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• Using Cupriavidus necator H16 to Provide a Roadmap for Increasing Electroporation Efficiency in Nonmodel Bacteria
  ACS synthetic biology (2024). doi:10.1021/acssynbio.4c00380
  datacite Vajente, Matteo, Clerici, Riccardo, Ballerstedt, Hendrik, Blank, Lars M. 等 2024 置信度 0.66 570
• AutoBioTech─A Versatile Biofoundry for Automated Strain Engineering
  ACS synthetic biology 13(7), 2227-2237 (2024). doi:10.1021/acssynbio.4c00298
  datacite Rosch, Tobias Michael, Tenhaef, Julia, Stoltmann, Tim, Redeker, Till 等 2024 置信度 0.66 570
• Euchloe bazae Fabiano 1993
  Euchloe bazae, an endemic species of the Iberian Peninsula, faces significant threats that justify its legAl clAssificAtion As “EndAngered” in the SpAnish CAtAlogue of EndAngered Species. Comprehensive conservation efforts are required to protect E. bazae as t…
  datacite Monasterio, Yeray, Lozano-Martín, Carlos, Vila, Roger, Iglesias, Arturo 等 2024 置信度 0.66 BiodiversityTaxonomyAnimaliaArthropodaInsecta
• Euchloe bazae Fabiano 1993
  Euchloe bazae, an endemic species of the Iberian Peninsula, faces significant threats that justify its legAl clAssificAtion As “EndAngered” in the SpAnish CAtAlogue of EndAngered Species. Comprehensive conservation efforts are required to protect E. bazae as t…
  datacite Monasterio, Yeray, Lozano-Martín, Carlos, Vila, Roger, Iglesias, Arturo 等 2024 置信度 0.66 BiodiversityTaxonomyAnimaliaArthropodaInsecta
• Polyp-DDPM: Diffusion-Based Semantic Polyp Synthesis for Enhanced Segmentation
  This study introduces Polyp-DDPM, a diffusion-based method for generating realistic images of polyps conditioned on masks, aimed at enhancing the segmentation of gastrointestinal (GI) tract polyps. Our approach addresses the challenges of data limitations, hig…
  datacite Dorjsembe, Zolnamar, Pao, Hsing-Kuo, Xiao, Furen 2024 置信度 0.66 Computer Vision and Pattern Recognition (cs.CV)Machine Learning (cs.LG)FOS: Computer and information sciencesFOS: Computer and information sciences
• India Tissue Engineering Market 2024 To 2033
  India Tissue Engineering Market Size, Trends and Insights By Product (Synthetic Scaffold Material, Biologically Derived Scaffold Material, Others), By Application (Orthopedics and Musculoskeletal, Neurology, Cardiovascular, Skin and Integumentary, Dental, Othe…
  datacite Sirsat, Nitin 2024 置信度 0.66 India Tissue Engineering MarketIndia Tissue Engineering Market SizeIndia Tissue Engineering Market TrendsIndia Tissue Engineering Market ShareIndia Tissue Engineering Market Report
• India Tissue Engineering Market 2024 To 2033
  India Tissue Engineering Market Size, Trends and Insights By Product (Synthetic Scaffold Material, Biologically Derived Scaffold Material, Others), By Application (Orthopedics and Musculoskeletal, Neurology, Cardiovascular, Skin and Integumentary, Dental, Othe…
  datacite Sirsat, Nitin 2024 置信度 0.66 India Tissue Engineering MarketIndia Tissue Engineering Market SizeIndia Tissue Engineering Market TrendsIndia Tissue Engineering Market ShareIndia Tissue Engineering Market Report
• Accurate RNA 3D structure prediction using a language model-based deep learning approach
  Accurate prediction of RNA three-dimensional (3D) structure remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing RNA-targeting drug development and synthetic biology design. The structural flex…
  datacite Shen, Tao, Hu, Zhihang, Sun, Siqi, Liu, Di 等 2022 置信度 0.66 Quantitative Methods (q-bio.QM)Machine Learning (cs.LG)Biomolecules (q-bio.BM)FOS: Biological sciencesFOS: Biological sciences
• Histology-informed microstructural diffusion simulations for MRI cancer characterisation (Histo-µSim): ex vivo mouse data
  The Histo-μSim diffusion MRI framework: data from fixed mouse tissue scanned ex vivo This record contains diffusion MRI and hematoxylin-eosin (HE) histological data from fixed mouse tissue, scanned ex vivo on a 9.4T system.Data have been obtained from MMTV-PyM…
  datacite Grussu, Francesco, Grigoriou, Athanasios, Macarro, Carlos, Perez-Lopez, Raquel 2024 置信度 0.66
• A Social Innovation Experiment with Artificial Intelligence. EU-LIFE UTOPIA Conference 2024 report.
