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• Gate-based Mendelian randomization replicates Eggerthellaceae and nominates CD39⁺ regulatory T-cell and glial AHR nodes in Hirschsprung disease
  This OSF project is the analysis and reproducibility package for a pre-specified, gate-based Mendelian randomization (MR) study of Hirschsprung disease (HSCR). The study tests whether twelve bacterial genera, their tryptophan–indole and bile-acid metabolites, …
  datacite Kaili Chang, Enyang He, Xuehong Xia, Bowen Shi 等 2026 置信度 0.66 Medicine and Health SciencesLife SciencesEggerthellaHirschsprung diseaseMendelian randomization
• In Memoriam of Dr. Genady P. Cherepanov (1937–2021): A Memorial Archive of Scientific Contributions and Personal Legacy, including "The Blessing of the Superstar" Memoir
  This memorial archive documents the life, scientific contributions, and personal legacy of Dr. Genady P. Cherepanov (1937–2021), Honorary Life Member of the New York Academy of Sciences. Dr. Cherepanov was a distinguished mechanician whose primary contribution…
  datacite Cherepanov, Genady P. 2026 置信度 0.66 Fracture mechanics, invariant integrals, nanofracture mechanics, rolling friction, cosmology, NEOC model, hydraulic fracturing, scientific legacy, memorial archivememoir, personal history
• In Memoriam of Dr. Genady P. Cherepanov (1937–2021): A Memorial Archive of Scientific Contributions and Personal Legacy, including "The Blessing of the Superstar" Memoir
  This memorial archive documents the life, scientific contributions, and personal legacy of Dr. Genady P. Cherepanov (1937–2021), Honorary Life Member of the New York Academy of Sciences. Dr. Cherepanov was a distinguished mechanician whose primary contribution…
  datacite Cherepanov, Genady P. 2026 置信度 0.66 Fracture mechanics, invariant integrals, nanofracture mechanics, rolling friction, cosmology, NEOC model, hydraulic fracturing, scientific legacy, memorial archivememoir, personal history
• A New Fundamental Theoretical System and Model for Life Sciences That Provides Ultimate Explanations for All Challenges, Including Lifespan and Death
  Abstract and Excerpt - Part One. English Version. Title: A New Fundamental Theoretical System and Model for Life Sciences That Provides Ultimate Explanations for All Challenges, Including Lifespan and Death Keywords: Life, Biological Death, Aging, Late-stage D…
  datacite Yves Hugh 2025 置信度 0.66
• A New Fundamental Theoretical System and Model for Life Sciences That Provides Ultimate Explanations for All Challenges, Including Lifespan and Death
  Abstract and Excerpt - Part One. English Version. Title: A New Fundamental Theoretical System and Model for Life Sciences That Provides Ultimate Explanations for All Challenges, Including Lifespan and Death Keywords: Life, Biological Death, Aging, Late-stage D…
  datacite Yves Hugh 2025 置信度 0.66
• Statistics for the life sciences
  (Uploaded by Plazi for the Bat Literature Project) No abstract provided.
  datacite Samuels, Myra L., Witmer, Jeffrey A., Schaffner, Andrew A. 2012 置信度 0.66 BiodiversityMammaliaChiropteraChordataAnimalia
• Statistics for the life sciences
  (Uploaded by Plazi for the Bat Literature Project) No abstract provided.
  datacite Samuels, Myra L., Witmer, Jeffrey A., Schaffner, Andrew A. 2012 置信度 0.66 BiodiversityMammaliaChiropteraChordataAnimalia
• Abraham Davel in Lausanne, Switzerland
  Jean Daniel Abraham Davel, (Major Davel), (20 October 1670, Morrens - 24 April 1723, Vidy) was a soldier and patriot of Vaud. Abraham Davel, after studying in Lausanne, became a notary and land commissioner. In 1692, he began his military career in the service…
  datacite Scan-the-World 2026 置信度 0.66 Sculpture
• HemOncKB CC BY subset
  This dataset is a subset of the full HemOncKB centered on the Component concept and its relationships and hierarchies. It also includes all Conditions from the HemOncKB. Components are mapped to ATC, HCPCS, NDC, and RxNorm/RxNorm Extension codes and Conditions…
  datacite Warner MD, MS, Jeremy 2021 置信度 0.66 Medicine, Health and Life SciencesNeoplasmsControlled vocabulary
• HemOncKB
  The HemOncKB describes data and metadata related to systemic anticancer drugs and regimens. The core HemOncKB tables follow the OMOP Common Data Model format and specifications. Additional ancillary tables provide more complex data structures which are not eas…
  datacite Jeremy Warner MD, MS 2021 置信度 0.66 Computer and Information ScienceMedicine, Health and Life SciencesNeoplasmsControlled vocabularyCancer
• Weaving Sovereignty: Theoretical Framework and Experimental Exploration
  Weaving Sovereignty is the institutional framework within the Meaning Civilization theoretical system that ensures human autonomy, reversibility, and sovereignty in complex networked systems. This project systematically documents its theoretical construction (…
  datacite Jing Cheng 2026 置信度 0.66 BusinessPhysical Sciences and MathematicsLife SciencesArts and HumanitiesEducation
• Bust of Albert Pakh
  He dealt with other nations is its literature, and Gyulai Pal believes that the Hungarian public life and literature impression among some European spirit mixed with.At the end of August 1844 he went to Budapest jurátusnak, from late August to mid-February 184…
  datacite Scan-the-World 2026 置信度 0.66 bustman
• Structural and Functional Organization of the Eukaryotic Cell: Organelles, Protein Synthesis, Membrane Transport, and Cellular Processes
  This educational resource provides a comprehensive overview of the structural and functional organization of eukaryotic cells. It introduces the fundamental characteristics of plant and animal cells, describes the structure and function of major cellular organ…
