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• Dietitian-led individualized pancreatic enzyme replacement therapy is associated with favorable nutritional and immune-inflammatory profiles in pancreatic cancer: a retrospective cohort study.
  Pancreatic cancer is a highly malignant tumor with extremely poor prognosis. Pancreatic exocrine insufficiency (PEI), malnutrition, and immune-inflammatory dysfunction are highly prevalent and closely interact to impair postoperative recovery and clinical outc…
  pubmed Chen X, Chen J, Zhu T, Xia B 等 2026 置信度 0.82
• Soil enzyme dynamics under PFAS contamination in arid and Mediterranean soils.
  Per- and polyfluoroalkyl substances (PFAS) are persistent contaminants increasingly detected in agricultural soils, yet their effects on extracellular enzyme activities remain poorly resolved. This study examined the short- and long-term effects of perfluorooc…
  pubmed Sanchez-Hernandez JC, Navarro Pacheco NI, Andrade Cares X, Semerád J 等 2026 置信度 0.82
• Influence of Aqueous, Ethanolic, and Hydroethanolic Extraction on Phytochemical Content and Cardiometabolic-Related Bioactivities of Four Cameroonian Spices.
  Cameroonian spices are rich in bioactive phenolics with potential applications in functional foods and nutraceuticals. Yet, the influence of solvent polarity on phytochemical extraction and the resulting multifunctional in vitro activities remains insufficient…
  pubmed Nkaleu Ngonganga KL, Nouga Bissoue A, Omgba Etoundi BC, Fogang Mba AR 等 2026 置信度 0.82
• A comprehensive review on therapeutics and diagnostic agents targeting acetyl and butyryl cholinesterases for AD.
  Alzheimer's disease (AD) is a progressive, irreversible, and multifaceted neurodegenerative disorder characterized by cognitive decline, memory loss, and behavioral impairment, posing a major global health challenge. Its multifactorial pathology includes choli…
  pubmed Chaurasia V, Das Modak S, Singh GK, Modi G 2026 置信度 0.82
• Rice straw returning to the field on soil microbial interactions, soil fertility improvement, and carbon sequestration for CO(2) emission reduction.
  Rice straw is rich in organic matter and essential nutrients, an important resource for improving soil fertility and enzyme activity. However, its high carbon-nitrogen ratio leads to slow decomposition, affecting nutrient transformation efficiency. The small m…
  pubmed Liu T, Li J, Guo H, Li L 等 2026 Aug 4 置信度 0.82
• Advanced oxidation pretreatment for lignocellulosic bioconversion: reactive species chemistry, byproduct formation, and downstream impacts.
  Lignocellulosic biomass is an abundant renewable organic carbon resource, but its compact cell-wall structure and lignin shielding limit bioconversion efficiency. Advanced oxidation processes (AOPs) have emerged as promising pretreatment approaches; however, t…
  pubmed Wang S, Wang P, Wu B, Cui M 等 2026 Aug 4 置信度 0.82
• Facilely fabricating fluorescent iron-doped polymer dots nanozyme with oxidase-like activity for dual-mode analysis of glutathione S-transferase and its inhibitor.
  Glutathione S-transferase (GST) is a key enzyme involved in detoxification, antioxidation, and signal transduction, and its abnormal activity is closely associated with tumor drug resistance, liver damage, and inflammatory diseases. In this study, a bifunction…
  pubmed Wang L, Liu W, Qiu D, Zhang G 等 2026 Aug 1 置信度 0.82
• Higenamine exerts an antidepressant effect by reducing neuronal damage induced by glutamate excitotoxicity: Based on crosstalk between astrocytes and neuron.
  Depression is one of the psychiatric disorders with the highest global disability rate. Dysfunction of the glutamatergic system is recognized as a core feature of stress-related psychiatric disorders. Previous studies have demonstrated that Higenamine (Hig) si…
  pubmed Wang H, Chen C, Tian Z, Yan Z 等 2026 Jul 21 置信度 0.82
• Engineering Ru-Fe dual-atom catalysts for multi-enzyme ROS amplification and NIR-II photothermal therapy.
