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2020-08-28T21:18:50Z
置信度 0.70
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2020-08-28T21:19:03Z
置信度 0.70
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crossref
2019-08-22T04:11:21Z
置信度 0.70
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2020-08-28T21:16:44Z
置信度 0.70
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2020-08-28T21:21:30Z
置信度 0.70
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2020-08-28T21:15:31Z
置信度 0.70
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2020-08-28T21:12:03Z
置信度 0.70
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2020-08-28T21:15:21Z
置信度 0.70
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2007-05-16T09:33:02Z
置信度 0.70
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In this dissertation, we outline our efforts to introduce an advanced MRI imaging technique called Diffusion Tensor Imaging (DTI) to the pediatric brain tumor population. We discuss the theory and application of DTI as it was performed in a series of translati…
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Nicholas Phillips
2017-11-03T17:09:41Z
置信度 0.70
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2020-08-28T21:08:59Z
置信度 0.70
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crossref
2020-08-28T06:15:35Z
置信度 0.70
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References 124 Molecular neuroimaging techniques such as positron emission tomography (PET) have been used for the in vivo assessment of molecular processes at their sites of action, permitting detection of subtle pathophysiological changes in the brain at asy…
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2013-05-28T20:56:04Z
置信度 0.70
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2020-08-28T21:05:12Z
置信度 0.70
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2020-08-28T21:17:42Z
置信度 0.70
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2020-08-28T21:09:23Z
置信度 0.70
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2020-08-28T21:08:25Z
置信度 0.70
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Objective Vertebro-basilar dolichoectasia is an anomaly which has been well-known since the earliest days of clinical neurology. In spite of this neither the mechanism by which it is produced not its clinical importance are fully defined. In this paper we revi…
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2020-08-28T21:07:58Z
置信度 0.70
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2020-08-28T21:11:56Z
置信度 0.70
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2007-05-16T13:33:02Z
置信度 0.70
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2020-08-28T21:22:39Z
置信度 0.70
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The social-cognitive deficits associated with several neurodevelopmental and neuropsychiatric disorders have been linked to structural and functional brain anomalies. Given the recent appreciation for quantitative approaches to behavior, in this study we exami…
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David W. Evans, Steven M. Lazar, K. B. Boomer, Aaron D. Mitchel 等
2014-05-01T10:41:33Z
置信度 0.70
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Recent studies have demonstrated a close relationship between computational acoustic features and neural brain activities, and have largely advanced our understanding of auditory information processing in the human brain. Along this line, we proposed a multidi…
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Xintao Hu, Lei Guo, Junwei Han, Tianming Liu
2016-02-09T09:48:47Z
置信度 0.70
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Background falls are a growing global public health concern that requires our attention and ongoing exploration. Observational studies suggest that changes in certain brain structures are associated with falls and risk factors influencing falls, yet the causal…
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Gengxin Dong, Shuting Peng, Qi Gao, Dapeng Bao
2026-02-11T02:09:25Z
置信度 0.70
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2020-08-28T21:22:44Z
置信度 0.70
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2020-08-28T21:19:23Z
置信度 0.70
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Ronald A. Cohen, Lawrence H. Sweet
2010-12-08T20:23:03Z
置信度 0.70
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2020-08-28T21:12:19Z
置信度 0.70
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2020-08-28T21:13:24Z
置信度 0.70
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2020-08-28T21:05:37Z
置信度 0.70
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2020-08-28T21:17:25Z
置信度 0.70
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2020-08-28T21:11:30Z
置信度 0.70
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2020-08-28T21:12:29Z
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2020-08-28T21:05:53Z
置信度 0.70
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2013-10-23T07:04:25Z
置信度 0.70
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Abstract Over the last 25 years remarkable advances have been made in quantifying brain chemistry and function in living patients. Beginning with primitive xenon techniques through to highly sophisticated positron emission tomography (PET) and functional MRI t…
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Peter Williamson
2023-11-01T21:58:46Z
置信度 0.70
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2020-08-28T21:10:47Z
置信度 0.70
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Andre Obenaus, Jérôme Badaut
2017-09-02T16:58:26Z
置信度 0.70
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The techniques of functional imaging are so complex that it may be tempting to glance at the pictures and assume that the method of production has unimpeachable scientific validity. The use of such images has extended far beyond the neuroscience community, to …
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D. P. Morrish
2002-07-26T22:47:12Z
置信度 0.70
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Soonmee Cha
2010-03-04T01:50:45Z
置信度 0.70
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2018-06-14T22:53:40Z
置信度 0.70
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Purpose First, to investigate the patterns of [ 18 F]-FDOPA positron emission tomography imaging in corticobasal syndrome using visual and semi-quantitative analysis and to compare them with patterns found in Parkinson's disease and progressive supranuclear pa…
