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• A novel framework for integrating post-mortem images with 3D body models for automatic injury medical documentation.
  Forensic medicine is critical in criminal investigations, providing essential insights into the nature and mechanisms of injuries. Traditional post-mortem examination remains mostly manual, which introduces risks of error and inefficiency, particularly in inju…
  pubmed Kalinowska KB, Wilkowski A, Markiewicz J, Zawieska D 等 2026 Aug 置信度 0.82
• Head-to-head comparison of [(18)F]-mFBG versus [(123)I]-MIBG in neuroblastoma: a systematic review and meta-analysis.
  Hybrid imaging is fundamental in the staging and response assessment of patients affected by neuroblastoma (NB). [ 123 I]-metaiodobenzylguanidine (MIBG) scintigraphy±single-photon emission computed tomography/computed tomography (SPECT/CT) is considered t…
  pubmed Albano D, Bertagna F, Piccardo A, Fiz F 等 2026 Jul 8 置信度 0.82
• Hydrogel degradation products as immunomodulatory cues in neural injury: mechanisms and implications for neural repair.
  Neural tissue engineering often uses hydrogels due to their tunable biophysical properties and biocompatibility. While much attention has been devoted to hydrogel mechanics and degradation kinetics, the role of hydrogel degradation byproducts in neural immune …
  pubmed Kishore J, Owen La Boucan FS, Abazari MF, Baldo KA 等 2026 Jul 29 置信度 0.82
• CODAvision: best practices and a user-friendly interface for rapid, customizable segmentation of medical images.
  Image-based machine learning tools are powerful resources for analyzing medical images, with deep learning-based semantic segmentation commonly utilized to enable the spatial quantification of structures visible in images. However, dataset generation and train…
  pubmed Matos-Romero V, Gómez-Becerril J, Forjaz A, Dequiedt L 等 2026 Jul 7 置信度 0.82
• Molecular crowding and amyloidogenic self-assembly: Emergent perspectives from modern computations.
  Macromolecular crowding defines the cellular interior, where high biomolecule concentrations reshape protein folding landscapes and intermolecular interactions. Excluded-volume effects, quinary interactions, and spatial confinement collectively modulate amyloi…
  pubmed Pandey S, Sengupta N 2026 Aug 置信度 0.82
• Image Restoration via Multi-domain Learning.
  Due to adverse atmospheric and imaging conditions, natural images suffer from various degradation phenomena. Consequently, image restoration has emerged as a key solution and garnered substantial attention. Although recent Transformer architectures have demons…
  pubmed Jiang X, Gao N, Zhang X, Dou H 等 2026 Jul 7 置信度 0.82
• An integrated toolkit for structure generation, optimization, and evaluation in spatially fractionated radiation therapy.
  Spatially fractionated radiation therapy (SFRT) planning requires three coordinated tasks: generation of high-dose sphere structures, position-aware optimization, and peak-valley dose ratio evaluation. In practice, clinicians and researchers address these task…
  pubmed Patel JK, Magliari A, Gill G, Wareing TA 等 2026 Jul 置信度 0.82
• Multiscale systems modelling of communication networks in brain metastasis.
  Brain metastasis remains a major clinical challenge because intracranial progression and therapeutic resistance arise not only from tumour-intrinsic programmes but also from coordinated communication across molecular, cellular, spatial and systemic scales. In …
  pubmed Ahn JY, Dong W, Wong ST, Zhao H 2026 Jul 置信度 0.82
• Photon-counting detector computed tomography for temporal bone: does higher resolution matter?
  Photon-counting detector computed tomography (PCD-CT) represents a major technological advancement in computed tomography, offering improved spatial resolution, reduced image noise, and increased dose efficiency compared with conventional energy-integrating de…
  pubmed Epperson MV, Leng S, Lane JI, Carlson ML 2026 Jul 7 置信度 0.82
• A Critical Review of PET/CT Assessment After CAR-T Cell Therapy in Large B-Cell Lymphoma, Limitations of Current Criteria, Emerging Biomarkers, and a Framework for Standardised Evaluation.
  Chimeric antigen receptor (CAR) T-cell therapy has fundamentally altered the management of relapsed or refractory Large B-Cell Lymphoma (LBCL). Despite remarkable clinical efficacy, the radiologic evaluation of therapeutic response remains highly problematic. …
  pubmed Jambi LK, Kabrah SM 2026 置信度 0.82
• Research opportunities to advance cardiovascular health through a planetary health lens.
  Cardiovascular health (CVH) across the life course requires stable, nurturing environments and a healthy planet. Increasing human demands on the earth's resources destabilize our world's ecosystems, compromising CVH. Unique research opportunities for cardiovas…
  pubmed Angell SY, Al-Kindi S, Daher B, Magid HSA 等 2026 Oct 置信度 0.82
• Epigenetic regulation of vertebrate limb development: from field specification to tissue morphogenesis.
  Vertebrate limb development provides an excellent model for understanding how epigenetic mechanisms coordinate the integration of positional information and temporal signals to generate complex three-dimensional structures. An increasing body of evidence shows…
  pubmed Vallejo-De Lira CM, Galván-Hernández CI, Chimal-Monroy J, Marin-Llera JC 2026 Dec 置信度 0.82
• Intraoperative technological advances and new frontiers in precision glioma surgery.
