-
openalex
Elizabeth Gould, Patima Tanapat
1999-12-01
置信度 0.72
Dentate gyrusHippocampal formationNeurogenesisGranule cellNeuroscience
-
openalex
Abner Louissaint, Sudha Rao, Caroline Leventhal, Steven A. Goldman
2002-06-01
置信度 0.72
SongbirdNeurogenesisNeuroscienceAngiogenesisPsychology
-
openalex
Daniel A. Lim, Anthony D. Tramontin, José Trevejo, Daniel G. Herrera 等
2000-12-01
置信度 0.72
NogginNeurogenesisBone morphogenetic proteinNicheNeuroscience
-
openalex
Kirsty L. Spalding, Olaf Bergmann, Kanar Alkass, Samuel Bernard 等
2013-06-01
置信度 0.72
NeurogenesisHippocampal formationBiologyNeuroscienceHippocampus
-
The thin lamina between the hippocampal hilus and granule cell layer, or subgranule zone (SGZ), is an area of active proliferation within the adult hippocampus known to generate new neurons throughout adult life. Although the neuronal fate of many dividing cel…
openalex
Theo D. Palmer, Andrew R. Willhoite, Fred H. Gage
2000-01-01
置信度 0.72
NeurogenesisBiologyHippocampal formationNeuroscienceNeuroepithelial cell
-
Aging causes changes in the hippocampus that may lead to cognitive decline in older adults. In young animals, exercise increases hippocampal neurogenesis and improves learning. We investigated whether voluntary wheel running would benefit mice that were sedent…
openalex
Henriette van Praag, Tiffany E. Shubert, Chunmei Zhao, Fred H. Gage
2005-09-21
置信度 0.72
NeurogenesisHippocampal formationHippocampusMorris water navigation taskPsychology
-
Forty years since the initial discovery of neurogenesis in the postnatal rat hippocampus, investigators have now firmly established that active neurogenesis from neural progenitors continues throughout life in discrete regions of the central nervous systems (C…
openalex
Guo‐li Ming, Hongjun Song
2005-03-18
置信度 0.72
NeurogenesisNeuroscienceBiologyNeural stem cellCentral nervous system
-
openalex
Tracey J. Shors, George R. Miesegaes, Anna V. Beylin, Mingrui Zhao 等
2001-03-15
置信度 0.72
NeurogenesisHippocampal formationNeuroscienceHippocampusEngram
-
New hippocampal neurons are continuously generated in the adult brain. Here, we demonstrate that lipopolysaccharide-induced inflammation, which gives rise to microglia activation in the area where the new neurons are born, strongly impairs basal hippocampal ne…
openalex
Christine T. Ekdahl, Jan-Hendrik Claasen, Sara Bonde, Zaal Kokaia 等
2003-10-27
置信度 0.72
NeurogenesisMicrogliaHippocampal formationInflammationNeuroscience
-
openalex
Heidi Phillips, Samir Kharbanda, Ruihuan Chen, William F. Forrest 等
2006-03-01
置信度 0.72
BiologyNeurogenesisLineage markersPTENGlioma
-
openalex
Elizabeth Gould, Anna V. Beylin, Patima Tanapat, Alison J. Reeves 等
1999-03-01
置信度 0.72
Hippocampal formationNeurogenesisDentate gyrusNeuroscienceHippocampus
-
openalex
Amar Sahay, René Hen
2007-08-28
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationNeuroscienceHippocampus
-
openalex
D. Chichung Lie, Sophia A. Colamarino, Hong-jun Song, Laurent Désiré 等
2005-10-01
置信度 0.72
NeurogenesisNeural stem cellSubgranular zoneHippocampal formationSubventricular zone
-
openalex
Saul Villeda, Jian Luo, Kira I. Mosher, Bende Zou 等
2011-08-30
置信度 0.72
NeurogenesisParabiosisNeural stem cellDoublecortinNeuroscience
-
During development of the central nervous system, expression of the microtubule binding protein doublecortin (DCX) is associated with migration of neuroblasts. In addition to this developmental role, expression of DCX remains high within certain areas of the a…
openalex
Jason P. Brown, Sébastien Couillard‐Després, Christiana M. Cooper‐Kuhn, Jürgen Winkler 等
