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Yitang Zhang () emerged as a prominent mathematician in 2013 with his groundbreaking work on the Twin Prime Conjecture, proving that there are infinitely many pairs of primes with gaps less than 70 million. His paper, entitled 'Bounded Gaps Between Primes', wa…
europepmc
2025
置信度 0.80
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BackgroundThe study addresses the challenges of cognitive impairment in an aging population, focusing on the health economic assessment of technologies used by community-dwelling older adults to support cognitive function.ObjectiveTo conduct a systematic revie…
europepmc
2025
置信度 0.80
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Background During the 2019 coronavirus (COVID-19) pandemic, in-person medical visits changed due to social distancing guidelines. Breast cancer (BC) patients, needing ongoing treatment or surveillance, faced increased challenges in accessing care. Telehealth b…
europepmc
2026
置信度 0.80
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China, the world's largest generator of waste electrical and electronic equipment (WEEE), faces growing challenges in managing household WEEE and recovering embedded resources. This study develops a long-term, provincial-level assessment of household WEEE gene…
europepmc
2026
置信度 0.80
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Introduction Previous studies suggest that cognitive remediation training (CRT) programs can help address neurocognitive impairment (NCI) and associated functional challenges in multiple populations. However, no such program has been developed for persons livi…
europepmc
2026
置信度 0.80
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Brain-computer interface (BCI) presented by the non-invasive electroencephalography (EEG) cap/band or implantable chips enabling people to fast and reliable control computers or mobile devices with thoughts has redefined the boundaries of human capabilities. H…
europepmc
2026
置信度 0.80
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Changes in instrumental activities of daily living (IADL) and neuropsychiatric symptoms (NPS; e.g., apathy, depression, anxiety, and so forth) are core features of Alzheimer's disease (AD) and often precede the onset of dementia. Timely detection of these feat…
europepmc
2025
置信度 0.80
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This paper focuses on access challenges that I have experienced as someone who uses AAC, how my team and I have resolved them, and what challenges I face now. I use AAC and assistive technology (AT) to work, advocate, exercise, socialize, manage my healthcare,…
europepmc
2025
置信度 0.80
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Turing patterns are a key theoretical foundation for understanding organ development and organization. While they have been found to occur in natural systems, implementing new biological systems that form Turing patterns has remained challenging. To address th…
europepmc
2024
置信度 0.80
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Aim Geographic atrophy (GA), an advanced form of dry AMD, impacts over 5 million people globally and leads to progressive, irreversible vision loss. Current approaches to GA treatment aim to prevent and delay disease progression and preserve remaining vision. …
europepmc
2025
置信度 0.80
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The intuitive idea of self-organisation in complex dynamical systems is that global patterns and structures emerge from locally interacting elements like atoms in laser beams, molecules in chemical reactions, proteins in cells, cells in organs, neurons in brai…
europepmc
2026
置信度 0.80
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openalex
Vladimir Mironov, Thomas Boland, Thomas C. Trusk, Gabor Forgács 等
2003-04-01
置信度 0.72
Tissue engineeringRapid prototyping3D printingBiofabricationComputer science
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I argue that at least one of the following propositions is true: (1) the human species is very likely to become extinct before reaching a ‘posthuman’ stage; (2) any posthuman civilization is extremely unlikely to run a significant number of simulations of its …
openalex
Nick Bostrom
2003-04-01
置信度 0.72
PosthumanAncestorCivilizationEpistemologyGenealogy
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Computer science is the study of the phenomena surrounding computers. The founders of this society understood this very well when they called themselves the Association for Computing Machinery. The machine—not just the hardware, but the programmed, living mach…
openalex
Allen Newell, Herbert A. Simon
1976-03-01
置信度 0.72
Computer scienceOrganismHuman–computer interactionData scienceCognitive science
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How does a single-cell creature, such as an amoeba, lead such a sophisticated life? How does it hunt living prey, respond to lights, sounds, and smells, and display complex sequences of movements without the benefit of a nervous system? This book offers a star…
openalex
2009-10-01
置信度 0.72
Computer science
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Electronic computers have revolutionized virtually all aspects of our lives. However, long before these existed, cells have relied on computations implemented using biochemistry to make decisions about how to improve their chance of survival. The emerging fiel…
openalex
F. Veronica Greco, Matthew J. Tarnowski, Thomas E. Gorochowski
2019-06-01
置信度 0.72
Living systemsPerspective (graphical)ScratchComputer scienceField (mathematics)
-
