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• Nondual mindfulness meditation alters self representation and brain connectome in expert meditators
  Nonduality is a foundational but conceptually elusive notion across several contemplative traditions. Nondual traditions challenge the assumption that a subject-object structure characteristic of ordinary experience is an intrinsic feature of conscious awarene…
  europepmc 2026 置信度 0.80
• Organizational principles governing synapse types in a whole-brain connectome
  Neurons are classically viewed as polarized elements in which dendrites receive synaptic input and axons provide output. However, many neurons contain intermingled presynaptic and postsynaptic sites, enabling non-canonical forms of connectivity beyond axo-dend…
  europepmc 2026 置信度 0.80
• Developmental Brain Network Trajectories Differentiate Resilience and Vulnerability to Psychosis in 22q11.2 Deletion Syndrome.
  Background Disrupted maturation of functional brain networks has been increasingly linked to elevated risk of psychosis, but the spatiotemporal characteristics of these deviations remain unclear. We used longitudinal connectome fingerprinting and jointly analy…
  europepmc 2026 置信度 0.80
• Coherent-resonant netting: disorder-enhanced selectivity from transient wave-like dynamics on biological connectomes.
  Biological agents face an energy-information bottleneck: inference requires rapid exploration of large hypothesis spaces, yet high-gain spiking is metabolically expensive. We propose Coherent-Resonant Netting (CRN) as a two-regime decision architecture in whic…
  europepmc 2026 置信度 0.80
• Shared genetic architecture between the topology of brain white matter structural connectome and fluid intelligence.
  White matter (WM) connections support efficient interregional communication and form the structural basis of human fluid intelligence. However, the shared genetic architecture between WM structural connectome and fluid intelligence remains largely unknown. In …
  europepmc 2026 置信度 0.80
• Spatiotemporal cognitive modes underlying theory of mind: A Human Connectome Project fMRI study
  Theory of mind (ToM), or mentalization, is a core aspect of social cognition that enables individuals to infer the mental states of others. Brain activity underlying ToM has been extensively studied using functional magnetic resonance imaging (fMRI), with a pr…
  europepmc 2026 置信度 0.80
• The astrocytic connectome: Gap-Junction topology beyond diffuse syncytium.
  Whether astrocytes form selective long-range networks remains unresolved. Cooper et al. use connexin 43-TurboID to reveal region-specific, plastic astrocyte gap-junction networks that partly overlap yet are not reducible to canonical neuronal projections. We d…
  europepmc 2026 置信度 0.80
• Network-Level Convergence of Adiposity-Related Gray Matter Alterations: A Coordinate-Based Connectome Mapping Meta-Analysis With Imaging Transcriptomics.
  Obesity is commonly associated with atrophy-like gray matter changes, such as lower gray matter volume or density, yet the affected regions reported vary widely across studies. It remains unclear whether these heterogeneous loci converge on a reproducible larg…
  europepmc 2026 置信度 0.80
• Local brain connectome parameters across the spectrum of clinical cognitive decline.
  Neurological disorders such as Alzheimer's disease, Parkinson's disease, and autism disrupt the brain's structural and functional organization, particularly in specific regions, and ultimately lead to cognitive impairments. In Alzheimer's disease-related demen…
  europepmc 2026 置信度 0.80
• Clinical connectomics: Mapping structural brain networks in disease.
  The human connectome holds considerable promise for advancing an integrated, systems-level understanding of brain disorders. Critical to this ambition is accurate, reliable, and biologically informative connectome mapping and analysis in the presence of divers…
  europepmc 2026 置信度 0.80
• Meta-analysis and meta-regression of diagnostic test accuracy of connectome-based predictive modeling in OCD.
  Functional magnetic resonance imaging studies have reported disruptions in functional connectivity within brain networks, known as connectomes. Researchers have tested connectomes to see whether they serve as biomarkers for various psychiatric conditions. This…
  europepmc 2026 置信度 0.80
• Cross-vendor reliability of functional and structural brain connectivity in a travelling cohort.
  Scanner-related bias is a major challenge in multi-centre neuroimaging studies. This study assesses cross-vendor reliability of functional and structural brain connectivity (FC, SC) and evaluates the effect of neuroComBat harmonisation. A travelling cohort (n …
  europepmc 2026 置信度 0.80
• Developmental patterns of the C. elegans neural circuits using community detection.
  C. elegans serves as a prime model for dissecting the developmental trajectories of nervous systems, yet, few studies have probed the functional development of its neural connectome. In this work, we utilized an enhanced version of BIGCLAM, a community detecti…
  europepmc 2026 置信度 0.80
• Functional connectome of interpersonal trust and its role in the relationship between interpersonal trust and happiness.
  Interpersonal trust (IT) is a trait-based characteristic that refers to the general tendency for someone to trust others, serving as a fundamental component of social interactions with profound implications for well-being. While prior research has consistently…
  europepmc 2026 置信度 0.80
• Biological factors contributing to divergent cortical abnormalities in adolescent and adult psychiatric disorders.
