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• Development and Application of Microfluidics in Synthetic Biology
  crossref Boris Kirov 2020-04-13T11:02:57Z 置信度 0.70
• Biosecurity Risks in Synthetic Biology
  crossref Leyma Pérez, De Haro 2024-08-08T18:41:23Z 置信度 0.70
• Biosafety Considerations of Synthetic Biology: Lessons Learned from Transgenic Technology
  crossref Wei W Pei L 2015-01-05T06:27:45Z 置信度 0.70
• Overview of Synthetic Biology
  crossref Khushal Khambhati, Khushbu Panchal, Vijai Singh 2026-05-18T00:42:53Z 置信度 0.70
• What Is Synthetic Biology?
  crossref Karen M. Polizzi 2013-08-30T20:48:21Z 置信度 0.70
• Synthetic Biology in Situ
  crossref Andrew S. Balmer, Katie Bulpin, Susan Molyneux-Hodgson 2016-06-04T05:10:52Z 置信度 0.70
• Standardization and Modularity in Synthetic Biology
  crossref Juveriya Israr, Ajay Kumar 2026-05-17T22:08:46Z 置信度 0.70
• Self-assembly at the multi-scale level: challenges and new avenues for inspired synthetic biology modelling
  crossref Giuseppe Milano, Irene Marzuoli, Chris D. Lorenz, Franca Fraternali 2017-12-18T10:37:25Z 置信度 0.70
• Microbial Platform Cells for Synthetic Biology
  crossref Dong-Woo Lee, Sang Jun Lee 2015-11-03T10:19:59Z 置信度 0.70
• Gene expression in synthetic biology: Going with the light.
  Inducible expression of endogenous and foreign genes has been a pivotal driving force behind a lot many seminal breakthroughs in biotechnology. Synthetic biology, a very promising field, largely relies on transgene expression platforms which facilitate conveni…
  europepmc 2026 置信度 0.80
• The Promise of Synthetic Biology for Redesigning Plant Architecture.
  Ensuring global food security under accelerating climate change requires transformative approaches to crop improvement that extend beyond the limits of traditional breeding and gene editing. While domestication and modern agriculture have delivered substantial…
  europepmc 2026 置信度 0.80
• Special Issue on Mammalian Cell Synthetic Biology.
  europepmc Karmella A. Haynes, Francesca Ceroni, Elizabeth Wayne 2026 置信度 0.80
• Synthetic biology as an empirical tool for evolutionary theory
  Evolutionary biology has traditionally inferred process from patterns in extant organisms and the fossil record, leaving many foundational questions constrained by their historical nature. Over the past two decades, synthetic and high-throughput approaches — i…
  europepmc Xueying Li, Paco Majic, Cauā Westmann 2026 置信度 0.80
• From Circuits to Symphonies: A Systems-Engineering Blueprint for Multimicrobial Synthetic Biology.
  Synthetic biology is expanding from single-species engineering toward the design of synthetic microbial consortia capable of distributed metabolism, coordinated behavior, and enhanced functional robustness. However, engineering frameworks derived from intracel…
  europepmc 2026 置信度 0.80
• Synthetic Biology for Discovery and Production of Anti-Microbial Drugs
  Microorganisms naturally produce many pharmaceutically and industrially relevant secondary metabolites. For this process they usually use biosynthetic units. For example, microbes from the genus Streptomyces possess great ability to produce a variety of natura…
  europepmc Sergii Krysenko, Meng Shi, Xolani H. Makhoba 2026 置信度 0.80
• Editorial: Biomolecule production in plant synthetic biology.
  europepmc Sichul Lee, Moonhyuk Kwon 2026 置信度 0.80
• S-layers as natural building blocks for nanobiotechnology and synthetic biology.
  Crystalline bacterial cell surface layers (S-layers) are self-assembling protein lattices that constitute the outermost envelope structure of many Bacteria and most Archaea. Beyond their classical role as cell surface components, S-layers are increasingly reco…
  pubmed Uwe B Sleytr, Bernhard Schuster, Sleytr UB, Schuster B 2026 置信度 0.82
• Silkworm synthetic biology: Toolkit development, chassis engineering, and biomanufacturing applications.