In recent years, the rapid expansion in Internet access and computer-mediated communication has fostered new opportunities for individuals with health-related concerns to participate in supportive communication within a network of individuals dealing with simi…
openalex
Neil Coulson
2005-12-01
置信度 0.72
Irritable bowel syndromeSocial supportThematic analysisSupport groupPsychology
-
openalex
Francisco Varela, Humberto R. Maturana, R. Uribe
1974-05-01
置信度 0.72
AutopoiesisCharacterization (materials science)Living systemsClass (philosophy)Computer science
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The study of many biological processes requires the analysis of three-dimensional (3D) structures that change over time. Optical sectioning techniques can provide 3D data from living specimens; however, when 3D data are collected over a period of time, the qua…
openalex
C. Thomas, Peter J. DeVries, Jeff Hardin, John G. White
1996-08-02
置信度 0.72
VisualizationComputer scienceComputer graphics (images)Set (abstract data type)Data set
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OBJECTIVES: To estimate the efficacy of computer-based cognitive interventions for improving cognition in people with dementia (PWD). METHOD: Online literature databases were searched for relevant studies. Interventions were categorised as follows: cognitive r…
openalex
J. Antonio García-Casal, Andrea Loizeau, Emese Csipke, Manuel Franco 等
2016-01-25
置信度 0.72
DementiaMeta-analysisPsychological interventionPsychologyCognition
-
Natural immune systems protect animals from dangerous foreign pathogens, including bacteria, viruses, parasites, and toxins. Their role in the body is analogous to that of computer security systems in computing. Although there are many differences between livi…
openalex
Stephanie Forrest, Steven Hofmeyr, Anil Somayaji
1997-10-01
置信度 0.72
CitationLibrary scienceComputer scienceHumanitiesArt
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This study aimed to investigate the emotional impact of technology use in an Italian adult population and to detect technophobia. This cross-sectional study was conducted with 117 Italian participants (age range of 50–67 years). Measured variables were compute…
openalex
Dina Di Giacomo, Jessica Ranieri, Meny D'Amico, Federica Guerra 等
2019-09-11
置信度 0.72
AnxietyPsychologyAffect (linguistics)FeelingPopulation
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In this classic work, one of the greatest mathematicians of the twentieth century explores the analogies between computing machines and the living human brain. John von Neumann, whose many contributions to science, mathematics, and engineering include the basi…
openalex
John von Neumann
2017-12-13
置信度 0.72
Computer scienceTheme (computing)Statement (logic)Point (geometry)Set (abstract data type)
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Methods for collecting animal behaviour data in natural environments, such as direct observation and biologging, are typically limited in spatiotemporal resolution, the number of animals that can be observed and information about animals' social and physical e…
openalex
Benjamin Koger, Adwait Deshpande, Jeffrey T. Kerby, Jacob M. Graving 等
2023-03-21
置信度 0.72
Context (archaeology)DroneMovement (music)Group (periodic table)Geography
-
Using computers and the Internet to alleviate or reduce loneliness and social isolation and using online methods of data collection in the forms of online surveys and chat room interviews are in their infancy and require a descriptive qualitative study of the …
openalex
Deborah J. Clark, DEBORAH J. CLARK
2002-05-01
置信度 0.72
LonelinessThe InternetOnline chatPsychologySocial isolation
-
Judging others' personalities is an essential skill in successful social living, as personality is a key driver behind people's interactions, behaviors, and emotions. Although accurate personality judgments stem from social-cognitive skills, developments in ma…
openalex
Wu Youyou, Michał Kosiński, David Stillwell
2015-01-12
置信度 0.72
Personality psychologyPersonalitySpousePsychologyCognition
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Care of the patient at home challenges nurses with both the quantity and diversity of services required. New technologies such as computer networks may provide mechanisms to relieve the burden on traditional services, while opening new ways to meet the unique …
openalex
Patrícia Flatley Brennan, Stefan Ripich, Shirley M. Moore
1991-03-01
置信度 0.72
Intervention (counseling)MedicineDiversity (politics)NursingGerontology
-
CHESS (the Comprehensive Health Enhancement Support System) is an interactive, computer-based system to support people facing AIDS/HIV Infection and other health-related crises or concerns. CHESS provides information, referral to service providers, support in …
openalex
David H. Gustafson, Robert P. Hawkins, Eric W. Boberg, Earl Bricker 等
1994-01-01
置信度 0.72
ReferralSocial supportPopulationHealth careGerontology
-
openalex
Patricia Flatley-Brennan
1998-09-01
置信度 0.72
MedicineRandomized controlled trialGerontologyIsolation (microbiology)Social isolation
-
There has been a very rapid growth in wearable computers over the past few years. Assisted living applications leveraging wearable computers will enable a healthier lifestyle and independence in a variety of target populations, including those suffering from n…
openalex
Terrell R. Bennett, Jian Wu, Nasser Kehtarnavaz, Roozbeh Jafari
2016-03-01
置信度 0.72
Wearable computerInertial measurement unitComputer scienceIndependent livingHuman–computer interaction
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A Definition of Life. Ecosystems. Formalities. LifeThe Game. LPs. Other Worlds. Evolution. The Future. Annotated Bibliography.
