) subclade K. Saudi Arabia reported an A(H3N2)-dominant epidemic peaking in epidemiological Weeks 43-46 (20 October-16 November 2025), with national test …
  pubmed Naeem A, Hakami M, Alanazi KM, Alzahrani N 等 2026 Aug 置信度 0.82
• Whole-Genome Characterization of Rodent Coronaviruses (RCoVs) in Thailand, 2024-2025.
  Rodents are recognized as important reservoirs of coronaviruses, contributing to viral diversity and potential zoonotic emergence. However, data on rodent coronaviruses (RCoVs) in Thailand remained limited. This study aimed to determine the prevalence, genetic…
  pubmed Nasamran C, Chaiyawong S, Boonyapisitsopa S, Bunpapong N 等 2026 置信度 0.82
• Next-Generation Sequencing in Colorectal Cancer: Real-World Molecular Profiling and Clinical Correlations.
  Next-generation sequencing (NGS) has become a cornerstone of precision oncology in colorectal cancer (CRC), although its role in routine patient stratification remains incompletely defined. This retrospective single-centre study characterised the molecular lan…
  pubmed Cunha A, Robalo C, Lemos C, Lamas NJ 等 2026 Aug 1 置信度 0.82
• Genome-Wide Identification of the SWEET Gene Family in Peanut and Prediction of Candidate AhSWEET Genes Associated with Seed Protein Accumulation.
  The cultivated peanut ( Arachis hypogaea L.) is an important oilseed and economic crop worldwide, with seed protein content being a key target for quality improvement. The Sugars Will Eventually be Exported Transporter (SWEET) gene family encodes sugar transpo…
  pubmed He L, Qu P, Li X, Zhao H 等 2026 Aug 1 置信度 0.82
• Genomic Characterization and Taxonomic Classification of Mycobacterium shunyiense sp. nov., a Novel Nontuberculous Mycobacterial Species from a Human Respiratory Specimen.
  Non-tuberculous mycobacteria (NTM) are increasingly recognized as opportunistic pathogens, yet accurate species identification remains challenging. In this study, two clinical isolates, 19-857 T and 20-525, obtained from patients with suspected pulmonary tuber…
  pubmed Deng Y, Yang XY, Wang NH, Li B 等 2026 Aug 1 置信度 0.82
• Modeling Inherited Disorders of Post-Lanosterol Cholesterol Biosynthesis: From Animal Models to Patient-Derived Stem Cells.
  Altered post-lanosterol cholesterol biosynthesis causes a heterogeneous group of rare inherited metabolic disorders, including Smith-Lemli-Opitz syndrome, desmosterolosis, lathosterolosis, and congenital hemidysplasia with ichthyosiform nevus and limb defects …
  pubmed Akhmetzyanova E, Nasybullina E, Rizvanov A, Mukhamedshina Y 2026 Jul 30 置信度 0.82
• PARP Inhibitor Sensitivity in Tumors Harboring Non-BRCA Homologous Recombination Gene Alterations: Current Evidence Across Ovarian, Breast, Prostate, and Pancreatic Cancers.
  Poly(ADP-ribose) polymerase inhibitors (PARPis) have demonstrated remarkable efficacy in tumors carrying BRCA1/2 pathogenic variants (PVs) through the mechanism of synthetic lethality. PVs in other homologous recombination (HR) genes may also impair homologous…
  pubmed Dos Santos ES, Cicilini AL, Simões MFE, Baz M 等 2026 Jul 28 置信度 0.82
• Genome-Wide Identification and Functional Verification of Core Berberine Bridge-like Enzyme Genes for Benzylisoquinoline Alkaloid Biosynthesis in Corydalis saxicola Bunting.
  Benzylisoquinoline alkaloids (BIAs) are significant defensive and pharmaceutical metabolites found in medicinal plants of the Papaveraceae family. Among these, dehydrocavidine is a distinctive bioactive constituent of Corydalis saxicola Bunting, an endangered …
  pubmed Kang L, Liu H, Zhu D, Li C 等 2026 Jul 27 置信度 0.82
• Inflamed Yet Immune-Evasive? A Transcriptomic Meta-Analysis Identifies Conserved Inflammatory, Developmental, and Neuronal Signatures Associated with Polyploid Giant Cancer Cells.
