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• Index
  crossref 2025-01-31T18:07:49Z 置信度 0.70
• SBiRM: future innovation and practice in Personalized and Precision Reproductive Medicine
  crossref Stephen A. Krawetz 2025-01-24T12:51:22Z 置信度 0.70
• ACP‐DPE: A Dual‐Channel Deep Learning Model for Anticancer Peptide Prediction
  ABSTRACT Cancer is a serious and complex disease caused by uncontrolled cell growth and is becoming one of the leading causes of death worldwide. Anticancer peptides (ACPs), as a bioactive peptide with lower toxicity, emerge as a promising means of effectively…
  crossref Guohua Huang, Yujie Cao, Qi Dai, Weihong Chen 2025-03-23T11:40:46Z 置信度 0.70
• systems biology
  Citation: 'systems biology' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12731 • License: The IUPAC Gold Book is licensed under Creative Commons …
  crossref 2024-11-08T13:33:04Z 置信度 0.70
• Kinetics and dynamics of biological systems
  crossref Elham Amjad, Babak Sokouti 2024-11-08T03:46:36Z 置信度 0.70
• Understanding Robustness in Biological Systems
  crossref 2025-12-11T07:08:36Z 置信度 0.70
• Machine Learning‐Assisted Plant Systems Biology
  crossref Haragopal Dutta, Suman Dutta, Sudhir Kumar 2025-11-14T20:08:44Z 置信度 0.70
• NMR Studies of Biomolecular Systems
  crossref Lewis E. Kay, Remco Sprangers 2025-10-15T07:10:05Z 置信度 0.70
• Developing an Evaluation Framework for Infectious Disease Modelling-to-Policy Pathways: A Qualitative Study Across Five Continents
  preprints 2026 置信度 0.74
• Cross-Species Aging Knowledge Integration into Agentic AI Platform Uncovers Conserved Mechanisms
  Abstract Aging research has been advanced largely through the use of model organisms, where short lifespans and genetic tractability enable the systematic discovery of molecular pathways influencing longevity and age-related decline. However, knowledge about a…
  preprints 2026 置信度 0.74
• Harnessing Genomic and Bioinformatics for Surveillance of Pathogens in Africa: A Scoping Review of Existing Training and Gaps in Training
  preprints 2025 置信度 0.74
• A Global Genomic Resource for Outcrossing <i>Arabidopsis lyrata</i> and <i>Arabidopsis arenosa</i>
  preprints 2026 置信度 0.74
• An Expanded Repertoire of tRNA Sources for Cell-Free Protein Synthesis
  preprints 2025 置信度 0.74
• CellTypeAI: Automated cell identification for scRNA-seq using local generative-AI
  Single-cell RNA sequencing (scRNA-seq) cell annotation techniques rely on the matching of known defining marker genes to a given cell population. However, these methods may lack robustness to dynamic fluctuations in cell marker expression between patients, sam…
  preprints 2026 置信度 0.74
• Can AlphaFold3 predict unseen amyloid polymorphs?