openalex
Frederick B. Cohen
1994-04-27
置信度 0.72
BreedGenealogyComputer scienceHistoryBiology
-
A brain computer interface-based smart living environmental auto-adjustment control system (BSLEACS) is proposed in this paper. Recently, many environmental control systems have been proposed to improve human quality of life. However, little research has focus…
openalex
Chin‐Teng Lin, Bor‐Shyh Lin, Fu-Chang Lin, Che‐Jui Chang
2012-04-27
置信度 0.72
Universal Plug and PlayBrain–computer interfaceHome automationComputer scienceInterface (matter)
-
openalex
Michael W. Berns
1982-11-01
置信度 0.72
BiologyTracingComputer visionMotilityTracking (education)
-
openalex
Eric W. Boberg, David H. Gustafson, Robert P. Hawkins, Chien‐Lung Chan 等
1995-01-01
置信度 0.72
Subject (documents)Social supportPopulationHuman immunodeficiency virus (HIV)Psychology
-
References http://genesdev.cshlp.org/content/17/5/545.full.html#related-urls Article cited in: http://genesdev.cshlp.org/content/17/5/545.full.html#ref-list-1 This article cites 228 articles, 79 of which can be accessed free at: service Email alerting click he…
openalex
Tarik F. Massoud, Sanjiv S. Gambhir
2003-03-01
置信度 0.72
BiologyComputational biologyEvolutionary biology
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BACKGROUND: Most older adults prefer to age in place, and supporting older adults to remain in their own homes and communities is also favored by policy makers. Technology can play a role in staying independent, active and healthy. However, the use of technolo…
openalex
Sebastiaan Theodorus Michaël Peek, Katrien Luijkx, M. D. Rijnaard, Marianne Nieboer 等
2015-06-04
置信度 0.72
GerontologyAging in placeThematic analysisContext (archaeology)Nonprobability sampling
-
We use Monte Carlo simulation implementing the bond fluctuation model formalism in the canonical (NVT) ensemble to study living polymerization initiated concurrently in bulk and on flat substrates. Our results reveal that the molecular weights and molecular we…
openalex
Salomon Turgman‐Cohen, Jan Genzer
2012-02-08
置信度 0.72
DispersityPolymerPolymerizationMolar mass distributionPolymer chemistry
-
openalex
Sathiyaprakash Ramdoss, Russell Lang, Christina Fragale, Courtney Britt 等
2011-10-28
置信度 0.72
Intellectual disabilityPsychological interventionIntervention (counseling)PsychologyActivities of daily living
-
The authors design computer installations that integrate artificial life and real life by means of human-computer interaction. While exploring real-time interaction and evolutionary image processes, visitors to their interactive installations become essential …
openalex
Christa Sommerer, Laurent Mignonneau
1999-06-01
置信度 0.72
Computer scienceArtificial lifeHuman–computer interactionImage (mathematics)Personality psychology
-
This paper introduces the development of a practical brain-computer interface at Tsinghua University. The system uses frequency-coded steady-state visual evoked potentials to determine the gaze direction of the user. To ensure more universal applicability of t…
openalex
Yijun Wang, Ruiping Wang, Xiaorong Gao, Bo Hong 等
2006-06-01
置信度 0.72
Computer scienceGazeBrain–computer interfaceHuman–computer interactionInterface (matter)
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Although copious qualitative information describes the members of the diverse microbial communities on Earth, statistical approaches for quantifying and comparing the numbers and compositions of lineages in communities are lacking. We present a method that add…
openalex
Patrick D. Schloss, Jo Handelsman
2005-03-01
置信度 0.72
Species richnessOperational taxonomic unitRarefaction (ecology)BiologySampling (signal processing)
-
An adequate venous outflow is essential for securing viability of both graft and remnant in adult living donor liver transplantation (ALDLT). Seventy-five potential live liver donors were evaluated for LDLT by means of an "all-in-one" CT, which defined the bil…
openalex
A. Radtke, Silvio Nadalin, Georgios C. Sotiropoulos, Ernesto P. Molmenti 等
2006-12-05
置信度 0.72
MedicineVeinLiver transplantationVascular surgeryAbdominal surgery
