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• Organizing genome engineering for the gigabase scale
  Engineering the entire genome of an organism enables large-scale changes in organization, function, and external interactions, with significant implications for industry, medicine, and the environment. Improvements to DNA synthesis and organism engineering are…
  arxiv Bryan A. Bartley, Jacob Beal, Jonathan R. Karr, Elizabeth A. Strychalski 2019-09-03T22:04:34Z 置信度 0.78 q-bio.GN
• A Misclassification Network-Based Method for Comparative Genomic Analysis
  Classifying genome sequences based on metadata has been an active area of research in comparative genomics for decades with many important applications across the life sciences. Established methods for classifying genomes can be broadly grouped into sequence a…
  arxiv Wan He, Tina Eliassi-Rad, Samuel V. Scarpino 2024-12-09T23:22:15Z 置信度 0.78 q-bio.GNcs.LG
• Spectral concepts in genome informational analysis
  The concept of k-spectrum for genomes is here investigated as a basic tool to analyze genomes. Related spectral notions based on k-mers are introduced with some related mathematical properties which are relevant for informational analysis of genomes. Procedure…
  arxiv Vincenzo Bonnici, Giuditta Franco, Vincenzo Manca 2021-06-25T10:00:55Z 置信度 0.78 cs.CEq-bio.GN
• Genome assembly in the telomere-to-telomere era
  De novo assembly is the process of reconstructing the genome sequence of an organism from sequencing reads. Genome sequences are essential to biology, and assembly has been a central problem in bioinformatics for four decades. Until recently, genomes were typi…
  arxiv Heng Li, Richard Durbin 2023-08-15T16:50:40Z 置信度 0.78 q-bio.GN
• The genomic architecture and evolutionary fates of supergenes
  Supergenes are genomic regions containing sets of tightly linked loci that control multi-trait phenotypic polymorphisms under balancing selection. Recent advances in genomics have uncovered significant variation in both the genomic architecture as well as the …
  arxiv Juanita Gutiérrez-Valencia, William Hughes, Emma L. Berdan, Tanja Slotte 2020-12-21T17:26:07Z 置信度 0.78 q-bio.PEq-bio.GN
• Addressing Ancestry Disparities in Genomic Medicine: A Geographic-aware Algorithm
  With declining sequencing costs a promising and affordable tool is emerging in cancer diagnostics: genomics. By using association studies, genomic variants that predispose patients to specific cancers can be identified, while by using tumor genomics cancer typ…
  arxiv Daniel Mas Montserrat, Arvind Kumar, Carlos Bustamante, Alexander Ioannidis 2020-04-25T04:32:16Z 置信度 0.78 q-bio.GNq-bio.PE
• Genomes: at the edge of chaos with maximum information capacity
  We propose an order index, phi, which quantifies the notion of ``life at the edge of chaos'' when applied to genome sequences. It maps genomes to a number from 0 (random and of infinite length) to 1 (fully ordered) and applies regardless of sequence length. Th…
  arxiv Sing-Guan Kong, Hong-Da Chen, Wen-Lang Fan, Jan Wigger 等 2007-08-12T07:45:19Z 置信度 0.78 q-bio.GN
• A structural model of genome-wide association studies
  A structural genetic model incorporating a modern understanding of the genome and common practice in genome-wide association studies is derived mathematically. The model shows the Haldane map distance as a direct consequence of the structure of the genome. An …
  arxiv Christopher Salahub 2022-05-20T18:14:39Z 置信度 0.78 q-bio.GNstat.AP
• Slow evolution of vertebrates with large genomes
