-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
The development of advanced genome engineering tools is crucial for optimizing metabolic pathways in Saccharomyces cerevisiae and achieving efficient biomanufacturing. This study proposes an enhancing multiplex genome editing strategy in S. cerevisiae by emplo…
pubmed
Zheng W, Wang M, Tu Q, Bian X 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2025
置信度 0.80
-
europepmc
2026
置信度 0.80
-
europepmc
2026
置信度 0.80
-
Gibberellic acids (GAs) are a class of tetracyclic diterpene carboxylic acid compounds produced by green plants, fungi, and bacteria, which have a wide range of applications in agricultural production and food ingredients processing. Owing to the continuously …
pubmed
Yin L, Liu X, Chen J, Ding N 等
2026
置信度 0.82
-
europepmc
2026
置信度 0.80
-
The Essence of Metabolic Engineering. Review of Cellular Metabolism. Comprehensive Models for Cellular Reactions. Material Balances and Data Consistency. Regulation of Metabolic Pathways. Examples of Pathway Manipulations: Metabolic Engineering in Practice. Me…
openalex
Gregory Stephanopoulos, Aristos Aristidou, Jens Nielsen
1998-10-16
置信度 0.72
Metabolic flux analysisMetabolic engineeringMetabolic pathwayMetabolic networkFlux (metallurgy)
-
Application of recombinant DNA methods to restructure metabolic networks can improve production of metabolite and protein products by altering pathway distributions and rates. Recruitment of heterologous proteins enables extension of existing pathways to obtai…
openalex
James E. Bailey
1991-06-21
置信度 0.72
Metabolic engineeringHeterologousMetabolic pathwayProtein engineeringComputational biology
-
Summary Plants synthesize an amazing diversity of volatile organic compounds ( VOC s) that facilitate interactions with their environment, from attracting pollinators and seed dispersers to protecting themselves from pathogens, parasites and herbivores. Recent…
openalex
Natalia Dudareva, Antje Klempien, Joëlle K. Mühlemann, Ian Kaplan
2013-02-06
置信度 0.72
Metabolic engineeringSecondary metabolismPollinatorBiologyMetabolic pathway
-
Poly(3-hydroxyalkanoates) (PHAs) are a class of microbially produced polyesters that have potential applications as conventional plastics, specifically thermoplastic elastomers. A wealth of biological diversity in PHA formation exists, with at least 100 differ…
openalex
Lara L. Madison, Gjalt W. Huisman
1999-03-01
置信度 0.72
PolyhydroxyalkanoatesMetabolic engineeringOrganismSynthetic biologyBiology
-
Metabolic engineering has the potential to produce from simple, readily available, inexpensive starting materials a large number of chemicals that are currently derived from nonrenewable resources or limited natural resources. Microbial production of natural p…
openalex
Jay D. Keasling
2010-12-02
置信度 0.72
Metabolic engineeringBiochemical engineeringSpeciality chemicalsSynthetic biologyMetabolic pathway
-
openalex
Harry Yim, Robert J. Haselbeck, Wei Niu, Catherine Pujol-Baxley 等
2011-05-22
置信度 0.72
Metabolic engineeringEscherichia coliCommodity chemicals2,3-ButanediolXylose
-
openalex
Gregory Stephanopoulos
1999-01-01
置信度 0.72
Metabolic engineeringMetabolic control analysisMetabolic flux analysisMetabolic pathwayFlux (metallurgy)
-
openalex
Charles E Nakamura, Gregory M. Whited
2003-09-16
置信度 0.72
1,3-PropanediolMetabolic engineeringProduction (economics)Biochemical engineeringRaw material
-
openalex
Kyeong Rok Choi, Woo Dae Jang, Dongsoo Yang, Jae Sung Cho 等
2019-02-05
置信度 0.72
Metabolic engineeringSynthetic biologyBioproductsSystems biologyBiochemical engineering
-