  Polyploid giant cancer cells (PGCCs) are increasingly recognized as major drivers of therapy resistance and tumor relapse, yet the conserved molecular programs underlying their persistence remain incompletely defined. To identify genes consistently deregulated…
  pubmed Anatskaya OV, Vinogradov AE 2026 Jul 26 置信度 0.82
• Genetic Landscape of Lynch Syndrome in a High-Risk Serbian Cohort: Predominance of MLH1 Variants and Implications for Risk-Based Testing.
  Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome, caused by germline pathogenic or likely pathogenic variants (PV/LPV) in mismatch repair (MMR) genes. Data on the spectrum of LS-associated variants in Slavic populations, inclu…
  pubmed Djordjic Crnogorac M, Karadzic V, Cato T, Cavic M 等 2026 Jul 25 置信度 0.82
• Comprehensive Genome Identification of the PHD Gene Family in Panax ginseng and Expression Analysis of PgPHD Genes in Response to MeJA.
  Plant homeodomain (PHD) finger proteins are important histone modification readers that play broad roles in the epigenetic regulation of plant development and stress responses. However, the PHD finger gene family has not been systematically identified in Panax…
  pubmed Xu Z, Guan D, Fan M, Li Y 等 2026 Jul 30 置信度 0.82
• Four Decades of Cytochrome P450 Research in Africa: A Historical Overview of Scientific Contributions, Research Trends, and Future Directions.
  Cytochrome P450 monooxygenases (CYPs/P450s) are versatile heme-containing enzymes involved in drug metabolism, steroidogenesis, secondary metabolite biosynthesis, and biotechnology. Although African researchers have contributed to P450 research for nearly four…
  pubmed Syed K 2026 Jul 28 置信度 0.82
• Mycotoxin Occurrence and Microbiological Quality of Maize Silage Supplemented with Insect Meals for Potential Use in Waterfowl Nutrition.
  Whole crop maize silage may represent a complementary feed material in waterfowl nutrition, but its hygienic quality and mycotoxin profile remain important safety considerations. This study evaluated the microbiological quality, occurrence, and concentrations …
  pubmed Džima M, Kačániová M, Bíro D, Šimko M 等 2026 Aug 3 置信度 0.82
• Wheat Biofortification for Enhancing Iron, Zinc, and Protein: The Role of Mutation Breeding.
  Biofortification of wheat has emerged as a sustainable strategy to combat global micronutrient deficiencies, particularly iron (Fe) and zinc (Zn) deficiency, while simultaneously improving grain protein quality. Among available approaches, mutation breeding ha…
  pubmed Doktyrbay G, Atabayeva S, Asrandina S, Shoinbekova S 等 2026 Jul 26 置信度 0.82
• Genome-Wide Identification of the Wheat GAD Gene Family Reveals TaGAD1-Mediated Salt Tolerance via GABA-Dependent ROS Homeostasis.
  Wheat ( Triticum aestivum L.) is a major food crop that is severely affected by salt stress, resulting in significant yield losses. Glutamic acid decarboxylase (GAD) catalyzes the irreversible conversion of glutamic acid to γ-aminobutyric acid (GABA) and…
  pubmed Liu X, Wang M, Zhou J, Li Y 等 2026 Jul 25 置信度 0.82
• Harnessing Trichoderma Species for Sustainable Biocontrol: Mechanisms, Formulation Strategies, Commercialization, and Field Applications.
  Trichoderma species are widely investigated and commercially applied as eco-friendly biocontrol agents in sustainable agriculture. These filamentous fungi protect plants through multiple complementary mechanisms, including mycoparasitism, antibiosis, competiti…
  pubmed Otithi SMBA, Rana MS, Islam MS, Zaki RM 等 2026 Jul 23 置信度 0.82
• NLRP7 in Hydatidiform Mole and Gestational Trophoblastic Neoplasia: From Maternal-Effect Biology to a Genetic Permissiveness Framework for Integrated Cancer Surveillance and Reproductive Decision-Making.
  Background/Objectives : Biallelic mutations of NLRP7 , a maternal-effect gene encoding a key component of the subcortical maternal complex, are the major monogenic cause of recurrent hydatidiform mole (RHM) and confer a substantial lifetime risk of gestational…
  pubmed Xue W, Chen T, Xiang Y, Yang J 2026 Jul 24 置信度 0.82
• Technofunctional Properties and Proteomic Profiling of Sesame Cake Protein Isolates Obtained by Green Extraction Methods and Treated with Cold Plasma.