  Diffuse gliomas remain among the most surgically challenging tumors, characterized by their infiltrative nature, proximity to eloquent brain structures, and the formidable barrier posed by the BBB to systemic therapeutic delivery. Maximizing extent of resectio…
  pubmed Faraj CA, Young CC, Beckham TH, Weinberg JS 2026 Jul 4 置信度 0.82
• Active devices and systems for closed-loop neuromodulation.
  Neuromodulation has become a central topic in neuroscience and biomedical engineering, as it provides powerful means to interrogate and regulate neural activity and offers promising therapeutic strategies for a wide range of neurological disorders. Conventiona…
  pubmed Wang J, Xue H, Li J, Li Y 等 2026 Jul 3 置信度 0.82
• Advances in intraoperative margin assessment for solid tumors: Toward a new era of personalized precision surgery.
  The accurate determination of surgical margin status remains a core challenge in the curative surgery of solid tumors. Conventional methods relying on intraoperative frozen sections and empirical surgeon judgment often fall short due to insufficient spatial re…
  pubmed Gao Z, Zhao L, Li Z, Wang R 等 2026 Sep 置信度 0.82
• From candidate genes to omics: Unbiased approaches reshaping arthropod Evo-Devo.
  Drosophila melanogaster established the candidate-gene paradigm that shaped arthropod evolutionary developmental biology (Evo-Devo) for decades. Genome-wide methods-bulk RNA-seq, single-cell/single-nucleus transcriptomics, chromatin profiling (ATAC-seq, CUT&am…
  pubmed Vieira J, Nunes-da-Fonseca R 2026 置信度 0.82
• Snapshot 3D at the speed frontier: redefining light-field microscopy for neuroimaging.
  Neural activity unfolds across three-dimensional circuits on millisecond-to-microsecond timescales, yet most optical microscopes still acquire volumes sequentially, limiting their ability to capture fast, distributed dynamics. Light-field microscopy (LFM) addr…
  pubmed Zhao R, Park J, Gao L 2026 置信度 0.82
• Methodological Design for Three-Dimensional Assessment of Maxillary and Mandibular Impacted Canines by Cone-Beam Computed Tomography: A Scoping Review.
  To map and critically synthesize the methodological approaches used for the CBCT-based evaluation of maxillary and mandibular impacted canines (ICs), with emphasis on imaging protocols, anatomical variables, and diagnostic frameworks. This scoping review follo…
  pubmed Gurgel M, Saraiva AC, Pereira AB, Carvalho FSR 等 2026 Jul 2 置信度 0.82
• Critical assessment of synthetic microbial community strategies in vinegar brewing: from design paradigms to industrialization bottlenecks.
  Vinegar brewing traditionally relies on complex, spontaneously assembled microbiota, which often results in batch-to-batch inconsistency and uncontrollable flavor profiles due to environmental fluctuations. Synthetic microbial communities (SynComs) represent a…
  pubmed Lin S, Yu Y, Zhu Y, Wang K 等 2026 Jul 2 置信度 0.82
• 3D-Printing in Neurosurgical Training: Hands-On Practice, Patient-Specific Planning and Simulation.
  Training in neurosurgery is increasingly challenged by the complexity of cranial anatomy, the rarity of certain pathologies, ethical constraints on cadaveric dissection, and limited operative exposure. Advances in three-dimensional (3D) printing have enabled t…
  pubmed Coelho G, Freeman WD 2026 置信度 0.82
• Spatial transcriptomics in ovarian biology technologies: computational challenges, and biological insights.
  In brief: This review synthesizes the technical landscape of current spatial transcriptomic platforms, addresses computational challenges unique to ovarian tissue, and surveys biological discoveries across ovarian development, aging, follicle dynamics, and can…
  pubmed Huang R, Goods BA 2026 Jul 3 置信度 0.82
• Seeing the invisible: practical strategies to maximize the clinical impact of photon-counting CT in abdominal imaging.
  Photon-counting detector computed tomography (PCD-CT) represents a major technological advance, transforming abdominal imaging from morphology-based assessment to a platform that integrates spectral and quantitative information. Unlike conventional energy-inte…
  pubmed Yokoyama K, Kawasaki Y, Fujii M, Yamada H 等 2026 Jul 2 置信度 0.82
• Spatial metabolomics in medicinal plant research: current advances, technical challenges, and future perspectives.
  Secondary metabolites derived from medicinal plants represent a critical resource for drug discovery and play an indispensable role in the prevention and treatment of major human diseases. Spatial metabolomics has emerged as a transformative approach that over…
  pubmed Gong Y, Yang D, Hou Z 2026 Jul 16 置信度 0.82
• Deep learning-assisted structural color inverse design: a perspective.
  Structural color, a special color generated by the interaction of visible light with nanostructures, has attracted significant research interest and industrial attention due to its promising advantages of long-term stability, spatial resolution, sustainability…
  pubmed Ma T, Guo LJ 2026 Aug 19 置信度 0.82
• Test-retest reliability of spatiotemporal, kinematic, and kinetic measures in marker-based 3D gait analysis: A systematic review.
  Marker-based 3D gait analysis (3DGA) is widely used to quantify impairments and evaluate treatment effects. For longitudinal clinical interpretation, clinicians and researchers need reference values for inter-session measurement error. For this purpose, this s…
  pubmed Horsak B, Kranzl A, Slijepcevic D, Svehlik M 等 2026 Oct 置信度 0.82
• Connecting the dots in plant metabolism: Isotopic labeling and metabolic flux analysis.