2003-10-17
置信度 0.72
DoublecortinNeurogenesisNeuroblastDentate gyrusBiology
-
Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the most attention, because it is involved in higher cognitive function, most notably memory processes, and certain affective behaviors. Adult hippocampal neurogenesis is also …
openalex
Gerd Kempermann, Hongjun Song, Fred H. Gage
2015-09-01
置信度 0.72
BiologyNeurogenesisStem cellGerontologyNeuroscience
-
Much excitement has been generated by the identification of adult brain regions harboring neural stem cells and their continual generation of new neurons throughout life. This is an important departure from traditional views of the germinal potential of the po…
openalex
Arturo Álvarez-Buylla, José Manuel García‐Verdugo
2002-02-01
置信度 0.72
Subventricular zoneNeurogenesisNeural stem cellNeurosciencePsychology
-
The dentate gyrus (DG) of the mammalian hippocampus is hypothesized to mediate pattern separation-the formation of distinct and orthogonal representations of mnemonic information-and also undergoes neurogenesis throughout life. How neurogenesis contributes to …
openalex
Claire D. Clelland, Minee-Liane Choi, Carola Romberg, Gregory D. Clemenson 等
2009-07-09
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationNeuroscienceHippocampus
-
The development of most regions of the vertebrate nervous system includes a distinct phase of neuronal degeneration during which a substantial proportion of the neurons initially generated die. This degeneration primarily adjusts the magnitude of each neuronal…
openalex
William Cowan, James W. Fawcett, Dennis D.M. O’Leary, Brent B. Stanfield
1984-09-21
置信度 0.72
NeuroscienceAxonNeurogenesisDegeneration (medical)Biology
-
openalex
Maura Boldrini, Camille Fulmore, Alexandria Tartt, Laika R. Simeon 等
2018-04-01
置信度 0.72
NeurogenesisHippocampal formationDentate gyrusBiologyNeuroscience
-
openalex
Amar Sahay, Kimberly N. Scobie, Alexis S. Hill, C. O’Carroll 等
2011-04-01
置信度 0.72
NeurogenesisHippocampal formationDentate gyrusNeurosciencePsychology
-
openalex
Sanjay S. P. Magavi, Blair R. Leavitt, Jeffrey D. Macklis
2000-06-01
置信度 0.72
NeurogenesisNeocortexNeuNOlfactory bulbBiology
-
openalex
Jason S. Snyder, Amélie Soumier, Michelle Brewer, James Pickel 等
2011-08-01
置信度 0.72
NeurogenesisHippocampal formationHippocampusDentate gyrusBehavioural despair test
-
openalex
Wei Deng, James B. Aimone, Fred H. Gage
2010-03-31
置信度 0.72
NeurogenesisHippocampal formationNeuroscienceDentate gyrusHippocampus
-
openalex
Pierre‐Marie Lledo, Mariana Alonso, Matthew S. Grubb
2006-02-22
置信度 0.72
NeurogenesisNeuroscienceDentate gyrusOlfactory bulbNeuroplasticity
-
We demonstrate here that under physiological conditions neurogenesis continues to occur in the dentate gyrus of senescent mice and can be stimulated by living in an enriched environment. Neurogenesis was investigated by confocal microscopy of three-channel imm…
openalex
Gerd Kempermann, H. Georg Kuhn, Fred H. Gage
1998-05-01
置信度 0.72
NeurogenesisBromodeoxyuridineDentate gyrusStimulationBiology
-
In primates, prefrontal, inferior temporal, and posterior parietal cortex are important for cognitive function. It is shown that in adult macaques, new neurons are added to these three neocortical association areas, but not to a primary sensory area (striate c…
openalex
Elizabeth Gould, Alison J. Reeves, Michael S. A. Graziano, Charles G. Gross
1999-10-15
置信度 0.72
NeocortexNeurogenesisNeuroscienceSubventricular zoneCortex (anatomy)
-