Abiotic stresses including drought, salinity, heat, cold, flooding, and ultraviolet radiation causes crop losses worldwide. In recent times, preventing these crop losses and producing more food and feed to meet the demands of ever-increasing human populations …
openalex
Shabir Hussain Wani, Vinay Kumar, Varsha Shriram, Saroj Kumar Sah
2016-04-03
置信度 0.72
Abiotic componentAbiotic stressBiologyCropAgriculture
-
openalex
Richard A. F. Dixon, Christopher L. Steele
1999-10-01
置信度 0.72
IsoflavonoidFlavonoidBiologyFlavonoid biosynthesisNatural product
-
openalex
Jeong Wook Lee, Dokyun Na, Jong Myoung Park, Joungmin Lee 等
2012-05-17
置信度 0.72
Metabolic engineeringSynthetic biologyBiochemical engineeringSystems biologyMetabolic pathway
-
openalex
Josefina Zaldivar, Jens Nielsen, Lennart Olsson
2001-07-01
置信度 0.72
Zymomonas mobilisBiofuelEthanol fuelBiomass (ecology)Metabolic engineering
-
openalex
Gang Wu, Qiang Yan, J. Andrew Jones, Yinjie Tang 等
2016-03-18
置信度 0.72
Synthetic biologyMetabolic engineeringBiochemical engineeringComputational biologyBiotechnology
-
openalex
Shota Atsumi, Anthony F. Cann, Michael R. Connor, Claire R. Shen 等
2007-09-15
置信度 0.72
ButanolEscherichia coliMetabolic engineeringFermentationClostridium
-
The traditional use of the yeast Saccharomyces cerevisiae in alcoholic fermentation has, over time, resulted in substantial accumulated knowledge concerning genetics, physiology, and biochemistry as well as genetic engineering and fermentation technologies. S.…
openalex
Elke Nevoigt
2008-09-01
置信度 0.72
Metabolic engineeringSaccharomyces cerevisiaeYeastBiochemical engineeringBiology
-
openalex
Seyed Mohammad Nabavi, Seyed Mohammad Nabavi, Dunja Šamec, Michał Tomczyk 等
2018-11-17
置信度 0.72
Metabolic engineeringMetabolic pathwayBiologyShikimic acidBiosynthesis
-
openalex
Jens Nielsen
2001-04-01
置信度 0.72
Metabolic engineeringBiochemical engineeringMetabolic pathwayFunction (biology)Synthetic biology
-
openalex
Tony H.H Chen, Norio Murata
2002-06-01
置信度 0.72
Abiotic stressBiologyAbiotic componentProlineOsmoprotectant
-
BACKGROUND: Through genetic engineering it is possible to introduce targeted genetic changes and hereby engineer the metabolism of microbial cells with the objective to obtain desirable phenotypes. However, owing to the complexity of metabolic networks, both i…
openalex
Kiran Raosaheb Patil, Isabel Rocha, Jochen Förster, Jens Nielsen
2005-12-23
置信度 0.72
Metabolic engineeringFlux balance analysisComputer scienceSystems biologyComputational biology
-
In order to enhance the yield and productivity of metabolite production, researchers have focused almost exclusively on enzyme amplification or other modifications of the product pathway. However, overproduction of many metabolites requires significant redirec…
openalex
Gregory Stephanopoulos, Joseph J. Vallino
1991-06-21
置信度 0.72
OverproductionMetaboliteMetabolic engineeringRigidity (electromagnetism)Flux (metallurgy)
-
Comprehensive knowledge regarding Saccharomyces cerevisiae has accumulated over time, and today S. cerevisiae serves as a widley used biotechnological production organism as well as a eukaryotic model system. The high transformation efficiency, in addition to …
openalex
Simon Østergaard, Lisbeth Olsson, Jens Nielsen
2000-03-01
置信度 0.72
Saccharomyces cerevisiaeBiologyOrganismMetabolic engineeringSynthetic biology
-
openalex
Dokyun Na, Seung Min Yoo, Hannah Chung, Hyegwon Park 等
2013-01-20
置信度 0.72
Escherichia coliSynthetic biologyBiologyGeneMetabolic engineering
-
MOTIVATION: The simulation of biochemical kinetic systems is a powerful approach that can be used for: (i) checking the consistency of a postulated model with a set of experimental measurements, (ii) answering 'what if?' questions and (iii) exploring possible …