  The EU-LIFE UTOPIA Conference 2024: A Social Innovation Experiment with Artificial Intelligence demonstrated the profound impact AI is poised to have on biomedicine, from enhancing cancer detection to driving the future of synthetic biology. The conference hig…
  datacite Däuble, Wolfgang 2024 置信度 0.66 Artificial IntelligenceArtificial Intelligence/ethicsbiomedicineresearch excellence
• A Social Innovation Experiment with Artificial Intelligence. EU-LIFE UTOPIA Conference 2024 report.
  The EU-LIFE UTOPIA Conference 2024: A Social Innovation Experiment with Artificial Intelligence demonstrated the profound impact AI is poised to have on biomedicine, from enhancing cancer detection to driving the future of synthetic biology. The conference hig…
  datacite Däuble, Wolfgang 2024 置信度 0.66 Artificial IntelligenceArtificial Intelligence/ethicsbiomedicineresearch excellence
• Full-Body 3D Human Gait Dataset walking on flat ground
  This dataset contains full-body 3D gait data collected from 26 healthy participants (10 males, 16 females) with an average age of 28.19 ± 7.77 years. Data was captured using the Xsens Awinda MTw inertial measurement system, comprising 17 wireless sensors opera…
  datacite Carneros Prado, David, Cabañero Gómez, Luis, Dobrescu, Constantin Cosmin, Villa, Laura 等 2024 置信度 0.66 Human gait3D motion captureXsensFlat ground walkingWalking patterns
• Full-Body 3D Human Gait Dataset walking on flat ground
  This dataset contains full-body 3D gait data collected from 26 healthy participants (10 males, 16 females) with an average age of 28.19 ± 7.77 years. Data was captured using the Xsens Awinda MTw inertial measurement system, comprising 17 wireless sensors opera…
  datacite Carneros Prado, David, Cabañero Gómez, Luis, Dobrescu, Constantin Cosmin, Villa, Laura 等 2024 置信度 0.66 Human gait3D motion captureXsensFlat ground walkingWalking patterns
• Propensity Score Alignment of Unpaired Multimodal Data
  Multimodal representation learning techniques typically rely on paired samples to learn common representations, but paired samples are challenging to collect in fields such as biology where measurement devices often destroy the samples. This paper presents an …
  datacite Xi, Johnny, Osea, Jana, Xu, Zuheng, Hartford, Jason 2024 置信度 0.66 Machine Learning (cs.LG)Methodology (stat.ME)Machine Learning (stat.ML)FOS: Computer and information sciencesFOS: Computer and information sciences
• Absorb & Escape: Overcoming Single Model Limitations in Generating Genomic Sequences
  Abstract Recent advances in immunology and synthetic biology have accelerated the development of deep generative methods for DNA sequence design. Two dominant approaches in this field are AutoRegressive (AR) models and Diffusion Models (DMs). However, genomic …
  datacite Li, Zehui, Ni, Yuhao, Xia, Guoxuan, Beardall, William 等 2024 置信度 0.66 Genomics (q-bio.GN)Artificial Intelligence (cs.AI)Machine Learning (cs.LG)FOS: Biological sciencesFOS: Biological sciences
• Two ChEMBL-34 subsets (lead-like and drug-like molecules)
  Two subsets of molecules from ChEMBL-34[1]. Those molecular datasets might be useful to people training molecular generators. After decompression, you will get:chembl34_stable_ES_OA_LL.smi: 585,272 molecules.chembl34_stable_ES_OA_DL.smi: 756,420 molecules. sta…
  datacite Berenger, Francois 2024 置信度 0.66
• Two ChEMBL-34 subsets (lead-like and drug-like molecules)
  Two subsets of molecules from ChEMBL-34[1]. Those molecular datasets might be useful to people training molecular generators. After decompression, you will get:chembl34_stable_ES_OA_LL.smi: 585,272 molecules.chembl34_stable_ES_OA_DL.smi: 756,420 molecules. sta…
  datacite Berenger, Francois 2024 置信度 0.66
• <b><i>In vitro </i></b><b>transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade</b>
  Revised dataset of Barthel et al., 2024, ' In vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade'. See abstract below. In vitro metabolic systems allow the reconstitution of natural and new-to-nature pathways outside …
  datacite Barthel, Sebastian 2024 置信度 0.66 Analytical biochemistryEnzymesSynthetic biology