  datacite Sri Wijebandara, Rishmi Ayodhya 2024 置信度 0.66 Cell Biology Eukaryotic Cell Cell Structure Cell Organelles Plant Cell Animal Cell Nucleus Mitochondria Ribosome Endoplasmic Reticulum Golgi Apparatus Lysosome Peroxisome Chloroplast Vacuole Cell Membrane Cytoskeleton Endomembrane System Protein Synthesis Protein Biogenesis Protein Transport Transcription Translation Gene Expression Membrane Transport Endocytosis Exocytosis Pinocytosis Phagocytosis Receptor-Mediated Endocytosis Intracellular Transport Molecular Biology Biotechnology Genetics Life Sciences Undergraduate Education
• Structural and Functional Organization of the Eukaryotic Cell: Organelles, Protein Synthesis, Membrane Transport, and Cellular Processes
  This educational resource provides a comprehensive overview of the structural and functional organization of eukaryotic cells. It introduces the fundamental characteristics of plant and animal cells, describes the structure and function of major cellular organ…
  datacite Sri Wijebandara, Rishmi Ayodhya 2024 置信度 0.66 Cell Biology Eukaryotic Cell Cell Structure Cell Organelles Plant Cell Animal Cell Nucleus Mitochondria Ribosome Endoplasmic Reticulum Golgi Apparatus Lysosome Peroxisome Chloroplast Vacuole Cell Membrane Cytoskeleton Endomembrane System Protein Synthesis Protein Biogenesis Protein Transport Transcription Translation Gene Expression Membrane Transport Endocytosis Exocytosis Pinocytosis Phagocytosis Receptor-Mediated Endocytosis Intracellular Transport Molecular Biology Biotechnology Genetics Life Sciences Undergraduate Education
• Molecular Basis of Genetic Information: DNA, RNA, Gene Expression, Cell Cycle, Mitosis, Meiosis, and Genetic Diversity
  This educational resource provides a comprehensive overview of the molecular basis of genetic information and its role in inheritance, gene expression, and cellular reproduction. It covers the structure and function of DNA and RNA, chromatin organization, chro…
  datacite Sri Wijebandara, Rishmi Ayodhya 2024 置信度 0.66 Genetics Molecular Genetics Cell Biology Molecular Biology DNA RNA DNA Structure RNA Structure Chromatin Chromosomes Gene Expression Transcription Post-Transcriptional Modification Translation Post-Translational Modification Protein Synthesis Cell Cycle Cell Cycle Regulation Mitosis Meiosis Chromosome Segregation Crossing Over Independent Assortment Fertilization Genetic Diversity Inheritance Eukaryotic Cells Cell Division Biotechnology Life Sciences Undergraduate Education
• Molecular Basis of Genetic Information: DNA, RNA, Gene Expression, Cell Cycle, Mitosis, Meiosis, and Genetic Diversity
  This educational resource provides a comprehensive overview of the molecular basis of genetic information and its role in inheritance, gene expression, and cellular reproduction. It covers the structure and function of DNA and RNA, chromatin organization, chro…
  datacite Sri Wijebandara, Rishmi Ayodhya 2024 置信度 0.66 Genetics Molecular Genetics Cell Biology Molecular Biology DNA RNA DNA Structure RNA Structure Chromatin Chromosomes Gene Expression Transcription Post-Transcriptional Modification Translation Post-Translational Modification Protein Synthesis Cell Cycle Cell Cycle Regulation Mitosis Meiosis Chromosome Segregation Crossing Over Independent Assortment Fertilization Genetic Diversity Inheritance Eukaryotic Cells Cell Division Biotechnology Life Sciences Undergraduate Education
• Active Zeroing: Theoretical Framework and Experimental Exploration
  Active Zeroing is the core phase of the Spectrum Spiral Cognitive Theory, the operational mechanism of reversibility in Reversible Civilization Theory, and a key capacity for human sovereignty in Meaning Intelligence. This project systematically integrates the…
  datacite Jing Cheng 2026 置信度 0.66 BusinessLife SciencesSocial and Behavioral SciencesAZ
• Bust of Albert Pakh
  He dealt with other nations is its literature, and Gyulai Pal believes that the Hungarian public life and literature impression among some European spirit mixed with.At the end of August 1844 he went to Budapest jurátusnak, from late August to mid-February 184…
  datacite Scan-the-World 2026 置信度 0.66 bustmanSculpture
• Bust of Albert Pakh
  He dealt with other nations is its literature, and Gyulai Pal believes that the Hungarian public life and literature impression among some European spirit mixed with.At the end of August 1844 he went to Budapest jurátusnak, from late August to mid-February 184…
  datacite Scan-the-World 2026 置信度 0.66 bustmanSculpture
• The Continuity of Life and the Right to Life: A Conceptual Framework
  This article proposes a conceptual framework for understanding the relationship between the right to life and the conditions necessary for the continuation of human life. The article begins from the premise that human life is not a static condition but a conti…
  datacite TAMER, Güneş Başar 2026 置信度 0.66 right to lifecontinuity of lifeLife Continuity Frameworkbasic living conditionsfood
• The Continuity of Life and the Right to Life: A Conceptual Framework
  This article proposes a conceptual framework for understanding the relationship between the right to life and the conditions necessary for the continuation of human life. The article begins from the premise that human life is not a static condition but a conti…
  datacite TAMER, Güneş Başar 2026 置信度 0.66 right to lifecontinuity of lifeLife Continuity Frameworkbasic living conditionsfood
• Tryptophan metabolism in trophoblast development and function: a scoping review of in vitro and ex vivo placental models.