  The silkworm, Bombyx mori, is not only an economically important insect but also an increasingly promising chassis for insect synthetic biology. This potential arises from features including a well-characterized genetic background, established germline enginee…
  pubmed Wang L, Wen Y, Ran G, Long D 2026 置信度 0.82
• Protein modification: convergence of artificial intelligence, synthetic biology, and nano-assembly.
  europepmc 2026 置信度 0.80
• Microbial production of xanthohumol driven by synthetic biology approaches.
  europepmc 2026 置信度 0.80
• Imagining an ethics for synthetic biology.
  europepmc Varsha Aravind Paleri, Kristien Hens 2026 置信度 0.80
• Caffeinated Coli: Inspiring the Next Generation of Scientists through Synthetic Biology
  europepmc 2026 置信度 0.80
• Synthetic biology and genome engineering in support of human, agricultural, and environmental security.
  europepmc 2026 置信度 0.80
• Sustainable production of natural sweeteners through synthetic biology.
  europepmc 2026 置信度 0.80
• Biomimetic polymers and their characterization: toward sustainable materials using synthetic biology.
  Biomimetic polymers have emerged as a powerful class of materials that are capable of replicating biological processes, functions, properties, or structures found in natural systems. While extensive reviews are available due to the significant progress in synt…
  pubmed Ramasinghe LP, Regunton AK, Held MA, Cimatu KLA 2026 置信度 0.82
• Engineered bacteria in disease diagnosis and therapy: A synthetic biology perspective.
  Synthetic biology is an interdisciplinary field that integrates knowledge and techniques from modern biology and many other disciplines to design and construct novel biological systems or to modify existing life forms. Its core technologies include gene editin…
  pubmed Yan Shen, Si-Ming Lu, Long Yang, Yang Li 等 2026 置信度 0.82
• Discovering what is possible: How synthetic biology illuminates development.
  europepmc 2026 置信度 0.80
• Programmable regenerative tissues: Converging mammalian synthetic biology and tissue engineering.
  Synthetic biology can program cellular behavior but remains underused in regenerative medicine. This commentary argues that integrating synthetic biology with tissue engineering should target vascularization and immune integration through compact, context-awar…
  europepmc 2026 置信度 0.80
• Synthetic Mirror Bacteria as a Frontier for Chiral Synthetic Biology and Biocontainment.
  ABSTRACT Chirality is a fundamental structural property of biological molecules that governs molecular recognition, enzymatic catalysis, and genetic information processing in living systems. Natural life exhibits a universal pattern of homochirality in which p…
  pubmed Mohammad Nazrul Islam Bhuiyan, Bhuiyan MNI 2026 置信度 0.82
• Reimagining Lignin Valorization: Synthetic Biology-Enabled Sustainable Aromatic Carbon Biomanufacturing.
  ABSTRACT Lignin, the largest renewable aromatic carbon reservoir, represents a foundational yet underutilized feedstock for sustainable biomanufacturing. Despite decades of effort, its effective integration remains constrained, not only by inefficient depolyme…
  pubmed Li N, Zhangyang JJ, Li BZ, Liu ZH 等 2026 置信度 0.82
• Advancing synthetic biology with engineered chemically inducible gene regulatory systems.
  Chemically inducible gene regulatory systems, with inducible promoters as their core regulatory elements, are central to advancing synthetic biology by enabling precise, dynamic, and orthogonal control of gene expression in response to chemical signals. Recent…
  pubmed Li X, Su Y, Zhang Y, Ji C 等 2026 置信度 0.82
• Editorial: Biofabrication and synthetic biology for enhanced medicinal plant bioproduction.
  pubmed Ahmad Z, Faisal M, Martinez-Montero ME 2026 置信度 0.82
• Functional Engineering of Bioactive Peptides: Chemical Modifications and Synthetic Biology Approaches.
  Bioactive peptides (BPs) are widely distributed and exhibit remarkable physiological activities. However, their natural forms are frequently characterized by short half-lives, low membrane permeability, poor stability, and inadequate oral bioavailability, whic…
  pubmed Hu L, Zhang Z, Li X, Liang Y 等 2026 置信度 0.82
• Recent advances in decoding biosynthetic pathways and synthetic biology approaches for plant alkaloids.
  europepmc 2026 置信度 0.80
• Advances in microbial extracellular vesicles: synthetic biology platforms and medical applications.