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openalex
David R. Soll
1999-01-01
置信度 0.72
CrawlingPseudopodiaComputer visionMotion analysisComputer science
-
openalex
Richard J. Weinberg, Michael D. Berkus
1971-07-01
置信度 0.72
IBMComputer scienceFortranHumanitiesProgramming language
-
openalex
William Higginson, Robert K. Logan
1996-01-01
置信度 0.72
PsychologyMathematics educationLanguage acquisitionLinguisticsDevelopmental psychology
-
openalex
Katharina Kaiser, Silvia Miksch
2008-10-24
置信度 0.72
Computer scienceGuidelineProcess (computing)Task (project management)Representation (politics)
-
openalex
Noëlle Carbonell
2006-04-11
置信度 0.72
Ambient intelligenceUniversal designMultimodalityComputer scienceModalities
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Additive manufacturing (AM) alias 3D printing translates computer-aided design (CAD) virtual 3D models into physical objects. By digital slicing of CAD, 3D scan, or tomography data, AM builds objects layer by layer without the need for molds or machining. AM e…
openalex
Samuel Clark Ligon, Robert Liska, Jürgen Stampfl, Matthias Gurr 等
2017-07-30
置信度 0.72
Stereolithography3D printingNanotechnologyPolymerRapid prototyping
-
openalex
Norbert Noury, Tareq Hadidi
2012-09-13
置信度 0.72
Hidden Markov modelComputer scienceFlexibility (engineering)Home automationActivity recognition
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Overseas Filipino Workers (OFWs) and their loved ones in thePhilippines manage to have dynamic relationships despite physical distance with Computer-Mediated Communication (CMC) or the use of new media (the Internet and cellular phone). Theoretically guided by…
openalex
Almond Pilar N. Aguila
2009-12-01
置信度 0.72
Computer scienceCommunicationPsychology
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Human-centered computing is an emerging research field that aims to understand human behavior and integrate users and their social context with computer systems. One of the most recent, challenging and appealing applications in this framework consists in sensi…
openalex
Davide Anguita, Alessandro Ghio, Luca Oneto, Xavier Parra 等
2013-01-01
置信度 0.72
Activity recognitionComputer scienceContext (archaeology)Support vector machineDomain (mathematical analysis)
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BACKGROUND: In the United States, increasing numbers of persons are donating kidneys to their spouses. Despite greater histoincompatibility, the survival rates of these kidneys are higher than those of cadaveric kidneys. We examined the factors influencing the…
openalex
Paul I. Terasaki, J. Michael Cecka, David W. Gjertson, Steven K. Takemoto
1995-08-10
置信度 0.72
MedicineKidneyKidney transplantationDemographyInternal medicine
-
openalex
Matthias Weiß, Markus Elsner, Fredrik Kartberg, Tommy Nilsson
2004-08-31
置信度 0.72
Macromolecular crowdingCytoplasmCrowdingFluorescence correlation spectroscopyDiffusion
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Recently interest has grown concerning the uses of online communication for language teaching. Yet this growing interest in computer‐mediated collaborative language learning has not been matched by sufficient research and theory. This article introduces a conc…
openalex
Mark Warschauer
1997-12-01
置信度 0.72
Collaborative learningPsychologyMathematics educationComputer scienceCognitive science
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BACKGROUND: Diabetes mellitus is a significant risk factor for tuberculosis (TB). We evaluated the performance of computer-aided detection for tuberculosis (CAD4TB) in people living with diabetes mellitus (PLWD) in Indonesia. METHODS: PLWD underwent symptom sc…
openalex
Raspati Cundarani Koesoemadinata, K. Kranzer, Resvi Livia, nenden susilawati 等
2018-08-10
置信度 0.72
MedicineDiabetes mellitusReceiver operating characteristicTuberculosisTriage
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The design and implementation of new-to-nature living systems with human-defined computing capabilities is now a routine process. Cells, such as bacteria, can be rationally modified to respond to a set of inputs and deliver outputs based on algorithmic rules t…