  The current review aims to summarise the current in vitro and ex vivo evidence for the role of tryptophan and its metabolites in trophoblast function and placental development and to identify gaps in experimental research to inform future investigations.
  datacite Ione Halford Garcia, Norah Mary Elizabeth Fogarty, Hannah Ee Juen Yong 2026 置信度 0.66 Cell and Developmental BiologyChemicals and DrugsFemale Urogenital Diseases and Pregnancy ComplicationsDiseasesMedicine and Health Sciences
• Environmental Impact Assessment (SEC) ZO 3610
  T.Y.B.Sc. | Sem VI | ZO 3610 ZOOLOGY Environmental Impact Assessment (SEC) It’s a great pleasure for us to present this book Environmental Impact Assessment, Skill Enhancement Course [SEC] (Zo-3610, Semester VI) for T. Y. B. Sc. Zoology and other Students thos…
  datacite Jawale, Chetan 2022 置信度 0.66 Environmental Impact AssessmentPollution preventionSustainable development
• Environmental Impact Assessment (SEC) ZO 3610
  T.Y.B.Sc. | Sem VI | ZO 3610 ZOOLOGY Environmental Impact Assessment (SEC) It’s a great pleasure for us to present this book Environmental Impact Assessment, Skill Enhancement Course [SEC] (Zo-3610, Semester VI) for T. Y. B. Sc. Zoology and other Students thos…
  datacite Jawale, Chetan 2022 置信度 0.66 Environmental Impact AssessmentPollution preventionSustainable development
• Evidence Resolution, Formulation Identifiability, and Predictive Transportability of Microbiome-Targeted Randomized Trials in MASLD: Retrospective Protocol and Analytical-Framework Registration
  This registration provides a time-stamped retrospective record of the protocol evolution, evidence-governance rules, analytical gates, and frozen statistical framework for a systematic evidence-structure analysis of microbiome-targeted randomized trials in met…
  datacite BIAO GAO 2026 置信度 0.66 Medicine and Health SciencesLife SciencesMASLD NAFLD gut microbiome probiotics prebiotics synbiotics systematic review evidence synthesis formulation-level evidence component identifiability structural identifiability Bayesian meta-analysis prediction interval treatment heterogeneity
• Technical Specifications, Operational Workflows, and Methodological Frameworks of Gemini-LifeScientist
  ⚡ TL;DR: This document defines the rigorous evidentiary hierarchies, data integration standards, and analytical pipelines governing the Gemini-LifeScientist expert system for high-fidelity biomedical research. Abstract: This document outlines the rigorous tech…
  datacite Gemini-LifeScientist 2026 置信度 0.66 biomedicineevidence synthesisAI expert systemscientific researchpharmacokinetics
• Technical Specifications, Operational Workflows, and Methodological Frameworks of Gemini-LifeScientist
  ⚡ TL;DR: This document defines the rigorous evidentiary hierarchies, data integration standards, and analytical pipelines governing the Gemini-LifeScientist expert system for high-fidelity biomedical research. Abstract: This document outlines the rigorous tech…
  datacite Gemini-LifeScientist 2026 置信度 0.66 biomedicineevidence synthesisAI expert systemscientific researchpharmacokinetics
• Comparative numerical and experimental evaluation of 3D-printed micromixers for biotechnological applications.
  Micromixers are essential in microfluidic-based biotechnology and diagnostics, where reproducible reactions and rapid mass transfer are crucial. Although many geometries exist, consistent comparison across dimensions, fabrication methods, and evaluation techni…
  pubmed Mengele M, Zürn J, Lochner T, Weiß U 等 2026 Aug 28 置信度 0.82
• Temperature mediates variation in avian sensitivity to forest cover.
  Emerging evidence shows that responses to deforestation can differ both across species and among populations of the same species. The reasons underlying these complex patterns are unclear, and this lack of clarity is a barrier to accurate monitoring and predic…
  pubmed Granville NR, Williams JJ, Groner VP, Barlow J 等 2026 Aug 28 置信度 0.82
• A new core-genome MLST approach for Chlamydia trachomatis genomic surveillance and research.
  Chlamydia trachomatis causes common sexually transmitted infections. The use of whole-genome sequencing for its classification and surveillance is limited due to technical challenges and the lack of standardized typing frameworks. In particular, core-genome mu…
  pubmed Lodhia Z, Mixão V, Isidro J, Ferreira R 等 2026 Aug 27 置信度 0.82
• Learning precise segmentation of neurofibrillary tangles from rapid manual point annotations.
  Accumulation of abnormal tau protein into neurofibrillary tangles (NFTs) is a pathologic hallmark of Alzheimer disease (AD). Accurate detection of NFTs in tissue samples can reveal relationships with clinical, demographic, and genetic features through deep phe…
  pubmed Ghandian S, Albarghouthi L, Nava K, Sharma SRR 等 2026 Aug 28 置信度 0.82
• Clarity and inclusivity as precursors to translating yoga health evidence: a diverse cross-sectional study on barriers, facilitators, and associations of yoga.
  Translating evidence-based interventions (EBIs) to advance health behaviors and well-being takes 15-17 years. This translational gap is lengthened for specific EBI and populations, such as yoga for people of color, with higher weight, or who live in rural area…
  pubmed Frazier MC, Frick BJ, Stauffer LH, Osborn TM 等 2026 Jan 7 置信度 0.82
• Total moderate-to-vigorous physical activity across the adult life course and the risk of invasive ovarian cancer.
  Previous research on moderate-to-vigorous physical activity (MVPA) and ovarian cancer risk have shown inconsistent results. Most studies measured recreational MVPA once during late adulthood, which does not consider the way in which timing may differently infl…
  pubmed Ritonja JA, Madathil S, Nicolau B, Leung L 等 2026 Aug 18 置信度 0.82
• Arthroscopy of femoroacetabular impingement and osteoarthritis: a systematic review.
  Although studies suggested an association between patient factors and various outcome measures in the surgical management of femoroacetabular impingement (FAI), there is a lack of consistent evidence of the influence of osteoarthritis (OA) in patients with FAI…
  pubmed Migliorini F, Cocconi F, Bardazzi T, Koettnitz J 等 2026 Aug 28 置信度 0.82
• Retraction notice to "Mechanism of chromium-induced toxicity in lungs, liver, and kidney and their ameliorative agents" [Biomedicine & Pharmacotherapy 151 (2022) 113119].
  pubmed Chakraborty R, Renu K, Eladl MA, El-Sherbiny M 等 2026 Aug 28 置信度 0.82
• Echo-EU-Net: Lightweight Deep Learning for Fully Automated Left Ventricular Segmentation and Ejection Fraction Quantification in Transgastric Short-Axis View on Transesophageal Echocardiography.