  Darwin introduced the concept of the "living fossil" to describe species belonging to lineages that have experienced little evolutionary change, and suggested that species in more slowly evolving lineages are more prone to extinction (1). Recent studies reveal…
  arxiv Bianca Sclavi, John Herrick 2011-09-10T11:20:50Z 置信度 0.78 q-bio.GNq-bio.PE
• Beyond the exome: what's next in diagnostic testing for Mendelian conditions
  Despite advances in clinical genetic testing, including the introduction of exome sequencing (ES), more than 50% of individuals with a suspected Mendelian condition lack a precise molecular diagnosis. Clinical evaluation is increasingly undertaken by specialis…
  arxiv Monica H. Wojcik, Chloe M. Reuter, Shruti Marwaha, Medhat Mahmoud 等 2023-01-18T08:14:31Z 置信度 0.78 q-bio.GN
• Genome Sizes and the Benford Distribution
  Data on the number of Open Reading Frames (ORFs) coded by genomes from the 3 domains of Life show some notable general features including essential differences between the Prokaryotes and Eukaryotes, with the number of ORFs growing linearly with total genome s…
  arxiv James L. Friar, Terrance Goldman, Juan Pérez-Mercader 2012-05-29T22:39:47Z 置信度 0.78 q-bio.GNphysics.bio-phphysics.data-anq-bio.QM
• Comparative Assembly Hubs: Web Accessible Browsers for Comparative Genomics
  We introduce a pipeline to easily generate collections of web accessible UCSC genome browsers interrelated by an alignment. Using the alignment, all annotations and the alignment itself can be efficiently viewed with reference to any genome in the collection, …
  arxiv Ngan Nguyen, Glenn Hickey, Brian J. Raney, Joel Armstrong 等 2013-11-05T22:28:16Z 置信度 0.78 q-bio.GN
• GEMINI: integrative exploration of genetic variation and genome annotations
  Modern DNA sequencing technologies enable geneticists to rapidly identify genetic variation among many human genomes. However, isolating the minority of variants underlying disease remains an important, yet formidable challenge for medical genetics. We have de…
  arxiv Uma Paila, Brad Chapman, Rory Kirchner, Aaron Quinlan 2013-04-17T15:31:05Z 置信度 0.78 q-bio.GN
• Synteny in Bacterial Genomes: Inference, Organization and Evolution
  Genes are not located randomly along genomes. Synteny, the conservation of their relative positions in genomes of different species, reflects fundamental constraints on natural evolution. We present approaches to infer pairs of co-localized genes from multiple…
  arxiv Ivan Junier, Olivier Rivoire 2013-07-16T14:41:59Z 置信度 0.78 q-bio.GN
• Weighted genomic distance can hardly impose a bound on the proportion of transpositions
  Genomic distance between two genomes, i.e., the smallest number of genome rearrangements required to transform one genome into the other, is often used as a measure of evolutionary closeness of the genomes in comparative genomics studies. However, in models th…
  arxiv Shuai Jiang, Max A. Alekseyev 2010-12-11T02:26:27Z 置信度 0.78 q-bio.GNcs.DMq-bio.PE
• Pathogen Genomics
  This chapter evaluates pathogen genomics. As scientists developed sequencing tools at the end of the 1970s, virus genomes were the first to be tackled, because of their small size. Viruses, and then bacteria, formed the test bed for developments that went on t…
  crossref Lia Chappell, Sarah J Lindsay, Phil Jones, Julian Parkhill 等 2023-09-15T10:32:53Z 置信度 0.70
• Corrigendum to “Symbiont genomics, our new tangled bank” [Genomics 95 (2010) 129–137]
  crossref M. Medina, J.L. Sachs 2010-08-20T06:41:00Z 置信度 0.70
• 1. What is genomics?