  Cortical morphological alteration patterns differ between adolescent and adult psychiatric disorders. However, the biological factors contributing to the divergence are unclear. Cortical thickness (CT) alterations in adolescents and adults with attention defic…
  europepmc 2026 置信度 0.80
• Connectome-based spatial statistics enabling large-scale population analyses of human connectome across cohorts
  Large-scale population analyses of structural connectome organization remain challenging because of cross-subject alignment, pathway interpretability and computational burden. No widely adopted standard exists for systematic evaluation across processing method…
  europepmc 2026 置信度 0.80
• Decoding Cognitive States from fMRI Using Classical Machine Learning and Temporal Dynamics Analysis: An Interpretable Approach Using the Human Connectome Project
  We propose a rigorous and reproducible methodology for analyzing functional MRI data, aimed at: (1) demonstrate their efficiency in classifying task-induced brain states with a limited amount of data, (2) present a methodology to identify brain regions critica…
  europepmc 2026 置信度 0.80
• Longitudinal structural connectome changes linked to recovery and persistence in women with postpartum depression.
  Background Clinical outcomes in postpartum depression (PPD) are highly heterogeneous, yet the neurobiological mechanisms underlying recovery remain unclear. Identifying network-based biomarkers that reflect the brain's capacity for adaptive reorganization may …
  europepmc 2026 置信度 0.80
• Altered Connectome Gradient and Its Association with Gene Expression Profiles in Patients with MELAS.
  Background and purpose Hierarchy is a fundamental principle of network organization in the human brain. Functional gradient introduces a new perspective in identifying hierarchy alterations by capturing major axes of functional connectivity in low-dimensional …
  europepmc 2026 置信度 0.80
• Structural Connectivity Selectively Constrains Intrinsic BOLD Timescales through Graph-Smooth Neural Activity
  ABSTRACT Structural connectivity defines the network architecture supporting large-scale brain dynamics, yet how this network constrains the temporal statistics of signals defined on it remains poorly understood. Prior work has reported associations between in…
  europepmc 2026 置信度 0.80
• Cortical geometry dominates structure-function coupling in resting-state fMRI: a multi-model held-out comparison on the Dallas Lifespan Brain Study
  Abstract The relationship between structural and functional brain connectivity remains a central question in network neuroscience. Two contrasting accounts have shaped the field: one emphasizes connectome topology—network motifs, communication paths, and globa…
  europepmc 2026 置信度 0.80
• Cross-sectional and longitudinal trajectories of structural connectome aging diverge: a diffusion MRI study across the adult lifespan
  Abstract Cross-sectional studies of structural-connectome organization in aging report inconsistent findings, and it is not always clear whether the inconsistency reflects pipeline differences or limits of cross-sectional design. We addressed this directly usi…
  europepmc 2026 置信度 0.80
• Theory and simulations of delayed stochastic and deterministic models of prion diseases.
  Neurodegenerative diseases (NDs), such as Alzheimer's, Parkinson's, and prion diseases, are characterized by the dynamical spread of toxic proteins through the brain. In prion diseases, cellular prion protein ( PrPC ), produced by neurons, misfolds into a toxi…
  europepmc 2026 置信度 0.80
• NeuroSparkSNT: An Eight-Operator Framework for Behavioral Phase Dynamics in C. elegans Neural Simulation
  Abstract The nematode C. elegans possesses one of the most thoroughly characterized nervous systems in biology, yet existing computational models of its locomotion occupy opposite architectural extremes: biophysi-cally detailed conductance-based simulations th…
  europepmc 2026 置信度 0.80
• Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI.
  Characterizing cortical laminar microstructure is essential for understanding the organization of the human brain. Leveraging the next-generation Connectome MRI scanner (maximum gradient strength=500mT/m, slew rate=600 T/m/s), we characterized in vivo cortical…
  europepmc 2026 置信度 0.80
• Stable depression subtypes identified using functional connectome normative deviation models and their response to rTMS.
  The heterogeneity of depression complicates treatment. Identifying stable biological subtypes could advance precision-targeted interventions. This study aims to identify stable depression subtypes using functional connectome normative deviation models and to a…
  europepmc 2026 置信度 0.80
• Connectome-guided resection of deep-seated brain tumors using tubular retractors: matched cohort outcomes and exploratory quantitative tractometry.
  OBJECTIVE: Deep-seated supratentorial tumors require surgical corridors that risk injury to eloquent white matter pathways. Tubular retractors may mitigate retraction-related injury, and patient-specific connectome mapping may further inform trajectory selecti…
  europepmc 2026 置信度 0.80
• Prediction of Q-CHAT scores based on Functional Connectivity in Healthy Newborns
  Neonatal resting-state functional connectivity may provide early markers of later variation in Q-CHAT scores, measured dimensionally within a non-clinical population, but the large-scale systems carrying the most robust predictive signal remain unclear. Using …
  europepmc 2026 置信度 0.80
• Testing the Hypothesis of Habenula Hyperactivity in Depression: A Study Using Fractional Amplitude of Low-Frequency Fluctuation (fALFF)
  Background: The habenula, a key regulator of aversive processing, has been consistently implicated in animal models of depression, where elevated baseline activity is a robust and reproducible finding. This has led to the widely discussed hypothesis that haben…
  europepmc 2026 置信度 0.80
• Reproducibility and model-selection stability in connectome-constrained circuit modeling
  Connectome-constrained neural network models aim to link anatomical connectivity with functional computation by training networks whose architectures reflect biological circuits. Because such models are increasingly used to infer neural mechanisms, it is impor…
  europepmc 2026 置信度 0.80
• Functional Synaptic Interactions and Inhibitory Circuitry of the PreBötzinger Complex in the Rhythmic Slice.