openalex
Ángel Goñi‐Moreno
2024-04-12
置信度 0.72
TuringComputer scienceTuring machineSuper-recursive algorithmTuring machine examples
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O442 Aims: The aim of this project is computer-based planning of a partial organ resection for three dimensional visualization of anatomical structures and volumetric estimations. Introduction: Using quantitative parameters for the estimation of the operation …
openalex
M. Thor�n, Peter Schemmer, M. Schöbinger, T. Heimann 等
2004-07-01
置信度 0.72
VisualizationWorkflowSurgical planningOperation planningComputer science
-
third volume in the series on Computer Simulation of Biomolecular Systems continues with the format introduced in the first volume [1] and elaborated in the second volume [2]. primary emphasis is on the methodological aspects of simulations, although there are…
openalex
Wilfred F. van Gunsteren, Paul K. Weiner
1989-02-01
置信度 0.72
Volume (thermodynamics)Mesoscopic physicsFocus (optics)Computer scienceNanotechnology
-
openalex
Alissa N. Antle, Leslie Chesick, Srilekha Kirshnamachari Sridharan, Emily S. Cramer
2018-06-11
置信度 0.72
NeurofeedbackPovertyPsychological interventionMindfulnessIntervention (counseling)
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Computer aided three-dimensional (3-D) reconstructions of Bodo sp., a free-living kinetoplastid, were made from ultrathin (100 nm) and semithin (200 nm) serial sections, which were observed by transmission electron microscopy. Organelles and membrane systems w…
openalex
Márcia Attias, Wanderley de Souza, Rossiane C. Vommaro
1996-01-01
置信度 0.72
Contractile vacuoleVacuoleMicrotubuleGolgi apparatusBiology
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The methods for measuring the deoxyribonucleic acid content of individual mammalian cells and sorting them on the basis of this parameter have until now required fixation or other treatment which renders the cells nonviable. Using a class of bis-benzimidazole …
openalex
D. J. Arndt‐Jovin, Thomas M. Jovin
1977-07-01
置信度 0.72
DNACell sortingStainFlow cytometryBiochemistry
-
In this paper, we present an integrated system concept for the living assistance domain based on ambient intelligence technology and discuss the resulting challenges for the software engineering discipline. Automated living assistance systems represent a promi…
openalex
Jürgen Nehmer, Martin Becker, Arthur I. Karshmer, Rosemarie Santora Lamm
2006-05-28
置信度 0.72
Computer scienceAdaptabilityFlexibility (engineering)Task (project management)Domain (mathematical analysis)
-
White S and Vafopoulos M Web Science: Expanding the Notion of Computer Science, SSRN Electronic Journal, 10.2139/ssrn.1919393
openalex
Mehran Sahami, Steve Roach, Ernesto Cuadros-Vargas, Andrea Danyluk 等
2013-01-01
置信度 0.72
CurriculumDegree (music)Mathematics educationComputer scienceMedical education
-
The aim of this study was to examine in depth how computer-based assistive technology (AT) for cognitive support influenced the everyday lives of both persons who had had a stroke and their significant others. Method: Four participants, who had experienced cog…
openalex
Eva Lindqvist, Lena Borell
2011-12-08
置信度 0.72
CognitionEveryday lifeRehabilitationPsychologyActivities of daily living
-
Many children with anxiety disorders live in communities with limited access to treatment. Attention bias modification training, a promising computer-based treatment for anxiety disorders, may provide a readily accessible treatment. Recent evidence suggests th…
openalex
Allison M. Waters, Melanie J. Zimmer‐Gembeck, Michelle G. Craske, Daniel S. Pine 等
2016-06-26
置信度 0.72
AnxietyPsychologyClinical psychologyVisual searchTreatment and control groups
-
The English Longitudinal Study of Ageing (ELSA) is a panel study of a representative cohort of men and women living in England aged ≥50 years. It was designed as a sister study to the Health and Retirement Study in the USA and is multidisciplinary in orientati…
openalex