The dentate granule cell layer of the rodent hippocampal formation has the distinctive property of ongoing neurogenesis that continues throughout adult life. In both human temporal lobe epilepsy and rodent models of limbic epilepsy, this same neuronal populati…
openalex
Jack M. Parent, Timothy W. Yu, Rebecca T. Leibowitz, Daniel H. Geschwind 等
1997-05-15
置信度 0.72
Dentate gyrusNeurogenesisGranule cellHippocampal formationNeuroscience
-
openalex
Hongjun Song, Charles F. Stevens, Fred H. Gage
2002-05-01
置信度 0.72
NeurogenesisNeuroscienceNeural stem cellBiologyHippocampus
-
Neurogenesis, which persists in the adult mammalian brain, may provide a basis for neuronal replacement therapy in neurodegenerative diseases like Alzheimer's disease (AD). Neurogenesis is increased in certain acute neurological disorders, such as ischemia and…
openalex
Kunlin Jin, Alyson Peel, Xiao Mao, Lin Xie 等
2003-12-05
置信度 0.72
NeurogenesisDoublecortinDentate gyrusSubgranular zoneHippocampal formation
-
openalex
Shawn F. Sorrells, Mercedes F. Paredes, Arantxa Cebrián‐Silla, Kadellyn Sandoval 等
2018-03-01
置信度 0.72
Subgranular zoneDentate gyrusNeurogenesisHippocampal formationNeuroscience
-
Knowing the rate of addition of new granule cells to the adult dentate gyrus is critical to understanding the function of adult neurogenesis. Despite the large number of studies of neurogenesis in the adult dentate gyrus, basic questions about the magnitude of…
openalex
Heather A. Cameron, Ronald D.G. McKay
2001-06-08
置信度 0.72
Dentate gyrusNeurogenesisBromodeoxyuridineBiologyGranule cell
-
The hippocampus, a brain area critical for learning and memory, is especially vulnerable to damage at early stages of Alzheimer's disease (AD). Emerging evidence has indicated that altered neurogenesis in the adult hippocampus represents an early critical even…
openalex
Yangling Mu, Fred H. Gage
2011-01-01
置信度 0.72
NeurogenesisNeuroscienceHippocampal formationHippocampusDisease
-
Stroke causes cell death but also birth and migration of new neurons within sites of ischemic damage. The cellular environment that induces neuronal regeneration and migration after stroke has not been defined. We have used a model of long-distance migration o…
openalex
John J. Ohab, Sheila M. Fleming, Armin Blesch, S. Thomas Carmichael
2006-12-13
置信度 0.72
NeurogenesisSubventricular zoneNeuroblastNeuroscienceAngiogenesis
-
openalex
Aurélie Ernst, Kanar Alkass, Samuel Bernard, Mehran Salehpour 等
2014-02-01
置信度 0.72
BiologyNeurogenesisStriatumNeuroscienceHuman brain
-
openalex
Yaniv Ziv, Noga Ron, Oleg Butovsky, Gennady Landa 等
2006-01-15
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationNeuroscienceMicroglia
-
Abstract The properties and fate of the cells of the subependymal layer of the anterior lateral ventricle and its rostral extension into the olfactory bulb were examined. In one experiment, histological analysis was made of this structure in a large group of r…
openalex
Joseph Altman
1969-12-01
置信度 0.72
Subependymal zoneOlfactory bulbNeurogenesisBiologyRostral migratory stream
-
With continued debate over the functional significance of adult neurogenesis, identifying an in vivo correlate of neurogenesis has become an important goal. Here we rely on the coupling between neurogenesis and angiogenesis and test whether MRI measurements of…
openalex
Ana Catarina Pereira, Daniel E. Huddleston, Adam M. Brickman, Alexander A. Sosunov 等
2007-03-20
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationNeuroscienceHippocampus
-
openalex
Elena P. Moreno‐Jiménez, Miguel Flor‐García, Julia Terreros‐Roncal, Alberto Rábano 等
2019-03-25