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Anaïs El Ouartassi, Caroline Giordana, Aurélie Schiazza, David Chardin 等
2023-07-21T03:21:53Z
置信度 0.70
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In addition to motor symptoms, behavioural complications are commonly found in patients with Parkinson's disease (PD). Behavioural complications, including depression, anxiety, apathy, impulse control disorder and psychosis, together have a large impact on PD …
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Mikaeel Valli, Alexander Mihaescu, Antonio P. Strafella
2017-08-30T02:09:16Z
置信度 0.70
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Better understanding of emotional experience in normal persons may aid in understanding abnormalities in affective disorders. Since depressive symptoms reflect distortions of emotional states that can be expressed by non- depressed subjects, the nature of bloo…
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2020-12-22T18:44:46Z
置信度 0.70
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2020-08-28T21:13:44Z
置信度 0.70
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2023-03-23T04:42:44Z
置信度 0.70
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Jae-Byum Chang
2018-05-14T12:07:50Z
置信度 0.70
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Xi jian Dai, Yang Yang, Yongjun Wang
2022-10-20T04:05:17Z
置信度 0.70
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The integration of expression quantitative trait loci (eQTLs) and genome-wide association study (GWAS) findings to identify causal genes aids in elucidating the biological mechanisms and the discovery of potential drug targets underlying complex traits. This c…
preprints
2024
置信度 0.74
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Magnetic resonance imaging (MRI) is a valuable non-invasive tool that has been widely used for in vivo investigations of brain morphometry and microstructural characteristics. Postmortem MRIs can provide complementary anatomical and microstructural information…
preprints
2024
置信度 0.74
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While some studies have suggested that autonomous sensory meridian response (ASMR) can relieves anxiety, whether ASMR relieves anxiety in trait-anxious individuals and its neural mechanisms remains a question worth exploring. We used the self-threatening n-bac…
preprints
2024
置信度 0.74
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Brain imaging is a high-content modality that offers dense insights into the structure and pathology of the brain. Existing genetic association studies of brain imaging, typically focusing on a number of individual image-derived phenotypes (IDPs), have success…
preprints
2024
置信度 0.74
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Short video addiction refers to a psychological dependency on short video applications, characterized by an intense attachment and an inability to control usage, leading to typical addiction symptoms. While its definition bears similarities to substance addict…
preprints
2024
置信度 0.74
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Confocal microscope has optical sectioning that is accessible for structural and dynamic imaging in in vivo mouse brain. With the requirement of brain-wide field-of-view (FOV) in many neuroscience researches, existing confocal microscope fails to fulfill the r…
preprints
2024
置信度 0.74
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Introduction: Tuberculous meningitis (TBM) leads to high mortality, especially amongst individuals with HIV. Predicting the incidence of disease-related complications is challenging, for which purpose the value of brain magnetic resonance imaging (MRI) has not…
preprints
2024
置信度 0.74
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A long-standing neurobiological explanation of stuttering is the incomplete cerebral dominance theory, which refers to competition between two hemispheres for “dominance” over handedness and speech, causing altered language lateralisation. Renewed interest in …
preprints
2024
置信度 0.74
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ABSTRACT BACKGROUND Ultra-high field MR imaging offers marked gains in signal-to-noise ratio, spatial resolution, and contrast which translate to improved sensitivity for pathology and anatomy. These benefits are particularly relevant for the neonatal brain, a…
preprints
2023
置信度 0.74
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Significance Extending the photoacoustic microscopy (PAM) into the mid-infrared (MIR) molecular fingerprint region constitutes a promising route towards label-free imaging of biological molecular structures. Realizing this objective requires a high-energy nano…
preprints
2024
置信度 0.74
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Background Federated learning (FL) could boost deep learning in neuroimaging but is rarely deployed in a real-world scenario, where its true potential lies. Here, we propose FLightcase, a new FL toolbox tailored for brain research. We tested FLightcase on a re…
preprints
2023
置信度 0.74
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To understand the neurocognitive mechanisms that underlie heterogeneity in cognitive ageing, recent scientific efforts have led to a growing public availability of imaging cohort data. The Advanced BRain Imaging on ageing and Memory (ABRIM) project aims to add…
preprints
2023
置信度 0.74
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Abstract A major challenge in neuroscience is to visualize the structure of the human brain at different scales. Traditional histology reveals micro- and meso-scale brain features, but suffers from staining variability, tissue damage and distortion that impede…
preprints
2024
置信度 0.74
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The utility of chemical exchange saturation transfer (CEST) MRI for monitoring the uptake of glucosamine (GlcN), a safe dietary supplement, has been previously demonstrated in detecting breast cancer in both murine and human subjects. Here, we studied and char…
preprints
2023
置信度 0.74