  Sustainable agriculture and bio-based production require a quantitative understanding of how living systems allocate carbon, energy, and nutrients. Metabolic Flux Analysis (MFA) addresses this need by combining stable isotope tracing with computational modelin…
  pubmed Kambhampati S, Combs-Giroir R, Demiwal P, Koley S 等 2026 Aug 置信度 0.82
• Tomogram exploration through template matching and deep learning.
  Template matching (TM) is a long-standing tool in cryo-electron tomography (cryo-ET), where it has been applied to localize macromolecular complexes across a wide range of sample types. Recent algorithmic and computational advances have substantially increased…
  pubmed Coray R, Molina-Ribagorda A, Castaño-Díez D 2026 Jul 1 置信度 0.82
• Immune-tumor cell ligand-receptor axes driving metabolic reprogramming and therapeutic resistance in cancer.
  Therapeutic resistance remains a major barrier to durable cancer control and cannot be fully explained by tumor-intrinsic genetic and epigenetic alterations alone. Increasing evidence indicates that resistance emerges within a dynamic tumor microenvironment in…
  pubmed Zhu H, Yi W, Wu Y, Li R 等 2026 置信度 0.82
• OpenIMC: an open-source platform for analyzing single-cell and spatial proteomics by imaging mass cytometry.
  Imaging Mass Cytometry (IMC) enables highly multiplexed, spatially resolved single-cell proteomics, providing simultaneous measurement of dozens of protein markers while preserving tissue architecture. Despite its analytical power, IMC data analysis remains fr…
  pubmed Tessone D, Kamal M, Hennes V, Saadawy AH 等 2026 Jun 30 置信度 0.82
• Spatial remodeling of bone marrow architecture defines tissue-state signatures of disease activity and therapeutic response in myelodysplastic neoplasms.
  Myelodysplastic neoplasms (MDS) disrupt bone marrow hematopoiesis, yet clinical assessment relies largely on blast enumeration and qualitative morphology, which incompletely capture marrow architecture and disease state. We applied whole-slide multiplex immuno…
  pubmed Nachman R, Kopacz A, Unkenholz C, Chai J 等 2026 Aug 置信度 0.82
• Spatial transcriptomics in cancer research: insights into tumorigenesis, diagnosis and therapeutics.
  Spatial transcriptomics is an innovative technology that enables high-throughput, genome-wide analysis of transcript expression and spatial localization within tissues. By preserving structural organization, it provides critical insights into tumor sub-regions…
  pubmed Wen Q, Lan Q, Yin J, Guo F 等 2026 Jun 30 置信度 0.82
• Geographical psychology: Spatial variation in psychological phenomena and their consequences.
  Psychological traits are not uniformly distributed across space; they are geographically clustered. The emerging interdisciplinary field of geographical psychology integrates insights from psychology and the social sciences to understand the causes and consequ…
  pubmed Rentfrow PJ, Ebert T, Götz FM 2026 Jun 30 置信度 0.82
• Cross-scale bioanalytical integration for decoding tumour regulatory plasticity in oncology.
  Cancer is characterized by extensive genetic variability, continuous evolutionary change, and intricate interactions with its surrounding microenvironment and causing substantial challenges for precise diagnosis, prognostic evaluation and therapeutic selection…
  pubmed Kumar S, Mondal A, Dubey VK 2026 Sep 置信度 0.82
• Self-supervised isotropic reconstruction for abnormality detection in anisotropic MRI.
  Accelerating musculoskeletal magnetic resonance imaging (MRI) while preserving diagnostic detail remains challenging because acquiring fully‑isotropic ground‑truth volumes is clinically costly. In routine practice, anisotropic scans with reduced …
  pubmed Hsu JY, Lian PH, Chuang TY, Chen YH 等 2026 Jul 置信度 0.82
• Integrating single-cell RNA sequencing with multi-omics to decode disease microenvironments.
  Cellular heterogeneity underpins the complexity of human development and disease, as cells with the same genome exhibit distinct transcriptomic profiles that define their identity, state, and function. Traditional bulk RNA sequencing obscures this heterogeneit…
  pubmed Devi A, Pathak V, Dwibedi V, Singh J 等 2026 Jun 30 置信度 0.82
• MPM-based simulation and bounded-error compression of material points for magnetic tactile sensors.
  Tactile sensing provides critical contact feedback for precision robotic micro-assembly, particularly in visually occluded environments common in 3C (Computer, Communication, and Consumer Electronics) manufacturing. Magnetic tactile sensors are especially prom…
  pubmed Lin X, Lin G, Liu R, Wang A 等 2026 置信度 0.82
• Failure modes and effects analysis of LINAC-based stereotactic arrhythmia radioablation categorized by segmental targets.
  Stereotactic arrhythmia radioablation (STAR) is an emerging treatment for refractory or recurrent arrhythmias. Compared with conventional stereotactic body radiotherapy (SBRT), STAR involves greater complexity in target delineation, motion management, and orga…
  pubmed Li J, Wu Y, Chen Q, Guo H 等 2026 Jun 29 置信度 0.82
• Decoding glioblastoma evolution and heterogeneity through mechanistic modeling: implications for clinical translation.
  Glioblastoma (GBM) is one of the most aggressive and lethal primary brain tumors in adults, characterized by dynamic clonal evolution and extensive genomic, cellular, spatial, and microenvironmental heterogeneity. Multi-omics studies have revealed that GBM fol…
  pubmed Jiang H, Zhao W, Zhou H, Sun R 2026 Jun 29 置信度 0.82
• Cognitive and personality trait prediction using activation maps and temporal dynamics derived from resting-state fMRI.