openalex
Pedro Mendes, Douglas B. Kell
1998-01-01
置信度 0.72
Computer scienceMetabolic engineeringEstimationEstimation theoryComputational biology
-
openalex
Jay D. Keasling
2012-02-01
置信度 0.72
Metabolic engineeringSynthetic biologyComputational biologyArtemisininBiology
-
openalex
Sammy Pontrelli, Tsan‐Yu Chiu, Ethan I. Lan, Frederic Y.-H. Chen 等
2018-04-22
置信度 0.72
Escherichia coliMetabolic engineeringSynthetic biologyBiologyHost (biology)
-
Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine o…
openalex
Kwang Ho Lee, Jin Hwan Park, Tae Yong Kim, Hyun Uk Kim 等
2007-12-04
置信度 0.72
Metabolic engineeringEscherichia coliBiologyThreonineTranscriptome
-
openalex
Asaph Aharoni, Maarten A. Jongsma, Harro J. Bouwmeester
2005-11-15
置信度 0.72
TerpenoidMetabolic engineeringBiologyMetabolic pathwayPlant metabolism
-
openalex
Zhixiong Xue, Pamela L. Sharpe, Seung Pyo Hong, Narendra Singh Yadav 等
2013-07-21
置信度 0.72
YarrowiaEicosapentaenoic acidDocosahexaenoic acidMetabolic engineeringFood science
-
openalex
Jay J. Thelen, John B. Ohlrogge
2002-01-01
置信度 0.72
Metabolic engineeringFatty acidGenetically modified cropsBiotechnologyBiosynthesis
-
openalex
Marina Kalyuzhnaya, Aaron W. Puri, Mary E. Lidstrom, Marina G. Kalyuzhnaya
2015-04-08
置信度 0.72
MethaneBioconversionMetabolic engineeringBiochemical engineeringBiogas
-
openalex
Thomas W. Jeffries, Yong‐Su Jin
2004-01-28
置信度 0.72
XylosePichia stipitisXylitolXylose metabolismBiochemistry
-
openalex
Stefan Schuster, S Schuster
1999-02-01
置信度 0.72
Metabolic engineeringFlux (metallurgy)Pathway analysisComputational biologyMetabolic network
-
The ethanol-producing bacterium Zymomonas mobilis was metabolically engineered to broaden its range of fermentable substrates to include the pentose sugar xylose. Two operons encoding xylose assimilation and pentose phosphate pathway enzymes were constructed a…
openalex
Min Zhang, C K Eddy, Kristine Deanda, Mark Finkelstein 等
1995-01-13
置信度 0.72
Zymomonas mobilisPentoseXylosePentose phosphate pathwayFermentation
-
We present here a broad overview of the field of metabolic engineering, describing in the first section the key fundamental principles that define and distinguish it, as well as the technological and intellectual developments over the past approximately 20 yea…
openalex
Benjamin M. Woolston, Steven Edgar, Gregory Stephanopoulos
2013-03-29
置信度 0.72
Metabolic engineeringMetabolic flux analysisField (mathematics)Computer scienceData science
-
Natural products and their derivatives play an important role in modern healthcare as frontline treatments for many diseases and as inspiration for chemically synthesized therapeutics. With advances in sequencing and recombinant DNA technology, many of the bio…
openalex
Lauren B. Pickens, Yi Tang, Yit‐Heng Chooi
2011-03-02
置信度 0.72
Metabolic engineeringSynthetic biologyNatural productBiochemical engineeringComputational biology
-
openalex
Denis Rontein, Gilles J. Basset, Andrew D. Hanson, Gilles Basset
2002-01-01
置信度 0.72
OsmoprotectantEctoineTrehaloseBiologyBiochemistry
-
Hypocrea jecorina (= Trichoderma reesei) is the main industrial source of cellulases and hemicellulases used to depolymerise plant biomass to simple sugars that are converted to chemical intermediates and biofuels, such as ethanol. Cellulases are formed adapti…
openalex
Christian P. Kubicek, M. Mikus, André Schuster, Monika Schmoll 等
2009-01-01
置信度 0.72
HypocreaCellulaseTrichoderma reeseiBiomass (ecology)Biotechnology
-