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The combination of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) at ultra-high field (7 Tesla) offers appealing new possibilities to probe human brain function non-invasively with high coverage, millisecond temporal precision an…
preprints
2024
置信度 0.74
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Zero-inflated outcomes are very common in behavioral data, particularly for responses to psychological questionnaires. Modeling these challenging distributions is further exacerbated by the absence of established statistical models capable of characterizing to…
preprints
2023
置信度 0.74
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Populational brain imaging methods based on group averages provide valuable insights into the general functions of the brain. However, they often overlook the inherent inter- and intra-subject variability, limiting our understanding of individual differences. …
preprints
2023
置信度 0.74
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Optical three-dimensional (3D) molecular imaging is highly desirable for providing precise distribution of the target-of-interest in disease models. However, such 3D imaging is still far from wide applications in biomedical research; 3D brain optical molecular…
preprints
2023
置信度 0.74
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ABSTRACT Importance Poor oral health is a modifiable risk factor that is associated with a variety of health outcomes. However, the relationship between oral and brain health is not well understood. Objective To test the hypothesis that poor oral health is ass…
preprints
2023
置信度 0.74
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We present an extension to the Brain Imaging Data Structure (BIDS) for motion data. Motion data is frequently recordedalongside human brain imaging and electrophysiological data. The goal of Motion-BIDS is to make motion data interoperableacross different labo…
preprints
2023
置信度 0.74
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ABSTRACT Depression is an incapacitating psychiatric disorder with high prevalence in adolescent populations that is influenced by many risk factors, including family history of depression. The ability to predict who may develop depression before adolescence, …
preprints
2023
置信度 0.74
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Major depressive disorder (MDD) is a heritable psychiatric disorder which is considered one of the leading causes of disability world-wide. Improved understanding of its genetic component could inform novel treatment developments, but so far, gaining functiona…
preprints
2023
置信度 0.74
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Significance Functional near-infrared spectroscopy (fNIRS) presents an opportunity to study human brains in every-day activities and environments. However, achieving robust measurements under such dynamic condition remains a significant challenge. Aim The modu…
preprints
2024
置信度 0.74
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Background Although functional MRI (fMRI) in awake marmosets ( Callithrix jacchus ) is fascinating for functional brain mapping and evaluation of brain disease models, it is difficult to launch awake fMRI on scanners with less than 15 cm of bore size. A univer…
preprints
2023
置信度 0.74
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Abstract Temporal focusing two-photon microscopy enables high resolution imaging of fine structures in vivo over a large volume. A limitation of temporal focusing is that signal-to-background ratio and resolution degrade rapidly with increasing imaging depth. …
preprints
2023
置信度 0.74
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The spinal cord and its interactions with the brain are fundamental for movement control and somatosensation. However, brain and spinal cord electrophysiology in humans have largely been treated as distinct enterprises, in part due to the relative inaccessibil…
preprints
2022
置信度 0.74
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ABSTRACT In vivo, brain imaging poses several challenges due to the complexity of brain tissue and the requirements for effective and safe imaging. In this manuscript, we reported on developing a new fluorescent dye, Cy5-PEG2, that can selectively accumulate i…
preprints
2023
置信度 0.74
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Autism spectrum disorder (ASD) is a common neurodevelopmental condition. The American Academy of Paediatrics and American Academy of Neurology do not recommend routine brain magnetic resonance imaging (MRI) in the assessment of ASD. The need for a brain MRI sh…
preprints
2022
置信度 0.74
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Dissecting the neurobiology of dance would shed light on a complex, yet ubiquitous, form of human communication. In this experiment, we sought to study, via mobile electroencephalography (EEG), the brain activity of five experienced dancers while dancing butoh…
preprints
2023
置信度 0.74
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Cannabis use during adolescence and young adulthood has been associated with brain structure and functional connectivity, yet despite a rapid increase in cannabis use among older adults in the past decade, the impact on brain structure and function in this pop…
preprints
2023
置信度 0.74
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Much of human culture’s advanced technology owes its existence to the ability to mentally manipulate quantities. Neuroscience has described the brain regions overall recruited by numerical tasks and the neuronal codes representing individual quantities during …
preprints
2023
置信度 0.74
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BackgroundLong-term pain is a common health problem that results in disability for patients of all ages, leading to an enormous economic burden. Over 20% of the population suffer from long-term pain. Unfortunately, there are no clinical tests that predicts who…
preprints
2024
置信度 0.74
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We develop a data harmonization approach for C. elegans volumetric microscopy data, still or video, consisting of a standardized format, data pre-processing techniques, and a set of human-in-the-loop machine learning based analysis software tools. We unify a d…
preprints
2024
置信度 0.74
