-
Recent advancements in deep learning (DL) have propelled the virtual transformation of microscopy images across optical modalities, enabling unprecedented multimodal imaging analysis hitherto impossible. Despite these strides, the integration of such algorithm…
openalex
Dana Hassan, Jesús Domínguez, Benjamin Midtvedt, Henrik Klein Moberg 等
2024-11-27
置信度 0.72
Modality (human–computer interaction)MicroscopyArtificial intelligenceComputer scienceMedicine
-
Micro- and nanoplastics can interact with various biologically active compounds forming aggregates of which the effects have yet to be understood. To this end, it is vital to characterize these aggregates of key compounds and micro- and nanoplastics. In this s…
openalex
Leonard Dick, Patrick R. Batista, Paul Zaby, Gabriele Manhart 等
2024-10-28
置信度 0.72
TetracyclineAdsorptionPolypropylenePolyethylenePolymer
-
openalex
Vernon Riley, Joseph G. Fortner
1963-01-01
置信度 0.72
PigmentComputational biologyBiologyChemistryOrganic chemistry
-
The rise of neuromorphic systems has addressed the shortcomings of current computing architectures, especially regarding energy efficiency and scalability. These systems use cutting-edge technologies such as Pt/SnO x /TiN memristors, which efficiently mimic sy…
openalex
Dongyeol Ju, Sungjun Kim
2024-07-09
置信度 0.72
Neuromorphic engineeringMemristorScalabilityTinComputer science
-
Abstract The control of phytoplankton production by tidal forcing in the Alboran Sea is investigated with a high‐resolution ocean circulation model coupled to an ecosystem model. The aim of the modeling efforts was to elucidate the role of tides in sustaining …
openalex
José Carlos Sánchez-Garrido, Cristina Naranjo, Diego Macías, Jesús García‐Lafuente 等
2015-10-23
置信度 0.72
OceanographyPhytoplanktonProductivityPhotic zoneEnvironmental science
-
Biological valve failure (BVF) is an inevitable condition that compromises the durability of biological heart valves (BHVs). It stems from various causes, including rejection, thrombosis, and endocarditis, leading to a critical state of valve dysfunction. Echo…
openalex
Fabio Fazzari, Andrea Baggiano, Laura Fusini, Sarah Ghulam Alì 等
2023-09-03
置信度 0.72
MedicineDegeneration (medical)EndocarditisThrombosisCardiology
-
crossref
2023-11-27T04:06:05Z
置信度 0.70
-
crossref
2024-05-27T09:17:18Z
置信度 0.70
-
crossref
2024-01-03T05:02:57Z
置信度 0.70
-
crossref
Wireless Communications and Mobile Computing
2024-09-18T03:43:38Z
置信度 0.70
-
Now that the global population has reached eight billion, a huge number of humans and other living organisms are struggling to coexist harmoniously, which affects the sustainable development of the world. Humanity is facing three major environmental problems: …
crossref
Hai Ren
2024-03-12T17:28:46Z
置信度 0.70
-
crossref
Alejandro Sirvent Llamas, José Luis Albentosa Mora, Higinio Mora, Zuleika Redondo 等
2024-12-20T02:01:33Z
置信度 0.70
-
sentiment analysis using CNN and GRU deep learning algorithms 665970
crossref
2024-03-04T19:01:09Z
置信度 0.70
-
This paper focuses on the maximum speed at which biological evolution can occur.I derive inequalities that limit the rate of evolutionary processes driven by natural selection, mutations, or genetic drift.These rate limits link the variability in a population …
crossref
Luis Garcia-Pintos Barcia
2024-06-27T22:13:57Z
置信度 0.70
-
crossref
Wireless Communications and Mobile Computing
2024-09-18T03:42:00Z
置信度 0.70
-
crossref
2024-03-04T19:11:54Z
置信度 0.70
-
crossref
2024-04-29T05:10:55Z
置信度 0.70
-
crossref
2024-07-08T09:14:50Z
置信度 0.70
-
crossref
2024-06-10T09:35:42Z
置信度 0.70
-
crossref
2024-01-24T20:03:49Z
置信度 0.70
-
crossref
2024-07-22T09:19:20Z
置信度 0.70
-
crossref
2024-03-25T09:13:38Z
置信度 0.70
-
crossref
2024-01-12T01:42:50Z
置信度 0.70
-
crossref
2024-08-19T09:11:34Z
置信度 0.70
-
Neuromorphic computing represents a groundbreaking paradigm shift in the realm of artificial intelligence, aiming to replicate the architecture and operational mechanisms of the human brain. This paper provides a comprehensive exploration of the foundational p…
crossref
Rajeev Borra
2024-12-24T23:41:37Z
置信度 0.70
-
crossref
2024-07-29T12:38:24Z
置信度 0.70
-
crossref
2023-12-11T04:03:47Z
置信度 0.70
-
crossref
2024-03-25T09:13:14Z
置信度 0.70
-
In everyday parlance "development" and "progress" are almost interchangeable terms.However, evaluating development within the framework of the North East is a rhetorical device that gives rise to the idea of "underdevelopment."The region may have reached a lev…
crossref
2024-08-01T07:19:28Z
置信度 0.70
-
crossref
2024-08-09T12:46:53Z
置信度 0.70
-
crossref
Ebrahim Maghami, Ahmad Najafi
2023-12-12T21:02:10Z
置信度 0.70
-
crossref
2024-07-08T09:14:44Z
置信度 0.70
-