  preprints 2025 置信度 0.74
• GALLANT: A Scalable Computational Platform for Microbial Consortium Interaction and Population Heterogeneity Analysis
  preprints 2025 置信度 0.74
• Engineering protein expression dynamics with Tet-ON and dTAG degron systems: from precise control to oscillations
  preprints 2025 置信度 0.74
• AlphaFold Database expands to proteome-scale quaternary structures
  Protein function is governed by molecular interactions, yet structural coverage of these interactions remains sparse. The AlphaFold Protein Structure Database (AFDB) transformed access to accurate monomeric protein structures at scale. Here, we expand the AFDB…
  preprints 2026 置信度 0.74
• Emergence and antigenic characterisation of influenza A(H3N2) viruses with hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season
  preprints 2026 置信度 0.74
• Early nervous system development in the chaetognath <i>Spadella cephaloptera</i> exhibits conserved bilaterian patterning features
  preprints 2026 置信度 0.74
• Genomic diversity and functional potential of facultative bacterial symbionts across scale insects
  preprints 2025 置信度 0.74
• Systematic Review of Over A Century of Global Bioscience Research
  preprints 2025 置信度 0.74
• Adapting the OpenFlexure Microscope for Affordable Live-Cell Imaging
  preprints 2026 置信度 0.74
• Sequence-level vocal convergence in common marmosets
  preprints 2026 置信度 0.74
• Maximum entropy networks predict fluctuations and stability of food web energetics
  preprints 2026 置信度 0.74
• Design and deployment of a regulation-compliant infrared heating system for UK field trials
  preprints 2026 置信度 0.74
• <i>Plasmodium falciparum</i> Research in Africa from 2000 to 2024: A Systematic Review and Bibliometric Visualisation
  preprints 2025 置信度 0.74
• Rooftop and Surface Garden Soils in Bangladesh Harbor Diverse Resistome Profiles
  preprints 2026 置信度 0.74
• Conserved lifestyle-associated chromosome architectures across mammalian symbionts
  preprints 2026 置信度 0.74
• Evolutionary persistence of a highly prevalent multicopy mitochondrial-derived nuclear insertion (Mega-NUMT) in Neotropical Drosophila flies
  Although strict maternal transmission of mitochondria is a general feature of animals for ensuring homogeneity in mitochondrial DNA (mtDNA) across generations, exceptions were reported in the recent past. For example, some extremely rare but spectacular cases …
  preprints 2026 置信度 0.74
• Spheroid culture remodels mitosis and the proteome in tumor cells
  preprints 2026 置信度 0.74
• Evolutionarily conserved transcriptional regulators control monoaminergic neuron development
  To what extent conserved developmental programs specify homologous cell types is a central question in biology. Here, we address this by focusing on reconstructing monoaminergic neuron development in Drosophila melanogaster embryo using time- resolved single-c…
  preprints 2025 置信度 0.74
• RNAseK is vital for epithelial proton pump activity in Drosophila melanogaster
  preprints 2026 置信度 0.74
• Classifier architecture and data preprocessing jointly shape accelerometer-based behavioural inference
  preprints 2026 置信度 0.74
• Localization-dependent activation of the DEAD-box ATPase Vasa by eLOTUS domains
  ABSTRACT DEAD-box RNA helicases remodel RNA structures in many cellular pathways, yet how their activity is spatially controlled in cells remains poorly understood. The Drosophila germline helicase Vasa functions in ovaries only when localized to cytoplasmic g…
  preprints 2026 置信度 0.74
• Magnitude of biome shifts over the last 21,000 years reveals the impact of seasonality and intense warming on future vegetation
  preprints 2026 置信度 0.74
• SpliceUp: Predicting <i>SF3B1</i> mutations in individual cells via aberrant splice site activation from scRNA-seq data
  preprints 2025 置信度 0.74
• The Evolutionary Dynamics and Regional Spread of Mpox in Africa: Insights from Multi-country Genomic Surveillance
  preprints 2026 置信度 0.74
• MorphoLearn: A morphology-driven workflow to decipher 3D electron microscopy segmentation in diatoms
  Three-dimensional electron microscopy (3D EM) enables the quantitative analysis of cellular ultrastructure. However, large-scale segmentation of whole-cell volumes poses a significant challenge, especially in biologically diverse systems. Unlike medical and an…
  preprints 2026 置信度 0.74
• Cell phenotypes in the biomedical literature: a systematic analysis and text mining corpus