  The pre-Bötzinger complex (preBötC) within the medulla oblongata contains neuronal circuits critical for generating the mammalian respiratory rhythm, but the functional connectivity among its core excitatory and inhibitory populations remains debated. Defining…
  europepmc 2026 置信度 0.80
• Hierarchical Network Adaptations and Structure-Function Scaffolding in the Deaf Adult Brain.
  Cortical networks reorganize following early sensory deprivation, yet the relationship between structural architecture and large-scale functional organization remains incompletely understood. We examined connectome organization in 54 congenitally deaf adults a…
  europepmc 2026 置信度 0.80
• Treatment-related topological reorganization of the structural connectome in major depressive disorder with suicidal ideation.
  Background Major depressive disorder with suicidal ideation (MDD-SI) is associated with a high risk of mortality. The specific longitudinal alterations in brain structural networks associated with SI remain unclear. We aimed to identify treatment-related topol…
  europepmc 2026 置信度 0.80
• Convergent resting-state functional connectivity and meta-analytic functional decoding for describing probabilistic maps of visual perception of emotional constructs.
  Understanding how distributed visual subsystems are integrated within the brain's large-scale architecture is essential for characterizing visual perception and its interaction with cognitive and affective processes. Using probabilistic visual topographic maps…
  europepmc 2026 置信度 0.80
• A Human Gait Circuit Derived from Brain Lesions and Deep Brain Stimulation.
  The human neuroanatomy for gait dysfunction remains unclear. We sought (1) to identify a brain circuit for gait impairment post stroke, (2) to identify a brain circuit for gait changes after subthalamic deep brain stimulation (DBS) for Parkinson's disease (PD)…
  pubmed Luo L, Schaper FLWVJ, Nguyen M, Garimella AH 等 2026 Aug 6 置信度 0.82
• Hippocampal CA3 connectomics reveals a gradient of mossy fiber inputs and selective feedforward inhibition onto pyramidal cells.
  The mossy fiber (MF) connections to pyramidal cells in hippocampal CA3 are thought to participate in pattern separation, pattern completion and memory encoding, yet no large-scale neuronal wiring diagram exists for these connections. We assembled a 3D electron…
  pubmed Zheng Z, Park C, Hammerschmith EW, Lu R 等 2026 Aug 5 置信度 0.82
• Construction and clinical validation of a cascaded deep learning system for classification of benign and malignant solid small renal masses based on MRI.
  This study aims to develop a cascaded deep learning (DL) system based on multiparametric MRI to establish an automated pipeline for the segmentation and classification of small renal masses (SRMs).
  pubmed Cui M, Zeng Z, Chen S, Jin Y 等 2026 Jul 31 置信度 0.82
• Caenorhabditis elegans in neuroscience: from neural communication to neurodegenerative disease modeling.
  Consistent with humans and other metazoans, the nematode Caenorhabditis elegans ( C. elegans ) undergoes progressive structural and functional decline during aging. Possessing highly conserved genetic pathways that share extensive homology with human genes, an…
  pubmed Pan Z, Shen Y, Peng D, Tang L 等 2026 置信度 0.82
• Tunneling nanotubes in the nervous system: The fourth pillar of brain connectivity.
  Tunneling nanotubes (TNTs) are thin, actin-based membranous conduits that enable direct and indirect cytoplasmic exchange between distant cells. Once considered a rare in vitro phenomenon, TNTs are increasingly recognized as dynamic intercellular communication…
  pubmed Budinger D, Heneka MT 2026 Aug 3 置信度 0.82
• Multi-delay arterial spin labelling-based metabolic connectomes reveals topological alterations in Parkinson's disease.
  Parkinson's disease (PD) is characterized by widespread brain network dysfunction. Although metabolic abnormalities have been reported, network-level alterations in metabolic connectomes remain insufficiently understood.
  pubmed Thakur M, Ding S, Lu X, Chen B 等 2026 Aug 1 置信度 0.82
• Opposing associations of default mode network and subcortical network efficiency with IQ in children with drug-resistant epilepsy.
  Paediatric drug-resistant epilepsy (DRE) is associated with IQ deficits only partially explained by clinical seizure variables (for example, age of onset, seizure burden, seizure location). Given that intelligence depends on efficient large-scale brain network…
  pubmed Tawde P, Velanoski D, Piper RJ, Stark D 等 2026 Aug 1 置信度 0.82
• Diffusion Tensor Imaging Metrics Reveal Pronounced Hemispheric Asymmetry in Major White Matter Tracts.