BACKGROUND: Increasing energy costs and environmental concerns have motivated engineering microbes for the production of "second generation" biofuels that have better properties than ethanol. RESULTS AND CONCLUSION: Saccharomyces cerevisiae was engineered with…
openalex
Eric J. Steen, Rossana Chan, Nilu Prasad, Samuel A. Myers 等
2008-12-01
置信度 0.72
Clostridium beijerinckiiButanolMetabolic engineeringEscherichia coliBiochemistry
-
Besides its use for efficient production of recombinant proteins the methylotrophic yeast Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to produce metabolites of varying origin. We summarize here the impressive methodolo…
openalex
David A. Peña, Brigitte Gasser, Jürgen Zanghellini, Matthias G. Steiger 等
2018-04-25
置信度 0.72
Pichia pastorisMetabolic engineeringSynthetic biologyHeterologousComputational biology
-
The ecological footprint and economic performance of the current suite of biofuel production methods make them insufficient to displace fossil fuels and reduce their impact on the inventory of Green House Gas (GHG) in the global atmosphere. Algae metabolic eng…
openalex
Jing Lü, Con Sheahan, Pengcheng Fu
2011-01-01
置信度 0.72
BiofuelBiomass (ecology)Cellulosic ethanolAlgaeFossil fuel
-
openalex
Judith Becker, Oskar Zelder, Stefan S. Hafner, Hartwig Schröder 等
2011-01-18
置信度 0.72
Corynebacterium glutamicumMetabolic engineeringLysineStrain (injury)In silico
-
Metabolic engineering emerged 20 years ago as the discipline occupied with the directed modification of metabolic pathways for the microbial synthesis of various products. As such, it deals with the engineering (design, construction, and optimization) of nativ…
openalex
Gregory Stephanopoulos
2012-11-01
置信度 0.72
Synthetic biologyMetabolic engineeringContext (archaeology)Systems biologyBiochemical engineering
-
openalex
Yifan Li, Zhenquan Lin, Can Huang, Yan Zhang 等
2015-07-03
置信度 0.72
CRISPRGenome editingMetabolic engineeringGenome engineeringCas9
-
Machine learning provides researchers a unique opportunity to make metabolic engineering more predictable. In this review, we offer an introduction to this discipline in terms that are relatable to metabolic engineers, as well as providing in-depth illustrativ…
openalex
Christopher E. Lawson, Jose Manuel Martí, Tijana Radivojević, Sai Vamshi R. Jonnalagadda 等
2020-11-19
置信度 0.72
Metabolic engineeringComputer scienceVariety (cybernetics)Data scienceFactory (object-oriented programming)
-
openalex
Jens Nielsen, Christer Larsson, Antonius Van Maris, Jack T. Pronk
2013-04-22
置信度 0.72
Metabolic engineeringBiofuelBiochemical engineeringRenewable energyBiotechnology
-
openalex
Dongsoo Yang, Seon Young Park, Yae Seul Park, Hyunmin Eun 等
2020-01-07
置信度 0.72
Escherichia coliMetabolic engineeringBiosynthesisChemistryNatural product
-
Summary Lignin, a phenolic polymer in the secondary wall, is the major cause of lignocellulosic biomass recalcitrance to efficient industrial processing. From an applications perspective, it is desirable that second‐generation bioenergy crops have lignin that …
openalex
Ruben Vanholme, Kris Morreel, Chiarina Darrah, Paula Oyarce 等
2012-10-04
置信度 0.72
MonolignolLigninChemistryMetabolic engineeringBiofuel
-
alpha-Tocopherol (vitamin E) is a lipid-soluble antioxidant synthesized only by photosynthetic organisms. alpha-Tocopherol is an essential component of mammalian diets, and intakes in excess of the U.S. recommended daily allowance are correlated with decreased…
openalex
David K. Shintani, Dean DellaPenna
1998-12-11
置信度 0.72
Vitamin ETocopherolBiochemistryAntioxidantArabidopsis
-
openalex
Yechun Wang, Steven Chen, Oliver Yu