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationNeuroscienceHippocampus
-
openalex
Denis J. David, Benjamin A. Samuels, Quentin Rainer, Jing-Wen Wang 等
2009-05-01
置信度 0.72
FluoxetineNeurogenesisCorticosteroneAntidepressantHippocampal formation
-
Progress in the field of neurogenesis is currently limited by the lack of tools enabling fast and quantitative analysis of neurogenesis in the adult brain. Doublecortin (DCX) has recently been used as a marker for neurogenesis. However, it was not clear whethe…
openalex
Sébastien Couillard‐Després, Beate Winner, Susanne Schaubeck, Robert Aigner 等
2005-01-01
置信度 0.72
NeurogenesisDoublecortinNeuroscienceGliogenesisBiology
-
The discovery that the adult mammalian brain creates new neurons from pools of stemlike cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural brain plasticity seems specific to discrete brain regions, and most investig…
openalex
Djoher Nora Abrous, Muriel Koehl, Michel Le Moal
2005-03-23
置信度 0.72
NeurogenesisNeuroscienceSubventricular zoneDentate gyrusHippocampal formation
-
Stress hormones have potent growth-inhibiting effects on a variety of peripheral tissues. Consistent with this general function, stress has been shown to inhibit cell proliferation and, ultimately, neurogenesis in the hippocampus. This effect appears to be com…
openalex
Christian Mirescu, Elizabeth Gould
2006-01-01
置信度 0.72
NeurogenesisNeuroscienceStressorHippocampusPsychology
-
openalex
Barry L. Jacobs, Henriette van Praag, Fred H. Gage
2000-05-01
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationNeurosciencePsychology
-
openalex
Amanda Sierra, Juan Manuel Encinas, Juan J. P. Deudero, Jessica H. Chancey 等
2010-10-01
置信度 0.72
Subgranular zoneMicrogliaNeuroblastNeurogenesisBiology
-
A milestone is marked in our understanding of the brain with the recent acceptance, contrary to early dogma, that the adult nervous system can generate new neurons. One could wonder how this dogma originally came about, particularly because all organisms have …
openalex
Fred H. Gage
2002-02-01
置信度 0.72
NeurogenesisWonderMilestoneNeuroscienceCognitive science
-
These studies were designed to determine whether adult neurogenesis occurs in the dentate gyrus of the tree shrew, an animal phylogenetically between insectivores and primates, and to explore the possibility that this process is regulated by stressful experien…
openalex
Elizabeth Gould, Bruce S. McEwen, Patima Tanapat, Liisa A.M. Galea 等
1997-04-01
置信度 0.72
Dentate gyrusNeurogenesisSubgranular zoneGranule cellNeuroscience
-
openalex
Heather A. Cameron, Elizabeth Gould
1994-07-01
置信度 0.72
Dentate gyrusNeurogenesisGranule cellInternal medicineEndocrinology
-
openalex
Itaru Imayoshi, Masayuki Sakamoto, Toshiyuki Ohtsuka, Keizo Takao 等
2008-08-31
置信度 0.72
NeurogenesisDentate gyrusOlfactory bulbNeuroscienceHippocampal formation
-
openalex
Christoph Anacker, René Hen
2017-05-04
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationCognitive flexibilityNeuroscience
-
To determine the role of brain-derived neurotrophic factor (BDNF) in the enhancement of hippocampal neurogenesis resulting from dietary restriction (DR), heterozygous BDNF knockout (BDNF +/-) mice and wild-type mice were maintained for 3 months on DR or ad lib…
openalex
Jaewon Lee, Wenzhen Duan, Mark P. Mattson
2002-09-01
置信度 0.72
NeurogenesisDentate gyrusBrain-derived neurotrophic factorNeurotrophic factorsEndocrinology
-
Three-month-old rats were injected intraperitoneally with [3H]thymidine (4.3 microcuries per gram of body weight) and allowed to survive for 30 days. Radioautography of 1-micrometer sections revealed labeled cells in the granular layers of dentate gyrus and ol…