  AIM: To determine hemispheric asymmetries in major white matter tracts using diffusion tensor imaging (DTI) metrics and morphometric measurements, as comprehensive multitract analyses remain limited. MATERIAL and METHODS: Diffusion MRI data from 102 healthy ad…
  pubmed Khaniyev T, Cekic E, Altug MY, Gok E 等 2026 置信度 0.82
• Neural manifold connectomics reveals multiregime functional connectivity.
  Neural activity is organized in low-dimensional structure, yet functional connectivity in fMRI typically represents each brain parcel by a single voxel-averaged time series. This scalar representation makes whole-brain connectivity tractable but discards poten…
  pubmed Velidi P, Amico E, Nathoo F, Miranda MF 2026 Jul 26 置信度 0.82
• Spectral organization of individualized connectome harmonics across brain structure, function and cognition.
  Connectome harmonics provide a spectral representation of structural brain connectivity that has emerged as a powerful framework for studying structure-function relationships. However, two fundamental questions remain unresolved: how should inter-individual va…
  pubmed Bolton TAW, Sieler MS, Patel J, Chan M 等 2026 Jul 20 置信度 0.82
• TractEdit: An open-source interactive tool for virtual dissection and manual refinement of diffusion MRI tractography.
  Accurate reconstruction of white matter pathways is essential for connectomics and pre-surgical planning. However, tractography algorithms inherently generate false positives, necessitating manual refinement ("virtual dissection") to isolate specific bundles a…
  pubmed Tagliaferri M, Cattaneo L 2026 Jul 31 置信度 0.82
• Functional Synaptic Interactions and Inhibitory Circuitry of the PreBötzinger Complex in the Rhythmic Slice.
  The preBötzinger Complex (preBötC) within the medulla oblongata contains neuronal circuits critical for generating the mammalian respiratory rhythm, but the functional connectivity among its core excitatory and inhibitory populations remains debated.…
  pubmed Molkov YI, Koizumi H, Smith JC 2026 Jul 31 置信度 0.82
• Anatomical modeling of visceral afferent innervation in the rodent stomach.
  Understanding the sensory nervous system's precise innervation of visceral organs remains a major challenge in systems neuroscience, particularly for designing neuromodulatory therapies. Here, we introduce a digital twin of the rodent stomach that combines hig…
  pubmed Nguyen D, Lin MY, Ma J, Kwiat AM 等 2026 Jul 21 置信度 0.82
• A longitudinal resource for mapping interindividual variation in the aging connectome.
  Trajectories of age-related neurocognitive decline are nonuniform, and are impacted by numerous environmental and physiological factors. Earlier life phases set the stage for later life neurocognitive function, with midlife marking a critical transition charac…
  pubmed MacKay-Brandt A, Gazes Y, Garcia-Barnett D, Grebe LA 等 2026 Jul 30 置信度 0.82
• Resting-state EEG connectome topology and social norm processing in healthy young adults.
  Resting-state network topology may provide a powerful framework for understanding how large-scale brain organisation supports cognitive functions. However, the topological correlates of social cognition remain poorly characterised. This study examined whether …
  pubmed Cavallo ND, Papallo S, Chianese M, Donisi L 等 2026 Jul 30 置信度 0.82
• Robust probabilistic measurement of structural-functional module consistency in infant brain development.
  Brain network is commonly divided into modules for analyzing their functionally segregated roles for group-level analysis in neuroimaging studies. Here, we introduce stochastic modules within brain networks for a robust probabilistic measurement of structural-…
  pubmed Bian L, Liu F, Wang Q, Zhang H 等 2026 Jul 30 置信度 0.82
• The turbulent brain: Modeling vortex interactions for understanding human cognition.
  The human brain needs distributed, time-critical computation to efficiently solve complex problems. Turbulence provides such highly efficient spacetime information processing and transmission across widespread brain networks, yet we have been missing a mechani…
  pubmed Deco G, Sanz Perl Y, Feng J, Kringelbach ML 2026 置信度 0.82
• NeuroMArVL: An interactive and collaborative web-based tool for visualizing brain networks.
  Brain connectivity data are high-dimensional and are often modeled as graphs comprising in the order of ∼10 2 -10 4 nodes connected by around 10 3 -10 6 edges. Generating useful visualizations is essential for reducing and understanding such complexity.…
  pubmed Adamson CL, Gajwani M, Klapperstueck M, Manley J 等 2026 置信度 0.82
• Experimental quality control induces changes in Allen mouse brain connectomes.
  The Allen Mouse Brain Connectivity Atlas (AMBCA) is widely used to represent structural connectivity in the mouse brain. The AMBCA consists of tracer injection experiments where neuronal projections axonally connected to the initial injection site are labeled.…
  pubmed Nathan V, Tullo S, Herrera-Portillo L, Devenyi GA 等 2026 置信度 0.82
• Effect of database, pre-processing pipeline, and scan duration on rs-fMRI functional connectivity based treatment targets for TMS obtained using the Stanford Neuromodulation Therapy (SNT) protocol.
