-
crossref
2017-07-15T19:26:24Z
置信度 0.70
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crossref
2025-01-18T22:23:58Z
置信度 0.70
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crossref
Salvatore Iannace, Andrea Sorrentino
2015-10-07T21:34:37Z
置信度 0.70
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2025-11-06T15:04:18Z
置信度 0.70
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crossref
2017-07-15T19:27:19Z
置信度 0.70
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crossref
2017-07-15T19:27:56Z
置信度 0.70
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crossref
2014-10-08T22:34:28Z
置信度 0.70
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crossref
2011-08-25T21:28:24Z
置信度 0.70
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crossref
Palak Singh, Devendra Singh, Hariom Sharma
2025-11-06T15:04:18Z
置信度 0.70
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crossref
Fernando Pacheco-Torgal
2025-02-28T20:36:41Z
置信度 0.70
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crossref
Chaiyan Chaiya, Sasiradee Jantasee
2022-04-01T21:50:33Z
置信度 0.70
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crossref
Liming Zhao
2025-11-17T12:02:55Z
置信度 0.70
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crossref
R. Naresh, R. Parameshwaran, V. Vinayaka Ram
2020-03-20T21:33:23Z
置信度 0.70
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crossref
2015-10-07T21:34:37Z
置信度 0.70
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crossref
R.G. Abaszade, E.A. Khanmamadova, Naveen Mani Tripathi
2025-11-06T15:04:18Z
置信度 0.70
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europepmc
2024
置信度 0.80
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europepmc
2025
置信度 0.80
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2024
置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
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置信度 0.80
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置信度 0.80
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置信度 0.80
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2026
置信度 0.80
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europepmc
2025
置信度 0.80
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europepmc
2026
置信度 0.80
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europepmc
2026
置信度 0.80
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2025
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置信度 0.80
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置信度 0.80
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置信度 0.80
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置信度 0.80
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置信度 0.80
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2025
置信度 0.80
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2024
置信度 0.80
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europepmc
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置信度 0.80
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europepmc
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置信度 0.80
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europepmc
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置信度 0.80
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置信度 0.80
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europepmc
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置信度 0.80
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europepmc
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置信度 0.80
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置信度 0.80
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置信度 0.80
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置信度 0.80
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europepmc
2024
置信度 0.80
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europepmc
2024
置信度 0.80
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置信度 0.80
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置信度 0.80
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europepmc
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置信度 0.80
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2024
置信度 0.80
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europepmc
2024
置信度 0.80
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置信度 0.80
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The high glycemic environment of diabetic wounds predisposes to bacterial infections that seriously threaten the wound healing process. Therefore, inhibition of bacterial infection and remodeling of the wound microenvironment are crucial for the healing of dia…
pubmed
Yao C, Zhang D, Kan J, Shao W 等
2026 Aug 6
置信度 0.82
-
This study pioneers the investigation of the fundamental mechanisms by which bamboo biochar (BBC) enhances volatile fatty acids (VFAs) production from cornstalk through anaerobic fermentation by rumen microorganism (RM). The results demonstrate that BBC prepar…
pubmed
Chen L, Lin J, Li N, Zhang Y 等
2026 Aug 6
置信度 0.82
-
Despite several advances in biosensor technology, reliable quantification in complex matrices remains challenging due to limitations in signal amplification, selectivity, and operational stability. The development of nanotechnology has played an important role…
pubmed
Mansouri S, Alharbi Y, Alqahtani A
2026 Aug 6
置信度 0.82
-
Phosphoketolases can convert nonphosphorylated sugars to the high-energy compound acetyl phosphate and the versatile metabolic precursor acetyl-CoA. However, their application is limited by low catalytic activity toward these substrates. Here, we report the ra…