  Nanocatalytic therapies using reactive oxygen species have shown promise for treating cancer; however, the efficacy of these therapies is often limited due to poor ROS generation, limited availability of endogenous hydrogen peroxide, and rapid replenishment of…
  pubmed Vazira J, Babamuratov B, Abduraximova L, Sapaev IB 等 2026 Aug 1 置信度 0.82
• Dynamic Expression of α-1,2-Glucan Synthase in Nostoc sp. PCC 7120 and Biochemical Characterization of an α-1,2-Glucan phosphorylase.
  α-1,2-glucans are polysaccharides characterized by their unique α-1,2-glycosidic bonds and right-handed helical structure, which suggest novel biological functions. The alr1000 protein in Nostoc sp. PCC 7120 is the key enzyme for synthesizing &#x3b…
  pubmed An Q, Farooq H, Wang A, Lou Y 等 2026 Aug 4 置信度 0.82
• Quantum mechanical investigation and environmental engineering of LinB for enhanced polyvinyl chloride degradation.
  Polyvinyl chloride (PVC) is one of the most widely used polymers on a global scale. However, its ability to withstand natural degradation presents substantial environmental concerns. It is imperative to identify biological solutions for PVC degradation. Conseq…
  pubmed Alam A, Agrawal GP, Foudah AI, Ahmad A 等 2026 Aug 4 置信度 0.82
• Sexually dimorphic expression and hormonal responsiveness of steroidogenic Cyp genes during gonadal differentiation in mandarin fish.
  Steroid hormones play a pivotal role in fish sex differentiation, yet the dynamic expression patterns of key steroidogenic enzymes during this process remain incompletely characterized. Here, we combined genome-wide identification, time series transcriptomes s…
  pubmed Zhang J, Lin S, Deng Z, Chen W 等 2026 Aug 4 置信度 0.82
• Research progress on the extraction and purification of plant polysaccharides: a review.
  Plant polysaccharides have attracted considerable interest in natural product research due to their immunomodulatory, antitumor, and hypoglycemic activities. The development of efficient and gentle extraction and purification techniques is crucial for obtainin…
  pubmed Qi R, Ding B, Fang M, Xiao S 等 2026 Aug 4 置信度 0.82
• Cas-regulation-targeting chimera enables selective and tunable control of CRISPR/Cas12a.
  Selective and tunable regulation of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas12a activity enables on-demand control, yet current strategies remain hindered by nonspecific regulation and limited tunability. Inspired by proximity eff…
  pubmed Li Y, Han P, Yuan R, Bai L 等 2026 Jul 17 置信度 0.82
• Nanotechnology-driven optogenetics for therapeutic grade interventions.
  Optogenetics, a biotechnology that combines optical and genetic strategies to regulate cellular and tissue functions with high spatial and temporal precision, serves as a powerful tool-level regulatory technology widely employed to investigate cellular process…
  pubmed Chen X, Zhang X, Zhao Y 2026 Aug 4 置信度 0.82
• Genome-wide characterization of the CIPK gene family in mung bean and functional validation of VrCIPK5 in drought stress response.
  Calcineurin B-like protein-interacting protein kinases (CIPKs) act as core regulators in plant calcium (Ca 2+ ) signaling pathways and mediate abiotic stress adaptation. Mung bean ( Vigna radiata L.) is an economically important legume that is widely grown in …
  pubmed Yin L, Liao J, Gao J, Xiao Y 等 2026 置信度 0.82
• Biocatalytic reduction of nitro-sulfonamides: enzyme engineering, process integration, and sustainable pathways to p-aminobenzenesulfonamide.
  Sulfonamides remain important to medicinal and fine-chemical production but conventional aniline precursor routes like Pd-catalysed hydrogenation and Béchamp reductions carry sustainability, safety, and chemoselectivity challenges, especially for N-S bond…
  pubmed Ai R, Muhammad N, Cui Y, Wang L 等 2026 置信度 0.82
• Directed evolution of chlorotoxin enhances MMP-2 recognition and improves CAR-T-cell activity in glioblastoma models in vitro.