  The term ‘genome’ is used to refer to the sum total of DNA inside the single or multiple cells that make up an organism. Complex organisms often have more than one genome. ‘What is genomics?’ looks at the biology of the two main types of cells—prokaryotes and …
  crossref John Archibald 2018-03-22T11:02:07Z 置信度 0.70
• Parasite Genomics
  This chapter focuses on parasite genomics. Parasitic infections may have beneficial effects on our immune systems, and the possibility that parasites have the potential to deliver previously unrecognized benefits as well as causing devastating harm makes it ev…
  crossref Lia Chappell, Sarah J Lindsay, Phil Jones, Julian Parkhill 等 2023-09-15T07:40:11Z 置信度 0.70
• BMC Genomics reviewer acknowledgement 2015
  crossref Derek Anane 2016-03-02T09:22:20Z 置信度 0.70
• Exploring evolutionary adaptations through Phoxinus phoxinus genomics
  crossref Jitendra Narayan 2024-09-03T18:29:28Z 置信度 0.70
• Cancer Genomics
  This chapter discusses cancer genomics, which is one of the fastest-moving areas of medical research and is having a direct impact on people's lives. Cancer is a disease in which cells divide in excess, generating a lump, known as the primary tumour. A key fea…
  crossref Lia Chappell, Sarah J Lindsay, Phil Jones, Julian Parkhill 等 2023-09-15T13:33:22Z 置信度 0.70
• The Genetics and Genomics of Cancer
  This chapter examines the role of genetics and genomics in cancer development, focusing on how hereditary, environmental, and random factors contribute to oncogenesis. It explains how genetic mutations provide abnormal cells with a growth advantage, allowing t…
  crossref Heather Williams, Zoe Hatt 2025-12-10T16:32:03Z 置信度 0.70
• Genomics: Structural and Functional Studies of Genomes
  crossref 2002-09-17T18:31:03Z 置信度 0.70
• Technology development driving genomics and life sciences
  crossref 2021-10-13T22:20:25Z 置信度 0.70
• 7. The future of genomics
  ‘The future of genomics’ explores some of the ways in which genome science will continue to expand the frontiers of human knowledge, as well as change our world and the way we interact with it. Important ethical, legal, and social issues have already been rais…
  crossref John Archibald 2018-03-22T11:03:18Z 置信度 0.70
• Web-based resources for comparative genomics
  crossref Xun Gu, Zhixi Su 2012-07-21T07:01:31Z 置信度 0.70
• Reflecting the bright future of genomics
  crossref 2002-09-17T18:31:03Z 置信度 0.70
• Survival analysis tools in genomics research
  crossref Xintong Chen, Xiaochen Sun, Yujin Hoshida 2014-11-24T20:02:16Z 置信度 0.70
• Peer Community in Genomics
  crossref 2020-09-24T03:11:10Z 置信度 0.70
• CoGemiR: A comparative genomics microRNA database
  crossref Vincenza Maselli, Diego Di Bernardo, Sandro Banfi 2008-10-14T14:14:45Z 置信度 0.70
• Gene Therapy Tools for Functional Genomics
  crossref Fintan R. Steele 2002-10-06T18:49:14Z 置信度 0.70
• The genomics of gene expression
  crossref John A. Stamatoyannopoulos 2004-07-08T03:50:17Z 置信度 0.70
• Three‐dimensional genomics (3D genomics)
  crossref 2015-12-18T08:43:31Z 置信度 0.70
• 6. Genomics and the microbial world
  Together, molecular biology and genomics have made it possible to explore the diversity and ecology of the 99 per cent of microbes that cannot be cultured in laboratories. ‘Genomics and the microbial world’ considers environmental gene sequencing; metagenomics…
  crossref John Archibald 2018-03-22T11:03:17Z 置信度 0.70
• Genomics Special Issue on 5-hydroxymethylation
  crossref Guoliang Xu, Colum Walsh 2014-10-22T18:28:59Z 置信度 0.70
• Biomedical Genetics and Genomics
  crossref 2016-08-16T09:19:20Z 置信度 0.70