  Transcranial Magnetic Stimulation targeting the dorsolateral prefrontal cortex (DLPFC) is a therapeutic approach for treating depressive disorder. However, traditional anatomical methods often fail to localize a treatment target. The functional connectivity me…
  pubmed Yu L, Li X, Roberts N, Huang X 等 2026 置信度 0.82
• Disrupted hierarchical functional brain organization in affective and psychotic disorders: insights from functional brain gradients.
  Individuals with psychosis and depression show widespread alterations in brain resting-state functional connectivity (rs-FC), affecting both sensory and higher-order brain regions. In this study, we investigate disruptions in the hierarchical organization of b…
  pubmed Hacker H, Hoheisel L, Buciuman MO, Böke A 等 2026 Jul 29 置信度 0.82
• Pre-Training for Large-Scale Functional Connectome Fingerprinting Supports Generalization and Transfer Learning in Functional Neuroimaging.
  Functional MRI currently supports a limited application space stemming from modest dataset sizes, large interindividual variability and heterogeneity among scanning protocols. These constraints have made it difficult for fMRI researchers to take full advantage…
  pubmed Ogg M, Kitchell L 2026 Jul 29 置信度 0.82
• Connectome-guided personalization of optimal tDCS intervention selection in Alzheimer's disease: A modeling study.
  Transcranial direct current stimulation (tDCS) could reduce the neurophysiological effects in Alzheimer's disease (AD), but progress is hampered by variable outcomes across studies, likely related to both methodological and individual differences. We recently …
  pubmed Luppi JJ, Koomen AP, Stam CJ, Scheltens P 等 2026 Jul 29 置信度 0.82
• Cortical Hub Vulnerability and Molecular Signatures of Sulcal Widening in Schizophrenia.
  Schizophrenia is increasingly conceptualized as a disorder of large-scale brain network organization arising from atypical neurodevelopment. However, the relationship between early-emerging cortical folding patterns and the maturation of the structural connect…
  pubmed González-Peñas J, Schnack HG, Hernández CR, Díaz-Caneja CM 等 2026 Jul 29 置信度 0.82
• Multi-Frequency EEG Connectomics Uncovers Insula-Network Subtypes in Somatic Symptom Disorder.
  Somatic symptom disorder (SSD) exhibits substantial clinical heterogeneity that limits treatment efficacy, with over 40% of patients failing to respond to standard interventions. Here, we developed a framework that integrates multi-frequency electroencephalogr…
  pubmed Zhao S, Lian C, Shi X, Dang G 等 2026 Jul 29 置信度 0.82
• Cortical and network architectures in limb and oral apraxia.
  To characterize the distinct network principles underlying limb and oral apraxias, we investigated the structural brain lesions and white matter disconnections associated with limb apraxia (LA), buccofacial apraxia (BFA), and apraxia of speech (AOS) within a s…
  pubmed Nishio Y, Itabashi R, Kataoka Y, Yazawa Y 等 2026 Jul 20 置信度 0.82
• Subthalamic spatio-spectral-connectivity of psychiatric symptoms in Parkinson's disease.
  Psychiatric symptoms in Parkinson's disease (PD) are highly prevalent and challenging to treat. This study maps oscillatory neural activity to diverse psychiatric symptoms in PD, using resting-state subthalamic nucleus (STN) local field potentials (LFPs) and f…
  pubmed Wang L, Zhao Y, Huang P, Ding Q 等 2026 Jul 29 置信度 0.82
• Functional connectivity gradients depend on cortical sampling position and brain state.
  Functional-connectivity analyses often treat signals sampled from nearby cortical positions as interchangeable, despite anatomical and hemodynamic transitions at the gray-white boundary. We tested whether sampling position constitutes a state-sensitive dimensi…
  pubmed Li M, Ding Z, Gore JC 2026 Jul 18 置信度 0.82
• Selective convergence and graded divergence of hippocampal and amygdala subregions using functional connectivity.
  The hippocampus and amygdala are neighboring medial temporal lobe structures linked to memory and affect, yet how their subregions are jointly embedded within distributed isocortical systems remains unclear. Using resting-state fMRI from 722 Human Connectome P…
  pubmed Erigüç DY, Marsiglia M, John A, Bayrak Ş 等 2026 Jul 18 置信度 0.82
• White-Matter BOLD Encoding Beyond Marginal Connectivity.
  Functional MRI studies have traditionally focused on gray matter, whereas white-matter BOLD signals have often been treated as weak or artifactual. Recent work suggests that white-matter BOLD fluctuations contain reproducible functional information, but most g…
  pubmed Li M, Ding Z, Gore JC 2026 Jul 13 置信度 0.82
• From behavioral profiles to neural scaffolds: cortico-striatal integrity predicts longitudinal stability and transition in psychological adaptability during early adulthood.
  Psychological adaptability hinges on the dynamic balance between cognitive regulation (self-control) and emotional reactivity (impulsivity, reward/punishment sensitivity). However, traditional variable-centered approaches often fail to capture how these traits…
  pubmed He J, Zhao H, Lei X, Qiu J 等 2026 Jul 29 置信度 0.82
• White matter functional connectome topology and its clinical correlations in adolescent major depressive disorder.