  Extracellular vesicles (EVs), typically ranging from 20 to 400 nanometers in diameter, are membrane-bound structures released into the extracellular environment by bacteria via specific secretion mechanisms. Consequently, these vesicles play a crucial role in …
  pubmed Tang ZY, Yang XL, Zhou YW, Zou H 等 2026 置信度 0.82
• Better synthetic biology outcomes through balanced push-pull engineering.
  europepmc Blanca Jazmin Reyes-Hernández 2026 置信度 0.80
• Bacteriophage P22 Virus-Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology.
  Advancing the utility of plant synthetic biology requires the continued development of protein engineering tools. Self-assembling protein compartments, such as virus-like particles (VLPs), provide versatile scaffolds for synthetic biology. However, few plant-e…
  pubmed Harding MD, Jackson MA, Gilding EK, Craik DJ 等 2026 置信度 0.82
• How custom polymerases are driving innovation in synthetic biology.
  europepmc Mohammad Hajjar, Alex R. Horton, Victoria A. Maola, Nicholas Chim 等 2026 置信度 0.80
• Chemical organizations as a conceptual tool: from synthetic biology to interdisciplinary systems and back.
  This article presents a synthetic biology framework called Chemical Organization Theory (COT), that formalizes synthetic biology concepts using reaction networks. We show how this formalism applies across synthetic biology scales, from genetic circuits and met…
  europepmc 2026 置信度 0.80
• Synthetic biology for phytohormone production.
  europepmc Pattarawan Intasian, Ninlapan Kimprasoot, Duangthip Trisrivirat, Pimchai Chaiyen 2025-12-27T10:24:44Z 置信度 0.80
• Engineering programmable floating wetlands: synthetic biology, sensing, and AI control for water quality.
  Floating treatment wetlands (FTWs) are increasingly used as nature-based water infrastructure, but their performance is often limited by oxygen transfer, hydrodynamic variability, and unstable microbiomes. This review synthesizes bioaugmentation evidence from …
  pubmed Berhanu A, Afzal M, Xian Y, Zhan L 等 2026 置信度 0.82
• Synthetic biology for heparin biomanufacturing.
  europepmc 2026 置信度 0.80
• Synthetic Biology Approaches to Enzymology in Food and Agriculture Systems.
  europepmc 2026 置信度 0.80
• Micropeptides in Cancer and Immunity: Diagnostic, Therapeutic, and Synthetic Biology Frontiers.
  Micropeptides are emerging as a previously hidden layer of the human proteome, redefining the long-standing separation between coding and noncoding genomic regions. Once dismissed as translational noise, sORFs embedded within lncRNAs, circRNAs, pseudogenes, an…
  europepmc 2026 置信度 0.80
• Filamentous fungal synthetic biology: Current applications and ongoing developments.
  europepmc Richard A. Hill 2026 置信度 0.80
• Endogenous constitutive promoters with a broad range of transcriptional activities for plant synthetic biology.
  europepmc 2026 置信度 0.80
• The plant Golden Gate toolkit: compatibility, interoperability, and harmonized assembly in plant synthetic biology.
  In plant synthetic biology, the emergence of Golden Gate (GG) cloning has led to the rapid development of numerous cloning kits that enable the standardized assembly of genetic modules and transcriptional units through a single, one-pot reaction. However, this…
  pubmed Bélanger JG, Hanaishi S, Péret B 2026 置信度 0.82
• Leveraging the bacteria for enhanced cancer immunotherapy: from a perspective of synthetic biology.
  In recent years, synthetic biology has been widely applied to engineer and program cellular behaviors. Using this approach, bacteria can be designed to express immunotherapeutic agents, improve tumor targeting, and deliver therapeutic payloads directly to tumo…
  europepmc Xing Liu, Hejin Zhang, Renchun Du, Zixu Liu 等 2026 置信度 0.80
• Opportunities for artificial intelligence and synthetic biology in designing living drug delivery systems.