  The variety of cell phenotypes identified by single-cell technologies is rapidly expanding, yet this knowledge is dispersed across the scientific literature and incompletely represented in structured resources. We present the CellLink corpus, a manually annota…
  preprints 2026 置信度 0.74
• A Biologically Constrained Continuous-Time Framework for Long-Horizon Cognition Forecasting in Alzheimer’s Disease
  Accurate long-term forecasting of cognitive trajectories across the Alzheimer’s disease continuum is essential for early intervention, personalized prognosis, patient stratification, and clinical trial enrichment. Despite the promising predictive performance o…
  preprints 2026 置信度 0.74
• Open Benchmarking for Cell-Based Multiscale Models: Lessons from a Community Initiative
  The emergence of virtual human twins (VHT) in biomedical research has sparked interest in multiscale in silico modelling frameworks, particularly in their application bridging cellular to tissue levels. Among the diverse array of multiscale modelling tools, of…
  preprints 2025 置信度 0.74
• Changing seasonality and phenology mediate the effects of migration across meta-ecosystems
  preprints 2025 置信度 0.74
• Multi-fiber array-based photometry system for multi-regional functional mapping in the mouse brain
  Mesoscopic functional brain mapping is essential to better understanding of various brain functions and dysfunctions. However, accessing distributed neural circuits in mammalian brain regions remains a significant challenge. While fiber photometry is a versati…
  preprints 2025 置信度 0.74
• Purification of post-transcriptionally modified tRNAs for enhanced cell-free translation systems
  preprints 2025 置信度 0.74
• Tardigrade-Derived Strategy for Low-Cost Storage of Cell-Free Expression Lysates
  Cell-free expression systems (CFES) are increasingly used alongside conventional biotechnological approaches to accelerate early-stage prototyping and are particularly valuable in point-of-use settings. However, their broader adoption remains limited by time- …
  preprints 2026 置信度 0.74
• Low-barrier hydrogen-bond powers long-range radical transfer in the metal-free ribonucleotide reductase
  preprints 2026 置信度 0.74
• Structure-Function Dynamics in Healthy Cognitive Aging: A Graph Signal Processing Approach
  Network neuroscience has significantly advanced our understanding of how structural and functional connectivity evolve during healthy neurocognitive aging. Yet, integrative studies linking structural and functional brain organization with cognitive performance…
  preprints 2025 置信度 0.74
• An Aggregation Prone Region (APR) in talin controls talin self-interactions to regulate integrin adhesion complex dynamics
  The tight regulation of the integrin family of extracellular matrix (ECM) receptors is essential for the coordination of most cellular processes. Talin regulates integrin function by binding to the cytoplasmic tail of the integrin beta subunit. Two integrin-bi…
  preprints 2026 置信度 0.74
• Mapping the evolutionary path towards multi-drug resistance in the pandemic <i>Escherichia coli</i> ST131 lineage
  Escherichia coli sequence type (ST) 131 is the most widely studied genetic lineage of the species to date, originally identified in the early 2000s as an increasingly common cause of human urinary tract and bloodstream infections worldwide. This lineage is sub…
  preprints 2025 置信度 0.74
• Longevity Technology Transfer: From Laboratory to Marketplace
  preprints 2025 置信度 0.74
• A graphical approach of the interplay of eco-evolutionary dynamics and coexistence
  preprints 2026 置信度 0.74
• MALDI-TOF mass spectrometry and proteomics as phenotypic screening tools for anti-inflammatory drugs
  preprints 2025 置信度 0.74
• The Hidden Biology of Wellbeing: A Multi-Omics Analysis Across Genomic, Epigenomic, and Transcriptomic Layers
  Biological systems are composed of multiple molecular layers, including the genome, epigenome, transcriptome, and metabolome. These layers are interconnected and interact, but are often studied independently. Multi-omics approaches aim to integrate these layer…
  preprints 2025 置信度 0.74
• TRPM2 couples cell-autonomous type-I interferon signaling to pigmentation homeostasis
  preprints 2026 置信度 0.74
• Depletion and replacement of tissue resident macrophages in mice with germ-line deletion of a conserved enhancer in the <i>Csf1r</i> locus
  preprints 2026 置信度 0.74
• Fundamental limits on patterning by Turing-like reaction-diffusion mechanisms
  preprints 2025 置信度 0.74