  Predicting behavioral and personality traits from neuroimaging data requires effective modeling of complex and high-dimensional brain dynamics. Although recent advances in neurocomputations have paved the way for trait prediction models, the attempts remain at…
  pubmed Pasumarthi S, Jangam H, Tiwari N, Padole H 2026 Jun 29 置信度 0.82
• Improving the reproducibility of mixing-time experiments in stirred single-use bioreactors.
  Mixing time is a key metric for characterizing bioreactors, as it governs bulk homogenization and correlates with the underlying flow field and shear exposure. Having knowledge of turbulent flow regimes is particularly important for shear-sensitive (mammalian)…
  pubmed Barth I, Holbeck C, Capitain C, Schirmeister T 等 2026 Jun 29 置信度 0.82
• Chronic pain and stress: Transdiagnostic meta-analytic evidence of convergent network signature with PTSD.
  Chronic pain is increasingly conceptualized within a stress-related framework. However, it remains unclear whether chronic pain and prototypical stress-related conditions-such as post-traumatic stress disorder (PTSD)-show convergence in their morphometric alte…
  pubmed Li M, Hou Y, Liu D, Zhou Y 等 2026 Jul 13 置信度 0.82
• A blind spot of human T cell immunology: epitope specificity in secondary lymphoid organs.
  The fate of T cells is determined through the expression of a unique T cell receptor (TCR). TCR epitope specificity drives spatial localization, phenotypic and metabolic plasticity, effector function, as well as the evolution of complex repertoires of T cell c…
  pubmed Hiltensperger M, Schober K 2026 Aug 置信度 0.82
• Ruptured cerebral arteriovenous malformation associated with enlarged parietal foramina: a rare surgical case with pathogenetic implications.
  Enlarged parietal foramina (EPF) are rare, bilateral, symmetric calvarial defects, most commonly inherited in an autosomal-dominant manner. We report an exceptionally rare case of a ruptured parietal arteriovenous malformation (AVM) situated immediately beneat…
  pubmed Umehara T, Kiyokawa H, Yamada S, Yano Y 等 2026 Jun 29 置信度 0.82
• Not just two roads down: a multimodality radiologic-pathologic review of ureteral diseases.
  Ureteral diseases encompass a broad spectrum of congenital, inflammatory, obstructive, neoplastic, and iatrogenic conditions that frequently pose diagnostic challenges in daily radiologic practice. Computed tomography urography (CTU) has emerged as the referen…
  pubmed Azpeitia-Hernandez J, Azpeitia Arman FJ, Lorente-Ramos RM, Leon García M 等 2026 Jun 29 置信度 0.82
• The current state of computed tomography in osteoarthritis research.
  CT has evolved into a complementary tool for three-dimensional (3-D) structural assessment in OA research. This review highlights advances across key domains of CT-based OA imaging: structural features, shape modeling, alignment, contact stress modeling, bone …
  pubmed Yoshikawa R, Boddu A, Turmezei TD, Segal NA 2026 Jul 置信度 0.82
• Microelectrode arrays enable directional stereo-EEG during kainate-mediated seizures.
  Surgical planning for drug-resistant epilepsy often relies on stereo-EEG (sEEG) recordings obtained with cylindrical ring electrodes. Prior modeling studies, including lead-field analysis, suggest that microelectrodes distributed around an sEEG-sized insulatin…
  pubmed Shores R, Medani T, Joshi A, Matthews C 等 2026 Jun 16 置信度 0.82
• Spatial immune archetypes in gastric and colorectal cancer: a proposed conceptual framework for immunotherapy resistance and therapeutic remodeling.
  Gastric and colorectal cancers are leading causes of global cancer mortality, yet the transformative benefits of immune checkpoint blockade remain largely confined to the small fraction of patients with MSI-H/dMMR tumors. The vast majority-those with MSS/pMMR …
  pubmed Sun S, Zeng Y, Chen J, Zhong Y 等 2026 置信度 0.82
• Integrating artificial intelligence and multi-omics data for precision oncology in endometrial cancer: a narrative review.
  Endometrial cancer (EC) is the most common gynaecological malignancy worldwide, yet the prognosis for advanced and recurrent disease remains poor, highlighting the need for improved diagnostic, prognostic, and therapeutic decision-making frameworks. Convention…
  pubmed Mondal O, Khatun M, Lawarde A, S SL 等 2026 Jun 29 置信度 0.82
• Explainable and clinically audited hybrid self-supervised framework for multi-class DFU classification and mobile deployment.
  Accurate and explainable classification of diabetic foot ulcers (DFUs) is vital for early intervention and patient management. This paper presents a Clinically Audited Hybrid Self-Supervised Framework integrating domain-adaptive SimCLR pretraining, a U-Net-bas…
  pubmed Abdullah A, Ather MA, Fatima Z, Rodríguez JLO 等 2026 Jun 28 置信度 0.82
• VIT-MBRT, a GPU accelerated Monte Carlo tool for investigations on preclinical minibeam radiation therapy.
  Minibeam Radiation Therapy (MBRT) is a form of spatially fractionated radiation therapy (SFRT) with electrons, protons, ions or kilovoltage photon beams, aiming to improve the therapeutic window compared to broad-beam irradiation. MBRT with X-rays uses an orth…
  pubmed Luongo N, Crimaldi U, Cerbone LA, Jia X 等 2026 Aug 置信度 0.82
• Overlapping bone transport as a bone-preserving docking strategy for a massive wedge-shaped infected tibial defect: a case report highlighting a selected reconstructive strategy.