  Deep learning-based automated analysis of transgastric short-axis view (TSV) transesophageal echocardiography (TEE) remains under-explored. In this study, we propose a deep learning-based method for fully automated left ventricular segmentation and ejection fr…
  pubmed Ling Y, Tian Y, Qin W, Leonov D 等 2026 Aug 28 置信度 0.82
• Corrigendum to "Targeting GSS-mediated glutathione synthesis: 6-Met induces oxidative stress dependent apoptosis via triggering mitochondrial bioenergetics metabolism crisis and mTOR suppression in glioblastoma" [Redox Biol. 96 (2026) 104334].
  pubmed Lin J, Zhou H, Ma N, Chen Y 等 2026 Aug 28 置信度 0.82
• Developing leadership through talk: how small group reflections can enhance leadership competence.
  Competency-based medical education in postgraduate medical education (PGME) prioritises developing holistic physicians, including leadership competence. The leadership competence encompasses self-management, working effectively in teams, considering organisati…
  pubmed Felsted IL, Meeuwissen SNE 2026 Aug 28 置信度 0.82
• TROP2 Expression in Bladder Transurethral Resection Specimens: Correlation With Histological Grade and Survival.
  TROP2 has become a therapeutic target in urothelial carcinoma following the approval of TROP2-directed antibody-drug conjugates (ADCs), yet its expression in transurethral resection (TURBT) material remains poorly characterized. This study aimed to evaluate TR…
  pubmed Gündoğar Ö, Bektaş S, Arslan B, Akbaş P 2026 Sep-Oct 置信度 0.82
• Colitis Ameliorates Murine Autoimmune Cholangitis Through Polarization of M2 Macrophages and Inhibition of CD8(+) T-Cells.
  Primary biliary cholangitis (PBC) is a form of chronic autoimmune cholangitis of enigmatic etiology and pathogenesis. While numerous studies indicate an association between inflammatory bowel disease (IBD) and PBC, the bidirectional impact on disease progressi…
  pubmed He M, Liu H, Zhang M, Liu B 等 2026 Sep-Oct 置信度 0.82
• Longitudinal Immunophenotypic Changes in Refractory Lupus Nephritis After B-cell Depletion: A 25-year Case Study.
  Long-term management of systemic lupus erythematosus (SLE) requires a persistent balance between intensive immunosuppression and the prevention of opportunistic infections. This is particularly challenging in patients with a multi-decade disease history and ev…
  pubmed Chen CC, Lu JW, Ho YJ, Lui SW 等 2026 Sep-Oct 置信度 0.82
• Composite Coating-driven Regulation of In Vivo Magnesium Degradation and Tissue Response.
  Magnesium-based alloys are promising materials for fabrication of bioresorbable medical devices. The application is limited by rapid degradation and associated adverse tissue responses. In this study, nanometer-thin composite polyelectrolyte/wax (PEM/W) coatin…
  pubmed Andreeva TD, Burkhardt K, Jung O, Stammkötter S 等 2026 Sep-Oct 置信度 0.82
• Unmasking a B-Cell Linkage Phenotype in Severe Acute Meningoencephalitis: A Case Report of IVIG and HydroBox-assisted Immunomodulatory Therapy.
  Severe acute meningoencephalitis is a life-threatening neurological condition frequently associated with excessive inflammation, immune dysregulation, and secondary immune dysfunction. Immune exhaustion and abnormal immune cell remodeling may contribute to per…
  pubmed Wu CL, Lu JW, Ho YJ, Wu MC 等 2026 Sep-Oct 置信度 0.82
• Plexiform Fibrohistiocytic Tumor: An Updated Review.
  Plexiform fibrohistiocytic tumor (PFHT) is a rare locally aggressive and rarely metastasizing mesenchymal neoplasm that most commonly arises in the upper extremities of children and young adults. It typically presents as a small, slow-growing, painless, dermal…
  pubmed Nishio J, Koga K, Aoki M 2026 Sep-Oct 置信度 0.82
• Dissociated FoxP3 Up-regulation With Functional Surface Marker Loss Defines a Convergent Treg Paradox Across Immunological Archetypes of IgA Nephropathy and IgA Vasculitis.
  Immunoglobulin A nephropathy (IgAN) and immunoglobulin A vasculitis (IgAV) exhibit remarkable clinical heterogeneity, yet its underlying immunological diversity remains poorly characterized. We investigated whether high-dimensional peripheral blood immunopheno…
  pubmed Fang PJ, Kuo PH, Lu JW, Ho YJ 等 2026 Sep-Oct 置信度 0.82
• Magnolol Potentiates Sorafenib-induced Apoptosis and Inhibits Metastatic Signaling in Renal Carcinoma.
  Sorafenib is a standard targeted therapy for renal cell carcinoma; however, resistance and limited efficacy remain clinical challenges. Magnolol, a bioactive compound derived from Magnolia officinalis, exhibits anti-cancer properties, and may enhance therapeut…
  pubmed Chang CC, Hung MY, Weng YS, Chang CM 等 2026 Sep-Oct 置信度 0.82
• Anti-gicerin Antibody Suppresses Early Pulmonary Metastatic Colonization of B16F10 Melanoma Cells.
  Adhesion of circulating melanoma cells to the pulmonary vascular bed is a critical early step in hematogenous metastasis. Gicerin is an immunoglobulin superfamily cell adhesion molecule that can mediate homophilic cell-cell adhesion. We examined whether giceri…
  pubmed Kirimura N, Ueno S, Yamazaki R, Tsukamoto Y 2026 Sep-Oct 置信度 0.82
• Inflammatory Myofibroblastic Tumor of the Urinary Bladder Presenting as a Radiological cT3 Mass: A Case Report and Narrative Review of 89 Cases.