• Reliable Genomic Integration Sites in Pseudomonas putida Identified by Two-Dimensional Transcriptome Analysis
  ACS synthetic biology 13(7), 2060 - 2072 (2024). doi:10.1021/acssynbio.3c00747
  datacite Köbbing, Sebastian, Lechtenberg, Thorsten, Wynands, Benedikt, Blank, Lars M. 等 2024 置信度 0.66 570
• Data for 'Estimating orientation in Natural scenes: A Spiking Neural Network Model of the Insect Central Complex' (2024)
  Data for paper published in PLOS Computational Biology (Aug 2024) Abstract The central complex of insects contains cells, organised as a ring attractor, that encode head direction. The `bump' of activity in the ring can be updated by idiothetic cues and extern…
  datacite Stentiford, Rachael, Knight, James, Nowotny, Thomas, Philippides, Andrew 等 2024 置信度 0.66 Modelling and simulation
• Data for 'Estimating orientation in Natural scenes: A Spiking Neural Network Model of the Insect Central Complex' (2024)
  Data for paper published in PLOS Computational Biology (Aug 2024) Abstract The central complex of insects contains cells, organised as a ring attractor, that encode head direction. The `bump' of activity in the ring can be updated by idiothetic cues and extern…
  datacite Stentiford, Rachael, Knight, James, Nowotny, Thomas, Philippides, Andrew 等 2024 置信度 0.66 Modelling and simulation
• RNA Triplet Repeats: Improved Algorithms for Structure Prediction and Interactions
  RNAs composed of Triplet Repeats (TR) have recently attracted much attention in the field of synthetic biology. We study the mimimum free energy (MFE) secondary structures of such RNAs and give improved algorithms to compute the MFE and the partition function.…
  datacite Boehmer, Kimon, Berkemer, Sarah J., Will, Sebastian, Ponty, Yann 2024 置信度 0.66 RNA foldingRNA interactionstriplet repeatsdynamic programmingNP-hardness
• Optimization of an in-house bacterial cell-free expression system to evaluate the design of toehold switch sensors for selected cervical precancer miRNA biomarkers
  Cervical cancer is a significant health burden for women across the globe. However, over 94% of all cervical deaths occured in low and middle income countries (LMICs) in 2022 alone. This reflects a broader trend of a lack of access to quality treatment options…
  datacite Meyer, Jonathon 2024 置信度 0.66
• Reliable Genomic Integration Sites in Pseudomonas putida Identified by Two-Dimensional Transcriptome Analysis
  ACS synthetic biology 13(7), 2060-2072 (2024). doi:10.1021/acssynbio.3c00747
  datacite Köbbing, Sebastian, Lechtenberg, Thorsten, Wynands, Benedikt Niklas Daniel, Blank, Lars M. 等 2024 置信度 0.66 570
• Always, everywhere Gasoreceptor is present
  Adam Mickiewicz University scientist challenges the 2019 Nobel Prize in Medicine and Physiology discovery regarding oxygen sensing and adaptation in cells. He proposes yet to be discovered oxygen gasoreceptors that function upstream of the proteins in the Nobe…
  datacite Anbalagan, Savani 2024 置信度 0.66 gasoreceptorgasocrineoxygen
• Always, everywhere Gasoreceptor is present
  Adam Mickiewicz University scientist challenges the 2019 Nobel Prize in Medicine and Physiology discovery regarding oxygen sensing and adaptation in cells. He proposes yet to be discovered oxygen gasoreceptors that function upstream of the proteins in the Nobe…
  datacite Anbalagan, Savani 2024 置信度 0.66 gasoreceptorgasocrineoxygen
• In Gasocrine We Trust
  Adam Mickiewicz University scientist proposes a new concept in biology that may unite researchers from diverse scientific backgrounds. His proposal of gasocrinology is equivalent to Newton’s gravity but for gas-based interactions between and within organisms a…
  datacite Anbalagan, Savani 2024 置信度 0.66 gasocrinegasoreceptoroxygengasocrinologyclimate change
• In Gasocrine We Trust
  Adam Mickiewicz University scientist proposes a new concept in biology that may unite researchers from diverse scientific backgrounds. His proposal of gasocrinology is equivalent to Newton’s gravity but for gas-based interactions between and within organisms a…
  datacite Anbalagan, Savani 2024 置信度 0.66 gasocrinegasoreceptoroxygengasocrinologyclimate change
• The LAVA mutants defective in auxin-regulated primary or lateral root development.