  Large infected tibial defects remain amongst the most challenging problems in limb reconstruction, particularly when the defect is wedge-shaped rather than purely segmental. In such cases, conventional docking may require resection of irregular but viable cort…
  pubmed Nozaka K, Chida S, Miyakoshi N 2026 Jun 26 置信度 0.82
• Amino acid metabolic reprogramming in immunotherapy for hepatocellular carcinoma: Adaptive resistance, patient stratification, and longitudinal monitoring.
  Immunotherapy has become an important component of systemic treatment for advanced hepatocellular carcinoma (HCC), yet durable benefit remains limited to a subset of patients because of marked response heterogeneity and acquired resistance.
  pubmed He H, Qiao Z, Gai X, Ji G 等 2026 Jun 26 置信度 0.82
• Theoretical Terahertz Spectroscopy of Aqueous Solutions: From Electronic Structure to Molecular Understanding.
  Understanding the aqueous solvation of simple ions, small molecules, and complex biopolymers is fundamental in the physical and life sciences. Terahertz spectroscopy allows one to directly interrogate the underlying collective hydrogen-bond network dynamics by…
  pubmed Schienbein P, Marx D 2026 Jul 8 置信度 0.82
• EEG Revisited-Neuronal, Glial, and Network Mechanisms Across Scales.
  Electroencephalography (EEG) has been providing a window into human brain activity for nearly a century, yet its interpretation often remains empirical rather than mechanistic. This review revisits the cellular and biophysical foundations of EEG through a mode…
  pubmed Kudlacek J, Lisgaras CP, Jefferys JGR, de Curtis M 等 2026 Apr 20 置信度 0.82
• Prognostic Value of Spatial and Topological Features of Tumor Microenvironment in Classic Hodgkin Lymphoma.
  Classic Hodgkin lymphoma (CHL) constitutes a B-cell malignant lymphoid neoplasm derived from the germinal center. Despite current treatment protocols based on chemotherapy, radiotherapy, anti-cluster of differentiation (CD) 30 antibody-drug conjugates, immunot…
  pubmed Bernal-Florindo I, Raposo-Puglia JA, Ruiz FA, Perez-Requena J 等 2026 置信度 0.82
• Coronary Computed Tomography Angiography for the Diagnosis and Revascularization Guidance of Coronary Bifurcation Lesions: A Contemporary Review.
  Background : Coronary bifurcation lesions represent one of the most technically demanding scenarios in coronary artery disease (CAD), associated with higher procedural complexity, restenosis, and periprocedural complications. Recent advances in coronary comput…
  pubmed Mileva N, Vassilev D, Panayotov P, Golebiewski S 等 2026 Jun 12 置信度 0.82
• From Molecular Visualization to Spatial Landscapes: Engineering the Next Generation of In Situ Hybridization.
  In situ hybridization (ISH) has undergone a rapid evolution from a low-throughput histological staining technique to a diverse family of modern methods for sensitive, specific and multiplexed molecular detection in intact cells and tissues, and to a cornerston…
  pubmed Li Z, Luo M, Zhu M, Bai Y 2026 May 29 置信度 0.82
• Progress in the Application of Machine Learning in the Field of Single-Cell and Spatial Transcriptomics.
  The rapid evolution of transcriptome sequencing technologies has driven significant breakthroughs across the life sciences. The advent of single-cell RNA-sequencing (scRNA-seq) has enabled gene expression profiling at single-cell resolution, whereas spatial tr…
  pubmed Zhu Y, Hao Z, Zhu L, Shen L 等 2026 May 26 置信度 0.82
• Toward a Conceptual Multiscale Framework for Predictive Radiobiology: Integrating Genomic Damage, Network Rewiring, and Tissue Microenvironment.
  Radiation-induced biological responses emerge through complex interactions across multiple biological scales, ranging from molecular damage to tissue remodeling and organism-level outcomes. Although traditional radiobiology has primarily focused on DNA damage …
  pubmed Son TG 2026 Jun 9 置信度 0.82
• Graph Neural Networks for Medical Imaging Analysis and Biological Data: Integrating Topology, Geometry, Radiomics, and Generative AI.
  Graph neural networks (GNNs) are increasingly used for medical imaging analysis and biological data modeling, where the integration of radiomics, topology, geometry, and generative artificial intelligence (AI) may improve representation learning from medical i…
  pubmed Singh Y, Himeur Y, Farrelly CM, Kem-Meka Tiotsop Kadzue P 等 2026 May 29 置信度 0.82
• Bone Fusion in the Cervical Spine: Where Are We Now?
  Anterior cervical discectomy and fusion (ACDF) is one of the most commonly performed surgical procedures for the treatment of cervical degenerative disease, myelopathy, radiculopathy, and segmental instability. Although clinical outcomes are generally favorabl…
  pubmed Evangelisti MC, Mazzoli A, Cabrilo I, Perale G 2026 May 25 置信度 0.82
• Three-dimensional reconstruction-assisted preoperative assessment and surgical planning for pediatric tumors with complex vascular relationships: a report of two cases.
