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Biological and pharmaceutical systems operate under extreme safety, regulatory, and precision constraints — involving complex multi‑stage processes from genomic analysis to biologics manufacturing, from sterile processing to cold‑chain distribution. Yet today,…
datacite
Andrews, Ronald Jason
2026
置信度 0.66
DAIGSdeterministic governancebiotechnologypharmaceutical manufacturingbiologics
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Terpenoids constitute the most structurally diverse class of natural products, encompassing over eighty thousand identified compounds with critical ecological functions and profound industrial applications in pharmaceuticals, flavors, and biofuels. This extens…
datacite
biosynthesis chemistry
2026
置信度 0.66
Terpene biosynthesisMevalonate pathwayMethylerythritol phosphate pathwayMetabolic engineeringTerpene synthases
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Terpenoids constitute the most structurally diverse class of natural products, encompassing over eighty thousand identified compounds with critical ecological functions and profound industrial applications in pharmaceuticals, flavors, and biofuels. This extens…
datacite
biosynthesis chemistry
2026
置信度 0.66
Terpene biosynthesisMevalonate pathwayMethylerythritol phosphate pathwayMetabolic engineeringTerpene synthases
-
Photosynthetic microorganisms such as algae can convert sunlight into useful bioproducts, yet their efficiency drops sharply because light penetrates a shallow layer of dense cultures. Here we introduce a material-based volumetric illumination strategy that em…
datacite
Cheng, Yijie
2026
置信度 0.66
Functional materials
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The California Bioscape Siting Tool provides an interactive map interface to help users identify suitable locations for bioenergy and biomanufacturing facilities. It allows for the visualization of various data layers, analysis of siting constraints, and inven…
datacite
Huntington, Tyler
2026
置信度 0.66
bioeconomybiomassgeospatialcaliforniaagriculture
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The California Bioscape Siting Tool provides an interactive map interface to help users identify suitable locations for bioenergy and biomanufacturing facilities. It allows for the visualization of various data layers, analysis of siting constraints, and inven…
datacite
Huntington, Tyler
2026
置信度 0.66
bioeconomybiomassgeospatialcaliforniaagriculture
-
This comprehensive guide explores the synergistic relationship between systems biology and synthetic biology, two transformative disciplines reshaping biomedical research, biomanufacturing, and therapeutic development. Systems biology operates on an analytical…
datacite
synthetic biological science
2026
置信度 0.66
systems biologysynthetic biologymulti-omicscomputational modelingDBTL cycle
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This comprehensive guide explores the synergistic relationship between systems biology and synthetic biology, two transformative disciplines reshaping biomedical research, biomanufacturing, and therapeutic development. Systems biology operates on an analytical…
datacite
synthetic biological science
2026
置信度 0.66
systems biologysynthetic biologymulti-omicscomputational modelingDBTL cycle
-
Natural killer cell-derived extracellular vesicles (NK-EVs) represent a promising new dual-class of cancer immunotherapeutics, combining the intrinsic cytotoxicity of NK cells and their immunomodulatory function with the advantages of a cell-free nanovesicle s…
datacite
St-Denis-Bissonnette, Frederic
2026
置信度 0.66
Extracellular Vesicle (EV)ExosomeNatural Killer (NK)TherapeuticTriple-Negative Breast Cancer (TNBC)
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This article provides a comprehensive overview of molecular recognition as the core principle governing the function, specificity, and sensitivity of biosensors. It details the various biological recognition elements (BREs) that form the heart of these devices…