  The demand for plant-based proteins has been steadily increasing; however, their functionality when applied in food product formulations requires comprehensive evaluation and, when necessary, deliberate modification to ensure that it mimics that of animal-deri…
  pubmed Acar EG, Ozturk ON, Kırkın C, Sonmez E 等 2026 Jul 29 置信度 0.82
• Ullucus tuberosus: A Review of Its Biology, Nutritional Profile, Phytochemistry, and Food Industry Applications.
  Ulluco ( Ullucus tuberosus ), the second most economically important Andean tuber after potato, has been cultivated for over 5500 years. Despite its resistance to frost, drought, and high altitudes, as well as its biochemically complex profile, ulluco remains …
  pubmed Bolaños-Narciso A, Asto-Rodriguez E, Paucar-Menacho LM, Castillo-Martinez WE 2026 Jul 31 置信度 0.82
• Genetically Modified MSCs for Targeted Regeneration: Balancing Efficacy, Biosafety, and GMP Standardization.
  Mesenchymal stromal cells (MSCs) are a versatile platform for regenerative medicine and gene delivery because they combine multipotency, immunoregulatory activity, and injury-directed trafficking. Translation is nevertheless limited by donor- and tissue-depend…
  pubmed Kitaeva KV, Filin IY, Rizvanov AA, Turdikulova S 等 2026 Aug 3 置信度 0.82
• Microbiota-Derived Corisin Is Elevated in Early Cervical Neoplasia and Drives Pathogenic Cellular Programs.
  Cervical cancer remains a major global health challenge and a leading cause of gynecological cancer-related mortality, particularly in developing countries. Although persistent human papillomavirus infection is the primary driver of cervical carcinogenesis, ho…
  pubmed Watashige N, Kubo-Kaneda M, Makino M, Kato M 等 2026 Jul 28 置信度 0.82
• Use of Next-Generation Sequencing and Whole-Exome Sequencing in the Diagnosis of Adult-Onset Familial Intrahepatic Cholestasis: Challenges in Interpreting Variants of Uncertain Significance.
  Progressive Familial Intrahepatic Cholestasis (PFIC) is a rare liver disorder that, although typically present in childhood, can also occur in adulthood. Early diagnosis is crucial for appropriate clinical management, prognostic assessment, and therapeutic dec…
  pubmed Conti A, Gabrielli F, Ferrari S, Vaisfeld A 等 2026 Jul 25 置信度 0.82
• Genome-wide DNA methylation profiling of triple-negative breast cancer uncovers epigenetic biomarkers of tumor identity and the immune microenvironment.
  DNA methylation deregulation is an essential feature of tumor biology, influencing cancer formation and pathogenesis. Analyses of DNA methylation in bulk cancer specimens are challenging due to the high data dimensionality, noise, and mixture of different cell…
  pubmed Sasiain I, Nacer DF, Jönsson M, Vallon-Christersson J 等 2026 Aug 12 置信度 0.82
• Effectiveness of Omicron JN.1 vaccination against infection with JN.1-derived SARS-CoV-2 subvariants in a prospective cohort study in the Netherlands.
  We estimated vaccine effectiveness (VE) of JN.1 COVID-19 vaccination against SARS-CoV-2 infection by (sub)variant between 23 September 2024 and 23 February 2025.
  pubmed Huiberts AJ, Eggink D, de Gier B, Karens T 等 2026 Sep 17 置信度 0.82
• In silico screening of anti-atherosclerotic compounds from Morus alba leaves by machine learning and network pharmacology.
  This study integrates machine learning with network pharmacology, molecular docking, and molecular dynamics simulations to screen bioactive compounds from Mulberry leaves and elucidate their potential mechanisms against atherosclerosis (AS).
  pubmed Gan M, Liu R, Liu H, Jia Z 等 2026 Aug 6 置信度 0.82
• Acute respiratory viral diseases in Amazonas, Brazil: epidemiological patterns and implications for health surveillance.
  Acute respiratory viral diseases are a major public health challenge in the Brazilian Amazon, where ecological, logistical, and social factors shape patterns of transmission and response.
  pubmed Teixeira R, Nery F, Carvalho E, Neves IAV 等 2026 置信度 0.82
• Vutrisiran Treatment and Changes in Cardiac Parameters and Amyloid Burden Assessed by Cardiovascular MRI.