  Pediatric abdominal tumors with complex anatomical relationships are characterized by substantial morphological heterogeneity. Although three-dimensional reconstruction is increasingly used in surgical planning, reports that define its problem-oriented role in…
  pubmed Wang K, Xia N, Wang X, Liu Y 等 2026 Jun 25 置信度 0.82
• A Cerebral Basis for Visual Discomfort and Visual Stress.
  Visual discomfort or visual stress is an uncomfortable subjective experience that occurs in response to specific visual stimuli. It affects a large proportion of the population to various degrees, disproportionately impacting those with heightened sensory sens…
  pubmed Hibbard PB, Allen P, Asher JM, Batey K 等 2026 Jun 11 置信度 0.82
• Cutaneous Thermography in Arthropathies: Quantitative Imaging, Machine Learning, and Clinical Translation.
  Arthropathies are a major global health challenge because of their high prevalence, chronic progression, and significant impact on quality of life and health systems. Therefore, prompt and accurate diagnosis is critical for slowing disease progression and impr…
  pubmed Andrei CA, Dragosloveanu S, Grigore AG, Anghel AA 等 2026 Jun 18 置信度 0.82
• Advancements in Nanomaterial-Based Biosensors for Neuropsychiatric and Neurodegenerative Diagnostics: From Biomarker Discovery to Clinical Translation.
  Nanobiosensors, with their unique physicochemical properties, are transformative tools for diagnosing and monitoring neurodegenerative diseases and mental disorders. This article systematically reviews the latest progress of nanomaterial systems and integrated…
  pubmed Li X, Han X, Han Q, He X 等 2026 Jun 5 置信度 0.82
• Magnetometry for Agriculture and Animal Systems: From Classical Sensors to Quantum-Enabled Biosensing.
  Magnetic sensors offer a physically grounded and non-invasive approach to probing biological processes that remain inaccessible to optical, electrochemical, and radio-frequency techniques in complex agricultural environments. In recent years, advances in both …
  pubmed Wang Z, Zhang X, Tang K, Wu L 等 2026 Jun 1 置信度 0.82
• Imaging-Based Spatial Transcriptomics: Data Interpretation Methods and Biomedical Applications.
  Imaging-based spatial transcriptomics has advanced from low-plex single-molecule fluorescence in situ hybridization to a diverse set of highly multiplexed platforms, with recent multimodal and pathology-compatible capabilities. Despite major differences in che…
  pubmed Li W, Zhou Y 2026 Jun 8 置信度 0.82
• Engineering immune niches: biochemical, mechanical, and spatial design principles for translational hydrogels.
  Leveraging advanced materials is an increasingly important direction in immune engineering, which aims to reprogram immune responses to treat disease. Once implanted, biomaterials rapidly become sites where immune cells assemble, interact, and collectively sha…
  pubmed Hincapie R, Marrone Mantovani O, McFaline-Figueroa J, Correa S 2026 置信度 0.82
• Natural microcosms in ecology: fulfilling the promise of model systems?
  Natural microcosms (NMs) have been proposed as model systems for ecology based on their ubiquity, ease of study and natural context. We assess whether this potential has been met by examining 824 studies of six NMs (bromeliads, moss patches, nectar microbiomes…
  pubmed Srivastava DS, Trzcinski MK, Petermann JS, Céréghino R 等 2026 Jun 25 置信度 0.82
• Multicellular ecosystems: Linking cellular diversity to tissue function and disease.
  Tissue function emerges from coordinated interactions among diverse cell populations, whereas disruption of these interactions can lead to dysfunction. Recent advances in single-cell and spatial genomics have not only cataloged cellular diversity but also reve…
  pubmed Shi Q, Tang F, Chen Y, Zhang Z 2026 Jun 24 置信度 0.82
• Immersive Three-Dimensional Visualization as a Routine Tool for Complex Congenital Cardiac Surgical Planning: A Perspective.
  Complex congenital cardiac surgery demands precise three-dimensional (3D) spatial understanding, yet preoperative planning continues to rely predominantly on two-dimensional (2D) image interpretation. Contemporary cardiac computed tomography (CT) and magnetic …
  pubmed Ganigara M, Hibino N, Cossor W, Nagpal P 2026 Jun 24 置信度 0.82
• Quantitative risk assessment of avian influenza: A scoping review.
  Avian influenza virus (AIV) continues to pose serious risks to animal and public health. Understanding its spread requires integrating ecological, agricultural, and human information. Quantitative models provide a practical way to represent these interactions,…
  pubmed Khoshbazm M, Spence K, Soltani M, Grant L 等 2026 Dec 置信度 0.82
• Advances in oral disease models: a mini-review of developments from 2015 to 2025.
  Oral diseases represent one of the most widespread global health burdens, affecting billions of people worldwide, causing pain, disability, and substantial treatment costs. Despite their prevalence, progress in prevention and therapy has been limited, in part,…
  pubmed Huang J, Le-Tran J, Kobayashi NS, Kobayashi Y 等 2026 置信度 0.82
• How mathematics anxiety relates to mathematical ability in AI agent-supported instruction: the moderating role of executive function.
  Mathematical ability is widely recognized as a core indicator of students' cognitive development and academic achievement. However, in classroom environments where artificial intelligence (AI)-supported instruction is increasingly integrated into routine teach…
  pubmed Lin G, Tang B, Niu Y, Li J 2026 Jun 23 置信度 0.82
• Frequency-domain multi-scale hybrid attention for pathological image classification.