  Inflammatory myofibroblastic tumor (IMT) of the urinary bladder is a rare mesenchymal neoplasm of intermediate malignancy that frequently mimics locally advanced urothelial carcinoma on imaging. The optimal surgical management when computed tomography suggests…
  pubmed Chen HX, Liu SL, Huang CP, Hsu YC 等 2026 Sep-Oct 置信度 0.82
• Salivary Metabolomics: A Pilot Study for Screening Biomarkers in Mild-to-moderate Periodontitis.
  This study aims to identify salivary metabolites that can discriminate patients with mild and moderate periodontitis from healthy controls through comprehensive metabolomic analyses using capillary electrophoresis-mass spectrometry (CE-MS).
  pubmed Edamatsu K, Ishikawa S, Sugimoto M, Okuyama N 等 2026 Sep-Oct 置信度 0.82
• Fecal microbiota transplantation versus vancomycin or fidaxomicin in Clostridioides difficile infection first episode and first recurrence: a study protocol for a randomised, controlled, open-label, multicentre phase III clinical trial.
  Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated diarrhoea in adults, with recurrence rates of 15%-25% after a first episode and up to 65% after multiple recurrences. Recurrent CDI leads to significant morbidity, diminished …
  pubmed Galpérine T, Erard V, Sommerstein R, Albricht WC 等 2026 Aug 28 置信度 0.82
• PREVENT 1, a nationwide Swedish infant cohort for longitudinal gut microbiome profiling and early-life health outcomes: cohort profile.
  PREVENT 1 is a nationwide, prospective Swedish infant cohort established to characterise gut microbiome development during the first 2 years of life and to relate microbial trajectories to feeding, infections, growth and everyday well-being. The study integrat…
  pubmed Orwa S, Vlajic M, Cavani E, Devall AE 等 2026 Aug 28 置信度 0.82
• Community-based paediatric eye care in low- and middle-income countries: bridging the gap between policy and practice.
  Childhood visual impairment and blindness remain major public health concerns in low- and middle-income countries (LMICs), despite a substantial proportion being preventable or treatable. Delayed diagnosis, inadequate access to eye care services, fragmented re…
  pubmed Tripathy D, Roy P, Nayak B, Taywade M 2026 Aug 28 置信度 0.82
• "Are you sexually active?": Unilateral informing patterns in communicating the sexual impact of prostate cancer treatment.
  Prostate cancer treatments can impact couples' sex lives; accordingly, the sexual impact of treatment is an important topic during clinical consultations. This study explores how the sexual impact of treatment is communicated to couples during consultations fo…
  pubmed Stewart SJ, Roberts L, Brindle LA 2026 Sep 置信度 0.82
• A telomere-to-telomere genome assembly of Medicago ruthenica enables QTL mapping and marker development for pod shattering resistance.
  pubmed Li Q, Wang M, Wang W, Gao J 等 2026 Aug 28 置信度 0.82
• Airway Lipid Mediators in Horses: Baseline Bronchoalveolar Lavage Fluid Profiles and Effects of EPA and DHA-rich Microalgae Oil Supplementation.
  We investigated how dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) affect airway inflammation, bronchoalveolar lavage fluid (BALF) lipid mediators and red blood cell fatty acids in horses. Inc…
  pubmed Vainio Kati ME, House Andrew H, Höglund Nina M, Hanna R 等 2026 Aug 28 置信度 0.82
• CRISPR-Cas12a cleavage-based fluorescence biosensor to detect arsenic content in rice grains from different regions of China.
  Nano-based sensors play a significant role in detection of heavy metals. Arsenic contaminated rice poses a serious health hazard. Nano-based rapid detection of arsenic (As 3+ ) in rice is essential to perform rapid detection. To resolve the above problem, we l…
  pubmed Chen J, He Y, Donglan Z, Shi J 等 2026 Aug 28 置信度 0.82
• Rheological modulation of egg white protein-based capillary suspensions via synergistic capillary bridging and chitosan-mediated hydrogen bonding.
  Capillary suspensions are ternary solid-liquid-liquid systems formed by introducing a secondary fluid into a suspension of solid particles in a bulk liquid. While previous studies have established the concept of polymer-enhanced capillary suspensions, systemat…
  pubmed Hou Y, Hu Y, Li Z, Zhang Y 等 2026 Aug 28 置信度 0.82
• Endocrine Disrupting Effects of Estrone on Male Siniperca chuatsi: From Gonadal Remodeling to Gene Regulation.
  Estrone (E1), a ubiquitous environmental estrogen, poses a potential threat to the reproductive health of aquatic organisms. To evaluate the inducing effect of E1 exposure on gonadal feminization in male Siniperca chuatsi, male fish were exposed to 0, 0.01, 0.…
  pubmed Chen K, Zhang Y, Li W, Yang H 等 2026 Aug 28 置信度 0.82
• Gut microbiota dysbiosis in spinal cord injuries: immune impairment and therapeutic potential of microbiome modulation.
  The gut microbiota plays a fundamental role maintaining homeostasis by regulating neuroglial maturation, immune function, and the production of gut derived metabolites (e.g short chain fatty acids and neurotransmitters), while also preventing pathogen coloniza…
  pubmed Ossandon-Pino N, Mardones L, Vidal PM, Nicole Ossandon-Pino 等 2026 置信度 0.82
• Dietary vitamin E alleviates ammonia-induced effects on survival, antioxidant and immune response of post-larval Pacific white shrimp.
  It remains unknown whether vitamin E (VE), a fat-soluble vitamin known for its potent antioxidant effects, alleviates the stress caused by ammonia-N exposure in post-larval Pacific white shrimp (Penaeus vannamei). Five isonitrogenous (crude protein: 32.5%) and…
  pubmed Ko D, Lee KJ 2026 Aug 28 置信度 0.82
• Nanobodies (Nbs) in virology and viral diseases: Applications in viral detection, neutralization, and therapy.