datacite
biosensor science
2026
置信度 0.66
molecular recognitionbiosensorsbiological recognition elementsaptamerstransduction
-
This article provides a comprehensive overview of molecular recognition as the core principle governing the function, specificity, and sensitivity of biosensors. It details the various biological recognition elements (BREs) that form the heart of these devices…
datacite
biosensor science
2026
置信度 0.66
molecular recognitionbiosensorsbiological recognition elementsaptamerstransduction
-
For a scheduling tool to be acceptable and effective in biopharmaceutical manufacturing it must embrace the richness of constraints that exist in the biomanufacturing floor. It must also provide a way to quickly develop and modify feasible schedules. This pape…
datacite
Siletti, Charles, Petridis, Dimitris, Koulouris, Alexandros
2007
置信度 0.66
Έλεγχος παραγωγήςProduction controlBiopharmaceutical manufacturingΒιοφαρμακευτική βιομηχανίαΕργαλεία έρευνας
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Bottlenecks are everywhere, from the freeway overpass during the morning commute to the long lines at the supermarket. But bottlenecks in a manufacturing process are bad for business. Computer models can help you eliminate those conditions or situations that r…
datacite
Petridis, Dimitris, Koulouris, Alexandros, Siletti, Charles
2002
置信度 0.66
ΑποσυμφόρησηΠροσομοιωτές επεξεργασίαςProcess simulatorsDebottleneckingBiomanufacturing facilities
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This is the Supporting Information for a preprint which will be hosted on VeriXiv. Here is the abstract, below: Current trends in carbon capture technologies suggest that recycling of carbon dioxide will be a critical lever for reversing over a century’s worth…
datacite
Li, Jeffrey, Harrigan, Patrick, Pedevillano, Paul, Lin, Myat 等
2025
置信度 0.66
Industrial microbiology (incl. biofeedstocks)FermentationBioprocessing, bioproduction and bioproductsGenomics and transcriptomics
-
Biomanufacturing has long been attractive for Mars missions due to its potential flexibility—biology can produce everything from building materials to therapeutics. However, the sheer number of possible bioproducts has created decision paralysis and made it di…
datacite
Labs Reports, Pioneer
2025
置信度 0.66
Microbial geneticsSpace sciences not elsewhere classifiedMicrobiology not elsewhere classifiedSynthetic biologyGenomics
-
This article explores the role of plant tissue culture biotechnology in developing next-generation dermocosmetic products that are effective, sustainable, and ethically produced. It details how controlled in vitro cultivation of plant cells enables the product…
datacite
Fronza, Marcio, de Oliveira Guimarães, Deivis
2025
置信度 0.66
Systems biologyCell metabolismBiochemistry and cell biology not elsewhere classifiedEvolutionary biology not elsewhere classifiedPlant biology not elsewhere classified
-
As a first step toward an outdoor Mars microbe, Pioneer Labs is engineering microbes optimized for indoor biomanufacturing on Mars. To do so, we are engineering commonly used chassis organisms E. coli and B. subtilis for in situ resource utilization (ISRU) on …
datacite
Labs Reports, Pioneer
2025
置信度 0.66
Microbial geneticsMicrobiology not elsewhere classifiedSpace sciences not elsewhere classifiedGenomicsIndustrial molecular engineering of nucleic acids and proteins
-
**Abstract:** This paper details an automated system for utilizing light-responsive caged compounds to precisely control protein folding kinetics, leading to significantly improved yields in therapeutic protein production. The system leverages a novel Multi-la…
datacite
KYUNGJUN, LIM, Researcher, Freederia AI
2025
置信度 0.66
Agricultural molecular engineering of nucleic acids and proteins
-
Aedes densonucleosis virus (AeDNV) is a mosquito specific parvovirus that infects the Aedes aegypti mosquito. There is potential to develop AeDNV as a vector control agent. This work presents several different topics centered on AeDNV. In particular, the ultra…
