脑科学 · 全部实体（第 77 / 100 页）

本页收录第 7601–7700 条，共 10000 条 · 返回 脑科学 首页

• The neuroscience of human relationships: attachment and the developing social brain
  Since the publication of the first edition in 2006, the field of social neuroscience has grown at a mind-numbing pace. Technical advances now provide more windows into our inner neural universe and terms like attachment, empathy, compassion, and mindfulness ha…
  openalex Louis Cozolino 2014-07-16 置信度 0.72 Social neuroscienceCognitive sciencePsychologyNeuroscienceHuman brain
• Neuroscience and education
  Neuroscience is a relatively new discipline encompassing neurology, psychology and biology. It has made great strides in the last 100 years, during which many aspects of the physiology, biochemistry, pharmacology and structure of the vertebrate brain have been…
  openalex Usha Goswami 2004-03-01 置信度 0.72 Cognitive scienceCognitionPsychologyEducational neuroscienceNeuroimaging
• Frontiers in Aging Neuroscience
  openalex 2018-11-05 置信度 0.72 NeuroscienceComputational neurosciencePsychologyNeuroscientistCognitive science
• The new visual neurosciences
  Visual science is the model system for neuroscience, its findings relevant to all other areas. This essential reference to contemporary visual neuroscience covers the extraordinary range of the field today, from molecules and cell assemblies to systems and the…
  openalex John S. Werner, Leo M. Chalupa, Marie E. Burns 2014-01-01 置信度 0.72 Cognitive scienceNeuroscienceVisual perceptionVision sciencePsychology
• The neurosciences-third study program
  openalex H. Hécaen 1975-10-01 置信度 0.72 PsychologyCognitive scienceCognitive psychologyNeuroscience
• Toward Systems Neuroscience of ADHD: A Meta-Analysis of 55 fMRI Studies
  OBJECTIVE: The authors performed a comprehensive meta-analysis of task-based functional MRI studies of attention deficit hyperactivity disorder (ADHD). METHOD: The authors searched PubMed, Ovid, EMBASE, Web of Science, ERIC, CINAHAL, and NeuroSynth for studies…
  openalex Samuele Cortese, Clare Kelly, Camille Chabernaud, Erika Proal 等 2012-10-01 置信度 0.72 NeurosciencePsychologyNeuroimagingMeta-analysisCognitive science
• The neuroscience of prejudice and stereotyping
  openalex David M. Amodio 2014-09-04 置信度 0.72 Prejudice (legal term)PsychologySocial neuroscienceSocial psychologyDiversity (politics)
• Virtual Reality for Enhanced Ecological Validity and Experimental Control in the Clinical, Affective and Social Neurosciences
  An essential tension can be found between researchers interested in ecological validity and those concerned with maintaining experimental control. Research in the human neurosciences often involves the use of simple and static stimuli lacking many of the poten…
  openalex Thomas D. Parsons 2015-12-11 置信度 0.72 Ecological validityVirtual realityPsychologyControl (management)Cognitive psychology
• Computational Neuroscience of Vision
  Abstract This book presents the highly complex subject of vision, focusing on the visual information processing and computational operations in the visual system that lead to representations of objects in the brain. In addition to visual processing, it also co…
  openalex Edmund T. Rolls, Gustavo Deco 2001-11-01 置信度 0.72 Computational neuroscienceComputer scienceVision for perception and vision for actionVisual processingArtificial intelligence
• Fundamental Neuroscience
  openalex 2013-01-01 置信度 0.72 NeuroscienceCognitive sciencePsychology
• Computational Neuroscience
  This book is a collection of papers presented at a 1987 meeting that was, at least, partly intended to "define the field." It gathers papers from many of the most important contributors to computation neuroscience. Each author has written a chapter on some asp…
  openalex J. L. Ringo 1991-02-01 置信度 0.72 Computational neurosciencePresentation (obstetrics)Theme (computing)Cognitive scienceComputer science
• The neurosciences. Third study program
  openalex John N. Walton 1975-09-01 置信度 0.72 PsychologyCognitive science
• Neuroscience of apathy and anhedonia: a transdiagnostic approach
  openalex Masud Husain, Jonathan P. Roiser 2018-06-26 置信度 0.72 ApathyAnhedoniaPsychologyCognitive psychologyNeuroscience
• Consciousness without a cerebral cortex: A challenge for neuroscience and medicine
  A broad range of evidence regarding the functional organization of the vertebrate brain - spanning from comparative neurology to experimental psychology and neurophysiology to clinical data - is reviewed for its bearing on conceptions of the neural organizatio…
  openalex Bjørn Merker 2007-02-01 置信度 0.72 NeuroscienceBrainstemCerebral cortexConsciousnessMidbrain
• The Cognitive neurosciences
  Each edition of this classic reference has proved to be a benchmark in the developing field of cognitive neuroscience. The fourth edition of The Cognitive Neurosciences continues to chart new directions in the study of the biologic underpinnings of complex cog…
  openalex 2005-09-01 置信度 0.72 CognitionCognitive sciencePsychologyCognitive psychologyComputer science
• A method for estimating functional connectivity corrected for the effects of the local hemodynamic response and its application to the diagnosis of schizophrenia.