Andrew Steptoe, Elizabeth Breeze, James Banks, J. Nazroo
2012-11-09
置信度 0.72
CohortLongitudinal studyCohort studyGerontologySample (material)
-
Synthetic biology seeks to envision living cells as a matter of engineering. However, increasing evidence suggests that the genetic load imposed by the incorporation of synthetic devices in a living organism introduces a sort of unpredictability in the design …
europepmc
2016
置信度 0.80
-
Recent advances in biomolecular engineering have led to novel cancer immunotherapies with sophisticated programmed functions, including chimeric antigen receptor (CAR) T cells that bind tumor-associated antigens (TAA) to direct coordinated immune responses. Ex…
europepmc
2022
置信度 0.80
-
For decades biology has focused on decoding cellular processes one gene at a time, but many of the most pressing biological questions, as well as diseases such as cancer and heart disease, are related to complex systems involving the interaction of hundreds, o…
crossref
Markus W. Covert
2018-02-25T13:17:18Z
置信度 0.70
-
Modeling growth in bacterial cells is a major issue in systems and synthetic biology. Despite several growth rate functions proposed in the literature, most focus on nutrient composition without explicitly accounting for the possible perturbation provided by t…
arxiv
Chiara Cimolato, Elisa Gaetan, Lorenzo Pasotti, Luca Schenato 等
2026-06-12T15:35:39Z
置信度 0.78
q-bio.QM
-
One way to understand the role history plays on evolutionary trajectories is by giving ancient life a second opportunity to evolve. Our ability to empirically perform such an experiment, however, is limited by current experimental designs. Combining ancestral …
arxiv
Betul Kacar, Eric Gaucher
2012-09-23T02:15:22Z
置信度 0.78
q-bio.PEq-bio.MN
-
AI-enabled synthetic biology has tremendous potential but also significantly increases biorisks and brings about a new set of dual use concerns. The picture is complicated given the vast innovations envisioned to emerge by combining emerging technologies, as A…
arxiv
Trond Arne Undheim
2024-02-01T03:53:13Z
置信度 0.78
q-bio.OTcs.AI
-
The use of synthetic data has emerged as an essential tool in Magnetic Resonance Spectroscopy (MRS) research and applications, providing advantages for optimization of acquisition, software validation, deep learning applications, and enhanced reproducibility. …
arxiv
John T. LaMaster, Aaron T. Gudmundson, Alireza Abaei, Seyma Alcicek 等
2026-02-26T19:42:14Z
置信度 0.78
physics.med-ph
-
In sequential circuits, the current output may depend on both past and current inputs. However, certain kinds of sequential circuits do not refer to all of the past inputs to generate the current output; they only refer to a subset of past inputs. This paper i…
arxiv
Shunji Nishimura
2023-05-24T06:50:14Z
置信度 0.78
cs.OHcs.AReess.SY
-
Cellular heterogeneity is an immanent property of biological systems that covers very different aspects of life ranging from genetic diversity to cell-to-cell variability driven by stochastic molecular interactions, and noise induced cell differentiation. Here…
arxiv
Niko Komin, Alexander Skupin
2021-09-13T16:46:58Z
置信度 0.78
q-bio.QM
-
Synthetic biology aims at designing modular genetic circuits that can be assembled according to the desired function. When embedded in a cell, a circuit module becomes a small subnetwork within a larger environmental network, and its dynamics is therefore affe…
arxiv
Johannes Falk, Leo Bronstein, Maleen Hanst, Barbara Drossel 等
2018-09-25T15:39:23Z
置信度 0.78
q-bio.MNcond-mat.stat-mechphysics.bio-phphysics.chem-ph
-
DNA cloning methods are fundamental tools in molecular biology, synthetic biology, and genetic engineering that enable precise DNA manipulation for various scientific and biotechnological applications. This review systematically summarizes the major restrictio…
arxiv
Isabella Frighetto Bomfiglio, Isabelli Seiler de Medeiros Mendes, Diego Bonatto
2025-05-06T16:27:42Z
置信度 0.78
q-bio.BM
-
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. They are involved in key biological processes and then may play a major role in the development of human diseases including cancer, in particular their involveme…