  Regulation of PIN activity, polarity as well as auxin gradient generation and its canalisation remain crucial topics in plant developmental biology especially in the context of organogenesis like the formation new lateral roots. Here, we are presenting the LAV…
  datacite Medvecká, Eva, Sans Sánchez, Adria, Pukyšová, Vendula, Rýdza, Nikola 等 2024 置信度 0.66 AuxinAuxin SignallingLR organogenesissubcellular traffickingcanalisation
• The LAVA mutants defective in auxin-regulated primary or lateral root development.
  Regulation of PIN activity, polarity as well as auxin gradient generation and its canalisation remain crucial topics in plant developmental biology especially in the context of organogenesis like the formation new lateral roots. Here, we are presenting the LAV…
  datacite Medvecká, Eva, Sans Sánchez, Adria, Pukyšová, Vendula, Rýdza, Nikola 等 2024 置信度 0.66 AuxinAuxin SignallingLR organogenesissubcellular traffickingcanalisation
• AutoBioTech─A Versatile Biofoundry for Automated Strain Engineering
  ACS synthetic biology 13(7), 2227 - 2237 (2024). doi:10.1021/acssynbio.4c00298
  datacite Rosch, Tobias Michael, Tenhaef, Julia, Stoltmann, Tim, Redeker, Till 等 2024 置信度 0.66 570
• 2024_Diosdi_ tumour-stroma_spheroid_multicultures_dataset
  ARTICLE (when using these files, please, cite the following article): Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• Maximum_Intensity_Projection_images_and_masks
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• Maximum_Intensity_Projection_images_and_masks
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• Tumour-stroma_spheroid_multicultures_features
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_96h_dox
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_96h_dox
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_48h_dox
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_48h_dox
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_24h_dox
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_24h_dox
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_96h
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_96h
  ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluorescence 3D images of tumour-s…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_48h
  10.6084/m9.figshare.c.7357135ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluor…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_48h
  10.6084/m9.figshare.c.7357135ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluor…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_24h
  10.6084/m9.figshare.c.7357135ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluor…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• MG-63_24h
  10.6084/m9.figshare.c.7357135ARTICLE (when using these files, please, cite the following article):Akos Diosdi, Filippo Piccinini, Timea Boroczky, Gabriella Dobra, Gastone Castellani, Krisztina Buzas, Peter Horvath, Maria Harmati. "Single-cell light-sheet fluor…
  datacite Piccinini, Filippo, Diosdi, Akos 2024 置信度 0.66 Cell development, proliferation and death
• Actin-membrane linkers: Insights from synthetic reconstituted systems
  crossref Feng-Ching Tsai, Gwendal Guérin, Julien Pernier, Patricia Bassereau 2024-03-01T16:30:17Z 置信度 0.70
• <i>De novo</i> RNA base editing in plant organelles with engineered synthetic P-type PPR editing factors
  ABSTRACT In plant mitochondria and chloroplasts, cytidine-to-uridine RNA editing plays a crucial role in regulating gene expression. While natural PLS-type PPR proteins are specialized in this process, synthetic PPR proteins offer significant potential for tar…
  crossref Sébastien Mathieu, Elena Lesch, Shahinez Garcia, Graindorge Stéfanie 等 2024-09-20T09:40:15Z 置信度 0.70
• Darwinian Evolution of Self-Replicating DNA in a Synthetic Protocell