  Cysteine-rich miniproteins from venomous animals are promising therapeutic scaffolds due to their compact structure, high stability, and low immunogenicity. Chlorotoxin (CTX), a miniprotein derived from scorpion venom, selectively targets glioblastoma by bindi…
  pubmed Hajdara A, Szöőr Á, Murányi J, Brunyánszki A 等 2026 置信度 0.82
• The shape of fitness functions and the distribution of mutational effect sizes jointly limit adaptation by regulatory mutations.
  Mutations in gene regulatory regions have been shown to play a role in rapid adaptation, but the factors determining their contribution are largely unknown. Here, using the metabolic enzyme cytosine deaminase of budding yeast, we examine whether adaptation to …
  pubmed Aubé S, Dubé AK, Landry CR 2026 Aug 3 置信度 0.82
• Engineering strategies and translational progress in targeted nanoparticle drug delivery.
  Nanoparticle-based drug delivery has emerged as a transformative approach in modern therapeutics, offering improved targeting efficiency, enhanced pharmacokinetics, and reduced systemic toxicity compared to conventional drug delivery systems.
  pubmed Ajay N, Shibi Anilkumar A, Veerabathiran R 2026 Aug 3 置信度 0.82
• Impact of food matrix on the activity of a phage-derived thermostable modular lytic enzyme against Salmonella in dairy products.
  Food contamination remains a major challenge for the food industry, including the dairy sector. Rich and complex composition of milk provides an excellent environment for the growth of pathogenic microorganisms, among which the most common bacterial contaminan…
  pubmed Kocot AM, Rusinek W, Majkowska A, Grimon D 等 2026 Aug 3 置信度 0.82
• SRG16 alleviates cadmium-induced heavy metal stress in soybean (Glycine max (L.) Merr.).
  Cadmium (Cd) is among the most common toxic heavy metal pollutants in nature. Cd exposure causes physical damage and toxicity in many organisms. In this study, we observed root growth from soybean (Glycine max (L.) Merr.) plants that were exposed to 15 …
  pubmed Zikun Z, Yu Z, Tuerdaken R, Dawei X 等 2026 Jul 11 置信度 0.82
• Phenotypical, physiological and molecular identification in Bougainvillea × buttiana 'Miss Manila' leaves by radiation stress.
  The beautiful bract coloration of Bougainvillea × buttiana 'Miss Manila' renders it significant for both landscaping and as a key source material for betaine extraction. To understand its response to gamma rays irradiation, we exposed cuttings to varying …
  pubmed Wu K, Lin H, Wang J, Chen J 2026 Jul 30 置信度 0.82
• Identification and characterization of a novel α-L-fucosidase from Desertivirga arenae for efficient L-fucose biosynthesis in metabolically engineered Escherichia coli.
  L-Fucose is a physiologically important monosaccharide widely present in various biomass resources, especially microalgae. Metabolically engineered microbial systems have gained growing interest for L-fucose production due to their high yield and industrial sc…
  pubmed Meng J, Li A, Lu Z, Zhang W 等 2026 Aug 1 置信度 0.82
• Comprehensive research on berry polysaccharides: Extraction, structure, mechanism, structure-activity relationship and application from traditional insight to intelligent prediction.
  As natural bioactive macromolecules isolated from various berries, Berry polysaccharides (BPs) possess excellent biocompatibility, low toxicity and diverse health-promoting properties, which has garnered extensive interest in functional food and pharmaceutical…
  pubmed Wang Z, Zhang R, Ling N, Gao M 等 2026 Jul 23 置信度 0.82
• Gradient orbital coupling to boost radical adsorption on Cu atom sites for efficient biocatalytic performance.
  Molybdenum disulfide (MoS 2 ) holds broad application prospects in the biomedical field, yet its inherent enzyme-mimetic activity exhibits limitations. This study reveals that Cu doping unleashes exceptional biocatalytic activity of MoS 2 by forming d-p-d grad…
  pubmed Guo M, Wei Z, Xue X, Li L 等 2026 Jul 31 置信度 0.82
• Reprogramming ligand-receptor interactions via a self-powered molecular engine for proton-responsive regulation of cellular motility.