datacite
Specht, Rachel, Wickramasinghe, Ranil, Carlson, Jon, Belfiore, Larry 等
2007
置信度 0.66
chemical engineering
-
Synthetic biology research projects typically require multi-step workflows that are difficult to automate. One recent trend in synthetic biology is to look for possible synergy with microfluidics and lab-on-a-chip technologies. A literature survey by the autho…
datacite
Ng, Wenfa
2023
置信度 0.66
Industrial biotechnology not elsewhere classifiedBiochemistry and cell biology not elsewhere classifiedIndustrial molecular engineering of nucleic acids and proteinsMicrobiology not elsewhere classified
-
Global agriculture faces critical challenges due to the overreliance on chemical pesticides, driving an urgent need for eco-friendly biopesticides and biostimulants (BioP&S). Plant-derived peptides, evolved as natural regulators of growth, development, and…
datacite
Yu, Xiaosong, Liu, Jiuer, Wang, Wei, Shen, Jinbo 等
2025
置信度 0.66
artificial intelligencebiomanufacturingbiopesticidebiostimulantpeptide
-
datacite
Filippi, Miriam
2025
置信度 0.66
-
This project reflects on a mycelium-material practice through a practice-based method exploring the developing field of biodesign, and more specifically growing design, within an industrial design context. It reflects on the current state of the mycelium-mater…
datacite
Riesel, Joshua
2026
置信度 0.66
Industrial and product design
-
Abstract: The development of cost-effective, serum-free media is critical for scalable cultivated meat production. This study used Design of Experiments (DoE) and high-throughput screening to develop "MMM1", an animal-free, serum-free medium for the C2C12 muri…
datacite
Gordon-Petrovskii, William
2026
置信度 0.66
Cell BiologyCultivated Meat
-
Especially in biomanufacturing, methods to design optimal experiments are a valuable technique to fully exploit the potential of the emerging technical possibilities that are driving experimental miniaturization and parallelization. The general objective is to…
datacite
Krausch, Niels, Barz, Tilman, Sawatzki, Annina, Gruber, Mathis 等
2019
置信度 0.66
570 Biowissenschaften; BiologieMonte Carlodesign of experimentsvariance analysismodeling
-
Mini-bioreactor systems enabling automatized operation of numerous parallel cultivations are a promising alternative to accelerate and optimize bioprocess development allowing for sophisticated cultivation experiments in high throughput. These include fed-batc…
datacite
Sawatzki, Annina, Hans, Sebastian, Narayanan, Harini, Haby, Benjamin 等
2018
置信度 0.66
570 Biowissenschaften; Biologiemini-bioreactorshigh throughput bioprocess developmentlaboratory automationbiomanufacturing
-
In bioprocess development, the host and the genetic construct for a new biomanufacturing process are selected in the early developmental stages. This decision, made at the screening scale with very limited information about the performance in larger reactors, …
datacite
Hans, Sebastian, Haby, Benjamin, Krausch, Niels, Barz, Tilman 等
2020
置信度 0.66
570 Biowissenschaften; Biologiehigh-throughput screeningrapid phenotypingmodel-based experimental designEscherichia coli
-
datacite
Herwig, Christoph, Slouka, Christoph, Neubauer, Peter, Delvigne, Frank
2021
置信度 0.66
570 Biowissenschaften; Biologiecontinuous bioprocessingmicrobial processcellular mechanismmetabolic load
-
The global expansion of biomanufacturing is currently limited by the availability of sugar-based microbial feedstocks. One-carbon feedstocks, like methanol, present an enticing alternative to sugar because they can be produced from organic waste, atmospheric c…
datacite
Kelso, Philip A.
2023
置信度 0.66
Other education not elsewhere classified
-
The global expansion of biomanufacturing is currently limited by the availability of sugar-based microbial feedstocks. One-carbon feedstocks, like methanol, present an enticing alternative to sugar because they can be produced from organic waste, atmospheric c…
datacite
Kelso, Philip A.