  Functional connectivity, an index that quantifies temporal correlations between activities in different brain regions, has attracted attention for its potential applications in the diagnosis and pathological understanding of psychiatric disorders. Functional c…
  pubmed Tanabe R, Niinuma T, Sugino M, Amemiya S 等 2026 Sep 置信度 0.82
• Addressing connectomic constraints in early practice of awake-guided neurosurgery: a four-year prospective case-matched analysis.
  Awake functional-guided resection (AFGR) is the gold-standard approach in glioma surgery. The learning curve associated with mastering white matter tracts (WMT) identification using direct electrostimulation (DES) mapping remains poorly characterized. The goal…
  pubmed Ng S, Otamendi-Lopez A, Martin B, Chalard K 等 2026 Jul 16 置信度 0.82
• The Cerebellar Connectome.
  The cerebellum, long known for its role in motor control, has increasingly been implicated in cognitive and affective functions. Despite this broadened perspective, its connectivity remains undercharacterized relative to the cerebral cortex. Here, we present t…
  pubmed Schmitt O, Morawska P, Prathapan V, Eipert P 2026 Jul 16 置信度 0.82
• Optimizing brain functional-structural architecture with cTBS to reduce relapse in alcohol use disorder: a randomized controlled trial.
  Alcohol use disorder (AUD) is characterized by high relapse rates, necessitating novel interventions. Continuous theta-burst stimulation (cTBS) targeting the right dorsolateral prefrontal cortex (rDLPFC) has been proposed to reduce relapse risk by modulating p…
  pubmed Wu ZK, Zhao JN, Zeng NN, Huang LJ 等 2026 Jul 15 置信度 0.82
• Deep brain stimulation for the treatment of patients with dystonia: advances towards network-based personalised care.
  Dystonia is a complex movement disorder that can cause functional disability and reduce quality of life. Deep brain stimulation (DBS) provides meaningful benefits in patients with medically refractory dystonia, but clinical outcomes can vary substantially. Thi…
  pubmed Latorre A, Peall KJ, Horn A, Pisani A 等 2026 Aug 置信度 0.82
• Changes in resting-state functional connectivity linked to affective symptoms: insights from a population-based study of adolescents and young adults.
  First episodes of affective disorders often emerge during adolescence and young adulthood. Alterations in resting-state functional connectivity (RSFC) have been reported in affective disorders, yet findings are heterogeneous and associations of RSFC with subcl…
  pubmed Henneberg PM, Beesdo-Baum K, Marxen M, Joshi G 等 2026 Jul 15 置信度 0.82
• Mapping the movie-watching brain with AI-derived semantics.
  Naturalistic paradigms offer a powerful tool to investigate human brain function, but it remains difficult to link rich, continuous movie content to distributed brain activity in an interpretable way. In this study, I use a multimodal large language model (Gem…
  pubmed Li M 2026 置信度 0.82
• Altered reward-related resting-state network properties in adolescent cannabis use and depression.
  Cannabis use among adolescents with depression is prevalent. Dysfunction of the reward system has been implicated in each condition separately, yet rarely examined together. Here, we investigated resting-state properties of reward networks in an adolescent sam…
  pubmed Nguyen TNB, Tobe RH, Ely BA, Gabbay V 2026 Jul 13 置信度 0.82
• Control of walking direction by descending and dopaminergic neurons in Drosophila.
  Animals fine-control the speed and direction of locomotion to navigate complex and dynamic environments. To achieve this, they integrate multimodal sensory cues with their internal drive to constantly adjust motor output. This involves the interplay of neurona…
  pubmed Liessem S, Dahlhoff S, Iqbal FM, Palacios-Muñoz A 等 2026 Aug 3 置信度 0.82
• Structured sampling of molecularly classified mossy fiber inputs by cerebellar granule cells.
  The cerebellar granule cell layer receives mossy fiber inputs from diverse brain regions, yet the principles governing how individual granule cells sample distinct types of inputs remain poorly understood. Using a volumetric correlated light and electron micro…
  pubmed Han X, Meral ES, Lichtman JW 2026 置信度 0.82
• A coupled node-network dynamics with Koopman and Krankheit-operators.