  Adolescence is a critical period for brain network remodeling and the onset of major depressive disorder (MDD); however, white matter (WM) functional topology in adolescent MDD remains underexplored. Given that WM functional signals reflect meaningful neural a…
  pubmed Chen K, Li X, Chen H, He Y 等 2026 置信度 0.82
• From Sensorimotor to Transmodal Cortex: Sleep Quality Aligns Brain Entropy with the Cortical Functional Gradient.
  Sleep is fundamental to brain health, yet the mechanisms by which habitual sleep quality shapes large-scale neural dynamics during wakefulness remain unclear. This work aims at determining whether habitual sleep quality is associated with systematic alteration…
  pubmed Del Mauro G, Li Y, Yu J, Wickwire E 等 2026 Jul 28 置信度 0.82
• Whole-Brain Structural Connectivity Alterations in Chronic Subjective Tinnitus: An Exploratory Diffusion Tensor Imaging Study.
  Background/Objectives: Subjective tinnitus, the underlying mechanism of which remains largely unknown, accounts for the majority of cases. Although conventional MRI and audiometric assessments demonstrate limited effectiveness in identifying organic causes, ad…
  pubmed Elpen Karyemez P, Ulus S, Yılmaz E, Yıldırım D 2026 Jul 12 置信度 0.82
• Functional Connectome Predicts Cognition and Links White Matter Hyperintensity Burden to Cognitive Impairment Across the Vascular Cognitive Impairment Continuum.
  Background : White matter hyperintensity (WMH) is a hallmark of cerebral small vessel disease and an important contributor to vascular cognitive impairment (VCI), yet lesion burden incompletely explains interindividual variability in cognitive outcomes across …
  pubmed He H, Fang Y, Jiang J, Lu D 等 2026 Jun 30 置信度 0.82
• Identification of structural disconnection subnetworks in acute and subacute post-stroke depression.
  Post-stroke depression (PSD) is common after acute ischemic stroke, yet its neural substrates remain unclear. This study identified structural disconnection subnetworks associated with PSD and evaluated their association with depression severity and topology.
  pubmed Liang W, Fang Y, Li T, Du Q 等 2026 Jul 27 置信度 0.82
• Developmental Brain Network Trajectories Differentiate Resilience and Vulnerability to Psychosis in 22q11.2 Deletion Syndrome.
  Disrupted maturation of functional brain networks has been increasingly linked to elevated risk of psychosis, but the spatiotemporal characteristics of these deviations remain unclear. We used longitudinal connectome fingerprinting and jointly analyzed the fun…
  pubmed Forrer S, Delavari F, Sandini C, Van De Ville D 等 2026 Sep 置信度 0.82
• Brain network alterations in autoimmune diseases: Current status and future prospects.
  Autoimmune diseases are frequently associated with neurological and cognitive dysfunction. Advances in neuroimaging and graph theory-based connectomics have enabled investigation of large-scale brain network alterations across autoimmune conditions. This revie…
  pubmed Lee XN, Zhang H, Zhou H 2026 Aug 21 置信度 0.82
• Multivariate environmental exposures are reflected in whole-brain functional connectivity and cognition in youth.
  Each individual's complex, multidimensional environment, known as their "exposome", plays an essential role in shaping cognitive neurodevelopment. Understanding the mechanisms whereby children's exposome influences their development is crucial to facilitate th…
  pubmed Lichenstein SD, Weng Y, Robinson H, Rodriguez L 等 2026 Jul 22 置信度 0.82
• Deep Brain Stimulation for Disorders of Consciousness: From Mesocircuit Mechanisms to Circuit-Guided Precision Neuromodulation.
  Disorders of consciousness (DoC) following severe brain injury represent a formidable clinical challenge, with limited therapeutic options for patients in prolonged unresponsive or minimally conscious states. Deep brain stimulation (DBS) of the central thalamu…
  pubmed Zang D, Hasuike K, Qi Z, Yu Y 等 2026 Jul 25 置信度 0.82
• The Anatomical Connections of Nucleus Accumbens with Brainstem and Cerebellum in the Rat and Human Subjects.
  The nucleus accumbens (NAc) plays a key role in reward-related behaviors and is involved in several neurological and psychiatric disorders. While the cortical and subcortical connections of the NAc are well-documented, its anatomical connectivity with brainste…
  pubmed Çavdar S, Altınöz D, Özkan M, Erkan E 等 2026 Jul 25 置信度 0.82
• Reply to: Patient-Reported Feedback in Essential Tremor Deep Brain Stimulation: Distinguishing Perceived Comfort from Tremor Suppression.
  pubmed Peschke S, Dong J, Kirschner A, Off J 等 2026 Jul 25 置信度 0.82
• Connectome-based mapping of gray matter abnormalities in hepatic encephalopathy.
  Hepatic encephalopathy (HE) is linked to widespread gray matter abnormalities, but it remains unclear whether these changes follow the organizing principles of large-scale brain networks. This study examined the spatial distribution of gray matter abnormalitie…
  pubmed Chen L, Xia L, Chen Y, Hong C 等 2026 置信度 0.82
• Alterations in resting-state control energy of limbic-to-subcortical networks in individuals with alcohol use disorder and comorbid sleep disturbances.