2023
置信度 0.66
Other education not elsewhere classified
-
Astaxanthin, a red liposoluble ketocarotenoid, holds immense value across various industries due to its potent antioxidant properties and diverse applications in the pharmaceutical, nutraceutical, cosmetic, food, and feed sectors. In recent years, biotechnolog…
datacite
Kanwugu, Osman Nabayire
2026
置信度 0.66
Synthetic biology
-
Astaxanthin, a red liposoluble ketocarotenoid, holds immense value across various industries due to its potent antioxidant properties and diverse applications in the pharmaceutical, nutraceutical, cosmetic, food, and feed sectors. In recent years, biotechnolog…
datacite
Kanwugu, Osman Nabayire
2026
置信度 0.66
Synthetic biology
-
Animal synthetic biology could improve sustainable biomanufacturing and add unique capabilities to the field of bioremediation. We introduce how insects, such as Black Soldier Flies (BSF; Hermetia illucens), that are already used commercially to process a vari…
datacite
Tepper, Kate
2026
置信度 0.66
Synthetic biology
-
Animal synthetic biology could improve sustainable biomanufacturing and add unique capabilities to the field of bioremediation. We introduce how insects, such as Black Soldier Flies (BSF; Hermetia illucens), that are already used commercially to process a vari…
datacite
Tepper, Kate
2026
置信度 0.66
Synthetic biology
-
Circular economy, predicated on the tenets of waste minimisation, valorisation and recycling, emphasises utilisation of waste as substrates to promote sustainable biomanufacturing processes. Coffee is the second largest traded commodity globally but spent coff…
datacite
Siddiqui, Sana
2025
置信度 0.66
Biocatalysis and enzyme technology
-
Circular economy, predicated on the tenets of waste minimisation, valorisation and recycling, emphasises utilisation of waste as substrates to promote sustainable biomanufacturing processes. Coffee is the second largest traded commodity globally but spent coff…
datacite
Siddiqui, Sana
2025
置信度 0.66
Biocatalysis and enzyme technology
-
Synthetic biology combines computer science, engineering, chemistry, and genetics to view genes and DNA as building blocks for engineering customised organisms. This approach allows for creating physiologically altered organisms that produce useful chemicals a…
datacite
Harrison, Fergus Stuart McDonald
2025
置信度 0.66
Synthetic biology
-
Synthetic biology combines computer science, engineering, chemistry, and genetics to view genes and DNA as building blocks for engineering customised organisms. This approach allows for creating physiologically altered organisms that produce useful chemicals a…
datacite
Harrison, Fergus Stuart McDonald
2025
置信度 0.66
Synthetic biology
-
Nature exhibits an enormous diversity of organisms that thrive in extreme environments. From snow algae that reproduce at sub-zero temperatures to radiotrophic fungi that thrive in nuclear radiation at Chernobyl, extreme organisms raise many questions about th…
datacite
Caro-Astorga, Joaquin, Meyerowitz, Joseph T, Stork, Devon A, Nattermann, Una 等
2024
置信度 0.66
Ecology,Evolution & EthologyComputational & Systems BiologyMicrofabrication & BioengineeringBiochemistry & ProteomicsStructural Biology & Biophysics
-
Nature exhibits an enormous diversity of organisms that thrive in extreme environments. From snow algae that reproduce at sub-zero temperatures to radiotrophic fungi that thrive in nuclear radiation at Chernobyl, extreme organisms raise many questions about th…
datacite
Caro-Astorga, Joaquin, Meyerowitz, Joseph T, Stork, Devon A, Nattermann, Una 等
2024
置信度 0.66
Ecology,Evolution & EthologyComputational & Systems BiologyMicrofabrication & BioengineeringBiochemistry & ProteomicsStructural Biology & Biophysics
-
As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and engineering…
datacite
Murphy, JF, Lavelle, M, Asciak, L, Burdis, R 等
2024
置信度 0.66
Tumour BiologyStem CellsSignalling & OncogenesDevelopmental BiologyHuman Biology & Physiology
-
As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging fields of biomanufacturing and biofabrication are transforming life sciences and healthcare. These sectors are benefiting from a synergy of synthetic and engineering…
datacite
Murphy, JF, Lavelle, M, Asciak, L, Burdis, R 等
2024
置信度 0.66