  Transthyretin amyloid cardiomyopathy (ATTR-CM) is caused by extracellular myocardial ATTR amyloid infiltration. Vutrisiran, an RNA interference therapeutic that suppresses hepatic TTR production, met its primary end point in the HELIOS-B (A Study to Evaluate V…
  pubmed Razvi Y, Sheikh A, Patel RK, Achten A 等 2026 Aug 12 置信度 0.82
• Gestational Diabetes and Postpartum Cardiovascular, Kidney, and Metabolic Disorders.
  Gestational diabetes is associated with future cardiometabolic risk, but postpartum evidence across the cardiovascular-kidney-metabolic (CKM) disorder spectrum remains limited.
  pubmed Liu L, Lu JA, Velasquez EE, Ananth CV 等 2026 Aug 3 置信度 0.82
• Simplified Inhouse Nanoweb Membrane Enrichment Coupled Viral Whole Genome Shotgun Metagenomics Approach for Waste Water Surveillance.
  Wastewater/sewage represents a highly complex environmental matrix and harbors various viruses including viruses of epidemic and pandemic potential like Influenza A and, SARS-CoV-2. The limitations of available methods for sample concentration are cost, effici…
  pubmed Sharma S, Sharma PK, Gupta E, Dash PK 等 2026 Aug 12 置信度 0.82
• Computational techniques to study breast cancer scaffolds for antiangiogenesis: a review.
  Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide. Tumor angiogenesis plays a crucial role in breast cancer progression, making angiogenesis-associated pathways attractive therapeutic targets. Computational drug …
  pubmed Singh R, Gupta N, Luxmi R 2026 Aug 12 置信度 0.82
• Protective mechanisms of Sirtuin Family in myocardial ischemia-reperfusion injury and translational therapeutic perspectives.
  Myocardial ischemia-reperfusion injury (MIRI) is an inevitable pathological complication following reperfusion therapy for acute myocardial infarction. Massive reactive oxygen species burst, mitochondrial dysfunction, inflammatory cascade activation and multip…
  pubmed Xue T, Wang S, Zhu X, Luo J 等 2026 Aug 12 置信度 0.82
• Receptor-tethered orthogonal IL-2 enhances regulatory T cell therapy.
  Regulatory T cell (Treg) therapy is an emerging platform for controlling immune overactivation. Persistence of infused Tregs is limited by insufficient IL-2, which is essential for Treg survival and function. IL-2 activates many immune cells, imposing a challe…
  pubmed Indart AC, Lyu H, Nguyen VQ, Rosenthal W 等 2026 Sep 7 置信度 0.82
• Integrating Genome-Wide Association Study and Transcriptomics to Unravel the Genetic Regulatory Mechanism of Grape Fruit Shape and Screen Hormone-Related Candidate Genes.
  Grape berry shape is an important agronomic trait that is closely related to its commercial value. In this study, we performed a genome-wide association study (GWAS) and transcriptome analysis combined with exogenous hormone treatment to further explore the ge…
  pubmed Guo YF, Chen JB, Hu LL, Zhao YY 等 2026 Aug 12 置信度 0.82
• Genomic surveillance of enterovirus D68 circulating in 2025 reveals the emergence of a novel A2/B3 recombinant lineage.
  Enterovirus D68 (EV-D68) has re-emerged over the past decade as a significant respiratory pathogen associated with severe respiratory disease and acute flaccid myelitis. Its circulation has typically followed a biennial pattern, with predominance in late summe…
  pubmed Fall A, Morris CP, Elgazayerly O, Wu T 等 2026 Aug 12 置信度 0.82
• Evaluation of Oxford nanopore sequencing for antimicrobial resistance surveillance in Salmonella: comparison with phenotypic antimicrobial susceptibility in a large-scale study.
  Salmonella is a major zoonotic foodborne pathogen, and antimicrobial resistance (AMR) in Salmonella presents a significant public health challenge. Compared with conventional antimicrobial susceptibility testing (AST), whole-genome sequencing (WGS) provides a …
  pubmed Hong Y-P, Liao Y-S, Wang Y-W, Kuo S-C 等 2026 Aug 12 置信度 0.82
• National Coordinated Care and Translational Research Program for Uveal Melanoma Pilot: Infrastructure, Biobanking, and Challenges in Liquid Biopsy Implementation in a Latin American Country.