  The brain can be described as a network of nodes and links between them, the connectome, either anatomic or functional, containing information on the neural pathways and the signal exchanged across them. Recent studies proposed the Krankheit-operator (K-operat…
  pubmed Mannone M 2026 Jul 1 置信度 0.82
• Synergistic entrainment: a multiscale neurodynamic framework for closed-loop cross-modal neuromodulation.
  The brain's higher cognitive functions rely on the dynamic integration of multimodal information, supported by coordinated neural oscillations. However, current neuromodulation approaches often fail to reliably control these dynamics due to high inter-individu…
  pubmed Yan C, Zhang S, Li Y, Zhou Q 等 2026 Dec 置信度 0.82
• A high-resolution functional network-organized atlas of human superficial white matter from ultra-high-field diffusion MRI.
  Superficial white matter (SWM) supports local cortico-cortical communication. Still, its whole-brain organization remains difficult to characterize in vivo , due to its short length, high curvature, proximity to the gray-white matter interface, and individual …
  pubmed He Y, Xie Y, Yip H, Hong Y 等 2026 Jul 17 置信度 0.82
• DEEP-GYRALNET: ENABLING MACHINE LEARNING IN GYRAL FOLDING PATTERN EXTRACTION ON CORTICAL SURFACE.
  The 3-hinge gyrus (3HG), where three gyri converge, acts as a structural and functional hub in the brain. Connecting these hubs forms the GyralNet, but traditionally extraction requires complex geometric steps, limiting scalability. To address this challenge, …
  pubmed Cao C, Cheng J, Chen M, Zhang J 等 2026 置信度 0.82
• Neurobiological subtypes in alcohol use disorder and their phenotypic and clinical profiles.
  Alcohol Use Disorder (AUD) is associated with vast clinical, behavioral, and neurobiological heterogeneity that hinder both the efficacy of current interventions and future treatment development. While recent efforts have focused on stratifying psychiatric dis…
  pubmed Brucar LR, Rawls E, Zilverstand A 2026 Jul 11 置信度 0.82
• Beyond radiogenomics: advancing imaging integration and multi-omics horizons in cancer precision medicine.
  Cancer remains the leading cause of death worldwide, presenting substantial challenges to precision medicine due to its complex heterogeneity. Radiogenomics, as a method combining quantitative radiologic data with genomic information, provides a robust analysi…
  pubmed Chen Y, Li H, Chen S, Ji H 等 2026 Jul 11 置信度 0.82
• White Matter Perivascular Space Burden in Children With Autism Spectrum Disorder and Typically Developing Controls: An Automated Quantitative MRI Study.
  Perivascular spaces (PVS) are compartments involved in brain waste clearance. PVS are commonly observed in typically developing (TD) children; however, their burden in autism spectrum disorder (ASD) remains unclear.
  pubmed Girardi C, Peruzzo D, Castellotti F, Mani E 等 2026 Jul 11 置信度 0.82
• Supramaximal resection in gliomas: a narrative review of surgical techniques, clinical outcomes, and ethical considerations.
  Supramaximal resection (SMR) represents an evolving frontier in glioma surgery, extending tumor removal beyond conventional contrast-enhancing margins on magnetic resonance imaging (MRI) to include infiltrative, non-contrast-enhancing regions. Rooted in the un…
  pubmed Patel T, Ibrahim HY, Mukhtar MF, Tariq H 等 2026 Jul 置信度 0.82
• Cognitive network plasticity across divergent aging trajectories: an exploratory graph-theoretic study.
  Interindividual variability in response to cognitive training remains a key barrier to developing precision approaches for maintaining neurocognitive health across the lifespan. Characterizing changes in system-level cognitive reorganization may provide insigh…
  pubmed Coniglione M, Figini S, Assecondi S 2026 Jul 10 置信度 0.82
• Aberrant recovery of timescale-aligned amplitude balance links to symptoms and cognition in schizophrenia.
  Schizophrenia involves well-documented disruptions of large-scale brain coordination, but how strongly networks engage one another, and how that engagement recovers when disrupted, remains poorly understood. We identify amplitude proportionality, the maintenan…
  pubmed Wiafe SL, Kinsey S, Soleimani N, Nsafoa RO 等 2026 Jul 10 置信度 0.82
• Correlation between resumption of employment and overall survival following awake mapping-based surgery for IDH-mutant grade 2 glioma: a consecutive series with 515 patients.