• Chromosome Size as a Robust Predictor of Recombination Rate: Insights from Holocentric and Monocentric Systems
  preprints 2025 置信度 0.74
• From sample to insight: Onsite training and implementing mobile environmental surveillance in sub-Saharan Africa
  Environmental surveillance for human pathogen detection is crucial for safeguarding public health; however, traditional approaches are often time-consuming, equipment-intensive and workflow-complex, delaying actionable public-health decision-making. The integr…
  preprints 2026 置信度 0.74
• A synthetic cell phage cycle
  preprints 2025 置信度 0.74
• DySTrack: a modular smart microscopy tool for live tracking of dynamic samples on modern commercial microscopes
  preprints 2025 置信度 0.74
• Highly repeatable phenotypic consequences of whole-genome duplication in <i>Spirodela polyrhiza</i>
  preprints 2026 置信度 0.74
• Adhesive implant interfaces prevent fibrosis by disrupting mechanobiological feedback
  preprints 2025 置信度 0.74
• Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
  C-type lectins (CTLs) play key roles in innate immunity and microbial carbohydrate recognition. In the disease vector mosquito Aedes aegypti , the CTLD-S family comprises 34 soluble CTLs whose members are implicated in flavivirus dissemination and microbial ho…
  preprints 2026 置信度 0.74
• MATRIX: Rapid Quantification of Total and Active Microbial Cells with Single-Cell Phenotypes for Environmental Microbiomes
  Quantifying the abundance and activity of bacteria within populations and communities is fundamental to systems microbiology and microbiome research. Yet direct microscopic cell counting remains low-throughput, labor-intensive, and prone to user variability, l…
  preprints 2026 置信度 0.74
• Roots of Wheat and Rice maintain Gravitropic Setpoint Angles
  preprints 2026 置信度 0.74
• A root symbiont rewires tomato polyamine network to enhance herbivore resistance
  preprints 2026 置信度 0.74
• Ovothiol A mediates singlet oxygen resistance and acclimation in Chlamydomonas
  preprints 2026 置信度 0.74
• Bogong moths navigate using a light-dependent geomagnetic inclination compass
  Abstract Bogong moths (Agrotis infusa) migrate biannually up to 1,000 km between their breeding areas and geographically restricted aestivation sites in the Australian Alps 1,2 . These moths navigate towards their distant goal using the stars as a compass 3 bu…
  preprints 2026 置信度 0.74
• AI-driven biological clocks of cardiac aging: Should we integrate ECG, metabolomic, and epigenetic signatures?
  Abstract Background Cardiovascular diseases remain the leading cause of death globally, with age as the primary risk factor. Unlike chronological age, biological age aims to capture age-related physiological changes and may better predict health outcomes and d…
  preprints 2026 置信度 0.74
• Democratised single cell proteomics uncovers tumor associated macrophage signature in CYLD cutaneous syndrome skin tumors
  preprints 2026 置信度 0.74
• Selective Auditory Attention Decoding with a Two-Node Wireless EEG Sensor Network
  preprints 2026 置信度 0.74
• Data leakage and measurement error inflate the apparent predictability of overyielding from plant traits
  preprints 2026 置信度 0.74
• BCG vaccination attenuates Schistosoma mansoni-associated rural–urban immune variation
  Abstract Helminth-driven immunomodulation contributes to immune heterogeneity in tropical environments. Whether it can be reversed by BCG revaccination, an inducer of trained immunity, remains unknown. We applied high-dimensional mass cytometry to profile immu…
  preprints 2026 置信度 0.74
• Eukaryotic recombinases duplicated after divergence from known asgardarchaeal RadA: implications for the evolution of sex during eukaryogenesis
  preprints 2025 置信度 0.74
• Animal collocation analysis 2.0: improving statistical inference and applications for cohort comparisons
  preprints 2026 置信度 0.74
• Asgard archaeal origin of microtubules
  ABSTRACT Eukaryotic cells change their shapes, actively segregate their DNA and contain membrane networks, facilitated by a complex cytoskeleton containing actin filaments, microtubules made from tubulin, and other components. These filaments have ancient evol…
  preprints 2026 置信度 0.74
• Oscillatory traveling waves during visual entrainment in autistic and neurotypical adults
  preprints 2026 置信度 0.74
• Molecular characterisation of malaria and glucose-6-phosphate dehydrogenase deficiency in conflict-affected zones of central and eastern Sudan