Tumour BiologyStem CellsSignalling & OncogenesDevelopmental BiologyHuman Biology & Physiology
-
Significant advancements in tissue engineering have enabled the creation of functional tissue constructs for applications including drug toxicity testing, disease modeling, and regenerative therapies. Central to these applications is the ability to culture suf…
datacite
Kant, Rajeev, Pyon, Stephen, Dwyer, Kiera, Snyder, Caroline 等
2026
置信度 0.66
EngineeringMedicine, Health and Life Sciences
-
A growing need for engineered tissues with complex microarchitectures has driven rapid advances in light-based biomanufacturing. High spatial resolution and biocompatibility make the photopolymerization technique particularly attractive for fabricating tissues…
datacite
Zhang, Qianyi
2026
置信度 0.66
3D printinglight-based additive manufacturinglight scatteringbioprintingwavefront shaping
-
Bionformatics bite: how to find the transcription start site of a gene -- Search box on library's website will be on top right of every page -- Exciting news for Anschutz Medical Campus faculty and staff! Free ILL! -- Clinical corner -- Want to publish in natu…
datacite
Multiple authors, Health Sciences Library
2015
置信度 0.66
Electronic newsletters
-
Bionformatics bite: how to find the transcription start site of a gene -- Search box on library's website will be on top right of every page -- Exciting news for Anschutz Medical Campus faculty and staff! Free ILL! -- Clinical corner -- Want to publish in natu…
datacite
Multiple authors, Health Sciences Library
2015
置信度 0.66
Electronic newsletters
-
Anfang März 2026 hat die Volksrepublik ihren nächsten Fünfjahresplan verabschiedet und damit die politischen und wirtschaftlichen Leitlinien für 2026 bis 2030 gesetzt. Im Fokus stehen geopolitische Resilienz und technologische Eigenständigkeit. Erstmals rückt …
datacite
Michael Laha
2026
置信度 0.66
FOS: Political science
-
COMPModelpy: Understanding Microbial Metabolism in Bioreactors by Integrating Metabolic Models in a Compartment Modeling Framework Samira L. van den Bogaard and Titania C. Sugiarto, Tobias B. Alter, and Lars M. Blank Institute of Applied Biotechnology (iAMB), …
datacite
van den Bogaard, Samira, Sugiarto, Titania Insani, Alter, Tobias Benedikt, Blank, Lars M.
2026
置信度 0.66
Compartment modelMetabolic modelingProtein Allocation Model
-
COMPModelpy: Understanding Microbial Metabolism in Bioreactors by Integrating Metabolic Models in a Compartment Modeling Framework Samira L. van den Bogaard and Titania C. Sugiarto, Tobias B. Alter, and Lars M. Blank Institute of Applied Biotechnology (iAMB), …
datacite
van den Bogaard, Samira, Sugiarto, Titania Insani, Alter, Tobias Benedikt, Blank, Lars M.
2026
置信度 0.66
Compartment modelMetabolic modelingProtein Allocation Model
-
Developments over the past few decades in metabolic engineering and synthetic biology hold great promise for fueling a robust bioeconomy, in which microbial biomanufacturing platforms can be utilized to produce an array of industrial and pharmaceutically impor…
datacite
Brooks, Sierra Mckenna
2023
置信度 0.66
Engineered living materialsSynthetic biologyMetabolic engineering
-
🧬 Whole Genome Assembly of 5 Streptococcus iniae bacteria isolated from diseased Asian Seabass, Thailand, comparative genomics, validation of WGS and in-sillico identification of antigens for vaccine biomanufacturing via Quality by Design (QbD). Organism: Str…
datacite
ANDRES, Quentin Ludovic Stephane, Srikulnath, Kornsorn, Singchat, Worapong, Srisapoome, Prapansak
2026
置信度 0.66
-
Artificial intelligence has catalyzed a paradigm shift in protein science, transforming our ability to predict protein structures, design novel proteins, and develop next-generation biopharmaceuticals. This review synthesizes recent breakthroughs in AI-driven …
datacite
Nan, Yutong
2026
置信度 0.66
-
Artificial intelligence has catalyzed a paradigm shift in protein science, transforming our ability to predict protein structures, design novel proteins, and develop next-generation biopharmaceuticals. This review synthesizes recent breakthroughs in AI-driven …
datacite
Nan, Yutong
2026
置信度 0.66
-
Zenodo Description – Polybiome Systems Medicine, Volume III Abstract / Overview:This White Paper presents Polybiome Systems Medicine, Volume III, a comprehensive, human-centered, and forward-looking framework integrating AI-driven nutrigenomics, precision ferm…