  Alcohol use disorder (AUD) is frequently comorbid with sleep disturbances, yet the neural mechanisms through which sleep and AUD jointly shape brain organization remain unclear. Conventional resting-state analyses describe connectivity but not the energetic co…
  pubmed Zeng N, Ding M, Wang M, Hu Q 2026 Jul 23 置信度 0.82
• Altered Cortical Morphological Brain Networks and Their Diagnostic Classification Utility in Major Depressive Disorder.
  Major depressive disorder (MDD) has been increasingly characterized as a network dysconnectivity syndrome. Although single-subject morphological networks are advantageous in studying the brain connectome, extant research on MDD is limited by either small sampl…
  pubmed Sun X, Shen Y, Chen X, Lu B 等 2026 Aug 1 置信度 0.82
• Single-neuron connectome of the central amygdala in the mouse brain.
  The central amygdala (CeA) orchestrates defensive behaviors, pain processing, and stress responses, yet how its molecularly defined neuronal subtypes are embedded in brain-wide circuits remains unclear. Here, we reconstructed the brain-wide input and output ar…
  pubmed Wang LH, Song W, Chen X, Li Q 等 2026 Jul 23 置信度 0.82
• Multiplex gray and white matter networks in autism spectrum disorder: differential topological alterations and transcriptomic associations.
  Autism spectrum disorder (ASD) is classically conceptualized as a dysconnectivity syndrome. However, most studies have examined structural and functional connectivity in isolation, leaving the coupling mechanisms between brain structure and function, particula…
  pubmed Wan Y, Xiao H, Chen H, Zhang X 等 2026 Jul 23 置信度 0.82
• Associations between neuronavigated rTMS-mediated functional connectome plasticity and neurotransmitter receptors in Alzheimer's disease.
  Cognitive improvement is mediated by repetitive transcranial magnetic stimulation (rTMS) in Alzheimer's disease (AD), and connectome gradient analysis has important potential to explore more comprehensive information for treatment efficacy. However, it remains…
  pubmed Yao W, Lv T, Zheng W, Liu Y 等 2026 Jul-Sep 置信度 0.82
• Formic Acid Enhanced Single-Pot Sample Preparation to Improve Identification Coverage of Membrane Proteome of Laser Capture Microdissected Tissue Sections.
  To interpret the heterogeneous multicellular microenvironment in biological tissues, cell type-resolved global proteome profiling has attracted great attention. Due to its high compatibility with mass spectrometry (MS), n-Dodecyl-d-maltoside (DDM) is commonly …
  pubmed He Y, He X, Liu D, Xie Y 等 2026 Aug 4 置信度 0.82
• Advancing spine connectomics and neural integration through machine learning and neuroengineering: a narrative review.
  Spinal connectomics is increasingly shifting understanding of the spinal cord from a simple reflex relay toward an active system that contributes to sensorimotor integration and adaptive motor control. This narrative review summarizes recent advances in the st…
  pubmed Kumar R, Kaur H, Sporn K, Salman SG 等 2026 Jul 23 置信度 0.82
• DDSurfer: A Weakly-Supervised Dual-Stream Deep Learning Framework for Cortical Surface Reconstruction From Diffusion MRI.
  Cortical surface reconstruction of white matter and pial surfaces from diffusion MRI (dMRI) is critical for neuroimaging analyses, including tractography, connectomics, and multimodal data integration. However, obtaining these surfaces from dMRI data is inhere…
  pubmed Li C, Zhang W, Zhu X, Chen Y 等 2026 Jul 23 置信度 0.82
• A Multiscale Spatiotemporal Causal Mapping Algorithm for Revealing Neural Network Mechanisms of Transcutaneous Auricular Vagus Nerve Stimulation.
  Transcutaneous auricular vagus nerve stimulation (taVNS) has shown promise in enhancing cognitive and emotional functions, yet its neural mechanisms remain unclear largely because existing analytical methods cannot characterize multiscale functional connectivi…
  pubmed Wang W, Wang R, Lin P, Leng Y 等 2026 Aug 置信度 0.82
• A global molecular code for birth order and neuronal identity in Drosophila.
  The assembly of functional neural circuits relies on the generation of diverse neural types with precise molecular identity and connectivity. Unlocking general principles of neuronal specification and wiring across the nervous system requires a systematic and …
  pubmed Cachero S, Mitletton M, Beckett IR, Marin EC 等 2026 Jul 22 置信度 0.82
• Personalized metabolic connectome analysis reveals glucose heterogeneity in ischemic cerebrovascular disease.
  This study aimed to establish individualized metabolic networks for patients with ischemic cerebrovascular disease (ICVD) using cerebral glucose metabolism data and to analyze topological alterations before and after surgical intervention.
  pubmed Cui B, Zhang Q, Shan Y, Wei X 等 2026 Jul 22 置信度 0.82
• Functional connectome signature of general psychopathology in middle-aged and older adults: Evidence from multi-cohort, multi-ethnic analyses.