  Uveal melanoma (UM) is a rare malignancy in Latin America (LA), where coordinated clinical and translational research initiatives remain limited. We evaluated the implementation of a national referral and biobanking program for UM in Chile and assessed the fea…
  pubmed Sepúlveda SA, Luna C, Labbé E, Mánquez ME 等 2026 Jun 26 置信度 0.82
• Immunocyte phenotypes underlying the causal autoimmune features in narcolepsy type 1.
  Narcolepsy is a neurological sleep disorder associated with immune response. However, the autoimmune basis for narcolepsy remains unclear. This study aimed to evaluate the causal relationship between immune cells and narcolepsy type 1 (NT1).
  pubmed Li T, Chen Y, Zhang P, Zhu Q 等 2026 Jul 31 置信度 0.82
• Current perspectives on circulating tumor DNA in breast cancer: a narrative review.
  In recent years, research and development of cell-free DNA (cfDNA) and circulating tumor DNA (ctDNA) as cancer biomarkers for use in diagnosis, prognosis, and monitoring of therapeutic responses have progressed. ctDNA has become an important focus for biomarke…
  pubmed Funasaka C, Naito Y 2026 置信度 0.82
• Evidence and gaps in tumor-agnostic therapies for breast cancer: a narrative review.
  Tumor-agnostic therapies enable treatment selection based on shared molecular alterations rather than tissue of origin and represent a central advancement in precision oncology. Since 2017, multiple U.S. Food and Drug Administration (FDA) approvals have valida…
  pubmed Jones DT, Nanda RK, Dhillon M, Hanspal A 等 2026 置信度 0.82
• Frequent antecedent nodules and diagnostic gaps in adrenocortical carcinoma.
  Adrenocortical carcinoma (ACC) is a rare and often fatal malignancy currently only cured by surgery. Large-scale studies have failed to capture benign to malignant transition events, and patients often present with metastatic disease. These observations sugges…
  pubmed Mohan DR, Weimholt C, Brunt LM, Brown TC 等 2026 Sep 置信度 0.82
• Bioethical challenges in the implementation of targeted anti-tumor therapies in low-resource settings: a perspective from Latin America.
  Precision oncology has revolutionized cancer care in high-income countries, but its implementation in Latin American low-resource settings faces profound bioethical dilemmas. This study analyzes these challenges through the lens of social justice and equity. A…
  pubmed Chaux A 2026 置信度 0.82
• Host systemic metabolism and cancer metabolic vulnerabilities: mechanisms and therapeutic opportunities.
  Central molecular mediators-including hypoxia-inducible factors (HIF-1α/HIF-2α), MYC, wild-type and mutant p53, NF-κB, STAT3, SREBPs, NRF2, and KRAS-orchestrate these pathways by linking nutrient availability to oncogenic signalling, epigenet…
  pubmed Mir R, Barnawi J, Algehainy NA, M Jalal M 等 2026 置信度 0.82
• Hierarchical classification of acute and chronic osteoporotic vertebral compression fractures of the lumbar spine using X-ray images.
  To develop and validate a hierarchical deep learning model for differentiating acute and chronic lumbar osteoporotic vertebral compression fractures (OVCFs) using X-ray images.
  pubmed Kim J, Shin K, An S, Lee S 等 2026 Aug 11 置信度 0.82
• Drought stress reshapes the genetic architecture of fiber quality and developmental traits in Egyptian cotton (Gossypium barbadense L.): a line × tester analysis under contrasting irrigation regimes.
  Water scarcity is an increasing threat to Egyptian cotton production, yet the mechanisms by which drought stress modifies the genetic control of fiber development and plant architecture remain poorly characterized. This study investigated how water deficit alt…
  pubmed Mohamed AAE, Yehia WMB, Hamoda A, Jabr RME 等 2026 Aug 11 置信度 0.82
• Genomic epidemiology of multidrug-resistant and ESBL-producing Proteus mirabilis in a military referral hospital in Ethiopia.
  Multidrug-resistant Proteus mirabilis has emerged as an important healthcare-associated pathogen; however, genomic epidemiological data from sub-Saharan Africa remain limited, particularly in military hospital settings. This study aimed to characterize the phe…
  pubmed Yusuf YM, Desta AF, Ayana D, Aychegrew HN 等 2026 置信度 0.82
• A course-undergraduate research experience (CURE) to explore the effect of structural variants on gene expression in C. elegans balancers.