openalex
Michael Kaplan, James W. Hinds
1977-09-09
置信度 0.72
NeurogenesisOlfactory bulbDentate gyrusElectron microscopeThymidine
-
The persistence of neurogenesis in the forebrain subventricular zone (SVZ) of adult mammals suggests that the mature brain maintains the potential for neuronal replacement after injury. We examined whether focal ischemic injury in adult rat would increase SVZ …
openalex
Jack M. Parent, Zinaida S. Vexler, Chao Gong, Nikita Derugin 等
2002-10-11
置信度 0.72
NeurogenesisNeuroblastSubventricular zoneBiologyForebrain
-
Neurogenesis in the dentate gyrus of adult rodents is regulated by NMDA receptors, adrenal steroids, environmental stimuli, and seizures. To determine whether ischemia affects neurogenesis, newly divided cells in the dentate gyrus were examined after transient…
openalex
Jialing Liu, Karen Solway, Robert O. Messing, Frank R. Sharp
1998-10-01
置信度 0.72
NeurogenesisDentate gyrusSubgranular zoneGranule cellNeuroscience
-
openalex
Charles G. Gross
2000-10-01
置信度 0.72
NeurogenesisNeuroscienceNeuroplasticityPerspective (graphical)Psychology
-
openalex
Torsten Madsén, Alexandra Treschow, Johan Bengzon, Tom G. Bolwig 等
2000-06-01
置信度 0.72
NeurogenesisDentate gyrusElectroconvulsive therapyNeuroscienceHippocampus
-
Declining learning and memory function is associated with the attenuation of adult hippocampal neurogenesis. As in humans, chronic stress or depression in animals is accompanied by hippocampal dysfunction, and neurogenesis is correspondingly down regulated, in…
openalex
Klaus Fabel, Konstanze Fabel, Betty Y. Tam, Daniela Kaufer 等
2003-11-01
置信度 0.72
NeurogenesisHippocampal formationNeurosciencePsychologyEndocrinology
-
openalex
Lei Cao, Xiangyang Jiao, David S. Zuzga, Yuhong Liu 等
2004-07-18
置信度 0.72
NeurogenesisHippocampal formationBiologyVascular endothelial growth factorNeuroscience
-
Early experiences such as prenatal stress significantly influence the development of the brain and the organization of behavior. In particular, prenatal stress impairs memory processes but the mechanism for this effect is not known. Hippocampal granule neurons…
openalex
Valérie Lemaire, Muriel Koehl, Michel Le Moal, Djoher Nora Abrous
2000-09-26
置信度 0.72
NeurogenesisDentate gyrusHippocampal formationPrenatal stressNeuroscience
-
openalex
Gerd Kempermann, Fred H. Gage, Ludwig Aigner, Hongjun Song 等
2018-04-19
置信度 0.72
NeurogenesisBiologyNeuroplasticityCognitive scienceNeuroscience
-
openalex
Jason S. Snyder, N.S. Hong, Robert J. McDonald, J. Martin Wojtowicz
2004-12-11
置信度 0.72
NeurogenesisHippocampal formationMemory consolidationNeuroscienceHippocampus
-
The production of new hippocampal neurons in adulthood has been well documented in rodents. Recent studies have extended these findings to other mammalian species, such as tree shrews and marmoset monkeys. However, hippocampal neurogenesis has not been demonst…
openalex
Elizabeth Gould, Alison J. Reeves, Mazyar Fallah, Patima Tanapat 等
1999-04-27
置信度 0.72
NeurogenesisHippocampal formationDentate gyrusBiologyMarmoset
-
We present evidence for continuous generation of neurons, oligodendrocytes, and astrocytes in the hippocampal dentate gyrus of adult macaque monkeys, using immunohistochemical double labeling for bromodeoxyuridine and cell-type-specific markers. We estimate th…
openalex
David R. Kornack, Pasko Rakić
1999-05-11
置信度 0.72
NeurogenesisDentate gyrusMacaqueNeuroscienceHippocampal formation
-