2011-07-05
置信度 0.72
Metabolic engineeringFlavonoidBioconversionOrganismFlavonoid biosynthesis
-
Sustainable production of chemicals from renewable non-food biomass has become a promising alternative to overcome environmental issues caused by our heavy dependence on fossil resources. Systems metabolic engineering, which integrates traditional metabolic en…
openalex
Yoo‐Sung Ko, Je Woong Kim, Jong An Lee, Tae-Hee Han 等
2020-01-01
置信度 0.72
Metabolic engineeringBiochemical engineeringProduction (economics)BiotechnologyComputer science
-
openalex
Jorge Alonso-Gutiérrez, Rossana Chan, Tanveer S. Batth, Paul D. Adams 等
2013-05-29
置信度 0.72
Metabolic engineeringEscherichia coliAlcoholLimoneneProduction (economics)
-
openalex
Kuk-Ki Hong, Jens Nielsen
2012-03-03
置信度 0.72
Metabolic engineeringBiochemical engineeringSynthetic biologyBiofuelBiomass (ecology)
-
openalex
Thomas Becker, Richard J. Noel, Ward Coats, Anna M. Gómèz‐Foix 等
1994-01-01
置信度 0.72
BiologyRecombinant DNAVirusVirologyViral vector
-
BACKGROUND: Over the last few years a number of methods have been proposed for the phenotype simulation of microorganisms under different environmental and genetic conditions. These have been used as the basis to support the discovery of successful genetic mod…
openalex
Isabel Rocha, Paulo Maia, Pedro Evangelista, Paulo Vilaça 等
2010-04-19
置信度 0.72
SBMLFlux balance analysisComputer scienceMetabolic engineeringMetabolic flux analysis
-
openalex
Anastasia Krivoruchko, Yiming Zhang, Verena Siewers, Yun Chen 等
2014-12-06
置信度 0.72
Metabolic engineeringMetabolismMicrobial metabolismBiochemistryChemistry
-
Industrial biotechnology and microbial metabolic engineering are poised to help meet the growing demand for sustainable, low-cost commodity chemicals and natural products, yet the fraction of biochemicals amenable to commercial production remains limited. Comm…
openalex
Quentin M. Dudley, Ashty S. Karim, Michael C. Jewett
2014-10-15
置信度 0.72
BiomanufacturingMetabolic engineeringBiochemical engineeringBioconversionSynthetic biology
-
openalex
Natalia Dudareva, Eran Pichersky
2008-04-01
置信度 0.72
Metabolic engineeringAromaBiotechnologyBiologyMetabolic pathway
-
Arabidopsis thaliana is the first model plant, the genome of which has been sequenced. In general, intensive studies on this model plant over the past nearly 30 years have led to many new revolutionary understandings in every single aspect of plant biology. He…
openalex
Ming-Zhu Shi, De‐Yu Xie
2014-04-01
置信度 0.72
Arabidopsis thalianaMYBArabidopsisAnthocyaninBiology
-
openalex
Vikramaditya G. Yadav, Marjan De Mey, Chin Giaw Lim, Parayil Kumaran Ajikumar 等
2012-02-15
置信度 0.72
Metabolic engineeringSynthetic biologyBiochemical engineeringModular designBiotechnology
-
openalex
Bärbel Hahn‐Hägerdal, Kaisa Karhumaa, Marie Jeppsson, Marie F. Gorwa‐Grauslund
2007-05-11
置信度 0.72
PentosePentose phosphate pathwaySaccharomyces cerevisiaeYeastMetabolic engineering
-
openalex
Jiazhang Lian, Shekhar Mishra, Huimin Zhao
2018-04-25
置信度 0.72
Metabolic engineeringGenome engineeringSaccharomyces cerevisiaeCRISPRComputational biology
-
Development of renewable energy is rapidly being embraced by our society and industry to achieve the nation's economic growth goals and to help address the world's energy and global warming crises. Currently most of the bioethanol production is from the fermen…
openalex
Jason Dexter, Pengcheng Fu
2009-01-01
置信度 0.72
Zymomonas mobilisPyruvate decarboxylaseBiofuelSynechocystisAlcohol dehydrogenase
-