Preeclampsia is a serious condition affecting 2-4% of pregnancies globally. However, it is more common in pregnancies with diabetes (e.g. 10-20% in Type 1 diabetes) than in pregnancies without diabetes. In the general population, higher maternal fasting glucos…
preprints
2025
置信度 0.74
-
Current long-read single-nucleotide variant callers were designed primarily for genomic data—particularly human genomes. While some have been used on metagenomic data, their underlying assumptions and training procedures fail to account for the inherent comple…
preprints
2025
置信度 0.74
-
The red fluorescent protein mCherry is one of the most utilised fluorescent proteins in biology. Here, we have changed the chromophore chemistry by converting the thioether group of M66 to a thiol group through mutation to cysteine. The new variant termed mCor…
preprints
2025
置信度 0.74
-
Machine learning increasingly uncovers rules of biology directly from data, enabled by large, standardized datasets. Microscopy images provide rich information on cellular architecture and are accessible at scale across biological systems, making them an ideal…
preprints
2025
置信度 0.74
-
The neural information organizing and processing principles are presented in a general transdisciplinary axiomatic form, highlighting the fundamental neural informational characteristics and processes as a guiding informational synthesis useful in various fiel…
preprints
2025
置信度 0.74
-
Abstract We present the first quantum-centric simulations of noncovalent interactions using a supramolecular approach. We simulate the potential energy surfaces (PES) of the water and methane dimers, featuring hydrophilic and hydrophobic interactions, respecti…
preprints
2025
置信度 0.74
-
Environmental DNA (eDNA) metabarcoding has become increasingly popular as an approach to efficiently document biodiversity within an environment characterized by relative uncertainty. Compared to the traditional stereomicroscopic approaches, eDNA metabarcoding…
preprints
2025
置信度 0.74
-
One of the most studied attributes of mental activity is intelligence. While non-human consciousness remains a subject of profound debate, non-human intelligence is universally acknowledged by all participants of discussion as a necessary element of any consci…
preprints
2025
置信度 0.74
-
ABSTRACT Foundation models trained on electronic healthcare records (EHRs) have gained traction with the aim to transform personalised medicine. However, their interpretability is bound to redescribing the records the models were trained on, missing implicitly…
preprints
2026
置信度 0.74
-
Association studies have linked many genetic variants to a variety of phenotypes but understanding the biological mechanisms underlying these signals remains a major challenge. Since genes operate within complex networks, statistical interactions between genet…
preprints
2025
置信度 0.74
-
This comprehensive study examines the revolutionary integration of AR Thermodynamics systems with the Myriad Cylinder Diagnostic Patch and Device, representing a significant advancement in portable diagnostic technology. The system combines specialized thermal…
preprints
2025
置信度 0.74
-
ABSTRACT Astrocytes are increasingly recognized as active participants in sensory processing, but whether they show selective responses to stimulus features, analogous to neuronal receptive fields, is not yet established. To address this, we used two-photon ca…
preprints
2025
置信度 0.74
-
ABSTRACT Skeletal muscle displays remarkable plasticity, adapting its size and strength in response to mechanical loading, particularly, from exercise. This process, known as hypertrophy, is fundamental to athletic training and rehabilitation, but is challengi…
preprints
2025
置信度 0.74
-
Background Multiplexed tissue imaging enables the simultaneous detection of dozens of proteins at single-cell resolution, providing unprecedented insights into tissue organization and disease microenvironments. However, the resulting high-dimensional, gigabyte…
preprints
2025
置信度 0.74
-
Schizophrenia spectrum disorders (SSDs) are clinically and neurobiologically heterogeneous. Normative modeling addresses heterogeneity of structural brain alterations by focusing on individual-level deviations, but their clinical relevance in SSDs remains cont…
preprints
2026
置信度 0.74
-
As more powerful high performance computing resources are becoming available, there is a new opportunity to bring the unique capabilities of molecular dynamics (MD) simulations to cell-scale systems. Membranes are ubiquitous within cells and are responsible fo…
preprints
2025
置信度 0.74
-
Abstract The G2PDeep-v2 server is a web-based platform powered by deep learning, for phenotype prediction and markers discovery from multi-omics data in any organisms including humans, plants, animals, and viruses. The server provides multiple services for res…
preprints
2025
置信度 0.74
-