Neural stem cells are reported to lie in a vascular niche, but there is no direct evidence for a functional relationship between the stem cells and blood vessel component cells. We show that endothelial cells but not vascular smooth muscle cells release solubl…
openalex
Qin Shen, Susan K. Goderie, Jin Li, Nithin Karanth 等
2004-04-05
置信度 0.72
Neuroepithelial cellNeural stem cellCell biologyNeurosphereStem cell
-
openalex
Magdalena Bylund, Elisabet Andersson, Bennett G. Novitch, Jonas Muhr
2003-09-28
置信度 0.72
NeurogenesisBiologySOX2Cell biologyProneural genes
-
Vascular endothelial growth factor (VEGF) is an angiogenic protein with therapeutic potential in ischemic disorders, including stroke. VEGF confers neuroprotection and promotes neurogenesis and cerebral angiogenesis, but the manner in which these effects may i…
openalex
Yunjuan Sun, Kunlin Jin, Lin Xie, Jocelyn Childs 等
2003-06-15
置信度 0.72
PenumbraNeuroprotectionAngiogenesisNeurogenesisSubventricular zone
-
openalex
Eva Y.-H.P. Lee, Chi-Yao Chang, Nanpin Hu, Yi-Chun J. Wang 等
1992-09-01
置信度 0.72
RetinoblastomaBiologyHaematopoiesisNeurogenesisCarcinogenesis
-
openalex
Gerd Kempermann, Laurenz Wiskott, Fred H. Gage
2004-03-13
置信度 0.72
NeurogenesisNeuroscienceFunction (biology)PsychologyProcess (computing)
-
The hippocampus is one of several limbic brain structures implicated in the pathophysiology and treatment of mood disorders. Preclinical and clinical studies demonstrate that stress and depression lead to reductions of the total volume of this structure and at…
openalex
Jennifer Warner‐Schmidt, Ronald S. Duman
2006-01-01
置信度 0.72
NeurogenesisHippocampal formationHippocampusNeuroscienceAntidepressant
-
openalex
Christine T. Ekdahl, Zaal Kokaia, Olle Lindvall
2008-07-04
置信度 0.72
NeurogenesisSubventricular zoneMicrogliaNeuroblastSubgranular zone
-
openalex
Alex Dranovsky, René Hen
2006-06-01
置信度 0.72
NeurogenesisHippocampal formationAntidepressantNeurosciencePsychology
-
openalex
Elizabeth Gould
2007-05-19
置信度 0.72
NeurogenesisOlfactory bulbNeocortexNeuroscienceHippocampus
-
openalex
Ki‐Jun Yoon, Francisca Rojas Ringeling, Caroline Vissers, Fadi Jacob 等
2017-09-29
置信度 0.72
NeurogenesisBiologyForebrainCell biologyEmbryonic stem cell
-
Throughout life, new neurons are continuously added to the dentate gyrus. As this continuous addition remodels hippocampal circuits, computational models predict that neurogenesis leads to degradation or forgetting of established memories. Consistent with this…
openalex
Katherine G. Akers, Alonso Martínez-Canabal, Leonardo Restivo, Adelaide P. Yiu 等
2014-05-08
置信度 0.72
NeurogenesisHippocampal formationForgettingDentate gyrusNeuroscience
-
openalex
J. Tiago Gonçalves, Simon T. Schafer, Fred H. Gage
2016-11-01
置信度 0.72
NeurogenesisBiologyDentate gyrusNeuroscienceHippocampal formation
-
openalex
Anna V. Molofsky, Shalom Guy Slutsky, Nancy M. Joseph, Shenghui He 等
2006-09-01
置信度 0.72
NeurogenesisSubventricular zoneProgenitor cellOlfactory bulbBiology
-
Vascular endothelial growth factor (VEGF) is an angiogenic protein with neurotrophic and neuroprotective effects. Because VEGF promotes the proliferation of vascular endothelial cells, we examined the possibility that it also stimulates the proliferation of ne…
openalex
Kunlin Jin, Yonghua Zhu, Yunjuan Sun, Xiao Mao 等
2002-08-14
置信度 0.72
DoublecortinNeurogenesisAngiogenesisSubgranular zoneVascular endothelial growth factor
-
openalex
Henriette van Praag
2008-02-19
置信度 0.72
NeurogenesisDentate gyrusNeuroscienceHippocampal formationHippocampus
-
openalex
A. Denise R. Garcia, Ngan Doan, Tetsuya Imura, Toby G. Bush 等
2004-10-19