  Manipulation of ligand-receptor interactions (LRIs) in a user-defined manner is one of the effective ways to regulate cell motility and disease progression. Molecular engines orchestrate LRIs to regulate cell motility by harnessing various forms of energy…
  pubmed Li Y, Wang H, Zhang G, Wang Y 等 2026 Jul 30 置信度 0.82
• ACE2-PNA conjugates exploit viral endocytosis for targeted intracellular delivery and exhibit dual antiviral efficacy against SARS-CoV-2.
  The COVID-19 pandemic and its protracted consequences underscore the urgent need for more effective antiviral strategies. Current antiviral strategies face a persistent challenge achieving sufficient viral suppression while minimizing off-target toxicity, part…
  pubmed Wang Y, Xu J, Chen Y, Xiao X 等 2026 Aug 3 置信度 0.82
• Overcoming Tumor Hypoxia and Adenosine-mediated Immunosuppression for Boosting Photodynamic Therapy and Systemic Antitumor Immune Responses.
  Photodynamic therapy (PDT)-induced immunogenic cell death (ICD) is an important approach for enhancing in situ tumor immunogenicity and activating systemic immune response. However, the tumor immunosuppressive microenvironment often limits the immunotherapeuti…
  pubmed Zhang X, Li W, Zheng C, Ding L 等 2026 Aug 3 置信度 0.82
• Genome-Wide Identification and Functional Characterization of CaGRAS43 in Enhancing Cold Stress Tolerance in Pepper.
  Cold stress severely limits plant growth and crop productivity, necessitating the identification of key regulatory genes that enhance tolerance. In this study, we performed a genome-wide identification and expression analysis of the GRAS transcription factor f…
  pubmed Yuan W, Ullah I, Mishra R, Hussain A 等 2026 Jul-Aug 置信度 0.82
• Biallelic variants in IBA57 with multiple mitochondrial dysfunction syndrome 3.
  Multiple mitochondrial dysfunction syndrome type 3 (MMDS3; OMIM #615330) is a rare autosomal recessive disorder caused by mutations in IBA57 . Its complex clinical presentation and molecular pathogenesis remain incompletely understood.
  pubmed Huang Y, Gou C, Chen Y, Pan Q 等 2026 置信度 0.82
• Hepatotoxicity in the Era of Precision Medicine: Toxicological Mechanisms and Management of Immune and Cell Therapy-Induced Liver Injury.
  Immune checkpoint inhibitors and adoptive cell therapies have revolutionized cancer treatment, yet their success is accompanied by immune-related hepatotoxicity that can range from asymptomatic enzyme elevation to life-threatening liver failure. Unlike convent…
  pubmed Fan Y, Guo X, Lyu J, Wang X 等 2026 Aug 2 置信度 0.82
• [Transcriptomics study of total flavonoids from Hemerocallis citrina in improving emotional behaviors in chronic stress mice via regulating 5-hydroxytryptamine signaling pathways].
  This study aims to investigate the improving effects and potential molecular mechanisms of total flavonoids from Hemerocallis citrina(HCFs) on depression-like behaviors induced by chronic unpredictable mild stress(CUMS) in mice. The mice were randomly divided …
  pubmed Hao M, Li HY 2026 Jun 置信度 0.82
• Fermentation-induced changes in Bupleurum: A study on flavonoids, polyphenols, antioxidant capacity, and metabolomic analysis.
  Previous studies have indicated that the process of herbal fermentation can enhance the bioactive components of the plant. Bupleurum, a traditional Chinese herb, is used to treat conditions such as colds and inflammation. This study used Bacillus velezensis PV…
  pubmed Liu C, Liu L, Chen Y, Li P 等 2026 Aug 1 置信度 0.82
• Mechanistic insights into PFHxS phytotoxicity and uptake dynamics in Lupinus polyphyllus.
  Perfluorohexane sulfonic acid (PFHxS), a recently classified persistent organic pollutant, is being increasingly detected in agricultural soils, yet its phytotoxicity, uptake and trophic transfer remain poorly understood. We investigated the effects of PFHxS o…
  pubmed Odoh CK, Hosain MT, Zhang H, Egbuatu M 等 2026 Aug 1 置信度 0.82
• Food enzyme safety: an extensive lineage of safe Aspergillus niger production strains.