  preprints 2026 置信度 0.74
• APOE4 Genotype is Associated with Reduced Cortical VEGFR2 ( <i>KDR</i> ) Transcript Levels Independent of Endothelial Abundance: An AMP-AD RNA-seq Pilot Study
  Background Apolipoprotein E4 ( APOE4 ) is the strongest common genetic risk factor for late-onset Alzheimer’s disease and has been implicated in cerebrovascular dysfunction. Vascular endothelial growth factor receptor 2 (VEGFR2), encoded by the gene KDR , is a…
  preprints 2026 置信度 0.74
• PlantScience.ai: An LLM-Powered Virtual Scientist for Plant Science
  The accelerating growth of plant science literature presents a major challenge for researchers seeking to extract accurate, up-to-date knowledge from an increasingly fragmented and domain-specific corpus. General-purpose large language models (LLMs), while pow…
  preprints 2025 置信度 0.74
• Autopolyploidy exacerbates dominance masking under negative frequency-dependent selection : evidence from sporophytic self-incompatibility in <i>Arabidopsis arenosa</i> and <i>A. lyrata</i>
  preprints 2025 置信度 0.74
• Studying macromolecular composition in cell-cell interfaces using 3D membrane reconstitution systems
  preprints 2025 置信度 0.74
• The CYP6P4 I236M Mutation Imposes High Fitness Costs and Increases Susceptibility to Chlorfenapyr-Based Insecticide-Treated Nets in Anopheles gambiae
  preprints 2026 置信度 0.74
• Descending neurons integrate learnt information from mushroom body with context to promote escape behaviour
  To behave adaptively in the environment and select appropriate responses to sensory stimuli, animals integrate learnt information about the valences of stimuli with contextual information. While significant progress has been made in understanding how animals l…
  preprints 2025 置信度 0.74
• PlantCV v4: Image analysis software for high-throughput plant phenotyping
  ABSTRACT PlantCV is an open-source Python project aimed at developing tools to address a range of image-based, plant phenotyping questions. PlantCV has been used for more than 10 years to automate trait collection from image data and the newest release, PlantC…
  preprints 2025 置信度 0.74
• Medulloblastoma-Associated KBTBD4 Mutations Disrupt PP2A-A Orphan Quality Control
  preprints 2026 置信度 0.74
• Testing methodological and population-specific influences on the detection of Zipf’s law of brevity in chimpanzee gestures
  preprints 2025 置信度 0.74
• The anti-neural role of BMP signaling is a side effect of its global function in dorsoventral patterning
  preprints 2025 置信度 0.74
• miR-495-3p inhibition rescues mTORC1 hyperactivation-driven autistic-like behaviors in mice
  Defective social behavior and cognitive functions are hallmarks of Autism spectrum disorders (ASD). The molecular mechanisms keeping social behavior in a physiological range are largely unknown. We recently found that conditional knockout (cKO) of tmiRNA clust…
  preprints 2026 置信度 0.74
• Spatially correlated fluctuations govern relative chromatin motion
  preprints 2026 置信度 0.74
• Reference genomes of four miniature and non-miniature cypriniform fishes inhabiting acidic peat-swamp forest blackwaters of Southeast Asia
  preprints 2026 置信度 0.74
• Hybrid Quorum Sensing and Machine Learning Systems for Precision Gene Regulation: Revolutionizing Synthetic Biology and Autonomous Therapeutic Applications
  preprints 2024 置信度 0.74
• Genome-wide discovery reveals 30 loci for choroidal thickness and uncovers potential causal links with angle-closure glaucoma
  preprints 2026 置信度 0.74
• Multimodal reference brain atlas of adult <i>Danionella cerebrum</i>
  Mechanistic accounts of brain function require a common coordinate system in which structural, molecular and functional data can be integrated and compared across individuals. The teleost genus Danionella is unique among vertebrates in retaining lifelong trans…
  preprints 2026 置信度 0.74
• Deciphering Photosynthetic Protein Networks: A Crosslinking-MS Strategy for Studying Functional Thylakoid Membranes
  preprints 2025 置信度 0.74
• Diatom ultrastructural diversity across controlled and natural environments
  preprints 2025 置信度 0.74
• Detergent-free reconstitution of transmembrane proteins in giant liposomes of complex curvature by the Synthetic Membrane Transfer
  preprints 2025 置信度 0.74
• Knowledge Mapping of Clec9a on dendritic cells: A Review and Bibliometric Study (2008–2024)
  preprints 2025 置信度 0.74
• A novel method to sort and enrich sensory neurons
  preprints 2025 置信度 0.74