  Although the life expectancy after surgery for IDH-mutant grade 2 glioma (G2G) is now approximately 20 years, the resumption of postresection employment has received little attention. The aim of this study was to identify factors associated with return to work…
  pubmed Duffau H 2026 Jul 10 置信度 0.82
• Remote network for cognitive symptoms derived from tau accumulation in progressive supranuclear palsy.
  Progressive supranuclear palsy (PSP) is a neurodegenerative disorder with motor and cognitive impairments. Whereas motor symptoms are associated with subcortical tau deposits, the mechanisms underlying the cognitive symptoms remain unclear due to heterogeneous…
  pubmed Hori Y, Endo H, Tagai K, Kataoka Y 等 2026 Jul 10 置信度 0.82
• Brain Graph Sparsification for fMRI-based Connectome Analysis: A Methodological Review.
  Functional magnetic resonance imaging (fMRI) is widely used to characterize functional brain organization through graph-based connectome analysis. However, functional connectivity networks constructed using Pearson correlation are typically dense and noisy, wh…
  pubmed Dai P, Chen L, Guo S, Huang K 等 2026 Jul 10 置信度 0.82
• Structural Connectome Alterations in Alternating Hemiplegia of Childhood.
  This study investigated structural connectivity in Alternating Hemiplegia of Childhood (AHC) using advanced tractography and connectome analysis, as characterizing brain network alterations in this rare disorder may clarify its cognitive and motor impairments.…
  pubmed Severino M, Pisciotta L, Tortora D, Trò R 等 2026 Jul 10 置信度 0.82
• Low effective dimensionality of the human functional connectome does not invalidate lesion network mapping
  Van den Heuvel et al. argued that the low effective dimensionality of the human connectome causes lesion network maps to converge on a common pattern, the connectome degree map, and concluded that the method cannot resolve distinct symptom-specific circuits. H…
  europepmc 2026 置信度 0.80
• Associations between neuronavigated rTMS-mediated functional connectome plasticity and neurotransmitter receptors in Alzheimer's disease.
  Introduction Cognitive improvement is mediated by repetitive transcranial magnetic stimulation (rTMS) in Alzheimer's disease (AD), and connectome gradient analysis has important potential to explore more comprehensive information for treatment efficacy. Howeve…
  europepmc 2026 置信度 0.80
• Connectome-based mapping of gray matter abnormalities in hepatic encephalopathy.
  Objective Hepatic encephalopathy (HE) is linked to widespread gray matter abnormalities, but it remains unclear whether these changes follow the organizing principles of large-scale brain networks. This study examined the spatial distribution of gray matter ab…
  europepmc 2026 置信度 0.80
• The Cerebellar Connectome.
  The cerebellum, long known for its role in motor control, has increasingly been implicated in cognitive and affective functions. Despite this broadened perspective, its connectivity remains undercharacterized relative to the cerebral cortex. Here, we present t…
  europepmc 2026 置信度 0.80
• Resting-state EEG connectome topology and social norm processing in healthy young adults.
  Resting-state network topology may provide a powerful framework for understanding how large-scale brain organisation supports cognitive functions. However, the topological correlates of social cognition remain poorly characterised. This study examined whether …
  europepmc 2026 置信度 0.80
• Axon Diameter Mapping in the Living Human Brain with Ultra-High-Gradient Diffusion MRI at 500 mT/m Gradient Strength.
  Pushing the resolution limit of axon diameter mapping in the living human brain requires higher gradient strength than is currently available on most clinical MRI systems. The noninvasive quantification of axon diameter not only enables the exploration of axon…
  europepmc 2026 置信度 0.80
• Dissecting the Strain and Sex Specific Connectome Signatures of Unanesthetized C57BL/6J and DBA/2J Mice Using Magnetic Resonance Imaging.
  Mouse models are an essential tool for understanding behavior and disease states in neuroscience research. While genetic and sex-specific effects have been reported in many neurodegenerative and psychiatric illnesses, these factors may also alter baseline neur…
  europepmc 2026 置信度 0.80
• Graph-based stochastic modelling of glioblastoma invasion using patient-specific structural brain connectomes
  Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults with extremely poor prognosis. Complete surgical treatment is practically impossible, as the true extent of GBM infiltration cannot be fully delineated using currently…
  europepmc 2026 置信度 0.80
• Cascading Periods of Language-Related Brain Plasticity Across Early Childhood.