  Aspergillus niger has been used for decades in the production of food enzymes and other fermented food ingredients. Ensuring the safety of microbially produced enzymes requires comprehensive safety assessments, supported by manufacturing best practices that co…
  pubmed Galano M, van den Dungen MW, Montaguti P, Welzer M 等 2026 Aug 1 置信度 0.82
• 1-MCP pretreatment combined with SO(2) preservation pad delays postharvest senescence and softening of 'Shine Muscat' grapes by regulating cell-wall metabolism and antioxidant activity.
  Quality deterioration of 'Shine Muscat' grapes involves tissue softening, aroma loss, and flavor alteration. This study investigated the effects of single and combined treatments of 1-methylcyclopropene (1-MCP) and preservation pads (SO 2 -pad) on physiologica…
  pubmed Chen C, Lan P, Nan Z, Li C 等 2026 Jul 30 置信度 0.82
• Discovery of novel indole-chalcone derivatives as potent hexokinase 2 inhibitors for triple negative breast cancer therapy.
  Accelerated glucose metabolism is one of the important characteristics of cancer cells. Hexokinase 2 (HK2) is the rate-limiting enzyme that catalyzes the first step reaction of the glycolytic pathway and it is always found overexpressed in various tumor cells.…
  pubmed Liu D, Cheng G, Wei Y, Xiong X 等 2026 Jul 30 置信度 0.82
• A 3-step static mechanistic modeling approach to predicting transporter- and enzyme-mediated interaction signals of direct oral anticoagulants.
  Direct oral anticoagulants (DOACs) are susceptible to drug-drug interactions involving both transport and metabolism. The relative contribution of intestinal transporters in DOAC pharmacokinetics, however, is uncharacterized, hindering the prediction of their …
  pubmed Ben Ahmed M, Filppula AM, Tornio A 2026 Jul 6 置信度 0.82
• Design of a red-emitting camphor-derived benzothiazole ratiometric fluorescent probe for hydrazine detection in environmental samples and its versatile imaging applications in live cells, zebrafish and Arabidopsis thaliana.
  Hydrazine (N 2 H 4 ) has been extensively utilized during industrial production, while its excessive usage presents substantial risks to human health and ecological systems. In this paper, a new red-emitting camphor-derived benzothiazole-based ratiometric fluo…
  pubmed Wang M, Gu Y, Zhao M, Zhang S 等 2026 Jul 24 置信度 0.82
• Hyaluronidase-Responsive MSN-HA Coatings for Infection-Triggered Antibiotic Delivery on Titanium Surfaces.
  Implant-associated infections remain a major challenge due to biofilm formation and uncontrolled antibiotic release from conventional coatings. This study presents an enzyme-responsive nanoparticle-based coating designed to enable localized and on-demand antib…
  pubmed Yolum M, Önder S 2026 Aug 置信度 0.82
• Foam-Bed Bioreactor With Immobilized Aspergillus welwitschiae for Efficient Tannin Removal: Optimization and Performance Evaluation.
  Tannins are polyphenolic compounds commonly found in industrial effluents posing threats to aquatic ecosystems and treatment processes due to their resistance to biodegradation. Efficient and eco-friendly removal methods are urgently needed to mitigate their e…
  pubmed Makba F, Sayed K, Patil RC, Wan-Mohtar WHM 等 2026 Aug 置信度 0.82
• Upgrading sesame cake-extracted oil via enzymatic glycerolysis: Production and characterization of diacylglycerol-enriched oil.
  Solvent-extracted oil from pressed sesame cake has limited value due to flavor loss. This study developed an enzymatic strategy to convert it into diacylglycerol (DAG)-enriched oil via Novozym 435-catalyzed glycerolysis. Under optimized conditions (molar ratio…
  pubmed Zhou L, Mu Y, Zhang J, Zheng M 等 2026 Aug 置信度 0.82
• Immobilization of glucose oxidase and catalase on magnetite nanoparticles as functional catalyst supports.