  Pathological image classification is critical for early cancer diagnosis and precise subtyping. However, pathological images exhibit significant heterogeneity and complex textures. Existing methods often fail to fully exploit local details, while frequency-dom…
  pubmed Zhang Y, Li J, Wang Q, Zhang L 等 2026 Jun 23 置信度 0.82
• Functional and effective connectivity methods from SEEG for characterizing epileptogenic networks in refractory epilepsy: a comprehensive review and future directions.
  Brain connectivity analysis based on stereo-electroencephalography (SEEG) has been increasingly explored as a tool for studying Epileptogenic Networks and supporting therapies for Refractory Epilepsy. In this Review, we summarize recent methodologies and findi…
  pubmed Almeida J, Cunha JPS 2026 Jul 7 置信度 0.82
• Machine and deep learning for sentinel-based land use and land cover change detection: a systematic review and future outlook.
  Remote sensing has rapidly advanced with the integration of deep learning, enabling more accurate and scalable detection of land use and land cover (LULC) changes, particularly with the increasing availability of Sentinel-1 and Sentinel-2 multispectral imagery…
  pubmed Nigar A, Li Y, Jat Baloch MY, Shafi S 等 2026 Jun 23 置信度 0.82
• Redefining LiF as a Nanostructured Building Block for Interphase Engineering in Lithium Metal Batteries.
  Lithium metal batteries (LMBs) are regarded as promising next-generation energy storage systems due to their high theoretical capacity and low reduction potential. However, their practical application is fundamentally limited by the instability of the solid el…
  pubmed Kim G, Cha J 2026 Jul 置信度 0.82
• Acute Non-Traumatic Urinary Tract Emergencies: The Central Role of CT Imaging and the Emerging Role of Photon-Counting CT.
  Acute non-traumatic urinary tract emergencies are a frequent cause of emergency department presentation and may result in significant morbidity if not promptly diagnosed. Imaging plays a pivotal role in identifying the underlying pathology, assessing disease s…
  pubmed Scaglione M, Masala SA, Di Grezia G, Tiralongo F 等 2026 Jun 23 置信度 0.82
• MammoDenseSegNet: A Context-Aware Deep Learning Model for Dense Tissue Segmentation in Digital Mammograms.
  Breast density is a breast cancer risk factor. The accurate quantification of breast density requires reliable segmentation of dense tissue in mammograms, but it is a challenging task due to large variations in tissue appearance across hospitals and imaging de…
  pubmed Ganjee R, Bandos A, Hossain MB, Mustafaev T 等 2026 Jun 22 置信度 0.82
• Photon Counting CT in Abdominal Emergency Radiology.
  Photon counting computed tomography offers spectral capabilities on every scan, significant radiation exposure reductions with improved image quality, and improved spatial resolution. Spectral reconstructions, such as iodine maps and virtual non-contrast image…
  pubmed Parrott D, Dane B 2026 Jun 22 置信度 0.82
• An Intelligence-Based Hybrid CNN-GAT Framework Optimized by the Whale Optimization Algorithm for Clinical Lung Cancer Classification from Chest CT Images.
  Early and accurate detection of lung cancer remains a central challenge in intelligence-based medicine, where robust imaging informatics solutions are required to interpret complex chest CT data. This study proposes a novel hybrid convolutional neural network-…
  pubmed Mirzaei A, Mohajerzadeh A, Nouri-Moghaddam B, Yaghoobi M 等 2026 Jun 22 置信度 0.82
• Machine Learning Optimization Algorithms for Clustering Regions and Emergency Management: A Review.
  Disasters, public health emergencies, and allied humanitarian logistical problems have continued to plague humans for years. In recent years, however, there has been a tremendous increase in the frequency of occurrence of these events. The depot location-alloc…
  pubmed Akwafuo S, Fnu P, Quezada D 2026 置信度 0.82
• Toward transferable models for efficient spatiotemporal flood prediction across coastal-estuarine systems.
  This perspective examines the application of transfer learning (TL) within deep learning (DL) frameworks for extreme water level (EWL) and spatiotemporal flood predictions. We discuss the main advantages of TL, such as enabling model transferability of pretrai…
  pubmed Daramola S, Muñoz DF, Shen C 2026 置信度 0.82
• Integrating In silico perturbation with multilayer omics to decode regulatory networks in cancer immunity: a new frontier in precision oncology.
  The traditional paradigm of linking single genes to individual phenotypes is being replaced by a systems-level framework to understand the complexity of the tumor microenvironment. In this context, in silico knockout has emerged as a powerful computational app…
  pubmed Chen H, Chen Z, Sun M, Liang L 2026 置信度 0.82
• Biology-informed risk stratification of glioblastoma by integrating MRI-based intratumoral heterogeneity with clinical features: a multicenter validation study.
  Refined risk stratification before randomization is clinically important for reducing prognostic imbalance across study arms when evaluating novel therapies for glioblastoma. However, current artificial intelligence-assisted prognostic models are often limited…
  pubmed Zhang J, Guo H, Ma X, Zhong Y 等 2026 Jun 21 置信度 0.82
• Robot-Assisted versus non-robotic frame-based deep brain stimulation: a systematic review and meta-analysis of targeting accuracy and clinical outcomes.
  Deep brain stimulation (DBS) outcomes depend on accurate lead placement. Robot-assisted DBS (RA-DBS) has been increasingly adopted, yet its advantages over conventional non-robotic frame-based DBS (NRA-DBS) regarding targeting accuracy, operative efficiency, a…
  pubmed Liu J, Sun Y, Liu M, Huo J 等 2026 Jun 22 置信度 0.82
• Fine-grained lung cancer object detection via dilated reparameterization and explicit positional gating optimization.