  ABSTRACT Replication, heredity, and evolution are characteristic of Life. We and others have postulated that the reconstruction of a synthetic living system in the laboratory will be contingent on the development of a genetic self-replicator capable of undergo…
  crossref Zhanar Abil, Ana María Restrepo Sierra, Andreea R. Stan, Amélie Châne 等 2024-05-01T01:15:30Z 置信度 0.70
• Growing Long-chain Polymers in vitro Using Engineered Bacteria in Synthetic Biology and Precision Fermentation Space
  The synthesis of long-chain polymers has a conventional method of utilizing energy-intensive chemical procedures, which are normally not eco-friendly. Though synthesizing polymers using synthetic biology and precision fermentation is not possible in vitro, bot…
  crossref Pranav Bhaskar 2025-05-20T19:04:01Z 置信度 0.70
• Synthetic-biology approach for plant lignocellulose engineering
  crossref Kouki Yoshida, Shingo Sakamoto, Nobutaka Mitsuda 2024-09-11T18:11:44Z 置信度 0.70
• When synthetic biology meets medicine
  Abstract In recent years, the world has faced significant challenges with the coronavirus disease 2019 (COVID-19) pandemic, as well as other infectious diseases such as Zika and Ebola. Furthermore, the rapid rise of non-communicable diseases such as diabetes, …
  crossref Yuge Feng, Cong Su, Guobin Mao, Baoting Sun 等 2024-03-06T18:38:04Z 置信度 0.70
• Compartmentalized Terpenoid Production in Plants Using Agrobacterium-Mediated Transient Expression
  crossref Jacob D. Bibik, Abigail E. Bryson, Björn Hamberger 2024-03-11T22:02:42Z 置信度 0.70
• AuxSynBio: synthetic biology tools to understand and engineer auxin
  crossref Britney L Moss 2024-09-09T15:22:36Z 置信度 0.70
• The Next Emergence of Synthetic Biology
  crossref Hana El-Samad 2024-02-16T09:59:15Z 置信度 0.70
• Navigating directed evolution efficiently: optimizing selection conditions and selection output analysis
  Abstract Directed evolution is a powerful tool that can bypass gaps in our understanding of the sequence-function relationship of proteins and still isolate variants with desired activities, properties, and substrate specificities. The rise of directed evoluti…
  crossref Paola Handal-Marquez, Hoai Nguyen, Vitor B. Pinheiro 2024-05-24T00:20:20Z 置信度 0.70
• Genome-Wide Screen for Enhanced Noncanonical Amino Acid Incorporation in Yeast
  crossref Briana R. Lino, James A. Van Deventer 2024-03-11T22:02:42Z 置信度 0.70
• novoStoic2.0: An integrated framework for pathway synthesis, thermodynamic evaluation, and enzyme selection
  Abstract Computational pathway design and retro-biosynthetic approaches can facilitate the development of innovative biochemical production routes, biodegradation strategies, and the funneling of multiple precursors into a single bioproduct. However, effective…
  crossref Vikas Upadhyay, Mohit Anand, Costas D. Maranas 2024-09-29T00:30:13Z 置信度 0.70
• A geometrically controlled post-translational oscillator for synthetic biology
  crossref Jonathan A. Fischer, Margaret E. Johnson 2024-02-08T13:10:16Z 置信度 0.70
• Abstract IA010: Targeting genome instability in cancer: Translating synthetic lethal biology into the clinic
  Abstract Membrane-associated tyrosine- and threonine-specific Cdc2-inhibitory kinase (PKMYT1) is a cell cycle regulatory kinase that inhibits CDK1/CyclinB activity, delaying entry into mitosis in tumor cells experiencing replication stress (RS). RS is frequent…
  crossref Michael Zinda 2024-06-10T07:08:38Z 置信度 0.70
• METABOLIC PLASTICITY OF AQUATIC PLANT PROVIDE NEW MODELS FOR SYNTHETIC BIOLOGY
  crossref 2024-12-12T09:38:42Z 置信度 0.70
• Synthetic Biology-Enabled Engineering of Probiotics for Precision and Targeted Therapeutic Delivery Applications
  Probiotics, defined as live microorganisms that offer health benefits when consumed in adequate amounts, have traditionally been used to maintain gastrointestinal (GI) health. They are effective in managing conditions such as inflammatory bowel disease (IBD), …