arxiv
Abderrahim Chafik
2016-08-09T10:29:39Z
置信度 0.78
q-bio.MN
-
Classical molecular dynamics (MD) simulations will be able to reach sampling in the second timescale within five years, producing petabytes of simulation data at current force field accuracy. Notwithstanding this, MD will still be in the regime of low-throughp…
arxiv
Adrià Pérez, Gerard Martínez-Rosell, Gianni De Fabritiis
2018-10-19T10:39:23Z
置信度 0.78
q-bio.BMphysics.comp-ph
-
We propose a method of compiling that permits to identify quantum circuits able to simulate arbitrary $n$-qubit unitary operations via the adjustment of angles in single-qubit gates therein. The method of compiling itself extends older quantum control techniqu…
arxiv
Rahul P. Singh, A. Mandilara
2019-08-12T04:25:13Z
置信度 0.78
quant-ph
-
Genetic circuits are designed to implement certain logic in living cells, keeping burden on the host cell minimal. However, manipulating the genome often will have a significant impact for various reasons (usage of the cell machinery to express new genes, toxi…
arxiv
Aqib Hasnain, Subhrajit Sinha, Yuval Dorfan, Amin Espah Borujeni 等
2019-09-13T21:19:41Z
置信度 0.78
math.DSq-bio.QM
-
Synthetic biology is an emerging field that involves the engineering and re-design of organisms for purposes such as food security, health, and environmental protection. As such, it poses numerous ethical, legal, and social implications (ELSI) for researchers …
arxiv
Damien Dablain, Lilian Huang, Brandon Sepulvado
2022-07-10T20:18:53Z
置信度 0.78
cs.IRcs.AIcs.CY
-
Conceptual memristors have recently gathered wider interest due to their diverse application in non-von Neumann computing, machine learning, neuromorphic computing, and chaotic circuits. We introduce a compact CMOS circuit that emulates idealized memristor cha…
arxiv
Vishal Saxena
2017-11-18T06:43:25Z
置信度 0.78
cs.ET
-
The article is a short opinionated review of the quantum treatment of electromagnetic circuits, with no pretension to exhaustiveness. This review, which is an updated and modernized version of a previous set of Les Houches School lecture notes, has 3 main part…
arxiv
Uri Vool, Michel H. Devoret
2016-10-11T17:38:17Z
置信度 0.78
quant-phcond-mat.supr-con
-
I reason here that the known folk law in biology that there is no general law in biology because of exceptions is false. The (quantitative) systems biology offers the potential to solve the Borges Dilemma, by transcending it. There have already a plenty of ind…
arxiv
P Ao
2007-09-01T00:16:45Z
置信度 0.78
q-bio.QMq-bio.OT
-
The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an initial naive phenoty…
arxiv
Sean P Stromberg, Rustom Antia, Ilya Nemenman
2012-09-18T00:46:26Z
置信度 0.78
q-bio.PEq-bio.QM
-
Tropical circuits are circuits with Min and Plus, or Max and Plus operations as gates. Their importance stems from their intimate relation to dynamic programming algorithms. The power of tropical circuits lies somewhere between that of monotone boolean circuit…
arxiv
Stasys Jukna
2014-06-11T20:58:10Z
置信度 0.78
cs.CC
-
The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our understanding of living systems.…
arxiv
Ivan Ivanov, Stoyan K. Smoukov, Ehsan Nourafkan, Katharina Landfester 等
2022-07-14T23:00:09Z
置信度 0.78
q-bio.PEcond-mat.softcs.ROnlin.AOphysics.bio-ph
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Deep learning (DL) models are widely used in real-world applications but remain vulnerable to distribution shifts, especially due to weather and lighting changes. Collecting diverse real-world data for testing the robustness of DL models is resource-intensive,…
arxiv
Shashank Agnihotri, David Schader, Nico Sharei, Mehmet Ege Kaçar 等
2025-05-07T22:19:55Z
置信度 0.78
cs.CV
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This paper gives an overview of the use of control systems engineering in synthetic biology, motivated by applications such as cell therapy and cell fate reprogramming for regenerative medicine. A ubiquitous problem in these and other applications is the abili…
arxiv
Domitilla Del Vecchio
2026-01-27T23:53:33Z
置信度 0.78
eess.SYq-bio.MN