  Advances in artificial intelligence (AI) and synthetic biology are transforming biological research and biotechnology. These fields are for the first time enabling the design and development of human and bacterial cells that can serve as "living" drug delivery…
  europepmc 2026 置信度 0.80
• Challenges and Future Directives of Synthetic Biology in Engineering Plant-Microbe Partnerships for Sustainable Agriculture.
  Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable cro…
  pubmed Enagbonma BJ, Molefe-Madlaliso RR, Adebayo AA, Oyedoh OP 等 2026 置信度 0.82
• Reimagining colour with synthetic biology.
  europepmc Nick Milne 2025-12-19T05:24:03Z 置信度 0.80
• Bacterial 3D genome architecture: organization, regulation, and synthetic biology applications.
  europepmc Mao Chen, Ziyi Zhu, Yuhuan Huang, Bo Wu 等 2026 置信度 0.80
• Nanofluidics for Pioneering Synthetic Biology of Bottom-Up Cell-Free Molecular Systems.
  Synthetic biology via bottom-up assembly is transitioning from stochastic, extract-based cell-free systems toward reconstituted, molecularly defined cell-free molecular systems. Transitioning to molecularly defined systems provides a path to quantitative desig…
  pubmed Wu S, Ma Q, Takai M, Xu Y 2026 置信度 0.82
• Synthetic biology of oncolytic bacteria: Comparative microbial chassis and precise killing strategies.
  The field of synthetic biology has become a revolutionary tool for engineering microorganisms capable of precise, programmed cancer treatment. Unlike conventional cancer treatments, which lack safe, selective toxicity, engineered microbial cells can detect tum…
  pubmed Hadid MA, Shaikhli NHA, Suhail OK, Hameed ST 等 2026 置信度 0.82
• Synthetic Biology of Sclareol: From the Plant Biosynthetic Pathway to Engineered Microbial and Photosynthetic Chassis.
  Sclareol is a highly valued bicyclic diterpene widely used as a precursor for the fragrance ambroxide and has also attracted interest as a bioactive natural product. Traditional production relies heavily on plant extraction, primarily from Salvia sclarea, an a…
  pubmed Li Y, Ye L, Yu H 2026 置信度 0.82
• Synthetic Biology Strategies for the Development of Live Attenuated Influenza Viruses: Recent Advances and Applications.
  Influenza viruses, due to their simple genomic structure and potent immunostimulatory capacity, have been extensively explored for applications in cancer immunotherapy and viral vector vaccine development. However, wild-type influenza viruses possess inherent …
  pubmed Yang K, Yang G, Xia Y, Ou X 2026 置信度 0.82
• Toward synthetic biology in mushroom-forming Agaricomycete fungi: from tools to applications.
  europepmc 2026 置信度 0.80
• From gene discovery to synthetic biology: recent advances in the biosynthesis of oleanane-type pentacyclic triterpenoids.
  europepmc 2026 置信度 0.80
• A breakthrough in synthetic biology: industrial scaling-up flavonoid C-glycoside production in yeast.
  europepmc 2026 置信度 0.80
• Synthetic biology development of microbial strains for liquid biofuel production.
  europepmc 2026 置信度 0.80
• Synthetic biology as a game-changer for endangered medicinal orchids: biosynthesis, engineering and conservation.
  Covering: 2012 to 2026Medicinal orchids constitute a rich yet vulnerable reservoir of high-value bioactive metabolites. However, their sustainable exploitation is severely hampered by resource depletion and the inefficiency of traditional extraction. Synthetic…
  pubmed Qiu L, Chen X, Luo Z, Jiang M 等 2026 置信度 0.82
• Dual-Chassis Strategy for Bridging Adaptive Evolution and Rational Design for Synthetic Biology
  ABSTRACT Genome streamlining and pathway refactoring are powerful strategies for constructing controllable microbial chassis for both fundamental studies and applications. While rational design benefits from reduced genetic complexity, adaptive laboratory evol…
  europepmc Kesi Kurnia, Isaac Gifford, Ville Santala, Jeffrey E. Barrick 等 2026 置信度 0.80
• Microbial Metabolic Strategies for Environmental Detoxification: From Enzymatic Mechanisms to Synthetic Biology and Omics.