  Nanobodies (Nbs), also known as variable domains of camelid heavy-chain-only antibodies (VHHs), have emerged as promising biomolecules in antiviral diagnostics and therapeutics because of their small molecular size, high stability, strong antigen-binding affin…
  pubmed Mohebbi M, Monavari SH, Hadidi N, Safarnezhad Tameshkel F 等 2026 Aug 28 置信度 0.82
• Techno-economic analysis of farmer-scale biochar production from agricultural residues in the U.S. Corn Belt: A comparison of three low-cost kiln architectures.
  Decentralized, farmer-scale biochar production can valorize agricultural residues for soil amendment and carbon storage while avoiding the feedstock-transport burden of centralized pyrolysis. This study compared three low-capital, field-deployable kiln archite…
  pubmed Asare F, Gazo R, Mo J, Haviarova E 等 2026 Aug 28 置信度 0.82
• Joint Toxicant and Psychosocial Exposures and Health: A Scoping Review of Evidence and Analytic Approaches.
  Early life environmental toxicant exposure is associated with adverse physical and mental health, yet individual susceptibility varies. Psychosocial exposures, like socioeconomic disadvantage and stress, frequently co-occur with toxicant exposure and also infl…
  pubmed Stein SF, Halabicky OM, Giang C, Handal AJ 等 2026 Aug 28 置信度 0.82
• Proteomics reveals the mechanism by which sodium oleate decreases Escherichia coli susceptibility to gentamicin.
  The World Health Organization has listed antibiotic resistance as one of the top ten health threats. There is an urgent need to analyze the resistance mechanism to develop novel anti-infection strategies. Fatty acids have been reported to promote antibiotic re…
  pubmed Fan L, Wu J, Zhang Z, Cai L 等 2026 Aug 28 置信度 0.82
• Major Dietary Protein Sources during Pregnancy and Obesity Risk in Mothers and Offspring: A Prospective Cohort Study.
  Maternal protein intake during pregnancy may influence long-term obesity risk in mothers and offspring, but the role of specific dietary protein sources remains unclear.
  pubmed Zhang H, Zheng M, Halldórsson ÞI, Olsen SF 等 2026 Aug 28 置信度 0.82
• Metabolic engineering of Rhodococcus aromaticivorans RHA1 for muconic acid production from lignin.
  Lignin has potential as a sustainable feedstock to replace fossil fuels in chemical manufacturing. The coupling of chemical fractionation and biocatalysis has emerged as a promising technology to realize this potential. In this process, chemocatalytic fraction…
  pubmed Lalande AT, Robeck LD, Hofsommer DT, Lippuner LCL 等 2026 Aug 28 置信度 0.82
• Revealing Alkali Ion Modulation on the Nucleation Phase of Highly Concentrated α-Synuclein Probed by Thioflavin T Lasing Spectroscopy.
  Abstract
Early nucleation events during α-synuclein (αS) aggregation remain challenging to investigate because conventional fluorescence assays lose sensitivity in highly concentrated biomolecular environments. Here, we present Thioflavin T…
  pubmed Struniawski K, Jałonicka E, Konopka A, Szwachta G 等 2026 Aug 28 置信度 0.82
• Community-acquired pneumonia in adults: acute and long-term complications.
  Annually, community-acquired pneumonia (CAP) affects millions of individuals worldwide, resulting in more than 200 000 hospital admissions in England alone. CAP is a major cause of morbidity and mortality. Previous studies have explored the causes, risk…
  pubmed Chalmers J, Bansal K, Scott R, Hamilton F 等 2026 Aug 28 置信度 0.82
• Functional versatility of synergid cells in plant reproduction.
  In flowering plants (angiosperms), the Polygonum-type embryo sac accounts for approximately 70% of the female gametophytes. It contains three antipodal cells, one central cell, one egg cell, and two synergid cells. Apart from the female gamete cells, the syner…
  pubmed Li L, Lin H, Qu LJ, Zhong S 2026 置信度 0.82
• Human nuclear ribomes reveal DNA-embedded ribonucleotides as epigenetic modulators of transcription-associated DNA supercoiling.
  Ribonucleoside monophosphates (rNMPs) are the most abundant non-canonical nucleotides in DNA, yet their distribution and function in the human nuclear genome remain unclear. We present high-resolution maps of ∼1 million rNMPs per genome across diverse h…
  pubmed Kundnani DL, Lee Y, Yang T, Warner TP 等 2026 Aug 28 置信度 0.82
• Intragenomic homologs with distinct phase behaviors broaden the range of cellular stress responses.
  Intragenomic homologs are widespread, but their physiological roles are often masked by redundancy. Histone-like nucleoid structuring protein (H-NS), a nucleoid-associated protein in Gram-negative bacteria, typically coexists with homologs like StpA, whose fun…
  pubmed Guan J, Sahoo BR, Brant TS, Mahadevan P 等 2026 Aug 28 置信度 0.82
• Inhibition of the lipocalin-2-phosphatidylserine axis restores natural killer cell immune surveillance.
  Lipid metabolic reprogramming can facilitate immune escape by promoting a suppressive phenotype in tumor-infiltrating immune cells, although this process remains poorly understood. Here, we identify the lipoprotein, Lipocalin-2 (LCN2), as an essential factor d…
  pubmed Qin J, Hu X, Wang L, Cai Y 等 2026 Aug 28 置信度 0.82
• Directional disparity between oysters and mud snails in modulating marine carbon sequestration.
  Amplified greenhouse effects underscore the importance of coastal shellfish to uptake and sequester atmospheric CO 2 via the biological carbon pump. With continuous allochthonous nutrient input, the filter-feeding oysters enhance the marine carbon sequestratio…
  pubmed Zhang Z, Dong X, Lei YJ, Guo ZY 等 2026 Aug 28 置信度 0.82
• Thermal stratification onset increases phytoplankton resource use efficiency by promoting photosynthetic activity in a subtropical reservoir.
  Phytoplankton resource use efficiency (RUE), expressed as biomass per unit nutrient (RUE TN , RUE TP ) integrates phytoplankton productivity and nutrient exploitation in aquatic ecosystems, yet how thermal stratification affects RUE TN , RUE TP , and the under…
  pubmed Luo A, Chen H, Jin L, Jeppesen E 等 2026 Aug 28 置信度 0.82
• Intron retention as a hub for splicing regulation in plant environmental adaptation and developmental programming.