  crossref Debtosh Patra 2024-11-17T10:20:42Z 置信度 0.70
• On the path to generate electricity from wastewater through genetic engineering of <i>Escherichia coli</i>
  crossref Charlotte Ayn Cialek 2024-01-16T10:53:03Z 置信度 0.70
• An Improved Method for Eliminating or Creating Intragenic Bacterial Promoters
  crossref Ellina Trofimova, Dominic Y. Logel, Paul R. Jaschke 2024-03-11T22:02:42Z 置信度 0.70
• Genetically engineered synthetic cells activate cargo release upon temperature shift
  crossref 2024-07-25T10:03:04Z 置信度 0.70
• Synthetic Genomics: Repurposing Biological Systems for Applications in Engineering Biology
  Substantial improvements in DNA sequencing and synthesis technologies and increased understanding of genome biology have empowered the development of synthetic genomics. The ability to design and construct engineered living cells boosted up by synthetic chromo…
  pubmed Xian Fu, Yue Shen, Fu X, Shen Y 2024 May 17 置信度 0.82
• Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue
  Abstract Early-after depolarizations (EADs) are changes in the action potential plateau that can lead to cardiac arrhythmia. At the cellular level, these oscillations are irregular and change from beat to beat due to the sensitivity of voltage repolarization t…
  crossref Jack Stein, D’Artagnan Greene, Flavio Fenton, Yohannes Shiferaw 2024-11-14T21:55:12Z 置信度 0.70
• Implementation of Biosecurity Measures in Different Settings
  crossref Leyma Pérez, De Haro 2024-08-08T18:41:23Z 置信度 0.70
• Protein recruitment to dynamic DNA-RNA host condensates
  Abstract We describe the design and characterization of artificial nucleic acid condensates that are engineered to recruit and locally concentrate proteins of interest in vitro . These condensates emerge from the programmed interactions of nanostructured motif…
  crossref Mahdi Dizani, Daniela Sorrentino, Siddharth Agarwal, Jaimie Marie Stewart 等 2024-06-05T01:10:32Z 置信度 0.70
• Rapidly inducible yeast surface display for antibody evolution with OrthoRep
  Abstract We recently developed ‘autonomous hypermutation yeast surface display’ (AHEAD), a technology that enables the rapid generation of potent and specific antibodies in yeast. AHEAD pairs yeast surface display with an error-prone orthogonal DNA replication…
  crossref Alexandra M. Paulk, Rory L. Williams, Chang C. Liu 2024-05-25T01:20:12Z 置信度 0.70
• Biochemical implementation of acceleration sensing and PIDA control
  Abstract Designing dependable, self-regulated biochemical systems has long posed a challenge in the field of Synthetic Biology. Here, we propose a realization of a Proportional-Integral-Derivative-Acceleration (PIDA) control scheme as a Chemical Reaction Netwo…
  crossref Emmanouil Alexis, Sebastián Espinel-Ríos, Ioannis G. Kevrekidis, José L. Avalos 2024-07-03T00:05:21Z 置信度 0.70
• 14 To the Planets and Beyond: Synthetic Biology in Space
  crossref 2023-08-16T21:31:21Z 置信度 0.70
• <i>Synthetic Biology</i>: fostering the cyber-biological revolution
  crossref Jean Peccoud 2016-06-15T22:09:27Z 置信度 0.70
• Plant synthetic genomics: Big lessons from the little yeast
  crossref Hao Ye, Guangyu Luo, Zhenwu Zheng, Xiaofang Li 等 2024-08-29T11:24:49Z 置信度 0.70
• Advancing Sustainable Agriculture: Next-Generation Biofertilizers through Synthetic Biology and Nanoparticle Integration
  crossref Gagan Singh Guru, Chiranjeev Pandey 2024-09-23T13:29:48Z 置信度 0.70
• Construction of Xylose-Utilizing Cyanobacterial Chassis for Bioproduction Under Photomixotrophic Conditions
  crossref Xinyu Song, Yue Ju, Lei Chen, Weiwen Zhang 2024-03-11T22:02:42Z 置信度 0.70
• Genetic Network Design Automation with LOICA
  crossref Gonzalo Vidal, Carolus Vitalis, Tamara Matúte, Isaac Núñez 等 2024-03-11T22:02:42Z 置信度 0.70