  In this work, we have prepared magnetite nanoparticles (MNPs) coated with polyethylenimine (PEI) to obtain a positively charged surface and showed their suitability as functional supports to successfully immobilize glucose oxidase (GOx) and catalase (CAT) enzy…
  pubmed Valls-Chiva A, Hornos F, Hueso JL, Martín-Pardillos A 等 2026 Jul 14 置信度 0.82
• Vibrio parahaemolyticus (AHPND) infection altered eicosanoid biosynthesis in the gastrointestinal tract of Litopenaeus vannamei.
  Acute Hepatopancreatic Necrosis Disease (AHPND) is one of the main culprits for massive shrimp mortality in the aquaculture industry. AHPND is caused by Vibrio parahaemolyticus (VP AHPND ) containing plasmids for the PirA and PirB binary toxins. These toxins c…
  pubmed Wimuttisuk W, Yotbuntueng P, Deenarn P, Tobwor P 等 2026 Sep 置信度 0.82
• Evaluating Alkaline Phosphatase-Instructed Self-Assembly of d‑Peptide Diesters for Selectively Inhibiting Immunosuppressive Cancer Cells.
  Hypoxia-driven adenosinergic signaling suppresses antitumor immunity and enables many tumors to evade cancer immunotherapy. Alkaline phosphatase (ALP) contributes to this immunosuppression by hydrolyzing extracellular adenosine triphosphate (ATP) to adenosine.…
  pubmed Yi M, Ashton-Rickardt G, Qiao Y, Huang Y 等 2026 Jul 28 置信度 0.82
• Bacteriophage lysins: a promising strategy for combating foodborne pathogens in food safety.
  Food safety is a major public concern, with foodborne pathogens such as Staphylococcus aureus , Listeria monocytogenes , Clostridium perfringens , and Vibrio parahaemolyticus causing millions of infections and significant economic losses annually. Phage and en…
  pubmed Wei J, Zhang Y, Li Y, Wang L 2026 置信度 0.82
• Favorable safety and immunogenicity of a combined quadrivalent influenza and recombinant SARS-CoV-2 vaccine in Sprague-Dawley rats for both primary and booster immunization.
  The concurrent circulation of influenza viruses and SARS‑CoV‑2 continues to strain global public health systems. Vaccination remains the cornerstone of defense, and combined vaccines offer a strategic advantage by simplifying logistics, reducing …
  pubmed Shao J, Zhang C, She G, Qin T 等 2026 置信度 0.82
• Synergistic Toxicity of PVC Microplastic and Methyl Thiophanate in Common Carp.
  Little is known about how microplastics (MPs) interact with other environmental pollutants. In light of this, the present work investigated the individual and combined toxicity of polyvinyl chloride (PVC) MPs and the fungicide methyl thiophanate (MT) in common…
  pubmed Kharkan J, Sayadi MH 2026 Jul 31 置信度 0.82
• Metal-organic framework nanozymes for dual-mode sensing of heavy metal ions: design strategies, mechanisms, and applications.
  Heavy metal pollution poses severe threats to environmental safety and human health, driving the demand for highly sensitive and selective detection technologies. Metal-organic framework (MOF)-based nanozymes have emerged as promising sensing platforms due to …
  pubmed Ge X, Liu D, Lin H, Zhao D 等 2026 Aug 1 置信度 0.82
• Foliar serotonin and allantoin mitigate tellurium toxicity in Quinoa (Chenopodium quinoa Willd.) through antioxidant activation and nutrient homeostasis to enhance yield and grain quality.
  Tellurium toxicity severely impairs soil health, plant physiology and crop productivity, posing a critical threat to global food security, ecosystem sustainability and human health. The exogenous application of phytohormones and osmoprotectants offers a sustai…
  pubmed Iqbal R, Mehmood H, Hyder S, Jabborova D 等 2026 Dec 31 置信度 0.82
• Efficient production of a self-amplifying RNA vaccine sequence with the single subunit RNA polymerase from Klebsiella phage 32 utilising the native AU initiating dinucleotide.
  RNA polymerase (RNAP) is the enzyme that produces RNA for an increasingly large variety of uses. The need for efficient industrial production of high quantities of mRNA was exemplified during the SARS-CoV-2 pandemic. While the RNAP from the T7 bacteriophage ha…
  pubmed Price MA, Trubitsyna M, Paget JE, Baker BW 等 2026 Jul 31 置信度 0.82
• Quercetin-carboxymethyl chitosan‑hydrogen nanomicelles for the treatment of chemotherapy induced oral mucositis in mice.