datacite
REYED M, REYED
2026
置信度 0.66
-
Zenodo Description – Polybiome Systems Medicine, Volume III Abstract / Overview:This White Paper presents Polybiome Systems Medicine, Volume III, a comprehensive, human-centered, and forward-looking framework integrating AI-driven nutrigenomics, precision ferm…
datacite
REYED M, REYED
2026
置信度 0.66
-
datacite
Ujjwal Sinha, Dr. Kaliprasanna Swain
2026
置信度 0.66
-
Biomolecular networks underpin emerging technologies in synthetic biology-from robust biomanufacturing and metabolic engineering to smart therapeutics and cell-based diagnostics-and also provide a mechanistic language for understanding complex dynamics in natu…
datacite
Filo, Maurice, Rossi, Nicolò, Fang, Zhou, Khammash, Mustafa
2026
置信度 0.66
Quantitative Methods (q-bio.QM)Artificial Intelligence (cs.AI)Machine Learning (cs.LG)Systems and Control (eess.SY)Molecular Networks (q-bio.MN)
-
The development of continuous biomanufacturing processes requires robust and early anomaly detection, since even minor deviations can compromise yield and stability, leading to disruptions in scheduling, reduced weekly production, and diminished economic perfo…
datacite
Kailasanathan, Rajiv, Clements, William R., Boskabadi, Mohammad Reza, Gibford, Shawn M. 等
2025
置信度 0.66
Machine Learning (cs.LG)Other Quantitative Biology (q-bio.OT)Quantum Physics (quant-ph)FOS: Computer and information sciencesFOS: Computer and information sciences
-
Living organisms rely on endogenous feedback mechanisms to maintain homeostasis in the presence of uncertainty and environmental fluctuations. An emerging challenge at the interface of control systems engineering and synthetic biology is the design of reliable…
datacite
di Bernardo, Mario
2026
置信度 0.66
Systems and Control (eess.SY)FOS: Electrical engineering, electronic engineering, information engineering
-
This Zenodo record is a permanently preserved version of a PREreview. You can view the complete PREreview at https://prereview.org/reviews/18770706. Formal Peer Review Manuscript Title: Interpretable Biomanufacturing Process Risk and Sensitivity Analyses for Q…
datacite
Lauretta Ojo
2026
置信度 0.66
-
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Clinical trials, including chimeric antigen receptor (CAR) T cell therapy for a range of terminal tumors, are now ongoing in several locations across the world, and the commercialization of some of these therapies is likely to begin in the near future. Because…
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We propose metrics for evaluating the performance of robotically assembled discrete cellular lattice structures (referred to as digital materials) by defining a set of tools used to evaluate how the assembly system impacts the achievable performance objective …
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Abstract The successful design of economically viable bioprocesses can help to abate global dependence on petroleum, increase supply chain resilience, and add value to agriculture. Specifically, bioprocessing provides the opportunity to replace petrochemical p…
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Kimia Noroozi, Laura R Jarboe
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Abstract Throughout the design process, architectural engineer of biopharmaceutical facility must be cognizant of the various global and regional regulatory statutes, related regulations, and expectations that are applicable to the facility's design, form, and…
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Kip Priesmeyer
2014-09-15T02:35:11Z
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The introduction of the Internet into the manufacturing environment is becoming a prominent trend. In this context, two important concepts concerning manufacturing, i.e. Industry 4.0 and cloud manufacturing have been proposed. Industry 4.0 refers to the fourth…
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Shape deformation is an important issue in additive manufacturing (AM) processes such as the projection-based Stereolithography. Volumetric shrinkage and thermal cooling during the photopolymerization process combined with other factors such as the layer-const…
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