  Language is thought to have multiple sensitive periods in early childhood, but the neural basis of these sensitive periods is less understood. We leverage advances in in-vivo neuroimaging of plasticity, measuring the neural inhibition across the brain via Hurs…
  europepmc 2026 置信度 0.80
• Connectome-scale self-supervised representation learning reveals neuronal organization beyond canonical labels
  Dense electron-microscopy connectomes provide synaptic-resolution maps of neuronal structure and wiring, but learning scalable representations that integrate structure and connectivity for connectome discovery with minimal human intervention remains difficult.…
  europepmc 2026 置信度 0.80
• Pre-Training for Large-Scale Functional Connectome Fingerprinting Supports Generalization and Transfer Learning in Functional Neuroimaging.
  Functional MRI (fMRI) currently supports a limited application space stemming from modest dataset sizes, large interindividual variability, and heterogeneity among scanning protocols. These constraints have made it difficult for fMRI researchers to take full a…
  europepmc 2026 置信度 0.80
• Brain Graph Sparsification for fMRI-based Connectome Analysis: A Methodological Review.
  Functional magnetic resonance imaging (fMRI) is widely used to characterize functional brain organization through graph-based connectome analysis. However, functional connectivity networks constructed using Pearson correlation are typically dense and noisy, wh…
  europepmc 2026 置信度 0.80
• Representational geometry as a fidelity metric for connectome-constrained networks: evidence from the <i>Drosophila</i> visual system
  What does biological wiring actually contribute to neural computation? Behavioral experiments can test whether a model produces the right outputs, but they cannot determine whether its internal representations are biologically faithful. Brunton et al. (2026) m…
  europepmc 2026 置信度 0.80
• Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease.
  Introduction Mild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD), shows pronounced clinical heterogeneity poorly explained by pathology burden, representing a gap complicating prognosis. As the brain operates as a complex network for…
  europepmc 2026 置信度 0.80
• NeuroMArVL: An interactive and collaborative web-based tool for visualizing brain networks.
  Brain connectivity data are high-dimensional and are often modeled as graphs comprising in the order of ∼10 2 -10 4 nodes connected by around 10 3 -10 6 edges. Generating useful visualizations is essential for reducing and understanding such complexity. Indeed…
  europepmc 2026 置信度 0.80
• Shared spatial and temporal principles govern connectome dynamics across timescales.
  While the brain processes information at various speeds, little is known about how the functional connectome can concurrently support multiple speeds in parallel. FMRI and electrophysiological modalities have been used to study connectome dynamics at slow and …
  europepmc 2026 置信度 0.80
• Is the whole more than the sum of its parts? Considering global and local features of the connectome improves prediction of individuals and phenotypes.
  Popular methods for analyzing the brain's functional connectome examine statistical associations between pairs of atlas-defined brain regions, viewing the strength of these links as independent values. However, edges within a standard connectivity matrix, that…
  europepmc 2026 置信度 0.80
• Metabolism-weighted brain connectome reveals synaptic integration and vulnerability to neurodegeneration.
  The brain's capacity for integration arises from both its structural wiring and energetically demanding electrochemical signaling. Yet current connectome analyses treat network nodes as functionally homogeneous, ignoring that neural communication is constraine…
  europepmc 2026 置信度 0.80
• Commentary: White matter functional connectome gradient dysfunction in major depressive disorder.
  Shangping Cheng, Bing Chen, Jing Lu; Commentary: White matter functional connectome gradient dysfunction in major depressive disorder, Psychoradiology, , k
  europepmc 2026 置信度 0.80
• Lesion-informed connectome diffusion modelling for individualized prediction of post-stroke brain atrophy
  Abstract Remote brain atrophy after stroke is clinically consequential but difficult to predict at the individual-patient level. Here we developed a lesion-informed connectome diffusion modelling framework to forecast distributed grey matter volume (GMV) atrop…
  europepmc 2026 置信度 0.80
• Organization of circuits linking descending input to motor output in the &lt;i&gt;Drosophila&lt;/i&gt; Male Adult Nerve Cord connectome.
  In most animals, a small number of descending neurons (DNs) connect the brain to circuits and motor neurons (MNs) in the nerve cord. To understand how brain signals generate behavior, it is critical to understand the organization of the neural pathways linking…
  pubmed Cheong HSJ, Eichler K, Stürner T, Asinof SK 等 2026 置信度 0.82
• From topography to connectome: Towards an integrated understanding of the resting brain
  As the field expands from early research into the human connectome, there has been a fast expansion in the number of analytical approaches to study resting state functional MRI (rsfMRI) data. With increasing focus on individual differences, topographical brain…
  europepmc 2026 置信度 0.80
• Brain Connectivity Modelling Through Joint Estimation of Parcels and Gradients
  This paper presents a framework for modelling the topography of whole-brain connectivity in resting-state functional MRI. The aim is to disentangle functional segregation, which manifests as abrupt changes in connectivity, from so-called gradients, i.e., smoot…
  europepmc 2026 置信度 0.80
• Mapping the functional connectome between grey matter and white matter.