• Book Reviews
  crossref 2012-07-30T09:42:30Z 置信度 0.70
• Improving the specificity of exon prediction using comparative genomics
  crossref Jing Wu 2008-09-16T19:57:17Z 置信度 0.70
• Pharmacogenetics and Genomics, 2005
  crossref &NA; 2008-05-04T10:12:39Z 置信度 0.70
• Genomics Research: World Survey of Public Funding
  crossref Jennifer Pohlhaus, Robert M Cook-Deegan 2008-10-10T14:13:46Z 置信度 0.70
• Genomics software: The view from 10,000 feet
  crossref Michael E Weale 2019-12-11T02:56:52Z 置信度 0.70
• JSM Genetics & Genomics
  crossref 2024-05-04T04:12:52Z 置信度 0.70
• Metagenomics (environmental genomics, ecogenomics, community genomics)
  crossref 2015-12-15T22:18:54Z 置信度 0.70
• Editorial
  crossref Vasilis Vasiliou 2012-07-16T12:15:28Z 置信度 0.70
• Human Genomics and Proteomics
  crossref 2009-08-09T13:34:20Z 置信度 0.70
• Population Genomics of Bacteriophages
  crossref Harald Brüssow 2018-03-14T10:03:09Z 置信度 0.70
• The Impact of Genomics on Human Health and Disease
  This chapter examines how genomics advances the understanding and treatment of human diseases by identifying genetic mutations, mapping disease-associated genes, and applying genome-wide association studies (GWAS). Mutations in specific genes cause inherited d…
  crossref Arthur M. Lesk 2025-10-10T07:06:05Z 置信度 0.70
• Genomics for all: Open, collaborative, pioneering
  crossref Orli G. Bahcall 2021-10-13T22:20:19Z 置信度 0.70
• Pseudomonas syringae Genomics: From Comparative Genomics of Individual Crop Pathogen Strains Toward Population Genomics
  crossref Boris A. Vinatzer, Caroline L. Monteil 2014-06-19T11:14:56Z 置信度 0.70
• Stemming the Tide of Genomics: Computational Genomics III
  crossref Christine L. Carter, Anthony R. Kerlavage 2002-07-26T18:06:55Z 置信度 0.70
• Editorial
  crossref Li Jin 2012-07-28T00:42:43Z 置信度 0.70
• A new Editorial Team and Scope for Marine Genomics
  crossref 2012-02-10T14:32:52Z 置信度 0.70
• Legume Comparative Genomics
  crossref Steven Cannon 2008-05-06T17:03:25Z 置信度 0.70
• Comparative genomics reveals evidence of marine adaptation in Salinispora species
  crossref Kevin Penn, Paul R Jensen 2012-03-08T08:14:15Z 置信度 0.70
• Physiological genomics special issue on animal functional genomics
  crossref Jeanne L. Burton, Guilherme J. M. Rosa 2006-12-13T15:03:17Z 置信度 0.70
• Public Health Genomics
  crossref 2015-03-24T07:21:22Z 置信度 0.70
• USDA animal genomics program: the view from the chicken coop
  crossref Janet E Fulton 2009-07-14T18:16:03Z 置信度 0.70
• GIA 2013: Genomics in Aquaculture 2013 symposium
  crossref Zhanjiang Liu 2014-10-24T09:18:21Z 置信度 0.70
• Genomics in the German Democratic Republic
  crossref Ch. Coutelle, A. Speer 2004-12-06T21:20:49Z 置信度 0.70
• Fungal genomics
  crossref A. Tsang 2014-11-19T05:44:56Z 置信度 0.70
• 16th Carbonyl Metabolism Meeting: from enzymology to genomics
  crossref Edmund Maser 2012-12-01T17:14:22Z 置信度 0.70
• Genomics made easier: An introductory tutorial to genome datamining
  crossref Peter Schattner 2008-12-06T10:25:30Z 置信度 0.70
• Microbial comparative pan-genomics using binomial mixture models
  crossref Lars Snipen, Trygve Almøy, David W Ussery 2009-08-19T14:14:15Z 置信度 0.70
• Retraction
  crossref 2002-10-06T20:18:03Z 置信度 0.70
• Rare Diseases: A Genomics Perspective
  This chapter provides an overview of genomics, which is the study of the structure and function of genomes. A genome is the complete set of genetic instructions for an organism. Genomics is a huge area of study that encompasses many different (and sometimes co…
  crossref Lia Chappell, Sarah J Lindsay, Phil Jones, Julian Parkhill 等 2023-09-15T07:24:37Z 置信度 0.70