Allosteric effects are widespread in proteins, but predicting the impact of sequence substitutions at positions distant from ligand-binding or enzyme active sites remains challenging, as their effects are mediated through complex dynamical networks. Pinpointin…
preprints
2025
置信度 0.74
-
The evolutionary conservation of cell types over deep time has long been theorised but remains difficult to demonstrate. Monoaminergic neurons, which produce molecules such as serotonin and dopamine, are central to animal behaviour and cognition, yet their evo…
preprints
2025
置信度 0.74
-
Abstract Deep learning has established itself as the state-of-the-art approach for segmentation in bioimage analysis. However, these powerful algorithms present an intriguing paradox regarding image resolution: contrary to intuition, lower-resolution images ca…
preprints
2025
置信度 0.74
-
Single-cell sequencing technologies offer unprecedented resolution to inspect transcriptomes and generate critical biological insights. As the number of cells and cell types increase in single-cell studies, the effort required to analyze the data surges dramat…
preprints
2025
置信度 0.74
-
Background The polychaete Capitella teleta is a commonly used annelid for studies in evolutionary developmental biology, comparative genomics, conservation, and ecotoxicology. Over a decade ago, it was the first polychaete to have its genome sequenced and asse…
preprints
2025
置信度 0.74
-
Abstract Cognitive deficits are common across many neurodevelopmental and psychiatric conditions, including those studied in the current set of PGC-CNV papers. How changes in regional gene expression across the cerebral cortex influence cognitive ability remai…
preprints
2025
置信度 0.74
-
Summary Dynamic models are useful to study processes ranging from cell signalling to cell differentiation. Common modelling workflows such as model exploration and parameter estimation are computationally demanding. The Julia programming language is a promisin…
preprints
2025
置信度 0.74
-
Applications of artificial intelligence (AI) to histopathology are now common, but most require supervision which inherently limits their scope. By using self-supervised learning (SSL), we discover and quantify the full range of histopathological appearances i…
preprints
2025
置信度 0.74
-
Circulating hormones, that mediate communications across organs to maintain physiological balance, are commonly detected and quantified using enzyme-linked immunosorbent assays (ELISAs). However, while ELISA is well-suited for organisms where sample blood can …
preprints
2025
置信度 0.74
-
Humans are experts at recognizing faces, yet this expertise is not uniform: people perceive faces from familiar facial groups more accurately than those from unfamiliar ones—a phenomenon known as the Other-Race Effect (ORE). Diverse facial exposure mitigates t…
preprints
2025
置信度 0.74
-
X-ray phase contrast tomography is emerging as a powerful method for imaging large volumes of brain tissue at sub-cellular resolution. However, current sample preparation methods are largely inherited from visible light or electron microscopy workflows and hen…
preprints
2025
置信度 0.74
-
ABSTRACT Conjugative transfer of plasmids represents a major route through which antibiotic resistance genes are spread. In the case of the prevalent and deadly pathogen Staphylococcus aureus , >90% of clinical isolates carry at least one plasmid. While plasmi…
preprints
2025
置信度 0.74
-
Cardiovascular diseases (CVDs) frequently co-occur, yet the shared genetic basis of cardiovascular multimorbidity remains unclear. We analysed common- and rare-variant genetic overlap across eight major CVDs using genome-wide and exome-wide association data fr…
preprints
2026
置信度 0.74
-
The recent discovery that mutations in the Plasmodium falciparum genome are overrepresented in infections of sickle haemoglobin (HbS)-carriers has highlighted new questions about the underlying biological and evolutionary interaction, yet the full extent of th…
preprints
2025
置信度 0.74
-
Abstract Atherosclerotic cardiovascular disease shows a marked male predominance(1–3), yet the biological basis for this disparity remains unclear. Mosaic loss of chromosome Y (LOY) in blood – a common, acquired and age associated mutation(4,5)- has been linke…
preprints
2026
置信度 0.74
-
Deep learning has established itself as the state-of-the-art approach for segmentation in bioimage analysis. However, these powerful algorithms present an intriguing paradox regarding image resolution: contrary to intuition, lower-resolution images can yield s…
preprints
2025
置信度 0.74
-
The aging process is characterized by a general decrease in physical functionality and poses the biggest risk factor for a variety of diseases such as cancer, cardiovascular diseases, and neurodegenerative disorders among others. Understanding the naturally ev…