Metabolic engineering aims to improve the production of economically valuable molecules through the genetic manipulation of microbial metabolism. While the discipline is a little over 30 years old, advancements in metabolic engineering have given way to indust…
openalex
Michael Volk, Vinh Tran, Shih‐I Tan, Shekhar Mishra 等
2022-12-30
置信度 0.72
Metabolic engineeringBiochemical engineeringRobustness (evolution)ChemistrySynthetic biology
-
openalex
Haoran Zhang, Xiaonan Wang
2016-05-28
置信度 0.72
BioproductionMetabolic engineeringModular designScope (computer science)Biochemical engineering
-
openalex
Volker F. Wendisch
2019-03-30
置信度 0.72
Amino acidMetabolic engineeringBiochemistryLysineHydroxylation
-
openalex
Sergei Storozhenko, Veerle De Brouwer, Maarten Volckaert, Oscar Navarrete 等
2007-10-14
置信度 0.72
BiofortificationPterinMicronutrientFortificationFood fortification
-
openalex
Giovanni Giuliano, Raffaela Tavazza, Gianfranco Diretto, Peter Beyer 等
2008-01-30
置信度 0.72
CarotenoidMetabolic engineeringBiologyAbiotic stressBiotechnology
-
openalex
Kathleen A. Curran, John M. Leavitt, Ashty S. Karim, Hal S. Alper
2012-11-16
置信度 0.72
Muconic acidAdipic acidBiochemistrySaccharomyces cerevisiaeMetabolic engineering
-
openalex
Tina Lütke‐Eversloh, Hubert Bahl
2011-03-05
置信度 0.72
Clostridium acetobutylicumClostridiaButanolClostridiumMetabolic engineering
-
openalex
S. Andreas Angermayr, Aleix Gorchs Rovira, Klaas J. Hellingwerf
2015-04-21
置信度 0.72
Metabolic engineeringCommodity chemicalsCarbon fixationPhotosynthesisBioplastic
-
T. M. Kutchan; Alkaloid Biosynthesis—The Basis for Metabolic Engineering of Medicinal Plants., The Plant Cell, Volume 7, Issue 7, 1 July 1995, Pages 1059–1070,
openalex
Toni M. Kutchan
1995-07-01
置信度 0.72
BiologyBiosynthesisAlkaloidMetabolic engineeringBotany
-
openalex
Robert Verpoorte, A. W. Alfermann
2000-01-01
置信度 0.72
Metabolic engineeringPlant metabolismMetabolismSecondary metabolismBiology
-
openalex
Pyung Cheon Lee, Claudia Schmidt‐Dannert
2002-10-01
置信度 0.72
CarotenoidMetabolic engineeringBiologyMicroorganismNutraceutical
-
openalex
Vasiliy A. Portnoy, Daniela Bezdan, Karsten Zengler
2011-04-20
置信度 0.72
Metabolic engineeringSynthetic biologyDirected evolutionAdaptive evolutionBiochemical engineering
-
Thanks to the rapid progress in molecular biology of flavonoid biosynthesis and plant transformation, it has become feasible to modify the pathway and flower color through genetic engineering. One of the advantages of molecular breeding is that flower color ca…
openalex
Yoshikazu Tanaka, Shinzo Tsuda, Takaaki Kusumi
1998-11-01
置信度 0.72
Biological systemBiologyComputer scienceBotanyChemistry
-
openalex
Ming‐Hua Liang, Jian‐Guo Jiang
2013-05-16
置信度 0.72
Metabolic engineeringBiodieselBiofuelMicroorganismBiomass (ecology)
-
openalex
Alexander Steinbüchel, Tina Lütke‐Eversloh
2003-03-25
置信度 0.72
PolyhydroxyalkanoatesMetabolic engineeringBioplasticBiochemistryProtein engineering
-
openalex
Ahmad Mohammad Abdel‐Mawgoud, Kelly A. Markham, Claire M. Palmer, Nian Liu 等
2018-07-26
置信度 0.72
YarrowiaMetabolic engineeringOrganismYeastBiology
-
openalex
Seok Hyun Park, Hyun Uk Kim, Tae Yong Kim, Junseok Park 等
2014-08-05
置信度 0.72
Corynebacterium glutamicumMetabolic engineeringArginineBiochemistryFermentation
-
Plant alkaloids, one of the largest groups of natural products, provide many pharmacologically active compounds. Several genes in the biosynthetic pathways for scopolamine, nicotine, and berberine have been cloned, making the metabolic engineering of these alk…
openalex
Fumihiko Sato, Takashi Hashimoto, Akira Hachiya, Ken‐ichi Tamura 等
2000-12-26
置信度 0.72
BenzylisoquinolineAlkaloidAtropa belladonnaBerberineMetabolic engineering