  Alternative splicing (AS) greatly expands transcriptome and proteome diversity in eukaryotes. Intron retention (IR) is the predominant AS type in plants, with critical roles in environmental adaptation and developmental control. Long viewed as splicing noise, …
  pubmed Xu W, Wang M, Liu L 2026 Aug 26 置信度 0.82
• Mechanistic insights into high-intensity ultrasound-induced debittering and umami-enhancing of Antarctic krill peptides during ultrasound-assisted flavourzyme hydrolysis: Integrating E-tongue, multi-spectroscopy, and label-free peptidomics.
  The bitterness of protein hydrolysates negatively affects the utilization of protein-rich by-products from Antarctic krill after oil extraction. The debittering and umami-enhancing effects as well as the underlying mechanisms of high-intensity ultrasound on An…
  pubmed Liu H, Chen J, Xie R, Hu J 等 2026 Aug 28 置信度 0.82
• In vivo and in vitro assessment of absorption and disposition kinetics of bis[2-(perfluorohexyl)ethyl] phosphate in rats: food effect, physiologically-based modeling, and human exposure estimation.
  Bis[2-(perfluorohexyl)ethyl] phosphate (6:2 diPAP) is a widely used per- and poly-fluoroalkyl substance of toxicological concern considering its environmental persistence and potential for human exposure. To establish a mechanistic basis for evaluating interna…
  pubmed Kim M, Yang E, Chung SJ, Lee W 等 2026 Aug 20 置信度 0.82
• In-Situ engineering of hierarchical ZIF@HOF heterostructures for efficient antibiotic degradation: Mechanistic insights from experimental and DFT studies.
  The relentless release of pharmaceutical antibiotics into water bodies demands robust and reusable photocatalysts. Herein, a hierarchical ZIF-67@Co-HOF-x heterostructure is synthesized through the in-situ growth of ZIF-67 onto a pre-formed cobalt-based hydroge…
  pubmed Ahmad A, Akram N, Tufail MK, Yu B 等 2026 Aug 24 置信度 0.82
• Multimodal computational framework resolves B cell maturation in autoimmunity and ageing.
  Identification of the origin of pathogenic immune cells is crucial for therapeutic interventions and diagnosis but pseudotime methods struggle to trace immune cells accurately. Current trajectory inference methods for B cell development and response in health …
  pubmed Lou H, Zhang M, Zhang B, Lu Q 等 2026 置信度 0.82
• A national cross-sectional survey of the bullying and harassment experiences among radiographers in the United Kingdom.
  Workplace bullying and harassment (WBH) are persistent psychosocial hazards in healthcare, linked to psychological harm, increased staff turnover, and compromised patient safety. Although the profession has been extensively studied in nursing and medicine, evi…
  pubmed Ollawa CU, Iweka E, Ezenwuba BN, Eteng R 等 2026 Aug 28 置信度 0.82
• DIY global health: Informality, privilege and ideologies that drive short-term medical missions.
  This article draws attention to Do-It-Yourself (DIY) global health, a concept that highlights global health activities that are unmoored from organizational structures and accountabilities typically constraining global health work. I use this conceptual orient…
  pubmed Berry NS 2026 Aug 26 置信度 0.82
• Liver miRNome is modulated by nutrient restriction in early lactation cows challenged with intramammary lipopolysaccharide.
  Dairy cows are vulnerable to health problems during the transition period, associated with a negative energy balance (NEB). MicroRNAs are known to influence many biological processes including inflammation. This study aimed to evaluate the effects of nutrient …
  pubmed Faulconnier Y, Pires JAA, Ye T, Pawlowski K 等 2026 Aug 25 置信度 0.82
• Trauma is different: Redefining abnormal Functional Status Scale values in injured children.
  The Functional Status Scale has been proposed for assessing functional outcomes after pediatric injury. The Functional Status Scale was developed in critically ill children with a score of 6 defined as normal and Functional Status Scale ≥8 as "abnormal.…
  pubmed Castro MR, Shui AM, Lee C, Niedzwecki C 等 2026 Aug 3 置信度 0.82
• CaMACPF1 and CaMACPF6 positively regulate hypoxia tolerance through modulating jasmonate and auxin metabolic pathways.
  Submergence and flooding impose severe crop losses through hypoxic stress. The Membrane Attack Complex/Perforin (MACPF) superfamily proteins function as pore-forming effectors in development and immunity across eukaryotic organisms, yet their role in plant hyp…
  pubmed Guo Y, Ma S, Yu Y, Li Z 等 2026 Aug 26 置信度 0.82
• Heparin formulation and thromboprophylaxis intensity in critically ill patients: Results from the ESICM UNITE registry.
  Decisions regarding heparin formulation and thromboprophylaxis intensity are central to intensive care practice, yet the optimal strategy remains uncertain. We evaluated associations between anticoagulation strategies and three primary outcomes - life-threaten…
  pubmed Lavinio A, Rocheteau E, Antonelli M, Morris AC 等 2026 Aug 25 置信度 0.82
• Macrozoobenthic diversity of eutrophication hotspots under anthropogenic pressures in the southern Black Sea: Interactions between environmental factors and community structure.
  The Black Sea is among the marine systems most affected by eutrophication, but benthic responses along its southern shelf remain poorly documented compared with the intensively studied northwestern shelf. Soft-bottom assemblages at ten stations off the Sakarya…
  pubmed Kurt G, Tan İ, Çağlar S, Atabay H 等 2026 Aug 28 置信度 0.82
• Beyond conventional mobility tests: Validity and reliability of the dubousset functional test in individuals with multiple sclerosis.