pubmed
Kraußer F, Topham CM, Rabe K, Kundoch JO 等
2026 Aug 6
置信度 0.82
-
Hydrogenosomes are mitochondrion-derived organelles that produce ATP and H 2 to support energy metabolism in anaerobic eukaryotes. H 2 production allows reoxidation of reduced cofactors generated during fermentative metabolism; however, the metabolic mechanism…
pubmed
Zhang B, Hrdy I, Tachezy J, Gao Y 等
2026 Aug 6
置信度 0.82
-
Aminoacyl-tRNA synthetases (aaRSs) catalyze the attachment of amino acids (AAs) to their cognate tRNAs during protein synthesis. As aaRSs possess highly selective amino acid-binding sites, a distinct enzyme is generally required for each amino acid in the gene…
pubmed
Jakka SR, Jaiswal S, Reddy KM, Agarwal R 等
2026 Aug 6
置信度 0.82
-
Peptides have emerged as key regulators of cardiovascular physiology and increasingly important tools in the diagnosis and management of cardiovascular disease (CVD). Endogenous peptide systems, including natriuretic peptides (NPs), the renin angiotensin syste…
pubmed
Pabón Romero AF, Martínez C
2026 Jul-Aug
置信度 0.82
-
Type 2 diabetes mellitus (T2DM) affects over 415 million individuals globally, with excessive hepatic glucose production representing a primary contributor to hyperglycaemia. Fructose-1,6-bisphosphatase (FBP1), a rate-limiting gluconeogenic enzyme, has emerged…
pubmed
Joshi P, Mazumder A, Pentela B, Debnath A
2026 Aug 6
置信度 0.82
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Central nervous system (CNS) disorders-including ischemic stroke, traumatic brain/spinal cord injury, Parkinson's disease, and Alzheimer's disease-have long faced limitations in achieving functional recovery and disease-modifying therapies because of their com…
pubmed
Niu S, Liu X, Xu R, Zhu A 等
2026
置信度 0.82
-
Carboxylic acids are common functional handles in peptides and drug molecules, but their direct use for DBM derivatization remains limited. Herein, a bromide-mediated electrochemical α-acyloxylation of dibenzoylmethane (DBM) with amino acid-, peptide-, a…
pubmed
Jiang S, Hu F, Huang J, Zhang L 等
2026 Aug 5
置信度 0.82
-
Hawthorn ( Crataegus spp.) fruits are recognized as rich sources of phenolic compounds with well-documented antioxidant and carbohydrate-hydrolyzing enzyme inhibitory properties. However, the potential biological relevance of these phytochemicals depends large…
pubmed
Erol KF, Kutlu G, Bekiroglu H, Sagdıc O 等
2026 Aug
置信度 0.82
-
Natural product biosynthetic cytochrome P450s (CYPs) are of increasing interest for their incredible ability to selectively activate inert C-H bonds on highly complex substrates. However, these enzymes are understudied due to difficulties accessing substrates.…
pubmed
Peate J, Ding Y, Tomkins J, Winter HR 等
2026 Aug 5
置信度 0.82
-
Atrazine, widely applied in maize fields, exhibits strong stability and mobility, leading to soil ecosystem degradation, groundwater pollution, and severe phytotoxicity to succeeding common bean crops in maize-bean rotation systems. Most previously reported at…
pubmed
Cui J, Li H, Gao H, Yu T 等
2026
置信度 0.82
-
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal degeneration, oxidative stress, neuroinflammation, and gut microbiota dysbiosis. Increasing evidence highlights the role of the gut-brain axis (GBA) and…
pubmed
Ravi A, Umapathy S, Pan I
2026
置信度 0.82
-
Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder with an elusive pathophysiology. Although immune dysregulation and mild mucosal inflammation are recognized as important factors in IBS, the specific contribution of immunosenes…
pubmed
Yao Y, Li J, Zhang B, Li T 等
2026
置信度 0.82
-
(R)-3-Aminobutanol is a valuable chiral amino alcohol widely used in the pharmaceutical industry. The amine dehydrogenase (AmDH)-catalyzed synthesis with inorganic ammonia as the amine donor represents one of the most promising routes for its production. Howev…
pubmed
Huang TK, Huang C, Wu D, Li S 等
2026 Aug 5
置信度 0.82
-
The ladybird Harmonia axyridis is an important predatory natural enemy, and during both predation and oviposition it encounters interference from the black garden ant Lasius niger, as ants aggressively defend aphid colonies and thereby restrict ladybirds' acce…
pubmed
Duan Y, Li X, Zhang S, Jiao X 等
2026 Aug 5
置信度 0.82
-
Plasticizers added to plastics are toxic, endocrine-disrupting chemicals that may leach into the environment. Chemical and microbial degradation were reported to degrade the plasticizers. Most chemical methods operate at high temperature and pressure (energy-i…
pubmed
Mandal R, Sar S, Maiti T, Hazra B 等
2026 Aug
置信度 0.82
-
Lytic polysaccharide monooxygenases (LPMOs) offer a promising route to enhance the conversion of agricultural waste. Here, we characterized an Auxiliary Activities (AA) 15 family LPMO, CsAA15, derived from Cryptotermes secundus. We examined its binding affinit…
pubmed
Ma L, Liu J, Gao Y, Ji X 等
2026 Aug 5
置信度 0.82
-
Efficient lignocellulose conversion requires xylan-degrading enzymes that function without energy-intensive pretreatment. Although many xylanases have been reported, the biochemical diversity of Basidiomycota-derived enzymes remains unclear. Here, we purified …
pubmed
Okamoto K, Yasutake T, Hosoo D, Mizuta T 等
2026 Aug 5
置信度 0.82
-
Therapeutic protein overexpression can overwhelm endoplasmic reticulum (ER) folding capacity, trigger unfolded protein response (UPR) signaling, and compromise the safety of gene and mRNA therapies. Here, we engineer stress-responsive RNA rheostats that couple…