  Microorganisms play a pivotal role in environmental detoxification by utilizing their metabolic pathways to degrade, transform, or immobilize toxic pollutants such as hydrocarbons, heavy metals, pesticides, and industrial effluents. This review explores microb…
  pubmed Pattani V, Kaneriya J, Joshi K, Sanghvi G 2026 置信度 0.82
• Graduate Student Literature Review: Methodologies and tools for synthetic biology for the production of next-generation dairy foods.
  Synthetic biology has played a foundational role in the dairy industry for decades, with continued advancements improving the efficiency, precision, and scalability of producing recombinant dairy foods and additives. As global demand shifts, the industry faces…
  pubmed Madler A, Kennedy K, Morel EF, Brock A 等 2026 置信度 0.82
• Synthetic Biology Approaches to Study Maize Signaling Pathways.
  europepmc 2026 置信度 0.80
• Synthetic Biology for Next-Generation Lactic Acid Bacteria: Engineering the Future of Food.
  Lactic acid bacteria (LAB), as one of the key microorganisms in the food industry, play a crucial role in functional food fermentation. However, current LAB strains are limited by challenges, such as plasmid instability, low gene expression efficiency, and com…
  europepmc 2026 置信度 0.80
• Heterologous expression of anaerobic reductive dehalogenases: host nanoarchitectonics and synthetic biology optimization.
  europepmc 2026 置信度 0.80
• BOTany methods: accessible automation for plant synthetic biology.
  Most members of the synthetic biology community, particularly plant scientists, lack access to liquid handling robots to scale up experiments, enhance reproducibility, and accelerate the Design, Build, Test, Learn cycle. Biofoundries enable high-throughput dat…
  europepmc 2026 置信度 0.80
• Amalgamation of Biofilms and Synthetic Biology: A Paradigm Shift in Biotechnology.
  Biofilms are intricately organized microbial communities enveloped in self-produced extracellular polymeric substances. They display remarkable resilience to environmental and antimicrobial stresses and adhere to various surfaces. Synthetic biology, which comb…
  europepmc 2026 置信度 0.80
• Betacyanin biofortification in wheat via synthetic biology for nutritional enhancement.
  europepmc 2026 置信度 0.80
• Intracellularly coupled oscillators for synthetic biology.
  europepmc 2025 置信度 0.80
• Synthetic biology-driven bioinspired delivery systems for RNA therapeutics in neural repair.
  RNA therapeutics offer transformative potential for neural repair. However, various delivery challenges continue to hinder the clinical translation of RNA therapeutics. Synthetic biology, as an interdisciplinary cutting-edge field, improves delivery systems by…
  europepmc 2026 置信度 0.80
• Synthetic biology-engineered immunotherapies: Precision control of immune responses.
  Immunotherapy has revolutionized the treatment of cancers, infections, and autoimmune disorders by harnessing immune mechanisms such as signal recognition, intracellular cascades, and mediator release. However, clinical translation remains hindered by poor spe…
  europepmc 2026 置信度 0.80
• Employing synthetic biology to modulate metabolic flux: Current strategies and applications.
  europepmc 2026 置信度 0.80
• A high-throughput heterologous expression platform for plant synthetic biology based on Arabidopsis suspension cells.
  europepmc 2026 置信度 0.80
• Synthetic biology for heterologous expression and engineering of fungal polyketide synthases.
  europepmc 2026 置信度 0.80
• Metabolic and Synthetic Biology Strategies for Enhancing Single-Cell Protein Production in Saccharomyces cerevisiae.
  Single cell protein (SCP), distinguished by its high production efficiency, flexible substrate utilization, and excellent nutritional value, has broad application prospects in both feed and food sectors. With the advancement of synthetic biology and metabolic …
  pubmed Wang X, Chen H, Yu H, Ye L 等 2026 置信度 0.82
• From known knowns to unknown unknowns: synthetic biology paths to antimicrobial discovery.
  europepmc 2026 置信度 0.80
• Improving governance in the age of synthetic biology, artificial intelligence, and diverging threats.