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We previously developed a fully automated spherical aberration compensation microscope system, Deep-C, to obtain spherical aberration-free images, but the contrast-based algorithm (Peak-C) may limit applications for low signal-to-noise ratio images. Herein we …
preprints
2022
置信度 0.74
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Abstract This study aimed to validate the causal associations of brain structures with osteoarthritis (OA) and then describe key causal genes and proteins in brain related to OA risk. To explore the genetic correlation and causal relationship between brain str…
preprints
2024
置信度 0.74
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As an anatomical extension of the brain, the retina of the eye is synaptically connected to the visual cortex, establishing physiological connections between the eye and the brain. Despite the unique opportunity retinal structures offer for assessing brain dis…
preprints
2023
置信度 0.74
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The invention of the miniaturized microscope has enabled neuroscientists to investigate neural mechanisms in freely moving mice. A lot of efforts have been made to optimize performance of the miniaturized microscope. However, the tethered cables limit the abil…
preprints
2022
置信度 0.74
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According to the language of thought hypothesis, regular sequences are compressed in human memory using recursive loops akin to a mental program that predicts future items. We tested this theory by probing memory for 16-item sequences made of two sounds. We re…
preprints
2022
置信度 0.74
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Abstract Genome-wide association studies of brain imaging phenotypes are mainly performed in European populations, but other populations are severely under-represented. Here, we conducted Chinese-alone and trans-ancestral genome-wide association studies of 3,4…
preprints
2022
置信度 0.74
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Recent development of large-scale activity imaging of neuronal ensembles provides opportunities for understanding how activity patterns are generated in the brain and how information is transmitted between neurons or neuronal ensembles. However, methodologies …
preprints
2022
置信度 0.74
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ABSTRACT To embrace big-data neuroimaging, harmonization of site effect in resting-state functional magnetic resonance imaging (R-fMRI) data fusion is a fundamental challenge. Comprehensive evaluation of potentially effective harmonization strategies, particul…
preprints
2022
置信度 0.74
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Abstract Gonadal hormone fluctuations in females have been associated with symptoms of mental health, yet the underlying brain mechanisms remain understudied. Recent advances in neuroscience have shifted the paradigm towards longitudinal tracking, enabling the…
preprints
2023
置信度 0.74
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We performed a genome-wide association study of 143,067 highly polymorphic short tandem repeats (STRs) with MRI brain grey matter volumes (GMVs) on 10,702 UK Biobank (UKB) participants, including 8,751 in the discovery stage and 1,701 in the replication analys…
preprints
2023
置信度 0.74
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Machine learning studies have shown that various phenotypes can be predicted from structural and functional brain images. However, in most such studies, prediction performance ranged from moderate to disappointing. It is unclear whether prediction performance …
preprints
2022
置信度 0.74
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Non-human primate (NHP) studies are unique in translational research, especially in neurosciences and neuroimaging approaches are a preferred method for scaling cross-species comparative neurosciences. In this regard, neuroimaging database development and shar…
preprints
2023
置信度 0.74
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Object: Autistic traits (ATs) were frequently reported in children with attention-deficit/hyperactive disorder (ADHD). This study aimed to examine ATs in children with ADHD from both behavioral and neuroimaging aspects. Method: The Autism Spectrum Screening Qu…
preprints
2023
置信度 0.74
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While the genetics of MS risk susceptibility are well-described, the genetics of disease progression remain elusive. We therefore investigated the genetic determinants of MS progression on longitudinal brain MRI: change in brain volume (BV); and change in T2 l…
preprints
2023
置信度 0.74
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Brain-imaging research enjoys increasing adoption of supervised machine learning for singlesubject disease classification. Yet, the success of these algorithms likely depends on population diversity, including demographic differences and other factors that may…
preprints
2021
置信度 0.74
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As SARS-CoV-2 infections have been shown to affect the central nervous system, the investigation of associated alterations of brain structure and neuropsychological sequelae is crucial to help address future health care needs. Therefore, we performed a compreh…
preprints
2022
置信度 0.74
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Data-driven discovery of image-derived phenotypes (IDPs) from large-scale multimodal brain imaging data has enormous potential for neuroscientific and clinical research by linking IDPs to subjects’ demographic, behavioural, clinical and cognitive measures (i.e…
preprints
2021
置信度 0.74
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Understanding the genetic architecture of brain structure is challenging, partly due to difficulties in designing robust, non-biased descriptors of brain morphology. Until recently, brain measures for genome-wide association studies (GWAS) consisted of traditi…
preprints
2022
置信度 0.74
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Registration of data to a common frame of reference is an essential step in the analysis and integration of diverse neuroscientific data modalities. To this end, volumetric brain atlases enable histological datasets to be spatially registered and analysed, yet…
preprints
2022
置信度 0.74