  Brain white matter (WM) has traditionally been viewed as a passive conduit for neural transmission. However, evidence of blood oxygen level-dependent (BOLD) signals measured from the WM suggests its active participation in grey matter (GM) functional networks.…
  europepmc 2026 置信度 0.80
• Formic Acid Enhanced Single-Pot Sample Preparation to Improve Identification Coverage of Membrane Proteome of Laser Capture Microdissected Tissue Sections.
  To interpret the heterogeneous multicellular microenvironment in biological tissues, cell type-resolved global proteome profiling has attracted great attention. Due to its high compatibility with mass spectrometry (MS), n-Dodecyl-d-maltoside (DDM) is commonly …
  europepmc 2026 置信度 0.80
• A longitudinal resource for mapping interindividual variation in the aging connectome.
  Trajectories of age-related neurocognitive decline are nonuniform, and are impacted by numerous environmental and physiological factors. Earlier life phases set the stage for later life neurocognitive function, with midlife marking a critical transition charac…
  europepmc 2026 置信度 0.80
• Energy-efficient information processing and eligibility-trace plasticity in the Drosophila optic lobe connectome.
  Sensory circuits operate under finite metabolic budgets, so their information processing should be evaluated together with energetic cost. Using structural graph models, connectome-constrained dynamics, and an explicit energy proxy, we quantify energy-informat…
  europepmc 2026 置信度 0.80
• Directed Human Structural Connectome Reveals Hierarchical Organization and Shapes Large-Scale Brain Dynamics
  The human structural connectome, most commonly derived from diffusion-weighted imaging (DWI) and tractography, provides a macroscopic description of whole-brain wiring and serves as the structural foundation of network neuroscience, large-scale brain simulatio…
  europepmc 2026 置信度 0.80
• White matter functional connectome topology and its clinical correlations in adolescent major depressive disorder.
  Background Adolescence is a critical period for brain network remodeling and the onset of major depressive disorder (MDD); however, white matter (WM) functional topology in adolescent MDD remains underexplored. Given that WM functional signals reflect meaningf…
  europepmc 2026 置信度 0.80
• Multiscale structural connectome eigenmodes constrain human brain functional dynamics.
  The human brain is an intricate network structurally organized across multiple scales. Multiscale structural architecture arises from complex biological mechanisms and provides the anatomical substrate for functional interactions. However, the extent to which …
  europepmc 2026 置信度 0.80
• A global molecular code for birth order and neuronal identity in Drosophila.
  The assembly of functional neural circuits relies on the generation of diverse neural types with precise molecular identity and connectivity. Unlocking general principles of neuronal specification and wiring across the nervous system requires a systematic and …
  europepmc 2026 置信度 0.80
• Functional connectome signature of general psychopathology in middle-aged and older adults: Evidence from multi-cohort, multi-ethnic analyses.
  Mental health disorders are increasingly prevalent in middle-aged and older adults, a population undergoing substantial brain network reorganization. We aimed to identify whole-brain connectivity patterns associated with transdiagnostic psychiatric dimensions …
  europepmc 2026 置信度 0.80
• Dancing to the beats of the mammalian connectome: Topological and dynamical asymmetries shape infra-slow oscillations
  Flexible brain network dynamics unfold on several timescales, despite being constrained by a relatively static structural connectome. Recent cross-species evidence has described infra-slow network modulation, < 0.1 Hz, through two distinct but fundamentally al…
  europepmc 2026 置信度 0.80
• Microscopic connectome-based disease epicenter diffusion patterns in early-onset schizophrenia
  Abstract Background Early-onset schizophrenia (EOS) emerges during brain maturation, yet its neuropathologic mechanisms remain poorly understood. Based on the concept that pathological disturbances may propagate via the brain connectome, this study aims to del…
  europepmc 2026 置信度 0.80
• GCBM-DCT-HV-Bio-NL-Grow-CHG-CSM-RHEC: A Unified Geometric, Biological, Causal, and Regenerative Framework for Mechanism-Aware Tissue and Connectome Modeling
  Modern biological prediction problems increasingly require models that go beyond Euclidean feature regression and local graph smoothing. Tissue, cellular, and connectome systems are nonlinear, geometry-dependent, intervention-sensitive, history-dependent, and …
  europepmc 2026 置信度 0.80
• DigiMus: a connectome-informed spiking framework for multi-region mouse neural-behavior modeling
  Computational models are increasingly used to relate mouse brain structure, neural activity and behavior, but most models still learn from task data with limited constraints from biological circuit organization. Here we present DigiMus, a connectome-informed s…
  europepmc 2026 置信度 0.80
• One operator to rule them all: Unifying connectome harmonics, turbulence and complex harmonics in brain dynamics
  Brain dynamics can be described in three different convenient mathematical languages, namely connectome harmonics, turbulence and complex harmonics (CHARM). Here we demonstrate that these theoretical frameworks can be rigorously unified, under the functional c…
  europepmc 2026 置信度 0.80
• Functional Connectome Predicts Cognition and Links White Matter Hyperintensity Burden to Cognitive Impairment Across the Vascular Cognitive Impairment Continuum.