preprints
2025
置信度 0.74
-
In recent years, unconventional computing architectures that transcend traditional semiconductor-based systems have witnessed far-ranging research interest. Here we propose an approach to the construction of logic gates, using active particles, specifically 1-…
europepmc
2025
置信度 0.80
-
Protein glycosylation is a critical post-translational modification involved in numerous biological processes and disease states. While mass spectrometry has emerged as the primary tool for glycoproteomics analysis, the structural complexity and heterogeneity …
europepmc
2025
置信度 0.80
-
The convergence of artificial intelligence and biotechnology is transforming the life sciences and enabling rapid design, development, and analysis across the research lifecycle. However, this acceleration also heightens the risk for potential biological misus…
europepmc
2026
置信度 0.80
-
Although inspired by neuronal systems in the brain, artificial neural networks generally employ point-neurons, which offer computational complexity far less than that of their biological counterparts. Neurons have dendritic arbors that connect to different set…
europepmc
2025
置信度 0.80
-
Reservoir computers (RCs) are a class of recurrent neural networks that incorporate brain-inspired principles and provide an efficient alternative to deep learning. With fixed random internal connections and trained output weights, they simplify learning but r…
europepmc
2025
置信度 0.80
-
DNA computing has emerged as a transformative paradigm for tackling computational problems at the molecular level, yet existing approaches remain constrained in algorithmic interpretability, efficiency, and scalability. Here we present a DNA-based decision tre…
europepmc
2025
置信度 0.80
-
Reservoir computing (RC) exploits the intrinsic dynamics of a chaotic system, called the reservoir, to perform various time-varying functions. An important use-case of RC is the generation of temporal sequences via a trainable output-to-reservoir feedback loop…
europepmc
2025
置信度 0.80
-
MicroRNAs (miRNAs) play a significant role in biological processes, serving as potential biomarkers and therapeutic targets for disease diagnosis and treatment. However, traditional experimental methods for identifying miRNA-disease associations (MDAs) are cos…
europepmc
2025
置信度 0.80
-
Real-time wearable sleep monitors process diverse biological signals while operating under tight energy and computation budgets. The existing algorithms are facing problems of high energy consumption due to separate hardware storage and computation units. In t…
europepmc
2025
置信度 0.80
-
Spiking Neural Networks (SNNs) exhibit their optimal information-processing capability at the edge of chaos, but tuning them to this critical regime in reservoir-computing architectures usually relies on costly trial-and-error or plasticity-driven adaptation. …
europepmc
2025
置信度 0.80
-
In cardiomyocytes, the basic contractile unit are sarcomeres, which are organized in a regular manner facilitating their function. Here, we present a new computational approach to assess the functional properties of sarcomeres at the nanoscale level in human c…
europepmc
2025
置信度 0.80
-
The development of high color purity red upconversion (UC) materials operating within the second near-infrared (NIR) biological window (NIR-II) holds significant research importance for enhancing the penetration depth of such materials in biological tissues. H…
europepmc
2025
置信度 0.80
-
Purpose This study aimed to develop a Monte-Carlo (MC)-based independent dose calculation system (IDCS) for carbon-ion radiation therapy (CIRT) capable of simultaneously computing the physical dose, biological dose, and linear energy transfer (LET) distributio…
europepmc
2026
置信度 0.80
-
In building spiking neural networks for edge devices, low power consumption and time scale matching with the input signal are essential characteristics for their analog implementation. In each node of the neural network, an activation function should be implem…
europepmc
2025
置信度 0.80
-
Natural history collections are unparalleled archives of global biodiversity, yet most specimens remain molecularly uncharacterised due to the technical challenges of historical DNA (hDNA), including degradation, low endogenous content and contamination. Genom…
europepmc
2026
置信度 0.80
-
Purpose of review With an estimated 41.1B digital devices, the term "digital biomarkers" has been increasingly bandied about in the research literature. There is, however, a significant disconnect between the presumption of digital biomarkers and the reality o…
europepmc
2026
置信度 0.80
-