• Positive Selection Screens for Programmable Endonuclease Activity Using I-SceI
  crossref Michael A. Mechikoff, Kok Zhi Lee, Kevin V. Solomon 2024-03-11T22:02:42Z 置信度 0.70
• Cytosine Deaminase-Assisted Mutator for Genome Evolution in Cupriavidus necator
  crossref Haojie Pan, Zhijiao Wang, Jiazhang Lian 2024-06-19T01:18:02Z 置信度 0.70
• A genetic safeguard for eliminating target genes in synthetic probiotics in response to a loss of the permissive signal in a gut environment
  SUMMARY Following the development of therapeutic probiotics, there is an emerging demand for constraining engineered microbial activities to ensure biosafety. Many biocontainment studies developed genetic devices that involve cell death and growth inhibition o…
  crossref Nhu Nguyen, Miaomiao Wang, Lin Li, Clement T. Y. Chan 2024-12-27T01:36:35Z 置信度 0.70
• Robots and the Precocious Birth of Synthetic Biology
  crossref Julyan Cartwright 2024-01-16T19:59:13Z 置信度 0.70
• OptoLacI: optogenetically engineered lactose operon repressor LacI responsive to light instead of IPTG
  Abstract Optogenetics’ advancement has made light induction attractive for controlling biological processes due to its advantages of fine-tunability, reversibility, and low toxicity. The lactose operon induction system, commonly used in Escherichia coli, relie…
  crossref Meizi Liu, Zuhui Li, Jianfeng Huang, Junjun Yan 等 2024-06-11T21:36:29Z 置信度 0.70
• The Evolution of Diabetes Treatments: From Insulin Therapy to Synthetic Biology
  crossref Shubhangi Sharma, Jaspreet Kaur 2025-01-08T04:39:17Z 置信度 0.70
• An Expanded Substrate Scope for Cross-Chiral Ligation Enables Efficient Synthesis of Long L-RNAs
  ABSTRACT Despite the growing interest in mirror-image L-oligonucleotides, both as a robust nucleic acid analogue and as an artificial genetic polymer, their broader adoption in research and medicine remains hindered by challenges associated with the synthesis …
  crossref Xuan Han, Jonathan T. Sczepanski 2024-10-04T21:10:28Z 置信度 0.70
• Allele Sails: launching traits and fates into wild populations with DNA sequence modifiers
  Population-scale genome editing can be used to alter the composition or fate of wild populations. One approach to achieving these aims utilizes a synthetic gene drive element-a multi-gene cassette-to bring about an increase in the frequency of an existing alle…
  crossref Michelle L Johnson, Bruce Hay, Maciej Maselko 2024-03-20T00:45:21Z 置信度 0.70
• TCR-TRANSLATE: Conditional Generation of Real Antigen Specific T-cell Receptor Sequences
  The paradoxical nature of T-cell receptor (TCR) specificity, which requires both precise recognition and adequate coverage of antigenic peptide-MHCs (pMHCs), poses a fundamental challenge in immunology. Efforts at modeling this complex many-to-many mapping hav…
  crossref Dhuvarakesh Karthikeyan, Colin Raffel, Benjamin Vincent, Alexander Rubinsteyn 2024-11-12T22:50:12Z 置信度 0.70
• Design and synthesis of DNA origami nanostructures to control TNF receptor activation
  Abstract Clustering of type II tumour necrosis factor (TNF) receptors (TNFRs) is essential for their activation, yet currently available drugs fail to activate signalling. Some strategies aim to cluster TNFR by using multivalent streptavidin or scaffolds based…
  crossref Göktuğ Aba, Ferenc A. Scheeren, Thomas H. Sharp 2024-04-28T01:40:17Z 置信度 0.70
• Noise Reduction in Resource-Coupled Multi-Module Gene Circuits through Antithetic Feedback Control
  Abstract Gene circuits within the same host cell often experience coupling, stemming from the competition for limited resources during transcriptional and translational processes. This resource competition introduces an additional layer of noise to gene expres…
  crossref Suchana Chakravarty, Rong Zhang, Xiao-Jun Tian 2024-05-25T00:50:17Z 置信度 0.70