  Background : White matter hyperintensity (WMH) is a hallmark of cerebral small vessel disease and an important contributor to vascular cognitive impairment (VCI), yet lesion burden incompletely explains interindividual variability in cognitive outcomes across …
  europepmc 2026 置信度 0.80
• Bayesian generative modeling reveals a multi-modal hierarchical architecture in the mouse functional connectome
  Understanding the principles governing large-scale functional organization of the brain remains a central challenge in systems neuroscience. Despite convergent findings, substantial variability across analytical approaches suggests that functional networks may…
  europepmc 2026 置信度 0.80
• Structural Connectome Alterations in Alternating Hemiplegia of Childhood.
  This study investigated structural connectivity in Alternating Hemiplegia of Childhood (AHC) using advanced tractography and connectome analysis, as characterizing brain network alterations in this rare disorder may clarify its cognitive and motor impairments.…
  pubmed Severino M, Pisciotta L, Tortora D, Trò R 等 2026 置信度 0.82
• Gliomas as network diseases: Neuron-tumor interactions, connectome disruption, and clinical implications.
  Background Gliomas are increasingly understood as disorders of distributed brain networks rather than focal lesions confined within radiographic margins. Emerging evidence suggests that glioma cells interact with neural circuits, alter structural and functiona…
  europepmc 2026 置信度 0.80
• Structural connectome architecture and biological vulnerability shape cortical atrophy in cocaine use disorder.
  Background Cocaine use disorder (CUD) is highly prevalent and characterized by widespread gray matter atrophy across the cerebral cortex. Yet, it remains unclear whether and how connectome-based circuits and biological features shape these structural abnormali…
  europepmc 2026 置信度 0.80
• A coupled node-network dynamics with Koopman and Krankheit-operators.
  The brain can be described as a network of nodes and links between them, the connectome, either anatomic or functional, containing information on the neural pathways and the signal exchanged across them. Recent studies proposed the Krankheit-operator (K-operat…
  europepmc 2026 置信度 0.80
• Disrupted Geometric Constraints on Connectome Wiring in Children and Adolescents with ADHD
  Attention-deficit/hyperactivity disorder (ADHD) is thought to result from aberrant neurodevelopmental wiring of connectome architecture, yet the precise mechanisms underpinning this miswiring remain unclear. Here, we used a generative mathematical model to und…
  europepmc 2026 置信度 0.80
• Connectome-guided personalization of optimal tDCS intervention selection in Alzheimer's disease: A modeling study.
  Transcranial direct current stimulation (tDCS) could reduce the neurophysiological effects in Alzheimer's disease (AD), but progress is hampered by variable outcomes across studies, likely related to both methodological and individual differences. We recently …
  europepmc 2026 置信度 0.80
• In-patient treatment and structural dysconnectivity in major depression - A longitudinal connectome study.
  Altered brain structural connectivity has been implicated in the pathophysiology of Major Depressive Disorder (MDD), yet its stability over time and responsiveness to treatment remain unclear. This study utilized network science to analyze the white matter con…
  europepmc 2026 置信度 0.80
• The microstructure-weighted human connectome: network properties and structure-function correlations across spatial scales
  Conventional connectome edge weights, such as number of streamlines (NOS) or diffusion tensor imaging (DTI) metrics, lack specificity to microstructural details which may hold relevance for macroscale brain organisation. Since biophysical diffusion modelling o…
  europepmc 2026 置信度 0.80
• Increasing the Reliability of Functional Connectivity by Predicting Long-Scan Functional Connectivity based on Short-Scan Functional Connectivity: Model Exploration, Explanation, Validation, and Application.