  Mental health disorders are increasingly prevalent in middle-aged and older adults, a population undergoing substantial brain network reorganization. We aimed to identify whole-brain connectivity patterns associated with transdiagnostic psychiatric dimensions …
  pubmed Nguyen TT, Ng KK, Lew VH, Koi JJX 等 2026 置信度 0.82
• EXPRESS: Somatotopic Homunculus Profiles of Motor Cortex and Corticospinal Tract in Aging.
  Motor performance declines with aging, yet how somatotopic subregions of the primary motor cortex (M1) and corticospinal tract (CST) show region-specific structural and functional changes during aging remains unclear.
  pubmed Wen J, Li C, Jiang L, Pang H 等 2026 Jul 21 置信度 0.82
• Performance of detector modules designed for the NeuroSphere brain PET system.
  The Human Dynamic NeuroChemical Connectome (HDNCC) scanner integrates a high spatio-temporal resolution dedicated brain PET insert (NeuroSphere PET) with a commercial 7-T MRI to enable studies of neurochemical dynamics simultaneously with functional MRI on com…
  pubmed Allen MS, Byars L, Rauscher L, Scipioni M 等 2026 Aug 置信度 0.82
• Brain network dynamics reflect psychiatric illness status and transdiagnostic symptom profiles across health and disease.
  The network organization of the human brain dynamically reconfigures in response to changing environmental demands, an adaptive process that may be disrupted in a symptom-relevant manner across psychiatric illnesses. Here, in a transdiagnostic sample of partic…
  pubmed Cocuzza CV, Chopra S, Segal A, Labache L 等 2026 Jul 21 置信度 0.82
• Cortical and Subcortical Stimulation for Pain: Network Mechanisms and Therapeutic Implications.
  Chronic pain affects up to one-third of adults worldwide and remains refractory to conventional therapies in a substantial proportion of patients. Increasing evidence suggests that chronic pain arises from maladaptive interactions across distributed peripheral…
  pubmed Rudd G, Di Ieva A 2026 Jul 21 置信度 0.82
• Afferent and efferent projections of parvalbumin-expressing neurons in the thalamic reticular nucleus of the mouse.
  The whole-brain connectivity of thalamic reticular nucleus (TRN) parvalbumin-positive (PV + ) neurons has been characterized at the population level, yet their single-cell projectome diversity and the corresponding electrophysiological heterogeneity remain inc…
  pubmed Li YY, Qiu XT, Ren X, Wang HJ 等 2026 Jul 21 置信度 0.82
• Bilateral Neuron Pairs Share Redundant Network Roles Despite Incomplete Connection Symmetry in Caenorhabditis elegans.
  Bilateral organization is a prominent feature of the C. elegans nervous system, yet bilateral neuron pairs differ substantially in their individual left-right connections. Whether, and how, such pairs nonetheless come to occupy similar roles in the network is …
  pubmed Kim PS, Song Y, Kralik JD, Jeong J 2026 Jul 置信度 0.82
• Diffusion neuroimaging of speech acquisition in infants.
  How multisystem white-matter maturation supports early speech acquisition in infancy remains unclear. Using longitudinal diffusion MRI from the Baby Connectome Project, we quantified neurite density maturation from birth to 24 months across 33 white-matter tra…
  pubmed Liu F, Liu J, Gu J, Wang Y 等 2026 Jul 20 置信度 0.82
• Success and Failure With the Antidyskinetic Effect of Globus Pallidus Internus Deep Brain Stimulation: A Sweet Spot and Connectivity Analysis in the CSP-468 Cohort.
  Deep brain stimulation (DBS) of the globus pallidus internus (GPi) can reduce levodopa-induced dyskinesias, yet GPi targeting sometimes fails or worsens them, suggesting distinct prokinetic/antikinetic circuit mechanisms. Using the broad globus pallidus (GP) s…
  pubmed D'Souza S, Shah HP, Seshadri V, Toms J 等 2026 Jun 23 置信度 0.82
• Organization of circuits linking descending input to motor output in the Drosophila Male Adult Nerve Cord connectome.
  In most animals, a small number of descending neurons (DNs) connect the brain to circuits and motor neurons (MNs) in the nerve cord. To understand how brain signals generate behavior, it is critical to understand the organization of the neural pathways linking…
  pubmed Cheong HSJ, Eichler K, Stürner T, Asinof SK 等 2026 Jul 20 置信度 0.82
• Exploring the mediating role of functional connectivity in the association between violence exposure and psychopathology during early adolescence.
  Early adolescence represents a sensitive developmental period characterized by rapid maturation of large scale brain systems and heightened vulnerability to environmental influences, such as exposure to violence. Guided by the Triple Network Model of Psychopat…
  pubmed Jagasia E, Nebel MB, Johnson S, Campbell J 等 2026 Aug 置信度 0.82
• Resting-state functional connectivity alterations in adult ADHD: A systematic review of rs-fMRI studies.
  Attention-Deficit/Hyperactivity Disorder (ADHD) often persists into adulthood and causes significant functional impairments. Resting-state functional MRI (rs-fMRI) offers valuable insights into intrinsic brain connectivity; however, connectivity (FC) alteratio…
  pubmed Kakadiya J, de Macedo BA, Vora N, Dhaduk V 等 2026 Oct 置信度 0.82