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Though it goes without saying that linear algebra is fundamental to mathematical biology, polynomial algebra is less visible. In this article, we will give a brief tour of four diverse biological problems where multivariate polynomials play a central role -- a…
arxiv
Matthew Macauley, Nora Youngs
2020-02-29T18:06:29Z
置信度 0.78
q-bio.NCq-bio.OT
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It is often stated that there are no laws in biology, where everything is contingent and could have been otherwise, being solely the result of historical accidents. Furthermore, the customary introduction of fundamental biological entities such as individual o…
arxiv
Jean-Louis Sikorav, Alan Braslau, Arach Goldar
2014-01-13T14:12:10Z
置信度 0.78
q-bio.OT
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Although reproducibility is a core tenet of the scientific method, it remains challenging to reproduce many results. Surprisingly, this also holds true for computational results in domains such as systems biology where there have been extensive standardization…
arxiv
Michael L. Blinov, John H. Gennari, Jonathan R. Karr, Ion I. Moraru 等
2021-04-09T21:09:27Z
置信度 0.78
q-bio.QMq-bio.CBq-bio.MN
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Through synthetic observations of a hydrodynamical simulation of an evolving star-forming region, we assess how the choice of observational techniques affects the measurements of properties which trace star formation. Testing and calibrating observational meas…
arxiv
Christine M. Koepferl, Thomas P. Robitaille, James E. Dale, Francesco Biscani
2016-03-07T21:00:00Z
置信度 0.78
astro-ph.SRastro-ph.GAastro-ph.IM
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There are quantum circuit identities that simplify quantum circuits, reducing the effort needed physically to implement them. This paper constructs all identities made from 3 or fewer operations taken from a common set of one qubit operations, and explains how…
arxiv
Chris Lomont
2003-07-16T13:07:40Z
置信度 0.78
quant-ph
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Within the evolving landscape of deep learning, the dilemma of data quantity and quality has been a long-standing problem. The recent advent of Large Language Models (LLMs) offers a data-centric solution to alleviate the limitations of real-world data with syn…
arxiv
Lin Long, Rui Wang, Ruixuan Xiao, Junbo Zhao 等
2024-06-14T07:47:09Z
置信度 0.78
cs.CL
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A central goal of synthetic biology is the design of molecular controllers that can manipulate the dynamics of intracellular networks in a stable and accurate manner. To address the fact that detailed knowledge about intracellular networks is unavailable, inte…
arxiv
Tomislav Plesa, Alex Dack, Thomas E. Ouldridge
2021-02-21T19:28:43Z
置信度 0.78
q-bio.MN
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I believe an atomic biology is needed to supplement present day molecular biology, if we are to design and understand proteins, as well as define, make, and use them. Topics in the paper are molecular biology and atomic biology. Electrodiffusion in the open ch…
arxiv
R. S. Eisenberg
2008-07-04T10:35:06Z
置信度 0.78
q-bio.BMphysics.bio-phq-bio.QM
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Natural biological systems process environmental information through both amplitude and frequency-modulated signals, yet engineered biological circuits have largely relied on amplitude-based regulation alone. Despite the prevalence of frequency-encoded signals…
arxiv
Rongrong Zhang, Shengjie Wan, Jiarui Xiong, Lei Ni 等
2024-11-26T07:00:48Z
置信度 0.78
physics.bio-phq-bio.MN
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Exploring generative model training for synthetic tabular data, specifically in sequential contexts such as credit card transaction data, presents significant challenges. This paper addresses these challenges, focusing on attaining both high fidelity to actual…
arxiv
Din-Yin Hsieh, Chi-Hua Wang, Guang Cheng
2024-01-01T22:34:14Z
置信度 0.78
cs.LG