  Early detection and precise fine-grained radiologic classification of lung cancer are crucial for formulating clinical treatment plans. However, existing computer-aided diagnosis (CAD) systems are mostly limited to binary nodule classification or treat radiolo…
  pubmed Wu Y, He Z, Zhang S, Liang C 等 2026 Jun 20 置信度 0.82
• Machine Learning in Nonhuman Primate Models of Infectious Diseases: Current Applications and Future Perspectives.
  The amount of biologic data produced by biomedical research has increased significantly in both volume and complexity in recent years. Advances in computational power have increasingly enabled the use of machine learning (ML) to analyze and predict patterns fr…
  pubmed Koo BS, Nederlof RA, Jeon E, Bae GS 等 2026 Jun 1 置信度 0.82
• Deep Learning in Dental Imaging: Advances, Challenges, and Future.
  Artificial intelligence and deep learning have expanded dental imaging analysis by enabling automated detection, classification, localization, segmentation, and tooth identification in routinely acquired radiographs. This review provides a practice-oriented sy…
  pubmed Aydin E, Can Z 2026 Jun 19 置信度 0.82
• Quasicontinuum descriptions of rarefaction and dispersive shock waves in Fermi-Pasta-Ulam lattices with Hertzian potentials.
  In the present work, we review two well-established quasicontinuum models of a Fermi-Pasta-Ulam lattice with Hertzian potentials, and we utilize these two models to approximate the discrete dispersive shock waves which are numerically observed in the simulatio…
  pubmed Yang S 2026 May 置信度 0.82
• Automating pollinator identification using artificial intelligence and participatory science.
  Understanding the causes, consequences, and solutions to global pollinator decline will require more extensive and intensive monitoring programs. However, species-level identification remains a major challenge because of the difficulty of scaling manual identi…
  pubmed Spiesman BJ 2026 Oct 置信度 0.82
• [Engineering of an auxiliary device for intraoral scanning of edentulous jaws with dental implants].
  To develop a prototype design of a universal auxiliary geometric device (AGD) for intraoral scanning of edentulous jaws with dental implants, based on the analysis of existing solutions, and to integrate it into a CAD/CAM workflow.
  pubmed Losev FF, Borovsky LB, Kotik MS 2026 置信度 0.82
• Deep Learning for Brain Tumour Analysis: A Systematic Review of CNN-Transformer Hybrids in Multimodal Imaging.
  Brain tumour detection and analysis using medical imaging requires the extraction of both local spatial features and global contextual representations. Although convolutional neural networks (CNNs) excel at capturing local spatial patterns and Transformer-base…
  pubmed Antwi SB, Appiahene P, Ayawli BBK, Nimbe P 2026 置信度 0.82
• Operando microscopy for neuromorphic hardware.
  Microscopy techniques can uncover the physical properties and dynamic behaviours of materials, driving the discovery of emergent phenomena and guiding the design of next-generation computing hardware. As artificial intelligence becomes pervasive, the demand fo…
  pubmed Zhu Y, Frano A, Ramanathan S 2026 Jul 置信度 0.82
• Deciphering viral infections at single-cell resolution: From immune dynamics to host-pathogen interactions.
  Single-cell RNA sequencing (scRNA-seq) has emerged as a transformative technology in infectious disease research, enabling high-resolution characterization of cellular heterogeneity, immune dynamics, and host-pathogen interactions at the single-cell level. In …
  pubmed Zhou W, Xu P 2026 Sep 置信度 0.82
• Understanding community and health system acceptability, readiness and perspectives on the introduction of new vector control approaches for malaria control in Papua New Guinea.
  Malaria remains a major public health challenge in Papua New Guinea (PNG) and accounted for most malaria cases and deaths in the Western Pacific Region in 2023. Despite current national efforts centred on insecticide treated nets (ITNs), there is a pressing ne…
  pubmed Kerry Z, Farquhar R, Manuv K, Auwun A 等 2026 Jun 16 置信度 0.82
• Spatial Visual Proteomics: Insights into Tumor Microenvironment Dynamics.
  The tumor microenvironment, a dynamic network of cancer, immune, stromal, and extracellular matrix components, dictates tumor progression and therapeutic resistance. Traditional proteomics, while informative, homogenizes tissues, obscuring the spatial context …
  pubmed Huang P, Fu C, Kong Q, Tian R 2026 Jun 16 置信度 0.82
• Scalable networks of multimodal haptic arrays for plantar sensory substitution.
  Feet provide essential sensory input, supporting body awareness for safe movement. The impairment of plantar sensation, arising in conditions such as stroke and spinal cord injury, has a major impact on mobility, balance, and quality of life. Substituting the …
  pubmed Flavin MT, Huang YT, Simatos D, Hua R 等 2026 Jun 23 置信度 0.82
• Nuclear Enlargement as a Histological Hallmark of Skeletal Muscle Aging, Revealed by Deep Learning-Driven Analysis and Validated in Inflammatory Myopathies.
  Aging reshapes the architecture of human skeletal muscle, yet objective tissue-level markers that capture this process remain limited. We combined large-scale histology with deep learning to identify reproducible features of muscle aging and to test their biol…
  pubmed Dao T, Nguyen TT, Hoang GM, Park J 等 2026 Jun 置信度 0.82