  Chemotherapy-induced oral mucositis (CIOM) is a debilitating adverse effect characterized by oxidative stress and inflammatory cascade-driven mucosal injury, yet current clinical interventions remain largely symptomatic and fail to address the underlying patho…
  pubmed Chen D, Uddin S, Wang B, Yao H 等 2026 Jul 31 置信度 0.82
• Heat shock transcription factor splicing variant TtHSF2β-I regulates lignocellulose and lignin-related compound degradation in Trametes trogii S0301.
  White-rot fungi are the primary biological decomposers of lignocellulosic biomass owing to their powerful lignin-modifying enzyme (LMEs) system. Here, we analyzed the regulatory role of TtHSF2β-I, an alternatively spliced variant of heat shock transcript…
  pubmed Dong Z, Zhang Y, Wu Q, Yang E 等 2026 Jul 31 置信度 0.82
• Biosynthesis of isoprene glycol from glucose by metabolically engineered Escherichia coli.
  Isoprene glycol (ISPG) is a valuable humectant used in the cosmetic industry. However, its current commercial production relies on conventional petrochemical processes, which are energy-consuming and non-sustainable. To establish a green alternative, we engine…
  pubmed Chen AY, Hung JJ, Lan EI 2026 Jul 31 置信度 0.82
• A rapid and accurate discrimination of Hedyotis diffusa Willd. from its adulterants.
  This study aimed to establish the molecular biology analytical methods based on the ladder-shaped melting temperature isothermal amplification (LMTIA) and the proofreading enzyme-mediated probe cleavage (Proofman), and two dual-LMTIA methods were developed for…
  pubmed Zhou D, Guo L, Wang Y, Cao Y 等 2026 Jul 31 置信度 0.82
• Machine learning-assisted enzyme engineering
  crossref 2020-06-12T07:48:02Z 置信度 0.70
• A beginner's guide to molecular dynamics simulations and the identification of cross-correlation networks for enzyme engineering
  crossref 2020-05-04T18:55:13Z 置信度 0.70
• Physics-based modeling in the new era of enzyme engineering.
  europepmc 2025 置信度 0.80
• Enzyme: Incremental View Maintenance for Data Engineering
  Materialized views are a core construct in database systems, used to accelerate analytical queries and optimize batch pipelines for extract-transform-load (ETL) workflows. Maintaining view consistency as underlying data evolves is a fundamental challenge, espe…
  arxiv Ritwik Yadav, Supun Abeysinghe, Min Yang, Jeffrey Helt 等 2026-03-29T17:14:56Z 置信度 0.78 cs.DB
• Multimodal Regression for Enzyme Turnover Rates Prediction
  The enzyme turnover rate is a fundamental parameter in enzyme kinetics, reflecting the catalytic efficiency of enzymes. However, enzyme turnover rates remain scarce across most organisms due to the high cost and complexity of experimental measurements. To addr…
  arxiv Bozhen Hu, Cheng Tan, Siyuan Li, Jiangbin Zheng 等 2025-09-15T11:07:26Z 置信度 0.78 cs.LGq-bio.BM
• Optimal enzyme rhythms in cells
  Cells can use periodic enzyme activities to adapt to periodic environments or existing internal rhythms and to establish metabolic cycles that schedule biochemical processes in time. A periodically changing allocation of the protein budget between reactions or…
  arxiv Wolfram Liebermeister 2016-02-16T20:27:47Z 置信度 0.78 q-bio.MN
• Structures, Functions, and Mechanisms of Filament Forming Enzymes: A Renaissance of Enzyme Filamentation
  Filament formation by non-cytoskeletal enzymes has been known for decades, yet only relatively recently has its wide-spread role in enzyme regulation and biology come to be appreciated. This comprehensive review summarizes what is known for each enzyme confirm…