pubmed
Ogurlu R, Sanchez EB, Hull JA, Fergione SM 等
2026 Aug 5
置信度 0.82
-
Root-knot nematodes (RKNs) pose a severe threat to global agricultural production, highlighting the urgent need for effective biocontrol agents. However, the mechanisms by which biocontrol agents suppress RKNs in complex soil environments remain poorly underst…
pubmed
Dai W, Yang F, Chen W, Liu C 等
2026 Aug 4
置信度 0.82
-
Mycotoxin contamination in food systems, particularly in edible oils derived from mouldy oilseeds, remains a persistent safety challenge due to the hydrophobic and viscous nature of oils. Conventional detoxification approaches often suffer from limited selecti…
pubmed
Jahangir S, Noureen M, Geng Y, He Y 等
2026 Aug 3
置信度 0.82
-
The aging of microplastics (MPs) inevitably occurs during sludge treatment, leading to the leaching of dissolved organic matter (DOM) and associated chemical additives. However, the impact and mechanism of aged leachate on anaerobic fermentation of waste activ…
pubmed
Wu J, Hao J, Xue Y, Wu H 等
2026 Aug 3
置信度 0.82
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Polymer membranes with ionic domains represent a promising platform for biocatalytic systems, yet their super-acidity often restricts direct enzyme binding. In this study, the potential of commercial and laboratory-prepared Nafion membranes (Nafion1 and Nafion…
pubmed
Akbulut K, Balcı Ş, Usul SK, Kerimak-Öner MN 等
2026 Jul 30
置信度 0.82
-
Rapid and cost-effective detection of dengue infection, especially during the early stages of disease and in resource-limited settings, remains a significant public health concern. Recent advances in nanomaterial-based biosensors have provided promising opport…
pubmed
Seraj S, Rahaie M
2026 Aug 4
置信度 0.82
-
Leucyl-tRNA synthetase 1 (LARS1) is a multi-domain enzyme essential for translational fidelity and amino acid sensing, with its anticodon-binding domain (ABD) playing a critical role in tRNA recognition. Missense variants in LARS1 have been associated with inf…
pubmed
Tunca Alparslan G, Satkin NB, Kamer İ, Tekin İM
2026 Aug 5
置信度 0.82
-
Cancer progression involves systemic immune suppression and tumor recurrence facilitated by increased splenic protumoral myelopoiesis. To address this clinical challenge, we developed an engineered Trojan Mycobacterium as a trained immunity (TI)-mediated splen…
pubmed
Choi JH, Lee SN, Heo JH, Park S 等
2026 Aug 5
置信度 0.82
-
Alzheimer's disease (AD) remains a formidable global health challenge, driving the urgent need for potent and selective therapeutics targeting β-site amyloid precursor protein cleaving enzyme 1 (BACE1), a key enzyme involved in the generation of amyloid-…
pubmed
Kaur G, Goyal B
2026 Aug 5
置信度 0.82
-
Transaminases (TAs) represent a class of enzymes that enable highly stereoselective amination reactions under mild conditions, providing an exceptionally powerful and versatile green chemistry tool for the synthesis of chiral amines and nitrogen-containing com…
pubmed
Li YX, Lin C, Guan ZY, Zhang YS 等
2026 Aug 5
置信度 0.82
-
The increasing interest in biofuels has highlighted the potential of cyanobacteria due to their photoautotrophic mode of energy production, lower nutrient requirements for growth, and amenability to genetic modification using various genome engineering tools f…
pubmed
Kamalesan A, Kumar KK, Nathan B, Perumal R 等
2026 Aug 5
置信度 0.82
-
The development of high-performance immobilized enzymes is critical for advancing industrial biocatalysis in the food and agricultural fields. In this work, Candida rugosa lipase (CRL) was precisely immobilized on magnetic chitosan carriers functionalized with…
pubmed
Zhang W, Li Z, Li F, Wang J 等
2026 Aug 5
置信度 0.82
-
Transketolase (TKL; EC 2.2.1.1) has been validated as a potential new herbicide target. To develop a new and highly effective herbicides-targeted TKL, a series of indole-containing fusarium acid (FA) derivatives 9a-9s were designed and synthesized. Among them,…
pubmed
Li C, Liu Y, Ma X, Du Z 等
2026 Aug 5
置信度 0.82
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Due to their distinct characteristics compared to other proteases, Keratinases present a promising alternative for various industrial applications. This study focused on isolating and screening keratinolytic bacteria from poultry waste-contaminated soil, optim…
pubmed
Salimi F, Jorjani E, Salehi M, Borhani MS 等
2026 Aug 5
置信度 0.82
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Current artificial cells often lack robustness in the face of the complex physiological milieu. Additionally, the strategies for mimicking natural cargo exchange mostly rely on biological techniques, which involve integrating native channel proteins or adoptin…
pubmed
Pan Z, Zhao M, Wang Z, Li Z 等
2026 Aug 5
置信度 0.82
-
Chikungunya virus (CHIKV) infection might cause chronic chikungunya arthritis resembling rheumatoid arthritis (RA). The purpose of this study is to investigate the potential role of this virus in the pathogenesis of RA in Taiwan, a non-endemic area.
pubmed
Yen CY, Lin CC, Lin PC, Tsai CY 等
2026 Aug
置信度 0.82
-
Elevated postprandial blood glucose is a key contributor to metabolic disorders, including type 2 diabetes. Although dietary fiber is known to modulate glucose absorption and improve glycemic response, its intake remains below recommended levels in many popula…
pubmed
Nguyen TQN, Dong THT, Tran LTN, Nguyen HD 等
2026 Aug 4
置信度 0.82