  Introduction Advancements in synthetic biology (SynBio) and other emerging and converging technologies, such as artificial intelligence (AI) additive manufacturing (3D printing), and nanotechnology are driving progress at an unprecedented pace. However, these …
  europepmc 2026 置信度 0.80
• Valorizing renewable biomass into potential prebiotic oligosaccharides: Enzymatic, microbial, and synthetic biology strategies.
  europepmc 2026 置信度 0.80
• Chemical and synthetic biology tools to interrogate and control cell-cell interactions in vivo.
  europepmc Tania Baccega, Enrico Dotta, Giulia Pasqual 2026 置信度 0.80
• Synthetic soils for ecological and synthetic biology applications.
  Abstract Soils are heterogeneous and dynamic systems characterized by complex physical, chemical, and biological interactions. Understanding these interactions is critical, as they influence plant productivity, global biogeochemical cycles, and ecosystem resil…
  europepmc Jack Orebaugh, Alyssa A Carrell, Larry M York, Melissa A Cregger 等 2026 置信度 0.80
• Advances in Biomolecular Condensates: From Disease Therapy to Synthetic Biology.
  europepmc 2026 置信度 0.80
• Followers' Choice: The Trends Transforming Precision Medicine, Synthetic Biology, and Sustainable Microbiology.
  The diffusion of science is evolving rapidly, with social networks playing an increasingly essential role. By analysing the journal's accounts on X (@MicrobialBiote1) and BlueSky (@microbiotech.bsky.social), we identified recent microbiology and biotechnology …
  europepmc 2026 置信度 0.80
• Microbial and synthetic biology solutions for waste management and biomanufacturing off Earth.
  Waste management aboard the International Space Station is a critical challenge due to limited space, microgravity, and continuous waste generation. This manuscript explores biotechnological strategies that convert waste into valuable resources, supporting sus…
  europepmc Richa Guleria, Mark A Blenner 2026 置信度 0.80
• Harnessing microalgae for bioproducts: innovations in synthetic biology.
  europepmc 2025 置信度 0.80
• Toward sustainable production of bulnesol and elemol enabled by synthetic biology in Saccharomyces cerevisiae.
  europepmc 2026 置信度 0.80
• Molecular adaptations and engineering of extremophiles for synthetic biology and biotechnological applications.
  europepmc 2026 置信度 0.80
• Omics Technologies-Driven Research and Applications of Synthetic Biology.
  europepmc Dai-Xu Wei, Zheng-Dong Qi, Weixu Cai, Zhimeng Yuan 等 2026 置信度 0.80
• Unveiling the Frontiers of Synthetic Biology in Brazil: Pioneering the National Synthetic Biology Network.
  europepmc 2025 置信度 0.80
• Rewiring holobiont systems with synthetic biology.
  europepmc Jasdeep S. Ghataora, Tom Ellis 2025-10-17T12:10:08Z 置信度 0.80
• Reimagining the Synthetic Biology DBTL Cycle with Machine Learning.
  While progress has been made in developing synthetic regulatory circuits for a variety of applications, circuit engineering remains highly unpredictable due to the inherent complexity of the intracellular medium. With recent advances in high-throughput molecul…
  europepmc Matthew Lee, Yiduo Wang, Kshitij Rai, Shuo Li 等 2026 置信度 0.80
• Reprogramming probiotic for uric acid modular degradation and hyperuricemia treatment by synthetic biology regulation.
  europepmc 2026 置信度 0.80
• DNA Origami and Its Applications in Synthetic Biology.
  europepmc 2026 置信度 0.80
• Chromoproteins: visible tools for advancing synthetic biology.
  europepmc 2026 置信度 0.80
• Tumor-Mimic Artificial Cell Integrated With In Situ Synthetic Biology for Testing of Antitumor Drug Sensitivity.
  europepmc 2026 置信度 0.80
• Phenazine-Based Synthetic Biology to Signal Between Cells and Electrodes.
  europepmc 2026 置信度 0.80
• Synthetic Biology Approaches in Reducing Mycotoxin Contamination and Enhancing Food System Sustainability.
  europepmc 2026 置信度 0.80
• Bottom-Up Synthetic Biology for Artificial Cell Design: From Scaffold Materials to Functional Integration.
  europepmc 2026 置信度 0.80
• Testing AuxInYeast Synthetic Biology Strains via Fluorescence Flow Cytometry.
  europepmc 2026 置信度 0.80