• Functional genomics (III): Submitting your data and functional genomics databases
  crossref 2016-06-29T10:31:41Z 置信度 0.70
• Editorial
  crossref PY Kwok 2012-07-21T07:02:51Z 置信度 0.70
• Genomics informatics - Clinical genomics data sharing specification for next-generation sequencing
  crossref 2023-07-12T20:30:30Z 置信度 0.70
• Announcement
  crossref 2004-12-07T13:55:14Z 置信度 0.70
• Editorial
  crossref David D Pollock 2012-07-28T06:34:31Z 置信度 0.70
• Nutritional genomics
  The integration of genomics into nutritional sciences has illuminated the complexity of genome responses to nutritional exposures while offering opportunities to increase the effectiveness of nutritional interventions, both clinical and population based. Nutri…
  crossref Patrick J. Stover 2004-01-30T20:05:02Z 置信度 0.70
• A new home for Human Genomics
  crossref Vasilis Vasiliou, Daniel W Nebert 2012-07-05T16:30:47Z 置信度 0.70
• Visionary genomics
  crossref J. Mark Petrash, Philip A. Ruzycki, Gregory J. Zablocki 2019-12-10T21:30:22Z 置信度 0.70
• Argentina: Public Health Genomics
  Argentina’s population numbers about 40 million, with main genetic contributions from Europeans, Amerindians and, to a much lower extent, West Africans. There is a traditional health care system publicly funded coexisting with a social security system and a fo…
  crossref V.B. Penchaszadeh 2008-09-11T10:20:01Z 置信度 0.70
• An Ac/Ds-mediated gene trap system for functional genomics in barley
  crossref Katina Lazarow, Stephanie Lütticke 2009-01-29T19:18:09Z 置信度 0.70
• Genomics: Reading and Writing Genomes
  This chapter explores the incredible advances which have taken place—and are still taking place—in the technologies involved in DNA sequencing and in DNA manipulation. The invention of DNA sequencing technology enabled DNA to be read for the first time in the …
  crossref Lia Chappell, Sarah J Lindsay, Phil Jones, Julian Parkhill 等 2023-09-15T08:21:46Z 置信度 0.70
• Current Trends in Fungal Genomics and Biology
  crossref Clint Magill 2012-10-23T08:59:24Z 置信度 0.70
• Celebrating 20 years of human genomics: a journey of discovery
  crossref Vasilis Vasiliou 2024-01-02T05:42:40Z 置信度 0.70
• NCBI GEO: archive for functional genomics data sets—update
  The Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) is an international public repository for high-throughput microarray and next-generation sequence functional genomic data sets submitted by the research community. The resource supports archiv…
  openalex Tanya Barrett, Stephen E. Wilhite, Pierre Ledoux, Carlos Evangelista 等 2012-11-26 置信度 0.72 MetadataDownloadBiologyRaw dataGenomics
• Accounting for multiple imputation-induced variability for differential analysis in mass spectrometry-based label-free quantitative proteomics
  Imputing missing values is common practice in label-free quantitative proteomics. Imputation aims at replacing a missing value with a user-defined one. However, the imputation itself may not be optimally considered downstream of the imputation process, as impu…
  arxiv Marie Chion, Christine Carapito, Frédéric Bertrand 2021-08-16T13:40:35Z 置信度 0.78 stat.MEq-bio.QMstat.AP
• Using R and Bioconductor for proteomics data analysis
  This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features that make R and its add-on package…
  arxiv Laurent Gatto, Andy Christoforou 2013-05-28T17:10:30Z 置信度 0.78 q-bio.GN
• Automating Exploratory Proteomics Research via Language Models