  Functional connectivity (FC) is a widely used metric in functional magnetic resonance imaging (fMRI) research. However, its reliability has long been a notable concern, especially in studies with small sample sizes. Previous research has demonstrated that FC d…
  europepmc 2026 置信度 0.80
• A common connectome-based neural reference space across affective, autonomic, and wakefulness arousal
  Arousal is often invoked to explain state-dependent variability in attention, emotion, memory, and decision-making. However, the term is used inconsistently, referring variously to affective experience, autonomic activation, and states of wakefulness. The exte…
  europepmc 2026 置信度 0.80
• Resting-state functional connectome correlates of suicide attempt history and childhood trauma in major depressive disorder.
  Background A prior suicide attempt is the strongest predictor of subsequent suicide mortality in major depressive disorder (MDD); however, the functional network architecture distinguishing individuals with and without a history of suicide attempts remains inc…
  europepmc 2026 置信度 0.80
• Optimization of connectome weights for a neural network model generating both forward and backward locomotion in C. elegans.
  Previous studies tracking the relationship between manipulations of C. elegans neurons and the resulting behavioral changes have called for the development of a connectome-constrained neural network model that describes the cascade from neurons to behavior. Ho…
  europepmc 2026 置信度 0.80
• Emerging paradigms in connectome-guided neurosurgery for central nervous system tumors: a narrative review of structural and functional connectomics.
  Connectomics is a comprehensive mapping of structural and functional brain networks. It has introduced a paradigm shift in neurosurgery by redefining brain tumors as network disorders rather than isolated lesions. Unlike traditional surgeries, connectome-guide…
  europepmc 2026 置信度 0.80
• The degenerome-a novel streamline-wise approach for white matter integrity in neurodegeneration.
  Neurodegenerative diseases impair both gray matter and long-range white-matter pathways. Existing diffusion MRI approaches are either local or depend on predefined parcellations, limiting their ability to capture distributed network disruption. We introduce a …
  europepmc 2026 置信度 0.80
• A connectome-based neural correlate of pediatric ADHD hyperactivity-impulsivity symptoms.
  Background This study examined the brain networks related to hyperactivity and impulsivity in children with Attention-Deficit/Hyperactivity Disorder (ADHD) and aimed to develop a resting-state functional connectivity marker that can predict symptom severity. M…
  europepmc 2026 置信度 0.80
• ViTAE-HGOT: Vision Transformer-based Autoencoder with Hypergraph Optimal Transport for cross-atlas functional connectome remapping.
  The utilization of open-source neuroimaging datasets, despite their unprecedented sample scale, poses significant challenges to cross-study comparability and multi-site data fusion due to the use of different brain atlases that generate inconsistent functional…
  europepmc 2026 置信度 0.80
• Bridging molecules and connectome: network biomarkers guided by neurotransmitter architecture in major depressive disorder.
  Major depressive disorder (MDD) involves multiscale alterations ranging from molecular signaling to large-scale brain network dysfunction. However, how molecular topography constrains system-level connectome reorganization remains inadequately understood, limi…
  europepmc 2026 置信度 0.80
• Efficient ageing: Simulated lesion of the structural connectome reveals optimised decline in the healthy ageing brain
  Healthy ageing is associated with widespread white-matter change and altered connectome organisation, yet the link between local microstructural decline and whole-brain network communication remains unclear. Here we combined tract-based spatial statistics (TBS…
  europepmc 2026 置信度 0.80
• Signed motif analysis of the Caenorhabditis elegans neuronal network reveals positive feedforward and negative feedback loops.
  Background Nervous systems are complex biological networks with largely unknown structural and functional characteristics. Motif analysis is a robust tool that can reveal the unique aspects of connectivity in a complex network. An ideal candidate for motif ana…
  europepmc 2026 置信度 0.80
• Towards precision EEG connectomics: Evaluating the benefits of dense sampling.
  EEG connectomics research offers the potential to better understand human neurodevelopment, brain disorders, and brain-behavior associations. Several functional connectivity (FC) measures are widely used but few studies have directly compared metrics of reliab…
  europepmc 2026 置信度 0.80
• FedFound: a federated foundation model for lifespan brain morphological connectome analysis.
  The brain morphological connectome derived from structural MRI reflects inter-regional morphological relationships, providing a powerful representation for characterizing individual variability and detecting abnormalities across the lifespan. However, these ab…
  europepmc 2026 置信度 0.80
• Mapping the Disrupted Connectome in Spinocerebellar Ataxia Type 3: A Network-Based Statistics Study Identifying Novel Therapeutic Targets for Neuromodulation.
  Aims Spinocerebellar ataxia type 3 (SCA3) is characterized by progressive neurodegeneration. This study aimed to map alterations in structural and functional connectivity (SC and FC) in SCA3 using network-based statistics (NBS) and to explore the potential of …
  europepmc 2026 置信度 0.80