• Deciphering regulatory architectures from synthetic single-cell expression patterns
  Abstract For the vast majority of genes in sequenced genomes, there is limited understanding of how they are regulated. Without such knowledge, it is not possible to perform a quantitative theory-experiment dialogue on how such genes give rise to physiological…
  crossref Rosalind Wenshan Pan, Tom Röschinger, Kian Faizi, Hernan Garcia 等 2024-01-29T04:30:18Z 置信度 0.70
• A Genetically Encoded System to Quantify and Evolve RuBisCO-Catalyzed Carbon Fixation
  Abstract Strategies to study and alter the biochemical properties of RuBisCO often couple CO 2 fixation to bacterial growth. However, these viability-coupled strategies are not quantitative and are limited by toxicity of the RuBisCO substrate RuBP, the slow ki…
  crossref David L. Lanster, Zhiyi Li, Ahmed H. Badran 2024-05-16T00:05:11Z 置信度 0.70
• Synthetic Biology in T-cell Engineering Research
  Synthetic biology has emerged as a transformative discipline, enabling precise genetic and functional reprogramming of cellular systems. In T-cell engineering, it offers groundbreaking potential to revolutionize immunotherapy by endowing T cells with enhanced …
  crossref Irmak Yılmazer 2024-11-08T21:04:07Z 置信度 0.70
• Natural selection of synthetic gene drives for population suppression can favour an intermediate strength of drive
  Abstract Synthetic gene drives are being investigated as tools to suppress pest populations, and it is important to understand how natural selection will act on variant drivers that may either arise by de novo mutation or are intentionally released. In this st…
  crossref PJ Beaghton, Austin Burt 2024-11-04T03:35:14Z 置信度 0.70
• AN INSIGHT INTO SYNTHETIC AND PHARMACOLOGICAL PROFILE OF SULPHANILAMIDE
  crossref 2024-05-31T11:43:32Z 置信度 0.70
• Multicellular Proportional-Integral-Derivative Control for Robust Regulation of Biological Processes
  Abstract This paper presents the first implementation of a Proportional-Integral-Derivative (PID) biomolecular controller within a consortium of different cell populations, aimed at robust regulation of biological processes. By leveraging the modularity and co…
  crossref Vittoria Martinelli, Davide Fiore, Davide Salzano, Mario di Bernardo 2024-10-25T19:55:12Z 置信度 0.70
• ENHANCING POTENTIALITY OF FLAVONOIDS BY PREPARING SEMI SYNTHETIC DERIVATIVES
  crossref 2024-05-31T11:43:32Z 置信度 0.70
• Colorimetric CRISPR Biosensor: A Case Study with Salmonella Typhi
  There is a critical need to implement a sensitive and specific point-of-care (POC) biosensor that addresses the instrument limitations and manufacturing challenges faced in resource-constrained contexts. In this paper we focus on enteric fever which is a highl…
  crossref Ana Pascual-Garrigos, Beatriz Lozano-Torres, Akashaditya Das, Jennifer C Molloy 2024-08-06T01:41:48Z 置信度 0.70
• Modelling dynamic host-pathway interactions at the genome scale with machine learning
  Abstract Pathway engineering offers a promising avenue for sustainable chemical production. The design of efficient production systems requires understanding complex host-pathway interactions that shape the metabolic phenotype. While genome-scale metabolic mod…
  crossref Charlotte Merzbacher, Oisin Mac Aodha, Diego A. Oyarzún 2024-04-10T00:55:22Z 置信度 0.70
• Biosafety in Synthetic Biology
  Abstract The 1992 Convention on Biological Diversity defines ‘synthetic biology’ as ‘further development and a new dimension of biotechnology that combines science, technology and engineering to design, redesign, manufacture/construct and or modify genetic mat…
  crossref Sophy K. J. 2024-07-18T16:13:05Z 置信度 0.70
• Harnessing Synthetic Biology to Sense and Guide Cell-State Transitions
  crossref Lei Wang 2024-12-09T10:50:28Z 置信度 0.70