  With the development of artificial intelligence, its contribution to science is evolving from simulating a complex problem to automating entire research processes and producing novel discoveries. Achieving this advancement requires both specialized general mod…
  arxiv Ning Ding, Shang Qu, Linhai Xie, Yifei Li 等 2024-11-06T08:16:56Z 置信度 0.78 cs.AIq-bio.QM
• Revisiting the thorny issue of missing values in single-cell proteomics
  Missing values are a notable challenge when analysing mass spectrometry-based proteomics data. While the field is still actively debating on the best practices, the challenge increased with the emergence of mass spectrometry-based single-cell proteomics and th…
  arxiv Christophe Vanderaa, Laurent Gatto 2023-04-13T16:34:26Z 置信度 0.78 q-bio.QMq-bio.GN
• Sampling the proteome by emerging single-molecule and mass-spectrometry methods
  Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine these implications for …
  arxiv Michael J. MacCoss, Javier Alfaro, Meni Wanunu, Danielle A. Faivre 等 2022-07-31T21:59:40Z 置信度 0.78 q-bio.QM
• Toward a better analysis of secreted proteins: the example of the myeloid cells secretome
  The analysis of secreted proteins represents a challenge for current proteomics techniques. Proteins are usually secreted at low concentrations in the culture media, which makes their recovery difficult. In addition, culture media are rich in salts and other c…
  arxiv Mireille Chevallet, Hélène Diemer, Alain van Dorsselaer, Christian Villiers 等 2007-03-02T10:35:11Z 置信度 0.78 q-bio.GN
• The current state of single-cell proteomics data analysis
  Sound data analysis is essential to retrieve meaningful biological information from single-cell proteomics experiments. This analysis is carried out by computational methods that are assembled into workflows, and their implementations influence the conclusions…
  arxiv Christophe Vanderaa, Laurent Gatto 2022-10-03T15:33:45Z 置信度 0.78 q-bio.QM
• In silico Proteome Cleavage Reveals Iterative Digestion Strategy for High Sequence Coverage
  In the post-genome era, biologists have sought to measure the complete complement of proteins, termed proteomics. Currently, the most effective method to measure the proteome is with shotgun, or bottom-up, proteomics, in which the proteome is digested into pep…
  arxiv Jesse G. Meyer 2014-02-07T23:13:48Z 置信度 0.78 q-bio.GNcs.CE
• Deep Learning in Proteomics Informatics: Applications, Challenges, and Future Directions
  Deep learning is an advanced technology that relies on large-scale data and complex models for feature extraction and pattern recognition. It has been widely applied across various fields, including computer vision, natural language processing, and speech reco…
  arxiv Yindan Luo, Jiaxin Cai 2024-12-23T07:21:27Z 置信度 0.78 q-bio.GN
• Single-Cell Proteomics Using Mass Spectrometry
  Single-cell proteomics (SCP) is transforming our understanding of biological complexity by shifting from bulk proteomics, where signals are averaged over thousands of cells, to the proteome analysis of individual cells. This granular perspective reveals distin…
  arxiv Amanda Momenzadeh, Jesse G. Meyer 2025-02-17T16:22:55Z 置信度 0.78 q-bio.QMq-bio.GN
• Liquid chromatography mass spectrometry-based proteomics: Biological and technological aspects
  Mass spectrometry-based proteomics has become the tool of choice for identifying and quantifying the proteome of an organism. Though recent years have seen a tremendous improvement in instrument performance and the computational tools used, significant challen…
  arxiv Yuliya V. Karpievitch, Ashoka D. Polpitiya, Gordon A. Anderson, Richard D. Smith 等 2011-01-06T07:40:25Z 置信度 0.78 stat.APq-bio.BMq-bio.QM