Biological neural networks perform complex computations to predict their environment, far exceeding the capabilities of individual neurons. Here, we argue that understanding these computations requires considering emergent dynamics-dynamics that make the whole…
europepmc
2026
置信度 0.80
-
Spiking neural (SN) P systems are computational models inspired by the functional and structural attributes of biological neurons and nervous systems. Drawing on insights from biological research, these systems incorporate intriguing mechanisms that have been …
europepmc
2025
置信度 0.80
-
Summary Microbiome HiFi Amplicon Sequence Simulator (MHASS) creates realistic synthetic PacBio HiFi amplicon sequencing datasets for microbiome studies, by integrating genome-aware abundance modeling, realistic dual-barcoding strategies, and empirically derive…
europepmc
2026
置信度 0.80
-
A phylogenetic tree has three types of attributes: size, shape (topology), and branch density. Phylodynamic studies are often motivated by questions regarding the size of clades, nevertheless, nearly all of the inference methods only make use of the other two …
europepmc
2025
置信度 0.80
-
Single memristive nanowire networks have emerged as a promising pathway for energy-efficient neuromorphic computing, owing to their intrinsic nonlinearity, high dimensionality, fading memory and volatile switching dynamics relevant to physical reservoir comput…
europepmc
2026
置信度 0.80
-
It is a challenge to endow intelligent robots with damage perception and forecast temporal data using nonvolatile memristor devices; however, volatile memristors can circumvent this issue owing to their unique ability of efficient encoding information and obli…
europepmc
2025
置信度 0.80
-
The drive toward energy-efficient, brain-inspired computing has spurred interest in ionotronic synapses that mimic ionic signaling in neurons. However, most light-driven synaptic devices overlook the influence of ion transport architecture, an essential aspect…
europepmc
2025
置信度 0.80
-
Developing a device that faithfully replicates the characteristics of biological synapses is a prerequisite for the hardware implementation of neuromorphic computing. An electronic device fabricated with metallic materials, instead of traditional semiconductor…
europepmc
2025
置信度 0.80
-
The inaugural Global Conference on Gerophysics convened 160 researchers across physics, biology, computation, and medicine in Singapore on March 5-6, 2025. With 31 speakers, the two-day event explored how physical laws, and quantitative principles unify aging …
europepmc
2026
置信度 0.80
-
Characteristics of individuals in a population, such as age and size, play a key role in determining how populations change over time. In contexts of population dynamics, identifying effective model features, such as fecundity and mortality rates, is generally…
europepmc
2025
置信度 0.80
-
europepmc
2025
置信度 0.80
-
Electrolyte solutions have a widespread presence in biological, geological, and industrial systems. To advance our understanding of these solutions, we need to develop theoretical models that can efficiently predict their collective properties. In this work, w…
europepmc
2025
置信度 0.80
-
Vancomycin-resistant enterococci (VRE) are critical nosocomial pathogens, classified as high priority by the World Health Organization (WHO) due to rising antibiotic resistance. Among these, Vancomycin-resistant Enterococcus faecium (VREfm) presents a signific…
europepmc
2025
置信度 0.80
-
Iron oxide nanoparticles (IONPs) have garnered significant attention in various fields as they exhibit interesting physical, chemical, and biological properties. This work demonstrates the green synthesis of IONPs using Averrhoa carambola leaf extract as a red…
europepmc
2025
置信度 0.80
-
Summary In the era of large data, the cloud is increasingly used as a computing environment, necessitating the development of cloud-compatible pipelines that can provide uniform analysis across disparate biological datasets. The Warp Analysis Research Pipeline…
europepmc
2025
置信度 0.80
-
Objectives We evaluated an on-premises, open-source large language model (LLM)-based data extraction pipeline for automated data extraction from unstructured electronic health records (EHRs). Methods Automated script-based EHR data preprocessing extracted 50 m…
europepmc
2026
置信度 0.80
-
The control of electron transfer pathways in transition metal complexes is crucial for developing next-generation molecular devices and photocatalysts. Herein, the electronic structure and charge delocalization mechanisms in trinuclear trans-[(NC) 5 Fe III$^{\…
europepmc
2025
置信度 0.80
-
The two-dimensional Turing machine is a promising but under used simulation tool for Artificial Life. Single-state 2-D Turing machines exhibit a variety of interesting behaviors, some of which have already been explored. Multistate 2-D Turing machines, despite…
europepmc
2025
置信度 0.80