置信度 0.72
NeurogenesisNeuroblastSubgranular zoneBiologyForebrain
-
The mammalian brain exhibits diverse types of neural plasticity, including activity-dependent neurogenesis in the adult hippocampus. How transient activation of mature neurons leads to long-lasting modulation of adult neurogenesis is unknown. Here we identify …
openalex
K. Dengke, Mi‐Hyeon Jang, Junjie U. Guo, Yasuji Kitabatake 等
2009-01-01
置信度 0.72
NeurogenesisDNA demethylationHippocampal formationBiologyEpigenetics
-
Increasing evidence suggests that mood disorders are associated with a reduction in regional CNS volume and neuronal and glial cell atrophy or loss. Lithium, a mainstay in the treatment of mood disorders, has recently been demonstrated to robustly increase the…
openalex
Guang Chen, Grażyna Rajkowska, Fu Du, Navid Seraji‐Bozorgzad 等
2000-10-01
置信度 0.72
NeurogenesisDentate gyrusLithium (medication)HippocampusHippocampal formation
-
The hippocampal formation generates new neurons throughout adulthood. Recent studies indicate that these cells possess the morphology and physiological properties of more established neurons. However, the function of adult generated neurons is still a matter o…
openalex
Tracey J. Shors, David A. Townsend, Mingrui Zhao, Yevgenia Kozorovitskiy 等
2002-01-01
置信度 0.72
NeurogenesisHippocampal formationNeurosciencePsychologyFear conditioning
-
openalex
Tomohisa Toda, Sarah Parylak, Sara B. Linker, Fred H. Gage
2018-04-20
置信度 0.72
NeurogenesisHippocampal formationDentate gyrusHippocampusNeuroscience
-
openalex
Li-Chun Cheng, Érika Pastrana, Masoud Tavazoie, Fiona Doetsch
2009-03-15
置信度 0.72
NeurogenesisSubventricular zoneNeuroblastNeural stem cellBiology
-
openalex
Yi Eve Sun, Mireya Nadal‐Vicens, Stephanie Misono, Michael Z. Lin 等
2001-02-01
置信度 0.72
GliogenesisNeurogenesisBiologyTranscription factorNeural stem cell
-
A recent assertion that new neurons are continually added to the neocortex of adult macaque monkeys has profound implications for understanding the cellular mechanisms of higher cognitive functions. Here we searched for neurogenesis in adult macaques by using …
openalex
David R. Kornack, Pasko Rakić
2001-12-07
置信度 0.72
NeocortexNeurogenesisNeuroscienceOlfactory bulbBromodeoxyuridine
-
There has been a substantial amount of research on the relationship between hippocampal neurogenesis and behaviour over the past fifteen years, but the causal role that new neurons have on cognitive and affective behavioural tasks is still far from clear. This…
arxiv
Stanley E. Lazic
2011-04-29T16:32:00Z
置信度 0.78
q-bio.NCstat.AP
-
Thyroid hormone (TH) signalling, an evolutionary conserved pathway, is crucial for brain function and cognition throughout life, from early development to ageing. In humans, TH deficiency during pregnancy alters offspring brain development, increasing the risk…
arxiv
Jean-David Gothié, Barbara Demeneix, Sylvie Remaud
2019-05-09T12:07:04Z
置信度 0.78
q-bio.SCq-bio.TO
-
Few studies that examine the neurogenesis--behaviour relationship formally establish covariation between neurogenesis and behaviour or rule out competing explanations. The behavioural relevance of neurogenesis might therefore be overestimated if other mechanis…
arxiv
Stanley E. Lazic, Johannes Fuss, Peter Gass
2014-05-21T21:21:02Z
置信度 0.78
q-bio.NCstat.AP
-
Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the context of and adult brai…
arxiv
Guillermo A. Cecchi, Marcelo O. Magnasco
2004-12-16T21:47:46Z
置信度 0.78
q-bio.NC
-
New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered connectivity patter…
arxiv