  arxiv Chad K. Park, Nancy C. Horton 2019-09-28T19:40:13Z 置信度 0.78 q-bio.BM
• Assured LLM-Based Software Engineering
  In this paper we address the following question: How can we use Large Language Models (LLMs) to improve code independently of a human, while ensuring that the improved code - does not regress the properties of the original code? - improves the original in a ve…
  arxiv Nadia Alshahwan, Mark Harman, Inna Harper, Alexandru Marginean 等 2024-02-06T20:38:46Z 置信度 0.78 cs.SE
• Beyond Self-Promotion: How Software Engineering Research Is Discussed on LinkedIn
  LinkedIn is the largest professional network in the world. As such, it can serve to build bridges between practitioners, whose daily work is software engineering (SE), and researchers, who work to advance the field of software engineering. We know that such a …
  arxiv Marvin Wyrich, Justus Bogner 2024-01-04T13:38:51Z 置信度 0.78 cs.SEcs.CY
• Journal of Enzyme Engineering
  crossref 2025-02-28T15:35:34Z 置信度 0.70
• Enzyme Engineering: Old and New Approaches
  crossref 2015-05-07T09:30:39Z 置信度 0.70
• Editor Note: Enzyme engineering
  crossref Lahiru N Jayakody 2016-08-31T17:40:54Z 置信度 0.70
• Innovation in Enzyme Engineering
  crossref Lemuel B. Wingard 2013-02-21T11:42:29Z 置信度 0.70
• Achievements and Predicted Developments in Enzyme Engineering
  crossref Ephraim Katchalski-Katzir 2012-02-28T14:29:29Z 置信度 0.70
• Recent Trends of Enzyme Engineering in Japan
  crossref Hirotoshi Samejima 2012-03-30T12:40:25Z 置信度 0.70
• Developments and Challenge of Enzyme Engineering
  crossref Lemuel B. Wingard 2012-03-30T08:40:25Z 置信度 0.70
• Metagenomics: A New Opportunity for Enzyme Engineering
  crossref Zhenyang G Mohamad KM 2015-05-07T05:30:39Z 置信度 0.70
• Recent Trends in Enzyme Engineering in Japan
  crossref S. Suzuki, I. Karube, H. Samejima 2013-02-21T11:42:29Z 置信度 0.70
• Recent Developments and Future Aspects of Enzyme Engineering
  crossref E. Katchalski-Katzir 2013-02-25T13:14:39Z 置信度 0.70
• Review for "Nano-Enzyme Engineering: Advancing Enzyme Immobilization for Industrial and Environmental Applications"
  crossref 2026-05-28T21:09:04Z 置信度 0.70
• Problems of Efficiency and Optimization in Enzyme Engineering
  crossref A. Köstner, E. Siimer 2012-04-08T00:56:13Z 置信度 0.70
• Engineering aldolases for asymmetric synthesis
  crossref 2020-08-07T17:19:39Z 置信度 0.70
• Immobilized Enzyme Pipette — ‘Impette’
  crossref P. V. Sundaram 2012-02-28T09:29:29Z 置信度 0.70
• Application of Enzyme in Pharmaceutical Engineering
  crossref Ouyang Tu 2022-08-24T04:10:41Z 置信度 0.70
• Enzyme Engineering and Evolution: Specific Enzyme Applications
  crossref 2020-09-14T07:53:13Z 置信度 0.70
• Enzyme Channelling Immunoassay. A New Homogeneous Enzyme Immunoassay Technique
  crossref Edwin F. Ullman, David J. Litman 2012-02-28T14:29:29Z 置信度 0.70
• Enzyme engineering
  crossref A. Rosevear, John F. Kennedy 2008-08-23T06:35:09Z 置信度 0.70
• Enzyme Engineering by Phage Display
  crossref Patrice Soumillion, Daniel Legendre, Jacques Fastrez 2010-02-23T14:07:26Z 置信度 0.70
• Characterization of Membranes for Enzyme Retention
  crossref E. Flaschel 2012-02-28T14:29:29Z 置信度 0.70
• Scale-Up of Enzyme Purification
  crossref Henry R. Bungay 2013-02-21T06:42:29Z 置信度 0.70
• Enzyme engineering: Directed mutagenesis
  crossref Bernard Y. Tao 2003-02-04T21:26:05Z 置信度 0.70
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