  Multiple sclerosis (MS) is characterized by neuroinflammation and neurodegeneration, leading to impairments in balance, mobility, and functional performance. Current clinical assessments predominantly evaluate isolated aspects of motor function and often fail …
  pubmed Abakay H, Yetkin MF, Baykan Çopuroğlu Ö, Yinanç SB 等 2026 Aug 20 置信度 0.82
• Limits and frontiers of microbial phenotype measurements.
  Over the past two decades, microbiology has gained revolutionary new tools for observing microbial life. Yet measuring microbial phenotypes and interpreting those measurements remains a fundamental challenge. Measurement is confounded by phenotypes that are se…
  pubmed Caro TA, Schaible GA, Cremer J, Haruta S 等 2026 Aug 27 置信度 0.82
• From noticing suffering to preserving connection: Memory-making as a nursing response in the PICU - Letter on Broden Arciprete et al.
  pubmed Lilitwat W 2026 Aug 28 置信度 0.82
• Global downstream BMP15 pathway analysis in human ovarian granulosa cells reveals novel genetic variations associated with primary ovarian insufficiency.
  Primary ovarian insufficiency (POI) is a fertility disorder with a well-established genetic component, but many cases still remain idiopathic. Approximately 1.5-12% of patients with POI can carry a variant in the BMP15 gene, depending on the population and the…
  pubmed Rossetti R, Fornili M, Moleri S, Ferrari I 等 2026 Aug 26 置信度 0.82
• Biomimetic engineering of a fortified ice composite with enhanced mechanical properties.
  This work presents BioPykrete, a high-performance sustainable bio-composite engineered from ice, cellulose nanocrystals (CNC), and a custom chimeric protein designed to facilitate interfacial adhesion. By genetically fusing the ice-binding protein AFPIII with …
  pubmed Adar C, Baron Y, Rofman B, Bar Dolev M 等 2026 Aug 2 置信度 0.82
• Rehabilitation prescription tools in adult critical care: A scoping review.
  Rehabilitation for critically ill patients aims to reduce immobility and intensive care unit (ICU) acquired weakness. However, evidence regarding effectiveness remains inconclusive. Prescription tools enabling individualised rehabilitation may improve outcomes…
  pubmed Flowers E, Allum L, Saha S, Law E 等 2026 Aug 28 置信度 0.82
• Global Leadership Initiative on Indications to Nutritional Therapy and Support (GLINTS): A consensus report from the global clinical nutrition community.
  Providing clear guidance for nutritional interventions is a precondition for the fight against the consequences of (risk of) malnutrition/undernutrition. Therefore, a group of international experts representing major global and regional clinical nutrition soci…
  pubmed Klek S, Barazzoni R, Blaauw R, Burgos R 等 2026 Aug 26 置信度 0.82
• Impact of saturated fat absorption on serum low density lipoprotein-cholesterol response to the replacement of saturated with unsaturated fats in healthy males. The 'Reading, Imperial, Surrey, Saturated fat Cholesterol Intervention-2 (RISSCI-2)' non-randomised sequential dietary intervention study.
  Serum low-density lipoprotein (LDL)-cholesterol varies in response to the isonergetic replacement of saturated (SFA) with unsaturated fats (UFA), as reported in our previous screening study, 'Reading, Imperial, Surrey, Saturated fat Cholesterol Intervention-1'…
  pubmed Fielding BA, Koutsos A, Antoni R, Ozen E 等 2026 Aug 24 置信度 0.82
• Organ-specific phytochemical profiling and biological activities of Asphodelus aestivus L.: Integrating in vitro assays, DFT analysis, molecular docking, and network pharmacology.
  Asphodelus aestivus L. is a traditionally used medicinal plant with significant therapeutic and nutritional value. This study investigated the phytochemical composition, antioxidant activity, phenolic and flavonoid contents, cytotoxic effects, and nutritional …
  pubmed Güçlü G, Özkan HN, Kapancik S, Kaya S 等 2026 Aug 25 置信度 0.82
• Incidence of Dementia in Older Adults Hospitalized With Acute Coronary Syndrome: Insights From KP-Brain-Heart Health Study.
  Cognitive decline has been reported after coronary artery revascularization, but whether it reflects procedure-specific effects or the burden of underlying vascular disease remains uncertain.
  pubmed Krishnaswami A, Jain A, Gilsanz P, Canio W 等 2026 Aug 28 置信度 0.82
• A systematic review of state loneliness in daily life using intensive longitudinal methods.
  Loneliness, including its associations with mental health, is recognised as a major global public health concern. While much research has focused on chronic loneliness, state loneliness - experienced in moment-to-moment contexts - remains underexplored. This g…
  pubmed Xiao Z, Ozdemir E, Long E, Kwong A 等 2026 置信度 0.82
• Ribonucleotide Reductase Inhibition Triggers Ferroptosis in Genetically Defined Subsets of Non-Small Cell Lung Cancer.
  Non-small-cell lung cancer (NSCLC) is responsible for the majority of cancer-related mortality worldwide. Lung adenocarcinoma (LUAD) is the most common NSCLC subtype. Despite advances in targeted therapies, treatment resistance remains a critical challenge. Ri…
  pubmed Sen U, Natour D, Chakraborty S, Gobbini E 等 2026 Aug 28 置信度 0.82
• Human Cytomegalovirus Genetic Diversity, Clinical Relevance, and Emerging Insights.
  Human cytomegalovirus (HCMV) is a globally prevalent virus that poses a significant public health concern, especially for newborns and immunocompromised patients, causing a wide range of infections. Clinical outcomes associated with HCMV infection include cong…
  pubmed AlQahtani HY, Aleanizy FS, Alqahtani FY 2026 Sep 置信度 0.82
• Rice stripe virus exploits the miR159a.2-OsGTL1 module to manipulate growth-defense trade-offs.
  Balancing growth and defense is critical for plant fitness and crop productivity, yet how viruses manipulate this trade-off remains unclear. Here, we identified the trihelix transcription factor Oryza sativa GT2-like 1 (OsGTL1) as a central regulator of the gr…
  pubmed Liu Q, Wang Q, Zhou W, Wang W 等 2026 Aug 4 置信度 0.82