  Bioinformatics, a discipline at the crossroads of Biology and Computational Sciences, also referred to as Computational Biology, is widely spread in research programs. However, implementing any Bioinformatics projects requires the ability to comprehend biologi…
  pubmed Maroilley T, Barbosa VRA, Mascarenhas R, Ferris S 等 2026 置信度 0.82
• The first complete genome sequence of iris yellow spot virus from South America and comparative analysis with isolates of different geographic origin.
  We report the first complete nucleotide sequence of an isolate of iris yellow spot virus (IYSV; Orthotospovirus iridimaculaflavi) from Brazil. Isolate Br-25 was collected in 2025 in Imbuia, Santa Catarina, from symptomatic onion scapes. The genome of IYSV-Br-2…
  pubmed Blawid R, de Araújo ER, Geremias LD, Knierim D 等 2026 Aug 11 置信度 0.82
• Emergence and local dissemination of NDM-14-producing Klebsiella pneumoniae ST147: a phylodynamic and epidemiological investigation.
  NDM-14-producing Klebsiella pneumoniae ST147 has recently emerged as a high-risk clone in Europe, but its local dissemination dynamics remain poorly defined. We investigated a 6-month outbreak across three hospitals within a regional healthcare network in Lomb…
  pubmed Arcari G, Carbotti M, Pavesi R, Gigante P 等 2026 Aug 11 置信度 0.82
• Human PMS1-dependent non-canonical mismatch repair engages with MBD4 to repair methylated CpG deamination.
  CpG dinucleotides are mutational hotspots due to spontaneous deamination of 5-methylcytosine (5mC), resulting in T:G mismatches that can lead to CpG>TpG transitions. These mutations are a hallmark of aging and cancer and play a central role in the evolution…
  pubmed Le Ven A, Vanhuele S, Ganier O, Houy A 等 2026 Aug 10 置信度 0.82
• Viral metagenomic analysis of human bocavirus in pediatric pneumonia: detection pattern and genetic characterization.
  Human bocavirus (HBoV) is frequently detected in pediatric respiratory samples, but its clinical role remains difficult to interpret because of asymptomatic shedding and frequent co-detection with other pathogens. Data from bronchoalveolar lavage fluid (BALF),…
  pubmed Zhang J, Chen J, Hu M, Wang J 等 2026 置信度 0.82
• Operational, molecular, and cultural perspectives at the Neurological Foundation Human Brain Bank, New Zealand.
  Post-mortem human brain tissue is an irreplaceable resource for advancing understanding of the brain and neurological disease. Brain banks that collect, preserve, and distribute this tissue underpin discoveries across neuropathology, genomics, and emerging mol…
  pubmed Highet B, Singh-Bains M, Eszes M, Parker R 等 2026 置信度 0.82
• Carriage rate of CPE, ESBL-producing coliforms and MRSA in community settings in Suriname.
  Colonization by antimicrobial-resistant bacteria can cause difficult-to-treat infections, yet their carriage prevalence in Suriname is unknown. This cross-sectional study assessed intestinal community carriage and the molecular epidemiology of pathogens of pub…
  pubmed Rozemond CM, Adhin MR, Williams W, De Greeff SC 等 2026 Aug 置信度 0.82
• Genomic and physiological characterization of two heavy metal resistant bacteria isolated from a long-term metalliferous ecosystem.
  Remediation of mixed heavy metal contamination in U.S. nuclear legacy sites remains a persistent challenge. This study examines the genomic and functional traits of two newly isolated bacterial strains- Stenotrophomonas strain 3 and Pseudomonas strain 8-from t…
  pubmed Alex B, Xu X, Pathak A, Chauhan A 2025 置信度 0.82
• Charting a path for microbial conservation in the IUCN: report on "Conservation in a Microbial World" meeting in San Diego, CA, May 2025.
  In May 2025, the "Conservation in a Microbial World" conference was hosted at UC San Diego's Scripps Institution of Oceanography to address the lack of microbial representation in international conservation frameworks (i.e. International Union for Conservation…
  pubmed Kunselman E, Minnis V, Kodera S, Buschmann MM 等 2025 置信度 0.82