Casey M. Schneider-Mizell, Jack M. Parent, Eshel Ben-Jacob, Michal Zochowski 等
2009-12-10T22:07:37Z
置信度 0.78
q-bio.NCphysics.bio-ph
-
The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory system? Using a comput…
arxiv
Siu-Fai Chow, Stuart D. Wick, Hermann Riecke
2012-02-09T23:03:57Z
置信度 0.78
q-bio.NCnlin.AO
-
Hippocampal CA3 is crucial for the formation of long-term associative memory. It has a heavily recurrent connectivity, and memories are thought to be stored as memory engrams in the CA3. However, despite its importance for memory storage and retrieval, spiking…
arxiv
Yansong Chua, Cheston Tan
2017-04-25T03:30:28Z
置信度 0.78
q-bio.NC
-
Neural machine learning methods, such as deep neural networks (DNN), have achieved remarkable success in a number of complex data processing tasks. These methods have arguably had their strongest impact on tasks such as image and audio processing - data proces…
arxiv
Timothy J. Draelos, Nadine E. Miner, Christopher C. Lamb, Jonathan A. Cox 等
2016-12-12T16:25:23Z
置信度 0.78
cs.NEcs.LGstat.ML
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The aim of this study was to estimate the number of new cells and neurons added to the dentate gyrus across the lifespan, and to compare the rate of age-associated decline in neurogenesis across species. Data from mice (Mus musculus), rats (Rattus norvegicus),…
arxiv
Stanley E. Lazic
2011-05-03T21:30:46Z
置信度 0.78
q-bio.NCstat.AP
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Lifelong learning capabilities are crucial for artificial autonomous agents operating on real-world data, which is typically non-stationary and temporally correlated. In this work, we demonstrate that dynamically grown networks outperform static networks in in…
arxiv
German I. Parisi, Xu Ji, Stefan Wermter
2018-11-06T01:38:26Z
置信度 0.78
cs.NEcs.LG
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Exposures to a hypomagnetic field can affect biological processes. Recently, it has been observed that hypomagnetic field exposure can adversely affect adult hippocampal neurogenesis and hippocampus-dependent cognition in mice. In the same study, the role of r…
arxiv
Rishabh, Hadi Zadeh-Haghighi, Dennis Salahub, Christoph Simon
2021-10-25T03:19:22Z
置信度 0.78
q-bio.NCphysics.bio-phquant-ph
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Adult neurogenesis has long been documented in the vertebrate brain, and recently even in humans. Although it has been conjectured for many years that its functional role is related to the renewing of memories, no clear mechanism as to how this can be achieved…
arxiv
Guillermo A. Cecchi, Leopoldo T. Petreanu, Arturo Alvarez-Buylla, Marcelo O. Magnasco
2001-05-03T17:00:14Z
置信度 0.78
cond-mat.dis-nnq-bio
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In a continual learning setting, we require a model to be plastic enough to learn a new task and stable enough to not disturb previously learned capabilities. We argue that this dilemma has an architectural root. A finite network has limited representational a…
arxiv
Karthik Charan Raghunathan, Christian Metzner, Laura Kriener, Melika Payvand
2026-04-29T15:04:25Z
置信度 0.78
cs.LGcs.AIcs.NE
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Hierarchical temporal memory (HTM) is a biomimetic sequence memory algorithm that holds promise for invariant representations of spatial and spatiotemporal inputs. This paper presents a comprehensive neuromemristive crossbar architecture for the spatial pooler…
arxiv
Abdullah M. Zyarah, Dhireesha Kudithipudi
2018-12-27T14:27:10Z
置信度 0.78
cs.ETcs.LGstat.ML