• A Foundation Model for Spatial Proteomics
  Foundation models have begun to transform image analysis by acting as pretrained generalist backbones that can be adapted to many tasks even when post-training data are limited, yet their impact on spatial proteomics, imaging that maps proteins at single-cell …
  arxiv Muhammad Shaban, Yuzhou Chang, Huaying Qiu, Yao Yu Yeo 等 2025-06-03T20:30:25Z 置信度 0.78 cs.CVcs.AI
• A model of large-scale proteome evolution
  The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have shown that its topol…
  arxiv Ricard V. Sole, Romualdo Pastor-Satorras, Eric Smith, Thomas B. Kepler 2002-07-12T08:37:01Z 置信度 0.78 cond-mat.stat-mechq-bio
• Cell wall proteins: a new insight through proteomics
  Cell wall proteins are essential constituents of plant cell walls; they are involved in modifications of cell wall components, wall structure, signaling and interactions with plasma membrane proteins at the cell surface. The application of proteomic approaches…
  arxiv Elisabeth Jamet, Hervé Canut, Georges Boudart, Rafael F Pont-Lezica 2006-10-12T13:26:03Z 置信度 0.78 q-bio.GN
• Subcellular proteome niche discovery using semi-supervised functional clustering
  Intracellular compartmentalization of proteins underpins their function and the metabolic processes they sustain. Various mass spectrometry-based proteomics methods (subcellular spatial proteomics) now allow high throughput subcellular protein localization. Ye…
  arxiv Ziyue Zheng, Loay J. Jabre, Matthew McIlvin, Mak A. Saito 等 2025-12-08T22:42:16Z 置信度 0.78 q-bio.QMq-bio.SCstat.AP
• HEIST: A Graph Foundation Model for Spatial Transcriptomics and Proteomics Data
  Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell level. With the advent o…
  arxiv Hiren Madhu, João Felipe Rocha, Tinglin Huang, Siddharth Viswanath 等 2025-06-11T12:29:01Z 置信度 0.78 q-bio.GNcs.LGq-bio.CB
• Towards Scalable Proteomics: Opportunistic SMC Samplers on HTCondor
  Quantitative proteomics plays a central role in uncovering regulatory mechanisms, identifying disease biomarkers, and guiding the development of precision therapies. These insights are often obtained through complex Bayesian models, whose inference procedures …
  arxiv Matthew Carter, Lee Devlin, Alexander Philips, Edward Pyzer-Knapp 等 2025-09-09T08:54:13Z 置信度 0.78 q-bio.QMcs.DCstat.CO
• Refining Platelet Purification Methods: Enhancing Proteomics for Clinical Applications
  Background: Platelet proteomics offers valuable insights for clinical research, yet isolating high-purity platelets remains a challenge. Current methods often lead to contamination or platelet loss, compromising data quality and reproducibility. Objectives: Th…
  arxiv Vibecke Markhus, Katarina Fritz-Wallace, Olav Mjaavatten, Einar K. Kristoffersen 等 2025-05-30T09:24:18Z 置信度 0.78 q-bio.BMq-bio.GN
• Sparse Proteomics Analysis - A compressed sensing-based approach for feature selection and classification of high-dimensional proteomics mass spectrometry data
  Background: High-throughput proteomics techniques, such as mass spectrometry (MS)-based approaches, produce very high-dimensional data-sets. In a clinical setting one is often interested in how mass spectra differ between patients of different classes, for exa…
  arxiv Tim Conrad, Martin Genzel, Nada Cvetkovic, Niklas Wulkow 等 2015-06-11T10:55:49Z 置信度 0.78 math.STstat.ML
• Foundation model for mass spectrometry proteomics
  Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated computational method…
  arxiv Justin Sanders, Melih Yilmaz, Jacob H. Russell, Wout Bittremieux 等 2025-05-16T04:40:07Z 置信度 0.78 cs.LG