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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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Prior to 2024, highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses circulated predominantly in wild birds and poultry. In 2024 and 2025, 2.3.4.4b genotypes B3.13 and D1.1 were detected in United States dairy cattle. Using whole-genome and segment-spe…
preprints
2026
置信度 0.74
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Changes in gene expression and regulation are central to mammalian phenotypic evolution. Yet, distinguishing adaptive gene expression shifts from neutral divergence remains challenging. Here, we integrate comparative transcriptomics and regulatory genomics to …
preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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Here, we present a major advance of the OrthoFinder method. This extends OrthoFinder’s high accuracy comparative genomic framework to provide substantially enhanced scalability and accuracy. Specifically, we show that enhanced phylogenetic delineation of ortho…
preprints
2025
置信度 0.74
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ABSTRACT Focal cortical dysplasias (FCDs) are malformations of cortical development associated with drug-resistant focal epilepsy. We analysed surgical tissue from 28 consecutive cases recruited from adult and pediatric epilepsy surgery programs. We performed …
preprints
2025
置信度 0.74
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Abstract Wild relatives of wheat harbour genetic diversity essential for improving resilience to climate-driven stresses, yet their deployment is hampered by unresolved evolutionary relationships and the absence of reference genomes. Here we present a chromoso…
preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2024
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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preprints
2024
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2024
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2024
置信度 0.74
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preprints
2026
置信度 0.74
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Background The apolipoprotein E ( APOE ) locus is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD). Variation in APOE isoforms is known to have diverse pleiotropic effects on circulating lipids and other metabolites, but effects on the…
preprints
2026
置信度 0.74
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preprints
2024
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2026
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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preprints
2024
置信度 0.74
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We developed a haplotype-resolved, chromosome-scale genome assembly of the Urochloa humidicola (Rendle) Morrone & Zuloaga cultivar Tully, an apomictic C4 forage grass cultivated in the tropics worldwide. We assembled a 4.1 Gb genome into 48 chromosomes (2n = 8…
preprints
2025
置信度 0.74
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preprints
2025
置信度 0.74
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The nascent field of genomic AI is rapidly expanding with new models, benchmarks, and findings. As the field diversifies, there is an increased need for a common set of measurement tools and perspectives to standardize model evaluation. Here, we present a stat…
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Eyes S Robson, Nilah M. Ioannidis
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Abstract: Diabetic Kidney Disease (DKD) remains the leading cause of Chronic and End Stage Kidney Disease (ESKD) worldwide, with an increasing epidemiological burden. However, still, the disease awareness remains low, early diagnosis is difficult, and therapeu…
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Cary O. Harding, Michael Martinez
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2024-01-21T10:10:47Z
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2024-02-01T08:17:51Z
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2024-01-18T17:53:50Z
置信度 0.70
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Abstract Dinoflagellates are a remarkable group of protists, not only for their association with harmful algal blooms and coral reefs but also for their numerous characteristics deviating from the rules of eukaryotic biology. Genome research on dinoflagellates…
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Senjie Lin
2024-10-04T12:02:01Z
置信度 0.70
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Lori A.S. Snyder
2024-03-05T15:01:45Z
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Leila Jamal, Kimberly Zayhowski, Tala Berro, Kellan Baker
2024-04-17T16:58:41Z
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2024-04-26T02:20:32Z
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2024-08-02T04:15:56Z
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Sougata Bhattacharjee
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Federico Hoffmann
2024-11-28T09:16:41Z
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2024-08-02T04:19:17Z
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Pawel Michalak
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Chen Xiaoyan
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Seyoung Mun, Kyudong Han
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Ed Hollox
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Maeva Halgrain, Nelly Bernardet, Christelle Hennequet-Antier, Sophie Réhault-Godbert
2023-12-05T23:13:01Z
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Rachel M. Petersen, Amanda J. Lea
2024-03-13T10:39:17Z
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Jiah D. Lee, Woori Bae
2024-01-08T06:03:07Z
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Abstract Clustered miRNAs consist of two or more miRNAs transcribed together and may coordinately regulate gene expression. Differential expression of clustered miRNAs is found to be controlled by crosstalk of genetic or epigenetic mechanisms. It has been demo…
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Akshay Pramod Ware, Kapaettu Satyamoorthy, Bobby Paul
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The vast majority of population-scale genomic datasets collected to date consist of “bulk” samples obtained from heterogeneous tissues, reflecting mixtures of different cell types. In order to facilitate discovery at the cell-type level, there is a pressing ne…
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Abstract At the dawn of new millennium, policy makers and researchers focused on sustainable agricultural growth, aiming for food security and enhanced food quality. Several emerging scientific innovations hold the promise to meet the future challenges. Nanote…
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Erwinia (Enterobacterales: Erwiniaceae) are a group of cosmopolitan bacteria best known as the causative agents of various plant diseases. However, other species in this genus have been found to play important roles as insect endosymbionts supplementing the di…
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Abstract Background The Apetala 2/ethylene-responsive factor family has diverse functions that enhance development and torment resistance in the plant genome. In variation, the ethylene-responsive factor (ERF) family of TF’s genes is extensive in the crop geno…
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